This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
17α-Hydroxyprogesterone
catalog :
H5752
citations: 61
Reference
Hird B, Tetlow L, Tobi S, Patel L, Clayton P. No evidence of an increase in early infant mortality from congenital adrenal hyperplasia in the absence of screening. Arch Dis Child. 2014;99:158-64 pubmed publisher
Knowles R, Khalid J, Oerton J, Hindmarsh P, Kelnar C, Dezateux C. Late clinical presentation of congenital adrenal hyperplasia in older children: findings from national paediatric surveillance. Arch Dis Child. 2014;99:30-4 pubmed publisher
Reisch N, Rottenkolber M, Greifenstein A, Krone N, Schmidt H, Reincke M, et al. Testicular adrenal rest tumors develop independently of long-term disease control: a longitudinal analysis of 50 adult men with congenital adrenal hyperplasia due to classic 21-hydroxylase deficiency. J Clin Endocrinol Metab. 2013;98:E1820-6 pubmed publisher
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Kline L, Karpinski E. A comparison of the effects of various sex steroids on cholecystokinin- and KCl-induced tension in female guinea pig gallbladder strips. Gen Comp Endocrinol. 2013;185:37-43 pubmed publisher
Oswiecimska J, Ksiazek A, Sygulla K, Pys Spychala M, Roczniak G, Roczniak W, et al. Androgens concentrations and second-to fourth-digit ratio (2D:4D) in girls with congenital adrenal hyperplasia (21-hydroxylase deficiency). Neuro Endocrinol Lett. 2012;33:787-91 pubmed
Deveci K, Gokakin A, Boztosun A, Deveci H, Senel S, Uslu A, et al. Serum 17-OH progesterone and free testosterone levels in women patients with Familial Mediterranean Fever: a pivotal study. Eur Rev Med Pharmacol Sci. 2013;17:261-5 pubmed
Roth M, Nya Ngatchou J, Lin K, Page S, Anawalt B, Matsumoto A, et al. Androgen synthesis in the gonadotropin-suppressed human testes can be markedly suppressed by ketoconazole. J Clin Endocrinol Metab. 2013;98:1198-206 pubmed publisher
Kamrath C, Hartmann M, Wudy S. Androgen synthesis in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Horm Metab Res. 2013;45:86-91 pubmed publisher
Bizzarri C, Crea F, Marini R, Benevento D, Porzio O, Rava L, et al. Clinical features suggestive of non-classical 21-hydroxylase deficiency in children presenting with precocious pubarche. J Pediatr Endocrinol Metab. 2012;25:1059-64 pubmed publisher
Kamrath C, Hartmann M, Wudy S. [The alternative androgen synthesis pathway in humans]. Klin Padiatr. 2013;225:3-7 pubmed publisher
Kulle A, Welzel M, Holterhus P, Riepe F. Implementation of a liquid chromatography tandem mass spectrometry assay for eight adrenal C-21 steroids and pediatric reference data. Horm Res Paediatr. 2013;79:22-31 pubmed publisher
Shrivastav T, Chaube S, Kariya K, Prasad P, Kumar D. Influence of different length spacers containing enzyme conjugate on functional parameters of progesterone ELISA. J Immunoassay Immunochem. 2013;34:94-108 pubmed publisher
Romero R, Yeo L, Miranda J, Hassan S, Conde Agudelo A, Chaiworapongsa T. A blueprint for the prevention of preterm birth: vaginal progesterone in women with a short cervix. J Perinat Med. 2013;41:27-44 pubmed publisher
Fernandes D, Dimastrogiovanni G, Blázquez M, Porte C. Metabolism of the polycyclic musk galaxolide and its interference with endogenous and xenobiotic metabolizing enzymes in the European sea bass (Dicentrarchus labrax). Environ Pollut. 2013;174:214-21 pubmed publisher
Lekarev O, Tafuri K, Lane A, Zhu G, Nakamoto J, Buller Burckle A, et al. Erroneous prenatal diagnosis of congenital adrenal hyperplasia owing to a duplication of the CYP21A2 gene. J Perinatol. 2013;33:76-8 pubmed publisher
Singh S, Akhtar N, Ahmad J. Plasma adiponectin levels in women with polycystic ovary syndrome: impact of metformin treatment in a case-control study. Diabetes Metab Syndr. 2012;6:207-11 pubmed publisher
Nascimento A, Silva Lara L, Japur de Sá Rosa e Silva A, Ferriani R, Reis R. Effects of metformin on serum insulin and anti-Mullerian hormone levels and on hyperandrogenism in patients with polycystic ovary syndrome. Gynecol Endocrinol. 2013;29:246-9 pubmed publisher
Kim H, Kang M, Kim J, Kim S, Chung J, Min Y, et al. A case of congenital adrenal hyperplasia mimicking Cushing's syndrome. J Korean Med Sci. 2012;27:1439-43 pubmed publisher
Onder A, Aycan Z, Cetinkaya S, Kendirci H, Baş V, Ağladioğlu S. Assessment of the 21-hydroxylase deficiency and the adrenal functions in young females with Turner syndrome. J Pediatr Endocrinol Metab. 2012;25:681-5 pubmed
Yu H, Bian X, Liu J, Hu X, Zhou Q. [Pregnancy outcomes of eight pregnant women with congenital adrenal hyperplasia due to 21-hydroxylase deficiency]. Zhonghua Fu Chan Ke Za Zhi. 2012;47:651-4 pubmed
Wang H, Tian Q, Sun A, Yao F, Kang X, Zhang Y, et al. [Clinical study on 48 cases with complete 17α-hydroxylase deficiency]. Zhonghua Fu Chan Ke Za Zhi. 2012;47:518-21 pubmed
Medina S, Ferreres F, García Viguera C, Horcajada M, Orduna J, Savirón M, et al. Non-targeted metabolomic approach reveals urinary metabolites linked to steroid biosynthesis pathway after ingestion of citrus juice. Food Chem. 2013;136:938-46 pubmed publisher
Hoehn T, Lukacs Z, Stehn M, Mayatepek E, Philavanh K, Bounnack S. Establishment of the first newborn screening program in the People's Democratic Republic of Laos. J Trop Pediatr. 2013;59:95-9 pubmed publisher
Cabaleiro J. Best practice recommendations for compounding 17-hydroxyprogesterone. Int J Pharm Compd. 2012;16:86-7 pubmed
De Amicis F, Santoro M, Guido C, Sisci D, Bruno R, Carpino A, et al. Progesterone through progesterone receptors affects survival and metabolism of pig sperm. Anim Reprod Sci. 2012;135:75-84 pubmed publisher
Roth M, Lin K, Bay K, Amory J, Anawalt B, Matsumoto A, et al. Serum insulin-like factor 3 is highly correlated with intratesticular testosterone in normal men with acute, experimental gonadotropin deficiency stimulated with low-dose human chorionic gonadotropin: a randomized, controlled trial. Fertil Steril. 2013;99:132-9 pubmed publisher
van der Pas R, Hofland L, Hofland J, Taylor A, Arlt W, Steenbergen J, et al. Fluconazole inhibits human adrenocortical steroidogenesis in vitro. J Endocrinol. 2012;215:403-12 pubmed publisher
Németh S, Riedl S, Kriegshäuser G, Baumgartner Parzer S, Concolino P, Neocleous V, et al. Reverse-hybridization assay for rapid detection of common CYP21A2 mutations in dried blood spots from newborns with elevated 17-OH progesterone. Clin Chim Acta. 2012;414:211-4 pubmed publisher
Caritis S, Simhan H, Zhao Y, Rouse D, Peaceman A, Sciscione A, et al. Relationship between 17-hydroxyprogesterone caproate concentrations and gestational age at delivery in twin gestation. Am J Obstet Gynecol. 2012;207:396.e1-8 pubmed publisher
Bellavance E, Luu The V, Poirier D. Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone. J Med Chem. 2009;52:7488-502 pubmed publisher
Yuan J, Johnson R, Huang R, Wichterman J, Jiang H, Hayton K, et al. Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nat Chem Biol. 2009;5:765-71 pubmed publisher
Leroy V, de Seigneux S, Agassiz V, Hasler U, Rafestin Oblin M, Vinciguerra M, et al. Aldosterone activates NF-kappaB in the collecting duct. J Am Soc Nephrol. 2009;20:131-44 pubmed publisher
Cherkasov A, Ban F, Santos Filho O, Thorsteinson N, Fallahi M, Hammond G. An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin. J Med Chem. 2008;51:2047-56 pubmed publisher
Baert B, Deconinck E, Van Gele M, Slodicka M, Stoppie P, Bodé S, et al. Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorg Med Chem. 2007;15:6943-55 pubmed
Elvers L, Loeber J, Dhondt J, Fukushi M, Hannon W, Torresani T, et al. First ISNS Reference Preparation for Neonatal Screening for thyrotropin, phenylalanine and 17alpha-hydroxyprogesterone in blood spots. J Inherit Metab Dis. 2007;30:609 pubmed
Diamandis P, Wildenhain J, Clarke I, Sacher A, Graham J, Bellows D, et al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007;3:268-73 pubmed
Tonetto Fernandes V, Lemos Marini S, Kuperman H, Ribeiro Neto L, Verreschi I, Kater C. Serum 21-Deoxycortisol, 17-Hydroxyprogesterone, and 11-deoxycortisol in classic congenital adrenal hyperplasia: clinical and hormonal correlations and identification of patients with 11beta-hydroxylase deficiency among a large group with alleged 21-h. J Clin Endocrinol Metab. 2006;91:2179-84 pubmed
Chiang E, Smith D, Selhub J, Dallal G, Wang Y, Roubenoff R. Inflammation causes tissue-specific depletion of vitamin B6. Arthritis Res Ther. 2005;7:R1254-62 pubmed
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Jensen T, Klarlund M, Hansen M, Jensen K, Skjødt H, Hyldstrup L. Connective tissue metabolism in patients with unclassified polyarthritis and early rheumatoid arthritis. Relationship to disease activity, bone mineral density, and radiographic outcome. J Rheumatol. 2004;31:1698-708 pubmed
Straub R, Weidler C, Demmel B, Herrmann M, Kees F, Schmidt M, et al. Renal clearance and daily excretion of cortisol and adrenal androgens in patients with rheumatoid arthritis and systemic lupus erythematosus. Ann Rheum Dis. 2004;63:961-8 pubmed
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Gupta M, Guryev O, Auchus R. 5alpha-reduced C21 steroids are substrates for human cytochrome P450c17. Arch Biochem Biophys. 2003;418:151-60 pubmed
Bolt R, van Weissenbruch M, Popp Snijders C, Sweep F, Lafeber H, Delemarre van de Waal H. Maturity of the adrenal cortex in very preterm infants is related to gestational age. Pediatr Res. 2002;52:405-10 pubmed
Deng C, Shang C, Hu Y, Zhang X. Rapid diagnosis of phenylketonuria and other aminoacidemias by quantitative analysis of amino acids in neonatal blood spots by gas chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2002;775:115-20 pubmed
Escobar Morreale H, San Millan J, Smith R, Sancho J, Witchel S. The presence of the 21-hydroxylase deficiency carrier status in hirsute women: phenotype-genotype correlations. Fertil Steril. 1999;72:629-38 pubmed
Ibanez L, de Zegher F, Potau N. Anovulation after precocious pubarche: early markers and time course in adolescence. J Clin Endocrinol Metab. 1999;84:2691-5 pubmed
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al Saedi S, Dean H, Dent W, Cronin C. Reference ranges for serum cortisol and 17-hydroxyprogesterone levels in preterm infants. J Pediatr. 1995;126:985-7 pubmed
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Toscano V, Sancesario G, Bianchi P, Cicardi C, Casilli D, Giacomini P. Cerebrospinal fluid estrone in pseudotumor cerebri: a change in cerebral steroid hormone metabolism?. J Endocrinol Invest. 1991;14:81-6 pubmed
Hampl R, Lachman M, Novak Z, Sulcova J, Starka L. Serum levels of steroid hormones in men with varicocele and oligospermia as compared to normozoospermic men. Exp Clin Endocrinol. 1992;100:117-9 pubmed
product information
Catalog Number :
H5752
Product Name :
17α-Hydroxyprogesterone
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥90%5
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA