This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Erythropoietin human
catalog :
H5166
citations: 100
Reference
Zhang H, Li X, Kan Y, Yang F, Hou Y, Du Y. Analysis of the correlation between serum resistin and the variability of erythropoietin responsiveness in patients with chronic kidney disease. Exp Ther Med. 2015;10:1925-1930 pubmed
Kostić I, Fidalgo Carvalho I, Aday S, Vazão H, Carvalheiro T, Grãos M, et al. Lysophosphatidic acid enhances survival of human CD34(+) cells in ischemic conditions. Sci Rep. 2015;5:16406 pubmed publisher
Liang R, Camprecios G, Kou Y, McGrath K, Nowak R, Catherman S, et al. A Systems Approach Identifies Essential FOXO3 Functions at Key Steps of Terminal Erythropoiesis. PLoS Genet. 2015;11:e1005526 pubmed publisher
Giampietro C, Deflorian G, Gallo S, di Matteo A, Pradella D, Bonomi S, et al. The alternative splicing factor Nova2 regulates vascular development and lumen formation. Nat Commun. 2015;6:8479 pubmed publisher
Li Y, Chen S, Chien C. Erythropoietin produced by genetic-modified NIH/3T3 fibroblasts enhances the survival of degenerating neurons. Brain Behav. 2015;5:e00356 pubmed publisher
Irrera N, Bitto A, Pizzino G, Vaccaro M, Squadrito F, Galeano M, et al. Epoetin Alpha and Epoetin Zeta: A Comparative Study on Stimulation of Angiogenesis and Wound Repair in an Experimental Model of Burn Injury. Biomed Res Int. 2015;2015:968927 pubmed publisher
Chen Y, Chou C, Sun C. Impairment of the Cellular Distribution and Stability of the Erythropoietin Receptor Through the Direct Targeting of Aristolochic Acid. Toxicol Sci. 2015;147:246-54 pubmed publisher
Thomas S, Fisher K, Snowden J, Danson S, Brown S, Zeidler M. Methotrexate Is a JAK/STAT Pathway Inhibitor. PLoS ONE. 2015;10:e0130078 pubmed publisher
Kim Y, Kim H, Baek E, Kurita R, Cha H, Nakamura Y, et al. Rh D blood group conversion using transcription activator-like effector nucleases. Nat Commun. 2015;6:7451 pubmed publisher
Lee E, Kim M, Park B, Kim J, Choi G, Lee J, et al. Avoiding unnecessary blood transfusions in women with profound anaemia. Aust N Z J Obstet Gynaecol. 2015;55:262-7 pubmed publisher
Singh P, Devasahayam M, Devi S. Expression of GPI anchored human recombinant erythropoietin in CHO cells is devoid of glycosylation heterogeneity. Indian J Exp Biol. 2015;53:195-201 pubmed
Capitano M, Chitteti B, Cooper S, Srour E, Bartke A, Broxmeyer H. Ames hypopituitary dwarf mice demonstrate imbalanced myelopoiesis between bone marrow and spleen. Blood Cells Mol Dis. 2015;55:15-20 pubmed publisher
Li K, Cao R, Zhu X, Liu X, Li L, Cui S. Erythropoietin Attenuates the Apoptosis of Adult Neurons After Brachial Plexus Root Avulsion by Downregulating JNK Phosphorylation and c-Jun Expression and Inhibiting c-PARP Cleavage. J Mol Neurosci. 2015;56:917-925 pubmed publisher
Malik J, Getman M, Steiner L. Histone methyltransferase Setd8 represses Gata2 expression and regulates erythroid maturation. Mol Cell Biol. 2015;35:2059-72 pubmed publisher
Kummalue T, Inoue T, Miura Y, Narusawa M, Inoue H, Komatsu N, et al. Ribosomal protein L11- and retinol dehydrogenase 11-induced erythroid proliferation without erythropoietin in UT-7/Epo erythroleukemic cells. Exp Hematol. 2015;43:414-423.e1 pubmed publisher
Lindahl K, Hörnfeld E, Stahle L, Carlsson T, Weiland O, Parke Å, et al. High-Dose Ribavirin Enhances Early Virological Response in Hepatitis C Genotype 1-Infected Patients. Ther Drug Monit. 2015;37:745-50 pubmed publisher
Caillaud C, Mechta M, Ainge H, Madsen A, Ruell P, Mas E, et al. Chronic erythropoietin treatment improves diet-induced glucose intolerance in rats. J Endocrinol. 2015;225:77-88 pubmed publisher
Weltert L, Rondinelli B, Bello R, Falco M, Bellisario A, Maselli D, et al. A single dose of erythropoietin reduces perioperative transfusions in cardiac surgery: results of a prospective single-blind randomized controlled trial. Transfusion. 2015;55:1644-54 pubmed publisher
Abbott A. Neuroscience: The brain, interrupted. Nature. 2015;518:24-6 pubmed publisher
Harzallah A, Zouaghi K, Dridi A, Boubaker K, Beji S, Ayari M, et al. Therapeutic efficacy of a biosimilar epoetin alfa in hemodialysis patients. Saudi J Kidney Dis Transpl. 2015;26:78-82 pubmed
Rubab Z, Amin H, Abbas K, Hussain S, Ullah M, Mohsin S. Serum hepcidin levels in patients with end-stage renal disease on hemodialysis. Saudi J Kidney Dis Transpl. 2015;26:19-25 pubmed
Cancarini A, Costagliola C, dell Omo R, Romano M, Morescalchi F, Agnifili L, et al. Effect of intravitreal bevacizumab on serum, aqueous, and vitreous humor levels of erythropoietin in patients with proliferative diabetic retinopathy. Minerva Endocrinol. 2014;39:305-11 pubmed
Grasso G, Buemi M, Giambartino F. The role of erythropoietin in aneurysmal subarachnoid haemorrhage: from bench to bedside. Acta Neurochir Suppl. 2015;120:75-80 pubmed publisher
Li J, Hale J, Bhagia P, Xue F, Chen L, Jaffray J, et al. Isolation and transcriptome analyses of human erythroid progenitors: BFU-E and CFU-E. Blood. 2014;124:3636-45 pubmed publisher
Langdon J, Barkataki S, Berger A, Cheadle C, Xue Q, Sung V, et al. RAP-011, an activin receptor ligand trap, increases hemoglobin concentration in hepcidin transgenic mice. Am J Hematol. 2015;90:8-14 pubmed publisher
Leuchter R, Gui L, Poncet A, Hagmann C, Lodygensky G, Martin E, et al. Association between early administration of high-dose erythropoietin in preterm infants and brain MRI abnormality at term-equivalent age. JAMA. 2014;312:817-24 pubmed publisher
Babushok D, Cardamone D, Rulander N, Master S, Hexner E. A common, under-recognized cause of elevated serum erythropoietin. Am J Med. 2014;127:e7-8 pubmed publisher
Shen W, Chung S, Irhimeh M, Li S, Lee S, Gillies M. Systemic administration of erythropoietin inhibits retinopathy in RCS rats. PLoS ONE. 2014;9:e104759 pubmed publisher
Johnson D, Pascoe E, Badve S, Dalziel K, Cass A, Clarke P, et al. A randomized, placebo-controlled trial of pentoxifylline on erythropoiesis-stimulating agent hyporesponsiveness in anemic patients with CKD: the Handling Erythropoietin Resistance With Oxpentifylline (HERO) trial. Am J Kidney Dis. 2015;65:49-57 pubmed publisher
Miskowiak K, Ehrenreich H, Christensen E, Kessing L, Vinberg M. Recombinant human erythropoietin to target cognitive dysfunction in bipolar disorder: a double-blind, randomized, placebo-controlled phase 2 trial. J Clin Psychiatry. 2014;75:1347-55 pubmed publisher
Bennett C, Bian J. Erythropoiesis-stimulating agents and quality of life: personal journeys of a cancer survivor, oncologist, and two cancer health services researchers. Br J Cancer. 2014;111:421-3 pubmed publisher
Robertson C, Hannay H, Yamal J, Gopinath S, Goodman J, Tilley B, et al. Effect of erythropoietin and transfusion threshold on neurological recovery after traumatic brain injury: a randomized clinical trial. JAMA. 2014;312:36-47 pubmed publisher
Rineau E, Chaudet A, Carlier L, Bizot P, Lasocki S. Ferric carboxymaltose increases epoetin-α response and prevents iron deficiency before elective orthopaedic surgery. Br J Anaesth. 2014;113:296-8 pubmed publisher
Woo M, Hawkins M. Beyond erythropoiesis: emerging metabolic roles of erythropoietin. Diabetes. 2014;63:2229-31 pubmed publisher
Lamrani L, Lacout C, Ollivier V, Denis C, Gardiner E, Ho Tin Noe B, et al. Hemostatic disorders in a JAK2V617F-driven mouse model of myeloproliferative neoplasm. Blood. 2014;124:1136-45 pubmed publisher
Berhane H, Shinde A, Kalash R, Xu K, Epperly M, Goff J, et al. Amelioration of radiation-induced oral cavity mucositis and distant bone marrow suppression in fanconi anemia Fancd2-/- (FVB/N) mice by intraoral GS-nitroxide JP4-039. Radiat Res. 2014;182:35-49 pubmed publisher
Hwang S, Lee S, Park S, Chitteti B, Srour E, Cooper S, et al. Nonmarrow hematopoiesis occurs in a hyaluronic-acid-rich node and duct system in mice. Stem Cells Dev. 2014;23:2661-71 pubmed publisher
Merino J, Bellver Landete V, Oset Gasque M, Cubelos B. CXCR4/CXCR7 molecular involvement in neuronal and neural progenitor migration: focus in CNS repair. J Cell Physiol. 2015;230:27-42 pubmed publisher
Krishnan M, Nissenson A. New alternatives in anemia treatment: biosimilars and HIF stabilizers. Nephrol News Issues. 2014;28:24-8 pubmed
Uziel O, Kanfer G, Beery E, Yelin D, Shepshelovich D, Bakhanashvili M, et al. The effects of erythropoietin signaling on telomerase regulation in non-erythroid malignant and non-malignant cells. Biochem Biophys Res Commun. 2014;450:274-82 pubmed publisher
Kautz L, Jung G, Valore E, Rivella S, Nemeth E, Ganz T. Identification of erythroferrone as an erythroid regulator of iron metabolism. Nat Genet. 2014;46:678-84 pubmed publisher
Jaspers A, Baron F, Willems E, Seidel L, Hafraoui K, Vanstraelen G, et al. Erythropoietin therapy after allogeneic hematopoietic cell transplantation: a prospective, randomized trial. Blood. 2014;124:33-41 pubmed publisher
Lestz R, Fivush B, Atkinson M. Association of higher erythropoiesis stimulating agent dose and mortality in children on dialysis. Pediatr Nephrol. 2014;29:2021-8 pubmed publisher
Mäenpää J, Puistola U, Riska H, Sintonen H, Saarni O, Juvonen E, et al. Impact of Epoetin-beta on anemia and health-related quality of life in cancer patients: a prospective observational study using the generic 15D instrument. Anticancer Res. 2014;34:2325-9 pubmed
Jin W, Ming X, Hou X, Zhu T, Yuan B, Wang J, et al. Protective effects of erythropoietin in traumatic spinal cord injury by inducing the Nrf2 signaling pathway activation. J Trauma Acute Care Surg. 2014;76:1228-34 pubmed publisher
Bu Y, Su F, Wang X, Gao H, Lei L, Chang N, et al. Protein tyrosine phosphatase PTPN9 regulates erythroid cell development through STAT3 dephosphorylation in zebrafish. J Cell Sci. 2014;127:2761-70 pubmed publisher
Ratilal B, Arroja M, Rocha J, Fernandes A, Barateiro A, Brites D, et al. Neuroprotective effects of erythropoietin pretreatment in a rodent model of transient middle cerebral artery occlusion. J Neurosurg. 2014;121:55-62 pubmed publisher
Kim Y, Mungunsukh O, McCart E, Roehrich P, Yee D, Day R. Mechanism of erythropoietin regulation by angiotensin II. Mol Pharmacol. 2014;85:898-908 pubmed publisher
Suragani R, Cadena S, Cawley S, Sako D, Mitchell D, Li R, et al. Transforming growth factor-? superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis. Nat Med. 2014;20:408-14 pubmed publisher
Alnaeeli M, Raaka B, Gavrilova O, Teng R, Chanturiya T, Noguchi C. Erythropoietin signaling: a novel regulator of white adipose tissue inflammation during diet-induced obesity. Diabetes. 2014;63:2415-31 pubmed publisher
Tatarelli C, Piccioni A, Maurillo L, Naso V, Battistini R, D Andrea M, et al. Recombinant human erythropoietin in very elderly patients with myelodysplastic syndromes: results from a retrospective study. Ann Hematol. 2014;93:1413-20 pubmed publisher
Barbosa C, Romão L. Translation of the human erythropoietin transcript is regulated by an upstream open reading frame in response to hypoxia. RNA. 2014;20:594-608 pubmed publisher
Aguilar C, Aguilar C, López Marure R, Jiménez Sánchez A, Rocha Zavaleta L. Co-stimulation with stem cell factor and erythropoietin enhances migration of c-Kit expressing cervical cancer cells through the sustained activation of ERK1/2. Mol Med Rep. 2014;9:1895-902 pubmed publisher
Seed T, Inal C, Singh V. Radioprotection of hematopoietic progenitors by low dose amifostine prophylaxis. Int J Radiat Biol. 2014;90:594-604 pubmed publisher
Winkelmayer W, Mitani A, Goldstein B, Brookhart M, Chertow G. Trends in anemia care in older patients approaching end-stage renal disease in the United States (1995-2010). JAMA Intern Med. 2014;174:699-707 pubmed
Stoyanoff T, Todaro J, Aguirre M, Zimmermann M, Brandan N. Amelioration of lipopolysaccharide-induced acute kidney injury by erythropoietin: involvement of mitochondria-regulated apoptosis. Toxicology. 2014;318:13-21 pubmed publisher
Gardner D, Welham S, Dunford L, McCulloch T, Hodi Z, Sleeman P, et al. Remote conditioning or erythropoietin before surgery primes kidneys to clear ischemia-reperfusion-damaged cells: a renoprotective mechanism?. Am J Physiol Renal Physiol. 2014;306:F873-84 pubmed publisher
Mohammadpour A, Nazemian F, Khaiat M, Tafaghodi M, Salari P, Charkazi S, et al. Evaluation of the effect of pentoxifylline on erythropoietin-resistant anemia in hemodialysis patients. Saudi J Kidney Dis Transpl. 2014;25:73-8 pubmed
So Osman C, Nelissen R, Koopman van Gemert A, Kluyver E, Pöll R, Onstenk R, et al. Patient blood management in elective total hip- and knee-replacement surgery (part 2): a randomized controlled trial on blood salvage as transfusion alternative using a restrictive transfusion policy in patients with a preoperative hemoglobin above 1. Anesthesiology. 2014;120:852-60 pubmed publisher
So Osman C, Nelissen R, Koopman van Gemert A, Kluyver E, Pöll R, Onstenk R, et al. Patient blood management in elective total hip- and knee-replacement surgery (Part 1): a randomized controlled trial on erythropoietin and blood salvage as transfusion alternatives using a restrictive transfusion policy in erythropoietin-eligible pat. Anesthesiology. 2014;120:839-51 pubmed publisher
Liu X, Wu H. [Progress on neuroprotective effects of erythropoietin]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2013;42:693-9 pubmed
McCarthy J, Hocum C, Albright R, Rogers J, Gallaher E, Steensma D, et al. Biomedical system dynamics to improve anemia control with darbepoetin alfa in long-term hemodialysis patients. Mayo Clin Proc. 2014;89:87-94 pubmed publisher
Wang P, Dong S, Shieh J, Peguero E, Hendrickson R, Moore M, et al. Erythropoietin derived by chemical synthesis. Science. 2013;342:1357-1360 pubmed publisher
Mohd Slim M, Shaik R. Pure red cell aplasia associated with recombinant erythropoietin: a case report and brief review of the literature. N Z Med J. 2013;126:106-10 pubmed
Kim S, Chin Y, Heo T. Erythropoietic agents from natural sources. Altern Ther Health Med. 2013;19:54-60 pubmed
Salomon Andonie J, Miasnikova G, Sergueeva A, Polyakova L, Niu X, Nekhai S, et al. Effect of congenital upregulation of hypoxia inducible factors on percentage of fetal hemoglobin in the blood. Blood. 2013;122:3088-9 pubmed publisher
Lin D, Lin E, Tran M. Efficacy and safety of erythropoietin and intravenous iron in perioperative blood management: a systematic review. Transfus Med Rev. 2013;27:221-34 pubmed publisher
Tahan F, Akar H, Dursun I, Yilmaz K. Desensitization of darbepoetin-α: a case report. Eur Ann Allergy Clin Immunol. 2013;45:176-7 pubmed
Wei X, Li Y, Sun X, Zhu X, Feng Y, Liu J, et al. Erythropoietin protects against murine cerebral malaria through actions on host cellular immunity. Infect Immun. 2014;82:165-73 pubmed publisher
Bulut G, Sulahian R, Yao H, Huang L. Cbl ubiquitination of p85 is essential for Epo-induced EpoR endocytosis. Blood. 2013;122:3964-72 pubmed publisher
Cikrikcioglu M, Karatoprak C, Cakirca M, Kiskaç M, Zorlu M, Cetin G, et al. Association of calcium channel blocker use with lower hemoglobin levels in chronic kidney disease. Eur Rev Med Pharmacol Sci. 2013;17:2530-7 pubmed
Means R. Anemia of inflammation: clinical insights from mechanisms. Rinsho Ketsueki. 2013;54:1596-602 pubmed
Pol S. HCV, ribavirin, and anemia: a new dawn. Gastroenterology. 2013;145:930-3 pubmed publisher
Joshi D, Abraham D, Shiwen X, Baker D, Tsui J. Potential role of erythropoietin receptors and ligands in attenuating apoptosis and inflammation in critical limb ischemia. J Vasc Surg. 2014;60:191-201, 201.e1-2 pubmed publisher
Lundgrin E, Janocha A, Koch C, Gebremedhin A, Di Rienzo A, Alkorta Aranburu G, et al. Plasma hepcidin of Ethiopian highlanders with steady-state hypoxia. Blood. 2013;122:1989-91 pubmed publisher
Badve S, Beller E, Cass A, Francis D, Hawley C, Macdougall I, et al. Interventions for erythropoietin-resistant anaemia in dialysis patients. Cochrane Database Syst Rev. 2013;:CD006861 pubmed publisher
Sienas L, Wong T, Collins R, Smith J. Contemporary uses of erythropoietin in pregnancy: a literature review. Obstet Gynecol Surv. 2013;68:594-602 pubmed publisher
Bartnicki P, Kowalczyk M, Rysz J. The influence of the pleiotropic action of erythropoietin and its derivatives on nephroprotection. Med Sci Monit. 2013;19:599-605 pubmed publisher
Dzgoeva F, Gatagonova T, Kadzaeva Z, Khamitsaeva O, Kochisova Z, Dzueva A, et al. [Diastolic dysfunction in different types of left ventricular hypertrophy in patients with end-stage renal failure: impact of long-term erythropoietin therapy]. Ter Arkh. 2013;85:44-50 pubmed
Dang C, Hudis C, Norton L. Epoetin alfa: to give or not to give. J Natl Cancer Inst. 2013;105:1001-3 pubmed publisher
Leyland Jones B. Erythropoiesis stimulating agents: a personal journey. J Natl Cancer Inst. 2013;105:999-1001 pubmed publisher
Mariotti C, Nachbauer W, Panzeri M, Poewe W, Taroni F, Boesch S. Erythropoietin in Friedreich ataxia. J Neurochem. 2013;126 Suppl 1:80-7 pubmed publisher
Ellis A, Brookhart M. Approaches to inverse-probability-of-treatment--weighted estimation with concurrent treatments. J Clin Epidemiol. 2013;66:S51-6 pubmed publisher
Al Saran K, Sabry A, Hassan A. Effect of relative hypoparathyroidism on the responsiveness to recombinant human erythropoietin in chronic hemodialysis patients: a single Saudi center experience. Saudi J Kidney Dis Transpl. 2013;24:825-31 pubmed
Mastromarino V, Musumeci M, Conti E, Tocci G, Volpe M. Erythropoietin in cardiac disease: effective or harmful?. J Cardiovasc Med (Hagerstown). 2013;14:870-8 pubmed publisher
Bath P, Sprigg N, England T. Colony stimulating factors (including erythropoietin, granulocyte colony stimulating factor and analogues) for stroke. Cochrane Database Syst Rev. 2013;:CD005207 pubmed publisher
Ohls R, Christensen R, Kamath Rayne B, Rosenberg A, Wiedmeier S, Roohi M, et al. A randomized, masked, placebo-controlled study of darbepoetin alfa in preterm infants. Pediatrics. 2013;132:e119-27 pubmed publisher
Wilson R, Dong S, Wang P, Danishefsky S. The winding pathway to erythropoietin along the chemistry-biology frontier: a success at last. Angew Chem Int Ed Engl. 2013;52:7646-65 pubmed publisher
Seibold N, Schild S, Gebhard M, Noack F, Schroder U, Rades D. Prognosis of patients with locally advanced squamous cell carcinoma of the head and neck. Impact of tumor cell expression of EPO and EPO-R. Strahlenther Onkol. 2013;189:559-65 pubmed publisher
Roubille F, Prunier F, Barrère Lemaire S, Leclercq F, Piot C, Kritikou E, et al. What is the role of erythropoietin in acute myocardial infarct? Bridging the gap between experimental models and clinical trials. Cardiovasc Drugs Ther. 2013;27:315-31 pubmed publisher
Zhou M, Chen S, Wang W, Huang W, Cheng B, Ding X, et al. Levels of erythropoietin and vascular endothelial growth factor in surgery-required advanced neovascular glaucoma eyes before and after intravitreal injection of bevacizumab. Invest Ophthalmol Vis Sci. 2013;54:3874-9 pubmed publisher
Tan Q, Kerestes H, Percy M, Pietrofesa R, Chen L, Khurana T, et al. Erythrocytosis and pulmonary hypertension in a mouse model of human HIF2A gain of function mutation. J Biol Chem. 2013;288:17134-44 pubmed publisher
Günter C, Rezaeian F, Harder Y, Lohmeyer J, Egert S, Bader A, et al. [Erythropoietin in plastic surgery]. Handchir Mikrochir Plast Chir. 2013;45:108-19 pubmed publisher
Yeh P, Liao F, Lin S. Is the renoprotective effect of erythropoietin in chronic kidney disease a myth?. J Formos Med Assoc. 2013;112:655-6 pubmed publisher
Chong Z, Shang Y, Mu Y, Cui S, Yao Q, Maiese K. Targeting erythropoietin for chronic neurodegenerative diseases. Expert Opin Ther Targets. 2013;17:707-20 pubmed publisher
Bunn H. Erythropoietin. Cold Spring Harb Perspect Med. 2013;3:a011619 pubmed publisher
Reichel C, Thevis M. Gel electrophoretic methods for the analysis of biosimilar pharmaceuticals using the example of recombinant erythropoietin. Bioanalysis. 2013;5:587-602 pubmed publisher
Broxmeyer H. Erythropoietin: multiple targets, actions, and modifying influences for biological and clinical consideration. J Exp Med. 2013;210:205-8 pubmed publisher
Morais C, Johnson D, Vesey D, Gobe G. Functional significance of erythropoietin in renal cell carcinoma. BMC Cancer. 2013;13:14 pubmed publisher
Lomonosov M, Meziane E, Ye H, Nelson D, Randle S, Laman H. Expression of Fbxo7 in haematopoietic progenitor cells cooperates with p53 loss to promote lymphomagenesis. PLoS ONE. 2011;6:e21165 pubmed publisher
product information
Catalog Number :
H5166
Product Name :
Erythropoietin human
Product Type :
GROWTH FACTORS
Product Group :
Cell Biology
Product Description :
EPO, recombinant, expressed in HEK 293 cells, suitable for cell culture
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA