This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Hyaluronidase from bovine testes
catalog :
H3506
citations: 211
Reference
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Valcarcel J, García M, Varela U, Vazquez J. Hyaluronic acid of tailored molecular weight by enzymatic and acid depolymerization. Int J Biol Macromol. 2020;145:788-794 pubmed publisher
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Xu Y, Xu Y, Zhu Y, Sun H, Juguilon C, Li F, et al. Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis. Mol Ther. 2020;28:202-216 pubmed publisher
Kodali M, Castro O, Kim D, Thomas A, Shuai B, Attaluri S, et al. Intranasally Administered Human MSC-Derived Extracellular Vesicles Pervasively Incorporate into Neurons and Microglia in both Intact and Status Epilepticus Injured Forebrain. Int J Mol Sci. 2019;21: pubmed publisher
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Leech J, Dhariwala M, Lowe M, Chu K, Merana G, Cornuot C, et al. Toxin-Triggered Interleukin-1 Receptor Signaling Enables Early-Life Discrimination of Pathogenic versus Commensal Skin Bacteria. Cell Host Microbe. 2019;26:795-809.e5 pubmed publisher
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Frodermann V, Rohde D, Courties G, Severe N, Schloss M, Amatullah H, et al. Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells. Nat Med. 2019;25:1761-1771 pubmed publisher
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Parameswaran N, Bartel C, Hernandez Sanchez W, Miskimen K, Smigiel J, Khalil A, et al. A FAM83A Positive Feed-back Loop Drives Survival and Tumorigenicity of Pancreatic Ductal Adenocarcinomas. Sci Rep. 2019;9:13396 pubmed publisher
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Hazzan T, Eberle J, Worm M, Babina M. Thymic Stromal Lymphopoietin Interferes with the Apoptosis of Human Skin Mast Cells by a Dual Strategy Involving STAT5/Mcl-1 and JNK/Bcl-xL. Cells. 2019;8: pubmed publisher
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Zerbinati N, Mocchi R, Galadari H, Maccario C, Maggi M, Rauso R, et al. In Vitro Evaluation of the Biological Availability of Hyaluronic Acid Polyethylene Glycols-Cross-Linked Hydrogels to Bovine Testes Hyaluronidase. Biomed Res Int. 2019;2019:3196723 pubmed publisher
Rotgers E, Cisneros Montalvo S, Nurmio M, Toppari J. Retinoblastoma protein represses E2F3 to maintain Sertoli cell quiescence in mouse testis. J Cell Sci. 2019;132: pubmed publisher
Taskin A, Kocabay A, Ebrahimi A, Karahuseyinoglu S, Sahin G, Özçimen B, et al. Leptin treatment of in vitro cultured embryos increases outgrowth rate of inner cell mass during embryonic stem cell derivation. In Vitro Cell Dev Biol Anim. 2019;: pubmed publisher
Remedios K, Meyer L, Zirak B, Pauli M, Truong H, Boda D, et al. CD27 Promotes CD4+ Effector T Cell Survival in Response to Tissue Self-Antigen. J Immunol. 2019;: pubmed publisher
Yu Taeger L, Stricker Shaver J, Arnold K, Bambynek Dziuk P, Novati A, Singer E, et al. Intranasal Administration of Mesenchymal Stem Cells Ameliorates the Abnormal Dopamine Transmission System and Inflammatory Reaction in the R6/2 Mouse Model of Huntington Disease. Cells. 2019;8: pubmed publisher
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Zhao W, Su J, Wang Y, Qian T, Liu Y. Functional importance of palmitoyl protein thioesterase 1 (PPT1) expression by Sertoli cells in mediating cholesterol metabolism and maintenance of sperm quality. Mol Reprod Dev. 2019;86:984-998 pubmed publisher
Schneider C, Lee J, Koga S, Ricardo Gonzalez R, Nussbaum J, Smith L, et al. Tissue-Resident Group 2 Innate Lymphoid Cells Differentiate by Layered Ontogeny and In Situ Perinatal Priming. Immunity. 2019;50:1425-1438.e5 pubmed publisher
Merz S, Korste S, Bornemann L, Michel L, Stock P, Squire A, et al. Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response. Nat Commun. 2019;10:2312 pubmed publisher
Matysik A, Kline K. Streptococcus pyogenes capsule promotes microcolony-independent biofilm formation. J Bacteriol. 2019;: pubmed publisher
Kulaberoglu Y, Bhushan B, Hadi F, Chakrabarti S, Khaled W, Rankin K, et al. The material properties of naked mole-rat hyaluronan. Sci Rep. 2019;9:6632 pubmed publisher
Carter N, Roach Z, Byrnes M, Zhu Y. Adamts9 is necessary for ovarian development in zebrafish. Gen Comp Endocrinol. 2019;277:130-140 pubmed publisher
Silva W, Graca F, Cruz A, Silvestre J, Labeit S, Miyabara E, et al. miR-29c improves skeletal muscle mass and function throughout myocyte proliferation and differentiation and by repressing atrophy-related genes. Acta Physiol (Oxf). 2019;226:e13278 pubmed publisher
Goossens P, Rodriguez Vita J, Etzerodt A, Masse M, Rastoin O, Gouirand V, et al. Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression. Cell Metab. 2019;29:1376-1389.e4 pubmed publisher
Jiménez Torres J, Virumbrales Muñoz M, Sung K, Lee M, Abel E, Beebe D. Patient-specific organotypic blood vessels as an in vitro model for anti-angiogenic drug response testing in renal cell carcinoma. EBioMedicine. 2019;42:408-419 pubmed publisher
Dvoriantchikova G, Seemungal R, Ivanov D. The epigenetic basis for the impaired ability of adult murine retinal pigment epithelium cells to regenerate retinal tissue. Sci Rep. 2019;9:3860 pubmed publisher
Murdoch C, Espenschied S, Matty M, Mueller O, Tobin D, Rawls J. Intestinal Serum amyloid A suppresses systemic neutrophil activation and bactericidal activity in response to microbiota colonization. PLoS Pathog. 2019;15:e1007381 pubmed publisher
Tran H, Mittal A, Sagi V, Luk K, Nguyen A, Gupta M, et al. Mast Cells Induce Blood Brain Barrier Damage in SCD by Causing Endoplasmic Reticulum Stress in the Endothelium. Front Cell Neurosci. 2019;13:56 pubmed publisher
Kojima M, de Rooij D, Page D. Amplification of a broad transcriptional program by a common factor triggers the meiotic cell cycle in mice. elife. 2019;8: pubmed publisher
Zhao J, Wen X, Tian L, Li T, Xu C, Wen X, et al. Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer. Nat Commun. 2019;10:899 pubmed publisher
Hojman P, Brolin C, Nørgaard Christensen N, Dethlefsen C, Lauenborg B, Olsen C, et al. IL-6 release from muscles during exercise is stimulated by lactate-dependent protease activity. Am J Physiol Endocrinol Metab. 2019;316:E940-E947 pubmed publisher
Zhang J, Li H, Wu Q, Chen Y, Deng Y, Yang Z, et al. Tumoral NOX4 recruits M2 tumor-associated macrophages via ROS/PI3K signaling-dependent various cytokine production to promote NSCLC growth. Redox Biol. 2019;22:101116 pubmed publisher
Zhang H, Brown R, Wei Y, Zhao P, Liu S, Liu X, et al. CD44 splice isoform switching determines breast cancer stem cell state. Genes Dev. 2019;33:166-179 pubmed publisher
Keller R, Gunther E. Evolution of Relapse-Proficient Subclones Constrained by Collateral Sensitivity to Oncogene Overdose in Wnt-Driven Mammary Cancer. Cell Rep. 2019;26:893-905.e4 pubmed publisher
Maly K, Schaible I, Riegger J, Brenner R, Meurer A, Zaucke F. The Expression of Thrombospondin-4 Correlates with Disease Severity in Osteoarthritic Knee Cartilage. Int J Mol Sci. 2019;20: pubmed publisher
Hannoun A, Ouenzerfi G, Brizuela L, Mebarek S, Bougault C, Hassler M, et al. Pyrocarbon versus cobalt-chromium in the context of spherical interposition implants: an in vitro study on cultured chondrocytes. Eur Cell Mater. 2019;37:1-15 pubmed publisher
Ullah O, Li Z, Ali I, Xu L, Liu H, Jin H, et al. Pterostilbene exerts a protective effect via regulating tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos. In Vitro Cell Dev Biol Anim. 2019;55:82-93 pubmed publisher
Zhang S, Lei X, Huo P, Liu Q, Guan X, Jiang J, et al. The effects of IAM38 blocking or CD4 blocking on the binding of exogenous DNA in rabbit sperm. Mol Biol Rep. 2019;46:251-259 pubmed publisher
Sun H, Kang J, Su J, Zhang J, Zhang L, Liu X, et al. Methionine adenosyltransferase 2A regulates mouse zygotic genome activation and morula to blastocyst transition†. Biol Reprod. 2019;100:601-617 pubmed publisher
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Leidy Davis T, Cheng K, Goodwin L, Morgan J, Juan W, Roca X, et al. Viable Mice with Extensive Gene Humanization (25-kbp) Created Using Embryonic Stem Cell/Blastocyst and CRISPR/Zygote Injection Approaches. Sci Rep. 2018;8:15028 pubmed publisher
Zhao J, Xiao Z, Li T, Chen H, Yuan Y, Wang Y, et al. Stromal Modulation Reverses Primary Resistance to Immune Checkpoint Blockade in Pancreatic Cancer. ACS Nano. 2018;12:9881-9893 pubmed publisher
Weston C, Rana B, Cousins D. Differential expression of functional chemokine receptors on human blood and lung group 2 innate lymphoid cells (ILC2s). J Allergy Clin Immunol. 2018;: pubmed publisher
Long K, Newland B, Florio M, Kalebic N, Langen B, Kolterer A, et al. Extracellular Matrix Components HAPLN1, Lumican, and Collagen I Cause Hyaluronic Acid-Dependent Folding of the Developing Human Neocortex. Neuron. 2018;99:702-719.e6 pubmed publisher
Pavel M, Renna M, Park S, Menzies F, Ricketts T, Füllgrabe J, et al. Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis. Nat Commun. 2018;9:2961 pubmed publisher
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Sizemore G, Balakrishnan S, Thies K, Hammer A, Sizemore S, TRIMBOLI A, et al. Stromal PTEN determines mammary epithelial response to radiotherapy. Nat Commun. 2018;9:2783 pubmed publisher
Lamas Toranzo I, Pericuesta E, Bermejo Alvarez P. Mitochondrial and metabolic adjustments during the final phase of follicular development prior to IVM of bovine oocytes. Theriogenology. 2018;119:156-162 pubmed publisher
Michea P, Noël F, Zakine E, Czerwinska U, Sirven P, Abouzid O, et al. Adjustment of dendritic cells to the breast-cancer microenvironment is subset specific. Nat Immunol. 2018;19:885-897 pubmed publisher
Li X, Cao P, Han W, Xu Y, Wu H, Yu X, et al. Non-invasive metabolomic profiling of culture media of ICSI- and IVF-derived early developmental cattle embryos via Raman spectroscopy. Anim Reprod Sci. 2018;196:99-110 pubmed publisher
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Tang J, Frey J, Wilson C, Moncada Pazos A, Levet C, Freeman M, et al. Neutrophil and Macrophage Cell Surface Colony-Stimulating Factor 1 Shed by ADAM17 Drives Mouse Macrophage Proliferation in Acute and Chronic Inflammation. Mol Cell Biol. 2018;38: pubmed publisher
Jo S, Wang S, Lee Y, Kang S, Lee B, Han J, et al. IL-17A induces osteoblast differentiation by activating JAK2/STAT3 in ankylosing spondylitis. Arthritis Res Ther. 2018;20:115 pubmed publisher
Canovas B, Igea A, Sartori A, Gomis R, Paull T, Isoda M, et al. Targeting p38α Increases DNA Damage, Chromosome Instability, and the Anti-tumoral Response to Taxanes in Breast Cancer Cells. Cancer Cell. 2018;33:1094-1110.e8 pubmed publisher
Lilja A, Rodilla V, Huyghe M, Hannezo E, Landragin C, Renaud O, et al. Clonal analysis of Notch1-expressing cells reveals the existence of unipotent stem cells that retain long-term plasticity in the embryonic mammary gland. Nat Cell Biol. 2018;20:677-687 pubmed publisher
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Brett M, Bomberger H, Doak G, Price M, McCarthy J, Wood D. In vitro elucidation of the role of pericellular matrix in metastatic extravasation and invasion of breast carcinoma cells. Integr Biol (Camb). 2018;10:242-252 pubmed publisher
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Tawiah A, Cornick S, Moreau F, Gorman H, Kumar M, Tiwari S, et al. High MUC2 Mucin Expression and Misfolding Induce Cellular Stress, Reactive Oxygen Production, and Apoptosis in Goblet Cells. Am J Pathol. 2018;188:1354-1373 pubmed publisher
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Raposo B, Merky P, Lundqvist C, Yamada H, Urbonaviciute V, Niaudet C, et al. T cells specific for post-translational modifications escape intrathymic tolerance induction. Nat Commun. 2018;9:353 pubmed publisher
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Roof S, Ueyama Y, Mazhari R, Hamlin R, Hartman J, Ziolo M, et al. CXL-1020, a Novel Nitroxyl (HNO) Prodrug, Is More Effective than Milrinone in Models of Diastolic Dysfunction-A Cardiovascular Therapeutic: An Efficacy and Safety Study in the Rat. Front Physiol. 2017;8:894 pubmed publisher
Chamberlin T, D Amato J, Arendt L. Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity. Breast Cancer Res. 2017;19:128 pubmed publisher
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Flowers S, Zieba A, Örnros J, Jin C, Rolfson O, Björkman L, et al. Lubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface. Sci Rep. 2017;7:13149 pubmed publisher
Nagao M, Hamilton J, Kc R, Berendsen A, Duan X, Cheong C, et al. Vascular Endothelial Growth Factor in Cartilage Development and Osteoarthritis. Sci Rep. 2017;7:13027 pubmed publisher
Chen D, Li X, Liu X, Liu X, Jiang X, Du J, et al. NQO2 inhibition relieves reactive oxygen species effects on mouse oocyte meiotic maturation and embryo development. Biol Reprod. 2017;97:598-611 pubmed publisher
Ozil J, Sainte Beuve T, Banrezes B. [Mg2+]o/[Ca2+]o determines Ca2+ response at fertilization: tuning of adult phenotype?. Reproduction. 2017;154:675-693 pubmed publisher
Nieminen H, Barreto G, Finnilä M, Garcia Perez A, Salmi A, Ranjan S, et al. Laser-ultrasonic delivery of agents into articular cartilage. Sci Rep. 2017;7:3991 pubmed publisher
Kim H, Lee E, An Y, Kim S, Lee S, Yu S, et al. Chondroitin Sulfate-Based Biomineralizing Surface Hydrogels for Bone Tissue Engineering. ACS Appl Mater Interfaces. 2017;9:21639-21650 pubmed publisher
Panda B, Pandey S, Somal A, Parmar M, Bhat I, Baiju I, et al. Leptin supplementation in vitro improved developmental competence of buffalo oocytes and embryos. Theriogenology. 2017;98:116-122 pubmed publisher
Sergin I, Evans T, Zhang X, Bhattacharya S, Stokes C, Song E, et al. Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis. Nat Commun. 2017;8:15750 pubmed publisher
Xu Y, Zhou T, Shao L, Zhang B, Liu K, Gao C, et al. Gene expression profiles in mouse cumulus cells derived from in vitro matured oocytes with and without blastocyst formation. Gene Expr Patterns. 2017;25-26:46-58 pubmed publisher
Chanrot M, Blomqvist G, Guo Y, Ullman K, Juremalm M, Båge R, et al. Bovine herpes virus type 4 alters TNF-? and IL-8 profiles and impairs the survival of bovine endometrial epithelial cells. Reprod Biol. 2017;17:225-232 pubmed publisher
Liu S, Cheng C. Akt Signaling Is Sustained by a CD44 Splice Isoform-Mediated Positive Feedback Loop. Cancer Res. 2017;77:3791-3801 pubmed publisher
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Reda A, Albalushi H, Montalvo S, Nurmio M, Sahin Z, Hou M, et al. Knock-Out Serum Replacement and Melatonin Effects on Germ Cell Differentiation in Murine Testicular Explant Cultures. Ann Biomed Eng. 2017;45:1783-1794 pubmed publisher
Richardson S, Ludwinski F, Gnanalingham K, Atkinson R, Freemont A, Hoyland J. Notochordal and nucleus pulposus marker expression is maintained by sub-populations of adult human nucleus pulposus cells through aging and degeneration. Sci Rep. 2017;7:1501 pubmed publisher
Syed Khaja A, Toor S, El Salhat H, Faour I, Ul Haq N, Ali B, et al. Preferential accumulation of regulatory T cells with highly immunosuppressive characteristics in breast tumor microenvironment. Oncotarget. 2017;8:33159-33171 pubmed publisher
Sarper M, Allen M, Gomm J, Haywood L, Decock J, Thirkettle S, et al. Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function. Breast Cancer Res. 2017;19:33 pubmed publisher
Cimini D, Iacono I, Carlino E, Finamore R, Restaino O, Diana P, et al. Engineering S. equi subsp. zooepidemicus towards concurrent production of hyaluronic acid and chondroitin biopolymers of biomedical interest. AMB Express. 2017;7:61 pubmed publisher
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Basak F, Atalgin S, Bozkurt E. Tongue and lingual salivary glands of the canary: scanning electron microscopy and histochemical study. Folia Morphol (Warsz). 2017;76:348-354 pubmed publisher
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Laurent R, Nallet A, de Billy B, Obert L, Nicod L, Meyer C, et al. Fresh and in vitro osteodifferentiated human amniotic membrane, alone or associated with an additional scaffold, does not induce ectopic bone formation in Balb/c mice. Cell Tissue Bank. 2017;18:17-25 pubmed publisher
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Chanrot M, Guo Y, Dalin A, Persson E, Båge R, Svensson A, et al. Dose related effects of LPS on endometrial epithelial cell populations from dioestrus cows. Anim Reprod Sci. 2017;177:12-24 pubmed publisher
Higaki S, Kishi M, Koyama K, Nagano M, Katagiri S, Takada T, et al. Early germinal vesicle breakdown is a predictor of high preimplantation developmental competent oocytes in mice. Zygote. 2017;25:41-48 pubmed publisher
López Cardona A, Sánchez Calabuig M, Beltrán Breña P, Agirregoitia N, Rizos D, Agirregoitia E, et al. Exocannabinoids effect on in vitro bovine oocyte maturation via activation of AKT and ERK1/2. Reproduction. 2016;152:603-612 pubmed
van Haaften E, Ito K, van Donkelaar C. The initial repair response of articular cartilage after mechanically induced damage. J Orthop Res. 2017;35:1265-1273 pubmed publisher
Mattson J, Turcotte R, Zhang Y. Glycosaminoglycans contribute to extracellular matrix fiber recruitment and arterial wall mechanics. Biomech Model Mechanobiol. 2017;16:213-225 pubmed publisher
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Xu Z, Song Z, Li G, Tu H, Liu W, Liu Y, et al. H2B ubiquitination regulates meiotic recombination by promoting chromatin relaxation. Nucleic Acids Res. 2016;44:9681-9697 pubmed
Islam A, Hansen A, Mennan C, Martínez Zubiaurre I. Mesenchymal stromal cells from human umbilical cords display poor chondrogenic potential in scaffold-free three dimensional cultures. Eur Cell Mater. 2016;31:407-24 pubmed
Li L, Grausam K, Wang J, Lun M, Ohli J, Lidov H, et al. Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells. Nat Cell Biol. 2016;18:418-30 pubmed publisher
Li B, Singer N, Yeni Y, Haggins D, Barnboym E, Oravec D, et al. A Point-of-Care Raman Spectroscopy-Based Device for the Diagnosis of Gout and Pseudogout: Comparison With the Clinical Standard Microscopy. Arthritis Rheumatol. 2016;68:1751-7 pubmed publisher
Zhu Z, Li C, Yang S, Tian R, Wang J, Yuan Q, et al. Dynamics of the Transcriptome during Human Spermatogenesis: Predicting the Potential Key Genes Regulating Male Gametes Generation. Sci Rep. 2016;6:19069 pubmed publisher
Amano K, Densmore M, Fan Y, Lanske B. Ihh and PTH1R signaling in limb mesenchyme is required for proper segmentation and subsequent formation and growth of digit bones. Bone. 2016;83:256-266 pubmed publisher
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product information
Catalog Number :
H3506
Product Name :
Hyaluronidase from bovine testes
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
Type I-S, lyophilized powder, 400-1000 units/mg solid
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA