This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
DL-threo-β-Hydroxyaspartic acid
catalog :
H2775
citations: 30
Reference |
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Naganska E, Taraszewska A, Matyja E, Grieb P, Rafałowska J. Neuroprotective effect of erythropoietin in amyotrophic lateral sclerosis (ALS) model in vitro. Ultrastructural study. Folia Neuropathol. 2010;48:35-44 pubmed
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Borisova T, Kasatkina L. Glutamate transporters of blood platelets as potential peripheral markers to analyze changes of glutamate transport activity in brain under altered gravity conditions. J Gravit Physiol. 2007;14:P81-2 pubmed
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Hemendinger R, Armstrong E, Persinski R, Todd J, Mougeot J, Volvovitz F, et al. Huperzine A provides neuroprotection against several cell death inducers using in vitro model systems of motor neuron cell death. Neurotox Res. 2008;13:49-61 pubmed
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Bonomo J, Lynch M, Warnecke T, Price J, Gill R. Genome-scale analysis of anti-metabolite directed strain engineering. Metab Eng. 2008;10:109-20 pubmed
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Khalaf J, Datta A. A concise, asymmetric synthesis of (2R,3R)-3-hydroxyaspartic acid. Amino Acids. 2008;35:507-10 pubmed
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Myint A, Kim Y, Verkerk R, Park S, Scharpe S, Steinbusch H, et al. Tryptophan breakdown pathway in bipolar mania. J Affect Disord. 2007;102:65-72 pubmed
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Borisova T, Krysanova N, Himmelreich N. [Modulating effect of glutamate transporter inhibitors on accumulation and release of the neuromediator by the brain nerve terminals in rats]. Ukr Biokhim Zh (1999). 2005;77:61-7 pubmed
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Matyja E, Taraszewska A, Naganska E, Rafałowska J. Autophagic degeneration of motor neurons in a model of slow glutamate excitotoxicity in vitro. Ultrastruct Pathol. 2005;29:331-9 pubmed
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Borisova T, Himmelreich N. Effects of the inhibitors on glutamate uptake by nerve terminals after exposure of rats to centrifuge-induced hypergravity. J Gravit Physiol. 2004;11:P37-8 pubmed
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Meera P, Dodson P, Karakossian M, Otis T. Expression of GFP-tagged neuronal glutamate transporters in cerebellar Purkinje neurons. Neuropharmacology. 2005;49:883-9 pubmed
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Darman J, Backovic S, Dike S, Maragakis N, Krishnan C, Rothstein J, et al. Viral-induced spinal motor neuron death is non-cell-autonomous and involves glutamate excitotoxicity. J Neurosci. 2004;24:7566-75 pubmed
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Lozovaya N, Melnik S, Tsintsadze T, Grebenyuk S, Kirichok Y, Krishtal O. Protective cap over CA1 synapses: extrasynaptic glutamate does not reach the postsynaptic density. Brain Res. 2004;1011:195-205 pubmed
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Wang Z, Li W, Mitchell C, Carter Dawson L. Activation of protein kinase C reduces GLAST in the plasma membrane of rat Müller cells in primary culture. Vis Neurosci. 2003;20:611-9 pubmed
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Hu J, Yang N, Ma Y, Jiang J, Zhang J, Fei J, et al. Identification of glutamate transporters and receptors in mouse testis. Acta Pharmacol Sin. 2004;25:366-71 pubmed
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Zhang H, Sulzer D. Glutamate spillover in the striatum depresses dopaminergic transmission by activating group I metabotropic glutamate receptors. J Neurosci. 2003;23:10585-92 pubmed
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Wada M, Nakamori S, Takagi H. Serine racemase homologue of Saccharomyces cerevisiae has L-threo-3-hydroxyaspartate dehydratase activity. FEMS Microbiol Lett. 2003;225:189-93 pubmed
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Kidd F, Isaac J. Glutamate transport blockade has a differential effect on AMPA and NMDA receptor-mediated synaptic transmission in the developing barrel cortex. Neuropharmacology. 2000;39:725-32 pubmed
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Shimamoto K, Lebrun B, Yasuda Kamatani Y, Sakaitani M, Shigeri Y, Yumoto N, et al. DL-threo-beta-benzyloxyaspartate, a potent blocker of excitatory amino acid transporters. Mol Pharmacol. 1998;53:195-201 pubmed
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Hirata A, Nakamura R, Kwak S, Nagata N, Kamakura K. AMPA receptor-mediated slow neuronal death in the rat spinal cord induced by long-term blockade of glutamate transporters with THA. Brain Res. 1997;771:37-44 pubmed
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Klegeris A, Walker D, McGeer P. Regulation of glutamate in cultures of human monocytic THP-1 and astrocytoma U-373 MG cells. J Neuroimmunol. 1997;78:152-61 pubmed
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product information
Catalog Number :
H2775
Product Name :
DL-threo-β-Hydroxyaspartic acid
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
company information

MilliporeSigma
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