Thomas R, Henson A, Gerrish A, Jones L, Williams J, Kidd E. Decreasing the expression of PICALM reduces endocytosis and the activity of β-secretase: implications for Alzheimer's disease. BMC Neurosci. 2016;17:50 pubmed publisher

Winter L, Wittig I, Peeva V, Eggers B, Heidler J, Chevessier F, et al. Mutant desmin substantially perturbs mitochondrial morphology, function and maintenance in skeletal muscle tissue. Acta Neuropathol. 2016;132:453-73 pubmed publisher

Fusté N, Fernández Hernández R, Cemeli T, Mirantes C, Pedraza N, Rafel M, et al. Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin. Nat Commun. 2016;7:11581 pubmed publisher

Zhang Y, Liu J, Lin J, Zhou L, Song Y, Wei B, et al. The transcription factor GATA1 and the histone methyltransferase SET7 interact to promote VEGF-mediated angiogenesis and tumor growth and predict clinical outcome of breast cancer. Oncotarget. 2016;7:9859-75 pubmed publisher

Jiang C, Fang X, Jiang Y, Shen F, Hu Z, Li X, et al. TNF-α induces vascular endothelial cells apoptosis through overexpressing pregnancy induced noncoding RNA in Kawasaki disease model. Int J Biochem Cell Biol. 2016;72:118-124 pubmed publisher

Zhou H, Wang T, Zheng T, Teng J, Chen J. Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2. Nat Commun. 2016;7:10151 pubmed publisher

Klacz J, Wierzbicki P, Wronska A, Rybarczyk A, Stanislawowski M, Slebioda T, et al. Decreased expression of RASSF1A tumor suppressor gene is associated with worse prognosis in clear cell renal cell carcinoma. Int J Oncol. 2016;48:55-66 pubmed publisher

Rastetter R, Blömacher M, Drebber U, Marko M, Behrens J, Solga R, et al. Coronin 2A (CRN5) expression is associated with colorectal adenoma-adenocarcinoma sequence and oncogenic signalling. BMC Cancer. 2015;15:638 pubmed publisher

Thatcher S, Zhang X, Woody S, Wang Y, Alsiraj Y, Charnigo R, et al. Exogenous 17-β estradiol administration blunts progression of established angiotensin II-induced abdominal aortic aneurysms in female ovariectomized mice. Biol Sex Differ. 2015;6:12 pubmed publisher

Nasipak B, Padilla Benavides T, Green K, Leszyk J, Mao W, Konda S, et al. Opposing calcium-dependent signalling pathways control skeletal muscle differentiation by regulating a chromatin remodelling enzyme. Nat Commun. 2015;6:7441 pubmed publisher

Padilla Benavides T, Nasipak B, Imbalzano A. Brg1 Controls the Expression of Pax7 to Promote Viability and Proliferation of Mouse Primary Myoblasts. J Cell Physiol. 2015;230:2990-7 pubmed publisher

Ghatak S, Chan Y, Khanna S, Banerjee J, Weist J, Roy S, et al. Barrier Function of the Repaired Skin Is Disrupted Following Arrest of Dicer in Keratinocytes. Mol Ther. 2015;23:1201-1210 pubmed publisher

Kondapalli K, Llongueras J, Capilla González V, Prasad H, Hack A, Smith C, et al. A leak pathway for luminal protons in endosomes drives oncogenic signalling in glioblastoma. Nat Commun. 2015;6:6289 pubmed publisher

Lu S, Zeumer L, Sorensen H, Yang H, Ng Y, Yu F, et al. The murine Pbx1-d lupus susceptibility allele accelerates mesenchymal stem cell differentiation and impairs their immunosuppressive function. J Immunol. 2015;194:43-55 pubmed

Rochman M, Kartashov A, Caldwell J, Collins M, Stucke E, Kc K, et al. Neurotrophic tyrosine kinase receptor 1 is a direct transcriptional and epigenetic target of IL-13 involved in allergic inflammation. Mucosal Immunol. 2015;8:785-98 pubmed publisher

Haug S, Schnerch D, Halbach S, Mastroianni J, Dumit V, Follo M, et al. Metadherin exon 11 skipping variant enhances metastatic spread of ovarian cancer. Int J Cancer. 2015;136:2328-40 pubmed publisher

Song J, An N, Chatterjee S, Kistner Griffin E, Mahajan S, Mehrotra S, et al. Deletion of Pim kinases elevates the cellular levels of reactive oxygen species and sensitizes to K-Ras-induced cell killing. Oncogene. 2015;34:3728-36 pubmed publisher

Wang Y, Zaitsev K, Lu Q, Li S, Schaiff W, Kim K, et al. Select autophagy genes maintain quiescence of tissue-resident macrophages and increase susceptibility to Listeria monocytogenes. Nat Microbiol. 2020;5:272-281 pubmed publisher

Shao L, Liu Y, Wang W, Li A, Wan P, Liu W, et al. SUMO1 SUMOylates and SENP3 deSUMOylates NLRP3 to orchestrate the inflammasome activation. FASEB J. 2020;34:1497-1515 pubmed publisher

Bhatta A, Atianand M, Jiang Z, Crabtree J, Blin J, Fitzgerald K. A Mitochondrial Micropeptide Is Required for Activation of the Nlrp3 Inflammasome. J Immunol. 2020;204:428-437 pubmed publisher

Zhang B, Chan T, Tam P, Liu Y, Pang C, Jhanji V, et al. A Cohesin Subunit Variant Identified from a Peripheral Sclerocornea Pedigree. Dis Markers. 2019;2019:8781524 pubmed publisher

Zhao W, Li H, Yang S, Guo D, Chen J, Miao S, et al. MicroRNA-152 suppresses cisplatin resistance in A549 cells. Oncol Lett. 2019;18:4613-4620 pubmed publisher

Zhou H, Zheng T, Wang T, Li Q, Wang F, Liang X, et al. CCDC74A/B are K-fiber crosslinkers required for chromosomal alignment. BMC Biol. 2019;17:73 pubmed publisher

Wang X, Sommerfeld M, Jahn Hofmann K, Cai B, Filliol A, Remotti H, et al. A Therapeutic Silencing RNA Targeting Hepatocyte TAZ Prevents and Reverses Fibrosis in Nonalcoholic Steatohepatitis in Mice. Hepatol Commun. 2019;3:1221-1234 pubmed publisher

Hao Y, Fan X, Shi Y, Zhang C, Sun D, Qin K, et al. Next-generation unnatural monosaccharides reveal that ESRRB O-GlcNAcylation regulates pluripotency of mouse embryonic stem cells. Nat Commun. 2019;10:4065 pubmed publisher

Ziliotto S, Gee J, Ellis I, Green A, Finlay P, Gobbato A, et al. Activated zinc transporter ZIP7 as an indicator of anti-hormone resistance in breast cancer. Metallomics. 2019;11:1579-1592 pubmed publisher

Singh A, Manjunath L, Kundu P, Sahoo S, Das A, Suma H, et al. Let-7a-regulated translational readthrough of mammalian AGO1 generates a microRNA pathway inhibitor. EMBO J. 2019;38:e100727 pubmed publisher

Witwicka H, Nogami J, Syed S, Maehara K, Padilla Benavides T, Ohkawa Y, et al. Calcineurin Broadly Regulates the Initiation of Skeletal Muscle-Specific Gene Expression by Binding Target Promoters and Facilitating the Interaction of the SWI/SNF Chromatin Remodeling Enzyme. Mol Cell Biol. 2019;39: pubmed publisher

Sun J, Zhou C, Ma Q, Chen W, Atyah M, Yin Y, et al. High GCLC level in tumor tissues is associated with poor prognosis of hepatocellular carcinoma after curative resection. J Cancer. 2019;10:3333-3343 pubmed publisher

Wierzbicki P, Klacz J, Kotulak Chrzaszcz A, Wronska A, Stanislawowski M, Rybarczyk A, et al. Prognostic significance of VHL, HIF1A, HIF2A, VEGFA and p53 expression in patients with clear‑cell renal cell carcinoma treated with sunitinib as first‑line treatment. Int J Oncol. 2019;55:371-390 pubmed publisher

Wiel C, Le Gal K, Ibrahim M, Jahangir C, Kashif M, Yao H, et al. BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis. Cell. 2019;: pubmed publisher

Huang X, Kuang S, Applegate T, Lin T, Cheng H. The development of the serotonergic and dopaminergic systems during chicken mid-late embryogenesis. Mol Cell Endocrinol. 2019;:110472 pubmed publisher

Dang D, Makena M, Llongueras J, Prasad H, Ko M, Bandral M, et al. A Ca2+-ATPase Regulates E-cadherin Biogenesis and Epithelial-Mesenchymal Transition in Breast Cancer Cells. Mol Cancer Res. 2019;: pubmed publisher

Ghosh M, Lo R, Ivic I, Aguilera B, Qendro V, Devarakonda C, et al. CD13 tethers the IQGAP1-ARF6-EFA6 complex to the plasma membrane to promote ARF6 activation, β1 integrin recycling, and cell migration. Sci Signal. 2019;12: pubmed publisher

He Y, Li S, Tang D, Peng Y, Meng J, Peng S, et al. Circulating Peroxiredoxin-1 is a novel damage-associated molecular pattern and aggravates acute liver injury via promoting inflammation. Free Radic Biol Med. 2019;137:24-36 pubmed publisher

Rawlings N, Lee L, Nakamura Y, Wilkinson K, Henley J. Protective role of the deSUMOylating enzyme SENP3 in myocardial ischemia-reperfusion injury. PLoS ONE. 2019;14:e0213331 pubmed publisher

Woeste M, Stern S, Raju D, Grahn E, Dittmann D, Gutbrod K, et al. Species-specific differences in nonlysosomal glucosylceramidase GBA2 function underlie locomotor dysfunction arising from loss-of-function mutations. J Biol Chem. 2019;294:3853-3871 pubmed publisher

Mastroianni J, Stickel N, Andrlova H, Hanke K, Melchinger W, Duquesne S, et al. miR-146a Controls Immune Response in the Melanoma Microenvironment. Cancer Res. 2019;79:183-195 pubmed publisher

Wu X, Zhang L, Miao Y, Yang J, Wang X, Wang C, et al. Homocysteine causes vascular endothelial dysfunction by disrupting endoplasmic reticulum redox homeostasis. Redox Biol. 2019;20:46-59 pubmed publisher

Sielicka A, Sarin E, Shi W, Sulejmani F, Corporan D, Kalra K, et al. Pathological Remodeling of Mitral Valve Leaflets from Unphysiologic Leaflet Mechanics after Undersized Mitral Annuloplasty to Repair Ischemic Mitral Regurgitation. J Am Heart Assoc. 2018;7:e009777 pubmed publisher

Bjune K, Wierød L, Naderi S. Triciribine increases LDLR expression and LDL uptake through stabilization of LDLR mRNA. Sci Rep. 2018;8:16174 pubmed publisher

Abdelfattah N, Rajamanickam S, Panneerdoss S, Timilsina S, Yadav P, Onyeagucha B, et al. MiR-584-5p potentiates vincristine and radiation response by inducing spindle defects and DNA damage in medulloblastoma. Nat Commun. 2018;9:4541 pubmed publisher

Caravia X, Fanjul V, Oliver E, Roiz Valle D, Morán Álvarez A, Desdín Micó G, et al. The microRNA-29/PGC1α regulatory axis is critical for metabolic control of cardiac function. PLoS Biol. 2018;16:e2006247 pubmed publisher

Panneerdoss S, Eedunuri V, Yadav P, Timilsina S, Rajamanickam S, Viswanadhapalli S, et al. Cross-talk among writers, readers, and erasers of m6A regulates cancer growth and progression. Sci Adv. 2018;4:eaar8263 pubmed publisher

Klymenko Y, Wates R, Weiss Bilka H, Lombard R, Liu Y, Campbell L, et al. Modeling the effect of ascites-induced compression on ovarian cancer multicellular aggregates. Dis Model Mech. 2018;11: pubmed publisher

Fu Y, Long M, Wisitpitthaya S, Inayat H, Pierpont T, Elsaid I, et al. Nuclear RNR-α antagonizes cell proliferation by directly inhibiting ZRANB3. Nat Chem Biol. 2018;14:943-954 pubmed publisher

Hennings T, Chopra D, DeLeon E, VanDeusen H, Sesaki H, Merrins M, et al. In Vivo Deletion of β-Cell Drp1 Impairs Insulin Secretion Without Affecting Islet Oxygen Consumption. Endocrinology. 2018;159:3245-3256 pubmed publisher

Bjune K, Sundvold H, Leren T, Naderi S. MK-2206, an allosteric inhibitor of AKT, stimulates LDLR expression and LDL uptake: A potential hypocholesterolemic agent. Atherosclerosis. 2018;276:28-38 pubmed publisher

Jokl E, Hughes G, Cracknell T, Pownall M, Blanco G. Transcriptional upregulation of Bag3, a chaperone-assisted selective autophagy factor, in animal models of KY-deficient hereditary myopathy. Dis Model Mech. 2018;11: pubmed publisher

Frey Jakobs S, Hartberger J, Fliegauf M, Bossen C, Wehmeyer M, Neubauer J, et al. ZNF341 controls STAT3 expression and thereby immunocompetence. Sci Immunol. 2018;3: pubmed publisher

Zhou C, Chen W, Sun J, Atyah M, Yin Y, Zhang W, et al. Low expression of WW domain-containing oxidoreductase associates with hepatocellular carcinoma aggressiveness and recurrence after curative resection. Cancer Med. 2018;: pubmed publisher

Perrotta C, Cervia D, Di Renzo I, Moscheni C, Bassi M, Campana L, et al. Nitric Oxide Generated by Tumor-Associated Macrophages Is Responsible for Cancer Resistance to Cisplatin and Correlated With Syntaxin 4 and Acid Sphingomyelinase Inhibition. Front Immunol. 2018;9:1186 pubmed publisher

Marwick J, Mills R, Kay O, Michail K, Stephen J, Rossi A, et al. Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-κB activation. Cell Death Dis. 2018;9:665 pubmed publisher

Xing J, Zhang A, Minze L, Li X, Zhang Z. TRIM29 Negatively Regulates the Type I IFN Production in Response to RNA Virus. J Immunol. 2018;201:183-192 pubmed publisher

Fang J, Yang J, Wu X, Zhang G, Li T, Wang X, et al. Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7. Aging Cell. 2018;17:e12765 pubmed publisher

Hernandez C, Huebener P, Pradere J, Antoine D, Friedman R, Schwabe R. HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis. J Clin Invest. 2018;128:2436-2451 pubmed publisher

Melling G, Flannery S, Abidin S, Clemmens H, Prajapati P, Hinsley E, et al. A miRNA-145/TGF-β1 negative feedback loop regulates the cancer-associated fibroblast phenotype. Carcinogenesis. 2018;39:798-807 pubmed publisher

Hu Z, Shi Z, Guo X, Jiang B, Wang G, Luo D, et al. Ligase IV inhibitor SCR7 enhances gene editing directed by CRISPR-Cas9 and ssODN in human cancer cells. Cell Biosci. 2018;8:12 pubmed publisher

Li L, Liang Y, Kang L, Liu Y, Gao S, Chen S, et al. Transcriptional Regulation of the Warburg Effect in Cancer by SIX1. Cancer Cell. 2018;33:368-385.e7 pubmed publisher

Manda Handzlik A, Bystrzycka W, Wachowska M, Sieczkowska S, Stelmaszczyk Emmel A, Demkow U, et al. The influence of agents differentiating HL-60 cells toward granulocyte-like cells on their ability to release neutrophil extracellular traps. Immunol Cell Biol. 2018;96:413-425 pubmed publisher

Halon Golabek M, Borkowska A, Kaczor J, Ziolkowski W, Flis D, Knap N, et al. hmSOD1 gene mutation-induced disturbance in iron metabolism is mediated by impairment of Akt signalling pathway. J Cachexia Sarcopenia Muscle. 2018;9:557-569 pubmed publisher

Chang Z, Lorenzini M, Chen X, Tran U, Bangayan N, Chen Y. Rewiring T-cell responses to soluble factors with chimeric antigen receptors. Nat Chem Biol. 2018;14:317-324 pubmed publisher

Chukwurah E, Patel R. Stress-induced TRBP phosphorylation enhances its interaction with PKR to regulate cellular survival. Sci Rep. 2018;8:1020 pubmed publisher

Vest K, Paskavitz A, Lee J, Padilla Benavides T. Dynamic changes in copper homeostasis and post-transcriptional regulation of Atp7a during myogenic differentiation. Metallomics. 2018;10:309-322 pubmed publisher

Chockley P, Chen J, Chen G, Beer D, Standiford T, Keshamouni V. Epithelial-mesenchymal transition leads to NK cell-mediated metastasis-specific immunosurveillance in lung cancer. J Clin Invest. 2018;128:1384-1396 pubmed publisher

Wang W, Li G, De Wu -, Luo Z, Pan P, Tian M, et al. Zika virus infection induces host inflammatory responses by facilitating NLRP3 inflammasome assembly and interleukin-1β secretion. Nat Commun. 2018;9:106 pubmed publisher

Colicino E, Garrastegui A, Freshour J, Santra P, Post D, Kotula L, et al. Gravin regulates centrosome function through PLK1. Mol Biol Cell. 2018;29:532-541 pubmed publisher

Tomar S, Plotnik J, Haley J, Scantland J, Dasari S, Sheikh Z, et al. ETS1 induction by the microenvironment promotes ovarian cancer metastasis through focal adhesion kinase. Cancer Lett. 2018;414:190-204 pubmed publisher

da Silva Gonçalves Bós D, van der Bruggen C, Kurakula K, Sun X, Casali K, Casali A, et al. Contribution of Impaired Parasympathetic Activity to Right Ventricular Dysfunction and Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension. Circulation. 2018;137:910-924 pubmed publisher

Xing J, Zhang A, Zhang H, Wang J, Li X, Zeng M, et al. TRIM29 promotes DNA virus infections by inhibiting innate immune response. Nat Commun. 2017;8:945 pubmed publisher

Kerasioti E, Terzopoulou Z, Komini O, Kafantaris I, Makri S, Stagos D, et al. Tissue specific effects of feeds supplemented with grape pomace or olive oil mill wastewater on detoxification enzymes in sheep. Toxicol Rep. 2017;4:364-372 pubmed publisher

Padilla Benavides T, Nasipak B, Paskavitz A, Haokip D, Schnabl J, Nickerson J, et al. Casein kinase 2-mediated phosphorylation of Brahma-related gene 1 controls myoblast proliferation and contributes to SWI/SNF complex composition. J Biol Chem. 2017;292:18592-18607 pubmed publisher

Ghosh S, Wallerath C, Covarrubias S, Hornung V, Carpenter S, Fitzgerald K. The PYHIN Protein p205 Regulates the Inflammasome by Controlling Asc Expression. J Immunol. 2017;199:3249-3260 pubmed publisher

Panneerdoss S, Viswanadhapalli S, Abdelfattah N, Onyeagucha B, Timilsina S, Mohammad T, et al. Cross-talk between miR-471-5p and autophagy component proteins regulates LC3-associated phagocytosis (LAP) of apoptotic germ cells. Nat Commun. 2017;8:598 pubmed publisher

Lawson A, Bak D, Shannon D, Long M, Vijaykumar T, Yu R, et al. Identification of deubiquitinase targets of isothiocyanates using SILAC-assisted quantitative mass spectrometry. Oncotarget. 2017;8:51296-51316 pubmed publisher

Kishor A, White E, Matsangos A, Yan Z, Tandukar B, Wilson G. Hsp70's RNA-binding and mRNA-stabilizing activities are independent of its protein chaperone functions. J Biol Chem. 2017;292:14122-14133 pubmed publisher

Zhang J, Min R, Le K, Zhou S, Aghajan M, Than T, et al. The role of MAP2 kinases and p38 kinase in acute murine liver injury models. Cell Death Dis. 2017;8:e2903 pubmed publisher

Dang D, Prasad H, Rao R. Secretory pathway Ca2+ -ATPases promote in vitro microcalcifications in breast cancer cells. Mol Carcinog. 2017;56:2474-2485 pubmed publisher

Klymenko Y, Johnson J, Bos B, Lombard R, Campbell L, Loughran E, et al. Heterogeneous Cadherin Expression and Multicellular Aggregate Dynamics in Ovarian Cancer Dissemination. Neoplasia. 2017;19:549-563 pubmed publisher

Szobi A, Goncalvesova E, Varga Z, Leszek P, Kusmierczyk M, Hulman M, et al. Analysis of necroptotic proteins in failing human hearts. J Transl Med. 2017;15:86 pubmed publisher

Kitada K, Daub S, Zhang Y, Klein J, Nakano D, Pedchenko T, et al. High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation. J Clin Invest. 2017;127:1944-1959 pubmed publisher

Kato K, Mukudai Y, Motohashi H, Ito C, Kamoshida S, Shimane T, et al. Opposite effects of tumor protein D (TPD) 52 and TPD54 on oral squamous cell carcinoma cells. Int J Oncol. 2017;50:1634-1646 pubmed publisher

Xu X, Fan Z, Liang C, Li L, Wang L, Liang Y, et al. A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity. Nat Commun. 2017;8:14059 pubmed publisher

Wang W, Xiao F, Wan P, Pan P, Zhang Y, Liu F, et al. EV71 3D Protein Binds with NLRP3 and Enhances the Assembly of Inflammasome Complex. PLoS Pathog. 2017;13:e1006123 pubmed publisher

Begay R, Tharp C, Martin A, Graw S, Sinagra G, Miani D, et al. FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy. JACC Basic Transl Sci. 2016;1:344-359 pubmed publisher

Xing J, Weng L, Yuan B, Wang Z, Jia L, Jin R, et al. Identification of a role for TRIM29 in the control of innate immunity in the respiratory tract. Nat Immunol. 2016;17:1373-1380 pubmed publisher

Pradère J, Hernandez C, Koppe C, Friedman R, Luedde T, Schwabe R. Negative regulation of NF-κB p65 activity by serine 536 phosphorylation. Sci Signal. 2016;9:ra85 pubmed publisher

Kubota Y, Nomura K, Katoh Y, Yamashita R, Kaneko K, Furuyama K. Novel Mechanisms for Heme-dependent Degradation of ALAS1 Protein as a Component of Negative Feedback Regulation of Heme Biosynthesis. J Biol Chem. 2016;291:20516-29 pubmed publisher

Whiting J, Ogier L, Forbush K, Bucko P, Gopalan J, Seternes O, et al. AKAP220 manages apical actin networks that coordinate aquaporin-2 location and renal water reabsorption. Proc Natl Acad Sci U S A. 2016;113:E4328-37 pubmed publisher

Ahmad I, Mui E, Galbraith L, Patel R, Tan E, Salji M, et al. Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer. Proc Natl Acad Sci U S A. 2016;113:8290-5 pubmed publisher

Yuan B, Cheng L, Gupta K, Chiang H, Gupta H, Sareddy G, et al. Tyrosine phosphorylation regulates ER? ubiquitination, protein turnover, and inhibition of breast cancer. Oncotarget. 2016;7:42585-42597 pubmed publisher

Sudhaharan T, Sem K, Liew H, Yu Y, Goh W, Chou A, et al. The Rho GTPase Rif signals through IRTKS, Eps8 and WAVE2 to generate dorsal membrane ruffles and filopodia. J Cell Sci. 2016;129:2829-40 pubmed publisher

Haley J, Tomar S, Pulliam N, Xiong S, Perkins S, Karpf A, et al. Functional characterization of a panel of high-grade serous ovarian cancer cell lines as representative experimental models of the disease. Oncotarget. 2016;7:32810-20 pubmed publisher

Hu L, Tan J, Yang X, Tan H, Xu X, You M, et al. Polysaccharide Extracted from Laminaria japonica Delays Intrinsic Skin Aging in Mice. Evid Based Complement Alternat Med. 2016;2016:5137386 pubmed publisher

Zhang Y, Liu J, Wang S, Luo X, Li Y, Lv Z, et al. The DEK oncogene activates VEGF expression and promotes tumor angiogenesis and growth in HIF-1α-dependent and -independent manners. Oncotarget. 2016;7:23740-56 pubmed publisher

Leblanc S, Wu Q, Lamba P, Sif S, Imbalzano A. Promoter-enhancer looping at the PPARγ2 locus during adipogenic differentiation requires the Prmt5 methyltransferase. Nucleic Acids Res. 2016;44:5133-47 pubmed publisher

Chen Z, Liu H, Lei S, Zhao B, Xia Z. LY294002 prevents lipopolysaccharide‑induced hepatitis in a murine model by suppressing IκB phosphorylation. Mol Med Rep. 2016;13:811-6 pubmed publisher

Wu G, Huang P, Ju X, Li Z, Wang Y. Lin28B over-expression mediates the repression of let-7 by hepatitis B virus X protein in hepatoma cells. Int J Clin Exp Med. 2015;8:15108-16 pubmed

Wronska A, Lawniczak A, Wierzbicki P, Kmiec Z. Age-Related Changes in Sirtuin 7 Expression in Calorie-Restricted and Refed Rats. Gerontology. 2016;62:304-10 pubmed publisher

Zetsche B, Gootenberg J, Abudayyeh O, Slaymaker I, Makarova K, Essletzbichler P, et al. Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system. Cell. 2015;163:759-71 pubmed publisher

Yan C, He Y, Xu Y, Shu G, Wang C, Yang Y, et al. Apolipoprotein A-IV Inhibits AgRP/NPY Neurons and Activates Pro-Opiomelanocortin Neurons in the Arcuate Nucleus. Neuroendocrinology. 2016;103:476-488 pubmed publisher

Stringer Reasor E, Baker G, Skor M, Kocherginsky M, Lengyel E, Fleming G, et al. Glucocorticoid receptor activation inhibits chemotherapy-induced cell death in high-grade serous ovarian carcinoma. Gynecol Oncol. 2015;138:656-62 pubmed publisher

Amantini C, Morelli M, Santoni M, Soriani A, Cardinali C, Farfariello V, et al. Sorafenib induces cathepsin B-mediated apoptosis of bladder cancer cells by regulating the Akt/PTEN pathway. The Akt inhibitor, perifosine, enhances the sorafenib-induced cytotoxicity against bladder cancer cells. Oncoscience. 2015;2:395-409 pubmed

Chen S, Smith B, Iype J, Prestipino A, Pfeifer D, Grundmann S, et al. MicroRNA-155-deficient dendritic cells cause less severe GVHD through reduced migration and defective inflammasome activation. Blood. 2015;126:103-12 pubmed publisher

Nakajima H, Kubo T, Ihara H, Hikida T, Danjo T, Nakatsuji M, et al. Nuclear-translocated Glyceraldehyde-3-phosphate Dehydrogenase Promotes Poly(ADP-ribose) Polymerase-1 Activation during Oxidative/Nitrosative Stress in Stroke. J Biol Chem. 2015;290:14493-503 pubmed publisher

Wu Q, Madany P, Akech J, Dobson J, Douthwright S, Browne G, et al. The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation. J Cell Physiol. 2015;230:2683-94 pubmed publisher

Boulay A, Mazeraud A, Cisternino S, Saubaméa B, Mailly P, Jourdren L, et al. Immune quiescence of the brain is set by astroglial connexin 43. J Neurosci. 2015;35:4427-39 pubmed publisher

Ramos D, Pellín Carcelén A, Agustí J, Murgui A, Jordá E, Pellín A, et al. Deregulation of glyceraldehyde-3-phosphate dehydrogenase expression during tumor progression of human cutaneous melanoma. Anticancer Res. 2015;35:439-44 pubmed

Hussain M, Battaglia A, Szczepanski S, Kaygusuz E, Toliat M, Sakakibara S, et al. Mutations in CKAP2L, the human homolog of the mouse Radmis gene, cause Filippi syndrome. Am J Hum Genet. 2014;95:622-32 pubmed publisher

Wiegering A, Korb D, Thalheimer A, Kämmerer U, Allmanritter J, Matthes N, et al. E7080 (lenvatinib), a multi-targeted tyrosine kinase inhibitor, demonstrates antitumor activities against colorectal cancer xenografts. Neoplasia. 2014;16:972-81 pubmed publisher

Pang M, Wu G, Hou X, Hou N, Liang L, Jia G, et al. LIN28B promotes colon cancer migration and recurrence. PLoS ONE. 2014;9:e109169 pubmed publisher

Weng L, Mitoma H, Trichot C, Tricot C, Bao M, Liu Y, et al. The E3 ubiquitin ligase tripartite motif 33 is essential for cytosolic RNA-induced NLRP3 inflammasome activation. J Immunol. 2014;193:3676-82 pubmed publisher

Shin M, Yao Q, Jun J, Bevans Fonti S, Yoo D, Han W, et al. Carotid body denervation prevents fasting hyperglycemia during chronic intermittent hypoxia. J Appl Physiol (1985). 2014;117:765-76 pubmed publisher

Yuan B, Cheng L, Chiang H, Xu X, Han Y, Su H, et al. A phosphotyrosine switch determines the antitumor activity of ER?. J Clin Invest. 2014;124:3378-90 pubmed publisher

Yamashita K, Alves A, Barbaro K, Santoro M. Bothrops jararaca venom metalloproteinases are essential for coagulopathy and increase plasma tissue factor levels during envenomation. PLoS Negl Trop Dis. 2014;8:e2814 pubmed publisher

Cen B, Xiong Y, Song J, Mahajan S, DuPont R, McEachern K, et al. The Pim-1 protein kinase is an important regulator of MET receptor tyrosine kinase levels and signaling. Mol Cell Biol. 2014;34:2517-32 pubmed publisher

Sun B, Kawahara M, Nagamune T. Modeling tandem AAG8-MEK inhibition in melanoma cells. Cancer Med. 2014;3:710-8 pubmed publisher

Miyamoto R, Otsuguro K, Yamaguchi S, Ito S. Contribution of cysteine aminotransferase and mercaptopyruvate sulfurtransferase to hydrogen sulfide production in peripheral neurons. J Neurochem. 2014;130:29-40 pubmed publisher

Bohonowych J, Hance M, Nolan K, DEFEE M, Parsons C, Isaacs J. Extracellular Hsp90 mediates an NF-?B dependent inflammatory stromal program: implications for the prostate tumor microenvironment. Prostate. 2014;74:395-407 pubmed publisher

Konradi S, Yasmin N, Haslwanter D, Weber M, Gesslbauer B, Sixt M, et al. Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial-mesenchymal transition ZEB1/2. Eur J Immunol. 2014;44:553-60 pubmed publisher

Mitoma H, Hanabuchi S, Kim T, Bao M, Zhang Z, Sugimoto N, et al. The DHX33 RNA helicase senses cytosolic RNA and activates the NLRP3 inflammasome. Immunity. 2013;39:123-35 pubmed publisher

Eaton S, Hough T, Fischer Colbrie R, Peters J. Maternal inheritance of the Gnas cluster mutation Ex1A-T affects size, implicating NESP55 in growth. Mamm Genome. 2013;24:276-85 pubmed publisher

Boonyaratanakornkit J, Schomacker H, Collins P, Schmidt A. Alix serves as an adaptor that allows human parainfluenza virus type 1 to interact with the host cell ESCRT system. PLoS ONE. 2013;8:e59462 pubmed publisher

Ziemann A, Hess S, Bhuwania R, Linder S, Kloppenburg P, Noegel A, et al. CRN2 enhances the invasiveness of glioblastoma cells. Neuro Oncol. 2013;15:548-61 pubmed publisher

Imbalzano K, Cohet N, Wu Q, Underwood J, Imbalzano A, Nickerson J. Nuclear shape changes are induced by knockdown of the SWI/SNF ATPase BRG1 and are independent of cytoskeletal connections. PLoS ONE. 2013;8:e55628 pubmed publisher

Wu Y, Zhang Y, Wang M, Li Q, Qu Z, Shi V, et al. Downregulation of HER3 by a novel antisense oligonucleotide, EZN-3920, improves the antitumor activity of EGFR and HER2 tyrosine kinase inhibitors in animal models. Mol Cancer Ther. 2013;12:427-37 pubmed publisher

Dutta D, Xu J, Kim J, Dunn W, Leeuwenburgh C. Upregulated autophagy protects cardiomyocytes from oxidative stress-induced toxicity. Autophagy. 2013;9:328-44 pubmed publisher

Zhang Z, Bao M, Lu N, Weng L, Yuan B, Liu Y. The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNA. Nat Immunol. 2013;14:172-8 pubmed publisher

Felver Gant J, Mack L, Dennis R, Eicher S, Cheng H. Genetic variations alter physiological responses following heat stress in 2 strains of laying hens. Poult Sci. 2012;91:1542-51 pubmed publisher

Leblanc S, Konda S, Wu Q, Hu Y, Oslowski C, SIF S, et al. Protein arginine methyltransferase 5 (Prmt5) promotes gene expression of peroxisome proliferator-activated receptor ?2 (PPAR?2) and its target genes during adipogenesis. Mol Endocrinol. 2012;26:583-97 pubmed publisher

Eaton S, Williamson C, Ball S, Beechey C, Moir L, Edwards J, et al. New mutations at the imprinted Gnas cluster show gene dosage effects of Gs? in postnatal growth and implicate XL?s in bone and fat metabolism but not in suckling. Mol Cell Biol. 2012;32:1017-29 pubmed publisher

Ahmad I, Patel R, Singh L, Nixon C, Seywright M, Barnetson R, et al. HER2 overcomes PTEN (loss)-induced senescence to cause aggressive prostate cancer. Proc Natl Acad Sci U S A. 2011;108:16392-7 pubmed publisher

Waks Z, Klein A, Silver P. Cell-to-cell variability of alternative RNA splicing. Mol Syst Biol. 2011;7:506 pubmed publisher

Haynes K, Silver P. Synthetic reversal of epigenetic silencing. J Biol Chem. 2011;286:27176-82 pubmed publisher

Goh W, Sudhaharan T, Lim K, Sem K, Lau C, Ahmed S. Rif-mDia1 interaction is involved in filopodium formation independent of Cdc42 and Rac effectors. J Biol Chem. 2011;286:13681-94 pubmed publisher

Schaap Nutt A, Higgins C, Amaro Carambot E, Nolan S, D Angelo C, Murphy B, et al. Identification of human parainfluenza virus type 2 (HPIV-2) V protein amino acid residues that reduce binding of V to MDA5 and attenuate HPIV-2 replication in nonhuman primates. J Virol. 2011;85:4007-19 pubmed publisher

Cheishvili D, Maayan C, Cohen Kupiec R, Lefler S, Weil M, Ast G, et al. IKAP/Elp1 involvement in cytoskeleton regulation and implication for familial dysautonomia. Hum Mol Genet. 2011;20:1585-94 pubmed publisher

Beharry Z, Mahajan S, Zemskova M, Lin Y, Tholanikunnel B, Xia Z, et al. The Pim protein kinases regulate energy metabolism and cell growth. Proc Natl Acad Sci U S A. 2011;108:528-33 pubmed publisher

Zhang Y, Qu Z, Kim S, Shi V, Liao B, Kraft P, et al. Down-modulation of cancer targets using locked nucleic acid (LNA)-based antisense oligonucleotides without transfection. Gene Ther. 2011;18:326-33 pubmed publisher

Wilber A, Hargrove P, Kim Y, Riberdy J, Sankaran V, Papanikolaou E, et al. Therapeutic levels of fetal hemoglobin in erythroid progeny of ?-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer. Blood. 2011;117:2817-26 pubmed publisher

Boonyaratanakornkit J, Bartlett E, Schomacker H, Surman S, Akira S, Bae Y, et al. The C proteins of human parainfluenza virus type 1 limit double-stranded RNA accumulation that would otherwise trigger activation of MDA5 and protein kinase R. J Virol. 2011;85:1495-506 pubmed publisher

Marecki J, Ronis M, Shankar K, Badger T. Hyperinsulinemia and ectopic fat deposition can develop in the face of hyperadiponectinemia in young obese rats. J Nutr Biochem. 2011;22:142-52 pubmed publisher

Schaap Nutt A, D Angelo C, Scull M, Amaro Carambot E, Nishio M, Pickles R, et al. Human parainfluenza virus type 2 V protein inhibits interferon production and signaling and is required for replication in non-human primates. Virology. 2010;397:285-98 pubmed publisher

Halon M, Sielicka Dudzin A, Wozniak M, Ziolkowski W, Nyka W, Herbik M, et al. Up-regulation of ferritin ubiquitination in skeletal muscle of transgenic rats bearing the G93A hmSOD1 gene mutation. Neuromuscul Disord. 2010;20:29-33 pubmed publisher

Abuhatzira L, Shemer R, Razin A. MeCP2 involvement in the regulation of neuronal alpha-tubulin production. Hum Mol Genet. 2009;18:1415-23 pubmed publisher

Finkin S, Aylon Y, Anzi S, Oren M, Shaulian E. Fbw7 regulates the activity of endoreduplication mediators and the p53 pathway to prevent drug-induced polyploidy. Oncogene. 2008;27:4411-21 pubmed publisher

Bae B, Hara M, Cascio M, Wellington C, Hayden M, Ross C, et al. Mutant huntingtin: nuclear translocation and cytotoxicity mediated by GAPDH. Proc Natl Acad Sci U S A. 2006;103:3405-9 pubmed

Sampath P, Mazumder B, Seshadri V, Gerber C, Chavatte L, Kinter M, et al. Noncanonical function of glutamyl-prolyl-tRNA synthetase: gene-specific silencing of translation. Cell. 2004;119:195-208 pubmed

Zheng L, Roeder R, Luo Y. S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component. Cell. 2003;114:255-66 pubmed

Yuhki N, Beck T, Stephens R, Nishigaki Y, Newmann K, O Brien S. Comparative genome organization of human, murine, and feline MHC class II region. Genome Res. 2003;13:1169-79 pubmed

Tisdale E. Glyceraldehyde-3-phosphate dehydrogenase is phosphorylated by protein kinase Ciota /lambda and plays a role in microtubule dynamics in the early secretory pathway. J Biol Chem. 2002;277:3334-41 pubmed