This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Monosialoganglioside G M2 from bovine brain
catalog :
G8397
citations: 34
Reference
Shahine A, Reinink P, Reijneveld J, Gras S, Holzheimer M, Cheng T, et al. A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids. Nat Commun. 2019;10:56 pubmed publisher
Abalem M, Francischini S, Carricondo P, Graziano R. Fundus autofluorescence in Tay-Sachs disease. JAMA Ophthalmol. 2014;132:876 pubmed publisher
Krishnamoorthy K, Eichler F, Rapalino O, Frosch M. Case records of the Massachusetts General Hospital. Case 14-2014. An 11-month-old girl with developmental delay. N Engl J Med. 2014;370:1830-41 pubmed publisher
Kang S, Heo T, Kim S. Altered levels of α-synuclein and sphingolipids in Batten disease lymphoblast cells. Gene. 2014;539:181-5 pubmed publisher
Eggermont A, Suciu S, Rutkowski P, Marsden J, Santinami M, Corrie P, et al. Adjuvant ganglioside GM2-KLH/QS-21 vaccination versus observation after resection of primary tumor > 1.5 mm in patients with stage II melanoma: results of the EORTC 18961 randomized phase III trial. J Clin Oncol. 2013;31:3831-7 pubmed publisher
Rupp A, Galban Horcajo F, Bianchi E, Dondi M, Penderis J, Cappell J, et al. Anti-GM2 ganglioside antibodies are a biomarker for acute canine polyradiculoneuritis. J Peripher Nerv Syst. 2013;18:75-88 pubmed publisher
Mardinoglu A, Agren R, Kampf C, Asplund A, Nookaew I, Jacobson P, et al. Integration of clinical data with a genome-scale metabolic model of the human adipocyte. Mol Syst Biol. 2013;9:649 pubmed publisher
Sinici I, Yonekawa S, Tkachyova I, Gray S, Samulski R, Wakarchuk W, et al. In cellulo examination of a beta-alpha hybrid construct of beta-hexosaminidase A subunits, reported to interact with the GM2 activator protein and hydrolyze GM2 ganglioside. PLoS ONE. 2013;8:e57908 pubmed publisher
Yamaguchi T, Uno T, Uekusa Y, Yagi Utsumi M, Kato K. Ganglioside-embedding small bicelles for probing membrane-landing processes of intrinsically disordered proteins. Chem Commun (Camb). 2013;49:1235-7 pubmed publisher
Sargeant T, Drage D, Wang S, Apostolakis A, Cox T, Cachón González M. Characterization of inducible models of Tay-Sachs and related disease. PLoS Genet. 2012;8:e1002943 pubmed publisher
Liu F, Liu T, Qu M, Yang Q. Molecular and biochemical characterization of a novel ?-N-acetyl-D-hexosaminidase with broad substrate-spectrum from the Aisan corn borer, Ostrinia furnacalis. Int J Biol Sci. 2012;8:1085-96 pubmed
Kim C, Seo J, Cha H. Functional interaction analysis of GM1-related carbohydrates and Vibrio cholerae toxins using carbohydrate microarray. Anal Chem. 2012;84:6884-90 pubmed publisher
HOSHINO T, Uchiyama Y, Ito E, Osawa S, Ohashi T. Simultaneous development of acute disseminated encephalomyelitis and Guillain-Barré syndrome associated with H1N1 09 influenza vaccination. Intern Med. 2012;51:1595-8 pubmed
Pernber Z, Blennow K, Bogdanovic N, Mansson J, Blomqvist M. Altered distribution of the gangliosides GM1 and GM2 in Alzheimer's disease. Dement Geriatr Cogn Disord. 2012;33:174-88 pubmed publisher
Wilkinson F, Holley R, Langford Smith K, Badrinath S, Liao A, Langford Smith A, et al. Neuropathology in mouse models of mucopolysaccharidosis type I, IIIA and IIIB. PLoS ONE. 2012;7:e35787 pubmed publisher
Keilani S, Lun Y, Stevens A, Williams H, Sjoberg E, Khanna R, et al. Lysosomal dysfunction in a mouse model of Sandhoff disease leads to accumulation of ganglioside-bound amyloid-? peptide. J Neurosci. 2012;32:5223-36 pubmed publisher
Dawson G, Fuller M, Helmsley K, Hopwood J. Abnormal gangliosides are localized in lipid rafts in Sanfilippo (MPS3a) mouse brain. Neurochem Res. 2012;37:1372-80 pubmed publisher
Saito M, Chakraborty G, Shah R, Mao R, Kumar A, Yang D, et al. Elevation of GM2 ganglioside during ethanol-induced apoptotic neurodegeneration in the developing mouse brain. J Neurochem. 2012;121:649-61 pubmed publisher
Arthur J, Lee J, Snyder E, Seyfried T. Therapeutic effects of stem cells and substrate reduction in juvenile Sandhoff mice. Neurochem Res. 2012;37:1335-43 pubmed publisher
Kodama T, Togawa T, Tsukimura T, Kawashima I, Matsuoka K, Kitakaze K, et al. Lyso-GM2 ganglioside: a possible biomarker of Tay-Sachs disease and Sandhoff disease. PLoS ONE. 2011;6:e29074 pubmed publisher
Nagahori N, Uchida M, Kinjo M, Yamashita T. Use of carbohydrate-conjugated nanoparticles for an integrated approach to functional imaging of glycans and understanding of their molecular mechanisms. Curr Pharm Biotechnol. 2012;13:2612-6 pubmed
Passos O, Fernandes P, Ramos M. QM/MM study of the catalytic mechanism of GalNAc removal from GM2 ganglioside catalyzed by human β-hexosaminidaseA. J Phys Chem B. 2011;115:14751-9 pubmed publisher
Klisch K, Contreras D, Sun X, Brehm R, Bergmann M, Alberio R. The Sda/GM2-glycan is a carbohydrate marker of porcine primordial germ cells and of a subpopulation of spermatogonia in cattle, pigs, horses and llama. Reproduction. 2011;142:667-74 pubmed publisher
Yamada T, Bando H, Takeuchi S, Kita K, Li Q, Wang W, et al. Genetically engineered humanized anti-ganglioside GM2 antibody against multiple organ metastasis produced by GM2-expressing small-cell lung cancer cells. Cancer Sci. 2011;102:2157-63 pubmed publisher
Whitehead B, O Brien M, Jack B, Mitchell D. Experiences of dying, death and bereavement in motor neurone disease: a qualitative study. Palliat Med. 2012;26:368-78 pubmed publisher
Matsuoka K, Tsuji D, Taki T, Itoh K. Thymic involution and corticosterone level in Sandhoff disease model mice: new aspects the pathogenesis of GM2 gangliosidosis. J Inherit Metab Dis. 2011;34:1061-8 pubmed publisher
Smyth K, Fritzler M, Kirton A. Acquired infantile abducens palsy associated with anti-GM2 antibodies. Pediatr Neurol. 2011;44:459-62 pubmed publisher
Tetala K, Heikema A, Pukin A, Weijers C, Tio Gillen A, Gilbert M, et al. Selective depletion of neuropathy-related antibodies from human serum by monolithic affinity columns containing ganglioside mimics. J Med Chem. 2011;54:3500-5 pubmed publisher
Matsuoka K, Tamura T, Tsuji D, Dohzono Y, Kitakaze K, Ohno K, et al. Therapeutic potential of intracerebroventricular replacement of modified human ?-hexosaminidase B for GM2 gangliosidosis. Mol Ther. 2011;19:1017-24 pubmed publisher
Hovakimyan M, Stachs O, Reichard M, Mascher H, Lukas J, Frech M, et al. Morphological alterations of the cornea in the mouse model of niemann-pick disease type c1. Cornea. 2011;30:796-803 pubmed publisher
Fernández Marrero Y, Hernández T, Roque Navarro L, Talavera A, Moreno E, Griñán T, et al. Switching on cytotoxicity by a single mutation at the heavy chain variable region of an anti-ganglioside antibody. Mol Immunol. 2011;48:1059-67 pubmed publisher
Sorice M, Garofalo T, Misasi R, Dolo V, Lucania G, Sansolini T, et al. Glycosphingolipid domains on cell plasma membrane. Biosci Rep. 1999;19:197-208 pubmed
Nohara K, Wang F, Spiegel S. Glycosphingolipid composition of MDA-MB-231 and MCF-7 human breast cancer cell lines. Breast Cancer Res Treat. 1998;48:149-57 pubmed
Yohe H, Ye S, Reinhold B, Reinhold V. Structural characterization of the disialogangliosides of murine peritoneal macrophages. Glycobiology. 1997;7:1215-27 pubmed
product information
Catalog Number :
G8397
Product Name :
Monosialoganglioside G M2 from bovine brain
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥95% (TLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA