This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Disialoganglioside GD 1b from bovine brain
catalog :
G8146
citations: 29
Reference
Xu X, Denic A, Jordan L, Wittenberg N, Warrington A, Wootla B, et al. A natural human IgM that binds to gangliosides is therapeutic in murine models of amyotrophic lateral sclerosis. Dis Model Mech. 2015;8:831-42 pubmed publisher
Sekino Suzuki N, Yuyama K, Miki T, Kaneda M, Suzuki H, Yamamoto N, et al. Involvement of gangliosides in the process of Cbp/PAG phosphorylation by Lyn in developing cerebellar growth cones. J Neurochem. 2013;124:514-22 pubmed publisher
Venkateshwari S, Veluraja K. Molecular Modelling and Molecular Dynamics studies of GD1A, GD1B and their complexes with BoNT/B--perspectives in interaction and specificity. J Struct Biol. 2012;180:497-508 pubmed publisher
Moyano A, Comín R, Vilcaes A, Funes S, Roth G, Irazoqui F, et al. Novel antibodies reacting with two neighboring gangliosides are induced in rabbits immunized with bovine brain gangliosides. Glycobiology. 2012;22:1768-74 pubmed publisher
Uncini A. A common mechanism and a new categorization for anti-ganglioside antibody-mediated neuropathies. Exp Neurol. 2012;235:513-6 pubmed publisher
Viljetić B, Labak I, Majić S, Stambuk A, Heffer M. Distribution of mono-, di- and trisialo gangliosides in the brain of Actinopterygian fishes. Biochim Biophys Acta. 2012;1820:1437-43 pubmed publisher
Susuki K, Yuki N, Schafer D, Hirata K, Zhang G, Funakoshi K, et al. Dysfunction of nodes of Ranvier: a mechanism for anti-ganglioside antibody-mediated neuropathies. Exp Neurol. 2012;233:534-42 pubmed publisher
Tellier S, Gerdelat Mas A, Karsenty C, Cances C, Tison C, Chaix Y, et al. [Guillain-Barré syndrome in a child with normal tendon reflexes]. Arch Pediatr. 2012;19:51-4 pubmed publisher
Lai L, Bumstead J, Liu Y, Garnett J, Campanero Rhodes M, Blake D, et al. The role of sialyl glycan recognition in host tissue tropism of the avian parasite Eimeria tenella. PLoS Pathog. 2011;7:e1002296 pubmed publisher
Jeong S, Nam J, Kwon M, Kim J, Kim J. Nystagmus and ataxia associated with antiganglioside antibodies. J Neuroophthalmol. 2011;31:326-30 pubmed publisher
Fujimoto T, Fukuda Y, Eguchi K, Kusunoki S. [Case report; A case of anti-GD1b antibody positive pure motor form Guillain-Barré syndrome with good response to combined IVIg and steroid therapy]. Nihon Naika Gakkai Zasshi. 2011;100:1651-3 pubmed
Mazucato V, Silveira E Souza A, Nicoletti L, Jamur M, Oliver C. GD1b-derived gangliosides modulate Fc?RI endocytosis in mast cells. J Histochem Cytochem. 2011;59:428-40 pubmed publisher
Valle Argos B, Gomez Nicola D, Nieto Sampedro M. Glioma growth inhibition by neurostatin and O-But GD1b. Neuro Oncol. 2010;12:1135-46 pubmed publisher
Dong Y, Ikeda K, Hamamura K, Zhang Q, Kondo Y, Matsumoto Y, et al. GM1?/?GD1b?/?GA1 synthase expression results in the reduced cancer phenotypes with modulation of composition and raft-localization of gangliosides in a melanoma cell line. Cancer Sci. 2010;101:2039-47 pubmed publisher
Dewil M, Robberecht W, Van Damme P. An unusual presentation of Guillain-Barré syndrome associated with monospecific anti-GD1b antibodies. J Neurol Neurosurg Psychiatry. 2010;81:587-8 pubmed publisher
Lardone R, Yuki N, Odaka M, Daniotti J, Irazoqui F, Nores G. Anti-GM1 IgG antibodies in Guillain-Barré syndrome: fine specificity is associated with disease severity. J Neurol Neurosurg Psychiatry. 2010;81:629-33 pubmed publisher
Attarian S, Boucraut J, Hubert A, Uzenot D, Delmont E, Verschueren A, et al. Chronic ataxic neuropathies associated with anti-GD1b IgM antibodies: response to IVIg therapy. J Neurol Neurosurg Psychiatry. 2010;81:61-4 pubmed publisher
Serb A, Schiopu C, Flangea C, Vukelic Z, Sisu E, Zagrean L, et al. High-throughput analysis of gangliosides in defined regions of fetal brain by fully automated chip-based nanoelectrospray ionization multi-stage mass spectrometry. Eur J Mass Spectrom (Chichester). 2009;15:541-53 pubmed publisher
Liu J, Willison H, Pedrosa Domellöf F. Immunolocalization of GQ1b and related gangliosides in human extraocular neuromuscular junctions and muscle spindles. Invest Ophthalmol Vis Sci. 2009;50:3226-32 pubmed publisher
Simpson B, Rajabally Y. Sensori-motor Guillain-Barré syndrome with anti-GD1b antibodies following influenza A infection. Eur J Neurol. 2009;16:e81 pubmed publisher
Yardimci N, Gulsen S, Avci A, Altinors N, Zileli T, Can U. Can subdural hematoma be a trigger for Guillain-Barré syndrome?. Int J Neurosci. 2009;119:366-72 pubmed publisher
Kaida K, Kamakura K, Ogawa G, Ueda M, Motoyoshi K, Arita M, et al. GD1b-specific antibody induces ataxia in Guillain-Barre syndrome. Neurology. 2008;71:196-201 pubmed publisher
Yoshino H, Ariga T, Suzuki A, Yu R, Miyatake T. Identification of gangliosides recognized by IgG anti-GalNAc-GD1a antibodies in bovine spinal motor neurons and motor nerves. Brain Res. 2008;1227:216-20 pubmed publisher
Silveira E Souza A, Mazucato V, de Castro R, Matioli F, Ciancaglini P, de Paiva Paulino T, et al. The alpha-galactosyl derivatives of ganglioside GD(1b) are essential for the organization of lipid rafts in RBL-2H3 mast cells. Exp Cell Res. 2008;314:2515-28 pubmed publisher
Takada K, Shimizu J, Kusunoki S. Apoptosis of primary sensory neurons in GD1b-induced sensory ataxic neuropathy. Exp Neurol. 2008;209:279-83 pubmed
Nobile Orazio E, Gallia F, Terenghi F, Allaria S, Giannotta C, Carpo M. How useful are anti-neural IgM antibodies in the diagnosis of chronic immune-mediated neuropathies?. J Neurol Sci. 2008;266:156-63 pubmed
Couesnon A, Pereira Y, Popoff M. Receptor-mediated transcytosis of botulinum neurotoxin A through intestinal cell monolayers. Cell Microbiol. 2008;10:375-87 pubmed
Daniotti J, Martina J, Zurita A, Maccioni H. Mouse beta 1,3-galactosyltransferase (GA1/GM1/GD1b synthase): protein characterization, tissue expression, and developmental regulation in neural retina. J Neurosci Res. 1999;58:318-27 pubmed
Favaron M, Manev H, Alho H, Bertolino M, Ferret B, Guidotti A, et al. Gangliosides prevent glutamate and kainate neurotoxicity in primary neuronal cultures of neonatal rat cerebellum and cortex. Proc Natl Acad Sci U S A. 1988;85:7351-5 pubmed
product information
Catalog Number :
G8146
Product Name :
Disialoganglioside GD 1b from bovine brain
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
~95%, lyophilized powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA