Chaves Pérez A, Yilmaz M, Perna C, de la Rosa S, Djouder N. URI is required to maintain intestinal architecture during ionizing radiation. Science. 2019;364: pubmed publisher

Luo Y, Barrios Rodiles M, Gupta G, Zhang Y, Ogunjimi A, Bashkurov M, et al. Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility. Nat Commun. 2019;10:2356 pubmed publisher

Jennings E, Esposito D, Rittinger K, Thurston T. Structure-function analyses of the bacterial zinc metalloprotease effector protein GtgA uncover key residues required for deactivating NF-κB. J Biol Chem. 2018;293:15316-15329 pubmed publisher

Kayama K, Watanabe S, Takafuji T, Tsuji T, Hironaka K, Matsumoto M, et al. GRWD1 negatively regulates p53 via the RPL11-MDM2 pathway and promotes tumorigenesis. EMBO Rep. 2017;18:123-137 pubmed publisher

Thomas G, Bandopadhyay K, Sutradhar S, Renjith M, Singh P, Gireesh K, et al. EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice. Nat Commun. 2016;7:11665 pubmed publisher

Ma K, Zhen X, Zhou B, Gan N, Cao Y, Fan C, et al. The bacterial deubiquitinase Ceg23 regulates the association of Lys-63-linked polyubiquitin molecules on the Legionella phagosome. J Biol Chem. 2020;295:1646-1657 pubmed publisher

Zhang M, Liang C, Chen Q, Yan H, Xu J, Zhao H, et al. Histone H2A phosphorylation recruits topoisomerase IIα to centromeres to safeguard genomic stability. EMBO J. 2020;39:e101863 pubmed publisher

Saila S, Gyanwali G, Hussain M, Gianfelice A, Ireton K. The Host GTPase Arf1 and Its Effectors AP1 and PICK1 Stimulate Actin Polymerization and Exocytosis To Promote Entry of Listeria monocytogenes. Infect Immun. 2020;88: pubmed publisher

Yokoyama T, Yukuhiro M, Iwasaki Y, Tanaka C, Sankoda K, Fujiwara R, et al. Identification of candidate molecular targets of the novel antineoplastic antimitotic NP-10. Sci Rep. 2019;9:16825 pubmed publisher

Yang Y, Willis T, Button R, Strang C, Fu Y, Wen X, et al. Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response. Nat Commun. 2019;10:3759 pubmed publisher

Nunes de Almeida F, Walther R, Pressé M, Vlassaks E, Pichaud F. Cdc42 defines apical identity and regulates epithelial morphogenesis by promoting apical recruitment of Par6-aPKC and Crumbs. Development. 2019;146: pubmed publisher

Jankowski S, Pohlmann T, Baumann S, Müntjes K, Devan S, Zander S, et al. The multi PAM2 protein Upa2 functions as novel core component of endosomal mRNA transport. EMBO Rep. 2019;20:e47381 pubmed publisher

Rushing A, Rushing B, Hoang K, Sanders S, Peloponese J, Polakowski N, et al. HTLV-1 basic leucine zipper factor protects cells from oxidative stress by upregulating expression of Heme Oxygenase I. PLoS Pathog. 2019;15:e1007922 pubmed publisher

Diring J, Mouilleron S, McDonald N, Treisman R. RPEL-family rhoGAPs link Rac/Cdc42 GTP loading to G-actin availability. Nat Cell Biol. 2019;: pubmed publisher

Amorim Silva V, Garcia Moreno A, Castillo A, Lakhssassi N, Esteban del Valle A, Pérez Sancho J, et al. TTL proteins scaffold brassinosteroid signaling components at the plasma membrane to optimize signal transduction in Arabidopsis. Plant Cell. 2019;: pubmed publisher

Mao Y, Tu R, Huang Y, Mao D, Yang Z, Lau P, et al. The exocyst functions in niche cells to promote germline stem cell differentiation by directly controlling EGFR membrane trafficking. Development. 2019;: pubmed publisher

Shokri L, Inukai S, Hafner A, Weinand K, Hens K, Vedenko A, et al. A Comprehensive Drosophila melanogaster Transcription Factor Interactome. Cell Rep. 2019;27:955-970.e7 pubmed publisher

Jiang J, Chai X, Manavski N, Williams Carrier R, He B, Brachmann A, et al. An RNA Chaperone-Like Protein Plays Critical Roles in Chloroplast mRNA Stability and Translation in Arabidopsis and Maize. Plant Cell. 2019;31:1308-1327 pubmed publisher

Rogers J, Waters C, Seegar T, Jarrett S, Hallworth A, Blacklow S, et al. Bispecific Forkhead Transcription Factor FoxN3 Recognizes Two Distinct Motifs with Different DNA Shapes. Mol Cell. 2019;74:245-253.e6 pubmed publisher

Shao J, Lu J, Zhu W, Yu H, Jing X, Wang Y, et al. Derepression of LOXL4 inhibits liver cancer growth by reactivating compromised p53. Cell Death Differ. 2019;: pubmed publisher

Huang L, Li L, Tien C, Labarbera D, Chen C. Targeting HIV-1 Protease Autoprocessing for High-throughput Drug Discovery and Drug Resistance Assessment. Sci Rep. 2019;9:301 pubmed publisher

Gemperle J, Dibus M, Koudelková L, Rosel D, Brabek J. The interaction of p130Cas with PKN3 promotes malignant growth. Mol Oncol. 2019;13:264-289 pubmed publisher

He W, Mazzuca P, Yuan W, Varney K, Bugatti A, Cagnotto A, et al. Identification of amino acid residues critical for the B cell growth-promoting activity of HIV-1 matrix protein p17 variants. Biochim Biophys Acta Gen Subj. 2019;1863:13-24 pubmed publisher

An T, Liu Y, Gourguechon S, Wang C, Li Z. CDK Phosphorylation of Translation Initiation Factors Couples Protein Translation with Cell-Cycle Transition. Cell Rep. 2018;25:3204-3214.e5 pubmed publisher

Czeredys M, Vigont V, Boeva V, Mikoshiba K, Kaznacheyeva E, Kuznicki J. Huntingtin-Associated Protein 1A Regulates Store-Operated Calcium Entry in Medium Spiny Neurons From Transgenic YAC128 Mice, a Model of Huntington's Disease. Front Cell Neurosci. 2018;12:381 pubmed publisher

Kandachar V, Tam B, Moritz O, Deretic D. An interaction network between the SNARE VAMP7 and Rab GTPases within a ciliary membrane-targeting complex. J Cell Sci. 2018;131: pubmed publisher

Lee B, Weber Z, Zourelidou M, Hofmeister B, Schmitz R, Schwechheimer C, et al. Arabidopsis Protein Kinase D6PKL3 Is Involved in the Formation of Distinct Plasma Membrane Aperture Domains on the Pollen Surface. Plant Cell. 2018;30:2038-2056 pubmed publisher

Aweida D, Rudesky I, Volodin A, Shimko E, Cohen S. GSK3-β promotes calpain-1-mediated desmin filament depolymerization and myofibril loss in atrophy. J Cell Biol. 2018;217:3698-3714 pubmed publisher

Watanabe S, Fujiyama H, Takafuji T, Kayama K, Matsumoto M, Nakayama K, et al. GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system. J Cell Sci. 2018;131: pubmed publisher

Nielsen J, Nordgaard C, Tollenaere M, Bekker Jensen S. Osmotic Stress Blocks Mobility and Dynamic Regulation of Centriolar Satellites. Cells. 2018;7: pubmed publisher

Kullmann L, Krahn M. Redundant regulation of localization and protein stability of DmPar3. Cell Mol Life Sci. 2018;75:3269-3282 pubmed publisher

Draime A, Bridoux L, Belpaire M, Pringels T, Tys J, Rezsohazy R. PRDM14, a putative histone methyl-transferase, interacts with and decreases the stability and activity of the HOXA1 transcription factor. Biochim Biophys Acta Gene Regul Mech. 2018;1861:534-542 pubmed publisher

Draime A, Bridoux L, Belpaire M, Pringels T, Degand H, Morsomme P, et al. The O-GlcNAc transferase OGT interacts with and post-translationally modifies the transcription factor HOXA1. FEBS Lett. 2018;592:1185-1201 pubmed publisher

Kruppa A, Kishi Itakura C, Masters T, Rorbach J, Grice G, Kendrick Jones J, et al. Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria. Dev Cell. 2018;44:484-499.e6 pubmed publisher

Tien C, Huang L, Watanabe S, Speidel J, Carter C, Chen C. Context-dependent autoprocessing of human immunodeficiency virus type 1 protease precursors. PLoS ONE. 2018;13:e0191372 pubmed publisher

Hohenstatt M, Mikulski P, Komarynets O, Klose C, Kycia I, Jeltsch A, et al. PWWP-DOMAIN INTERACTOR OF POLYCOMBS1 Interacts with Polycomb-Group Proteins and Histones and Regulates Arabidopsis Flowering and Development. Plant Cell. 2018;30:117-133 pubmed publisher

Xia P, Wang S, Xiong Z, Zhu X, Ye B, Du Y, et al. The ER membrane adaptor ERAdP senses the bacterial second messenger c-di-AMP and initiates anti-bacterial immunity. Nat Immunol. 2018;19:141-150 pubmed publisher

Bagchi R, Melnyk C, Christ G, Winkler M, Kirchsteiner K, Salehin M, et al. The Arabidopsis ALF4 protein is a regulator of SCF E3 ligases. EMBO J. 2018;37:255-268 pubmed publisher

Liang C, Chen Q, Yi Q, Zhang M, Yan H, Zhang B, et al. A kinase-dependent role for Haspin in antagonizing Wapl and protecting mitotic centromere cohesion. EMBO Rep. 2018;19:43-56 pubmed publisher

Oldrini B, Hsieh W, Erdjument Bromage H, Codega P, Carro M, Curiel García A, et al. EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer. Nat Commun. 2017;8:2035 pubmed publisher

Yang S, Yang H, Chang R, Yin P, Yang Y, Yang W, et al. MANF regulates hypothalamic control of food intake and body weight. Nat Commun. 2017;8:579 pubmed publisher

Qi W, Manfield I, Muench S, Baker A. AtSPX1 affects the AtPHR1-DNA-binding equilibrium by binding monomeric AtPHR1 in solution. Biochem J. 2017;474:3675-3687 pubmed publisher

Lombardi L, Zaghlula M, Sztainberg Y, BAKER S, Klisch T, Tang A, et al. An RNA interference screen identifies druggable regulators of MeCP2 stability. Sci Transl Med. 2017;9: pubmed publisher

Gemperle J, Hexnerová R, Lepsik M, Tesina P, Dibus M, Novotny M, et al. Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners. Sci Rep. 2017;7:8057 pubmed publisher

Dogliotti G, Kullmann L, Dhumale P, Thiele C, Panichkina O, Mendl G, et al. Membrane-binding and activation of LKB1 by phosphatidic acid is essential for development and tumour suppression. Nat Commun. 2017;8:15747 pubmed publisher

Kanie T, Abbott K, Mooney N, Plowey E, Demeter J, JACKSON P. The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base. Dev Cell. 2017;42:22-36.e12 pubmed publisher

Winkler M, Niemeyer M, Hellmuth A, Janitza P, Christ G, Samodelov S, et al. Variation in auxin sensing guides AUX/IAA transcriptional repressor ubiquitylation and destruction. Nat Commun. 2017;8:15706 pubmed publisher

Veß A, Blache U, Leitner L, Kurz A, Ehrenpfordt A, Sixt M, et al. A dual phenotype of MDA-MB-468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity. J Cell Sci. 2017;130:2172-2184 pubmed publisher

Qiu J, Yu K, Fei X, Liu Y, Nakayasu E, Piehowski P, et al. A unique deubiquitinase that deconjugates phosphoribosyl-linked protein ubiquitination. Cell Res. 2017;27:865-881 pubmed publisher

Durkin C, Leite F, Cordeiro J, Handa Y, Arakawa Y, Valderrama F, et al. RhoD Inhibits RhoC-ROCK-Dependent Cell Contraction via PAK6. Dev Cell. 2017;41:315-329.e7 pubmed publisher

Law F, Seo J, Wang Z, Deleon J, Bolis Y, Brown A, et al. The VPS34 PI3K negatively regulates RAB-5 during endosome maturation. J Cell Sci. 2017;130:2007-2017 pubmed publisher

Ren D, Fisher L, Zhao J, Wang L, Williams B, Goldberg M, et al. Cell cycle-dependent regulation of Greatwall kinase by protein phosphatase 1 and regulatory subunit 3B. J Biol Chem. 2017;292:10026-10034 pubmed publisher

Ding Y, Wang B, Chen X, Zhou Y, Ge J. Staurosporine suppresses survival of HepG2 cancer cells through Omi/HtrA2-mediated inhibition of PI3K/Akt signaling pathway. Tumour Biol. 2017;39:1010428317694317 pubmed publisher

Castaño Miquel L, Mas A, Teixeira I, Seguí J, Perearnau A, Thampi B, et al. SUMOylation Inhibition Mediated by Disruption of SUMO E1-E2 Interactions Confers Plant Susceptibility to Necrotrophic Fungal Pathogens. Mol Plant. 2017;10:709-720 pubmed publisher

Francis J, Newman L, Cunningham L, Kahn R. A Trimer Consisting of the Tubulin-specific Chaperone D (TBCD), Regulatory GTPase ARL2, and β-Tubulin Is Required for Maintaining the Microtubule Network. J Biol Chem. 2017;292:4336-4349 pubmed publisher

Zhou H, Liu Y, Zhu R, Ding F, Wan Y, Li Y, et al. FBXO32 suppresses breast cancer tumorigenesis through targeting KLF4 to proteasomal degradation. Oncogene. 2017;36:3312-3321 pubmed publisher

Sun W, Lee S, Huang X, Liu S, Inayathullah M, Kim K, et al. Attenuation of synaptic toxicity and MARK4/PAR1-mediated Tau phosphorylation by methylene blue for Alzheimer's disease treatment. Sci Rep. 2016;6:34784 pubmed publisher

Zhang Y, Luo Y, Lyu R, Chen J, Liu R, Li D, et al. Proto-Oncogenic Src Phosphorylates EB1 to Regulate the Microtubule-Focal Adhesion Crosstalk and Stimulate Cell Migration. Theranostics. 2016;6:2129-2140 pubmed

Harrison J, Cornett E, Goldfarb D, DaRosa P, Li Z, Yan F, et al. Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1. elife. 2016;5: pubmed publisher

Gunn A, Banos Pinero B, Paschke P, Sanchez Pulido L, Ariza A, Day J, et al. The role of ADP-ribosylation in regulating DNA interstrand crosslink repair. J Cell Sci. 2016;129:3845-3858 pubmed

Taminiau A, Draime A, Tys J, Lambert B, Vandeputte J, Nguyen N, et al. HOXA1 binds RBCK1/HOIL-1 and TRAF2 and modulates the TNF/NF-?B pathway in a transcription-independent manner. Nucleic Acids Res. 2016;44:7331-49 pubmed publisher

Ambrosi C, Ren C, Spagnol G, Cavin G, CONE A, Grintsevich E, et al. Connexin43 Forms Supramolecular Complexes through Non-Overlapping Binding Sites for Drebrin, Tubulin, and ZO-1. PLoS ONE. 2016;11:e0157073 pubmed publisher

Lyon A, Morin G, Moritz M, Yabut K, Vojnar T, Zelter A, et al. Higher-order oligomerization of Spc110p drives ?-tubulin ring complex assembly. Mol Biol Cell. 2016;27:2245-58 pubmed publisher

Andrews F, Shinsky S, Shanle E, Bridgers J, Gest A, Tsun I, et al. The Taf14 YEATS domain is a reader of histone crotonylation. Nat Chem Biol. 2016;12:396-8 pubmed publisher

Dowd G, Bhalla M, Kean B, Thomas R, Ireton K. Role of Host Type IA Phosphoinositide 3-Kinase Pathway Components in Invasin-Mediated Internalization of Yersinia enterocolitica. Infect Immun. 2016;84:1826-1841 pubmed publisher

Paci A, Liu P, Zhang L, Zhao R. The Proteasome Subunit Rpn8 Interacts with the Small Nucleolar RNA Protein (snoRNP) Assembly Protein Pih1 and Mediates Its Ubiquitin-independent Degradation in Saccharomyces cerevisiae. J Biol Chem. 2016;291:11761-75 pubmed publisher

Qiu J, Sheedlo M, Yu K, Tan Y, Nakayasu E, Das C, et al. Ubiquitination independent of E1 and E2 enzymes by bacterial effectors. Nature. 2016;533:120-4 pubmed publisher

Randise Hinchliff C, Coukos R, Sood V, Sumner M, Zdraljevic S, Meldi Sholl L, et al. Strategies to regulate transcription factor-mediated gene positioning and interchromosomal clustering at the nuclear periphery. J Cell Biol. 2016;212:633-46 pubmed publisher

Xia P, Ye B, Wang S, Zhu X, Du Y, Xiong Z, et al. Glutamylation of the DNA sensor cGAS regulates its binding and synthase activity in antiviral immunity. Nat Immunol. 2016;17:369-78 pubmed publisher

Wang R, Zhang Y, Kieffer M, Yu H, Kepinski S, Estelle M. HSP90 regulates temperature-dependent seedling growth in Arabidopsis by stabilizing the auxin co-receptor F-box protein TIR1. Nat Commun. 2016;7:10269 pubmed publisher

Qin J, Zhou Z, Chen W, Wang C, Zhang H, Ge G, et al. BAP1 promotes breast cancer cell proliferation and metastasis by deubiquitinating KLF5. Nat Commun. 2015;6:8471 pubmed publisher

Daou S, Hammond Martel I, Mashtalir N, Barbour H, Gagnon J, Iannantuono N, et al. The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer. J Biol Chem. 2015;290:28643-63 pubmed publisher

Dong L, Li L, Song Y, Duan Z, Sun S, Lin Y, et al. TRAF6-Mediated SM22α K21 Ubiquitination Promotes G6PD Activation and NADPH Production, Contributing to GSH Homeostasis and VSMC Survival In Vitro and In Vivo. Circ Res. 2015;117:684-94 pubmed publisher

Baker S, Lombardi L, Zoghbi H. Karyopherin α 3 and karyopherin α 4 proteins mediate the nuclear import of methyl-CpG binding protein 2. J Biol Chem. 2015;290:22485-93 pubmed publisher

Wang N, Zhang L, Chen Y, Lu Z, Gao L, Wang Y, et al. Cyclophilin A Interacts with Viral VP4 and Inhibits the Replication of Infectious Bursal Disease Virus. Biomed Res Int. 2015;2015:719454 pubmed publisher

Ge F, Chen W, Qin J, Zhou Z, Liu R, Liu L, et al. Ataxin-3 like (ATXN3L), a member of the Josephin family of deubiquitinating enzymes, promotes breast cancer proliferation by deubiquitinating Krüppel-like factor 5 (KLF5). Oncotarget. 2015;6:21369-78 pubmed

Amente S, Milazzo G, Sorrentino M, Ambrosio S, Di Palo G, Lania L, et al. Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively repress tumor suppressor genes in neuroblastoma. Oncotarget. 2015;6:14572-83 pubmed

Yu J, Ramasamy T, Murphy N, Holt M, Czapiewski R, Wei S, et al. PI3K/mTORC2 regulates TGF-β/Activin signalling by modulating Smad2/3 activity via linker phosphorylation. Nat Commun. 2015;6:7212 pubmed publisher

Wang C, Nie Z, Zhou Z, Zhang H, Liu R, Wu J, et al. The interplay between TEAD4 and KLF5 promotes breast cancer partially through inhibiting the transcription of p27Kip1. Oncotarget. 2015;6:17685-97 pubmed

Milenkovic A, Brandl C, Milenkovic V, Jendryke T, Sirianant L, Wanitchakool P, et al. Bestrophin 1 is indispensable for volume regulation in human retinal pigment epithelium cells. Proc Natl Acad Sci U S A. 2015;112:E2630-9 pubmed publisher

Xu D, Zhang T, Xiao J, Zhu K, Wei R, Wu Z, et al. Modification of BECN1 by ISG15 plays a crucial role in autophagy regulation by type I IFN/interferon. Autophagy. 2015;11:617-28 pubmed publisher

Dueck K, Hu Y, Chen P, Deschambault Y, Lee J, Varga J, et al. Mutational analysis of vaccinia virus E3 protein: the biological functions do not correlate with its biochemical capacity to bind double-stranded RNA. J Virol. 2015;89:5382-94 pubmed publisher

Baldeck N, Janel Bintz R, Wagner J, Tissier A, Fuchs R, Burkovics P, et al. FF483-484 motif of human Polη mediates its interaction with the POLD2 subunit of Polδ and contributes to DNA damage tolerance. Nucleic Acids Res. 2015;43:2116-25 pubmed publisher