This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Monosialoganglioside G M1 from bovine brain
catalog :
G7641
citations: 59
Reference
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Fujimura M, Usuki F. Methylmercury causes neuronal cell death through the suppression of the TrkA pathway: in vitro and in vivo effects of TrkA pathway activators. Toxicol Appl Pharmacol. 2015;282:259-66 pubmed publisher
Hadaczek P, Wu G, Sharma N, Ciesielska A, Bankiewicz K, Davidow A, et al. GDNF signaling implemented by GM1 ganglioside; failure in Parkinson's disease and GM1-deficient murine model. Exp Neurol. 2015;263:177-89 pubmed publisher
Ueno H, Yamaguchi T, Fukunaga S, Okada Y, Yano Y, Hoshino M, et al. Comparison between the aggregation of human and rodent amyloid β-proteins in GM1 ganglioside clusters. Biochemistry. 2014;53:7523-30 pubmed publisher
Yuki N, Yanaka C, Sudo M, Funakoshi M, Ishida H, Mori M, et al. Lower motor neuron syndrome associated with IgG anti-GM1 antibodies revisited. J Neuroimmunol. 2014;272:62-6 pubmed publisher
Puff N, Watanabe C, Seigneuret M, Angelova M, Staneva G. Lo/Ld phase coexistence modulation induced by GM1. Biochim Biophys Acta. 2014;1838:2105-14 pubmed publisher
Hong S, Ostaszewski B, Yang T, O Malley T, Jin M, Yanagisawa K, et al. Soluble A? oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes. Neuron. 2014;82:308-19 pubmed publisher
Domingue J, Rao M. CFTR and GM1 "gangl-ing" up to heal thy wound. Focus on "Reduced GM1 ganglioside in CFTR-deficient human airway cells results in decreased β1-integrin signaling and delayed wound repair". Am J Physiol Cell Physiol. 2014;306:C789-91 pubmed publisher
Kang S, Heo T, Kim S. Altered levels of α-synuclein and sphingolipids in Batten disease lymphoblast cells. Gene. 2014;539:181-5 pubmed publisher
Romero I, Garrido C, Algarra I, Collado A, Garrido F, Garcia Lora A. T lymphocytes restrain spontaneous metastases in permanent dormancy. Cancer Res. 2014;74:1958-68 pubmed publisher
Itokazu Y, Pagano R, Schroeder A, O Grady S, Limper A, Marks D. Reduced GM1 ganglioside in CFTR-deficient human airway cells results in decreased ?1-integrin signaling and delayed wound repair. Am J Physiol Cell Physiol. 2014;306:C819-30 pubmed publisher
Shrestha D, Exley M, Vereb G, Szollosi J, Jenei A. CD1d favors MHC neighborhood, GM1 ganglioside proximity and low detergent sensitive membrane regions on the surface of B lymphocytes. Biochim Biophys Acta. 2014;1840:667-80 pubmed
Mitsui Y, Kusunoki S, Arimura K, Kaji R, Kanda T, Kuwabara S, et al. A multicentre prospective study of Guillain-Barré syndrome in Japan: a focus on the incidence of subtypes. J Neurol Neurosurg Psychiatry. 2015;86:110-4 pubmed publisher
Novák J, Kriston Pál É, Czibula A, Deák M, Kovacs L, Monostori E, et al. GM1 controlled lateral segregation of tyrosine kinase Lck predispose T-cells to cell-derived galectin-1-induced apoptosis. Mol Immunol. 2014;57:302-9 pubmed publisher
Kuwabara S, Yuki N. Axonal Guillain-Barré syndrome: concepts and controversies. Lancet Neurol. 2013;12:1180-8 pubmed publisher
Cox C, Sharma M, Leckman J, Zuccolo J, Zuccolo A, Kovoor A, et al. Brain human monoclonal autoantibody from sydenham chorea targets dopaminergic neurons in transgenic mice and signals dopamine D2 receptor: implications in human disease. J Immunol. 2013;191:5524-41 pubmed publisher
Moeller S, Lau N, Green P, Hellberg D, Higgins J, Rajadhyaksha A, et al. Lack of association between autism and anti-GM1 ganglioside antibody. Neurology. 2013;81:1640-1 pubmed publisher
Pellistri F, Bucciantini M, Invernizzi G, Gatta E, Penco A, Frana A, et al. Different ataxin-3 amyloid aggregates induce intracellular Ca(2+) deregulation by different mechanisms in cerebellar granule cells. Biochim Biophys Acta. 2013;1833:3155-3165 pubmed publisher
Willison H, Galban Horcajo F, Halstead S. Antibodies to GM1: galactocerebroside complexes in multifocal motor neuropathy: it takes two to tango. J Neurol Neurosurg Psychiatry. 2014;85:715 pubmed publisher
Nobile Orazio E, Giannotta C, Musset L, Messina P, Leger J. Sensitivity and predictive value of anti-GM1/galactocerebroside IgM antibodies in multifocal motor neuropathy. J Neurol Neurosurg Psychiatry. 2014;85:754-8 pubmed publisher
Saslowsky D, te Welscher Y, Chinnapen D, Wagner J, Wan J, Kern E, et al. Ganglioside GM1-mediated transcytosis of cholera toxin bypasses the retrograde pathway and depends on the structure of the ceramide domain. J Biol Chem. 2013;288:25804-9 pubmed publisher
de Jong D, Lopez C, Marrink S. Molecular view on protein sorting into liquid-ordered membrane domains mediated by gangliosides and lipid anchors. Faraday Discuss. 2013;161:347-63; discussion 419-59 pubmed
Kreutz F, dos Santos Petry F, Camassola M, Schein V, Guma F, Nardi N, et al. Alterations of membrane lipids and in gene expression of ganglioside metabolism in different brain structures in a mouse model of mucopolysaccharidosis type I (MPS I). Gene. 2013;527:109-14 pubmed publisher
Vlasova I, Zakharova I, Sokolova T, Avrova N. [Metabolic effects of ganglioside GM1 on PC12 cells at oxidative stress depend on modulation of activity of tyrosine kinase of trk receptor]. Zh Evol Biokhim Fiziol. 2013;49:15-23 pubmed
Gustafsson T, Hua Y, Dahlgren M, Livingston M, Johansson Lindbom B, Yrlid U. Direct interaction between cholera toxin and dendritic cells is required for oral adjuvant activity. Eur J Immunol. 2013;43:1779-88 pubmed publisher
Willjes G, Mahrhold S, Strotmeier J, Eichner T, Rummel A, Binz T. Botulinum neurotoxin G binds synaptotagmin-II in a mode similar to that of serotype B: tyrosine 1186 and lysine 1191 cause its lower affinity. Biochemistry. 2013;52:3930-8 pubmed publisher
Gregory J, Topol A, Doerner D, Mayfield S. Alga-produced cholera toxin-Pfs25 fusion proteins as oral vaccines. Appl Environ Microbiol. 2013;79:3917-25 pubmed publisher
Wakerley B, Soon D, Chan Y, Yuki N. Atypical Bickerstaff brainstem encephalitis: ataxic hypersomnolence without ophthalmoplegia. J Neurol Neurosurg Psychiatry. 2013;84:1206-7 pubmed publisher
Calamai M, Pavone F. Partitioning and confinement of GM1 ganglioside induced by amyloid aggregates. FEBS Lett. 2013;587:1385-91 pubmed publisher
Sezgin E, Chwastek G, Aydogan G, Levental I, Simons K, Schwille P. Photoconversion of bodipy-labeled lipid analogues. Chembiochem. 2013;14:695-8 pubmed publisher
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Yamamoto N, Arima H, Sugiura T, Hirate H, Taniura H, Suzuki K, et al. Propofol and thiopental suppress amyloid fibril formation and GM1 ganglioside expression through the γ-aminobutyric acid A receptor. Anesthesiology. 2013;118:1408-16 pubmed publisher
Stergiou L, Bauer M, Mair W, Bausch Fluck D, Drayman N, Wollscheid B, et al. Integrin-mediated signaling induced by simian virus 40 leads to transient uncoupling of cortical actin and the plasma membrane. PLoS ONE. 2013;8:e55799 pubmed publisher
Zhu Y, Yang J, Jiao S, Ji T. Ganglioside-monosialic acid (GM1) prevents oxaliplatin-induced peripheral neurotoxicity in patients with gastrointestinal tumors. World J Surg Oncol. 2013;11:19 pubmed publisher
Benktander J, Angstrom J, Karlsson H, Teymournejad O, Lindén S, Lebens M, et al. The repertoire of glycosphingolipids recognized by Vibrio cholerae. PLoS ONE. 2013;8:e53999 pubmed publisher
Yamaguchi T, Uno T, Uekusa Y, Yagi Utsumi M, Kato K. Ganglioside-embedding small bicelles for probing membrane-landing processes of intrinsically disordered proteins. Chem Commun (Camb). 2013;49:1235-7 pubmed publisher
Matsubara T, Iijima K, Yamamoto N, Yanagisawa K, Sato T. Density of GM1 in nanoclusters is a critical factor in the formation of a spherical assembly of amyloid ?-protein on synaptic plasma membranes. Langmuir. 2013;29:2258-64 pubmed publisher
Willison H. The translation of the pathological findings described in humans to experimental models of acute motor axonal neuropathy. J Peripher Nerv Syst. 2012;17 Suppl 3:3-8 pubmed publisher
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Bibolini M, Julia Scerbo M, Peinetti N, Roth G, Monferran C. The hybrid between the ABC domains of synapsin and the B subunit of Escherichia coli heat-labile toxin ameliorates experimental autoimmune encephalomyelitis. Cell Immunol. 2012;280:50-60 pubmed publisher
Ryu J, Chang K, Lee J, Lim M, Min H, Na Y, et al. Ganglioside GM1 influences the proliferation rate of mouse induced pluripotent stem cells. BMB Rep. 2012;45:713-8 pubmed
Dobos J, Mohos A, Tovari J, Raso E, Lôrincz T, Zádori G, et al. Sex-dependent liver colonization of human melanoma in SCID mice--role of host defense mechanisms. Clin Exp Metastasis. 2013;30:497-506 pubmed publisher
Schneider J, Gollomp S, Sendek S, Colcher A, Cambi F, Du W. A randomized, controlled, delayed start trial of GM1 ganglioside in treated Parkinson's disease patients. J Neurol Sci. 2013;324:140-8 pubmed publisher
Miyazaki Y, Aoki M, Yano Y, Matsuzaki K. Interaction of antimicrobial peptide magainin 2 with gangliosides as a target for human cell binding. Biochemistry. 2012;51:10229-35 pubmed publisher
Huang J, Shao W, Wu L, Yang W, Chen Y. Effects of exogenous ganglioside GM1 on different stages of cell spreading studied by directly quantifying spreading rate. Cell Commun Adhes. 2012;19:85-95 pubmed publisher
Lammertse D. Clinical trials in spinal cord injury: lessons learned on the path to translation. The 2011 International Spinal Cord Society Sir Ludwig Guttmann Lecture. Spinal Cord. 2013;51:2-9 pubmed publisher
Kuwahara M, Suzuki H, Samukawa M, Hamada Y, Takada K, Kusunoki S. Clinical features of CIDP with LM1-associated antibodies. J Neurol Neurosurg Psychiatry. 2013;84:573-5 pubmed publisher
Nomura M, Shimbo T, Miyamoto Y, Fukuzawa M, Kaneda Y. 13-Cis retinoic acid can enhance the antitumor activity of non-replicating Sendai virus particle against neuroblastoma. Cancer Sci. 2013;104:238-44 pubmed publisher
Cheng Q, Li N, Chen M, Zheng J, Qian Z, Wang X, et al. Fuzheng Huayu inhibits carbon tetrachloride-induced liver fibrosis in mice through activating hepatic NK cells. J Ethnopharmacol. 2013;145:175-81 pubmed publisher
Staneva G, Puff N, Seigneuret M, Conjeaud H, Angelova M. Segregative clustering of Lo and Ld membrane microdomains induced by local pH gradients in GM1-containing giant vesicles: a lipid model for cellular polarization. Langmuir. 2012;28:16327-37 pubmed publisher
Jobling M, Yang Z, Kam W, Lencer W, Holmes R. A single native ganglioside GM1-binding site is sufficient for cholera toxin to bind to cells and complete the intoxication pathway. MBio. 2012;3: pubmed publisher
Li X, Han W, Boini K, Xia M, Zhang Y, Li P. TRAIL death receptor 4 signaling via lysosome fusion and membrane raft clustering in coronary arterial endothelial cells: evidence from ASM knockout mice. J Mol Med (Berl). 2013;91:25-36 pubmed publisher
Moeller L, Taylor Vokes R, Fox S, Gan Q, Johnson L, Wang K. Wet-milling transgenic maize seed for fraction enrichment of recombinant subunit vaccine. Biotechnol Prog. 2010;26:458-65 pubmed publisher
Moeller L, Gan Q, Wang K. A bacterial signal peptide is functional in plants and directs proteins to the secretory pathway. J Exp Bot. 2009;60:3337-52 pubmed publisher
product information
Catalog Number :
G7641
Product Name :
Monosialoganglioside G M1 from bovine brain
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥95%, lyophilized powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA