This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
β-Glucuronidase from Helix pomatia
catalog :
G7017
citations: 64
Reference
Gross M, Ploetz C, Gottschalk C. Immunochemical detection of mycotoxins in donkey milk. Mycotoxin Res. 2019;35:83-87 pubmed publisher
Houslay T, Earley R, Young A, Wilson A. Habituation and individual variation in the endocrine stress response in the Trinidadian guppy (Poecilia reticulata). Gen Comp Endocrinol. 2019;270:113-122 pubmed publisher
Kang M, Lin H. Systematic Evaluation and Validation of Benzodiazepines Confirmation Assay Using LC-MS-MS. J Anal Toxicol. 2019;43:96-103 pubmed publisher
Buscher B, van de Lagemaat D, Gries W, Beyer D, Markham D, Budinsky R, et al. Quantitative analysis of unconjugated and total bisphenol A in human urine using solid-phase extraction and UPLC-MS/MS: method implementation, method qualification and troubleshooting. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;1005:30-8 pubmed publisher
Derungs A, Donzelli M, Berger B, Noppen C, Krähenbühl S, Haschke M. Effects of Cytochrome P450 Inhibition and Induction on the Phenotyping Metrics of the Basel Cocktail: A Randomized Crossover Study. Clin Pharmacokinet. 2016;55:79-91 pubmed publisher
Ahtiainen J, Nyman K, Huhtaniemi I, Parviainen T, Helste M, Rannikko A, et al. Effects of resistance training on testosterone metabolism in younger and older men. Exp Gerontol. 2015;69:148-58 pubmed publisher
Paller C, Rudek M, Zhou X, Wagner W, Hudson T, Anders N, et al. A phase I study of muscadine grape skin extract in men with biochemically recurrent prostate cancer: Safety, tolerability, and dose determination. Prostate. 2015;75:1518-25 pubmed publisher
Wu Y, Zhang L, Na R, Xu J, Xiong Z, Zhang N, et al. Plasma genistein and risk of prostate cancer in Chinese population. Int Urol Nephrol. 2015;47:965-70 pubmed publisher
Scott A, Ellis T, Tveiten H. Identification of cortisol metabolites in the bile of Atlantic cod Gadus morhua L. Steroids. 2014;88:26-35 pubmed publisher
Ryzinska Paier G, Lendenfeld T, Correa K, Stadler P, Blaschke A, Mach R, et al. A sensitive and robust method for automated on-line monitoring of enzymatic activities in water and water resources. Water Sci Technol. 2014;69:1349-58 pubmed publisher
Hijova E, Szabadosová V, Strojny L, Bomba A. Changes chemopreventive markers in colorectal cancer development after inulin supplementation. Bratisl Lek Listy. 2014;115:76-9 pubmed
Lee J, Ahmad S, Roslan H. Transformation of Morinda citrifolia via simple mature seed imbibition method. Pak J Biol Sci. 2013;16:1913-21 pubmed
Higashi N, Waki M, Sue M, Kogane Y, Shida H, Tsunekawa N, et al. Heparanase-mediated cleavage of macromolecular heparin accelerates release of granular components of mast cells from extracellular matrices. Biochem J. 2014;458:291-9 pubmed publisher
Bramwell K, Ma Y, Weis J, Chen X, Zachary J, Teuscher C, et al. Lysosomal ?-glucuronidase regulates Lyme and rheumatoid arthritis severity. J Clin Invest. 2014;124:311-20 pubmed publisher
Matsubara T, Miyaki A, Akazawa N, Choi Y, Ra S, Tanahashi K, et al. Aerobic exercise training increases plasma Klotho levels and reduces arterial stiffness in postmenopausal women. Am J Physiol Heart Circ Physiol. 2014;306:H348-55 pubmed publisher
Ostrovsky O, Shimoni A, Baryakh P, Morgulis Y, Mayorov M, Beider K, et al. Modification of heparanase gene expression in response to conditioning and LPS treatment: strong correlation to rs4693608 SNP. J Leukoc Biol. 2014;95:677-88 pubmed publisher
Wilson J, Laloo A, Singh S, Ferro V. 1H NMR spectroscopic studies establish that heparanase is a retaining glycosidase. Biochem Biophys Res Commun. 2014;443:185-8 pubmed publisher
Gattineni J, Alphonse P, Zhang Q, Mathews N, Bates C, Baum M. Regulation of renal phosphate transport by FGF23 is mediated by FGFR1 and FGFR4. Am J Physiol Renal Physiol. 2014;306:F351-8 pubmed publisher
Parker E, Xing M, Moreno De Luca A, Harmouche E, Terk M. Radiological and clinical characterization of the lysosomal storage disorders: non-lipid disorders. Br J Radiol. 2014;87:20130467 pubmed publisher
Tucker Zhou T, King G, Chen C, Abraham C. Biochemical and functional characterization of the klotho-VS polymorphism implicated in aging and disease risk. J Biol Chem. 2013;288:36302-11 pubmed publisher
Xie F, Peng Y, Chen X, Chen X, Li J, Wang W, et al. Relationship between the expression of CES2, UGT1A1, and GUSB in colorectal cancer tissues and aberrant methylation. Neoplasma. 2014;61:99-109 pubmed
Zaza G, Masola V, Granata S, Pontrelli P, Sallustio F, Gesualdo L, et al. Dialysis-related transcriptomic profiling: the pivotal role of heparanase. Exp Biol Med (Maywood). 2014;239:52-64 pubmed publisher
Navarro González J, Donate Correa J, Muros de Fuentes M, Pérez Hernández H, Martinez Sanz R, Mora Fernández C. Reduced Klotho is associated with the presence and severity of coronary artery disease. Heart. 2014;100:34-40 pubmed publisher
Hong Y, Choi D, Lim S, Yang C, Chang Y. Decreased parathyroid Klotho expression is associated with persistent hyperparathyroidism after kidney transplantation. Transplant Proc. 2013;45:2957-62 pubmed publisher
Kinkema M, Geijskes R, Shand K, Coleman H, De Lucca P, Palupe A, et al. An improved chemically inducible gene switch that functions in the monocotyledonous plant sugar cane. Plant Mol Biol. 2014;84:443-54 pubmed publisher
Aguilar Hernandez V, Guzman P. The fate of tandemly duplicated genes assessed by the expression analysis of a group of Arabidopsis thaliana RING-H2 ubiquitin ligase genes of the ATL family. Plant Mol Biol. 2014;84:429-41 pubmed publisher
Dërmaku Sopjani M, Kolgeci S, Abazi S, Sopjani M. Significance of the anti-aging protein Klotho. Mol Membr Biol. 2013;30:369-85 pubmed publisher
Zhang D, Wan A, Chiu A, Wang Y, Wang F, Neumaier K, et al. Hyperglycemia-induced secretion of endothelial heparanase stimulates a vascular endothelial growth factor autocrine network in cardiomyocytes that promotes recruitment of lipoprotein lipase. Arterioscler Thromb Vasc Biol. 2013;33:2830-8 pubmed publisher
Tan K, Chong S, Wong F, Evrard M, Tan S, Keeble J, et al. Neutrophils contribute to inflammatory lymphangiogenesis by increasing VEGF-A bioavailability and secreting VEGF-D. Blood. 2013;122:3666-77 pubmed publisher
Kokkinaki M, Abu Asab M, Gunawardena N, Ahern G, Javidnia M, Young J, et al. Klotho regulates retinal pigment epithelial functions and protects against oxidative stress. J Neurosci. 2013;33:16346-59 pubmed publisher
Schmid C, Neidert M, Tschopp O, Sze L, Bernays R. Growth hormone and Klotho. J Endocrinol. 2013;219:R37-57 pubmed publisher
Song W, Sun H, Li J, Gong X, Huang S, Zhu X, et al. Auxin distribution is differentially affected by nitrate in roots of two rice cultivars differing in responsiveness to nitrogen. Ann Bot. 2013;112:1383-93 pubmed publisher
Liu Y, Ding G, Li Y, Qu J, Ma S, Lv H, et al. Structures and absolute configurations of penicillactones A-C from an endophytic microorganism, Penicillium dangeardii Pitt. Org Lett. 2013;15:5206-9 pubmed publisher
Imura A. [Updates on rickets and osteomalacia: various roles of Klotho and FGF23 in vivo ]. Clin Calcium. 2013;23:1476-82 pubmed publisher
Emets A, Boĭchuk I, Shisha E, Rakhmetov D, Blium I. [Establishment of in vitro culture, plant regeneration and genetic transformation of Camelina sativa]. Tsitol Genet. 2013;47:14-20 pubmed
GUTIERREZ O, Ix J. α-Klotho and kidney function decline: an important step forward in understanding the link between mineral metabolism and kidney disease progression. Am J Kidney Dis. 2013;61:855-7 pubmed publisher
Hu G, Yuan Y, Wu C, Jiang C, Wang Z, Lin S, et al. [Effect of different developmental stage on plant growth and active compounds in Scutellaria baicalensis]. Zhongguo Zhong Yao Za Zhi. 2012;37:3793-8 pubmed
Guo Z, Cui T, Xue J, Zhu Y, Zhang A, Sheng W, et al. [Genetic transformation of Pinellia ternata with Agrobacterium tumefaciens-mediated sHSP genes]. Zhongguo Zhong Yao Za Zhi. 2012;37:3758-62 pubmed
Pratibha P, Singh S, Sharma I, Kumar R, Srinivasan R, Bhat S, et al. Characterization of a T-DNA promoter trap line of Arabidopsis thaliana uncovers a cryptic bi-directional promoter. Gene. 2013;524:22-7 pubmed publisher
Munoz C, Pakladok T, Almilaji A, Elvira B, Seebohm G, Voelkl J, et al. Klotho sensitivity of the hERG channel. FEBS Lett. 2013;587:1663-8 pubmed publisher
Sanchez Niño M, Sanz A, Ortiz A. Klotho to treat kidney fibrosis. J Am Soc Nephrol. 2013;24:687-9 pubmed publisher
Zhou L, Li Y, Zhou D, Tan R, Liu Y. Loss of Klotho contributes to kidney injury by derepression of Wnt/?-catenin signaling. J Am Soc Nephrol. 2013;24:771-85 pubmed publisher
Kim H, Nam B, Kim D, Kang M, Han J, Lee M, et al. Circulating α-klotho levels in CKD and relationship to progression. Am J Kidney Dis. 2013;61:899-909 pubmed publisher
Modick H, Schütze A, Pälmke C, Weiss T, Bruning T, Koch H. Rapid determination of N-acetyl-4-aminophenol (paracetamol) in urine by tandem mass spectrometry coupled with on-line clean-up by two dimensional turbulent flow/reversed phase liquid chromatography. J Chromatogr B Analyt Technol Biomed Life Sci. 2013;925:33-9 pubmed publisher
Liu X, Fang H, Zhu D, Zhang Y. [Construction of a lentiviral RNA interference system targeting heparanase based on miR30 and its silencing effect]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2013;42:67-74 pubmed
Gao Y, Liu J, Zhang Z, Sun X, Zhang N, Fan J, et al. Functional characterization of two alternatively spliced transcripts of tomato ABSCISIC ACID INSENSITIVE3 (ABI3) gene. Plant Mol Biol. 2013;82:131-45 pubmed publisher
Riaz A, Ilan N, Vlodavsky I, Li J, Johansson S. Characterization of heparanase-induced phosphatidylinositol 3-kinase-AKT activation and its integrin dependence. J Biol Chem. 2013;288:12366-75 pubmed publisher
Zhang Y, Wang N, Raab R, McKown R, Irwin J, Kwon I, et al. Targeting of heparanase-modified syndecan-1 by prosecretory mitogen lacritin requires conserved core GAGAL plus heparan and chondroitin sulfate as a novel hybrid binding site that enhances selectivity. J Biol Chem. 2013;288:12090-101 pubmed publisher
Wang Y, Zhang D, Chiu A, Wan A, Neumaier K, Vlodavsky I, et al. Endothelial heparanase regulates heart metabolism by stimulating lipoprotein lipase secretion from cardiomyocytes. Arterioscler Thromb Vasc Biol. 2013;33:894-902 pubmed publisher
Cassinelli G, Lanzi C, Tortoreto M, Cominetti D, Petrangolini G, Favini E, et al. Antitumor efficacy of the heparanase inhibitor SST0001 alone and in combination with antiangiogenic agents in the treatment of human pediatric sarcoma models. Biochem Pharmacol. 2013;85:1424-32 pubmed publisher
Touchberry C, Green T, Tchikrizov V, Mannix J, Mao T, Carney B, et al. FGF23 is a novel regulator of intracellular calcium and cardiac contractility in addition to cardiac hypertrophy. Am J Physiol Endocrinol Metab. 2013;304:E863-73 pubmed publisher
Hálová I, Dráberová L, Bambousková M, Machyna M, Stegurová L, Smrz D, et al. Cross-talk between tetraspanin CD9 and transmembrane adaptor protein non-T cell activation linker (NTAL) in mast cell activation and chemotaxis. J Biol Chem. 2013;288:9801-14 pubmed publisher
Feng S, Dakhova O, Creighton C, Ittmann M. Endocrine fibroblast growth factor FGF19 promotes prostate cancer progression. Cancer Res. 2013;73:2551-62 pubmed publisher
Zhu Y, Xu L, Zhang J, Xu W, Liu Y, Yin H, et al. Klotho suppresses tumor progression via inhibiting PI3K/Akt/GSK3?/Snail signaling in renal cell carcinoma. Cancer Sci. 2013;104:663-71 pubmed publisher
Thompson C, Purushothaman A, Ramani V, Vlodavsky I, Sanderson R. Heparanase regulates secretion, composition, and function of tumor cell-derived exosomes. J Biol Chem. 2013;288:10093-9 pubmed publisher
Song F, Cui C, Chen L, Sun Y, Wang F, Hussain J, et al. Isolation and characterization of an endosperm-specific promoter from wheat (Triticum aestivum L.). Z Naturforsch C J Biosci. 2012;67:611-9 pubmed
Goetz R, Mohammadi M. Exploring mechanisms of FGF signalling through the lens of structural biology. Nat Rev Mol Cell Biol. 2013;14:166-80 pubmed publisher
Meirovitz A, Goldberg R, Binder A, Rubinstein A, Hermano E, Elkin M. Heparanase in inflammation and inflammation-associated cancer. FEBS J. 2013;280:2307-19 pubmed publisher
Ye X, Guo Y, Zhang Q, Chen W, Hua X, Liu W, et al. ?Klotho suppresses tumor growth in hepatocellular carcinoma by regulating Akt/GSK-3?/cyclin D1 signaling pathway. PLoS ONE. 2013;8:e55615 pubmed publisher
Matsushita Oikawa H, Komatsu M, Iida Tanaka N, Sakagami H, Kanamori T, Matsumoto I, et al. Novel carbohydrate-binding activity of bovine liver beta-glucuronidase toward lactose/N-acetyllactosamine sequences. Glycobiology. 2006;16:891-901 pubmed
Xing J, Chen X, Zhong D. Stability of baicalin in biological fluids in vitro. J Pharm Biomed Anal. 2005;39:593-600 pubmed
Fishman W. [Not Available]. Adv Enzymol Relat Subj Biochem. 1955;16:361-409 pubmed
Wakabayashi M, Fishman W. The comparative ability of beta-glucuronidase preparations (liver, Escherichia coli, Helix pomatia, and Patella vulgata) to hydrolyze certain steroid glucosiduronic acids. J Biol Chem. 1961;236:996-1001 pubmed
Doyle M, Katzman P, Doisy E. Production and properties of bacterial beta-glucuronidase. J Biol Chem. 1955;217:921-30 pubmed
product information
Catalog Number :
G7017
Product Name :
β-Glucuronidase from Helix pomatia
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
Type HP-2, aqueous solution, ?100,000 units/mL
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA