This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
GW7647
catalog :
G6793
citations: 25
Reference
Liu Y, Izem L, Morton R. Identification of a hormone response element that mediates suppression of APOF by LXR and PPARα agonists. Biochim Biophys Acta Mol Cell Biol Lipids. 2020;1865:158583 pubmed publisher
Fujimori K, Iguchi Y, Yamashita Y, Gohda K, Teno N. Synthesis of Novel Farnesoid X Receptor Agonists and Validation of Their Efficacy in Activating Differentiation of Mouse Bone Marrow-Derived Mesenchymal Stem Cells into Osteoblasts. Molecules. 2019;24: pubmed publisher
Huan Y, Pan X, Peng J, Jia C, Sun S, Bai G, et al. A novel specific peroxisome proliferator-activated receptor γ (PPARγ) modulator YR4-42 ameliorates hyperglycaemia and dyslipidaemia and hepatic steatosis in diet-induced obese mice. Diabetes Obes Metab. 2019;21:2553-2563 pubmed publisher
Guo S, Som A, Arai K, Lo E. Effects of angiotensin-II on brain endothelial cell permeability via PPARalpha regulation of para- and trans-cellular pathways. Brain Res. 2019;1722:146353 pubmed publisher
Nogueira Recalde U, Lorenzo Gómez I, Blanco F, Loza M, Grassi D, Shirinsky V, et al. Fibrates as drugs with senolytic and autophagic activity for osteoarthritis therapy. EBioMedicine. 2019;45:588-605 pubmed publisher
Hwang J, So Y, Bae G, Kim S, Kim Y. Protein arginine methyltransferase 6 suppresses adipogenic differentiation by repressing peroxisome proliferator‑activated receptor γ activity. Int J Mol Med. 2019;43:2462-2470 pubmed publisher
Luckert C, Braeuning A, Lampen A, Hessel Pras S. PXR: Structure-specific activation by hepatotoxic pyrrolizidine alkaloids. Chem Biol Interact. 2018;288:38-48 pubmed publisher
Ord T, Ord D, Ord T. TRIB3 limits FGF21 induction during in vitro and in vivo nutrient deficiencies by inhibiting C/EBP-ATF response elements in the Fgf21 promoter. Biochim Biophys Acta Gene Regul Mech. 2018;1861:271-281 pubmed publisher
Valanejad L, Ghareeb M, Shiffka S, Nadolny C, Chen Y, Guo L, et al. Dysregulation of Δ4-3-oxosteroid 5β-reductase in diabetic patients: Implications and mechanisms. Mol Cell Endocrinol. 2018;470:127-141 pubmed publisher
Cheng Y, Wei Z, Xie S, Peng Y, Yan Y, Qin D, et al. Alleviation of Toxicity Caused by Overactivation of Ppar? through Ppar?-Inducible miR-181a2. Mol Ther Nucleic Acids. 2017;9:195-206 pubmed publisher
Wu J, Wang J, Liu T, Zhou Y, Qiu C, Shen D, et al. PPAR-? acutely inhibits functional activity of ASICs in rat dorsal root ganglion neurons. Oncotarget. 2017;8:93051-93062 pubmed publisher
Vergori L, Lauret E, Soleti R, Andriantsitohaina R, Carmen Martínez M. Microparticles Carrying Peroxisome Proliferator-Activated Receptor Alpha Restore the Reduced Differentiation and Functionality of Bone Marrow-Derived Cells Induced by High-Fat Diet. Stem Cells Transl Med. 2017;: pubmed publisher
Kim Y, Hwang S, Jia Y, Seo W, Lee S. Barley sprout extracts reduce hepatic lipid accumulation in ethanol-fed mice by activating hepatic AMP-activated protein kinase. Food Res Int. 2017;101:209-217 pubmed publisher
Petta I, Bougarne N, Vandewalle J, Dejager L, Vandevyver S, Ballegeer M, et al. Glucocorticoid Receptor-mediated transactivation is hampered by Striatin-3, a novel interaction partner of the receptor. Sci Rep. 2017;7:8941 pubmed publisher
Zhang J, Wang X, Liu X, Huan Y, Yang M, Shen Z, et al. Design, sythesis and evaluation of a series of 3- or 4-alkoxy substituted phenoxy derivatives as PPARs agonists. Oncotarget. 2017;8:20766-20783 pubmed publisher
van der Krieken S, Popeijus H, Konings M, Dullens S, Mensink R, Plat J. C/EBP-β Is Differentially Affected by PPARα Agonists Fenofibric Acid and GW7647, But Does Not Change Apolipoprotein A-I Production During ER-Stress and Inflammation. J Cell Biochem. 2017;118:754-763 pubmed publisher
He P, Li Y, Ding X, Sun Q, Huang Y, Gu H, et al. Expression of 15-Hydroxyprostaglandin Dehydrogenase in Human Chorion Is Associated with Peroxisome Proliferator-Activated Receptor Isoform Expression in Term Labor. Am J Pathol. 2015;185:1981-90 pubmed publisher
Martinez A, Morgese M, Pisanu A, Macheda T, Paquette M, Seillier A, et al. Activation of PPAR gamma receptors reduces levodopa-induced dyskinesias in 6-OHDA-lesioned rats. Neurobiol Dis. 2015;74:295-304 pubmed publisher
Langhi C, Baldán Ã. CIDEC/FSP27 is regulated by peroxisome proliferator-activated receptor alpha and plays a critical role in fasting- and diet-induced hepatosteatosis. Hepatology. 2015;61:1227-38 pubmed publisher
Tanner L, Chng C, Guan X, Lei Z, Rozen S, Wenk M. Lipidomics identifies a requirement for peroxisomal function during influenza virus replication. J Lipid Res. 2014;55:1357-65 pubmed publisher
Cyphert H, Alonge K, Ippagunta S, Hillgartner F. Glucagon stimulates hepatic FGF21 secretion through a PKA- and EPAC-dependent posttranscriptional mechanism. PLoS ONE. 2014;9:e94996 pubmed publisher
Masoodi M, Lee E, Eiden M, Bahlo A, Shi Y, Ceddia R, et al. A role for oleoylethanolamide in chronic lymphocytic leukemia. Leukemia. 2014;28:1381-7 pubmed publisher
Gregoire F, Zhang F, Clarke H, Gustafson T, SEARS D, Favelyukis S, et al. MBX-102/JNJ39659100, a novel peroxisome proliferator-activated receptor-ligand with weak transactivation activity retains antidiabetic properties in the absence of weight gain and edema. Mol Endocrinol. 2009;23:975-88 pubmed publisher
Ramanan S, Kooshki M, Zhao W, Hsu F, Robbins M. PPARalpha ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-kappaB and AP-1 pathways. Free Radic Biol Med. 2008;45:1695-704 pubmed publisher
Mazzucotelli A, Viguerie N, Tiraby C, Annicotte J, Mairal A, Klimcakova E, et al. The transcriptional coactivator peroxisome proliferator activated receptor (PPAR)gamma coactivator-1 alpha and the nuclear receptor PPAR alpha control the expression of glycerol kinase and metabolism genes independently of PPAR gamma activation in hu. Diabetes. 2007;56:2467-75 pubmed
product information
Catalog Number :
G6793
Product Name :
GW7647
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥98% (HPLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA