Klement P, Carlsson S, Rak J, Liao P, Vlasin M, Stafford A, et al. The benefit-to-risk profile of melagatran is superior to that of hirudin in a rabbit arterial thrombosis prevention and bleeding model. J Thromb Haemost. 2003;1:587-94 pubmed

Cho M, Pestina T, Steward S, Lowell C, Jackson C, Gartner T. Role of the Src family kinase Lyn in TxA2 production, adenosine diphosphate secretion, Akt phosphorylation, and irreversible aggregation in platelets stimulated with gamma-thrombin. Blood. 2002;99:2442-7 pubmed

Liaw P, Becker D, Stafford A, Fredenburgh J, Weitz J. Molecular basis for the susceptibility of fibrin-bound thrombin to inactivation by heparin cofactor ii in the presence of dermatan sulfate but not heparin. J Biol Chem. 2001;276:20959-65 pubmed

Pratt K, Côté H, Chung D, Stenkamp R, Davie E. The primary fibrin polymerization pocket: three-dimensional structure of a 30-kDa C-terminal gamma chain fragment complexed with the peptide Gly-Pro-Arg-Pro. Proc Natl Acad Sci U S A. 1997;94:7176-81 pubmed

Yamazumi K, Doolittle R. The synthetic peptide Gly-Pro-Arg-Pro-amide limits the plasmic digestion of fibrinogen in the same fashion as calcium ion. Protein Sci. 1992;1:1719-20 pubmed

Kawasaki K, Hirase K, Miyano M, Tsuji T, Iwamoto M. Amino acids and peptides. XVI. Synthesis of N-terminal tetrapeptide analogs of fibrin alpha-chain and their inhibitory effects on fibrinogen/thrombin clotting. Chem Pharm Bull (Tokyo). 1992;40:3253-60 pubmed