product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-Gelsolin antibody produced in mouse
catalog :
G4896
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
GS-2C4
reactivity :
human
application :
western blot
more info or order :
citations: 27
Published Application/Species/Sample/DilutionReference
  • western blot; human
Henriques A, Oliveira J, Gomes B, Ruivo R, da Cruz e Silva E, da Cruz e Silva O. Complexing A? prevents the cellular anomalies induced by the Peptide alone. J Mol Neurosci. 2014;53:661-8 pubmed publisher
Watek M, Wnorowska U, Wollny T, Durnás B, Wolak P, Kościołek Zgódka S, et al. Hypogelsolinemia in Patients Diagnosed with Acute Myeloid Leukemia at Initial Stage of Sepsis. Med Sci Monit. 2019;25:1452-1458 pubmed publisher
Boussadia Z, Lamberti J, Mattei F, Pizzi E, Puglisi R, Zanetti C, et al. Acidic microenvironment plays a key role in human melanoma progression through a sustained exosome mediated transfer of clinically relevant metastatic molecules. J Exp Clin Cancer Res. 2018;37:245 pubmed publisher
Kim J, Ha Y, Tak K, Roh S, Kwon Y, Kim C, et al. Opposite functions of GSN and OAS2 on colorectal cancer metastasis, mediating perineural and lymphovascular invasion, respectively. PLoS ONE. 2018;13:e0202856 pubmed publisher
Chen C, Chiou S, Yang C, Chow K, Lin T, Chang H, et al. Secreted gelsolin desensitizes and induces apoptosis of infiltrated lymphocytes in prostate cancer. Oncotarget. 2017;8:77152-77167 pubmed publisher
Zhao L, Liu J, He C, Yan R, Zhou K, Cui Q, et al. Protein kinase A determines platelet life span and survival by regulating apoptosis. J Clin Invest. 2017;127:4338-4351 pubmed publisher
Marsh L, Carrera S, Shandilya J, Heesom K, Davidson A, Medler K, et al. BASP1 interacts with oestrogen receptor α and modifies the tamoxifen response. Cell Death Dis. 2017;8:e2771 pubmed publisher
Argun M, Baykan A, Narin F, Ozyurt A, Pamukcu O, Elmali F, et al. Plasma gelsolin as a biomarker of acute rheumatic carditis. Cardiol Young. 2015;25:1276-80 pubmed publisher
Al Gubory K, Arianmanesh M, Garrel C, Bhattacharya S, Cash P, Fowler P. Proteomic analysis of the sheep caruncular and intercaruncular endometrium reveals changes in functional proteins crucial for the establishment of pregnancy. Reproduction. 2014;147:599-614 pubmed publisher
Yuan X, Yu L, Li J, Xie G, Rong T, Zhang L, et al. ATF3 suppresses metastasis of bladder cancer by regulating gelsolin-mediated remodeling of the actin cytoskeleton. Cancer Res. 2013;73:3625-37 pubmed publisher
Megger D, Bracht T, Kohl M, Ahrens M, Naboulsi W, Weber F, et al. Proteomic differences between hepatocellular carcinoma and nontumorous liver tissue investigated by a combined gel-based and label-free quantitative proteomics study. Mol Cell Proteomics. 2013;12:2006-20 pubmed publisher
Baig R, Mahjabeen I, Sabir M, Masood N, Ali K, Malik F, et al. Mutational spectrum of Gelsolin and its down regulation is associated with breast cancer. Dis Markers. 2013;34:71-80 pubmed publisher
Grau L, Luque Garcia J, Gonzalez Peramato P, Theodorescu D, Palou J, Fernández Gómez J, et al. A quantitative proteomic analysis uncovers the relevance of CUL3 in bladder cancer aggressiveness. PLoS ONE. 2013;8:e53328 pubmed publisher
Li G, Arora P, Chen Y, McCulloch C, Liu P. Multifunctional roles of gelsolin in health and diseases. Med Res Rev. 2012;32:999-1025 pubmed publisher
Sollberger G, Strittmatter G, Kistowska M, French L, Beer H. Caspase-4 is required for activation of inflammasomes. J Immunol. 2012;188:1992-2000 pubmed publisher
Kułakowska A, Ciccarelli N, Wen Q, Mroczko B, Drozdowski W, Szmitkowski M, et al. Hypogelsolinemia, a disorder of the extracellular actin scavenger system, in patients with multiple sclerosis. BMC Neurol. 2010;10:107 pubmed publisher
Güntert A, Campbell J, Saleem M, O Brien D, Thompson A, Byers H, et al. Plasma gelsolin is decreased and correlates with rate of decline in Alzheimer's disease. J Alzheimers Dis. 2010;21:585-96 pubmed publisher
Keller M, Sollberger G, Beer H. Thalidomide inhibits activation of caspase-1. J Immunol. 2009;183:5593-9 pubmed publisher
Papasavvas E, Pistilli M, Reynolds G, Bucki R, Azzoni L, Chehimi J, et al. Delayed loss of control of plasma lipopolysaccharide levels after therapy interruption in chronically HIV-1-infected patients. AIDS. 2009;23:369-75 pubmed publisher
Hao J, Wang G, Pisitkun T, Patino Lopez G, Nagashima K, Knepper M, et al. Enrichment of distinct microfilament-associated and GTP-binding-proteins in membrane/microvilli fractions from lymphoid cells. J Proteome Res. 2008;7:2911-27 pubmed publisher
Ikeda M, Mizushima K, Fujita Y, Watanabe M, Sasaki A, Makioka K, et al. Familial amyloid polyneuropathy (Finnish type) in a Japanese family: Clinical features and immunocytochemical studies. J Neurol Sci. 2007;252:4-8 pubmed
Park S, Hwang I, Kim S, Lee S, Park K, Lee S. Characterization of plasma gelsolin as a substrate for matrix metalloproteinases. Proteomics. 2006;6:1192-9 pubmed
Harris E, Li F, Higgs H. The mouse formin, FRLalpha, slows actin filament barbed end elongation, competes with capping protein, accelerates polymerization from monomers, and severs filaments. J Biol Chem. 2004;279:20076-87 pubmed
Kwik J, Boyle S, Fooksman D, Margolis L, Sheetz M, Edidin M. Membrane cholesterol, lateral mobility, and the phosphatidylinositol 4,5-bisphosphate-dependent organization of cell actin. Proc Natl Acad Sci U S A. 2003;100:13964-9 pubmed
Kiuru S. Gelsolin-related familial amyloidosis, Finnish type (FAF), and its variants found worldwide. Amyloid. 1998;5:55-66 pubmed
Kurokawa H, Fujii W, Ohmi K, Sakurai T, Nonomura Y. Simple and rapid purification of brevin. Biochem Biophys Res Commun. 1990;168:451-7 pubmed
Haltia M, Prelli F, Ghiso J, Kiuru S, Somer H, Palo J, et al. Amyloid protein in familial amyloidosis (Finnish type) is homologous to gelsolin, an actin-binding protein. Biochem Biophys Res Commun. 1990;167:927-32 pubmed
product information
Catalog Number :
G4896
Product Name :
Monoclonal Anti-Gelsolin antibody produced in mouse
Product Type :
ANTIBODIES - SIAL
Product Group :
Protein & Pathway Technologies
Host Species :
mouse
Clonality :
monoclonal
Conjugation :
unconjugated
Clone Name :
GS-2C4
Isotype :
IgG1
Product Description :
clone GS-2C4, ascites fluid
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA