This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Gly-Arg-Gly-Asp-Ser
catalog :
G4391
citations: 46
Reference
Gong H, Park J, Kim W, Kim J, Lee J, Koh W. A Novel Conductive and Micropatterned PEG-Based Hydrogel Enabling the Topographical and Electrical Stimulation of Myoblasts. ACS Appl Mater Interfaces. 2019;11:47695-47706 pubmed publisher
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Kamsma D, Bochet P, Oswald F, Alblas N, Goyard S, Wuite G, et al. Single-Cell Acoustic Force Spectroscopy: Resolving Kinetics and Strength of T Cell Adhesion to Fibronectin. Cell Rep. 2018;24:3008-3016 pubmed publisher
O Neill P, Castillo Badillo J, Meshik X, Kalyanaraman V, Melgarejo K, Gautam N. Membrane Flow Drives an Adhesion-Independent Amoeboid Cell Migration Mode. Dev Cell. 2018;46:9-22.e4 pubmed publisher
Osawa S, Kurachi M, Yamamoto H, Yoshimoto Y, Ishizaki Y. Fibronectin on extracellular vesicles from microvascular endothelial cells is involved in the vesicle uptake into oligodendrocyte precursor cells. Biochem Biophys Res Commun. 2017;488:232-238 pubmed publisher
Parviz M, Gaus K, Gooding J. Simultaneous impedance spectroscopy and fluorescence microscopy for the real-time monitoring of the response of cells to drugs. Chem Sci. 2017;8:1831-1840 pubmed publisher
Yun D, Lee Y, Laughter M, Freed C, Park D. Substantial Differentiation of Human Neural Stem Cells Into Motor Neurons on a Biomimetic Polyurea. Macromol Biosci. 2015;15:1206-11 pubmed publisher
Zhang Y, Ge C, Zhu C, Salaita K. DNA-based digital tension probes reveal integrin forces during early cell adhesion. Nat Commun. 2014;5:5167 pubmed publisher
Hoekman J, Srivastava P, Ho R. Aerosol-stable peptide-coated liposome nanoparticles: a proof-of-concept study with opioid fentanyl in enhancing analgesic effects and reducing plasma drug exposure. J Pharm Sci. 2014;103:2231-9 pubmed publisher
Flannagan R, Canton J, Furuya W, Glogauer M, Grinstein S. The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis. Mol Biol Cell. 2014;25:1511-22 pubmed publisher
Hansson A, Di Francesco T, Falson F, Rousselle P, Jordan O, Borchard G. Preparation and evaluation of nanoparticles for directed tissue engineering. Int J Pharm. 2012;439:73-80 pubmed publisher
Hansson A, Hashom N, Falson F, Rousselle P, Jordan O, Borchard G. In vitro evaluation of an RGD-functionalized chitosan derivative for enhanced cell adhesion. Carbohydr Polym. 2012;90:1494-500 pubmed publisher
Khraiche M, Muthuswamy J. Multi-modal biochip for simultaneous, real-time measurement of adhesion and electrical activity of neurons in culture. Lab Chip. 2012;12:2930-41 pubmed publisher
Aizawa Y, Shoichet M. The role of endothelial cells in the retinal stem and progenitor cell niche within a 3D engineered hydrogel matrix. Biomaterials. 2012;33:5198-205 pubmed publisher
Wang W, Liu Y, Wang J, Yuan Z, Kong D. The potential for blood vessel engineering of PHSRN-modified polymer: HUVEC cell affinity evaluation and integrin-mediated mechanism study. J Control Release. 2011;152 Suppl 1:e243-5 pubmed publisher
Xu Z, Li T, Zhong Z, Zha D, Wu S, Liu F, et al. Amide-linkage formed between ammonia plasma treated poly(D,L-lactide acid) scaffolds and bio-peptides: enhancement of cell adhesion and osteogenic differentiation in vitro. Biopolymers. 2011;95:682-94 pubmed publisher
Xu Z, Chen J, Li T, Zha D, Zhang X, Jiang X, et al. [Effects of bioactive modification of poly-D,L-lactide acid scaffolds on the biological behaviors of the seed cells]. Nan Fang Yi Ke Da Xue Xue Bao. 2011;31:289-94 pubmed
Joy A, Cohen D, Luk A, Anim Danso E, Chen C, Kohn J. Control of surface chemistry, substrate stiffness, and cell function in a novel terpolymer methacrylate library. Langmuir. 2011;27:1891-9 pubmed publisher
Swildens J, de Vries A, Li Z, Umar S, Atsma D, Schalij M, et al. Integrin stimulation favors uptake of macromolecules by cardiomyocytes in vitro. Cell Physiol Biochem. 2010;26:999-1010 pubmed publisher
Liu Y, Wang W, Wang J, Yuan Z, Tang S, Liu M, et al. HUVEC cell affinity evaluation and integrin-mediated mechanism study on PHSRN-modified polymer. Colloids Surf B Biointerfaces. 2011;84:6-12 pubmed publisher
Cho H, Gao H, Srinivasan A, Hong J, Bencherif S, Siegwart D, et al. Rapid cellular internalization of multifunctional star polymers prepared by atom transfer radical polymerization. Biomacromolecules. 2010;11:2199-203 pubmed publisher
Bockelmann J, Klinkhammer K, von Holst A, Seiler N, Faissner A, Brook G, et al. Functionalization of electrospun poly(?-caprolactone) fibers with the extracellular matrix-derived peptide GRGDS improves guidance of schwann cell migration and axonal growth. Tissue Eng Part A. 2011;17:475-86 pubmed publisher
Petershans A, Lyapin A, Reichlmaier S, Kalinina S, Wedlich D, Gliemann H. TOF-SIMS analysis of structured surfaces biofunctionalized by a one-step coupling of a spacer-linked GRGDS peptide. J Colloid Interface Sci. 2010;341:30-7 pubmed publisher
Liu Y, Wang W, Wang J, Wang Y, Yuan Z, Tang S, et al. Blood compatibility evaluation of poly(D,L-lactide-co-beta-malic acid) modified with the GRGDS sequence. Colloids Surf B Biointerfaces. 2010;75:370-6 pubmed publisher
Kim H, Kang W, Jeon E, Jang J. Construction and expression of a recombinant fibronectinIII10 protein for integrin-mediated cell adhesion. Biotechnol Lett. 2010;32:29-33 pubmed publisher
Gebauer J, Keene D, Olsen B, Sorokin L, Paulsson M, Wagener R. Mouse AMACO, a kidney and skin basement membrane associated molecule that mediates RGD-dependent cell attachment. Matrix Biol. 2009;28:456-62 pubmed publisher
Ohashi R, Tajima K, Takahashi F, Cui R, Gu T, Shimizu K, et al. Osteopontin modulates malignant pleural mesothelioma cell functions in vitro. Anticancer Res. 2009;29:2205-14 pubmed
Heuts J, Salber J, Goldyn A, Janser R, Möller M, Klee D. Bio-functionalized star PEG-coated PVDF surfaces for cytocompatibility-improved implant components. J Biomed Mater Res A. 2010;92:1538-51 pubmed publisher
Fievez V, Plapied L, des Rieux A, Pourcelle V, Freichels H, Wascotte V, et al. Targeting nanoparticles to M cells with non-peptidic ligands for oral vaccination. Eur J Pharm Biopharm. 2009;73:16-24 pubmed publisher
Wang H, Ma L, Yang S, Shao Z, Meng C, Duan D, et al. Effect of RGD-modified silk material on the adhesion and proliferation of bone marrow-derived mesenchymal stem cells. J Huazhong Univ Sci Technolog Med Sci. 2009;29:80-3 pubmed publisher
Perlin L, MacNeil S, Rimmer S. Cell adhesive hydrogels synthesised by copolymerisation of arg-protected Gly-Arg-Gly-Asp-Ser methacrylate monomers and enzymatic deprotection. Chem Commun (Camb). 2008;:5951-3 pubmed publisher
Norman M, Moriarty T, Dresser A, Millen B, Kubes P, Chaconas G. Molecular mechanisms involved in vascular interactions of the Lyme disease pathogen in a living host. PLoS Pathog. 2008;4:e1000169 pubmed publisher
Juhasz G, Vass G, Bozso Z, Budai D, Penke B, Szegedi V. Integrin activation modulates NMDA and AMPA receptor function of CA1 cells in a dose-related fashion in vivo. Brain Res. 2008;1233:20-6 pubmed publisher
Ali N, Gaughan A, Orosz C, Baran C, McMaken S, Wang Y, et al. Latency associated peptide has in vitro and in vivo immune effects independent of TGF-beta1. PLoS ONE. 2008;3:e1914 pubmed publisher
Pourcelle V, Devouge S, Garinot M, Préat V, Marchand Brynaert J. PCL-PEG-based nanoparticles grafted with GRGDS peptide: preparation and surface analysis by XPS. Biomacromolecules. 2007;8:3977-83 pubmed
Prime E, Hamid Z, Cooper White J, Qiao G. Addition of biological functionality to poly(epsilon-caprolactone) films. Biomacromolecules. 2007;8:2416-21 pubmed
Berg K, Zardeneta G, Hargreaves K, Clarke W, Milam S. Integrins regulate opioid receptor signaling in trigeminal ganglion neurons. Neuroscience. 2007;144:889-97 pubmed
Xiao Q, Zeng L, Zhang Z, Hu Y, Xu Q. Stem cell-derived Sca-1+ progenitors differentiate into smooth muscle cells, which is mediated by collagen IV-integrin alpha1/beta1/alphav and PDGF receptor pathways. Am J Physiol Cell Physiol. 2007;292:C342-52 pubmed
Iwamoto H, Sakai H, Tada S, Nakamuta M, Nawata H. Induction of apoptosis in rat hepatic stellate cells by disruption of integrin-mediated cell adhesion. J Lab Clin Med. 1999;134:83-9 pubmed
Dalmau S, Freitas C, Savino W. Upregulated expression of fibronectin receptors underlines the adhesive capability of thymocytes to thymic epithelial cells during the early stages of differentiation: lessons from sublethally irradiated mice. Blood. 1999;93:974-90 pubmed
Leon R, Hedlund T, Meech S, Li S, Schaack J, Hunger S, et al. Adenoviral-mediated gene transfer in lymphocytes. Proc Natl Acad Sci U S A. 1998;95:13159-64 pubmed
Faik A, Laboure A, Gulino D, Mandaron P, Falconet D. A plant surface protein sharing structural properties with animal integrins. Eur J Biochem. 1998;253:552-9 pubmed
Eberhard T, Virkola R, Korhonen T, Kronvall G, Ullberg M. Binding to human extracellular matrix by Neisseria meningitidis. Infect Immun. 1998;66:1791-4 pubmed
Oldberg A, Franzen A, Heinegard D. Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence. Proc Natl Acad Sci U S A. 1986;83:8819-23 pubmed
Saiki I, Murata J, Iida J, Sakurai T, Nishi N, Matsuno K, et al. Antimetastatic effects of synthetic polypeptides containing repeated structures of the cell adhesive Arg-Gly-Asp (RGD) and Tyr-Ile-Gly-Ser-Arg (YIGSR) sequences. Br J Cancer. 1989;60:722-8 pubmed
product information
Catalog Number :
G4391
Product Name :
Gly-Arg-Gly-Asp-Ser
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
≥97% (HPLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA