product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Anti-Guanylyl Cyclase α1 antibody produced in rabbit
catalog :
G4280
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunoprecipitation
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; human; loading ...; fig 9
  • western blot; human; 1:5000; loading ...; fig 9
Hochheiser J, Haase T, Busker M, Sömmer A, Kreienkamp H, Behrends S. Heterodimerization with the ?1 subunit directs the ?2 subunit of nitric oxide-sensitive guanylyl cyclase to calcium-insensitive cell-cell contacts in HEK293 cells: Interaction with Lin7a. Biochem Pharmacol. 2016;122:23-32 pubmed publisher
  • western blot; mouse; 1:1000; fig s5d
Erkens R, Kramer C, Lückstädt W, Panknin C, Krause L, Weidenbach M, et al. Left ventricular diastolic dysfunction in Nrf2 knock out mice is associated with cardiac hypertrophy, decreased expression of SERCA2a, and preserved endothelial function. Free Radic Biol Med. 2015;89:906-17 pubmed publisher
  • western blot; human
Herve D, Philippi A, Belbouab R, Zerah M, Chabrier S, Collardeau Frachon S, et al. Loss of ?1?1 soluble guanylate cyclase, the major nitric oxide receptor, leads to moyamoya and achalasia. Am J Hum Genet. 2014;94:385-94 pubmed publisher
Du L, Roberts J. Transforming growth factor-β downregulates sGC subunit expression in pulmonary artery smooth muscle cells via MEK and ERK signaling. Am J Physiol Lung Cell Mol Physiol. 2019;316:L20-L34 pubmed publisher
Thoonen R, Cauwels A, Decaluwé K, Geschka S, Tainsh R, Delanghe J, et al. Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice. Nat Commun. 2015;6:8482 pubmed publisher
André G, Sandoval J, Retailleau K, Loufrani L, Toumaniantz G, Offermanns S, et al. Smooth muscle specific Rac1 deficiency induces hypertension by preventing p116RIP3-dependent RhoA inhibition. J Am Heart Assoc. 2014;3:e000852 pubmed publisher
Kraehling J, Busker M, Haase T, Haase N, Koglin M, Linnenbaum M, et al. The amino-terminus of nitric oxide sensitive guanylyl cyclase ?? does not affect dimerization but influences subcellular localization. PLoS ONE. 2011;6:e25772 pubmed publisher
Cserép C, Szonyi A, Veres J, Németh B, Szabadits E, de Vente J, et al. Nitric oxide signaling modulates synaptic transmission during early postnatal development. Cereb Cortex. 2011;21:2065-74 pubmed publisher
Wilson G, Garthwaite J. Hyperpolarization-activated ion channels as targets for nitric oxide signalling in deep cerebellar nuclei. Eur J Neurosci. 2010;31:1935-45 pubmed publisher
product information
Catalog Number :
G4280
Product Name :
Anti-Guanylyl Cyclase α1 antibody produced in rabbit
Product Type :
ANTIBODIES - SIAL
Product Group :
Protein & Pathway Technologies
Host Species :
rabbit
Clonality :
polyclonal
Conjugation :
unconjugated
Product Description :
IgG fraction of antiserum, buffered aqueous solution
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA