| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; 1:1000; loading ...; fig 2c
| Polinski N, Martinez T, Gorodinsky A, Gareus R, Sasner M, Herberth M, et al. Decreased glucocerebrosidase activity and substrate accumulation of glycosphingolipids in a novel GBA1 D409V knock-in mouse model. PLoS ONE. 2021;16:e0252325 pubmed publisher |
- immunohistochemistry - free floating section; mouse; 1:1000; loading ...; fig 2e
| Massaro G, Mattar C, Wong A, Sirka E, Buckley S, Herbert B, et al. Fetal gene therapy for neurodegenerative disease of infants. Nat Med. 2018;24:1317-1323 pubmed publisher |
| Arrant A, Roth J, Boyle N, Kashyap S, Hoffmann M, Murchison C, et al. Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations. Acta Neuropathol Commun. 2019;7:218 pubmed publisher |
| Ysselstein D, Nguyen M, Young T, Severino A, Schwake M, Merchant K, et al. LRRK2 kinase activity regulates lysosomal glucocerebrosidase in neurons derived from Parkinson's disease patients. Nat Commun. 2019;10:5570 pubmed publisher |
| Li H, Ham A, Ma T, Kuo S, Kanter E, Kim D, et al. Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutations. Autophagy. 2019;15:113-130 pubmed publisher |
| Ivanova M, Changsila E, Turgut A, Goker Alpan O. Individualized screening for chaperone activity in Gaucher disease using multiple patient derived primary cell lines. Am J Transl Res. 2018;10:3750-3761 pubmed |
| Takeda S, Shimoda H, Takarada T, Imokawa G. Strawberry seed extract and its major component, tiliroside, promote ceramide synthesis in the stratum corneum of human epidermal equivalents. PLoS ONE. 2018;13:e0205061 pubmed publisher |
| Schultz M, Krus K, Kaushik S, Dang D, Chopra R, Qi L, et al. Coordinate regulation of mutant NPC1 degradation by selective ER autophagy and MARCH6-dependent ERAD. Nat Commun. 2018;9:3671 pubmed publisher |
| Cheng X, Xie Y, Zhou B, Huang N, Farfel Becker T, Sheng Z. Characterization of LAMP1-labeled nondegradative lysosomal and endocytic compartments in neurons. J Cell Biol. 2018;217:3127-3139 pubmed publisher |
| Kim M, Jeon S, Burbulla L, Krainc D. Acid ceramidase inhibition ameliorates α-synuclein accumulation upon loss of GBA1 function. Hum Mol Genet. 2018;27:1972-1988 pubmed publisher |
| Danyukova T, Ariunbat K, Thelen M, Brocke Ahmadinejad N, Mole S, Storch S. Loss of CLN7 results in depletion of soluble lysosomal proteins and impaired mTOR reactivation. Hum Mol Genet. 2018;27:1711-1722 pubmed publisher |
| Tayebi N, Parisiadou L, Berhe B, Gonzalez A, Serra Vinardell J, Tamargo R, et al. Glucocerebrosidase haploinsufficiency in A53T ?-synuclein mice impacts disease onset and course. Mol Genet Metab. 2017;122:198-208 pubmed publisher |
| Morabito G, Giannelli S, Ordazzo G, Bido S, Castoldi V, Indrigo M, et al. AAV-PHP.B-Mediated Global-Scale Expression in the Mouse Nervous System Enables GBA1 Gene Therapy for Wide Protection from Synucleinopathy. Mol Ther. 2017;25:2727-2742 pubmed publisher |
| Taguchi Y, Liu J, Ruan J, Pacheco J, Zhang X, Abbasi J, et al. Glucosylsphingosine Promotes α-Synuclein Pathology in Mutant GBA-Associated Parkinson's Disease. J Neurosci. 2017;37:9617-9631 pubmed publisher |
| Henderson M, Chung C, Riddle D, Zhang B, Gathagan R, Seeholzer S, et al. Unbiased Proteomics of Early Lewy Body Formation Model Implicates Active Microtubule Affinity-Regulating Kinases (MARKs) in Synucleinopathies. J Neurosci. 2017;37:5870-5884 pubmed publisher |
| Mazzulli J, Zunke F, Tsunemi T, Toker N, Jeon S, Burbulla L, et al. Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons. J Neurosci. 2016;36:7693-706 pubmed publisher |
| Choi S, Kim D, Kam T, Yun S, Kim S, Park H, et al. Lysosomal Enzyme Glucocerebrosidase Protects against Aβ1-42 Oligomer-Induced Neurotoxicity. PLoS ONE. 2015;10:e0143854 pubmed publisher |
| Marques A, Aten J, Ottenhoff R, van Roomen C, Herrera Moro D, Claessen N, et al. Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice. PLoS ONE. 2015;10:e0135889 pubmed publisher |
| Bae E, Yang N, Lee C, Lee H, Kim S, Sardi S, et al. Loss of glucocerebrosidase 1 activity causes lysosomal dysfunction and α-synuclein aggregation. Exp Mol Med. 2015;47:e153 pubmed publisher |
| Berger Z, Perkins S, Ambroise C, Oborski C, Calabrese M, Noell S, et al. Tool compounds robustly increase turnover of an artificial substrate by glucocerebrosidase in human brain lysates. PLoS ONE. 2015;10:e0119141 pubmed publisher |
