Xu X, Denic A, Jordan L, Wittenberg N, Warrington A, Wootla B, et al. A natural human IgM that binds to gangliosides is therapeutic in murine models of amyotrophic lateral sclerosis. Dis Model Mech. 2015;8:831-42 pubmed publisher

Przedpelski A, Tepp W, Kroken A, Fu Z, KIM J, Johnson E, et al. Enhancing the protective immune response against botulism. Infect Immun. 2013;81:2638-44 pubmed publisher

Willjes G, Mahrhold S, Strotmeier J, Eichner T, Rummel A, Binz T. Botulinum neurotoxin G binds synaptotagmin-II in a mode similar to that of serotype B: tyrosine 1186 and lysine 1191 cause its lower affinity. Biochemistry. 2013;52:3930-8 pubmed publisher

Whitemarsh R, Pier C, Tepp W, Pellett S, Johnson E. Model for studying Clostridium botulinum neurotoxin using differentiated motor neuron-like NG108-15 cells. Biochem Biophys Res Commun. 2012;427:426-30 pubmed publisher

Venkateshwari S, Veluraja K. Conformational analysis of GT1B ganglioside and its interaction with botulinum neurotoxin type B: a study by molecular modeling and molecular dynamics. J Biomol Struct Dyn. 2012;30:255-68 pubmed publisher

Sun S, Tepp W, Johnson E, Chapman E. Botulinum neurotoxins B and E translocate at different rates and exhibit divergent responses to GT1b and low pH. Biochemistry. 2012;51:5655-62 pubmed

Watanabe S, Higashi H, Ogawa H, Takamori K, Iwabuchi K. Involvement of ganglioside GT1b in glutamate release from neuroblastoma cells. Neurosci Lett. 2012;517:140-3 pubmed publisher

Singh M, Gupta G, Boopathi M, Gupta P, Chauhan V, Tomar A, et al. Deletion mutant comprising 198 residues of BoNT/A toxin receptor binding domain retained gt1b binding property but failed to induce protective antibody response in a mouse model. Protein Pept Lett. 2012;19:530-7 pubmed

Zhang Y, Zhang W, Johnston A, Newman T, Pyykko I, Zou J. Targeted delivery of Tet1 peptide functionalized polymersomes to the rat cochlear nerve. Int J Nanomedicine. 2012;7:1015-22 pubmed publisher

Viljetić B, Labak I, Majić S, Stambuk A, Heffer M. Distribution of mono-, di- and trisialo gangliosides in the brain of Actinopterygian fishes. Biochim Biophys Acta. 2012;1820:1437-43 pubmed publisher

Sun S, Suresh S, Liu H, Tepp W, Johnson E, Edwardson J, et al. Receptor binding enables botulinum neurotoxin B to sense low pH for translocation channel assembly. Cell Host Microbe. 2011;10:237-47 pubmed publisher

Chandrasekaran E, Xue J, Xia J, Locke R, Patil S, Neelamegham S, et al. Mammalian sialyltransferase ST3Gal-II: its exchange sialylation catalytic properties allow labeling of sialyl residues in mucin-type sialylated glycoproteins and specific gangliosides. Biochemistry. 2011;50:9475-87 pubmed publisher

Dong H, Jiang J, Chen Q. Development of a cell immobilization technique for the conversion of polysialogangliosides to monosialotetrahexosylganglioside. Pharm Biol. 2011;49:805-9 pubmed publisher

Watanabe S, Tan No K, Tadano T, Higashi H. Intraplantar injection of gangliosides produces nociceptive behavior and hyperalgesia via a glutamate signaling mechanism. Pain. 2011;152:327-34 pubmed publisher

Lim S, Esfahani K, Avdoshina V, Mocchetti I. Exogenous gangliosides increase the release of brain-derived neurotrophic factor. Neuropharmacology. 2011;60:1160-7 pubmed publisher

Yu R, Hou L, Yu C, Liu S, Ren J, Fang T, et al. Enhanced expression of soluble recombinant tetanus neurotoxin Hc in Escherichia coli as a tetanus vaccine candidate. Immunobiology. 2011;216:485-90 pubmed publisher

Gavella M, Kveder M, Lipovac V. Modulation of ROS production in human leukocytes by ganglioside micelles. Braz J Med Biol Res. 2010;43:942-9 pubmed

Kook K, Choi Y, Kim Y, Park S, Jou I, Kim S, et al. Altered ganglioside expression modulates the pathogenic mechanism of thyroid-associated ophthalmopathy by increase in hyaluronic acid. Invest Ophthalmol Vis Sci. 2011;52:264-73 pubmed publisher

Urbina P, Flores Díaz M, Alape Girón A, Alonso A, Goni F. Effects of bilayer composition and physical properties on the phospholipase C and sphingomyelinase activities of Clostridium perfringens α-toxin. Biochim Biophys Acta. 2011;1808:279-86 pubmed publisher

Qian M, Tsai B. Lipids and proteins act in opposing manners to regulate polyomavirus infection. J Virol. 2010;84:9840-52 pubmed publisher

Dong Y, Ikeda K, Hamamura K, Zhang Q, Kondo Y, Matsumoto Y, et al. GM1?/?GD1b?/?GA1 synthase expression results in the reduced cancer phenotypes with modulation of composition and raft-localization of gangliosides in a melanoma cell line. Cancer Sci. 2010;101:2039-47 pubmed publisher

Cao T, Zhang T, Wang L, Zhang L, Adachi T, Sato T, et al. Ganglioside GD1a suppression of NOS2 expression via ERK1 pathway in mouse osteosarcoma FBJ cells. J Cell Biochem. 2010;110:1165-74 pubmed publisher

Chung E, Bok E, Sohn S, Lee Y, Baik H, Jin B. GT1b-induced neurotoxicity is mediated by the Akt/GSK-3/tau signaling pathway but not caspase-3 in mesencephalic dopaminergic neurons. BMC Neurosci. 2010;11:74 pubmed publisher

Ebrahimi F, Rasaee M, Mousavi S, Babaeipour V. Production and characterization of a recombinant chimeric antigen consisting botulinum neurotoxin serotypes A, B and E binding subdomains. J Toxicol Sci. 2010;35:9-19 pubmed

Behrensdorf Nicol H, Bonifas U, Kegel B, Silberbach K, Kramer B, Weisser K. In vitro determination of tetanus toxicity by an endopeptidase assay linked to a ganglioside-binding step. Toxicol In Vitro. 2010;24:988-94 pubmed publisher

Serb A, Schiopu C, Flangea C, Sisu E, Zamfir A. Top-down glycolipidomics: fragmentation analysis of ganglioside oligosaccharide core and ceramide moiety by chip-nanoelectrospray collision-induced dissociation MS2-MS6. J Mass Spectrom. 2009;44:1434-42 pubmed publisher

Hamasaki H, Aoyagi M, Kasama T, Handa S, Hirakawa K, Taki T. GT1b in human metastatic brain tumors: GT1b as a brain metastasis-associated ganglioside. Biochim Biophys Acta. 1999;1437:93-9 pubmed

Favaron M, Manev H, Alho H, Bertolino M, Ferret B, Guidotti A, et al. Gangliosides prevent glutamate and kainate neurotoxicity in primary neuronal cultures of neonatal rat cerebellum and cortex. Proc Natl Acad Sci U S A. 1988;85:7351-5 pubmed