This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
β-Galactosidase from Escherichia coli
catalog :
G3153
citations: 98
Reference
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Seras Franzoso J, Affentranger R, Ferrer Navarro M, Daura X, Villaverde A, García Fruitós E. Disulfide bond formation and activation of Escherichia coli ?-galactosidase under oxidizing conditions. Appl Environ Microbiol. 2012;78:2376-85 pubmed publisher
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Hofer D, Paul K, Fantur K, Beck M, Bürger F, Caillaud C, et al. GM1 gangliosidosis and Morquio B disease: expression analysis of missense mutations affecting the catalytic site of acid beta-galactosidase. Hum Mutat. 2009;30:1214-21 pubmed publisher
Chen R, Jiang X, Sun D, Han G, Wang F, Ye M, et al. Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. J Proteome Res. 2009;8:651-61 pubmed publisher
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Gort L, Santamaria R, Grinberg D, Vilageliu L, Chabas A. Identification of a novel pseudodeficiency allele in the GLB1 gene in a carrier of GM1 gangliosidosis. Clin Genet. 2007;72:109-11 pubmed
Santamaria R, Blanco M, Chabas A, Grinberg D, Vilageliu L. Identification of 14 novel GLB1 mutations, including five deletions, in 19 patients with GM1 gangliosidosis from South America. Clin Genet. 2007;71:273-9 pubmed
Santamaria R, Chabas A, Coll M, Miranda C, Vilageliu L, Grinberg D. Twenty-one novel mutations in the GLB1 gene identified in a large group of GM1-gangliosidosis and Morquio B patients: possible common origin for the prevalent p.R59H mutation among gypsies. Hum Mutat. 2006;27:1060 pubmed
Bauer W, Talmadge K, Keegstra K, Albersheim P. The Structure of Plant Cell Walls: II. The Hemicellulose of the Walls of Suspension-cultured Sycamore Cells. Plant Physiol. 1973;51:174-87 pubmed
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Tatano Y, Takeuchi N, Kuwahara J, Sakuraba H, Takahashi T, Takada G, et al. Elastogenesis in cultured dermal fibroblasts from patients with lysosomal beta-galactosidase, protective protein/cathepsin A and neuraminidase-1 deficiencies. J Med Invest. 2006;53:103-12 pubmed
Lewandrowski U, Moebius J, Walter U, Sickmann A. Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach. Mol Cell Proteomics. 2006;5:226-33 pubmed
Roze E, Paschke E, Lopez N, Eck T, Yoshida K, Maurel Ollivier A, et al. Dystonia and parkinsonism in GM1 type 3 gangliosidosis. Mov Disord. 2005;20:1366-9 pubmed
Gururaj A, Sztriha L, Hertecant J, Johansen J, Georgiou T, Campos Y, et al. Magnetic resonance imaging findings and novel mutations in GM1 gangliosidosis. J Child Neurol. 2005;20:57-60 pubmed
Caciotti A, Donati M, Boneh A, D AZZO A, Federico A, Parini R, et al. Role of beta-galactosidase and elastin binding protein in lysosomal and nonlysosomal complexes of patients with GM1-gangliosidosis. Hum Mutat. 2005;25:285-92 pubmed
Gerhard D, Wagner L, Feingold E, Shenmen C, Grouse L, Schuler G, et al. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004;14:2121-7 pubmed
Georgiou T, Drousiotou A, Campos Y, Caciotti A, Sztriha L, Gururaj A, et al. Four novel mutations in patients from the Middle East with the infantile form of GM1-gangliosidosis. Hum Mutat. 2004;24:352 pubmed
Monod J, Cohn M. [Biosynthesis induced by enzymes; enzymatic adaptation]. Adv Enzymol Relat Subj Biochem. 1952;13:67-119 pubmed
Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, et al. Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat Genet. 2004;36:40-5 pubmed
Landman O. Properties and induction of beta-galactosidase in Bacillus megaterium. Biochim Biophys Acta. 1957;23:558-69 pubmed
Caciotti A, Bardelli T, Cunningham J, D AZZO A, Zammarchi E, Morrone A. Modulating action of the new polymorphism L436F detected in the GLB1 gene of a type-II GM1 gangliosidosis patient. Hum Genet. 2003;113:44-50 pubmed
Bagshaw R, Zhang S, Hinek A, Skomorowski M, Whelan D, Clarke J, et al. Novel mutations (Asn 484 Lys, Thr 500 Ala, Gly 438 Glu) in Morquio B disease. Biochim Biophys Acta. 2002;1588:247-53 pubmed
Paschke E, Milos I, Kreimer Erlacher H, Hoefler G, Beck M, Hoeltzenbein M, et al. Mutation analyses in 17 patients with deficiency in acid beta-galactosidase: three novel point mutations and high correlation of mutation W273L with Morquio disease type B. Hum Genet. 2001;109:159-66 pubmed
Hinek A, Zhang S, Smith A, Callahan J. Impaired elastic-fiber assembly by fibroblasts from patients with either Morquio B disease or infantile GM1-gangliosidosis is linked to deficiency in the 67-kD spliced variant of beta-galactosidase. Am J Hum Genet. 2000;67:23-36 pubmed
Zhang S, Bagshaw R, Hilson W, Oho Y, Hinek A, Clarke J, et al. Characterization of beta-galactosidase mutations Asp332-->Asn and Arg148-->Ser, and a polymorphism, Ser532-->Gly, in a case of GM1 gangliosidosis. Biochem J. 2000;348 Pt 3:621-32 pubmed
Morrone A, Bardelli T, Donati M, Giorgi M, Di Rocco M, Gatti R, et al. beta-galactosidase gene mutations affecting the lysosomal enzyme and the elastin-binding protein in GM1-gangliosidosis patients with cardiac involvement. Hum Mutat. 2000;15:354-66 pubmed
Callahan J. Molecular basis of GM1 gangliosidosis and Morquio disease, type B. Structure-function studies of lysosomal beta-galactosidase and the non-lysosomal beta-galactosidase-like protein. Biochim Biophys Acta. 1999;1455:85-103 pubmed
Silva C, Severini M, Sopelsa A, Coelho J, Zaha A, d Azzo A, et al. Six novel beta-galactosidase gene mutations in Brazilian patients with GM1-gangliosidosis. Hum Mutat. 1999;13:401-9 pubmed
Juers D, Huber R, Matthews B. Structural comparisons of TIM barrel proteins suggest functional and evolutionary relationships between beta-galactosidase and other glycohydrolases. Protein Sci. 1999;8:122-36 pubmed
Privitera S, Prody C, Callahan J, Hinek A. The 67-kDa enzymatically inactive alternatively spliced variant of beta-galactosidase is identical to the elastin/laminin-binding protein. J Biol Chem. 1998;273:6319-26 pubmed
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Kaye E, Shalish C, Livermore J, Taylor H, Stevenson R, Breakefield X. beta-Galactosidase gene mutations in patients with slowly progressive GM1 gangliosidosis. J Child Neurol. 1997;12:242-7 pubmed
Hinek A. Biological roles of the non-integrin elastin/laminin receptor. Biol Chem. 1996;377:471-80 pubmed
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Boustany R, Qian W, Suzuki K. Mutations in acid beta-galactosidase cause GM1-gangliosidosis in American patients. Am J Hum Genet. 1993;53:881-8 pubmed
Chakraborty S, Rafi M, Wenger D. Mutations in the lysosomal beta-galactosidase gene that cause the adult form of GM1 gangliosidosis. Am J Hum Genet. 1994;54:1004-13 pubmed
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Asp N, Dahlqvist A, Koldovsky O. Human small-intestinal beta-galactosidases. Separation and characterization of one lactase and one hetero beta-galactosidase. Biochem J. 1969;114:351-9 pubmed
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Oshima A, Tsuji A, Nagao Y, Sakuraba H, Suzuki Y. Cloning, sequencing, and expression of cDNA for human beta-galactosidase. Biochem Biophys Res Commun. 1988;157:238-44 pubmed
Morreau H, Galjart N, Gillemans N, Willemsen R, van der Horst G, d Azzo A. Alternative splicing of beta-galactosidase mRNA generates the classic lysosomal enzyme and a beta-galactosidase-related protein. J Biol Chem. 1989;264:20655-63 pubmed
Yamamoto Y, Hake C, Martin B, Kretz K, Ahern Rindell A, Naylor S, et al. Isolation, characterization, and mapping of a human acid beta-galactosidase cDNA. DNA Cell Biol. 1990;9:119-27 pubmed
Oshima A, Yoshida K, Shimmoto M, Fukuhara Y, Sakuraba H, Suzuki Y. Human beta-galactosidase gene mutations in morquio B disease. Am J Hum Genet. 1991;49:1091-3 pubmed
Nishimoto J, Nanba E, Inui K, Okada S, Suzuki K. GM1-gangliosidosis (genetic beta-galactosidase deficiency): identification of four mutations in different clinical phenotypes among Japanese patients. Am J Hum Genet. 1991;49:566-74 pubmed
Yoshida K, Oshima A, Shimmoto M, Fukuhara Y, Sakuraba H, Yanagisawa N, et al. Human beta-galactosidase gene mutations in GM1-gangliosidosis: a common mutation among Japanese adult/chronic cases. Am J Hum Genet. 1991;49:435-42 pubmed
Mosna G, Fattore S, Tubiello G, Brocca S, Trubia M, Gianazza E, et al. A homozygous missense arginine to histidine substitution at position 482 of the beta-galactosidase in an Italian infantile GM1-gangliosidosis patient. Hum Genet. 1992;90:247-50 pubmed
product information
Catalog Number :
G3153
Product Name :
β-Galactosidase from Escherichia coli
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
lyophilized powder, ?500 units/mg protein
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA