This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
L-Glutamic Dehydrogenase from bovine liver
catalog :
G2626
citations: 41
Reference
Ruegenberg S, Horn M, Pichlo C, Allmeroth K, Baumann U, Denzel M. Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis. Nat Commun. 2020;11:687 pubmed publisher
Kasatkina L, Heinemann A, Hudz Y, Thomas D, Sturm E. Stearoylethanolamide interferes with retrograde endocannabinoid signalling and supports the blood-brain barrier integrity under acute systemic inflammation. Biochem Pharmacol. 2020;174:113783 pubmed publisher
Kasatkina L, Tarasenko A, Krupko O, Kuchmerovska T, Lisakovska O, Trikash I. Vitamin D deficiency induces the excitation/inhibition brain imbalance and the proinflammatory shift. Int J Biochem Cell Biol. 2020;119:105665 pubmed publisher
Cheng F, Yang J, Schwaneberg U, Zhu L. Rational surface engineering of an arginine deiminase (an antitumor enzyme) for increased PEGylation efficiency. Biotechnol Bioeng. 2019;116:2156-2166 pubmed publisher
Roginski A, Cecatto C, Wajner S, Camera F, Castilho R, Wajner M, et al. Experimental evidence that maleic acid markedly compromises glutamate oxidation through inhibition of glutamate dehydrogenase and α-ketoglutarate dehydrogenase activities in kidney of developing rats. Mol Cell Biochem. 2019;: pubmed publisher
Wang X, Tamiev D, Alagurajan J, DiSpirito A, Phillips G, Hargrove M. The role of the NADH-dependent nitrite reductase, Nir, from Escherichia coli in fermentative ammonification. Arch Microbiol. 2019;201:519-530 pubmed publisher
Fets L, Driscoll P, Grimm F, Jain A, Nunes P, Gounis M, et al. MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG. Nat Chem Biol. 2018;14:1032-1042 pubmed publisher
Dechorgnat J, Francis K, Dhugga K, Rafalski J, Tyerman S, Kaiser B. Root Ideotype Influences Nitrogen Transport and Assimilation in Maize. Front Plant Sci. 2018;9:531 pubmed publisher
Divakaruni A, Andreyev A, Rogers G, Murphy A. In situ measurements of mitochondrial matrix enzyme activities using plasma and mitochondrial membrane permeabilization agents. Anal Biochem. 2018;552:60-65 pubmed publisher
Grimaldi M, Karaca M, Latini L, Brioudes E, Schalch T, Maechler P. Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia. Hum Mol Genet. 2017;26:3453-3465 pubmed publisher
Maneshi M, Maki B, Gnanasambandam R, Belin S, Popescu G, Sachs F, et al. Mechanical stress activates NMDA receptors in the absence of agonists. Sci Rep. 2017;7:39610 pubmed publisher
Coze F, Gilard F, Tcherkez G, Virolle M, Guyonvarch A. Carbon-flux distribution within Streptomyces coelicolor metabolism: a comparison between the actinorhodin-producing strain M145 and its non-producing derivative M1146. PLoS ONE. 2013;8:e84151 pubmed publisher
Roberts M, Crail J, Laffoon M, Fernandez W, Menze M, Konkle M. Identification of disulfide bond formation between MitoNEET and glutamate dehydrogenase 1. Biochemistry. 2013;52:8969-71 pubmed publisher
Son J, Lyssiotis C, Ying H, Wang X, Hua S, Ligorio M, et al. Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway. Nature. 2013;496:101-5 pubmed publisher
Faletra F, Athanasakis E, Morgan A, Biarnés X, Fornasier F, Parini R, et al. Congenital hyperinsulinism: clinical and molecular analysis of a large Italian cohort. Gene. 2013;521:160-5 pubmed publisher
Snider K, Becker S, Boyajian L, Shyng S, MacMullen C, Hughes N, et al. Genotype and phenotype correlations in 417 children with congenital hyperinsulinism. J Clin Endocrinol Metab. 2013;98:E355-63 pubmed publisher
Miyamoto R, Goto S, Sako W, Miyashiro A, Kim I, Escande F, et al. Generalized dystonia in a patient with a novel mutation in the GLUD1 gene. Mov Disord. 2012;27:1198-9 pubmed publisher
Zaganas I, Spanaki C, Plaitakis A. Expression of human GLUD2 glutamate dehydrogenase in human tissues: functional implications. Neurochem Int. 2012;61:455-62 pubmed publisher
Kotzamani D, Plaitakis A. Alpha helical structures in the leader sequence of human GLUD2 glutamate dehydrogenase responsible for mitochondrial import. Neurochem Int. 2012;61:463-9 pubmed publisher
Spanaki C, Zaganas I, Kounoupa Z, Plaitakis A. The complex regulation of human glud1 and glud2 glutamate dehydrogenases and its implications in nerve tissue biology. Neurochem Int. 2012;61:470-81 pubmed publisher
Munawar N, Engel P. Overexpression in a non-native halophilic host and biotechnological potential of NAD+-dependent glutamate dehydrogenase from Halobacterium salinarum strain NRC-36014. Extremophiles. 2012;16:463-76 pubmed publisher
Aso K, Okano Y, Takeda T, Sakamoto O, Ban K, Iida K, et al. Spectrum of glutamate dehydrogenase mutations in Japanese patients with congenital hyperinsulinism and hyperammonemia syndrome. Osaka City Med J. 2011;57:1-9 pubmed
Spanaki C, Plaitakis A. The role of glutamate dehydrogenase in mammalian ammonia metabolism. Neurotox Res. 2012;21:117-27 pubmed publisher
Balasubramaniam S, Kapoor R, Yeow J, Lim P, Flanagan S, Ellard S, et al. Biochemical evaluation of an infant with hypoglycemia resulting from a novel de novo mutation of the GLUD1 gene and hyperinsulinism-hyperammonemia syndrome. J Pediatr Endocrinol Metab. 2011;24:573-7 pubmed
Bailey J, Powell L, Sinanan L, Neal J, Li M, Smith T, et al. A novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysis. FEBS J. 2011;278:3140-51 pubmed publisher
Hutson S, Islam M, Zaganas I. Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways. Neurochem Int. 2011;59:518-24 pubmed publisher
Plaitakis A, Latsoudis H, Spanaki C. The human GLUD2 glutamate dehydrogenase and its regulation in health and disease. Neurochem Int. 2011;59:495-509 pubmed publisher
Perez Errazquin F, Sempere Fernández J, Garcia Martin G, Chamorro Munoz M, Romero Acebal M. Hyperinsulinism and hyperammonaemia syndrome and severe myoclonic epilepsy of infancy. Neurologia. 2011;26:248-52 pubmed publisher
Stanley C. Two genetic forms of hyperinsulinemic hypoglycemia caused by dysregulation of glutamate dehydrogenase. Neurochem Int. 2011;59:465-72 pubmed publisher
Junk A, Goel M, Mundorf T, Rockwood E, Bhattacharya S. Decreased carbohydrate metabolism enzyme activities in the glaucomatous trabecular meshwork. Mol Vis. 2010;16:1286-91 pubmed
Yuzaki M. Synapse formation and maintenance by C1q family proteins: a new class of secreted synapse organizers. Eur J Neurosci. 2010;32:191-7 pubmed publisher
Spanaki C, Zaganas I, Kleopa K, Plaitakis A. Human GLUD2 glutamate dehydrogenase is expressed in neural and testicular supporting cells. J Biol Chem. 2010;285:16748-56 pubmed publisher
Plaitakis A, Latsoudis H, Kanavouras K, Ritz B, Bronstein J, Skoula I, et al. Gain-of-function variant in GLUD2 glutamate dehydrogenase modifies Parkinson's disease onset. Eur J Hum Genet. 2010;18:336-41 pubmed publisher
Toivari M, Maaheimo H, Penttila M, Ruohonen L. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol. Appl Microbiol Biotechnol. 2010;85:731-9 pubmed publisher
Karimi M, Bereczky Z, Cohan N, Muszbek L. Factor XIII Deficiency. Semin Thromb Hemost. 2009;35:426-38 pubmed publisher
Zaganas I, Kanavouras K, Mastorodemos V, Latsoudis H, Spanaki C, Plaitakis A. The human GLUD2 glutamate dehydrogenase: localization and functional aspects. Neurochem Int. 2009;55:52-63 pubmed publisher
Kanavouras K, Borompokas N, Latsoudis H, Stagourakis A, Zaganas I, Plaitakis A. Mutations in human GLUD2 glutamate dehydrogenase affecting basal activity and regulation. J Neurochem. 2009;109 Suppl 1:167-73 pubmed publisher
Kosenko E, Venediktova N, Kudryavtsev A, Ataullakhanov F, Kaminsky Y, Felipo V, et al. Encapsulation of glutamine synthetase in mouse erythrocytes: a new procedure for ammonia detoxification. Biochem Cell Biol. 2008;86:469-76 pubmed publisher
Rosso L, Marques A, Reichert A, Kaessmann H. Mitochondrial targeting adaptation of the hominoid-specific glutamate dehydrogenase driven by positive Darwinian selection. PLoS Genet. 2008;4:e1000150 pubmed publisher
Strecker H. Glutamic dehydrogenase. Arch Biochem Biophys. 1953;46:128-40 pubmed
Olson J, Anfinsen C. The crystallization and characterization of L-glutamic acid dehydrogenase. J Biol Chem. 1952;197:67-79 pubmed
product information
Catalog Number :
G2626
Product Name :
L-Glutamic Dehydrogenase from bovine liver
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
Type II, ammonium sulfate suspension, ?35 units/mg protein
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA