This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Glucagon
catalog :
G1774
citations: 78
Reference
Fang P, Sun Y, Gu X, Shi M, Bo P, Zhang Z, et al. Baicalin ameliorates hepatic insulin resistance and gluconeogenic activity through inhibition of p38 MAPK/PGC-1α pathway. Phytomedicine. 2019;64:153074 pubmed publisher
Nishimura W, Kapoor A, El Khattabi I, Jin W, Yasuda K, Bonner Weir S, et al. Compensatory Response by Late Embryonic Tubular Epithelium to the Reduction in Pancreatic Progenitors. PLoS ONE. 2015;10:e0142286 pubmed publisher
Bjerre Harpøth V, Storm A, Eslamizad M, Kuhla B, Larsen M. Effect of propylene glycol on adipose tissue mobilization in postpartum over-conditioned Holstein cows. J Dairy Sci. 2015;98:8581-96 pubmed publisher
Hugill A, Stewart M, Yon M, Probert F, Cox I, Hough T, et al. Loss of arylformamidase with reduced thymidine kinase expression leads to impaired glucose tolerance. Biol Open. 2015;4:1367-75 pubmed publisher
Hou S, Li C, Huan Y, Liu S, Liu Q, Sun S, et al. Effects of E2HSA, a Long-Acting Glucagon Like Peptide-1 Receptor Agonist, on Glycemic Control and Beta Cell Function in Spontaneous Diabetic db/db Mice. J Diabetes Res. 2015;2015:817839 pubmed publisher
Wang H, Wang X, Zhu Y, Chen F, Sun Y, Han X. Increased androgen levels in rats impair glucose-stimulated insulin secretion through disruption of pancreatic beta cell mitochondrial function. J Steroid Biochem Mol Biol. 2015;154:254-66 pubmed publisher
Ghaye A, Bergemann D, Tarifeño Saldivia E, Flasse L, Von Berg V, Peers B, et al. Progenitor potential of nkx6.1-expressing cells throughout zebrafish life and during beta cell regeneration. BMC Biol. 2015;13:70 pubmed publisher
Mastracci T, Robertson M, Mirmira R, Anderson R. Polyamine biosynthesis is critical for growth and differentiation of the pancreas. Sci Rep. 2015;5:13269 pubmed publisher
Gomez D, O Driscoll M, Sheets T, Hruban R, Oberholzer J, McGarrigle J, et al. Neurogenin 3 Expressing Cells in the Human Exocrine Pancreas Have the Capacity for Endocrine Cell Fate. PLoS ONE. 2015;10:e0133862 pubmed publisher
Yi J, Warunek D, Craft D. Degradation and Stabilization of Peptide Hormones in Human Blood Specimens. PLoS ONE. 2015;10:e0134427 pubmed publisher
Merino B, Quesada I, Hernández Cascales J. Glucagon Increases Beating Rate but Not Contractility in Rat Right Atrium. Comparison with Isoproterenol. PLoS ONE. 2015;10:e0132884 pubmed publisher
Shah F, Leung L, Barton H, Will Y, Rodrigues A, Greene N, et al. Setting Clinical Exposure Levels of Concern for Drug-Induced Liver Injury (DILI) Using Mechanistic in vitro Assays. Toxicol Sci. 2015;147:500-14 pubmed publisher
Takano Y, Kasai K, Takagishi Y, Kikumori T, Imai T, Murata Y, et al. Pancreatic Neuroendocrine Tumors in Mice Deficient in Proglucagon-Derived Peptides. PLoS ONE. 2015;10:e0133812 pubmed publisher
Martin D, Kim Y, Sever D, Mao C, Haefliger J, Grapin Botton A. REST represses a subset of the pancreatic endocrine differentiation program. Dev Biol. 2015;405:316-27 pubmed publisher
Han Y, Ryu S, Park S, Lee K, Lee S, Ho W. Ca(2+) clearance by plasmalemmal NCLX, Li(+)-permeable Na(+)/Ca(2+) exchanger, is required for the sustained exocytosis in rat insulinoma INS-1 cells. Pflugers Arch. 2015;467:2461-72 pubmed publisher
Sasaki T, Kuroko M, Sekine S, Matsui S, Kikuchi O, Susanti V, et al. Overexpression of insulin receptor partially improves obese and diabetic phenotypes in db/db mice. Endocr J. 2015;62:787-96 pubmed publisher
Singh S, Chen Y, Matsumoto A, Orlicky D, Dong H, Thompson D, et al. ALDH1B1 links alcohol consumption and diabetes. Biochem Biophys Res Commun. 2015;463:768-773 pubmed publisher
Hirabaru M, Kuroki T, Adachi T, Kitasato A, Ono S, Tanaka T, et al. A Method for Performing Islet Transplantation Using Tissue-Engineered Sheets of Islets and Mesenchymal Stem Cells. Tissue Eng Part C Methods. 2015;21:1205-15 pubmed publisher
Shields E, Lam C, Cox A, Rankin M, Van Winkle T, Hess R, et al. Extreme Beta-Cell Deficiency in Pancreata of Dogs with Canine Diabetes. PLoS ONE. 2015;10:e0129809 pubmed publisher
Taniguchi K, Russell M, Richardson S, Morgan N. The subcellular distribution of cyclin-D1 and cyclin-D3 within human islet cells varies according to the status of the pancreas donor. Diabetologia. 2015;58:2056-63 pubmed publisher
Okamoto H, Kim J, Aglione J, Lee J, Cavino K, Na E, et al. Glucagon Receptor Blockade With a Human Antibody Normalizes Blood Glucose in Diabetic Mice and Monkeys. Endocrinology. 2015;156:2781-94 pubmed publisher
Huang C, Yuan L, Cao S. Endogenous GLP-1 as a key self-defense molecule against lipotoxicity in pancreatic islets. Int J Mol Med. 2015;36:173-85 pubmed publisher
Bloch K, Gil Ad I, Tarasenko I, Vanichkin A, Taler M, Hornfeld S, et al. Intracranial pancreatic islet transplantation increases islet hormone expression in the rat brain and attenuates behavioral dysfunctions induced by MK-801 (dizocilpine). Horm Behav. 2015;72:1-11 pubmed publisher
Tamura K, Minami K, Kudo M, Iemoto K, Takahashi H, Seino S. Liraglutide improves pancreatic Beta cell mass and function in alloxan-induced diabetic mice. PLoS ONE. 2015;10:e0126003 pubmed publisher
Ludvigsen E, Carlsson C, Tiensuu Janson E, Sandler S, Stridsberg M. Somatostatin receptor 1-5; expression profiles during rat development. Ups J Med Sci. 2015;120:157-68 pubmed publisher
Bonfanti P, Nobecourt E, Oshima M, Albagli Curiel O, Laurysens V, Stangé G, et al. Ex Vivo Expansion and Differentiation of Human and Mouse Fetal Pancreatic Progenitors Are Modulated by Epidermal Growth Factor. Stem Cells Dev. 2015;24:1766-78 pubmed publisher
Bueno P, Yochite J, Derigge Pisani G, Malmegrim de Farias K, de Avó L, Voltarelli J, et al. Metabolic and pancreatic effects of bone marrow mesenchymal stem cells transplantation in mice fed high-fat diet. PLoS ONE. 2015;10:e0124369 pubmed publisher
Oskarsson M, Singh K, Wang J, Vlodavsky I, Li J, Westermark G. Heparan Sulfate Proteoglycans Are Important for Islet Amyloid Formation and Islet Amyloid Polypeptide-induced Apoptosis. J Biol Chem. 2015;290:15121-32 pubmed publisher
Abdellatif A, Ogata K, Kudo T, Xiafukaiti G, Chang Y, Katoh M, et al. Role of large MAF transcription factors in the mouse endocrine pancreas. Exp Anim. 2015;64:305-12 pubmed publisher
Ramesh N, Mohan H, Unniappan S. Nucleobindin-1 encodes a nesfatin-1-like peptide that stimulates insulin secretion. Gen Comp Endocrinol. 2015;216:182-9 pubmed publisher
Streckel E, Braun Reichhart C, Herbach N, Dahlhoff M, Kessler B, Blutke A, et al. Effects of the glucagon-like peptide-1 receptor agonist liraglutide in juvenile transgenic pigs modeling a pre-diabetic condition. J Transl Med. 2015;13:73 pubmed publisher
Oh B, Jin S, Choi J, Oh S, Shim W, Lee M, et al. Improved revascularization of islet grafts using an angiogenic monocyte subpopulation derived from spheroid culture of bone marrow mononuclear cells. Am J Transplant. 2015;15:1543-54 pubmed publisher
Woolcott O, Richey J, Kabir M, Chow R, Iyer M, Kirkman E, et al. High-fat diet-induced insulin resistance does not increase plasma anandamide levels or potentiate anandamide insulinotropic effect in isolated canine islets. PLoS ONE. 2015;10:e0123558 pubmed publisher
Basso A, Pelegrini P, Mulinari F, Costa M, Viana A, Silva L, et al. Recombinant glucagon: a differential biological activity. AMB Express. 2015;5:20 pubmed publisher
Brown M, Ungerleider N, Bonomi L, Andrzejewski D, Burnside A, Schneyer A. Effects of activin A on survival, function and gene expression of pancreatic islets from non-diabetic and diabetic human donors. Islets. 2014;6:e1017226 pubmed publisher
Oliveira R, Maschio D, Carvalho C, Collares Buzato C. Influence of gender and time diet exposure on endocrine pancreas remodeling in response to high fat diet-induced metabolic disturbances in mice. Ann Anat. 2015;200:88-97 pubmed publisher
Nagaraj V, King B, Storm P, Vikman P, Ottosson Laakso E, Blom A, et al. Complement inhibitor CD55 governs the integrity of membrane rafts in pancreatic beta cells, but plays no role in insulin secretion. Biochem Biophys Res Commun. 2015;460:518-24 pubmed publisher
Dalgin G, Prince V. Differential levels of Neurod establish zebrafish endocrine pancreas cell fates. Dev Biol. 2015;402:81-97 pubmed publisher
Behnam Azad B, Rota V, Yu L, McGirr R, St Amant A, Lee T, et al. Synthesis and evaluation of optical and PET GLP-1 peptide analogues for GLP-1R imaging. Mol Imaging. 2015;14: pubmed publisher
Chen J, Chen S, Huang P, Meng X, Clayton S, Shen J, et al. In vivo targeted delivery of ANGPTL8 gene for beta cell regeneration in rats. Diabetologia. 2015;58:1036-44 pubmed publisher
Sharivkin R, Walker M, Soen Y. Functional proteomics screen enables enrichment of distinct cell types from human pancreatic islets. PLoS ONE. 2015;10:e0115100 pubmed publisher
Reddy S, Zeng N, Al Diery H, Jung D, Yeu C, Joret M, et al. Analysis of peri-islet CD45-positive leucocytic infiltrates in long-standing type 1 diabetic patients. Diabetologia. 2015;58:1024-35 pubmed publisher
Brackeva B, De Punt V, Kramer G, Costa O, Verhaeghen K, Stange G, et al. Potential of UCHL1 as biomarker for destruction of pancreatic beta cells. J Proteomics. 2015;117:156-67 pubmed publisher
Chen L, So W, Li S, Cheng Q, Boucher B, Leung P. Niacin-induced hyperglycemia is partially mediated via niacin receptor GPR109a in pancreatic islets. Mol Cell Endocrinol. 2015;404:56-66 pubmed publisher
Farmer T, Jenkins E, O Brien T, McCoy G, Havlik A, Nass E, et al. Comparison of the physiological relevance of systemic vs. portal insulin delivery to evaluate whole body glucose flux during an insulin clamp. Am J Physiol Endocrinol Metab. 2015;308:E206-22 pubmed publisher
Thorens B, Tarussio D, Maestro M, Rovira M, Heikkilä E, Ferrer J. Ins1(Cre) knock-in mice for beta cell-specific gene recombination. Diabetologia. 2015;58:558-65 pubmed publisher
Ren L, Chen L, Qi H, Li F, Gong F. In vitro differentiation of human adipose tissue-derived stem cells into islet-like clusters promoted by islet neogenesis-associated protein pentadecapeptide. Cells Tissues Organs. 2014;199:329-41 pubmed publisher
Brandt C, Hansen R, Hansen J, Olsen C, Galle P, Mandrup Poulsen T, et al. Over-expression of Follistatin-like 3 attenuates fat accumulation and improves insulin sensitivity in mice. Metabolism. 2015;64:283-95 pubmed publisher
Lelliott C, Ahnmark A, Admyre T, Ahlstedt I, Irving L, Keyes F, et al. Monoclonal antibody targeting of fibroblast growth factor receptor 1c ameliorates obesity and glucose intolerance via central mechanisms. PLoS ONE. 2014;9:e112109 pubmed publisher
Ding L, Han L, Li Y, Zhao J, He P, Zhang W. Neurogenin 3-directed cre deletion of Tsc1 gene causes pancreatic acinar carcinoma. Neoplasia. 2014;16:909-17 pubmed publisher
Busek P, Hrabal P, Fric P, Sedo A. Co-expression of the homologous proteases fibroblast activation protein and dipeptidyl peptidase-IV in the adult human Langerhans islets. Histochem Cell Biol. 2015;143:497-504 pubmed publisher
Tachibana K, Sakurai K, Yokoh H, Ishibashi T, Ishikawa K, Shirasawa T, et al. Mutation in insulin receptor attenuates oxidative stress and apoptosis in pancreatic beta-cells induced by nutrition excess: reduced insulin signaling and ROS. Horm Metab Res. 2015;47:176-83 pubmed publisher
Liu L, Omar B, Marchetti P, Ahren B. Dipeptidyl peptidase-4 (DPP-4): Localization and activity in human and rodent islets. Biochem Biophys Res Commun. 2014;453:398-404 pubmed publisher
Ioachimescu A, Hampstead B, Moore A, Burgess E, Phillips L. Growth hormone deficiency after mild combat-related traumatic brain injury. Pituitary. 2015;18:535-41 pubmed publisher
Kahraman S, Dirice E, De Jesus D, Hu J, Kulkarni R. Maternal insulin resistance and transient hyperglycemia impact the metabolic and endocrine phenotypes of offspring. Am J Physiol Endocrinol Metab. 2014;307:E906-18 pubmed publisher
Kasacka I, Janiuk I, Piotrowska Z. Evaluation of CART-, glucagon-, and insulin-immunoreactive cells in the pancreas of an experimental rat model of unilateral renal artery stenosis. Histol Histopathol. 2015;30:445-52 pubmed publisher
Theodoraki A, Hu Y, Poopalasundaram S, Oosterhof A, Guimond S, Disterer P, et al. Distinct patterns of heparan sulphate in pancreatic islets suggest novel roles in paracrine islet regulation. Mol Cell Endocrinol. 2015;399:296-310 pubmed publisher
Wu Y, Guo X, Li C, Li D, Zhang J, Yang Y, et al. Dipeptidyl peptidase-4 inhibitor, vildagliptin, inhibits pancreatic beta cell apoptosis in association with its effects suppressing endoplasmic reticulum stress in db/db mice. Metabolism. 2015;64:226-35 pubmed publisher
de Ranitz Greven W, Beulens J, Hoeks L, Belle van Meerkerk G, Biesma D, de Valk H. Patients with type 2 diabetes mellitus failing on oral agents and starting once daily insulin regimen; a small randomized study investigating effects of adding vildagliptin. BMC Res Notes. 2014;7:579 pubmed publisher
Uc A, Olivier A, Griffin M, Meyerholz D, Yao J, Abu El Haija M, et al. Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass. Clin Sci (Lond). 2015;128:131-42 pubmed publisher
Wada R, Yagihashi S. The expression of glucagon-like peptide-1 receptor and dipeptidyl peptidase-IV in neuroendocrine neoplasms of the pancreas and gastrointestinal tract. Endocr Pathol. 2014;25:390-6 pubmed publisher
Miki A, Ricordi C, Yamamoto T, Sakuma Y, Misawa R, Mita A, et al. Improved human islet preparations using glucocorticoid and exendin-4. Pancreas. 2014;43:1317-22 pubmed publisher
Kim W, Fiori J, Shin Y, Okun E, Kim J, Rapp P, et al. Pancreatic polypeptide inhibits somatostatin secretion. FEBS Lett. 2014;588:3233-9 pubmed publisher
Ha B, Park J, Shin E, Shon Y. Modulation of glucose metabolism by balanced deep-sea water ameliorates hyperglycemia and pancreatic function in streptozotocin-induced diabetic mice. PLoS ONE. 2014;9:e102095 pubmed publisher
Yin D, You L, Yuan Q, Liang X, Wang N, Wang L, et al. Mesothelin promotes cell proliferation in the remodeling of neonatal rat pancreas. World J Gastroenterol. 2014;20:6884-96 pubmed publisher
Omar B, Liehua L, Yamada Y, Seino Y, Marchetti P, Ahren B. Dipeptidyl peptidase 4 (DPP-4) is expressed in mouse and human islets and its activity is decreased in human islets from individuals with type 2 diabetes. Diabetologia. 2014;57:1876-83 pubmed publisher
Blanco E, Peinado J, Martin M, Lindberg I. Biochemical and cell biological properties of the human prohormone convertase 1/3 Ser357Gly mutation: a PC1/3 hypermorph. Endocrinology. 2014;155:3434-47 pubmed publisher
Luo Y, He F, Hu L, Hai L, Huang M, Xu Z, et al. Transcription factor Ets1 regulates expression of thioredoxin-interacting protein and inhibits insulin secretion in pancreatic β-cells. PLoS ONE. 2014;9:e99049 pubmed publisher
Wewer Albrechtsen N, Hartmann B, Veedfald S, Windeløv J, Plamboeck A, Bojsen Møller K, et al. Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?. Diabetologia. 2014;57:1919-26 pubmed publisher
Pound L, Comstock S, Grove K. Consumption of a Western-style diet during pregnancy impairs offspring islet vascularization in a Japanese macaque model. Am J Physiol Endocrinol Metab. 2014;307:E115-23 pubmed publisher
Morris L, Days E, Turney M, Mi D, Lindsley C, Weaver C, et al. A Duplexed High-Throughput Screen to Identify Allosteric Modulators of the Glucagon-Like Peptide 1 and Glucagon Receptors. J Biomol Screen. 2014;19:847-58 pubmed publisher
O Malley T, Fava G, Zhang Y, Fonseca V, Wu H. Progressive change of intra-islet GLP-1 production during diabetes development. Diabetes Metab Res Rev. 2014;30:661-8 pubmed publisher
Glenn S, Jones C, Sexton S, LeVea C, Caraker S, Hajduczok G, et al. Conditional deletion of p53 and Rb in the renin-expressing compartment of the pancreas leads to a highly penetrant metastatic pancreatic neuroendocrine carcinoma. Oncogene. 2014;33:5706-15 pubmed publisher
Bruin J, Erener S, Vela J, Hu X, Johnson J, Kurata H, et al. Characterization of polyhormonal insulin-producing cells derived in vitro from human embryonic stem cells. Stem Cell Res. 2014;12:194-208 pubmed publisher
Holdcraft R, Gazda L, Circle L, Adkins H, Harbeck S, Meyer E, et al. Enhancement of in vitro and in vivo function of agarose-encapsulated porcine islets by changes in the islet microenvironment. Cell Transplant. 2014;23:929-44 pubmed publisher
Tamburro D, Fredolini C, Espina V, Douglas T, Ranganathan A, Ilag L, et al. Multifunctional core-shell nanoparticles: discovery of previously invisible biomarkers. J Am Chem Soc. 2011;133:19178-88 pubmed publisher
Harney J, Rodgers R. Insulin-like stimulation of cardiac fuel metabolism by physiological levels of glucagon: involvement of PI3K but not cAMP. Am J Physiol Endocrinol Metab. 2008;295:E155-61 pubmed publisher
Bernard S, Thil M, Groscolas R. Lipolytic and metabolic response to glucagon in fasting king penguins: phase II vs. phase III. Am J Physiol Regul Integr Comp Physiol. 2003;284:R444-54 pubmed
product information
Catalog Number :
G1774
Product Name :
Glucagon
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
≥95% (HPLC), powder, synthetic
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA