This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Forskolin
catalog :
F6886
citations: 625
Reference
Attane C, Estève D, Chaoui K, Iacovoni J, Corre J, Moutahir M, et al. Human Bone Marrow Is Comprised of Adipocytes with Specific Lipid Metabolism. Cell Rep. 2020;30:949-958.e6 pubmed publisher
Yoon H, Choi C, Triplet E, Langley M, Kleppe L, Kim H, et al. Blocking the Thrombin Receptor Promotes Repair of Demyelinated Lesions in the Adult Brain. J Neurosci. 2020;: pubmed publisher
Xu H, Dzhashiashvili Y, Shah A, Kunjamma R, Weng Y, Elbaz B, et al. m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination. Neuron. 2020;105:293-309.e5 pubmed publisher
Tang S, Yuen W, Kaur I, Pang S, Voelcker N, Lam Y. Capturing instructive cues of tissue microenvironment by silica bioreplication. Acta Biomater. 2020;102:114-126 pubmed publisher
Maffini M, Canatsey R. An expanded toxicological profile of tetramethyl bisphenol F (TMBPF), a precursor for a new food-contact metal packaging coating. Food Chem Toxicol. 2020;135:110889 pubmed publisher
Tozzi M, Hansen J, Novak I. Pannexin-1 mediated ATP release in adipocytes is sensitive to glucose and insulin and modulates lipolysis and macrophage migration. Acta Physiol (Oxf). 2020;228:e13360 pubmed publisher
Zamparo I, Francia S, Franchi S, Redolfi N, Costanzi E, Kerstens A, et al. Axonal Odorant Receptors Mediate Axon Targeting. Cell Rep. 2019;29:4334-4348.e7 pubmed publisher
Wang Y, Guo Y, Tang C, Han X, Xu M, Sun J, et al. Developmental Cytoplasmic-to-Nuclear Translocation of RNA-Binding Protein HuR Is Required for Adult Neurogenesis. Cell Rep. 2019;29:3101-3117.e7 pubmed publisher
Ma Z, Sagrillo Fagundes L, Tran R, Parameshwar P, Kalashnikov N, Vaillancourt C, et al. Biomimetic Micropatterned Adhesive Surfaces To Mechanobiologically Regulate Placental Trophoblast Fusion. ACS Appl Mater Interfaces. 2019;11:47810-47821 pubmed publisher
Wang J, Cui Y, Yu Z, Wang W, Cheng X, Ji W, et al. Brain Endothelial Cells Maintain Lactate Homeostasis and Control Adult Hippocampal Neurogenesis. Cell Stem Cell. 2019;25:754-767.e9 pubmed publisher
Périé L, Verma N, Xu L, Ma X, Mueller E. Transcriptional Regulation of ZNF638 in Thermogenic Cells by the cAMP Response Element Binding Protein in Male Mice. J Endocr Soc. 2019;3:2326-2340 pubmed publisher
Yang D, Zhang Q, Ma Y, Che Z, Zhang W, Wu M, et al. Augmenting the therapeutic efficacy of adenosine against pancreatic cancer by switching the Akt/p21-dependent senescence to apoptosis. EBioMedicine. 2019;47:114-127 pubmed publisher
Kwak S, Cho S, Bae J, Lee J, Shin H, Di Zhang D, et al. Effects of exercise-induced apelin on muscle function and cognitive function in aged mice. Exp Gerontol. 2019;127:110710 pubmed publisher
Braadland P, Ramberg H, Grytli H, Urbanucci A, Nielsen H, Guldvik I, et al. The β2-Adrenergic Receptor Is a Molecular Switch for Neuroendocrine Transdifferentiation of Prostate Cancer Cells. Mol Cancer Res. 2019;17:2154-2168 pubmed publisher
Nocita E, Del Giovane A, Tiberi M, Boccuni L, Fiorelli D, Sposato C, et al. EGFR/ErbB Inhibition Promotes OPC Maturation up to Axon Engagement by Co-Regulating PIP2 and MBP. Cells. 2019;8: pubmed publisher
Zaykov A, Gelfanov V, Perez Tilve D, Finan B, Dimarchi R. Insulin-like peptide 5 fails to improve metabolism or body weight in obese mice. Peptides. 2019;120:170116 pubmed publisher
Trogden K, Zhu X, Lee J, Wright C, Gu G, Kaverina I. Regulation of Glucose-Dependent Golgi-Derived Microtubules by cAMP/EPAC2 Promotes Secretory Vesicle Biogenesis in Pancreatic β Cells. Curr Biol. 2019;29:2339-2350.e5 pubmed publisher
Chen J, Zhang Y, Huang C, Shen H, Sun B, Cheng X, et al. m6A Regulates Neurogenesis and Neuronal Development by Modulating Histone Methyltransferase Ezh2. Genomics Proteomics Bioinformatics. 2019;: pubmed publisher
Guček A, Gandasi N, Omar Hmeadi M, Bakke M, Døskeland S, Tengholm A, et al. Fusion pore regulation by cAMP/Epac2 controls cargo release during insulin exocytosis. elife. 2019;8: pubmed publisher
Zhang X, Pathak T, Yoast R, Emrich S, Xin P, Nwokonko R, et al. A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction. Nat Commun. 2019;10:1971 pubmed publisher
Lotta L, Mokrosinski J, Mendes de Oliveira E, Li C, Sharp S, Luan J, et al. Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity. Cell. 2019;177:597-607.e9 pubmed publisher
Varum S, Baggiolini A, Zurkirchen L, Atak Z, Cantù C, Marzorati E, et al. Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation. Cell Stem Cell. 2019;24:637-653.e9 pubmed publisher
Xing B, Ma J, Jiang Z, Feng Z, Ling S, Szigety K, et al. GLP-1 signaling suppresses menin's transcriptional block by phosphorylation in β cells. J Cell Biol. 2019;218:855-870 pubmed publisher
Borczyk M, Sliwińska M, Caly A, Bernas T, Radwanska K. Neuronal plasticity affects correlation between the size of dendritic spine and its postsynaptic density. Sci Rep. 2019;9:1693 pubmed publisher
Siveen K, Prabhu K, Parray A, Merhi M, Arredouani A, Chikri M, et al. Evaluation of cationic channel TRPV2 as a novel biomarker and therapeutic target in Leukemia-Implications concerning the resolution of pulmonary inflammation. Sci Rep. 2019;9:1554 pubmed publisher
Feiner B, Chase K, Melbourne J, Rosen C, Sharma R. Risperidone effects on heterochromatin: the role of kinase signaling. Clin Exp Immunol. 2019;196:67-75 pubmed publisher
Peng Y, Shekhar K, Yan W, Herrmann D, Sappington A, Bryman G, et al. Molecular Classification and Comparative Taxonomics of Foveal and Peripheral Cells in Primate Retina. Cell. 2019;176:1222-1237.e22 pubmed publisher
Zadora P, Chumduri C, Imami K, Berger H, Mi Y, Selbach M, et al. Integrated Phosphoproteome and Transcriptome Analysis Reveals Chlamydia-Induced Epithelial-to-Mesenchymal Transition in Host Cells. Cell Rep. 2019;26:1286-1302.e8 pubmed publisher
Melamed Z, López Erauskin J, Baughn M, Zhang O, Drenner K, Sun Y, et al. Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration. Nat Neurosci. 2019;22:180-190 pubmed publisher
Manickam G, Moffatt P, Murshed M. Role of SMPD3 during Bone Fracture Healing and Regulation of Its Expression. Mol Cell Biol. 2019;39: pubmed publisher
Mo S, Cho Y, Choi B, Lee D, Kim H. PKA-dependent phosphorylation of IP3K-A at Ser119 regulates a binding affinity with EB3. Biochem Biophys Res Commun. 2019;508:52-59 pubmed publisher
Moon H, Javadi S, Stremlau M, Yoon K, Becker B, Kang S, et al. Conditioned media from AICAR-treated skeletal muscle cells increases neuronal differentiation of adult neural progenitor cells. Neuropharmacology. 2019;145:123-130 pubmed publisher
Su W, Wu F, Jin Z, Gu Y, Chen Y, Fei Y, et al. Overexpression of P2X4 receptor in Schwann cells promotes motor and sensory functional recovery and remyelination via BDNF secretion after nerve injury. Glia. 2019;67:78-90 pubmed publisher
Llorca Torralba M, Pilar Cuéllar F, Bravo L, Bruzos Cidon C, Torrecilla M, Mico J, et al. Opioid Activity in the Locus Coeruleus Is Modulated by Chronic Neuropathic Pain. Mol Neurobiol. 2019;56:4135-4150 pubmed publisher
Zhou Z, Hou J, Xiong J, Li M. Characterization of sulfuretin as a depigmenting agent. Fundam Clin Pharmacol. 2019;33:208-215 pubmed publisher
Xia E, Duan R, Shi F, Seigel K, Grasemann H, Hu J. Overcoming the Undesirable CRISPR-Cas9 Expression in Gene Correction. Mol Ther Nucleic Acids. 2018;13:699-709 pubmed publisher
Sun L, Mulinyawe S, Collins H, Ibrahim A, Li Q, Simon D, et al. Spatiotemporal Control of CNS Myelination by Oligodendrocyte Programmed Cell Death through the TFEB-PUMA Axis. Cell. 2018;175:1811-1826.e21 pubmed publisher
Zhang L, Ip C, Lee I, Qi Y, Reed F, Karl T, et al. Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling. Nat Commun. 2018;9:4722 pubmed publisher
Malcov Brog H, Alpert A, Golan T, Parikh S, Nordlinger A, Netti F, et al. UV-Protection Timer Controls Linkage between Stress and Pigmentation Skin Protection Systems. Mol Cell. 2018;72:444-456.e7 pubmed publisher
Blanco Suarez E, Liu T, Kopelevich A, Allen N. Astrocyte-Secreted Chordin-like 1 Drives Synapse Maturation and Limits Plasticity by Increasing Synaptic GluA2 AMPA Receptors. Neuron. 2018;100:1116-1132.e13 pubmed publisher
Plasschaert L, Zilionis R, Choo Wing R, Savova V, Knehr J, Roma G, et al. A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte. Nature. 2018;560:377-381 pubmed publisher
Schillemans M, Karampini E, van den Eshof B, Gangaev A, Hofman M, van Breevoort D, et al. Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells. Arterioscler Thromb Vasc Biol. 2018;38:1549-1561 pubmed publisher
Wei Z, Yoshihara E, He N, Hah N, Fan W, Pinto A, et al. Vitamin D Switches BAF Complexes to Protect β Cells. Cell. 2018;173:1135-1149.e15 pubmed publisher
Limpitikul W, Viswanathan M, O ROURKE B, Yue D, Cammarato A. Conservation of cardiac L-type Ca2+ channels and their regulation in Drosophila: A novel genetically-pliable channelopathic model. J Mol Cell Cardiol. 2018;119:64-74 pubmed publisher
Scheunemann L, Plaçais P, Dromard Y, Schwärzel M, Preat T. Dunce Phosphodiesterase Acts as a Checkpoint for Drosophila Long-Term Memory in a Pair of Serotonergic Neurons. Neuron. 2018;98:350-365.e5 pubmed publisher
Sato S, Ueno K, Saitoe M, Sakai T. Synaptic depression induced by postsynaptic cAMP production in the Drosophila mushroom body calyx. J Physiol. 2018;596:2447-2461 pubmed publisher
Perrin L, Loizides Mangold U, Chanon S, Gobet C, Hulo N, Isenegger L, et al. Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle. elife. 2018;7: pubmed publisher
Giralt A, Denechaud P, Lopez Mejia I, Delacuisine B, Blanchet E, Bonner C, et al. E2F1 promotes hepatic gluconeogenesis and contributes to hyperglycemia during diabetes. Mol Metab. 2018;11:104-112 pubmed publisher
Cao S, Dong X, Ho M, Yu W, Wong K, Yao X, et al. Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism. Nutrients. 2018;10: pubmed publisher
Bulgari D, Jha A, Deitcher D, Levitan E. Myopic (HD-PTP, PTPN23) selectively regulates synaptic neuropeptide release. Proc Natl Acad Sci U S A. 2018;115:1617-1622 pubmed publisher
Jacobs E, Warrier S, Volders P, D haene E, Van Lombergen E, Vantomme L, et al. CRISPR/Cas9-mediated genome editing in naïve human embryonic stem cells. Sci Rep. 2017;7:16650 pubmed publisher
Farhy Tselnicker I, van Casteren A, Lee A, Chang V, Aricescu A, Allen N. Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation. Neuron. 2017;96:428-445.e13 pubmed publisher
Yanda M, Liu Q, Cebotaru V, Guggino W, Cebotaru L. Histone deacetylase 6 inhibition reduces cysts by decreasing cAMP and Ca2+ in knock-out mouse models of polycystic kidney disease. J Biol Chem. 2017;292:17897-17908 pubmed publisher
Thomson S, Seo S, Barnes S, Louros S, Muscas M, Dando O, et al. Cell-Type-Specific Translation Profiling Reveals a Novel Strategy for Treating Fragile X Syndrome. Neuron. 2017;95:550-563.e5 pubmed publisher
Ayyadurai S, Gibson A, D Costa S, Overman E, Sommerville L, Poopal A, et al. Frontline Science: Corticotropin-releasing factor receptor subtype 1 is a critical modulator of mast cell degranulation and stress-induced pathophysiology. J Leukoc Biol. 2017;102:1299-1312 pubmed publisher
Vijay R, Fehr A, Janowski A, Athmer J, Wheeler D, Grunewald M, et al. Virus-induced inflammasome activation is suppressed by prostaglandin D2/DP1 signaling. Proc Natl Acad Sci U S A. 2017;114:E5444-E5453 pubmed publisher
Semenova G, Stepanova D, Dubyk C, Handorf E, Deyev S, Lazar A, et al. Targeting group I p21-activated kinases to control malignant peripheral nerve sheath tumor growth and metastasis. Oncogene. 2017;36:5421-5431 pubmed publisher
Schott M, Rasineni K, Weller S, Schulze R, Sletten A, Casey C, et al. ?-Adrenergic induction of lipolysis in hepatocytes is inhibited by ethanol exposure. J Biol Chem. 2017;292:11815-11828 pubmed publisher
Kriszt R, Arai S, Itoh H, Lee M, Goralczyk A, Ang X, et al. Optical visualisation of thermogenesis in stimulated single-cell brown adipocytes. Sci Rep. 2017;7:1383 pubmed publisher
Butler T, Pater J, MacPhee D. Integrin linked kinase regulates syncytialization of BeWo trophoblast cells. Biol Reprod. 2017;96:673-685 pubmed publisher
Daumas S, Hunter C, Mistry R, Morè L, Privitera L, Cooper D, et al. The Kinase Function of MSK1 Regulates BDNF Signaling to CREB and Basal Synaptic Transmission, But Is Not Required for Hippocampal Long-Term Potentiation or Spatial Memory. Eneuro. 2017;4: pubmed publisher
Han X, Li P, Yang Z, Huang X, Wei G, Sun Y, et al. Zyxin regulates endothelial von Willebrand factor secretion by reorganizing actin filaments around exocytic granules. Nat Commun. 2017;8:14639 pubmed publisher
Heffernan C, Jain M, Liu T, Kim H, Barretto K, Li H, et al. Nectin-like 4 Complexes with Choline Transporter-like Protein-1 and Regulates Schwann Cell Choline Homeostasis and Lipid Biogenesis in Vitro. J Biol Chem. 2017;292:4484-4498 pubmed publisher
Keir L, Firth R, Aponik L, Feitelberg D, Sakimoto S, Aguilar E, et al. VEGF regulates local inhibitory complement proteins in the eye and kidney. J Clin Invest. 2017;127:199-214 pubmed publisher
Wein M, Liang Y, Göransson O, Sundberg T, Wang J, Williams E, et al. SIKs control osteocyte responses to parathyroid hormone. Nat Commun. 2016;7:13176 pubmed publisher
Sun J, Ye X, Xie M, Ye J. Induction of triglyceride accumulation and mitochondrial maintenance in muscle cells by lactate. Sci Rep. 2016;6:33732 pubmed publisher
Ayres Pereira M, Mandel Clausen T, Pehrson C, Mao Y, Resende M, Daugaard M, et al. Placental Sequestration of Plasmodium falciparum Malaria Parasites Is Mediated by the Interaction Between VAR2CSA and Chondroitin Sulfate A on Syndecan-1. PLoS Pathog. 2016;12:e1005831 pubmed publisher
Fernando R, Cotter L, Perrin Tricaud C, Berthelot J, Bartolami S, Pereira J, et al. Optimal myelin elongation relies on YAP activation by axonal growth and inhibition by Crb3/Hippo pathway. Nat Commun. 2016;7:12186 pubmed publisher
Barquilla A, Lamberto I, Noberini R, Heynen Genel S, Brill L, Pasquale E. Protein kinase A can block EphA2 receptor-mediated cell repulsion by increasing EphA2 S897 phosphorylation. Mol Biol Cell. 2016;27:2757-70 pubmed publisher
Choi M, Kim H, Ham M, Choi D, Lee T, Shin D. Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal Degradation in Differentiated Adipocytes. Sci Rep. 2016;6:28476 pubmed publisher
Akhmedov D, Rajendran K, Mendoza Rodriguez M, Berdeaux R. Knock-in Luciferase Reporter Mice for In Vivo Monitoring of CREB Activity. PLoS ONE. 2016;11:e0158274 pubmed publisher
Xiong L, Xia W, Tang F, Pan J, Mei L, Xiong W. Retromer in Osteoblasts Interacts With Protein Phosphatase 1 Regulator Subunit 14C, Terminates Parathyroid Hormone's Signaling, and Promotes Its Catabolic Response. EBioMedicine. 2016;9:45-60 pubmed publisher
Kuramoto K, Wang N, Fan Y, Zhang W, Schoenen F, Frankowski K, et al. Autophagy activation by novel inducers prevents BECN2-mediated drug tolerance to cannabinoids. Autophagy. 2016;12:1460-71 pubmed publisher
Hao Y, Frey E, Yoon C, Wong H, Nestorovski D, Holzman L, et al. An evolutionarily conserved mechanism for cAMP elicited axonal regeneration involves direct activation of the dual leucine zipper kinase DLK. elife. 2016;5: pubmed publisher
Lorenz C, Opitz R, Trubiroha A, Lutz I, Ziková A, Kloas W. The synthetic gestagen levonorgestrel directly affects gene expression in thyroid and pituitary glands of Xenopus laevis tadpoles. Aquat Toxicol. 2016;177:63-73 pubmed publisher
Kong X, Zhang D, Zhuang W, Hua S, Dai Y, Yuan Y, et al. AKAP95 promotes cell cycle progression via interactions with cyclin E and low molecular weight cyclin E. Am J Transl Res. 2016;8:811-26 pubmed
Gao F, Li T, Hu J, Zhou X, Wu J, Wu Q. Comparative analysis of three purification protocols for retinal ganglion cells from rat. Mol Vis. 2016;22:387-400 pubmed
Hattori K, Naguro I, Okabe K, Funatsu T, Furutani S, Takeda K, et al. ASK1 signalling regulates brown and beige adipocyte function. Nat Commun. 2016;7:11158 pubmed publisher
Tosco A, De Gregorio F, Esposito S, De Stefano D, Sana I, Ferrari E, et al. A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR. Cell Death Differ. 2016;23:1380-93 pubmed publisher
Tosoni K, Cassidy D, Kerr B, Land S, Mehta A. Using Drugs to Probe the Variability of Trans-Epithelial Airway Resistance. PLoS ONE. 2016;11:e0149550 pubmed publisher
Lee M, Goralczyk A, Kriszt R, Ang X, Badowski C, Li Y, et al. ECM microenvironment unlocks brown adipogenic potential of adult human bone marrow-derived MSCs. Sci Rep. 2016;6:21173 pubmed publisher
Chen X, Kong X, Zhuang W, Teng B, Yu X, Hua S, et al. Dynamic changes in protein interaction between AKAP95 and Cx43 during cell cycle progression of A549 cells. Sci Rep. 2016;6:21224 pubmed publisher
Park Y, Broyles H, He S, McGrady N, Li L, Yorio T. Involvement of AMPA Receptor and Its Flip and Flop Isoforms in Retinal Ganglion Cell Death Following Oxygen/Glucose Deprivation. Invest Ophthalmol Vis Sci. 2016;57:508-26 pubmed publisher
Latif R, Lau Z, Cheung P, Felsenfeld D, Davies T. The "TSH Receptor Glo Assay" - A High-Throughput Detection System for Thyroid Stimulation. Front Endocrinol (Lausanne). 2016;7:3 pubmed publisher
Greenwood M, Greenwood M, Gillard B, Loh S, Paton J, Murphy D. Epigenetic Control of the Vasopressin Promoter Explains Physiological Ability to Regulate Vasopressin Transcription in Dehydration and Salt Loading States in the Rat. J Neuroendocrinol. 2016;28: pubmed publisher
Torres G, Morales P, García Miguel M, Norambuena Soto I, Cartes Saavedra B, Vidal Peña G, et al. Glucagon-like peptide-1 inhibits vascular smooth muscle cell dedifferentiation through mitochondrial dynamics regulation. Biochem Pharmacol. 2016;104:52-61 pubmed publisher
Chávez Vargas L, Adame García S, Cervantes Villagrana R, Castillo Kauil A, Bruystens J, Fukuhara S, et al. Protein Kinase A (PKA) Type I Interacts with P-Rex1, a Rac Guanine Nucleotide Exchange Factor: EFFECT ON PKA LOCALIZATION AND P-Rex1 SIGNALING. J Biol Chem. 2016;291:6182-99 pubmed publisher
Greenwood M, Greenwood M, Mecawi A, Antunes Rodrigues J, Paton J, Murphy D. Rasd1, a small G protein with a big role in the hypothalamic response to neuronal activation. Mol Brain. 2016;9:1 pubmed publisher
Maícas Royo J, Brown C, Leng G, MacGregor D. Oxytocin Neurones: Intrinsic Mechanisms Governing the Regularity of Spiking Activity. J Neuroendocrinol. 2016;28: pubmed publisher
Foulke Abel J, In J, Yin J, Zachos N, Kovbasnjuk O, Estes M, et al. Human Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology. Gastroenterology. 2016;150:638-649.e8 pubmed publisher
Visser J, Cheng Y, Perry S, Chastain A, Parsa B, Masri S, et al. An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina. elife. 2015;4:e08149 pubmed publisher
Ishimoto T, Azechi K, Mori H. Identification of a Novel Protein Kinase A Inhibitor by Bioluminescence-Based Screening. Biol Pharm Bull. 2015;38:1969-74 pubmed publisher
Asano T, Aida S, Suemasu S, Tahara K, Tanaka K, Mizushima T. Aldioxa improves delayed gastric emptying and impaired gastric compliance, pathophysiologic mechanisms of functional dyspepsia. Sci Rep. 2015;5:17519 pubmed publisher
Koh S, Kim N, Yin H, Harris I, Dejneka N, Eroglu C. Human Umbilical Tissue-Derived Cells Promote Synapse Formation and Neurite Outgrowth via Thrombospondin Family Proteins. J Neurosci. 2015;35:15649-65 pubmed publisher
Bitam S, Pranke I, Hollenhorst M, Servel N, Moquereau C, Tondelier D, et al. An unexpected effect of TNF-α on F508del-CFTR maturation and function. F1000Res. 2015;4:218 pubmed publisher
Pon C, Lane J, Sloan E, Halls M. The β2-adrenoceptor activates a positive cAMP-calcium feedforward loop to drive breast cancer cell invasion. FASEB J. 2016;30:1144-54 pubmed publisher
Sluch V, Davis C, Ranganathan V, Kerr J, Krick K, Martin R, et al. Differentiation of human ESCs to retinal ganglion cells using a CRISPR engineered reporter cell line. Sci Rep. 2015;5:16595 pubmed publisher
Crites K, Morin G, Orlando V, Patey N, Cantin C, Martel J, et al. CFTR Knockdown induces proinflammatory changes in intestinal epithelial cells. J Inflamm (Lond). 2015;12:62 pubmed publisher
Grimm F, Iwata Y, Sirenko O, Bittner M, Rusyn I. High-Content Assay Multiplexing for Toxicity Screening in Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Hepatocytes. Assay Drug Dev Technol. 2015;13:529-46 pubmed publisher
Rao S, Morales A, Pearse D. The Comparative Utility of Viromer RED and Lipofectamine for Transient Gene Introduction into Glial Cells. Biomed Res Int. 2015;2015:458624 pubmed publisher
Raju G, Ram Reddy A. Potential benefits of triethylamine as n-electron donor in the estimation of forskolin by electronic absorption and emission spectroscopy. Spectrochim Acta A Mol Biomol Spectrosc. 2016;154:84-88 pubmed publisher
Wands A, Fujita A, McCombs J, Cervin J, Dedic B, Rodriguez A, et al. Fucosylation and protein glycosylation create functional receptors for cholera toxin. elife. 2015;4:e09545 pubmed publisher
Chen O, Wu M, Jiang L. The Effect of Hypoxic Preconditioning on Induced Schwann Cells under Hypoxic Conditions. PLoS ONE. 2015;10:e0141201 pubmed publisher
Bozkurt A, Boecker A, Tank J, Altinova H, Deumens R, Dabhi C, et al. Efficient bridging of 20 mm rat sciatic nerve lesions with a longitudinally micro-structured collagen scaffold. Biomaterials. 2016;75:112-122 pubmed publisher
Hopper A, Dugan J, Gill A, Regan E, Haycock J, Kelly S, et al. Photochemically modified diamond-like carbon surfaces for neural interfaces. Mater Sci Eng C Mater Biol Appl. 2016;58:1199-206 pubmed publisher
Gökbuget D, Pereira J, Bachofner S, Marchais A, Ciaudo C, Stoffel M, et al. The Lin28/let-7 axis is critical for myelination in the peripheral nervous system. Nat Commun. 2015;6:8584 pubmed publisher
Bhattacharya S, Imbery J, Ampem P, Giovannucci D. Crosstalk between purinergic receptors and canonical signaling pathways in the mouse salivary gland. Cell Calcium. 2015;58:589-97 pubmed publisher
Gertzen C, Spomer L, Smits S, Häussinger D, Keitel V, Gohlke H. Mutational mapping of the transmembrane binding site of the G-protein coupled receptor TGR5 and binding mode prediction of TGR5 agonists. Eur J Med Chem. 2015;104:57-72 pubmed publisher
Yoshizaki Y, Mori Y, Tsuzaki Y, Mori T, Nomura N, Wakabayashi M, et al. Impaired degradation of WNK by Akt and PKA phosphorylation of KLHL3. Biochem Biophys Res Commun. 2015;467:229-34 pubmed publisher
Roxo Rosa M, Jacinto R, Sampaio P, Lopes S. The zebrafish Kupffer's vesicle as a model system for the molecular mechanisms by which the lack of Polycystin-2 leads to stimulation of CFTR. Biol Open. 2015;4:1356-66 pubmed publisher
Shi Q, Yin Z, Zhao B, Sun F, Yu H, Yin X, et al. PGE2 Elevates IL-23 Production in Human Dendritic Cells via a cAMP Dependent Pathway. Mediators Inflamm. 2015;2015:984690 pubmed publisher
Andersen M, Hefting L, Steffensen A, Schmitt N, Olesen S, Olsen J, et al. Protein kinase A stimulates Kv7.1 surface expression by regulating Nedd4-2-dependent endocytic trafficking. Am J Physiol Cell Physiol. 2015;309:C693-706 pubmed publisher
Liu N, Wei K, Xun Y, Yang X, Gan S, Xiao H, et al. Transcription factor cyclic adenosine monophosphate responsive element binding protein negatively regulates tumor necrosis factor alpha-induced protein 1 expression. Mol Med Rep. 2015;12:7763-9 pubmed publisher
Nayak S, Khan M, Wan T, Pei H, Linden J, Dwinell M, et al. Characterization of Dahl salt-sensitive rats with genetic disruption of the A2B adenosine receptor gene: implications for A2B adenosine receptor signaling during hypertension. Purinergic Signal. 2015;11:519-31 pubmed publisher
Schuh C, Morton T, Banerjee A, Grasl C, Schima H, Schmidhammer R, et al. Activated Schwann Cell-Like Cells on Aligned Fibrin-Poly(Lactic-Co-Glycolic Acid) Structures: A Novel Construct for Application in Peripheral Nerve Regeneration. Cells Tissues Organs. 2015;200:287-99 pubmed publisher
Tseng H, Gage J, Shen T, Haisler W, Neeley S, Shiao S, et al. A spheroid toxicity assay using magnetic 3D bioprinting and real-time mobile device-based imaging. Sci Rep. 2015;5:13987 pubmed publisher
Mastrototaro L, Tietjen U, Sponder G, Vormann J, Aschenbach J, Kolisek M. Insulin Modulates the Na+/Mg2+ Exchanger SLC41A1 and Influences Mg2+ Efflux from Intracellular Stores in Transgenic HEK293 Cells. J Nutr. 2015;145:2440-7 pubmed publisher
Yao H, Gao M, Ma J, Zhang M, Li S, Wu B, et al. Transdifferentiation-Induced Neural Stem Cells Promote Recovery of Middle Cerebral Artery Stroke Rats. PLoS ONE. 2015;10:e0137211 pubmed publisher
Hayashi Takagi A, Yagishita S, Nakamura M, Shirai F, Wu Y, Loshbaugh A, et al. Labelling and optical erasure of synaptic memory traces in the motor cortex. Nature. 2015;525:333-8 pubmed publisher
Yukiura H, Kano K, Kise R, Inoue A, Aoki J. LPP3 localizes LPA6 signalling to non-contact sites in endothelial cells. J Cell Sci. 2015;128:3871-7 pubmed publisher
Lim S, Haque M, Nam G, Ryoo N, Rhim H, Kim Y. Monitoring of Intracellular Tau Aggregation Regulated by OGA/OGT Inhibitors. Int J Mol Sci. 2015;16:20212-24 pubmed publisher
Regazzetti C, Joly F, Marty C, Rivier M, Mehul B, Reiniche P, et al. Transcriptional Analysis of Vitiligo Skin Reveals the Alteration of WNT Pathway: A Promising Target for Repigmenting Vitiligo Patients. J Invest Dermatol. 2015;135:3105-3114 pubmed publisher
Hao Y, Cheung C, Yip W, Ko W. Nobiletin Stimulates Chloride Secretion in Human Bronchial Epithelia via a cAMP/PKA-Dependent Pathway. Cell Physiol Biochem. 2015;37:306-20 pubmed publisher
Chang H, Young S, Sinnett Smith J, Chou C, Moro A, Hertzer K, et al. Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1. Am J Physiol Cell Physiol. 2015;309:C639-49 pubmed publisher
Regazzetti C, De Donatis G, Ghorbel H, Cardot Leccia N, Ambrosetti D, Bahadoran P, et al. Endothelial Cells Promote Pigmentation through Endothelin Receptor B Activation. J Invest Dermatol. 2015;135:3096-3104 pubmed publisher
Simpson M, Venkatesh I, Callif B, Thiel L, Coley D, Winsor K, et al. The tumor suppressor HHEX inhibits axon growth when prematurely expressed in developing central nervous system neurons. Mol Cell Neurosci. 2015;68:272-83 pubmed publisher
Follin Arbelet V, Misund K, Naderi E, Ugland H, Sundan A, Blomhoff H. The natural compound forskolin synergizes with dexamethasone to induce cell death in myeloma cells via BIM. Sci Rep. 2015;5:13001 pubmed publisher
Meir M, Flemming S, Burkard N, Bergauer L, Metzger M, Germer C, et al. Glial cell line-derived neurotrophic factor promotes barrier maturation and wound healing in intestinal epithelial cells in vitro. Am J Physiol Gastrointest Liver Physiol. 2015;309:G613-24 pubmed publisher
Cabral J, Grácio D, Soares da Silva P, Magro F. Short- and long-term regulation of intestinal Na+/H+ exchange by Toll-like receptors TLR4 and TLR5. Am J Physiol Gastrointest Liver Physiol. 2015;309:G703-15 pubmed publisher
Dittrich N, Kummer W, Clauss W, Fronius M. Luminal acetylcholine does not affect the activity of the CFTR in tracheal epithelia of pigs. Int Immunopharmacol. 2015;29:166-72 pubmed publisher
Onimaru K, Kuraku S, Takagi W, Hyodo S, Sharpe J, Tanaka M. A shift in anterior-posterior positional information underlies the fin-to-limb evolution. elife. 2015;4: pubmed publisher
Vencappa S, Donaldson L, Hulse R. Cisplatin induced sensory neuropathy is prevented by vascular endothelial growth factor-A. Am J Transl Res. 2015;7:1032-44 pubmed
Muñoz Llancao P, Henríquez D, Wilson C, Bodaleo F, Boddeke E, Lezoualc h F, et al. Exchange Protein Directly Activated by cAMP (EPAC) Regulates Neuronal Polarization through Rap1B. J Neurosci. 2015;35:11315-29 pubmed publisher
Wróbel A, Gregoraszczuk E. Action of methyl-, propyl- and butylparaben on GPR30 gene and protein expression, cAMP levels and activation of ERK1/2 and PI3K/Akt signaling pathways in MCF-7 breast cancer cells and MCF-10A non-transformed breast epithelial cells. Toxicol Lett. 2015;238:110-6 pubmed publisher
Cheng L, Wu Q, Kortenoeven M, Pisitkun T, Fenton R. A Systems Level Analysis of Vasopressin-mediated Signaling Networks in Kidney Distal Convoluted Tubule Cells. Sci Rep. 2015;5:12829 pubmed publisher
Tian C, Li Y, Huang Y, Wang Y, Chen D, Liu J, et al. Selective Generation of Dopaminergic Precursors from Mouse Fibroblasts by Direct Lineage Conversion. Sci Rep. 2015;5:12622 pubmed publisher
Weaver E, Zamora F, Hearne J, Martin Caraballo M. Posttranscriptional regulation of T-type Ca(2+) channel expression by interleukin-6 in prostate cancer cells. Cytokine. 2015;76:309-320 pubmed publisher
Balseiro Gomez S, Flores J, Acosta J, Ramirez Ponce M, Ales E. Identification of a New Exo-Endocytic Mechanism Triggered by Corticotropin-Releasing Hormone in Mast Cells. J Immunol. 2015;195:2046-56 pubmed publisher
Lucas S, Armstrong D. Protein phosphatase modulation of somatostatin receptor signaling in the mouse hippocampus. Neuropharmacology. 2015;99:232-41 pubmed publisher
Bamidele A, Kremer K, Hirsova P, Clift I, Gores G, Billadeau D, et al. IQGAP1 promotes CXCR4 chemokine receptor function and trafficking via EEA-1+ endosomes. J Cell Biol. 2015;210:257-72 pubmed publisher
Tomati V, Sondo E, Armirotti A, Caci E, Pesce E, Marini M, et al. Genetic Inhibition Of The Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated To F508del Cystic Fibrosis Mutation. Sci Rep. 2015;5:12138 pubmed publisher
Russo R, Adornetto A, Cavaliere F, Varano G, Rusciano D, Morrone L, et al. Intravitreal injection of forskolin, homotaurine, and L-carnosine affords neuroprotection to retinal ganglion cells following retinal ischemic injury. Mol Vis. 2015;21:718-29 pubmed
Ma J, Cui B, Ding X, Wei J, Cui L. Over-Expression of Cyclin D1 Promotes NSCs Proliferation and Induces the Differentiation into Astrocytes Via Jak-STAT3 Pathways. Neurochem Res. 2015;40:1681-90 pubmed publisher
Wong K, Lai Y, Li K, Lee K, Ng T, Cheung H, et al. A Novel, Stable, Estradiol-Stimulating, Osteogenic Yam Protein with Potential for the Treatment of Menopausal Syndrome. Sci Rep. 2015;5:10179 pubmed publisher
Kamikubo Y, Tabata T, Sakairi H, Hashimoto Y, Sakurai T. Complex formation and functional interaction between adenosine A1 receptor and type-1 metabotropic glutamate receptor. J Pharmacol Sci. 2015;128:125-30 pubmed publisher
Bazley F, Liu C, Yuan X, Hao H, All A, De Los Angeles A, et al. Direct Reprogramming of Human Primordial Germ Cells into Induced Pluripotent Stem Cells: Efficient Generation of Genetically Engineered Germ Cells. Stem Cells Dev. 2015;24:2634-48 pubmed publisher
Krajcs N, Hernádi L, Pirger Z, Reglődi D, Tóth G, Kiss T. PACAP Modulates Acetylcholine-Elicited Contractions at Nicotinic Neuromuscular Contacts of the Land Snail. J Mol Neurosci. 2015;57:492-500 pubmed publisher
Chang S, Mascarella S, Spangler S, Gurevich V, Navarro H, Carroll F, et al. Quantitative Signaling and Structure-Activity Analyses Demonstrate Functional Selectivity at the Nociceptin/Orphanin FQ Opioid Receptor. Mol Pharmacol. 2015;88:502-11 pubmed publisher
Kappos E, Engels P, Tremp M, Meyer Zu Schwabedissen M, di Summa P, Fischmann A, et al. Peripheral Nerve Repair: Multimodal Comparison of the Long-Term Regenerative Potential of Adipose Tissue-Derived Cells in a Biodegradable Conduit. Stem Cells Dev. 2015;24:2127-41 pubmed publisher
Kumar P, Bhattacharyya S, Peters K, Glover M, Sen A, Cox R, et al. miR-16 rescues F508del-CFTR function in native cystic fibrosis epithelial cells. Gene Ther. 2015;22:908-16 pubmed publisher
Cheng F, Sawant T, Lan K, Lu C, Jung J, Gao S. Screening of the Human Kinome Identifies MSK1/2-CREB1 as an Essential Pathway Mediating Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication during Primary Infection. J Virol. 2015;89:9262-80 pubmed publisher
Moraes M, Ramos B, Poletini M, Castrucci A. Melanopsins: Localization and Phototransduction in Xenopus laevis Melanophores. Photochem Photobiol. 2015;91:1133-41 pubmed publisher
Duggal G, Warrier S, Ghimire S, Broekaert D, Van der Jeught M, Lierman S, et al. Alternative Routes to Induce Naïve Pluripotency in Human Embryonic Stem Cells. Stem Cells. 2015;33:2686-98 pubmed publisher
Theodorou M, Rauser B, Zhang J, Prakash N, Wurst W, Schick J. Limitations of In Vivo Reprogramming to Dopaminergic Neurons via a Tricistronic Strategy. Hum Gene Ther Methods. 2015;26:107-22 pubmed publisher
Kaitu u Lino T, Tong S, Beard S, Hastie R, Tuohey L, Brownfoot F, et al. Characterization of protocols for primary trophoblast purification, optimized for functional investigation of sFlt-1 and soluble endoglin. Pregnancy Hypertens. 2014;4:287-95 pubmed publisher
Watson R, Buck J, Levin L, Winger R, Wang J, Arase H, et al. Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration. J Exp Med. 2015;212:1021-41 pubmed publisher
Tonazzini I, Jacchetti E, Meucci S, Beltram F, Cecchini M. Schwann Cell Contact Guidance versus Boundary -Interaction in Functional Wound Healing along Nano and Microstructured Membranes. Adv Healthc Mater. 2015;4:1849-60 pubmed publisher
Diraddo J, Miller E, Bowman Dalley C, Wroblewska B, Javidnia M, Grajkowska E, et al. Chloride is an Agonist of Group II and III Metabotropic Glutamate Receptors. Mol Pharmacol. 2015;88:450-9 pubmed publisher
D Osualdo A, Anania V, Yu K, Lill J, Kaufman R, Matsuzawa S, et al. Transcription Factor ATF4 Induces NLRP1 Inflammasome Expression during Endoplasmic Reticulum Stress. PLoS ONE. 2015;10:e0130635 pubmed publisher
Khan D, Guillemette C, Sirard M, Richard F. Transcriptomic analysis of cyclic AMP response in bovine cumulus cells. Physiol Genomics. 2015;47:432-42 pubmed publisher
Stroth N, Niso M, Colabufo N, Perrone R, Svenningsson P, Lacivita E, et al. Arylpiperazine agonists of the serotonin 5-HT1A receptor preferentially activate cAMP signaling versus recruitment of β-arrestin-2. Bioorg Med Chem. 2015;23:4824-30 pubmed publisher
Kottler V, Künstner A, Koch I, Flötenmeyer M, Langenecker T, Hoffmann M, et al. Adenylate cyclase 5 is required for melanophore and male pattern development in the guppy (Poecilia reticulata). Pigment Cell Melanoma Res. 2015;28:545-58 pubmed publisher
Nicol L, Dawes J, La Russa F, Didangelos A, Clark A, Gentry C, et al. The role of G-protein receptor 84 in experimental neuropathic pain. J Neurosci. 2015;35:8959-69 pubmed publisher
Gnavi S, Fornasari B, Tonda Turo C, Laurano R, Zanetti M, Ciardelli G, et al. The Effect of Electrospun Gelatin Fibers Alignment on Schwann Cell and Axon Behavior and Organization in the Perspective of Artificial Nerve Design. Int J Mol Sci. 2015;16:12925-42 pubmed publisher
. Rp-cAMPS Prodrugs Reveal the cAMP Dependence of First-Phase Glucose-Stimulated Insulin Secretion. Mol Endocrinol. 2015;29:988-1005 pubmed publisher
Guo X, Li S, Ji Q, Lian R, Chen J. Enhanced viability and neural differential potential in poor post-thaw hADSCs by agarose multi-well dishes and spheroid culture. Hum Cell. 2015;28:175-89 pubmed publisher
Lesiak A, Brodsky M, Neumaier J. RiboTag is a flexible tool for measuring the translational state of targeted cells in heterogeneous cell cultures. Biotechniques. 2015;58:308-17 pubmed publisher
Polari L, Yatkin E, Martínez Chacón M, Ahotupa M, Smeds A, Strauss L, et al. Weight gain and inflammation regulate aromatase expression in male adipose tissue, as evidenced by reporter gene activity. Mol Cell Endocrinol. 2015;412:123-30 pubmed publisher
Peng J, Xin H, Han P, Gao K, Gao T, Lei Y, et al. Expression and regulative function of tissue inhibitor of metalloproteinase 3 in the goat ovary and its role in cultured granulosa cells. Mol Cell Endocrinol. 2015;412:104-15 pubmed publisher
Malhotra S, Suman P, Gupta S. Alpha or beta human chorionic gonadotropin knockdown decrease BeWo cell fusion by down-regulating PKA and CREB activation. Sci Rep. 2015;5:11210 pubmed publisher
Loong B, Tan J, Lim K, Mbaki Y, Ting K. Contractile function of smooth muscle retained after overnight storage. Naunyn Schmiedebergs Arch Pharmacol. 2015;388:1061-7 pubmed publisher
Arana M, Tocchetti G, Domizi P, Arias A, Rigalli J, Ruiz M, et al. Coordinated induction of GST and MRP2 by cAMP in Caco-2 cells: Role of protein kinase A signaling pathway and toxicological relevance. Toxicol Appl Pharmacol. 2015;287:178-90 pubmed publisher
Itoh Y, Sanosaka M, Fuchino H, Yahara Y, Kumagai A, Takemoto D, et al. Salt-inducible Kinase 3 Signaling Is Important for the Gluconeogenic Programs in Mouse Hepatocytes. J Biol Chem. 2015;290:17879-93 pubmed publisher
Dong B, Tu G, Han Y, Chen Y. Lithium enhanced cell proliferation and differentiation of mesenchymal stem cells to neural cells in rat spinal cord. Int J Clin Exp Pathol. 2015;8:2473-83 pubmed
Daigle M, Roumaud P, Martin L. Expressions of Sox9, Sox5, and Sox13 transcription factors in mice testis during postnatal development. Mol Cell Biochem. 2015;407:209-21 pubmed publisher
Li Z, Liu X, Liu Y, Xue Y, Wang P, Liu L, et al. Functions for the cAMP/Epac/Rap1 Signaling Pathway in Low-Dose Endothelial Monocyte-Activating Polypeptide-II-Induced Opening of Blood-Tumor Barrier. J Mol Neurosci. 2015;57:1-10 pubmed publisher
Chen Y, Zhang J, Shen L, Qi Q, Cheng X, Zhong Z, et al. Schwann cells induce Proliferation and Migration of Oligodendrocyte Precursor Cells Through Secretion of PDGF-AA and FGF-2. J Mol Neurosci. 2015;56:999-1008 pubmed publisher
Khajehali E, Malone D, Glass M, Sexton P, Christopoulos A, Leach K. Biased Agonism and Biased Allosteric Modulation at the CB1 Cannabinoid Receptor. Mol Pharmacol. 2015;88:368-79 pubmed publisher
Hernandez J, Chang C, Leblanc M, Grimm D, Le Lay J, Kaestner K, et al. The CREB/CRTC2 pathway modulates autoimmune disease by promoting Th17 differentiation. Nat Commun. 2015;6:7216 pubmed publisher
Brayden D, Maher S, Bahar B, Walsh E. Sodium caprate-induced increases in intestinal permeability and epithelial damage are prevented by misoprostol. Eur J Pharm Biopharm. 2015;94:194-206 pubmed publisher
Rosa E, Fahnestock M. CREB expression mediates amyloid ?-induced basal BDNF downregulation. Neurobiol Aging. 2015;36:2406-13 pubmed publisher
Franz D, Contreras F, González H, Prado C, Elgueta D, Figueroa C, et al. Dopamine receptors D3 and D5 regulate CD4(+)T-cell activation and differentiation by modulating ERK activation and cAMP production. J Neuroimmunol. 2015;284:18-29 pubmed publisher
Kim E, Jeon H, Lim H, Shin J, Park S, Jo Y, et al. Conditioned Media from Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Inhibits Melanogenesis by Promoting Proteasomal Degradation of MITF. PLoS ONE. 2015;10:e0128078 pubmed publisher
Tzekova N, Heinen A, Bunk S, Hermann C, Hartung H, Reipert B, et al. Immunoglobulins stimulate cultured Schwann cell maturation and promote their potential to induce axonal outgrowth. J Neuroinflammation. 2015;12:107 pubmed publisher
Illing E, Cho D, Zhang S, Skinner D, Dunlap Q, Sorscher E, et al. Chlorogenic Acid Activates CFTR-Mediated Cl- Secretion in Mice and Humans: Therapeutic Implications for Chronic Rhinosinusitis. Otolaryngol Head Neck Surg. 2015;153:291-7 pubmed publisher
Kaneda T, Saito E, Kanda H, Urakawa N, Shimizu K. Effects of papaverine on carbachol- and high K+ -induced contraction in the bovine abomasum. J Vet Med Sci. 2015;77:1269-74 pubmed publisher
Trescos Y, Tessier E, Rougeaux C, Goossens P, Tournier J. Micropatterned macrophage analysis reveals global cytoskeleton constraints induced by Bacillus anthracis edema toxin. Infect Immun. 2015;83:3114-25 pubmed publisher
Qiu L, He B, Hu J, Zhu Z, Liu X, Zhu J. Cartilage Oligomeric Matrix Protein Angiopoeitin-1 Provides Benefits During Nerve Regeneration In Vivo and In Vitro. Ann Biomed Eng. 2015;43:2924-40 pubmed publisher
Canal C, Felsing D, Liu Y, Zhu W, Wood J, Perry C, et al. An Orally Active Phenylaminotetralin-Chemotype Serotonin 5-HT7 and 5-HT1A Receptor Partial Agonist that Corrects Motor Stereotypy in Mouse Models. ACS Chem Neurosci. 2015;6:1259-70 pubmed publisher
Iessi E, Zischler L, Etringer A, Bergeret M, Morlé A, Jacquemin G, et al. Death Receptor-Induced Apoptosis Signalling Regulation by Ezrin Is Cell Type Dependent and Occurs in a DISC-Independent Manner in Colon Cancer Cells. PLoS ONE. 2015;10:e0126526 pubmed publisher
Gillespie J, Rouget C, Palea S, Granato C, Birder L, Korstanje C. The characteristics of intrinsic complex micro-contractile activity in isolated strips of the rat bladder. Naunyn Schmiedebergs Arch Pharmacol. 2015;388:709-18 pubmed publisher
Mishra B, Park J, Wilson K, Jo M. X-linked lymphocyte regulated gene 5c-like (Xlr5c-like) is a novel target of progesterone action in granulosa cells of periovulatory rat ovaries. Mol Cell Endocrinol. 2015;412:226-38 pubmed publisher
McCully M, Collins P, Hughes T, Thomas C, Billen J, O Donnell V, et al. Skin Metabolites Define a New Paradigm in the Localization of Skin Tropic Memory T Cells. J Immunol. 2015;195:96-104 pubmed publisher
Feng X, Li Z, Du Y, Fu H, Klein J, Cai H, et al. Downregulation of urea transporter UT-A1 activity by 14-3-3 protein. Am J Physiol Renal Physiol. 2015;309:F71-8 pubmed publisher
Basak S, Desai D, Rho E, Ramos R, Maurel P, Kim H. E-cadherin enhances neuregulin signaling and promotes Schwann cell myelination. Glia. 2015;63:1522-36 pubmed publisher
Sears P, Yin W, Ostrowski L. Continuous mucociliary transport by primary human airway epithelial cells in vitro. Am J Physiol Lung Cell Mol Physiol. 2015;309:L99-108 pubmed publisher
Janero D, Yaddanapudi S, Zvonok N, Subramanian K, Shukla V, Stahl E, et al. Molecular-interaction and signaling profiles of AM3677, a novel covalent agonist selective for the cannabinoid 1 receptor. ACS Chem Neurosci. 2015;6:1400-10 pubmed publisher
Munoz Abraham A, Judeeba S, Alkukhun A, Alfadda T, Patron Lozano R, Rodriguez Davalos M, et al. A new method to measure intestinal secretion using fluorescein isothiocyanate-inulin in small bowel of rats. J Surg Res. 2015;197:225-30 pubmed publisher
Lakk M, Denes V, Gabriel R. Pituitary Adenylate Cyclase-Activating Polypeptide Receptors Signal via Phospholipase C Pathway to Block Apoptosis in Newborn Rat Retina. Neurochem Res. 2015;40:1402-9 pubmed publisher
Carpi S, Fogli S, Romanini A, Pellegrino M, Adinolfi B, Podestà A, et al. AM251 induces apoptosis and G2/M cell cycle arrest in A375 human melanoma cells. Anticancer Drugs. 2015;26:754-62 pubmed publisher
Liao W, Huang N, Yu J, Jares A, Yang J, ZIEVE G, et al. Direct Conversion of Cord Blood CD34+ Cells Into Neural Stem Cells by OCT4. Stem Cells Transl Med. 2015;4:755-63 pubmed publisher
Mickle A, Shepherd A, Loo L, Mohapatra D. Induction of thermal and mechanical hypersensitivity by parathyroid hormone-related peptide through upregulation of TRPV1 function and trafficking. Pain. 2015;156:1620-36 pubmed publisher
Zhou L, Zhang J, Liu X, Zhou L. Co-Graft of Bone Marrow Stromal Cells and Schwann Cells Into Acellular Nerve Scaffold for Sciatic Nerve Regeneration in Rats. J Oral Maxillofac Surg. 2015;73:1651-60 pubmed publisher
Cernecka H, Kersten K, Maarsingh H, Elzinga C, de Jong I, Korstanje C, et al. β3-Adrenoceptor-mediated relaxation of rat and human urinary bladder: roles of BKCa channels and Rho kinase. Naunyn Schmiedebergs Arch Pharmacol. 2015;388:749-59 pubmed publisher
Zhang Y, Chen M, Zhou Y, Yi L, Gao Y, Ran L, et al. Resveratrol improves hepatic steatosis by inducing autophagy through the cAMP signaling pathway. Mol Nutr Food Res. 2015;59:1443-57 pubmed publisher
Prideaux M, Dallas S, Zhao N, Johnsrud E, Veno P, Guo D, et al. Parathyroid Hormone Induces Bone Cell Motility and Loss of Mature Osteocyte Phenotype through L-Calcium Channel Dependent and Independent Mechanisms. PLoS ONE. 2015;10:e0125731 pubmed publisher
Liu H, Angert M, Nishihara T, Shubayev I, Dolkas J, Shubayev V. Spinal Glia Division Contributes to Conditioning Lesion-Induced Axon Regeneration Into the Injured Spinal Cord: Potential Role of Cyclic AMP-Induced Tissue Inhibitor of Metalloproteinase-1. J Neuropathol Exp Neurol. 2015;74:500-11 pubmed publisher
Bernard L, Zhang H. MARK/Par1 Kinase Is Activated Downstream of NMDA Receptors through a PKA-Dependent Mechanism. PLoS ONE. 2015;10:e0124816 pubmed publisher
Zhang J, Tang H, Deng R, Wang N, Zhang Y, Wang Y, et al. Berberine Suppresses Adipocyte Differentiation via Decreasing CREB Transcriptional Activity. PLoS ONE. 2015;10:e0125667 pubmed publisher
Douris N, Stevanović D, Fisher F, Cisu T, Chee M, Nguyen N, et al. Central Fibroblast Growth Factor 21 Browns White Fat via Sympathetic Action in Male Mice. Endocrinology. 2015;156:2470-81 pubmed publisher
Jung A, Kim R, Kim H, Shrestha K, Jeon S, Cha K, et al. Nanoengineered Polystyrene Surfaces with Nanopore Array Pattern Alters Cytoskeleton Organization and Enhances Induction of Neural Differentiation of Human Adipose-Derived Stem Cells. Tissue Eng Part A. 2015;21:2115-24 pubmed publisher
Sprenger J, Perera R, Steinbrecher J, Lehnart S, Maier L, Hasenfuss G, et al. In vivo model with targeted cAMP biosensor reveals changes in receptor-microdomain communication in cardiac disease. Nat Commun. 2015;6:6965 pubmed publisher
Sayasith K, Sirois J. Molecular characterization of a disintegrin and metalloprotease-17 (ADAM17) in granulosa cells of bovine preovulatory follicles. Mol Cell Endocrinol. 2015;411:49-57 pubmed publisher
Sokolowska M, Chen L, Liu Y, Martinez Anton A, Qi H, Logun C, et al. Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages. J Immunol. 2015;194:5472-5487 pubmed publisher
Chung J, Huber T, Gödel M, Jarad G, Hartleben B, Kwoh C, et al. Albumin-associated free fatty acids induce macropinocytosis in podocytes. J Clin Invest. 2015;125:2307-16 pubmed publisher
Parnell E, Koschinski A, Zaccolo M, Cameron R, Baillie G, Baillie G, et al. Phosphorylation of ezrin on Thr567 is required for the synergistic activation of cell spreading by EPAC1 and protein kinase A in HEK293T cells. Biochim Biophys Acta. 2015;1853:1749-58 pubmed publisher
Laube M, Bossmann M, Thome U. Glucocorticoids Distinctively Modulate the CFTR Channel with Possible Implications in Lung Development and Transition into Extrauterine Life. PLoS ONE. 2015;10:e0124833 pubmed publisher
Aghababaei M, Hogg K, Perdu S, Robinson W, Beristain A. ADAM12-directed ectodomain shedding of E-cadherin potentiates trophoblast fusion. Cell Death Differ. 2015;22:1970-84 pubmed publisher
Bartesaghi L, Arnaud Gouttenoire E, Prunotto A, Médard J, Bergmann S, Chrast R. Sox4 participates in the modulation of Schwann cell myelination. Eur J Neurosci. 2015;42:1788-96 pubmed publisher
Ramírez D, Saba J, Carniglia L, Durand D, Lasaga M, Caruso C. Melanocortin 4 receptor activates ERK-cFos pathway to increase brain-derived neurotrophic factor expression in rat astrocytes and hypothalamus. Mol Cell Endocrinol. 2015;411:28-37 pubmed publisher
Hakim J, Esmaeili Rad M, Grahn P, Chen B, Knight A, Schmeichel A, et al. Positively Charged Oligo[Poly(Ethylene Glycol) Fumarate] Scaffold Implantation Results in a Permissive Lesion Environment after Spinal Cord Injury in Rat. Tissue Eng Part A. 2015;21:2099-114 pubmed publisher
Huang H, Liao D, Liang L, Song L, Zhao W. Genistein inhibits rotavirus replication and upregulates AQP4 expression in rotavirus-infected Caco-2 cells. Arch Virol. 2015;160:1421-33 pubmed publisher
McDonagh B, Volden S, Lystvet S, Singh G, Ese M, Ryan J, et al. Self-assembly and characterization of transferrin-gold nanoconstructs and their interaction with bio-interfaces. Nanoscale. 2015;7:8062-70 pubmed publisher
Wong P, Randall M, Roberts R. Sex differences in the role of NADPH oxidases in endothelium-dependent vasorelaxation in porcine isolated coronary arteries. Vascul Pharmacol. 2015;72:83-92 pubmed publisher
Kim P, Nakano H, Das P, Chen M, Rowe R, Chou S, et al. Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence. J Exp Med. 2015;212:633-48 pubmed publisher
Ho Y, Cheng J, Chiou L. Impairment of adenylyl cyclase-mediated glutamatergic synaptic plasticity in the periaqueductal grey in a rat model of neuropathic pain. J Physiol. 2015;593:2955-73 pubmed publisher
Li D, Hérault K, Zylbersztejn K, Lauterbach M, Guillon M, Oheim M, et al. Astrocyte VAMP3 vesicles undergo Ca2+ -independent cycling and modulate glutamate transporter trafficking. J Physiol. 2015;593:2807-32 pubmed publisher
Asraf H, Amsterdam A, Ben Menahem D. Modulation of the steroidogenic related activity according to the design of single-chain bovine FSH analogs. Gen Comp Endocrinol. 2015;216:171-81 pubmed publisher
Khankan R, Wanner I, Phelps P. Olfactory ensheathing cell-neurite alignment enhances neurite outgrowth in scar-like cultures. Exp Neurol. 2015;269:93-101 pubmed publisher
Daems C, Di Luoffo M, Paradis Ã, Tremblay J. MEF2 Cooperates With Forskolin/cAMP and GATA4 to Regulate Star Gene Expression in Mouse MA-10 Leydig Cells. Endocrinology. 2015;156:2693-703 pubmed publisher
Lee H, Lee H, Yun Y, Kim J, Ha Y, Yoon D, et al. Human Adipose Stem Cells Improve Mechanical Allodynia and Enhance Functional Recovery in a Rat Model of Neuropathic Pain. Tissue Eng Part A. 2015;21:2044-52 pubmed publisher
Robinson J, McDonald P. The orexin 1 receptor modulates kappa opioid receptor function via a JNK-dependent mechanism. Cell Signal. 2015;27:1449-56 pubmed publisher
Macêdo C, Vasconcelos L, Correia A, Martins I, Lira D, Santos B, et al. Mechanisms underlying the relaxant effect of Galetin 3,6- dimethyl ether, from Piptadenia stipulacea (Benth.) Ducke, on guinea-pig trachea. Z Naturforsch C J Biosci. 2014;69:434-42 pubmed publisher
Kappe C, Fransson L, Wolbert P, Ortsäter H. Glucocorticoids suppress GLP-1 secretion: possible contribution to their diabetogenic effects. Clin Sci (Lond). 2015;129:405-14 pubmed publisher
Wang Y, Wang W, Wo Y, Gui T, Zhu H, Mo X, et al. Orientated Guidance of Peripheral Nerve Regeneration Using Conduits with a Microtube Array Sheet (MTAS). ACS Appl Mater Interfaces. 2015;7:8437-50 pubmed publisher
Vedel L, Bräuner Osborne H, Mathiesen J. A cAMP Biosensor-Based High-Throughput Screening Assay for Identification of Gs-Coupled GPCR Ligands and Phosphodiesterase Inhibitors. J Biomol Screen. 2015;20:849-57 pubmed publisher
Blazer L, Storaska A, Jutkiewicz E, Turner E, Calcagno M, Wade S, et al. Selectivity and anti-Parkinson's potential of thiadiazolidinone RGS4 inhibitors. ACS Chem Neurosci. 2015;6:911-9 pubmed publisher
Sinha C, Ren A, Arora K, Moon C, Yarlagadda S, Woodrooffe K, et al. PKA and actin play critical roles as downstream effectors in MRP4-mediated regulation of fibroblast migration. Cell Signal. 2015;27:1345-55 pubmed publisher
Guo T, Gamil A, Koenig M, Evensen Ã. Sequence analysis and identification of new isoform of EP4 receptors in different atlantic salmon tissues (Salmo salar L.) and its role in PGE2 induced immunomodulation in vitro. PLoS ONE. 2015;10:e0120483 pubmed publisher
Nussbaum C, Bannenberg S, Keul P, Gräler M, Gonçalves de Albuquerque C, Korhonen H, et al. Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin. Nat Commun. 2015;6:6416 pubmed publisher
Rajan S, Dickson L, Mathew E, Orr C, Ellenbroek J, Philipson L, et al. Chronic hyperglycemia downregulates GLP-1 receptor signaling in pancreatic β-cells via protein kinase A. Mol Metab. 2015;4:265-76 pubmed publisher
Belgacem Y, Borodinsky L. Inversion of Sonic hedgehog action on its canonical pathway by electrical activity. Proc Natl Acad Sci U S A. 2015;112:4140-5 pubmed publisher
Henke D, Rupp S, Gaschen V, Stoffel M, Frey J, Vandevelde M, et al. Listeria monocytogenes spreads within the brain by actin-based intra-axonal migration. Infect Immun. 2015;83:2409-19 pubmed publisher
Guan P, Yu X, Guo J, Wang Y, Wang T, Li J, et al. By activating matrix metalloproteinase-7, shear stress promotes chondrosarcoma cell motility, invasion and lung colonization. Oncotarget. 2015;6:9140-59 pubmed
Schäfer S, Han J, Pena M, Von Bohlen Und Halbach O, Peters J, Gage F. The Wnt adaptor protein ATP6AP2 regulates multiple stages of adult hippocampal neurogenesis. J Neurosci. 2015;35:4983-98 pubmed publisher
Siddappa D, Beaulieu Ã, Gévry N, Roux P, Bordignon V, Duggavathi R. Effect of the transient pharmacological inhibition of Mapk3/1 pathway on ovulation in mice. PLoS ONE. 2015;10:e0119387 pubmed publisher
Li C, Lu Q, Huang P, Fu T, Li C, Guo L, et al. Activity-dependent downregulation of M-Type (Kv7) K⁺ channels surface expression requires the activation of iGluRs/Ca²⁺/PKC signaling pathway in hippocampal neuron. Neuropharmacology. 2015;95:154-67 pubmed publisher
Chernov A, Dolkas J, Hoang K, Angert M, Srikrishna G, Vogl T, et al. The calcium-binding proteins S100A8 and S100A9 initiate the early inflammatory program in injured peripheral nerves. J Biol Chem. 2015;290:11771-84 pubmed publisher
Tang L, Peng M, Liu L, Chang W, Binder H, Cheng S. Calcium-sensing receptor stimulates Cl(-)- and SCFA-dependent but inhibits cAMP-dependent HCO3(-) secretion in colon. Am J Physiol Gastrointest Liver Physiol. 2015;308:G874-83 pubmed publisher
Liu N, Zhang D, Zhu M, Luo S, Liu T. Minocycline inhibits hyperpolarization-activated currents in rat substantia gelatinosa neurons. Neuropharmacology. 2015;95:110-20 pubmed publisher
Xia J, Fang M, Wu X, Yang Y, Yu L, Xu H, et al. A2b adenosine signaling represses CIITA transcription via an epigenetic mechanism in vascular smooth muscle cells. Biochim Biophys Acta. 2015;1849:665-76 pubmed publisher
Parameswaran S, DRAVID S, Teotia P, Krishnamoorthy R, Qiu F, Toris C, et al. Continuous non-cell autonomous reprogramming to generate retinal ganglion cells for glaucomatous neuropathy. Stem Cells. 2015;33:1743-58 pubmed publisher
Hummel J, Kammerer U, Müller N, Avota E, Schneider Schaulies S. Human endogenous retrovirus envelope proteins target dendritic cells to suppress T-cell activation. Eur J Immunol. 2015;45:1748-59 pubmed publisher
Armaiz Pena G, Gonzalez Villasana V, Nagaraja A, Rodriguez Aguayo C, Sadaoui N, Stone R, et al. Adrenergic regulation of monocyte chemotactic protein 1 leads to enhanced macrophage recruitment and ovarian carcinoma growth. Oncotarget. 2015;6:4266-73 pubmed
Yao Y, Cui X, Al Ramahi I, Sun X, Li B, Hou J, et al. A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity. elife. 2015;4: pubmed publisher
Tsukamoto Yamauchi N, Terasaka T, Iwasaki Y, Otsuka F. Interaction of pituitary hormones and expression of clock genes modulated by bone morphogenetic protein-4 and melatonin. Biochem Biophys Res Commun. 2015;459:172-7 pubmed publisher
Mangmool S, Hemplueksa P, Parichatikanond W, Chattipakorn N. Epac is required for GLP-1R-mediated inhibition of oxidative stress and apoptosis in cardiomyocytes. Mol Endocrinol. 2015;29:583-96 pubmed publisher
Souza G, Simas A, Bastos Pereira A, Frois G, Ribas J, Verdan M, et al. Antinociceptive activity of the ethanolic extract, fractions, and aggregatin D isolated from Sinningia aggregata tubers. PLoS ONE. 2015;10:e0117501 pubmed publisher
Egashira Y, Takase M, Takamori S. Monitoring of vacuolar-type H+ ATPase-mediated proton influx into synaptic vesicles. J Neurosci. 2015;35:3701-10 pubmed publisher
Nguyen T, Yong H, Chollangi T, Borg A, Brennecke S, Murthi P. Placental vitamin D receptor expression is decreased in human idiopathic fetal growth restriction. J Mol Med (Berl). 2015;93:795-805 pubmed publisher
Trouvé P, Kerbiriou M, Teng L, Benz N, Taiya M, le Hir S, et al. G551D-CFTR needs more bound actin than wild-type CFTR to maintain its presence in plasma membranes. Cell Biol Int. 2015;39:978-85 pubmed publisher
Jóźwiak Bębenista M, Kowalczyk E, Nowak J. The cyclic AMP effects and neuroprotective activities of PACAP and VIP in cultured astrocytes and neurons exposed to oxygen-glucose deprivation. Pharmacol Rep. 2015;67:332-8 pubmed publisher
Bacallao K, Monje P. Requirement of cAMP signaling for Schwann cell differentiation restricts the onset of myelination. PLoS ONE. 2015;10:e0116948 pubmed publisher
Wattanachanya L, Wang L, Millard S, Lu W, O Carroll D, Hsiao E, et al. Assessing the osteoblast transcriptome in a model of enhanced bone formation due to constitutive Gs-G protein signaling in osteoblasts. Exp Cell Res. 2015;333:289-302 pubmed publisher
Kasahara K, Hashimoto S, Hattori T, Kawasaki K, Tsujita R, Nakazono O, et al. The effects of AP521, a novel anxiolytic drug, in three anxiety models and on serotonergic neural transmission in rats. J Pharmacol Sci. 2015;127:109-16 pubmed publisher
Peng J, Han P, Xin H, Ji S, Gao K, An X, et al. Molecular characterization and hormonal regulation of tissue inhibitor of metalloproteinase 1 in goat ovarian granulosa cells. Domest Anim Endocrinol. 2015;52:1-10 pubmed publisher
Ren Q, Wang Y, Gong W, Zhou Q, Xu L, Zhang Z. Escitalopram Ameliorates Forskolin-Induced Tau Hyperphosphorylation in HEK239/tau441 Cells. J Mol Neurosci. 2015;56:500-8 pubmed publisher
Wang L, Burmeister B, Johnson K, Baillie G, Karginov A, Skidgel R, et al. UCR1C is a novel activator of phosphodiesterase 4 (PDE4) long isoforms and attenuates cardiomyocyte hypertrophy. Cell Signal. 2015;27:908-22 pubmed publisher
Byrne A, Elliott C, Hoffmann R, Baillie G. The activity of cAMP-phosphodiesterase 4D7 (PDE4D7) is regulated by protein kinase A-dependent phosphorylation within its unique N-terminus. FEBS Lett. 2015;589:750-5 pubmed publisher
Mulumba M, Granata R, Marleau S, Ong H. QRFP-43 inhibits lipolysis by preventing ligand-induced complex formation between perilipin A, caveolin-1, the catalytic subunit of protein kinase and hormone-sensitive lipase in 3T3-L1 adipocytes. Biochim Biophys Acta. 2015;1851:657-66 pubmed publisher
Evans R, Herin G, Hawes S, Blackwell K. Calcium-dependent inactivation of calcium channels in the medial striatum increases at eye opening. J Neurophysiol. 2015;113:2979-86 pubmed publisher
Fritz A, Adil M, Mao S, Schaffer D. cAMP and EPAC Signaling Functionally Replace OCT4 During Induced Pluripotent Stem Cell Reprogramming. Mol Ther. 2015;23:952-963 pubmed publisher
Zhong M, Song W, Xu Y, Ye Y, Feng L. Paeoniflorin ameliorates ischemic neuronal damage in vitro via adenosine A1 receptor-mediated transactivation of epidermal growth factor receptor. Acta Pharmacol Sin. 2015;36:298-310 pubmed publisher
Ishikawa K, Tsunekawa S, Ikeniwa M, Izumoto T, Iida A, Ogata H, et al. Long-term pancreatic beta cell exposure to high levels of glucose but not palmitate induces DNA methylation within the insulin gene promoter and represses transcriptional activity. PLoS ONE. 2015;10:e0115350 pubmed publisher
Baron L, Gombault A, Fanny M, Villeret B, Savigny F, Guillou N, et al. The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine. Cell Death Dis. 2015;6:e1629 pubmed publisher
Zhang F, Qi Y, Zhou K, Zhang G, Linask K, Xu H. The cAMP phosphodiesterase Prune localizes to the mitochondrial matrix and promotes mtDNA replication by stabilizing TFAM. EMBO Rep. 2015;16:520-7 pubmed publisher
Miyauchi T, Yamamoto H, Abe Y, Yoshida G, Rojek A, Sohara E, et al. Dynamic subcellular localization of aquaporin-7 in white adipocytes. FEBS Lett. 2015;589:608-14 pubmed publisher
Park Y, Mueller B, McGrady N, Ma H, Yorio T. AMPA receptor desensitization is the determinant of AMPA receptor mediated excitotoxicity in purified retinal ganglion cells. Exp Eye Res. 2015;132:136-50 pubmed publisher
Sun F, Yang X, Lv H, Tang Y, An S, Ding X, et al. β2-Adrenoreceptor-Mediated Proliferation Inhibition of Embryonic Pluripotent Stem Cells. J Cell Physiol. 2015;230:2640-6 pubmed publisher
Lee J, Graham M, Collins T, Lee J, Hong S, Mcnicol A, et al. Reversible lineage-specific priming of human embryonic stem cells can be exploited to optimize the yield of differentiated cells. Stem Cells. 2015;33:1142-52 pubmed publisher
Wang X, Docanto M, Sasano H, Lo C, Simpson E, Brown K. Prostaglandin E2 inhibits p53 in human breast adipose stromal cells: a novel mechanism for the regulation of aromatase in obesity and breast cancer. Cancer Res. 2015;75:645-55 pubmed publisher
Ang Z, Er J, Ding J. The short-chain fatty acid receptor GPR43 is transcriptionally regulated by XBP1 in human monocytes. Sci Rep. 2015;5:8134 pubmed publisher
Kalayou S, Ndossi D, Frizzell C, Groseth P, Connolly L, Sørlie M, et al. An investigation of the endocrine disrupting potential of enniatin B using in vitro bioassays. Toxicol Lett. 2015;233:84-94 pubmed publisher
Sadegh M, Ekman M, Krawczyk K, Svensson D, Göransson O, Dahan D, et al. Detrusor induction of miR-132/212 following bladder outlet obstruction: association with MeCP2 repression and cell viability. PLoS ONE. 2015;10:e0116784 pubmed publisher
Li Y, Zheng R, Wang R, Lu X, Zhu C, Lin H, et al. Involvement of nephrin in human placental trophoblast syncytialization. Reproduction. 2015;149:339-46 pubmed publisher
Razavi S, Zarkesh Esfahani H, Morshed M, Vaezifar S, Karbasi S, Golozar M. Nanobiocomposite of poly(lactide-co-glycolide)/chitosan electrospun scaffold can promote proliferation and transdifferentiation of Schwann-like cells from human adipose-derived stem cells. J Biomed Mater Res A. 2015;103:2628-34 pubmed publisher
Huang Y, Zheng L, Yang H, Chen J, Wang Y, Li H, et al. Measuring the dynamics of cyclic adenosine monophosphate level in living cells induced by low-level laser irradiation using bioluminescence resonance energy transfer. J Biomed Opt. 2015;20:051029 pubmed publisher
Rajgopal A, Rebhun J, Burns C, Scholten J, Balles J, Fast D. Immunomodulatory effects of Lippia sidoides extract: induction of IL-10 through cAMP and p38 MAPK-dependent mechanisms. J Med Food. 2015;18:370-7 pubmed publisher
Yui S, Fujita N, Chung C, Morita M, Nishimura R. Olfactory ensheathing cells (OECs) degrade neurocan in injured spinal cord by secreting matrix metalloproteinase-2 in a rat contusion model. Jpn J Vet Res. 2014;62:151-62 pubmed
Song W, Jin X. Cyclic AMP inhibits neuromuscular junction maturation mediated by intracellular Ca2+. Neurosci Lett. 2015;589:104-9 pubmed publisher
Terra S, Cardoso J, Félix R, Martins L, Souza D, Guma F, et al. STC1 interference on calcitonin family of receptors signaling during osteoblastogenesis via adenylate cyclase inhibition. Mol Cell Endocrinol. 2015;403:78-87 pubmed publisher
Zhu G, Liu Y, Wang Y, Bi X, Baudry M. Different patterns of electrical activity lead to long-term potentiation by activating different intracellular pathways. J Neurosci. 2015;35:621-33 pubmed publisher
Huang L, Quan X, Liu Z, Ma T, Wu Y, Ge J, et al. c-Jun gene-modified Schwann cells: upregulating multiple neurotrophic factors and promoting neurite outgrowth. Tissue Eng Part A. 2015;21:1409-21 pubmed publisher
Sun K, Zhang Y, Bogdanov M, Wu H, Song A, Li J, et al. Elevated adenosine signaling via adenosine A2B receptor induces normal and sickle erythrocyte sphingosine kinase 1 activity. Blood. 2015;125:1643-52 pubmed publisher
Gnavi S, Fornasari B, Tonda Turo C, Ciardelli G, Zanetti M, Geuna S, et al. The influence of electrospun fibre size on Schwann cell behaviour and axonal outgrowth. Mater Sci Eng C Mater Biol Appl. 2015;48:620-31 pubmed publisher
Labeur M, Wölfel B, Stalla J, Stalla G. TMEFF2 is an endogenous inhibitor of the CRH signal transduction pathway. J Mol Endocrinol. 2015;54:51-63 pubmed publisher
Jaeger C, Sandu C, Malan A, Mellac K, Hicks D, Felder Schmittbuhl M. Circadian organization of the rodent retina involves strongly coupled, layer-specific oscillators. FASEB J. 2015;29:1493-504 pubmed publisher
Long P, Tighe S, Driscoll H, Fortner K, Viapiano M, Jaworski D. Acetate supplementation as a means of inducing glioblastoma stem-like cell growth arrest. J Cell Physiol. 2015;230:1929-43 pubmed publisher
Siwetz M, Sundl M, Kolb D, Hiden U, Herse F, Huppertz B, et al. Placental fractalkine mediates adhesion of THP-1 monocytes to villous trophoblast. Histochem Cell Biol. 2015;143:565-74 pubmed publisher
Wang Y, Yang C, Chen Y, Gong C, Chen Y, Kuo Y, et al. Inhibitory effects of imperatorin on voltage-gated K(+) channels and ATP-sensitive K(+) channels. Pharmacol Rep. 2015;67:134-9 pubmed publisher
Cheng J, Chang H, Fang L, Sun Y, Leung P. TGF-β1 up-regulates connexin43 expression: a potential mechanism for human trophoblast cell differentiation. J Cell Physiol. 2015;230:1558-66 pubmed publisher
Rodgers J, Robinson A, Rosler E, Lariosa Willingham K, Persons R, Dugas J, et al. IL-17A activates ERK1/2 and enhances differentiation of oligodendrocyte progenitor cells. Glia. 2015;63:768-79 pubmed publisher
Yao L, Li Y, Knapp J, Smith P. Exploration of molecular pathways mediating electric field-directed Schwann cell migration by RNA-seq. J Cell Physiol. 2015;230:1515-24 pubmed publisher
Bon H, Wadhwa K, Schreiner A, Osborne M, Carroll T, Ramos Montoya A, et al. Salt-inducible kinase 2 regulates mitotic progression and transcription in prostate cancer. Mol Cancer Res. 2015;13:620-635 pubmed publisher
Kawaratani Y, Matsuoka T, Hirata Y, Fukata N, Nagaoka Y, Uesato S. Influence of the carbamate fungicide benomyl on the gene expression and activity of aromatase in the human breast carcinoma cell line MCF-7. Environ Toxicol Pharmacol. 2015;39:292-9 pubmed publisher
Brust T, Hayes M, Roman D, Burris K, Watts V. Bias analyses of preclinical and clinical D2 dopamine ligands: studies with immediate and complex signaling pathways. J Pharmacol Exp Ther. 2015;352:480-93 pubmed publisher
Noh K, Maze I, Zhao D, Xiang B, Wenderski W, Lewis P, et al. ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons. Proc Natl Acad Sci U S A. 2015;112:6820-7 pubmed publisher
Fujiwara S, Hoshikawa S, Ueno T, Hirata M, Saito T, Ikeda T, et al. SOX10 transactivates S100B to suppress Schwann cell proliferation and to promote myelination. PLoS ONE. 2014;9:e115400 pubmed publisher
Spies C, Hoff P, Mazuch J, Gaber T, Maier B, Strehl C, et al. Circadian rhythms of cellular immunity in rheumatoid arthritis: a hypothesis-generating study. Clin Exp Rheumatol. 2015;33:34-43 pubmed
Medani M, Collins D, Mohan H, Walsh E, Winter D, Baird A. Prostaglandin D2 regulates human colonic ion transport via the DP1 receptor. Life Sci. 2015;122:87-91 pubmed publisher
Knapman A, Santiago M, Connor M. A6V polymorphism of the human μ-opioid receptor decreases signalling of morphine and endogenous opioids in vitro. Br J Pharmacol. 2015;172:2258-72 pubmed publisher
Handorf A, Chamberlain C, Li W. Endogenously produced Indian Hedgehog regulates TGFβ-driven chondrogenesis of human bone marrow stromal/stem cells. Stem Cells Dev. 2015;24:995-1007 pubmed publisher
Mack S, Cook D, Dhurjati P, Butchbach M. Systems biology investigation of cAMP modulation to increase SMN levels for the treatment of spinal muscular atrophy. PLoS ONE. 2014;9:e115473 pubmed publisher
Kobalava Z, Villevalde S, Kotovskaya Y, Hinrichsen H, Petersen Sylla M, Zaehringer A, et al. Pharmacokinetics of serelaxin in patients with hepatic impairment: a single-dose, open-label, parallel group study. Br J Clin Pharmacol. 2015;79:937-45 pubmed publisher
Bergeron F, Nadeau G, Viger R. GATA4 knockdown in MA-10 Leydig cells identifies multiple target genes in the steroidogenic pathway. Reproduction. 2015;149:245-57 pubmed publisher
Marquardt L, Sakiyama Elbert S. GDNF preconditioning can overcome Schwann cell phenotypic memory. Exp Neurol. 2015;265:1-7 pubmed publisher
Kriisa M, Sinijärv H, Vaasa A, Enkvist E, Kostenko S, Moens U, et al. Inhibition of CREB phosphorylation by conjugates of adenosine analogues and arginine-rich peptides, inhibitors of PKA catalytic subunit. Chembiochem. 2015;16:312-9 pubmed publisher
Vandame P, Spriet C, Trinel D, Gelaude A, Caillau K, Bompard C, et al. The spatio-temporal dynamics of PKA activity profile during mitosis and its correlation to chromosome segregation. Cell Cycle. 2014;13:3232-40 pubmed publisher
Tsukamoto M, Sango K, Niimi N, Yanagisawa H, Watabe K, Utsunomiya K. Upregulation of galectin-3 in immortalized Schwann cells IFRS1 under diabetic conditions. Neurosci Res. 2015;92:80-5 pubmed publisher
Wei Y, Li K, Wang N, Cai G, Zhang T, Lin Y, et al. Activation of endogenous anti-inflammatory mediator cyclic AMP attenuates acute pyelonephritis in mice induced by uropathogenic Escherichia coli. Am J Pathol. 2015;185:472-84 pubmed publisher
Pavan B, Capuzzo A, Forlani G. Quercetin and quercetin-3-O-glucoside interact with different components of the cAMP signaling cascade in human retinal pigment epithelial cells. Life Sci. 2015;121:166-73 pubmed publisher
Lu J, Reese J, Zhou Y, Hirsch E. Progesterone-induced activation of membrane-bound progesterone receptors in murine macrophage cells. J Endocrinol. 2015;224:183-94 pubmed publisher
Lee J, Lee J, Shapovalova Z, Fiebig Comyn A, Mitchell R, Laronde S, et al. Somatic transcriptome priming gates lineage-specific differentiation potential of human-induced pluripotent stem cell states. Nat Commun. 2014;5:5605 pubmed publisher
Terashima M, Amano M, Onodera T, Nishimura S, Iwasaki N. Quantitative glycomics monitoring of induced pluripotent- and embryonic stem cells during neuronal differentiation. Stem Cell Res. 2014;13:454-64 pubmed publisher
St John H, Meyer M, Benkusky N, Carlson A, Prideaux M, Bonewald L, et al. The parathyroid hormone-regulated transcriptome in osteocytes: parallel actions with 1,25-dihydroxyvitamin D3 to oppose gene expression changes during differentiation and to promote mature cell function. Bone. 2015;72:81-91 pubmed publisher
Cook D, Nuro E, Jones E, Altimimi H, Farmer W, Gandin V, et al. FXR1P limits long-term memory, long-lasting synaptic potentiation, and de novo GluA2 translation. Cell Rep. 2014;9:1402-1416 pubmed publisher
Georgiou M, Golding J, Loughlin A, Kingham P, Phillips J. Engineered neural tissue with aligned, differentiated adipose-derived stem cells promotes peripheral nerve regeneration across a critical sized defect in rat sciatic nerve. Biomaterials. 2015;37:242-51 pubmed publisher
Mohan S, Narumiya S, Doré S. Neuroprotective role of prostaglandin PGE2 EP2 receptor in hemin-mediated toxicity. Neurotoxicology. 2015;46:53-9 pubmed publisher
Jiang Y, Yu B, Wang X, Sui Y, Zhang Y, Yang S, et al. Stimulation effect of wide type CFTR chloride channel by the naturally occurring flavonoid tangeretin. Fitoterapia. 2014;99:284-91 pubmed publisher
Frey E, Valakh V, Karney Grobe S, Shi Y, Milbrandt J, DiAntonio A. An in vitro assay to study induction of the regenerative state in sensory neurons. Exp Neurol. 2015;263:350-63 pubmed publisher
Weber Boyvat M, Kentala H, Lilja J, Vihervaara T, Hanninen R, Zhou Y, et al. OSBP-related protein 3 (ORP3) coupling with VAMP-associated protein A regulates R-Ras activity. Exp Cell Res. 2015;331:278-91 pubmed publisher
Corritore E, Dugnani E, Pasquale V, Misawa R, Witkowski P, Lei J, et al. β-Cell differentiation of human pancreatic duct-derived cells after in vitro expansion. Cell Reprogram. 2014;16:456-66 pubmed publisher
Liu J, Deng G, Zhang J, Wang Y, Xia X, Luo X, et al. The effect of chronic stress on anti-angiogenesis of sunitinib in colorectal cancer models. Psychoneuroendocrinology. 2015;52:130-42 pubmed publisher
Lee S, AMICI S, Tavori H, Zeng W, Freeland S, Fazio S, et al. PMP22 is critical for actin-mediated cellular functions and for establishing lipid rafts. J Neurosci. 2014;34:16140-52 pubmed publisher
Vega A, Martinot E, Baptissart M, de Haze A, Saru J, Baron S, et al. Identification of the link between the hypothalamo-pituitary axis and the testicular orphan nuclear receptor NR0B2 in adult male mice. Endocrinology. 2015;156:660-9 pubmed publisher
Sahu Osen A, Montero Moran G, Schittmayer M, Fritz K, Dinh A, Chang Y, et al. CGI-58/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localization. J Lipid Res. 2015;56:109-21 pubmed publisher
Li H, Zhong X, Chau K, Santistevan N, Guo W, Kong G, et al. Cell cycle-linked MeCP2 phosphorylation modulates adult neurogenesis involving the Notch signalling pathway. Nat Commun. 2014;5:5601 pubmed publisher
Li Z, Liu X, Liu Y, Xue Y, Wang P, Liu L. Role of cAMP-dependent protein kinase A activity in low-dose endothelial monocyte-activating polypeptide-II-induced opening of blood-tumor barrier. J Mol Neurosci. 2015;56:60-9 pubmed publisher
Lee H, Ha H, Lee J, Park S, Jeong S, Shin H. The Leaves of Broussonetia kazinoki Siebold Inhibit Atopic Dermatitis-Like Response on Mite Allergen-Treated Nc/Nga Mice. Biomol Ther (Seoul). 2014;22:438-44 pubmed publisher
Hutchison M, White P. Prostacyclin regulates bone growth via the Epac/Rap1 pathway. Endocrinology. 2015;156:499-510 pubmed publisher
Paz J, Park S, Phillips N, Matsumura S, Tsai W, Kasper L, et al. Combinatorial regulation of a signal-dependent activator by phosphorylation and acetylation. Proc Natl Acad Sci U S A. 2014;111:17116-21 pubmed publisher
Cho J, Zhang X, Miller G, Lencer W, Nery F. 4-Phenylbutyrate attenuates the ER stress response and cyclic AMP accumulation in DYT1 dystonia cell models. PLoS ONE. 2014;9:e110086 pubmed publisher
Li A, Zhao L, Zhou T, Zhang M, Qin X. Exendin-4 promotes endothelial barrier enhancement via PKA- and Epac1-dependent Rac1 activation. Am J Physiol Cell Physiol. 2015;308:C164-75 pubmed publisher
Xiao Y, Wang S. Differentiation of Schwann‑like cells from human umbilical cord blood mesenchymal stem cells in vitro. Mol Med Rep. 2015;11:1146-52 pubmed publisher
Apone F, Ruggiero A, Tortora A, Tito A, Grimaldi M, Arciello S, et al. Targeting the diuretic hormone receptor to control the cotton leafworm, Spodoptera littoralis. J Insect Sci. 2014;14:87 pubmed publisher
Wen X, Wang Y, Guo Z, Meng H, Huang J, Zhang L, et al. Cauda equina-derived extracellular matrix for fabrication of nanostructured hybrid scaffolds applied to neural tissue engineering. Tissue Eng Part A. 2015;21:1095-105 pubmed publisher
Berghold V, Gauster M, Hemmings D, Moser G, Kremshofer J, Siwetz M, et al. Phospholipid scramblase 1 (PLSCR1) in villous trophoblast of the human placenta. Histochem Cell Biol. 2015;143:381-96 pubmed publisher
Pajtler K, Mahlow E, Odersky A, Lindner S, Stephan H, Bendix I, et al. Neuroblastoma in dialog with its stroma: NTRK1 is a regulator of cellular cross-talk with Schwann cells. Oncotarget. 2014;5:11180-92 pubmed
De Stefano D, Villella V, Esposito S, Tosco A, Sepe A, de Gregorio F, et al. Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation. Autophagy. 2014;10:2053-74 pubmed publisher
Honsho K, Hirose M, Hatori M, Yasmin L, Izu H, Matoba S, et al. Naïve-like conversion enhances the difference in innate in vitro differentiation capacity between rabbit ES cells and iPS cells. J Reprod Dev. 2015;61:13-9 pubmed publisher
Munari F, Fassan M, Capitani N, Codolo G, Vila Caballer M, Pizzi M, et al. Cytokine BAFF released by Helicobacter pylori-infected macrophages triggers the Th17 response in human chronic gastritis. J Immunol. 2014;193:5584-94 pubmed publisher
Sayasith K, Sirois J, Lussier J. Expression and regulation of regulator of G-protein signaling protein-2 (RGS2) in equine and bovine follicles prior to ovulation: molecular characterization of RGS2 transactivation in bovine granulosa cells. Biol Reprod. 2014;91:139 pubmed publisher
Lamas N, Johnson Kerner B, Roybon L, Kim Y, Garcia Diaz A, Wichterle H, et al. Neurotrophic requirements of human motor neurons defined using amplified and purified stem cell-derived cultures. PLoS ONE. 2014;9:e110324 pubmed publisher
Danka E, Hunstad D. Cathelicidin augments epithelial receptivity and pathogenesis in experimental Escherichia coli cystitis. J Infect Dis. 2015;211:1164-73 pubmed publisher
Fujii H, Tamamori Adachi M, Uchida K, Susa T, Nakakura T, Hagiwara H, et al. Marked cortisol production by intracrine ACTH in GIP-treated cultured adrenal cells in which the GIP receptor was exogenously introduced. PLoS ONE. 2014;9:e110543 pubmed publisher
Goulart C, Jürgensen S, Souto A, Oliveira J, de Lima S, Tonda Turo C, et al. A combination of Schwann-cell grafts and aerobic exercise enhances sciatic nerve regeneration. PLoS ONE. 2014;9:e110090 pubmed publisher
Latif R, Ali M, Ma R, David M, Morshed S, Ohlmeyer M, et al. New small molecule agonists to the thyrotropin receptor. Thyroid. 2015;25:51-62 pubmed publisher
Robitaille C, Rivest P, Sanderson J. Antiandrogenic mechanisms of pesticides in human LNCaP prostate and H295R adrenocortical carcinoma cells. Toxicol Sci. 2015;143:126-35 pubmed publisher
Button R, Lin F, Ercolano E, Vincent J, Hu B, Hanemann C, et al. Artesunate induces necrotic cell death in schwannoma cells. Cell Death Dis. 2014;5:e1466 pubmed publisher
Fediuk J, Sikarwar A, Lizotte P, Hinton M, Nolette N, Dakshinamurti S. Hypoxia increases pulmonary arterial thromboxane receptor internalization independent of receptor sensitization. Pulm Pharmacol Ther. 2015;30:1-10 pubmed publisher
Bajracharya P, Lu H, Pietrantonio P. The red imported fire ant (Solenopsis invicta Buren) kept Y not F: predicted sNPY endogenous ligands deorphanize the short NPF (sNPF) receptor. PLoS ONE. 2014;9:e109590 pubmed publisher
Mueller B, Park Y, Ma H, Dibas A, Ellis D, Clark A, et al. Sigma-1 receptor stimulation protects retinal ganglion cells from ischemia-like insult through the activation of extracellular-signal-regulated kinases 1/2. Exp Eye Res. 2014;128:156-69 pubmed publisher
Yokoyama K, Ikeya M, Umeda K, Oda H, Nodomi S, Nasu A, et al. Enhanced chondrogenesis of induced pluripotent stem cells from patients with neonatal-onset multisystem inflammatory disease occurs via the caspase 1-independent cAMP/protein kinase A/CREB pathway. Arthritis Rheumatol. 2015;67:302-14 pubmed publisher
Copsel S, Bruzzone A, May M, Beyrath J, Wargon V, Cany J, et al. Multidrug resistance protein 4/ ATP binding cassette transporter 4: a new potential therapeutic target for acute myeloid leukemia. Oncotarget. 2014;5:9308-21 pubmed
Omar B, Sörhede Winzell M, Ahrén B. Conditional glucagon receptor overexpression has multi-faceted consequences for beta-cell function. Metabolism. 2014;63:1568-76 pubmed publisher
Lee J, Schmidt C. Amine-functionalized polypyrrole: Inherently cell adhesive conducting polymer. J Biomed Mater Res A. 2015;103:2126-32 pubmed publisher
Min C, Zheng M, Zhang X, Guo S, Kwon K, Shin C, et al. N-linked Glycosylation on the N-terminus of the dopamine D2 and D3 receptors determines receptor association with specific microdomains in the plasma membrane. Biochim Biophys Acta. 2015;1853:41-51 pubmed publisher
Eby J, Gray M, Hewlett E. Cyclic AMP-mediated suppression of neutrophil extracellular trap formation and apoptosis by the Bordetella pertussis adenylate cyclase toxin. Infect Immun. 2014;82:5256-69 pubmed publisher
Broadbent S, Ramjeesingh M, Bear C, Argent B, Linsdell P, Gray M. The cystic fibrosis transmembrane conductance regulator is an extracellular chloride sensor. Pflugers Arch. 2015;467:1783-94 pubmed publisher
Grove M, Brophy P. FAK is required for Schwann cell spreading on immature basal lamina to coordinate the radial sorting of peripheral axons with myelination. J Neurosci. 2014;34:13422-34 pubmed publisher
Mano H, Ishimoto T, Okada T, Toyooka N, Mori H. Discovery of novel adenylyl cyclase inhibitor by cell-based screening. Biol Pharm Bull. 2014;37:1689-93 pubmed
Fernández Dueñas V, Gómez Soler M, López Cano M, Taura J, Ledent C, Watanabe M, et al. Uncovering caffeine's adenosine A2A receptor inverse agonism in experimental parkinsonism. ACS Chem Biol. 2014;9:2496-501 pubmed publisher
Kim S, Lee Y, Baik J, Han J, Lee C, Heo K, et al. Baicalein inhibits agonist- and tumor cell-induced platelet aggregation while suppressing pulmonary tumor metastasis via cAMP-mediated VASP phosphorylation along with impaired MAPKs and PI3K-Akt activation. Biochem Pharmacol. 2014;92:251-65 pubmed publisher
Wong P, Garle M, Alexander S, Randall M, Roberts R. A role for the sodium pump in H2O2-induced vasorelaxation in porcine isolated coronary arteries. Pharmacol Res. 2014;90:25-35 pubmed publisher
Vajda F, Jordi N, Dalkara D, Joly S, Christ F, Tews B, et al. Cell type-specific Nogo-A gene ablation promotes axonal regeneration in the injured adult optic nerve. Cell Death Differ. 2015;22:323-35 pubmed publisher
Smith M, Sanchez Laorden B, O Brien K, Brunton H, Ferguson J, Young H, et al. The immune microenvironment confers resistance to MAPK pathway inhibitors through macrophage-derived TNFα. Cancer Discov. 2014;4:1214-1229 pubmed publisher
Pooya S, Liu X, Kumar V, Anderson J, Imai F, Zhang W, et al. The tumour suppressor LKB1 regulates myelination through mitochondrial metabolism. Nat Commun. 2014;5:4993 pubmed publisher
Kong X, Yan D, Sun J, Wu X, Mulder H, Hua X, et al. Glucagon-like peptide 1 stimulates insulin secretion via inhibiting RhoA/ROCK signaling and disassembling glucotoxicity-induced stress fibers. Endocrinology. 2014;155:4676-85 pubmed publisher
Zhang J, Liu Z, Chen H, Duan Z, Zhang L, Chen L, et al. Synergic effects of EPI-NCSCs and OECs on the donor cells migration, the expression of neurotrophic factors, and locomotor recovery of contused spinal cord of rats. J Mol Neurosci. 2015;55:760-9 pubmed publisher
Liu C, Hung M, Wang D, Chu P, Su J, Teng T, et al. Tamoxifen induces apoptosis through cancerous inhibitor of protein phosphatase 2A-dependent phospho-Akt inactivation in estrogen receptor-negative human breast cancer cells. Breast Cancer Res. 2014;16:431 pubmed publisher
Abdou H, Bergeron F, Tremblay J. A cell-autonomous molecular cascade initiated by AMP-activated protein kinase represses steroidogenesis. Mol Cell Biol. 2014;34:4257-71 pubmed publisher
Mizunami M, Nemoto Y, Terao K, Hamanaka Y, Matsumoto Y. Roles of calcium/calmodulin-dependent kinase II in long-term memory formation in crickets. PLoS ONE. 2014;9:e107442 pubmed publisher
Tilley D, Zhu W, Myers V, Barr L, Gao E, Li X, et al. β-adrenergic receptor-mediated cardiac contractility is inhibited via vasopressin type 1A-receptor-dependent signaling. Circulation. 2014;130:1800-11 pubmed publisher
Nath S, Munsie L, Truant R. A huntingtin-mediated fast stress response halting endosomal trafficking is defective in Huntington's disease. Hum Mol Genet. 2015;24:450-62 pubmed publisher
Werner K, Neumann D, Seifert R. Analysis of the histamine H2-receptor in human monocytes. Biochem Pharmacol. 2014;92:369-79 pubmed publisher
Lalevée S, Lapaire O, Bühler M. miR455 is linked to hypoxia signaling and is deregulated in preeclampsia. Cell Death Dis. 2014;5:e1408 pubmed publisher
Radeva M, Kugelmann D, Spindler V, Waschke J. PKA compartmentalization via AKAP220 and AKAP12 contributes to endothelial barrier regulation. PLoS ONE. 2014;9:e106733 pubmed publisher
Park H, Baek K, Baek J, Kim H. The cooperation of CREB and NFAT is required for PTHrP-induced RANKL expression in mouse osteoblastic cells. J Cell Physiol. 2015;230:667-79 pubmed publisher
Hoffmann K, Lutz D, Straßburger J, Baqi Y, Müller C, von Kügelgen I. Competitive mode and site of interaction of ticagrelor at the human platelet P2Y12 -receptor. J Thromb Haemost. 2014;12:1898-905 pubmed publisher
Andreu Z, Khan M, González Gómez P, Negueruela S, Hortigüela R, San Emeterio J, et al. The cyclin-dependent kinase inhibitor p27 kip1 regulates radial stem cell quiescence and neurogenesis in the adult hippocampus. Stem Cells. 2015;33:219-29 pubmed publisher
Schuh C, Heher P, Weihs A, Banerjee A, Fuchs C, Gabriel C, et al. In vitro extracorporeal shock wave treatment enhances stemness and preserves multipotency of rat and human adipose-derived stem cells. Cytotherapy. 2014;16:1666-78 pubmed publisher
Jin D, Ni T, Sun J, Wan H, Amack J, Yu G, et al. Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport. Nat Cell Biol. 2014;16:841-51 pubmed publisher
Farnsworth N, Hemmati A, Pozzoli M, Benninger R. Fluorescence recovery after photobleaching reveals regulation and distribution of connexin36 gap junction coupling within mouse islets of Langerhans. J Physiol. 2014;592:4431-46 pubmed publisher
Johansson M, Fransson D, Rundlöf T, Huynh N, Arvidsson T. A general analytical platform and strategy in search for illegal drugs. J Pharm Biomed Anal. 2014;100:215-229 pubmed publisher
Moriya S, Hayata T, Notomi T, Aryal S, Nakamaoto T, Izu Y, et al. PTH regulates β2-adrenergic receptor expression in osteoblast-like MC3T3-E1 cells. J Cell Biochem. 2015;116:142-8 pubmed publisher
Cassar M, Issa A, Riemensperger T, Petitgas C, Rival T, Coulom H, et al. A dopamine receptor contributes to paraquat-induced neurotoxicity in Drosophila. Hum Mol Genet. 2015;24:197-212 pubmed publisher
Kashima K, Watanabe M, Sato Y, Hata J, Ishii N, Aoki Y. Inhibition of metastasis of rhabdomyosarcoma by a novel neutralizing antibody to CXC chemokine receptor-4. Cancer Sci. 2014;105:1343-50 pubmed publisher
Li M, Christie H, Leatherland J. Modulation of GR activity does not affect the in vitro metabolism of cortisol by rainbow trout ovarian follicles. Fish Physiol Biochem. 2014;40:1887-97 pubmed publisher
Liu T, Li H, Gounko N, Zhou Z, Xu A, Hong W, et al. Detection of insulin granule exocytosis by an electrophysiology method with high temporal resolution reveals enlarged insulin granule pool in BIG3-knockout mice. Am J Physiol Endocrinol Metab. 2014;307:E611-8 pubmed publisher
Jiang M, Guo Z, Wang C, Yang Y, Liang X, Ding F. Neural activity analysis of pure chito-oligomer components separated from a mixture of chitooligosaccharides. Neurosci Lett. 2014;581:32-6 pubmed publisher
Saia R, Mestriner F, Bertozi G, Cunha F, Carnio E. Cholecystokinin inhibits inducible nitric oxide synthase expression by lipopolysaccharide-stimulated peritoneal macrophages. Mediators Inflamm. 2014;2014:896029 pubmed publisher
Jiang M, Cheng Q, Su W, Wang C, Yang Y, Cao Z, et al. The beneficial effect of chitooligosaccharides on cell behavior and function of primary Schwann cells is accompanied by up-regulation of adhesion proteins and neurotrophins. Neurochem Res. 2014;39:2047-57 pubmed publisher
Xia S, Ma J, Bai X, Zhang H, Cheng S, Zhang M, et al. Prostaglandin E2 promotes the cell growth and invasive ability of hepatocellular carcinoma cells by upregulating c-Myc expression via EP4 receptor and the PKA signaling pathway. Oncol Rep. 2014;32:1521-30 pubmed publisher
Li C, Rainnie D. Bidirectional regulation of synaptic plasticity in the basolateral amygdala induced by the D1-like family of dopamine receptors and group II metabotropic glutamate receptors. J Physiol. 2014;592:4329-51 pubmed publisher
Wang Y, Sato M, Guo Y, Bengtsson T, Nedergaard J. Protein kinase a-mediated cell proliferation in brown preadipocytes is independent of Erk1/2, PI3K and mTOR. Exp Cell Res. 2014;328:143-55 pubmed publisher
Penumarti A, Abdel Rahman A. Neuronal nitric oxide synthase-dependent elevation in adiponectin in the rostral ventrolateral medulla underlies g protein-coupled receptor 18-mediated hypotension in conscious rats. J Pharmacol Exp Ther. 2014;351:44-53 pubmed publisher
Abedi H, Aghaei M, Panjehpour M, Hajiahmadi S. Mitochondrial and caspase pathways are involved in the induction of apoptosis by IB-MECA in ovarian cancer cell lines. Tumour Biol. 2014;35:11027-39 pubmed publisher
Malvezi A, Panis C, da Silva R, de Freitas R, Lovo Martins M, Tatakihara V, et al. Inhibition of cyclooxygenase-1 and cyclooxygenase-2 impairs Trypanosoma cruzi entry into cardiac cells and promotes differential modulation of the inflammatory response. Antimicrob Agents Chemother. 2014;58:6157-64 pubmed publisher
Allen K, Gourov A, HARTE C, Gao P, Lee C, Sylvain D, et al. Nucleolar integrity is required for the maintenance of long-term synaptic plasticity. PLoS ONE. 2014;9:e104364 pubmed publisher
Zuchero J. Purification of dorsal root ganglion neurons from rat by immunopanning. Cold Spring Harb Protoc. 2014;2014:826-38 pubmed publisher
Efird W, Kellam P, Yeazell S, Weinhold P, Dahners L. An evaluation of prophylactic treatments to prevent post traumatic joint stiffness. J Orthop Res. 2014;32:1520-4 pubmed publisher
Kim E, Park S, Goh M, Na Y, Jo D, Jo Y, et al. Mitochondrial dynamics regulate melanogenesis through proteasomal degradation of MITF via ROS-ERK activation. Pigment Cell Melanoma Res. 2014;27:1051-62 pubmed publisher
Docanto M, Yang F, Callaghan B, Au C, Ragavan R, Wang X, et al. Ghrelin and des-acyl ghrelin inhibit aromatase expression and activity in human adipose stromal cells: suppression of cAMP as a possible mechanism. Breast Cancer Res Treat. 2014;147:193-201 pubmed publisher
Saha A, Biswas A, Srivastav S, Mukherjee M, Das P, Ukil A. Prostaglandin E2 negatively regulates the production of inflammatory cytokines/chemokines and IL-17 in visceral leishmaniasis. J Immunol. 2014;193:2330-9 pubmed publisher
Li M, Liu J, Wang S, Xu H, Cui L, Lv S, et al. Multipotent neural crest stem cell-like cells from rat vibrissa dermal papilla induce neuronal differentiation of PC12 cells. Biomed Res Int. 2014;2014:186239 pubmed publisher
Sodhi P, Hartwick A. Adenosine modulates light responses of rat retinal ganglion cell photoreceptors througha cAMP-mediated pathway. J Physiol. 2014;592:4201-20 pubmed publisher
Godoy V, Banales J, Medina J, Pastor Anglada M. Functional crosstalk between the adenosine transporter CNT3 and purinergic receptors in the biliary epithelia. J Hepatol. 2014;61:1337-43 pubmed publisher
Gassaway M, Rives M, Kruegel A, Javitch J, Sames D. The atypical antidepressant and neurorestorative agent tianeptine is a μ-opioid receptor agonist. Transl Psychiatry. 2014;4:e411 pubmed publisher
Kim K, Egan J, Jang H. Denatonium induces secretion of glucagon-like peptide-1 through activation of bitter taste receptor pathways. Diabetologia. 2014;57:2117-25 pubmed publisher
Walther S, Pluteanu F, Renz S, Nikonova Y, Maxwell J, Yang L, et al. Urocortin 2 stimulates nitric oxide production in ventricular myocytes via Akt- and PKA-mediated phosphorylation of eNOS at serine 1177. Am J Physiol Heart Circ Physiol. 2014;307:H689-700 pubmed publisher
Nishiyama K, Hirai K. The melatonin agonist ramelteon induces duration-dependent clock gene expression through cAMP signaling in pancreatic INS-1 ?-cells. PLoS ONE. 2014;9:e102073 pubmed publisher
Mohamed A, Blanchard M, Albertelli M, Barbieri F, Brue T, Niccoli P, et al. Pasireotide and octreotide antiproliferative effects and sst2 trafficking in human pancreatic neuroendocrine tumor cultures. Endocr Relat Cancer. 2014;21:691-704 pubmed publisher
Dueñas F, Becerra V, Cortes Y, Vidal S, Saenz L, Palomino J, et al. Hepatogenic and neurogenic differentiation of bone marrow mesenchymal stem cells from abattoir-derived bovine fetuses. BMC Vet Res. 2014;10:154 pubmed publisher
Cuppoletti J, Chakrabarti J, Tewari K, Malinowska D. Differentiation between human ClC-2 and CFTR Cl- channels with pharmacological agents. Am J Physiol Cell Physiol. 2014;307:C479-92 pubmed publisher
Motoyoshi S, Yamamoto Y, Munesue S, Igawa H, Harashima A, Saito H, et al. cAMP ameliorates inflammation by modulation of macrophage receptor for advanced glycation end-products. Biochem J. 2014;463:75-82 pubmed publisher
Frizzell C, Elliott C, Connolly L. Effects of the mycotoxin patulin at the level of nuclear receptor transcriptional activity and steroidogenesis in vitro. Toxicol Lett. 2014;229:366-73 pubmed publisher
Hendrick S, Mroz M, Greene C, Keely S, Harvey B. Bile acids stimulate chloride secretion through CFTR and calcium-activated Cl- channels in Calu-3 airway epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2014;307:L407-18 pubmed publisher
Kang T, Choi S, Yang S, Shin T, Kim H, Yu K, et al. Growth arrest and forced differentiation of human primary glioblastoma multiforme by a novel small molecule. Sci Rep. 2014;4:5546 pubmed publisher
Pellitteri R, Catania M, Bonaccorso C, Ranno E, Dell Albani P, Zaccheo D. Viability of olfactory ensheathing cells after hypoxia and serum deprivation: Implication for therapeutic transplantation. J Neurosci Res. 2014;92:1757-66 pubmed publisher
Uhl S, Mathar I, Vennekens R, Freichel M. Adenylyl cyclase-mediated effects contribute to increased Isoprenaline-induced cardiac contractility in TRPM4-deficient mice. J Mol Cell Cardiol. 2014;74:307-17 pubmed publisher
Horvath G, Gölöncsér F, Csölle C, Kiraly K, Ando R, Baranyi M, et al. Central P2Y12 receptor blockade alleviates inflammatory and neuropathic pain and cytokine production in rodents. Neurobiol Dis. 2014;70:162-78 pubmed publisher
Peters M, Bletsch M, Stanley J, Wheeler D, Scott R, Tully T. The PDE4 inhibitor HT-0712 improves hippocampus-dependent memory in aged mice. Neuropsychopharmacology. 2014;39:2938-48 pubmed publisher
Davies J, Bain S, Kanamarlapudi V. ADP-ribosylation factor 6 regulates endothelin-1-induced lipolysis in adipocytes. Biochem Pharmacol. 2014;90:406-13 pubmed publisher
Rojas A, Gueorguieva P, Lelutiu N, Quan Y, Shaw R, Dingledine R. The prostaglandin EP1 receptor potentiates kainate receptor activation via a protein kinase C pathway and exacerbates status epilepticus. Neurobiol Dis. 2014;70:74-89 pubmed publisher
Quadrato G, Elnaggar M, Duman C, Sabino A, Forsberg K, Di Giovanni S. Modulation of GABAA receptor signaling increases neurogenesis and suppresses anxiety through NFATc4. J Neurosci. 2014;34:8630-45 pubmed publisher
Chao C, Chan P, Kuo C, Gong C, Cheng T, Liu Z, et al. Protection of differentiated neuronal NG108-15 cells from P2X7 receptor-mediated toxicity by taurine. Pharmacol Rep. 2014;66:576-84 pubmed publisher
Meir T, Durlacher K, Pan Z, Amir G, Richards W, Silver J, et al. Parathyroid hormone activates the orphan nuclear receptor Nurr1 to induce FGF23 transcription. Kidney Int. 2014;86:1106-15 pubmed publisher
Limjeerajarus C, Osathanon T, Manokawinchoke J, Pavasant P. Iloprost up-regulates vascular endothelial growth factor expression in human dental pulp cells in vitro and enhances pulpal blood flow in vivo. J Endod. 2014;40:925-30 pubmed publisher
Zywert A, Szkudelska K, Szkudelski T. Inhibition of phosphodiesterase 3B in insulin-secreting cells of normal and streptozocin-nicotinamide-induced diabetic rats: implications for insulin secretion. J Physiol Pharmacol. 2014;65:425-33 pubmed
Wang Y, Yan M, Zheng G, He L, Yang H. A cell-based, high-throughput homogeneous time-resolved fluorescence assay for the screening of potential κ-opioid receptor agonists. Acta Pharmacol Sin. 2014;35:957-66 pubmed publisher
Li H, Jeong H, Choi Y, Kim J, Choi J, Yeo C, et al. Protein kinase a phosphorylates Dlx3 and regulates the function of Dlx3 during osteoblast differentiation. J Cell Biochem. 2014;115:2004-11 pubmed publisher
Chou J, Ramirez C, Ryba D, Koduri M, Effros R. Prostaglandin E2 promotes features of replicative senescence in chronically activated human CD8+ T cells. PLoS ONE. 2014;9:e99432 pubmed publisher
Vacas E, Muñoz Moreno L, Fernández Martínez A, Bajo A, Sanchez Chapado M, Prieto J, et al. Signalling pathways involved in antitumoral effects of VIP in human renal cell carcinoma A498 cells: VIP induction of p53 expression. Int J Biochem Cell Biol. 2014;53:295-301 pubmed publisher
van Dijk R, Kremer A, Smit W, Van Den Elzen B, van Gulik T, Gouma D, et al. Characterization and treatment of persistent hepatocellular secretory failure. Liver Int. 2015;35:1478-88 pubmed publisher
He S, Choi Y, Choi J, Yeo C, Chun C, Lee K. Protein kinase A regulates the osteogenic activity of Osterix. J Cell Biochem. 2014;115:1808-15 pubmed publisher
Yi J, Wang H, Vilela M, Danuser G, Hahn K. Manipulation of endogenous kinase activity in living cells using photoswitchable inhibitory peptides. ACS Synth Biol. 2014;3:788-95 pubmed publisher
Wang Y, Liu J, Loizidou A, Bugeja L, Warner R, Hawley B, et al. CFTR potentiators partially restore channel function to A561E-CFTR, a cystic fibrosis mutant with a similar mechanism of dysfunction as F508del-CFTR. Br J Pharmacol. 2014;171:4490-503 pubmed publisher
Mendoza Villarroel R, Robert N, Martin L, Brousseau C, Tremblay J. The nuclear receptor NR2F2 activates star expression and steroidogenesis in mouse MA-10 and MLTC-1 Leydig cells. Biol Reprod. 2014;91:26 pubmed publisher
van Neerven S, Krings L, Haastert Talini K, Vogt M, Tolba R, Brook G, et al. Human Schwann cells seeded on a novel collagen-based microstructured nerve guide survive, proliferate, and modify neurite outgrowth. Biomed Res Int. 2014;2014:493823 pubmed publisher
Jansson K, Castillo D, Morris J, Boggs M, Czymmek K, Adams E, et al. Identification of beta-2 as a key cell adhesion molecule in PCa cell neurotropic behavior: a novel ex vivo and biophysical approach. PLoS ONE. 2014;9:e98408 pubmed publisher
Koppes A, Zaccor N, Rivet C, Williams L, Piselli J, Gilbert R, et al. Neurite outgrowth on electrospun PLLA fibers is enhanced by exogenous electrical stimulation. J Neural Eng. 2014;11:046002 pubmed publisher
Yang C, Yang J, Xu X, Yan S, Pan S, Pan X, et al. Vasodilatory effect of 14,15-epoxyeicosatrienoic acid on mesenteric arteries in hypertensive and aged rats. Prostaglandins Other Lipid Mediat. 2014;112:1-8 pubmed publisher
Buhlman L, Damiano M, Bertolin G, Ferrando Miguel R, Lombes A, Brice A, et al. Functional interplay between Parkin and Drp1 in mitochondrial fission and clearance. Biochim Biophys Acta. 2014;1843:2012-26 pubmed publisher
Moeller H, Aroankins T, Slengerik Hansen J, Pisitkun T, Fenton R. Phosphorylation and ubiquitylation are opposing processes that regulate endocytosis of the water channel aquaporin-2. J Cell Sci. 2014;127:3174-83 pubmed publisher
Wang X, Xu X. Long-term survival, axonal growth-promotion, and myelination of Schwann cells grafted into contused spinal cord in adult rats. Exp Neurol. 2014;261:308-19 pubmed publisher
Amanfu R, Saucerman J. Modeling the effects of β1-adrenergic receptor blockers and polymorphisms on cardiac myocyte Ca2+ handling. Mol Pharmacol. 2014;86:222-30 pubmed publisher
De Joussineau C, Sahut Barnola I, Tissier F, Dumontet T, Drelon C, Batisse Lignier M, et al. mTOR pathway is activated by PKA in adrenocortical cells and participates in vivo to apoptosis resistance in primary pigmented nodular adrenocortical disease (PPNAD). Hum Mol Genet. 2014;23:5418-28 pubmed publisher
Young G, Emery E, Mooney E, Tsantoulas C, McNaughton P. Inflammatory and neuropathic pain are rapidly suppressed by peripheral block of hyperpolarisation-activated cyclic nucleotide-gated ion channels. Pain. 2014;155:1708-19 pubmed publisher
Alvarez C, Schachter J, de Sá Pinheiro A, Silva L, Verstraeten S, Persechini P, et al. Regulation of extracellular ATP in human erythrocytes infected with Plasmodium falciparum. PLoS ONE. 2014;9:e96216 pubmed publisher
Yuan Z, Mehta H, Mohammed K, Nasreen N, Roman R, Brantly M, et al. TREM-1 is induced in tumor associated macrophages by cyclo-oxygenase pathway in human non-small cell lung cancer. PLoS ONE. 2014;9:e94241 pubmed publisher
Fischer J, Aulmann A, Dexheimer V, Grossner T, Richter W. Intermittent PTHrP(1-34) exposure augments chondrogenesis and reduces hypertrophy of mesenchymal stromal cells. Stem Cells Dev. 2014;23:2513-23 pubmed publisher
Brewer M, Ma K, Beecham G, Gopinath C, Baas F, Choi B, et al. Haplotype-specific modulation of a SOX10/CREB response element at the Charcot-Marie-Tooth disease type 4C locus SH3TC2. Hum Mol Genet. 2014;23:5171-87 pubmed publisher
Raslan Z, Naseem K. Compartmentalisation of cAMP-dependent signalling in blood platelets: The role of lipid rafts and actin polymerisation. Platelets. 2015;26:349-57 pubmed publisher
Young G, Gutteridge A, Fox H, Wilbrey A, Cao L, Cho L, et al. Characterizing human stem cell-derived sensory neurons at the single-cell level reveals their ion channel expression and utility in pain research. Mol Ther. 2014;22:1530-1543 pubmed publisher
De Martin S, Paliuri G, Belloni A, Orso G, Zanarella E, Stellin G, et al. Expression and distribution of the adrenomedullin system in newborn human thymus. PLoS ONE. 2014;9:e97592 pubmed publisher
Sandvig I, Karstensen K, Rokstad A, Aachmann F, Formo K, Sandvig A, et al. RGD-peptide modified alginate by a chemoenzymatic strategy for tissue engineering applications. J Biomed Mater Res A. 2015;103:896-906 pubmed publisher
Aihara M, Chen Y, Uchida S, Nakayama M, Araie M. Hyperbaric pressure and increased susceptibility to glutamate toxicity in retinal ganglion cells in vitro. Mol Vis. 2014;20:606-15 pubmed
Almami I, Dickenson J, Hargreaves A, Bonner P. Modulation of transglutaminase 2 activity in H9c2 cells by PKC and PKA signalling: a role for transglutaminase 2 in cytoprotection. Br J Pharmacol. 2014;171:3946-60 pubmed publisher
Safa M, Mousavizadeh K, Noori S, Pourfathollah A, Zand H. cAMP protects acute promyelocytic leukemia cells from arsenic trioxide-induced caspase-3 activation and apoptosis. Eur J Pharmacol. 2014;736:115-23 pubmed publisher
Vargas A, Zhou S, Ethier Chiasson M, Flipo D, Lafond J, Gilbert C, et al. Syncytin proteins incorporated in placenta exosomes are important for cell uptake and show variation in abundance in serum exosomes from patients with preeclampsia. FASEB J. 2014;28:3703-19 pubmed publisher
Jiang Y, Kou Z, Wu T, An W, Zhou R, Wang H, et al. Xist deficiency and disorders of X-inactivation in rabbit embryonic stem cells can be rescued by transcription-factor-mediated conversion. Stem Cells Dev. 2014;23:2283-96 pubmed publisher
Kolar M, Kingham P, Novikova L, Wiberg M, Novikov L. The therapeutic effects of human adipose-derived stem cells in a rat cervical spinal cord injury model. Stem Cells Dev. 2014;23:1659-74 pubmed publisher
Zhao H, Wei R, Wang L, Tian Q, Tao M, Ke J, et al. Activation of glucagon-like peptide-1 receptor inhibits growth and promotes apoptosis of human pancreatic cancer cells in a cAMP-dependent manner. Am J Physiol Endocrinol Metab. 2014;306:E1431-41 pubmed publisher
Liu X, Grandy D, Janowsky A. Ractopamine, a livestock feed additive, is a full agonist at trace amine-associated receptor 1. J Pharmacol Exp Ther. 2014;350:124-9 pubmed publisher
di Summa P, Kingham P, Campisi C, Raffoul W, Kalbermatten D. Collagen (NeuraGen®) nerve conduits and stem cells for peripheral nerve gap repair. Neurosci Lett. 2014;572:26-31 pubmed publisher
Krabbe C, Bak S, Jensen P, von Linstow C, Martinez Serrano A, Hansen C, et al. Influence of oxygen tension on dopaminergic differentiation of human fetal stem cells of midbrain and forebrain origin. PLoS ONE. 2014;9:e96465 pubmed publisher
França F, Ferreira A, Lara R, Rossoni J, Costa D, Moraes K, et al. Role of protein kinase A signaling pathway in cyclosporine nephrotoxicity. Toxicol Mech Methods. 2014;24:369-76 pubmed publisher
Cano Peñalver J, Griera M, Serrano I, Rodriguez Puyol D, Dedhar S, de Frutos S, et al. Integrin-linked kinase regulates tubular aquaporin-2 content and intracellular location: a link between the extracellular matrix and water reabsorption. FASEB J. 2014;28:3645-59 pubmed publisher
Lee M, Cho K, Park H, Sung H, Choi S, Im W. Pharmacological profile of DA-6886, a novel 5-HT4 receptor agonist to accelerate colonic motor activity in mice. Eur J Pharmacol. 2014;735:115-22 pubmed publisher
Mitchell R, Szabo E, Shapovalova Z, Aslostovar L, Makondo K, Bhatia M. Molecular evidence for OCT4-induced plasticity in adult human fibroblasts required for direct cell fate conversion to lineage specific progenitors. Stem Cells. 2014;32:2178-87 pubmed publisher
Wu S, Chiu H, Chin Y, Lin H, Chiang C, Tu H, et al. Effects of enamel matrix derivative on the proliferation and osteogenic differentiation of human gingival mesenchymal stem cells. Stem Cell Res Ther. 2014;5:52 pubmed publisher
Yang Y, Yang W, Yu T, Sung G, Park K, Yoon K, et al. ATF-2/CREB/IRF-3-targeted anti-inflammatory activity of Korean red ginseng water extract. J Ethnopharmacol. 2014;154:218-28 pubmed publisher
Jesuraj N, Marquardt L, Kwasa J, Sakiyama Elbert S. Glial cell line-derived neurotrophic factor promotes increased phenotypic marker expression in femoral sensory and motor-derived Schwann cell cultures. Exp Neurol. 2014;257:10-8 pubmed publisher
Gossan N, Zhang F, Guo B, Jin D, Yoshitane H, Yao A, et al. The E3 ubiquitin ligase UBE3A is an integral component of the molecular circadian clock through regulating the BMAL1 transcription factor. Nucleic Acids Res. 2014;42:5765-75 pubmed publisher
Gautherot J, Delautier D, Maubert M, Ait Slimane T, Bolbach G, Delaunay J, et al. Phosphorylation of ABCB4 impacts its function: insights from disease-causing mutations. Hepatology. 2014;60:610-21 pubmed publisher
Svensson E, Proekt A, Jing J, Weiss K. PKC-mediated GABAergic enhancement of dopaminergic responses: implication for short-term potentiation at a dual-transmitter synapse. J Neurophysiol. 2014;112:22-9 pubmed publisher
Zhai B, Hu F, Jiang X, Xu J, Zhao D, Liu B, et al. Inhibition of Akt reverses the acquired resistance to sorafenib by switching protective autophagy to autophagic cell death in hepatocellular carcinoma. Mol Cancer Ther. 2014;13:1589-98 pubmed publisher
Cooke A, Oldfield S, Krasel C, Mundell S, Henderson G, Kelly E. Morphine-induced internalization of the L83I mutant of the rat ?-opioid receptor. Br J Pharmacol. 2015;172:593-605 pubmed publisher
Hall J, Tabata M, Rodgers J, Puigserver P. USP7 attenuates hepatic gluconeogenesis through modulation of FoxO1 gene promoter occupancy. Mol Endocrinol. 2014;28:912-24 pubmed publisher
Maimon N, Titus P, Sarelius I. Pre-exposure to adenosine, acting via A(2A) receptors on endothelial cells, alters the protein kinase A dependence of adenosine-induced dilation in skeletal muscle resistance arterioles. J Physiol. 2014;592:2575-90 pubmed publisher
Landreh L, Spinnler K, Schubert K, Häkkinen M, Auriola S, Poutanen M, et al. Human testicular peritubular cells host putative stem Leydig cells with steroidogenic capacity. J Clin Endocrinol Metab. 2014;99:E1227-35 pubmed publisher
Chiang Y, Ip W, Shao W, Song Z, Chernoff J, Jin T. Activation of cAMP signaling attenuates impaired hepatic glucose disposal in aged male p21-activated protein kinase-1 knockout mice. Endocrinology. 2014;155:2122-32 pubmed publisher
Uchida M, Ito T, Nakamura T, Hijioka M, Igarashi H, Oono T, et al. Pancreatic stellate cells and CX3CR1: occurrence in normal pancreas and acute and chronic pancreatitis and effect of their activation by a CX3CR1 agonist. Pancreas. 2014;43:708-19 pubmed publisher
Breton A, Fox J, Brownson M, McEchron M. Postnatal nutritional iron deficiency impairs dopaminergic-mediated synaptic plasticity in the CA1 area of the hippocampus. Nutr Neurosci. 2015;18:241-7 pubmed publisher
Karakaya C, Guzeloglu Kayisli O, Hobbs R, Gerasimova T, Uyar A, Erdem M, et al. Follicle-stimulating hormone receptor (FSHR) alternative skipping of exon 2 or 3 affects ovarian response to FSH. Mol Hum Reprod. 2014;20:630-43 pubmed publisher
Marchetti T, Ruffatti A, Wuillemin C, de Moerloose P, Cohen M. Hydroxychloroquine restores trophoblast fusion affected by antiphospholipid antibodies. J Thromb Haemost. 2014;12:910-20 pubmed publisher
Madishetti S, Schneble N, König C, Hirsch E, Schulz S, Müller J, et al. PI3Kγ integrates cAMP and Akt signalling of the μ-opioid receptor. Br J Pharmacol. 2014;171:3328-37 pubmed publisher
Piao L, Park J, Li Y, Shin S, Shin S, Kong G, et al. SOCS3 and SOCS6 are required for the risperidone-mediated inhibition of insulin and leptin signaling in neuroblastoma cells. Int J Mol Med. 2014;33:1364-70 pubmed publisher
Stati T, Musumeci M, Maccari S, Massimi A, Corritore E, Strimpakos G, et al. β-Blockers promote angiogenesis in the mouse aortic ring assay. J Cardiovasc Pharmacol. 2014;64:21-7 pubmed publisher
Fu X, Liu S, Dan Q, Wang Y, Lin N, Lv L, et al. Combined Bone Mesenchymal Stem Cell and Olfactory Ensheathing Cell Transplantation Promotes Neural Repair Associated With CNTF Expression in Traumatic Brain-Injured Rats. Cell Transplant. 2015;24:1533-44 pubmed publisher
Degraaf A, Zasłona Z, Bourdonnay E, Peters Golden M. Prostaglandin E2 reduces Toll-like receptor 4 expression in alveolar macrophages by inhibition of translation. Am J Respir Cell Mol Biol. 2014;51:242-50 pubmed publisher
Peng Y, Deng L, Ding Y, Chen Q, Wu Y, Yang M, et al. Comparative study of somatostatin-human serum albumin fusion proteins and natural somatostatin on receptor binding, internalization and activation. PLoS ONE. 2014;9:e89932 pubmed publisher
van der Hagen E, Lavrijsen M, van Zeeland F, Praetorius J, Bonny O, Bindels R, et al. Coordinated regulation of TRPV5-mediated Ca²⁺ transport in primary distal convolution cultures. Pflugers Arch. 2014;466:2077-87 pubmed publisher
Mottillo E, Paul G, Moore H, Granneman J. Use of fluorescence microscopy to probe intracellular lipolysis. Methods Enzymol. 2014;538:263-78 pubmed publisher
Nagpure B, Bian J. Hydrogen sulfide inhibits A2A adenosine receptor agonist induced β-amyloid production in SH-SY5Y neuroblastoma cells via a cAMP dependent pathway. PLoS ONE. 2014;9:e88508 pubmed publisher
Kang T, Leem S. Modulation of ATR-mediated DNA damage checkpoint response by cryptochrome 1. Nucleic Acids Res. 2014;42:4427-34 pubmed publisher
Laidlaw T, Cutler A, Kidder M, Liu T, Cardet J, Chhay H, et al. Prostaglandin E2 resistance in granulocytes from patients with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol. 2014;133:1692-701.e3 pubmed publisher
Van Raemdonck K, Gouwy M, Lepers S, Van Damme J, Struyf S. CXCL4L1 and CXCL4 signaling in human lymphatic and microvascular endothelial cells and activated lymphocytes: involvement of mitogen-activated protein (MAP) kinases, Src and p70S6 kinase. Angiogenesis. 2014;17:631-40 pubmed publisher
Ulloa S, Heinzmann J, Herrmann D, Timmermann B, Baulain U, Großfeld R, et al. Effects of different oocyte retrieval and in vitro maturation systems on bovine embryo development and quality. Zygote. 2015;23:367-77 pubmed publisher
Felizola S, Nakamura Y, Ono Y, Kitamura K, Kikuchi K, Onodera Y, et al. PCP4: a regulator of aldosterone synthesis in human adrenocortical tissues. J Mol Endocrinol. 2014;52:159-67 pubmed publisher
Gao X, Lu Q, Chou G, Wang Z, Pan R, Xia Y, et al. Norisoboldine attenuates inflammatory pain via the adenosine A1 receptor. Eur J Pain. 2014;18:939-48 pubmed publisher
Jeong J, Park Y, Kim D, Lee S, Kwak Y, Lee S, et al. Cdk5 phosphorylates dopamine D2 receptor and attenuates downstream signaling. PLoS ONE. 2013;8:e84482 pubmed publisher
de Luca B, Xavier Elsas P, Barradas M, Luz R, Queto T, Jones C, et al. Essential roles of PKA, iNOS, CD95/CD95L, and terminal caspases in suppression of eosinopoiesis by PGE2 and other cAMP-elevating agents. ScientificWorldJournal. 2013;2013:208705 pubmed publisher
Bhattacherjee A, Liao Z, Smith P. Trophic factor and hormonal regulation of neurite outgrowth in sensory neuron-like 50B11 cells. Neurosci Lett. 2014;558:120-5 pubmed publisher
Schlatter E, Klassen P, Massmann V, Holle S, Guckel D, Edemir B, et al. Mouse organic cation transporter 1 determines properties and regulation of basolateral organic cation transport in renal proximal tubules. Pflugers Arch. 2014;466:1581-9 pubmed
Wang Y, Hu Z, Liu Z, Chen R, Peng H, Guo J, et al. MTOR inhibition attenuates DNA damage and apoptosis through autophagy-mediated suppression of CREB1. Autophagy. 2013;9:2069-86 pubmed publisher
Johnston P, Sen M, Hua Y, Camarco D, Shun T, Lazo J, et al. High-content pSTAT3/1 imaging assays to screen for selective inhibitors of STAT3 pathway activation in head and neck cancer cell lines. Assay Drug Dev Technol. 2014;12:55-79 pubmed publisher
Zimmerman N, Roy I, Hauser A, Wilson J, Williams C, Dwinell M. Cyclic AMP regulates the migration and invasion potential of human pancreatic cancer cells. Mol Carcinog. 2015;54:203-15 pubmed publisher
Xu X, Prough R, Samuelson D. Differential 12-O-Tetradecanoylphorbol-13-acetate-induced activation of rat mammary carcinoma susceptibility Fbxo10 variant promoters via a PKC-AP1 pathway. Mol Carcinog. 2015;54:134-47 pubmed publisher
Emery B, Dugas J. Purification of oligodendrocyte lineage cells from mouse cortices by immunopanning. Cold Spring Harb Protoc. 2013;2013:854-68 pubmed publisher
He W, Wilder T, Cronstein B. Rolofylline, an adenosine A1 receptor antagonist, inhibits osteoclast differentiation as an inverse agonist. Br J Pharmacol. 2013;170:1167-76 pubmed publisher
Petrilli A, Copik A, Posadas M, Chang L, Welling D, Giovannini M, et al. LIM domain kinases as potential therapeutic targets for neurofibromatosis type 2. Oncogene. 2014;33:3571-82 pubmed publisher
Dugas J, Emery B. Purification of oligodendrocyte precursor cells from rat cortices by immunopanning. Cold Spring Harb Protoc. 2013;2013:745-58 pubmed publisher
Winzeler A, Wang J. Purification and culture of retinal ganglion cells from rodents. Cold Spring Harb Protoc. 2013;2013:643-52 pubmed publisher
Trinh A, Kim S, Chang H, Mastrocola A, Tibbetts R. Cyclin-dependent kinase 1-dependent phosphorylation of cAMP response element-binding protein decreases chromatin occupancy. J Biol Chem. 2013;288:23765-75 pubmed publisher
Dong W, Chen J, He Y, Xu J, Mei Y. Resveratrol inhibits K(v)2.2 currents through the estrogen receptor GPR30-mediated PKC pathway. Am J Physiol Cell Physiol. 2013;305:C547-57 pubmed publisher
Garcia Murillas I, Sharpe R, Pearson A, Campbell J, Natrajan R, Ashworth A, et al. An siRNA screen identifies the GNAS locus as a driver in 20q amplified breast cancer. Oncogene. 2014;33:2478-86 pubmed publisher
Guibinga G, Murray F, Barron N. HPRT-deficiency dysregulates cAMP-PKA signaling and phosphodiesterase 10A expression: mechanistic insight and potential target for Lesch-Nyhan Disease?. PLoS ONE. 2013;8:e63333 pubmed publisher
Lazzeroni G, Benicchi T, Heitz F, Magnoni L, Diamanti D, Rossini L, et al. A phenotypic screening assay for modulators of huntingtin-induced transcriptional dysregulation. J Biomol Screen. 2013;18:984-96 pubmed publisher
Pondugula S, Kampalli S, Wu T, De Lisle R, Raveendran N, Harbidge D, et al. cAMP-stimulated Cl- secretion is increased by glucocorticoids and inhibited by bumetanide in semicircular canal duct epithelium. BMC Physiol. 2013;13:6 pubmed publisher
El Kheir W, Gabr H, Awad M, Ghannam O, Barakat Y, Farghali H, et al. Autologous bone marrow-derived cell therapy combined with physical therapy induces functional improvement in chronic spinal cord injury patients. Cell Transplant. 2014;23:729-45 pubmed publisher
Chang Z, Yeh M, Chiang C, Chen Y, Lu D. Erythropoietin protects adult retinal ganglion cells against NMDA-, trophic factor withdrawal-, and TNF-?-induced damage. PLoS ONE. 2013;8:e55291 pubmed publisher
Liu C, Teng Z, McQuate A, Jobe E, Christ C, von Hoyningen Huene S, et al. An epigenetic feedback regulatory loop involving microRNA-195 and MBD1 governs neural stem cell differentiation. PLoS ONE. 2013;8:e51436 pubmed publisher
Wu J, Chen C, Wang C, Ho M, Yeh M, Wang Y. Low-power laser irradiation suppresses inflammatory response of human adipose-derived stem cells by modulating intracellular cyclic AMP level and NF-?B activity. PLoS ONE. 2013;8:e54067 pubmed publisher
Holloway K, Barbieri A, Malyarchuk S, Saxena M, Nedeljkovic Kurepa A, Cameron Mehl M, et al. SIRT1 positively regulates breast cancer associated human aromatase (CYP19A1) expression. Mol Endocrinol. 2013;27:480-90 pubmed publisher
Jensen P, Lyck L, Jensen P, Zimmer J, Meyer M. Characterization of Porcine Ventral Mesencephalic Precursor Cells following Long-Term Propagation in 3D Culture. Stem Cells Int. 2012;2012:761843 pubmed publisher
Langworthy M, Appel B. Schwann cell myelination requires Dynein function. Neural Dev. 2012;7:37 pubmed publisher
Guo W, Patzlaff N, Jobe E, Zhao X. Isolation of multipotent neural stem or progenitor cells from both the dentate gyrus and subventricular zone of a single adult mouse. Nat Protoc. 2012;7:2005-12 pubmed publisher
Park S, Lee S, Baek S, Lee C, Lee W, Rhim B, et al. Suppression of PU.1-linked TLR4 expression by cilostazol with decrease of cytokine production in macrophages from patients with rheumatoid arthritis. Br J Pharmacol. 2013;168:1401-11 pubmed publisher
Terrin A, Monterisi S, Stangherlin A, Zoccarato A, Koschinski A, Surdo N, et al. PKA and PDE4D3 anchoring to AKAP9 provides distinct regulation of cAMP signals at the centrosome. J Cell Biol. 2012;198:607-21 pubmed publisher
Koeppen K, Chapline C, Sato J, Stanton B. Nedd4-2 does not regulate wt-CFTR in human airway epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2012;303:L720-7 pubmed publisher
Luciani A, Villella V, Esposito S, Gavina M, Russo I, Silano M, et al. Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ?F508 cystic fibrosis transmembrane conductance regulator. Autophagy. 2012;8:1657-72 pubmed publisher
Kao R, Lu W, Louie A, NISSENSON R. Cyclic AMP signaling in bone marrow stromal cells has reciprocal effects on the ability of mesenchymal stem cells to differentiate into mature osteoblasts versus mature adipocytes. Endocrine. 2012;42:622-36 pubmed publisher
Lee D, Lee H, Hong S, Choi B, Kim H, Han S, et al. Inositol 1,4,5-trisphosphate 3-kinase A is a novel microtubule-associated protein: PKA-dependent phosphoregulation of microtubule binding affinity. J Biol Chem. 2012;287:15981-95 pubmed publisher
Zhou H, Gao J, Zhou L, Li X, Li W, Li X, et al. Ginkgolide B inhibits renal cyst development in in vitro and in vivo cyst models. Am J Physiol Renal Physiol. 2012;302:F1234-42 pubmed publisher
Song B, Avery L. Serotonin activates overall feeding by activating two separate neural pathways in Caenorhabditis elegans. J Neurosci. 2012;32:1920-31 pubmed publisher
del Puerto A, Díaz Hernández J, Tapia M, Gomez Villafuertes R, Benitez M, Zhang J, et al. Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation. J Cell Sci. 2012;125:176-88 pubmed publisher
Sastalla I, Tang S, Crown D, Liu S, Eckhaus M, Hewlett I, et al. Anthrax edema toxin impairs clearance in mice. Infect Immun. 2012;80:529-38 pubmed publisher
Wu M, Liu L, Chan C. Identification of novel targets for breast cancer by exploring gene switches on a genome scale. BMC Genomics. 2011;12:547 pubmed publisher
Crews L, Ruf R, Patrick C, Dumaop W, Trejo Morales M, Achim C, et al. Phosphorylation of collapsin response mediator protein-2 disrupts neuronal maturation in a model of adult neurogenesis: Implications for neurodegenerative disorders. Mol Neurodegener. 2011;6:67 pubmed publisher
Schrader E, Harstad K, Holmgren R, Matouschek A. A three-part signal governs differential processing of Gli1 and Gli3 proteins by the proteasome. J Biol Chem. 2011;286:39051-8 pubmed publisher
Sorio C, Buffelli M, Angiari C, Ettorre M, Johansson J, Vezzalini M, et al. Defective CFTR expression and function are detectable in blood monocytes: development of a new blood test for cystic fibrosis. PLoS ONE. 2011;6:e22212 pubmed publisher
Head B, Hu Y, Finley J, Saldana M, Bonds J, Miyanohara A, et al. Neuron-targeted caveolin-1 protein enhances signaling and promotes arborization of primary neurons. J Biol Chem. 2011;286:33310-21 pubmed publisher
Follin Arbelet V, Hofgaard P, Hauglin H, Naderi S, Sundan A, Blomhoff R, et al. Cyclic AMP induces apoptosis in multiple myeloma cells and inhibits tumor development in a mouse myeloma model. BMC Cancer. 2011;11:301 pubmed publisher
Vockel M, Pollok S, Breitenbach U, Ridderbusch I, Kreienkamp H, Brandner J. Somatostatin inhibits cell migration and reduces cell counts of human keratinocytes and delays epidermal wound healing in an ex vivo wound model. PLoS ONE. 2011;6:e19740 pubmed publisher
Hughes A, Guilding C, Piggins H. Neuropeptide signaling differentially affects phase maintenance and rhythm generation in SCN and extra-SCN circadian oscillators. PLoS ONE. 2011;6:e18926 pubmed publisher
Fukushima T, Tsuda M, Kofuji T, Hori Y. Physiological properties of enkephalin-containing neurons in the spinal dorsal horn visualized by expression of green fluorescent protein in BAC transgenic mice. BMC Neurosci. 2011;12:36 pubmed publisher
Winzeler A, Mandemakers W, Sun M, Stafford M, Phillips C, Barres B. The lipid sulfatide is a novel myelin-associated inhibitor of CNS axon outgrowth. J Neurosci. 2011;31:6481-92 pubmed publisher
Schulzke J, Andres S, Amasheh M, Fromm A, Gunzel D. Anti-diarrheal mechanism of the traditional remedy Uzara via reduction of active chloride secretion. PLoS ONE. 2011;6:e18107 pubmed publisher
Cho Y, Cho H, Jang S, Jeong H, Park J. Transplantation of neural differentiated human mesenchymal stem cells into the cochlea of an auditory-neuropathy guinea pig model. J Korean Med Sci. 2011;26:492-8 pubmed publisher
Clewes O, Narytnyk A, Gillinder K, Loughney A, Murdoch A, Sieber Blum M. Human epidermal neural crest stem cells (hEPI-NCSC)--characterization and directed differentiation into osteocytes and melanocytes. Stem Cell Rev. 2011;7:799-814 pubmed publisher
Li X, Wang Q, Pan N, Lee S, Zhao Y, Chait B, et al. Phosphorylation-dependent 14-3-3 binding to LRRK2 is impaired by common mutations of familial Parkinson's disease. PLoS ONE. 2011;6:e17153 pubmed publisher
Laohapitakworn S, Thongbunchoo J, Nakkrasae L, Krishnamra N, Charoenphandhu N. Parathyroid hormone (PTH) rapidly enhances CFTR-mediated HCO?? secretion in intestinal epithelium-like Caco-2 monolayer: a novel ion regulatory action of PTH. Am J Physiol Cell Physiol. 2011;301:C137-49 pubmed publisher
Kasper L, Thomas M, Zambetti G, Brindle P. Double null cells reveal that CBP and p300 are dispensable for p53 targets p21 and Mdm2 but variably required for target genes of other signaling pathways. Cell Cycle. 2011;10:212-21 pubmed
Jiwaji M, Daly R, Pansare K, McLean P, Yang J, Kolch W, et al. The Renilla luciferase gene as a reference gene for normalization of gene expression in transiently transfected cells. BMC Mol Biol. 2010;11:103 pubmed publisher
Hayashi S, Nakata E, Morita A, Mizuno K, Yamamura K, Kato A, et al. Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pai. Bioorg Med Chem. 2010;18:7675-99 pubmed publisher
Crews L, Adame A, Patrick C, DeLaney A, Pham E, Rockenstein E, et al. Increased BMP6 levels in the brains of Alzheimer's disease patients and APP transgenic mice are accompanied by impaired neurogenesis. J Neurosci. 2010;30:12252-62 pubmed publisher
Resende T, Ferreira M, Teillet M, Tavares A, Andrade R, Palmeirim I. Sonic hedgehog in temporal control of somite formation. Proc Natl Acad Sci U S A. 2010;107:12907-12 pubmed publisher
Joubert L, Foucault I, Sagot Y, Bernasconi L, Duval F, Alliod C, et al. Chemical inducers and transcriptional markers of oligodendrocyte differentiation. J Neurosci Res. 2010;88:2546-57 pubmed publisher
Shan Q, Storm D. Optimization of a cAMP response element signal pathway reporter system. J Neurosci Methods. 2010;191:21-5 pubmed publisher
Zhou J, Lal H, Chen X, Shang X, Song J, Li Y, et al. GSK-3alpha directly regulates beta-adrenergic signaling and the response of the heart to hemodynamic stress in mice. J Clin Invest. 2010;120:2280-91 pubmed publisher
Nascimento F, Figueredo S, Marcon R, Martins D, Macedo S, Lima D, et al. Inosine reduces pain-related behavior in mice: involvement of adenosine A1 and A2A receptor subtypes and protein kinase C pathways. J Pharmacol Exp Ther. 2010;334:590-8 pubmed publisher
Rechtman M, Har Noy O, Bar Yishay I, Fishman S, Adamovich Y, Shaul Y, et al. Curcumin inhibits hepatitis B virus via down-regulation of the metabolic coactivator PGC-1alpha. FEBS Lett. 2010;584:2485-90 pubmed publisher
Gris P, Cheng P, Pierson J, Maixner W, Diatchenko L. Molecular assays for characterization of alternatively spliced isoforms of the u opioid receptor (MOR). Methods Mol Biol. 2010;617:421-35 pubmed publisher
Su Z, Yuan Y, Chen J, Cao L, Zhu Y, Gao L, et al. Reactive astrocytes in glial scar attract olfactory ensheathing cells migration by secreted TNF-alpha in spinal cord lesion of rat. PLoS ONE. 2009;4:e8141 pubmed publisher
Hutt D, Herman D, Rodrigues A, Noel S, Pilewski J, Matteson J, et al. Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis. Nat Chem Biol. 2010;6:25-33 pubmed publisher
Staun Ram E, Goldman S, Shalev E. Ets-2 and p53 mediate cAMP-induced MMP-2 expression, activity and trophoblast invasion. Reprod Biol Endocrinol. 2009;7:135 pubmed publisher
Treharne K, Xu Z, Chen J, Best O, Cassidy D, Gruenert D, et al. Inhibition of protein kinase CK2 closes the CFTR Cl channel, but has no effect on the cystic fibrosis mutant deltaF508-CFTR. Cell Physiol Biochem. 2009;24:347-60 pubmed publisher
Wilson S, Shen P, Rider C, Traves S, Proud D, Newton R, et al. Selective prostacyclin receptor agonism augments glucocorticoid-induced gene expression in human bronchial epithelial cells. J Immunol. 2009;183:6788-99 pubmed publisher
Ranganathan P, Chen H, Adelman M, Schluter S. Autoantibodies to the delta-opioid receptor function as opioid agonists and display immunomodulatory activity. J Neuroimmunol. 2009;217:65-73 pubmed publisher
Vega A, Tester D, Ackerman M, Makielski J. Protein kinase A-dependent biophysical phenotype for V227F-KCNJ2 mutation in catecholaminergic polymorphic ventricular tachycardia. Circ Arrhythm Electrophysiol. 2009;2:540-7 pubmed publisher
Tuo B, Wen G, Seidler U. Differential activation of the HCO(3)(-) conductance through the cystic fibrosis transmembrane conductance regulator anion channel by genistein and forskolin in murine duodenum. Br J Pharmacol. 2009;158:1313-21 pubmed publisher
Lee S, Chung C. Role of VASP phosphorylation for the regulation of microglia chemotaxis via the regulation of focal adhesion formation/maturation. Mol Cell Neurosci. 2009;42:382-90 pubmed publisher
Vuchak L, Tsygankova O, Prendergast G, Meinkoth J. Protein kinase A and B-Raf mediate extracellular signal-regulated kinase activation by thyrotropin. Mol Pharmacol. 2009;76:1123-9 pubmed publisher
Ghosh S, Lu Y, Hu Y. A Role of CREB in BRCA1 Constitutive Promoter Activity and Aromatase Basal Expression. Int J Biomed Sci. 2008;4:260-265 pubmed
Mu oz B, Huerta M, L pez Bayghen E. Cilostazol reduces proliferation through c-Myc down-regulation in MDCK cells. Eur J Pharmacol. 2009;616:22-30 pubmed publisher
Butler T, Elustondo P, Hannigan G, MacPhee D. Integrin-linked kinase can facilitate syncytialization and hormonal differentiation of the human trophoblast-derived BeWo cell line. Reprod Biol Endocrinol. 2009;7:51 pubmed publisher
Schnoke M, Midura S, Midura R. Parathyroid hormone suppresses osteoblast apoptosis by augmenting DNA repair. Bone. 2009;45:590-602 pubmed publisher
Harvey A, Ehlert E, De Wit J, Drummond E, Pollett M, Ruitenberg M, et al. Use of GFP to analyze morphology, connectivity, and function of cells in the central nervous system. Methods Mol Biol. 2009;515:63-95 pubmed publisher
Lee T, Packer M, Huang J, Akhmametyeva E, Kulp S, Chen C, et al. Growth inhibitory and anti-tumour activities of OSU-03012, a novel PDK-1 inhibitor, on vestibular schwannoma and malignant schwannoma cells. Eur J Cancer. 2009;45:1709-20 pubmed publisher
Chen J, Hammell D, Spry M, D Orazio J, Stinchcomb A. In vitro skin diffusion study of pure forskolin versus a forskolin-containing Plectranthus barbatus root extract. J Nat Prod. 2009;72:769-71 pubmed publisher
McGuinness D, Malikzay A, Visconti R, Lin K, Bayne M, Monsma F, et al. Characterizing cannabinoid CB2 receptor ligands using DiscoveRx PathHunter beta-arrestin assay. J Biomol Screen. 2009;14:49-58 pubmed publisher
Gobert R, Joubert L, Curchod M, Salvat C, Foucault I, Jorand Lebrun C, et al. Convergent functional genomics of oligodendrocyte differentiation identifies multiple autoinhibitory signaling circuits. Mol Cell Biol. 2009;29:1538-53 pubmed publisher
Huang W, Li C, Wu P, Chang Y, Lee T, Weng C. Expression and in vitro regulation of pituitary adenylate cyclase-activating polypeptide (pacap38) and its type I receptor (pac1-r) in the gonads of tilapia (Oreochromis mossambicus). Reproduction. 2009;137:449-67 pubmed publisher
Ster J, de Bock F, Bertaso F, Abitbol K, Daniel H, Bockaert J, et al. Epac mediates PACAP-dependent long-term depression in the hippocampus. J Physiol. 2009;587:101-13 pubmed publisher
Ericksen S, Cummings D, Weinstein H, Schetz J. Ligand selectivity of D2 dopamine receptors is modulated by changes in local dynamics produced by sodium binding. J Pharmacol Exp Ther. 2009;328:40-54 pubmed publisher
Masri B, Salahpour A, Didriksen M, Ghisi V, Beaulieu J, Gainetdinov R, et al. Antagonism of dopamine D2 receptor/beta-arrestin 2 interaction is a common property of clinically effective antipsychotics. Proc Natl Acad Sci U S A. 2008;105:13656-61 pubmed publisher
Tchedre K, Huang R, Dibas A, Krishnamoorthy R, Dillon G, Yorio T. Sigma-1 receptor regulation of voltage-gated calcium channels involves a direct interaction. Invest Ophthalmol Vis Sci. 2008;49:4993-5002 pubmed publisher
Koo J, Kim H, Yoon H, Kwon K, Choi I, Jung S, et al. Effect of xanthohumol on melanogenesis in B16 melanoma cells. Exp Mol Med. 2008;40:313-9 pubmed
Williams A, Sarkar S, Cuddon P, Ttofi E, Saiki S, Siddiqi F, et al. Novel targets for Huntington's disease in an mTOR-independent autophagy pathway. Nat Chem Biol. 2008;4:295-305 pubmed publisher
Tchedre K, Yorio T. sigma-1 receptors protect RGC-5 cells from apoptosis by regulating intracellular calcium, Bax levels, and caspase-3 activation. Invest Ophthalmol Vis Sci. 2008;49:2577-88 pubmed publisher
Titus S, Neumann S, Zheng W, Southall N, Michael S, Klumpp C, et al. Quantitative high-throughput screening using a live-cell cAMP assay identifies small-molecule agonists of the TSH receptor. J Biomol Screen. 2008;13:120-7 pubmed publisher
Katona B, Cummins C, Ferguson A, Li T, Schmidt D, Mangelsdorf D, et al. Synthesis, characterization, and receptor interaction profiles of enantiomeric bile acids. J Med Chem. 2007;50:6048-58 pubmed
Cordeaux Y, Briddon S, Alexander S, Kellam B, Hill S. Agonist-occupied A3 adenosine receptors exist within heterogeneous complexes in membrane microdomains of individual living cells. FASEB J. 2008;22:850-60 pubmed
Miller K, Barrow J, Collinson J, Davidson S, Lear M, Hill R, et al. A highly conserved Wnt-dependent TCF4 binding site within the proximal enhancer of the anti-myogenic Msx1 gene supports expression within Pax3-expressing limb bud muscle precursor cells. Dev Biol. 2007;311:665-78 pubmed
Wang C, Li G, Huang L. Prostaglandin E2 potentiation of P2X3 receptor mediated currents in dorsal root ganglion neurons. Mol Pain. 2007;3:22 pubmed
Wen C, Kuo Y, Jan J, Liang P, Wang S, Liu H, et al. Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus. J Med Chem. 2007;50:4087-95 pubmed
Zhao Y, Ding S. A high-throughput siRNA library screen identifies osteogenic suppressors in human mesenchymal stem cells. Proc Natl Acad Sci U S A. 2007;104:9673-8 pubmed
Diamandis P, Wildenhain J, Clarke I, Sacher A, Graham J, Bellows D, et al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007;3:268-73 pubmed
Shlomai A, Paran N, Shaul Y. PGC-1alpha controls hepatitis B virus through nutritional signals. Proc Natl Acad Sci U S A. 2006;103:16003-8 pubmed
Izumo M, Sato T, Straume M, Johnson C. Quantitative analyses of circadian gene expression in mammalian cell cultures. PLoS Comput Biol. 2006;2:e136 pubmed
Huang T, McDonough C, Abel T. Compartmentalized PKA signaling events are required for synaptic tagging and capture during hippocampal late-phase long-term potentiation. Eur J Cell Biol. 2006;85:635-42 pubmed
Pozuelo Rubio M, Campbell D, Morrice N, MacKintosh C. Phosphodiesterase 3A binds to 14-3-3 proteins in response to PMA-induced phosphorylation of Ser428. Biochem J. 2005;392:163-72 pubmed
Calloe K, Elmedyb P, Olesen S, Jorgensen N, Grunnet M. Hypoosmotic cell swelling as a novel mechanism for modulation of cloned HCN2 channels. Biophys J. 2005;89:2159-69 pubmed
Cherian Shaw M, Das R, Vandevoort C, Chaffin C. Regulation of steroidogenesis by p53 in macaque granulosa cells and H295R human adrenocortical cells. Endocrinology. 2004;145:5734-44 pubmed
Orlando E, Kolok A, Binzcik G, Gates J, Horton M, Lambright C, et al. Endocrine-disrupting effects of cattle feedlot effluent on an aquatic sentinel species, the fathead minnow. Environ Health Perspect. 2004;112:353-8 pubmed
Insel P, Ostrom R. Forskolin as a tool for examining adenylyl cyclase expression, regulation, and G protein signaling. Cell Mol Neurobiol. 2003;23:305-14 pubmed
Maurel C, Kado R, Guern J, Chrispeels M. Phosphorylation regulates the water channel activity of the seed-specific aquaporin alpha-TIP. EMBO J. 1995;14:3028-35 pubmed
Galli C, Meucci O, Scorziello A, Werge T, Calissano P, Schettini G. Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis. J Neurosci. 1995;15:1172-9 pubmed
Seamon K, Daly J, Metzger H, De Souza N, Reden J. Structure-activity relationships for activation of adenylate cyclase by the diterpene forskolin and its derivatives. J Med Chem. 1983;26:436-9 pubmed
Seamon K, Daly J. Forskolin: a unique diterpene activator of cyclic AMP-generating systems. J Cyclic Nucleotide Res. 1981;7:201-24 pubmed
Seamon K, Padgett W, Daly J. Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells. Proc Natl Acad Sci U S A. 1981;78:3363-7 pubmed
Watson E, Jacobson K. Forskolin activation of adenylate cyclase in mouse parotid membranes. Life Sci. 1986;39:693-7 pubmed
Defize J, Hunt R. Effect of hydrochloric acid and prostaglandins on pepsinogen synthesis and secretion in canine gastric chief cell monolayer cultures. Gut. 1989;30:774-81 pubmed
Miyamoto K, Sanae F, Koshiura R, Matsunaga T, Takagi K, Satake T, et al. Stimulatory and inhibitory effects of forskolin on adenylate cyclase in rat normal hepatocytes and hepatoma cells. J Pharmacobiodyn. 1989;12:87-93 pubmed
product information
Catalog Number :
F6886
Product Name :
Forskolin
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
from Coleus forskohlii, ≥98% (HPLC), powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA