Biggi S, Pancher M, Stincardini C, Luotti S, Massignan T, Dalle Vedove A, et al. Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface. J Neurochem. 2020;152:136-150 pubmed publisher

Li L, Zhao H, Chen B, Fan Z, Li N, Yue J, et al. FXR activation alleviates tacrolimus-induced post-transplant diabetes mellitus by regulating renal gluconeogenesis and glucose uptake. J Transl Med. 2019;17:418 pubmed publisher

Puri R, Cheng X, Lin M, Huang N, Sheng Z. Mul1 restrains Parkin-mediated mitophagy in mature neurons by maintaining ER-mitochondrial contacts. Nat Commun. 2019;10:3645 pubmed publisher

Rodrigues I, Pereira L, Lisboa J, Pereira C, Oliveira P, dos Santos N, et al. Involvement of Hsp90 and cyclophilins in intoxication by AIP56, a metalloprotease toxin from Photobacterium damselae subsp. piscicida. Sci Rep. 2019;9:9019 pubmed publisher

Burat B, Gonzalez J, Sauvage F, Aouad H, Arnion H, Pinault E, et al. Sum of peak intensities outperforms peak area integration in iTRAQ protein expression measurement by LC-MS/MS using a TripleTOF 5600+ platform. Biosci Rep. 2019;: pubmed publisher

Lai Y, Zhu B, Sun F, Luo D, Ma Y, Luo B, et al. Estrogen receptor α promotes Cav1.2 ubiquitination and degradation in neuronal cells and in APP/PS1 mice. Aging Cell. 2019;18:e12961 pubmed publisher

Liu P, Shah R, Li Y, Arora A, Ung P, Raman R, et al. An IRAK1-PIN1 signalling axis drives intrinsic tumour resistance to radiation therapy. Nat Cell Biol. 2019;21:203-213 pubmed publisher

Bodnar Broniarczyk M, Pawinski T, Kunicki P. Isotope-labeled versus analog internal standard in LC-MS/MS method for tacrolimus determination in human whole blood samples - A compensation of matrix effects. J Chromatogr B Analyt Technol Biomed Life Sci. 2019;1104:220-227 pubmed publisher

Jiang H, Zhang C, Tang Y, Zhao J, Wang T, Liu H, et al. The regulator of calcineurin 1 increases adenine nucleotide translocator 1 and leads to mitochondrial dysfunctions. J Neurochem. 2017;140:307-319 pubmed publisher

O Donnell J, Jackson J, Robinson M. Transient Oxygen/Glucose Deprivation Causes a Delayed Loss of Mitochondria and Increases Spontaneous Calcium Signaling in Astrocytic Processes. J Neurosci. 2016;36:7109-27 pubmed publisher

Jung J, Kang K, Kim J, Hong S, Park Y, Kim B. CXCR2 Inhibition in Human Pluripotent Stem Cells Induces Predominant Differentiation to Mesoderm and Endoderm Through Repression of mTOR, ?-Catenin, and hTERT Activities. Stem Cells Dev. 2016;25:1006-19 pubmed publisher

TenBroek E, Yunker L, Nies M, Bendele A. Randomized controlled studies on the efficacy of antiarthritic agents in inhibiting cartilage degeneration and pain associated with progression of osteoarthritis in the rat. Arthritis Res Ther. 2016;18:24 pubmed publisher

Becker L, Hallscheidt P, Schaefer S, Klein K, Grenacher L, Waldherr R, et al. A Single-center Experience on the Value of Pancreas Graft Biopsies and HLA Antibody Monitoring After Simultaneous Pancreas-Kidney Transplantation. Transplant Proc. 2015;47:2504-12 pubmed publisher

Argudo A, González de Aledo J, Alía P, Ramírez P, Serrano T, Fabregat J, et al. Liver Transplant Patient Carriers of Polymorphism Cyp3a5*1 Donors May Need More Doses of Tacrolimus From the First Month After Transplantation. Transplant Proc. 2015;47:2388-92 pubmed publisher

Kim H, Yang Y, Ko H, Kim G, Cho S, Seo Y, et al. Maintenance Therapy of Facial Seborrheic Dermatitis with 0.1% Tacrolimus Ointment. Ann Dermatol. 2015;27:523-30 pubmed publisher

Vollmers C, De Vlaminck I, Valantine H, Penland L, Luikart H, Strehl C, et al. Monitoring pharmacologically induced immunosuppression by immune repertoire sequencing to detect acute allograft rejection in heart transplant patients: a proof-of-concept diagnostic accuracy study. PLoS Med. 2015;12:e1001890 pubmed publisher

Kang H, Lee C, Kim J, Kwon J, Seo S, Han J, et al. Chlorella vulgaris Attenuates Dermatophagoides Farinae-Induced Atopic Dermatitis-Like Symptoms in NC/Nga Mice. Int J Mol Sci. 2015;16:21021-34 pubmed publisher

Lim E, Chin R, Nachbur U, Silke J, Jia Z, Angus P, et al. Effect of Immunosuppressive Agents on Hepatocyte Apoptosis Post-Liver Transplantation. PLoS ONE. 2015;10:e0138522 pubmed publisher

Koch M, Wiech T, Marget M, Peine S, Thude H, Achilles E, et al. De novo mTOR inhibitor-based immunosuppression in ABO-incompatible kidney transplantation. Clin Transplant. 2015;29:1021-8 pubmed publisher

Ruiz J, Herrero M, Bosó V, Megías J, Hervás D, Poveda J, et al. Impact of Single Nucleotide Polymorphisms (SNPs) on Immunosuppressive Therapy in Lung Transplantation. Int J Mol Sci. 2015;16:20168-82 pubmed publisher

Chen C, Merriman A, Savage J, Willer J, Wahlig T, Katsanis N, et al. Transient laminin beta 1a Induction Defines the Wound Epidermis during Zebrafish Fin Regeneration. PLoS Genet. 2015;11:e1005437 pubmed publisher

Zou X, Song B, Duan J, Hu Z, Cui Z, Gu C. Prolonged ischemia elicits acute allograft rejection involved in CXCR3 activation in rat kidney transplants. Transpl Immunol. 2015;33:103-9 pubmed publisher

Kim S, Lee S, Kim Y, Park S. Conversion of twice-daily to once-daily tacrolimus is safe in stable adult living donor liver transplant recipients. Hepatobiliary Pancreat Dis Int. 2015;14:374-9 pubmed

Meijers R, Litjens N, Hesselink D, Langerak A, Baan C, Betjes M. Primary Cytomegalovirus Infection Significantly Impacts Circulating T Cells in Kidney Transplant Recipients. Am J Transplant. 2015;15:3143-56 pubmed publisher

Gao L, Zhang C, Gao L, Liu Y, Su Y, Wang S, et al. Favorable outcome of haploidentical hematopoietic stem cell transplantation in Philadelphia chromosome-positive acute lymphoblastic leukemia: a multicenter study in Southwest China. J Hematol Oncol. 2015;8:90 pubmed publisher

Gallagher H, Sarwar G, Tse T, Sladden T, Hii E, Yerkovich S, et al. Erratic tacrolimus exposure, assessed using the standard deviation of trough blood levels, predicts chronic lung allograft dysfunction and survival. J Heart Lung Transplant. 2015;34:1442-8 pubmed publisher

Abbas K, Mubarak M, Zafar M, Aziz T, Abbas H, Muzaffar R, et al. Plasma cell-rich acute rejections in living-related kidney transplantation: a clinicopathological study of 50 cases. Clin Transplant. 2015;29:835-41 pubmed publisher

Lee Y, Song G. Relative efficacy and safety of tacrolimus, mycophenolate mofetil, and cyclophosphamide as induction therapy for lupus nephritis: a Bayesian network meta-analysis of randomized controlled trials. Lupus. 2015;24:1520-8 pubmed publisher

Kojima R, Yoshida T, Tasaki H, Umejima H, Maeda M, Higashi Y, et al. Release mechanisms of tacrolimus-loaded PLGA and PLA microspheres and immunosuppressive effects of the microspheres in a rat heart transplantation model. Int J Pharm. 2015;492:20-7 pubmed publisher

Unzu C, Melero I, Hervas Stubbs S, Sampedro A, Mancheno U, Morales Kastresana A, et al. Helper-dependent adenovirus achieve more efficient and persistent liver transgene expression in non-human primates under immunosuppression. Gene Ther. 2015;22:856-65 pubmed publisher

Matsuo H, Itoh H, Kitamura N, Kamikubo Y, Higuchi T, Shiga S, et al. Intravenous immunoglobulin enhances the killing activity and autophagy of neutrophils isolated from immunocompromised patients against multidrug-resistant bacteria. Biochem Biophys Res Commun. 2015;464:94-9 pubmed publisher

de Jonge H, Vanhove T, de Loor H, Verbeke K, Kuypers D. Progressive decline in tacrolimus clearance after renal transplantation is partially explained by decreasing CYP3A4 activity and increasing haematocrit. Br J Clin Pharmacol. 2015;80:548-59 pubmed publisher

Traitanon O, Mathew J, La Monica G, Xu L, Mas V, Gallon L. Differential Effects of Tacrolimus versus Sirolimus on the Proliferation, Activation and Differentiation of Human B Cells. PLoS ONE. 2015;10:e0129658 pubmed publisher

Margaillan G, Rouleau M, Klein K, Fallon J, Caron P, Villeneuve L, et al. Multiplexed Targeted Quantitative Proteomics Predicts Hepatic Glucuronidation Potential. Drug Metab Dispos. 2015;43:1331-5 pubmed publisher

Menotta M, Biagiotti S, Streppa L, Rossi L, Magnani M. Label-free quantification of Tacrolimus in biological samples by atomic force microscopy. Anal Chim Acta. 2015;884:90-6 pubmed publisher

Kloster Jensen K, Vethe N, Bremer S, Abadpour S, Korsgren O, Foss A, et al. Intracellular sirolimus concentration is reduced by tacrolimus in human pancreatic islets in vitro. Transpl Int. 2015;28:1152-61 pubmed publisher

Nagib A, Abbas M, Abu Elmagd M, Denewar A, Neamatalla A, Refaie A, et al. Long-term study of steroid avoidance in renal transplant patients: a single-center experience. Transplant Proc. 2015;47:1099-104 pubmed publisher

Yagisawa T, Omoto K, Shimizu T, Ishida H, Tanabe K. Arteriosclerosis in zero-time biopsy is a risk factor for tacrolimus-induced chronic nephrotoxicity. Nephrology (Carlton). 2015;20 Suppl 2:51-7 pubmed publisher

Harada S, Ushigome H, Nishimura A, Nakao T, Nakamura T, Koshino K, et al. Histological reversibility of diabetic nephropathy after kidney transplantation from diabetic donor to non-diabetic recipient. Nephrology (Carlton). 2015;20 Suppl 2:40-4 pubmed publisher

Iwai H, Shimada H, Nishimura S, Kobayashi Y, Itakura G, Hori K, et al. Allogeneic Neural Stem/Progenitor Cells Derived From Embryonic Stem Cells Promote Functional Recovery After Transplantation Into Injured Spinal Cord of Nonhuman Primates. Stem Cells Transl Med. 2015;4:708-19 pubmed publisher

Spolidorio L, Herrera B, Coimbra L, de Andrade C, Spolidorio D, Rossa Junior C, et al. The long-term administration of calcineurin inhibitors decreases antioxidant enzyme activity in the rat parotid and submandibular salivary glands. Life Sci. 2015;134:1-8 pubmed publisher

Söderlund C, Rådegran G. Safety and efficacy of the switch to generic mycophenolate mofetil and tacrolimus in heart transplant patients. Clin Transplant. 2015;29:619-28 pubmed publisher

van Boekel G, Donders A, Hoogtanders K, Havenith T, Hilbrands L, Aarnoutse R. Limited sampling strategy for prolonged-release tacrolimus in renal transplant patients by use of the dried blood spot technique. Eur J Clin Pharmacol. 2015;71:811-6 pubmed publisher

Mistry N, Desai J, Thakkar H. Formulation and evaluation of tacrolimus-loaded galactosylated Poly(lactic-co-glycolic acid) nanoparticles for liver targeting. J Pharm Pharmacol. 2015;67:1337-48 pubmed publisher

Nakamura T, Nakao T, Yoshimura N, Ashihara E. Rapamycin Prolongs Cardiac Allograft Survival in a Mouse Model by Inducing Myeloid-Derived Suppressor Cells. Am J Transplant. 2015;15:2364-77 pubmed publisher

Wu J, Li H, Li M. Effects of baicalin cream in two mouse models: 2,4-dinitrofluorobenzene-induced contact hypersensitivity and mouse tail test for psoriasis. Int J Clin Exp Med. 2015;8:2128-37 pubmed

Vrzal R, Zenata O, Bachleda P, Dvorak Z. The effects of drugs with immunosuppressive or immunomodulatory activities on xenobiotics-metabolizing enzymes expression in primary human hepatocytes. Toxicol In Vitro. 2015;29:1088-99 pubmed publisher

Hiraoka S, Kato J, Moritou Y, Takei D, Inokuchi T, Nakarai A, et al. The earliest trough concentration predicts the dose of tacrolimus required for remission induction therapy in ulcerative colitis patients. BMC Gastroenterol. 2015;15:53 pubmed publisher

Nagaya M, Arai Y, Matsunari H, Honda M, Nakano K, Maehara M, et al. A new system to evaluate the influence of immunosuppressive drugs on pancreatic islets using epigenetic analysis in a 3-dimensional culture. Pancreas. 2015;44:778-85 pubmed publisher

Meyer C, Walker J, Dewane J, Engelmann F, Laub W, Pillai S, et al. Impact of irradiation and immunosuppressive agents on immune system homeostasis in rhesus macaques. Clin Exp Immunol. 2015;181:491-510 pubmed publisher

Chen Y, Zeng L, Xiong W, Song M, Du H, Wang Y, et al. Anti-duck virus hepatitis mechanisms of Bush Sophora Root polysaccharide and its sulfate verified by intervention experiments. Virus Res. 2015;204:58-67 pubmed publisher

Bifano M, Adamczyk R, Hwang C, Kandoussi H, Marion A, Bertz R. An open-label investigation into drug-drug interactions between multiple doses of daclatasvir and single-dose cyclosporine or tacrolimus in healthy subjects. Clin Drug Investig. 2015;35:281-9 pubmed publisher

Görzer I, Jaksch P, Kundi M, Seitz T, Klepetko W, Puchhammer Stöckl E. Pre-transplant plasma Torque Teno virus load and increase dynamics after lung transplantation. PLoS ONE. 2015;10:e0122975 pubmed publisher

Elgendy H, El Moghazy W, Nafady Hego H, Uemoto S. Outcome of critically-ill children after living-donor liver transplant. Exp Clin Transplant. 2015;13 Suppl 1:100-7 pubmed

Ganetsky A, Miano T, Hughes M, Vonderheide R, Porter D, Reshef R. Lack of a significant pharmacokinetic interaction between maraviroc and tacrolimus in allogeneic HSCT recipients. J Antimicrob Chemother. 2015;70:2078-83 pubmed publisher

Chapron B, Risler L, Phillips B, Collins C, Thummel K, Shen D. Reversible, time-dependent inhibition of CYP3A-mediated metabolism of midazolam and tacrolimus by telaprevir in human liver microsomes. J Pharm Pharm Sci. 2015;18:101-11 pubmed

Nashan B, Schemmer P, Braun F, Dworak M, Wimmer P, Schlitt H. Evaluating the efficacy, safety and evolution of renal function with early initiation of everolimus-facilitated tacrolimus reduction in de novo liver transplant recipients: Study protocol for a randomized controlled trial. Trials. 2015;16:118 pubmed publisher

Rosso Fernández C, Garnacho Montero J, Antonelli M, Dimopoulos G, Cisneros J. Safety and efficacy of colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia as part of a macro-project funded by the Seventh Framework Program of the European Commission studying off-patent antibiotics: study protoc. Trials. 2015;16:102 pubmed publisher

Zhu L, Yang J, Zhang Y, Jing Y, Zhang Y, Li G. Effects of CYP3A5 genotypes, ABCB1 C3435T and G2677T/A polymorphism on pharmacokinetics of Tacrolimus in Chinese adult liver transplant patients. Xenobiotica. 2015;45:840-6 pubmed publisher

Xie X, Li J, Wang H, Li H, Liu J, Fu Q, et al. Associations of UDP-glucuronosyltransferases polymorphisms with mycophenolate mofetil pharmacokinetics in Chinese renal transplant patients. Acta Pharmacol Sin. 2015;36:644-50 pubmed publisher

Naito T, Mino Y, Aoki Y, Hirano K, Shimoyama K, Ogawa N, et al. ABCB1 genetic variant and its associated tacrolimus pharmacokinetics affect renal function in patients with rheumatoid arthritis. Clin Chim Acta. 2015;445:79-84 pubmed publisher

Seyhun Y, Ciftci H, Kekik C, Karadeniz M, Tefik T, Nane I, et al. Genetic association of interleukin-2, interleukin-4, interleukin-6, transforming growth factor-β, tumour necrosis factor-α and blood concentrations of calcineurin inhibitors in Turkish renal transplant patients. Int J Immunogenet. 2015;42:147-60 pubmed publisher

Bonadio I, Colle I, Geerts A, Smeets P, Berardi G, Praet M, et al. Liver transplantation for hepatocellular carcinoma comparing the Milan, UCSF, and Asan criteria: long-term follow-up of a Western single institutional experience. Clin Transplant. 2015;29:425-33 pubmed publisher

Nakazato R, Takarada T, Ikeno S, Nakamura S, Kutsukake T, Hinoi E, et al. Upregulation of Runt-Related Transcription Factor-2 Through CCAAT Enhancer Binding Protein-β Signaling Pathway in Microglial BV-2 Cells Exposed to ATP. J Cell Physiol. 2015;230:2510-21 pubmed publisher

Jung K, Lee Y, Ryu Y, Kim J, Kim H, Kim B, et al. Effects of topically applied rapamycin and mycophenolic acid on TNCB-induced atopic dermatitis-like skin lesions in NC/Nga mice. Int Immunopharmacol. 2015;26:432-8 pubmed publisher

Tavira B, Gómez J, Diaz Corte C, Suarez B, Coronel D, Arias M, et al. ABCB1 (MDR-1) pharmacogenetics of tacrolimus in renal transplanted patients: a Next Generation Sequencing approach. Clin Chem Lab Med. 2015;53:1515-9 pubmed publisher

Tong M, Chai H, Liu W, Chen C, Fu M, Lin Y, et al. Prevalence of hypertension after living-donor liver transplantation: a prospective study. Transplant Proc. 2015;47:445-50 pubmed publisher

Lisboa L, Egli A, Fairbanks J, O Shea D, Manuel O, Husain S, et al. CCL8 and the Immune Control of Cytomegalovirus in Organ Transplant Recipients. Am J Transplant. 2015;15:1882-92 pubmed publisher

Rahman Z, Bykadi S, Siddiqui A, Khan M. Comparison of X-ray powder diffraction and solid-state nuclear magnetic resonance in estimating crystalline fraction of tacrolimus in sustained-release amorphous solid dispersion and development of discriminating dissolution method. J Pharm Sci. 2015;104:1777-86 pubmed publisher

Guo H, Zhang H, Lu L, Ezzelarab M, Thomson A. Generation, cryopreservation, function and in vivo persistence of ex vivo expanded cynomolgus monkey regulatory T cells. Cell Immunol. 2015;295:19-28 pubmed publisher

Jóźwiak Bębenista M, Kowalczyk E, Nowak J. The cyclic AMP effects and neuroprotective activities of PACAP and VIP in cultured astrocytes and neurons exposed to oxygen-glucose deprivation. Pharmacol Rep. 2015;67:332-8 pubmed publisher

Velickovic Radovanovic R, Jankovic S, Milovanovic J, Catić Đorđević A, Spasić A, Stefanovic N, et al. Variability of mycophenolic acid elimination in the renal transplant recipients – population pharmacokinetic approach. Ren Fail. 2015;37:652-8 pubmed publisher

Trunecka P, Klempnauer J, Bechstein W, Pirenne J, Friman S, Zhao A, et al. Renal Function in De Novo Liver Transplant Recipients Receiving Different Prolonged-Release Tacrolimus Regimens-The DIAMOND Study. Am J Transplant. 2015;15:1843-54 pubmed publisher

Espitalier F, Durand N, Rémy S, Corre P, Sourice S, Pilet P, et al. Development of a cyclosporin-A-induced immune tolerant rat model to test marrow allograft cell type effects on bone repair. Calcif Tissue Int. 2015;96:430-7 pubmed publisher

Kwun J, Page E, Hong J, GIBBY A, Yoon J, Farris A, et al. Neutralizing BAFF/APRIL with atacicept prevents early DSA formation and AMR development in T cell depletion induced nonhuman primate AMR model. Am J Transplant. 2015;15:815-22 pubmed publisher

Stefanović N, Cvetković T, Jevtović Stoimenov T, Zvezdanović Čelebić L, Stojanović D, Ignjatović A, et al. Potential role of tacrolimus in erythrocytes' antioxidative capacity in long-term period after renal transplantation. Eur J Pharm Sci. 2015;70:132-9 pubmed publisher

Park J, Joo C, Chung S. Comparative study of tacrolimus and bevacizumab on corneal neovascularization in rabbits. Cornea. 2015;34:449-55 pubmed publisher

Margaillan G, Rouleau M, Fallon J, Caron P, Villeneuve L, Turcotte V, et al. Quantitative profiling of human renal UDP-glucuronosyltransferases and glucuronidation activity: a comparison of normal and tumoral kidney tissues. Drug Metab Dispos. 2015;43:611-9 pubmed publisher

Mizokami D, Araki K, Tanaka N, Suzuki H, Tomifuji M, Yamashita T, et al. Tacrolimus prevents laryngotracheal stenosis in an acute-injury rat model. Laryngoscope. 2015;125:E210-5 pubmed publisher

Van Driest S, Webber S. Pharmacogenomics: personalizing pediatric heart transplantation. Circulation. 2015;131:503-12 pubmed publisher

Chen Q, Li J, Zuo S, Zhang Y, Jia S, Yuan H, et al. Tacrolimus decreases insulin sensitivity without reducing fasting insulin concentration: a 2-year follow-up study in kidney transplant recipients. Ren Fail. 2015;37:601-6 pubmed publisher

Aouam K, Chadli Z, Hammouda M, Fredj N, Aloui S, May M, et al. Development of Limited Sampling Strategies for the Estimation of Tacrolimus Area Under the Curve in Adult Kidney Transplant Recipients According to the Posttransplantation Time. Ther Drug Monit. 2015;37:524-30 pubmed publisher

van den Hoogen M, Kamburova E, Baas M, Steenbergen E, Florquin S, M Koenen H, et al. Rituximab as induction therapy after renal transplantation: a randomized, double-blind, placebo-controlled study of efficacy and safety. Am J Transplant. 2015;15:407-16 pubmed publisher

Oda K, Yamano K, Otsuka Y. In vitro-in vivo extrapolations to evaluate the effect of concomitant drugs on tacrolimus (FK506) exposure. Biopharm Drug Dispos. 2015;36:265-74 pubmed publisher

Niioka T, Kagaya H, Saito M, Inoue T, Numakura K, Habuchi T, et al. Capability of utilizing CYP3A5 polymorphisms to predict therapeutic dosage of tacrolimus at early stage post-renal transplantation. Int J Mol Sci. 2015;16:1840-54 pubmed publisher

Rudolph E, Finger E, Chandolias N, Kandaswamy R, Sutherland D, Dunn T. Outcomes of pancreas retransplantation. Transplantation. 2015;99:367-74 pubmed publisher

Clift D, Thorn R, Passarelli E, Kapoor M, LoPiccolo M, Richendrfer H, et al. Effects of embryonic cyclosporine exposures on brain development and behavior. Behav Brain Res. 2015;282:117-24 pubmed publisher

Knops N, van den Heuvel L, Masereeuw R, Bongaers I, de Loor H, Levtchenko E, et al. The functional implications of common genetic variation in CYP3A5 and ABCB1 in human proximal tubule cells. Mol Pharm. 2015;12:758-68 pubmed publisher

Liu X, Li J, Fu Q, Liu S, Zhang Y, Wang X, et al. Associations of HSD11B1 polymorphisms with tacrolimus concentrations in Chinese renal transplant recipients with prednisone combined therapy. Drug Metab Dispos. 2015;43:455-8 pubmed publisher

COTTON D. Celebrating the ACP centennial: from the Annals archive. Ann Intern Med. 2015;162:70 pubmed publisher

Shi R, El Gierari E, Manicke N, Faix J. Rapid measurement of tacrolimus in whole blood by paper spray-tandem mass spectrometry (PS-MS/MS). Clin Chim Acta. 2015;441:99-104 pubmed publisher

Cai W, Ye C, Sun X, Qin K, Qin Y, Zhao D, et al. Limited sampling strategy for predicting area under the concentration-time curve for mycophenolic Acid in Chinese adults receiving mycophenolate mofetil and tacrolimus early after renal transplantation. Ther Drug Monit. 2015;37:304-10 pubmed publisher

Morishima Y, Kashiwase K, Matsuo K, Azuma F, Morishima S, Onizuka M, et al. Biological significance of HLA locus matching in unrelated donor bone marrow transplantation. Blood. 2015;125:1189-97 pubmed publisher

Tornatore K, Meaney C, Wilding G, Chang S, Gundroo A, Cooper L, et al. Influence of sex and race on mycophenolic acid pharmacokinetics in stable African American and Caucasian renal transplant recipients. Clin Pharmacokinet. 2015;54:423-34 pubmed publisher

Lü Y, Su Q, Wu K, Ren Y, Li L, Zhou T, et al. A population pharmacokinetic study of tacrolimus in healthy Chinese volunteers and liver transplant patients. Acta Pharmacol Sin. 2015;36:281-8 pubmed publisher

Ferreiro A, Vazquez Millán M, López F, Gutiérrez M, Diaz S, Patiño M. Everolimus-based immunosuppression in patients with hepatocellular carcinoma at high risk of recurrence after liver transplantation: a case series. Transplant Proc. 2014;46:3496-501 pubmed publisher

Kleist C, Sandra Petrescu F, Jiga L, Dittmar L, Mohr E, Greil J, et al. Generation of suppressive blood cells for control of allograft rejection. Clin Sci (Lond). 2015;128:593-607 pubmed publisher

Lin B, Chen M, Fan S, Chuck R, Zhou S. Effect of 0.025% FK-506 eyedrops on botulinum toxin B-induced mouse dry eye. Invest Ophthalmol Vis Sci. 2014;56:45-53 pubmed publisher

Fernandes M, Caldas H, Toloni L, Baptista M, Fernandes I, Abbud Filho M. Supplementation with omega-3 polyunsaturated fatty acids and experimental tacrolimus-induced nephrotoxicity. Exp Clin Transplant. 2014;12:522-7 pubmed

Poirier N, Dilek N, Mary C, Ville S, Coulon F, Branchereau J, et al. FR104, an antagonist anti-CD28 monovalent fab' antibody, prevents alloimmunization and allows calcineurin inhibitor minimization in nonhuman primate renal allograft. Am J Transplant. 2015;15:88-100 pubmed publisher

Xing J, Zhang X, Fan J, Shen B, Men T, Wang J. Association between interleukin-18 promoter variants and tacrolimus pharmacokinetics in Chinese renal transplant patients. Eur J Clin Pharmacol. 2015;71:191-8 pubmed publisher

Aelvoet S, Ibrahimi A, Macchi F, Gijsbers R, Van den Haute C, Debyser Z, et al. Noninvasive bioluminescence imaging of α-synuclein oligomerization in mouse brain using split firefly luciferase reporters. J Neurosci. 2014;34:16518-32 pubmed publisher

Imai D, Ikegami T, Toshima T, Yoshizumi T, Yamashita Y, Ninomiya M, et al. Preemptive thoracic drainage to eradicate postoperative pulmonary complications after living donor liver transplantation. J Am Coll Surg. 2014;219:1134-42.e2 pubmed publisher

Arai S, Arora M, Wang T, Spellman S, He W, Couriel D, et al. Increasing incidence of chronic graft-versus-host disease in allogeneic transplantation: a report from the Center for International Blood and Marrow Transplant Research. Biol Blood Marrow Transplant. 2015;21:266-74 pubmed publisher

Johannesson L, Kvarnström N, Mölne J, Dahm Kähler P, Enskog A, Diaz Garcia C, et al. Uterus transplantation trial: 1-year outcome. Fertil Steril. 2015;103:199-204 pubmed publisher

Díaz García C, Johannesson L, Shao R, Bilig H, Brännström M. Pregnancy after allogeneic uterus transplantation in the rat: perinatal outcome and growth trajectory. Fertil Steril. 2014;102:1545-52.e1 pubmed publisher

Biancofiore G, Bindi M, Miccoli M, Cerutti E, Lavezzo B, Pucci L, et al. Intravenous fenoldopam for early acute kidney injury after liver transplantation. J Anesth. 2015;29:426-432 pubmed publisher

Siponen M, Kullaa A, Nieminen P, Salo T, Pasonen Seppänen S. Altered expression of hyaluronan, HAS1-2, and HYAL1-2 in oral lichen planus. J Oral Pathol Med. 2015;44:401-9 pubmed publisher

Fukuda A, Imadome K, Sakamoto S, Shigeta T, Uchida H, Matsunami M, et al. Evaluation of the immune function assay in pediatric living donor liver transplantation. Pediatr Transplant. 2015;19:144-52 pubmed publisher

Leboeuf C, Roser Schilder J, Lambotin M, Durand S, Wu T, Fauvelle C, et al. Prevention of hepatitis C virus infection by adoptive allogeneic immunotherapy using suicide gene-modified lymphocytes: an in vitro proof-of-concept. Gene Ther. 2015;22:172-80 pubmed publisher

Caiazzo R, Vantyghem M, Raverdi V, Bonner C, Gmyr V, Defrance F, et al. Impact of Procedure-Related Complications on Long-term Islet Transplantation Outcome. Transplantation. 2015;99:979-84 pubmed publisher

. Summaries for patients. Multitarget therapy for induction treatment of lupus nephritis. Ann Intern Med. 2015;162:I24 pubmed publisher

Liu Z, Zhang H, Liu Z, Xing C, Fu P, Ni Z, et al. Multitarget therapy for induction treatment of lupus nephritis: a randomized trial. Ann Intern Med. 2015;162:18-26 pubmed publisher

Nowosiad Magda M, Myślak M, Roszkowska P, Borowiec Chłopek Z, Urasińska E, Różański J, et al. Analysis of specificity of anti-human leukocyte antigen antibodies in kidney recipients in reference to clinical outcome. Transplant Proc. 2014;46:2606-12 pubmed publisher

Li H, Chen Z, Zhang C, Gao Y, Zhang X, Sun S. Resistance reversal induced by a combination of fluconazole and tacrolimus (FK506) in Candida glabrata. J Med Microbiol. 2015;64:44-52 pubmed publisher

Su J, Kelly R, Grogan T, Elashoff D, Alejos J. Extracorporeal membrane oxygenation support after pediatric orthotopic heart transplantation. Pediatr Transplant. 2015;19:68-75 pubmed publisher

Kuypers D, de Loor H, Naesens M, Coopmans T, de Jonge H. Combined effects of CYP3A5*1, POR*28, and CYP3A4*22 single nucleotide polymorphisms on early concentration-controlled tacrolimus exposure in de-novo renal recipients. Pharmacogenet Genomics. 2014;24:597-606 pubmed publisher

Ribero S, Stieger M, Quaglino P, Hongang T, Bornstein M, Naldi L, et al. Efficacy of topical tacrolimus for oral lichen planus: real-life experience in a retrospective cohort of patients with a review of the literature. J Eur Acad Dermatol Venereol. 2015;29:1107-13 pubmed publisher

Brännström M, Johannesson L, Bokström H, Kvarnström N, Mölne J, Dahm Kähler P, et al. Livebirth after uterus transplantation. Lancet. 2015;385:607-616 pubmed publisher

Carpio V, Noronha I, Martins H, Jobim L, Gil B, Külzer A, et al. Expression patterns of B cells in acute kidney transplant rejection. Exp Clin Transplant. 2014;12:405-14 pubmed

Schaap M, Wackers P, Zwart E, Huijskens I, Jonker M, Hendriks G, et al. A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens. Arch Toxicol. 2015;89:2413-27 pubmed publisher

Shuker N, Cadogan M, van Gelder T, Roodnat J, Kho M, Weimar W, et al. Conversion from twice-daily to once-daily tacrolimus does not reduce intrapatient variability in tacrolimus exposure. Ther Drug Monit. 2015;37:262-9 pubmed publisher

Yamazoe K, Yamazoe K, Yamaguchi T, Omoto M, Shimazaki J. Efficacy and safety of systemic tacrolimus in high-risk penetrating keratoplasty after graft failure with systemic cyclosporine. Cornea. 2014;33:1157-63 pubmed publisher

Orban J, Quintard H, Cassuto E, Jambou P, Samat Long C, Ichai C. Effect of N-acetylcysteine pretreatment of deceased organ donors on renal allograft function: a randomized controlled trial. Transplantation. 2015;99:746-53 pubmed publisher

Nath P, Dong G, Braiman A, Isakov N. Immunophilins control T lymphocyte adhesion and migration by regulating CrkII binding to C3G. J Immunol. 2014;193:3966-77 pubmed publisher

Hayashi C, Ito M, Ito R, Murakumo A, Yamamoto N, Hiramatsu N, et al. Effects of edaravone, a radical scavenger, on hepatocyte transplantation. J Hepatobiliary Pancreat Sci. 2014;21:919-24 pubmed publisher

Ding L, Heremans Y, Pipeleers D, Ling Z, Heimberg H, Gysemans C, et al. Clinical Immunosuppressants Inhibit Inflammatory, Proliferative, and Reprogramming Potential, But Not Angiogenesis of Human Pancreatic Duct Cells. Cell Transplant. 2015;24:1585-98 pubmed publisher

Goldberg N, Lyu T, Moshier E, Godbold J, Jabs D. Success with single-agent immunosuppression for multifocal choroidopathies. Am J Ophthalmol. 2014;158:1310-7 pubmed publisher

Jacobo Cabral C, García Roca P, Reyes H, Lozada Rojas L, Cruz Antonio L, Medeiros M, et al. Limustin®, a non-innovator tacrolimus formulation, yields reduced drug exposure in pediatric renal transplant recipients. Pediatr Transplant. 2014;18:706-13 pubmed publisher

Sung Y, Lee A, Kim H. The Gardenia jasminoides extract and its constituent, geniposide, elicit anti-allergic effects on atopic dermatitis by inhibiting histamine in vitro and in vivo. J Ethnopharmacol. 2014;156:33-40 pubmed publisher

Robertsen I, Asberg A, Ingerø A, Vethe N, Bremer S, Bergan S, et al. Use of generic tacrolimus in elderly renal transplant recipients: precaution is needed. Transplantation. 2015;99:528-32 pubmed publisher

Dannhorn E, Cheung M, Rodrigues S, Cooper H, Thorburn D, Patch D, et al. De novo use of generic tacrolimus in liver transplantation - a single center experience with one-yr follow-up. Clin Transplant. 2014;28:1349-57 pubmed publisher

Ott M, Litzenburger U, Rauschenbach K, Bunse L, Ochs K, Sahm F, et al. Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway. Glia. 2015;63:78-90 pubmed publisher

Huang H, Wang X, Ding X, Xu Q, Hwang S, Wang F, et al. Effect and mechanism of tacrolimus on melanogenesis on A375 human melanoma cells. Chin Med J (Engl). 2014;127:2966-71 pubmed

Dall Agnol D, Hauschildt A, Lima M, Corá L, Teixeira M, Américo M. Effects of immunosuppressive drugs on gastrointestinal transit of rats: effects of tacrolimus, cyclosporine, and prednisone. Transplant Proc. 2014;46:1872-4 pubmed publisher

Thorat A, Chou H, Lee C, Soong R, Wu T, Cheng C, et al. Effects of converting tacrolimus formulation from twice-daily to once-daily in liver transplantation recipients. Biomed Res Int. 2014;2014:265658 pubmed publisher

Dipchand A, White M, Manlhiot C, Pollock BarZiv S, Allain Rooney T, West L, et al. Myocyte growth, repair, and oxidative stress following pediatric heart transplantation. Pediatr Transplant. 2014;18:764-70 pubmed publisher

Pandey S, Mahato P, Bhattacharyya S. Metabotropic glutamate receptor 1 recycles to the cell surface in protein phosphatase 2A-dependent manner in non-neuronal and neuronal cell lines. J Neurochem. 2014;131:602-14 pubmed publisher

Grossman J, Cuellar Rodríguez J, Gea Banacloche J, Zerbe C, Calvo K, Hughes T, et al. Nonmyeloablative allogeneic hematopoietic stem cell transplantation for GATA2 deficiency. Biol Blood Marrow Transplant. 2014;20:1940-8 pubmed publisher

Hoerning A, Wilde B, Wang J, Tebbe B, Jing L, Wang X, et al. Pharmacodynamic monitoring of mammalian target of rapamycin inhibition by phosphoflow cytometric determination of p70S6 kinase activity. Transplantation. 2015;99:210-9 pubmed publisher

Wang B, Yang S, Hu J, Li Y. Multifaceted interaction of the traditional Chinese medicinal herb Schisandra chinensis with cytochrome P450-mediated drug metabolism in rats. J Ethnopharmacol. 2014;155:1473-82 pubmed publisher

Stevens R, Foster K, Miles C, Lane J, Kalil A, Florescu D, et al. A randomized 2×2 factorial trial, part 1: single-dose rabbit antithymocyte globulin induction may improve renal transplantation outcomes. Transplantation. 2015;99:197-209 pubmed publisher

Cisneros Barroso E, Yance Chávez T, Kito A, Sugiura R, Gómez Hierro A, Giménez Zaragoza D, et al. Negative feedback regulation of calcineurin-dependent Prz1 transcription factor by the CaMKK-CaMK1 axis in fission yeast. Nucleic Acids Res. 2014;42:9573-87 pubmed publisher

Kim H, Ryu H, Kim J, Kim Y, Lee H, Jung J, et al. Validation of cyclooxygenase-2 as a direct anti-inflammatory target of 4-O-methylhonokiol in zymosan-induced animal models. Arch Pharm Res. 2015;38:813-25 pubmed publisher

Oda K, Yamano K. Effect of telaprevir on the metabolism and hepatic uptake of tacrolimus (FK506). Biopharm Drug Dispos. 2014;35:501-12 pubmed publisher

Wannhoff A, Weiss K, Schemmer P, Stremmel W, Gotthardt D. Increased levels of rivaroxaban in patients after liver transplantation treated with cyclosporine A. Transplantation. 2014;98:e12-3 pubmed publisher

Rostaing L, Christiaans M, Kovarik J, Pascual J. The pharmacokinetics of everolimus in de novo kidney transplant patients receiving tacrolimus: an analysis from the randomized ASSET study. Ann Transplant. 2014;19:337-45 pubmed publisher

Friedrich R, Dimer F, Guterres S, Beck R, Pohlmann A. Nanoencapsulation of tacrolimus in lipid-core nanocapsules showed similar immunosuppressive activity after oral and intraperitoneal administrations. J Biomed Nanotechnol. 2014;10:1599-609 pubmed

Tapirdamaz O, Hesselink D, El Bouazzaoui S, Azimpour M, Hansen B, van der Laan L, et al. Genetic variance in ABCB1 and CYP3A5 does not contribute toward the development of chronic kidney disease after liver transplantation. Pharmacogenet Genomics. 2014;24:427-35 pubmed publisher

Ram B, Ramakrishna G. Endoplasmic reticulum vacuolation and unfolded protein response leading to paraptosis like cell death in cyclosporine A treated cancer cervix cells is mediated by cyclophilin B inhibition. Biochim Biophys Acta. 2014;1843:2497-512 pubmed publisher

Jannot M, Masson I, Alamartine E, Mariat C. Early conversion from twice-daily tacrolimus to once-daily extended formulation in renal transplant patients before hospital discharge. Ann Transplant. 2014;19:320-4 pubmed publisher

Yap D, Ma M, Mok M, Kwan L, Chan G, Chan T. Long-term data on tacrolimus treatment in lupus nephritis. Rheumatology (Oxford). 2014;53:2232-7 pubmed publisher

Yerly P, Rotman S, Nobile A, Aubert V, Tozzi P, Yarol N, et al. Time-dependent specificity of immunopathologic (C4d-CD68) and histologic criteria of antibody-mediated rejection for donor-specific antibodies and allograft dysfunction in heart transplantation. Transplantation. 2015;99:586-93 pubmed publisher

Welberry Smith M, Baker R. The author's reply. Transplantation. 2014;98:e2-3 pubmed publisher

Sureshkumar K, Chopra B. In search of an optimal induction agent in kidney transplantation. Transplantation. 2014;98:e1-2 pubmed publisher

Kim K, Chung B, Kim B, Cho M, Yang C. The effect of mammalian target of rapamycin inhibition on T helper type 17 and regulatory T cell differentiation in vitro and in vivo in kidney transplant recipients. Immunology. 2015;144:68-78 pubmed publisher

Sharanek A, Azzi P, Al Attrache H, Savary C, Humbert L, Rainteau D, et al. Different dose-dependent mechanisms are involved in early cyclosporine a-induced cholestatic effects in hepaRG cells. Toxicol Sci. 2014;141:244-53 pubmed publisher

Singla A, Gurram R, Chauhan A, Khatri N, Vohra R, Jolly R, et al. Cerulomycin Caerulomycin [corrected] A: a potent novel immunosuppressive agent. Transplantation. 2014;97:e57-9 pubmed

Kasutani K, Fujii E, Ohyama S, Adachi H, Hasegawa M, Kitamura H, et al. Anti-IL-31 receptor antibody is shown to be a potential therapeutic option for treating itch and dermatitis in mice. Br J Pharmacol. 2014;171:5049-58 pubmed publisher

Terada Y, Ogura J, Tsujimoto T, Kuwayama K, Koizumi T, Sasaki S, et al. Intestinal P-glycoprotein expression is multimodally regulated by intestinal ischemia-reperfusion. J Pharm Pharm Sci. 2014;17:266-76 pubmed

Kurzawski M, Malinowski D, Dziewanowski K, Drozdzik M. Impact of PPARA and POR polymorphisms on tacrolimus pharmacokinetics and new-onset diabetes in kidney transplant recipients. Pharmacogenet Genomics. 2014;24:397-400 pubmed publisher

Uesugi M, Kikuchi M, Shinke H, Omura T, Yonezawa A, Matsubara K, et al. Impact of cytochrome P450 3A5 polymorphism in graft livers on the frequency of acute cellular rejection in living-donor liver transplantation. Pharmacogenet Genomics. 2014;24:356-66 pubmed publisher

Marits P, Wikstrom A, Popadic D, Winqvist O, Thunberg S. Evaluation of T and B lymphocyte function in clinical practice using a flow cytometry based proliferation assay. Clin Immunol. 2014;153:332-42 pubmed publisher

Chen S, Zhou H, Byun H, Chen H, Pan H. Casein kinase II regulates N-methyl-D-aspartate receptor activity in spinal cords and pain hypersensitivity induced by nerve injury. J Pharmacol Exp Ther. 2014;350:301-12 pubmed publisher

Von Visger J, Gunay Y, Andreoni K, Bhatt U, Nori U, Pesavento T, et al. The risk of recurrent IgA nephropathy in a steroid-free protocol and other modifying immunosuppression. Clin Transplant. 2014;28:845-54 pubmed publisher

Harada N, Inada N, Ishimori A, Shoji J, Sawa M. [Follow-up study on patients with vernal keratoconjunctivitis undergoing topical 0.1% tacrolimus treatment]. Nippon Ganka Gakkai Zasshi. 2014;118:378-84 pubmed

Fukushima D, Sato K, Kawagishi N, Ohuchi N, Satomi S. Epstein-Barr virus--associated posttransplantation lymphoproliferative disorder with tacrolimus metabolism deterioration in infants after living-donor liver transplantation. Transplantation. 2015;99:114-9 pubmed publisher

Gujadhur A, Thomson N, Aung A, McLean C, Menahem S. CMV sinusitis in a HIV-negative renal transplant recipient. Transplantation. 2014;97:e55-7 pubmed publisher

Lim S, Doh K, Jin L, Heo S, Zheng Y, Bae S, et al. Combined treatment of tacrolimus and everolimus increases oxidative stress by pharmacological interactions. Transplantation. 2014;98:22-8 pubmed publisher

Stifft F, Vanmolkot F, Scheffers I, Van Bortel L, Neef C, Christiaans M. Rectal and sublingual administration of tacrolimus: a single-dose pharmacokinetic study in healthy volunteers. Br J Clin Pharmacol. 2014;78:996-1004 pubmed publisher

Gibbs B, Yasinska I, Calzolai L, Gilliland D, Sumbayev V. Highly specific targeting of human leukocytes using gold nanoparticle-based biologically active conjugates. J Biomed Nanotechnol. 2014;10:1259-66 pubmed

Gillard P, Rustandi M, Efendi A, Lee D, Ling Z, Hilbrands R, et al. Early alteration of kidney function in nonuremic type 1 diabetic islet transplant recipients under tacrolimus-mycophenolate therapy. Transplantation. 2014;98:451-7 pubmed publisher

Xu C, Niu Y, Liu X, Teng Y, Li C, Wang H, et al. Tacrolimus reversibly reduces insulin secretion, induces insulin resistance, and causes islet cell damage in rats. Int J Clin Pharmacol Ther. 2014;52:620-7 pubmed publisher

Beermann K, Ellis M, Sudan D, Harris M. Tacrolimus dose requirements in African-American and Caucasian kidney transplant recipients on mycophenolate and prednisone. Clin Transplant. 2014;28:762-7 pubmed publisher

Karipineni F, Campos S, Parsikia A, Durinka J, Chang P, Khanmoradi K, et al. Elimination of warm ischemia using the Ice Bag Technique does not decrease delayed graft function. Int J Surg. 2014;12:551-6 pubmed publisher

Timrott K, Vondran F, Kleine M, Warnecke G, Haverich A, Lehner F, et al. The impact of abdominal complications on the outcome after thoracic transplantation--a single center experience. Langenbecks Arch Surg. 2014;399:789-93 pubmed publisher

Davis N, Burke J, Kelly R, Shields W, Kheradmand F, Zimmermann A, et al. Predictors of 10-year pancreas allograft survival after simultaneous pancreas and kidney transplantation. Pancreas. 2014;43:750-4 pubmed publisher

Tsujita M, Inaguma D, Goto N, Yamamoto T, Hiramitsu T, Katayama A, et al. Beneficial effects of preemptive kidney transplantation on calcium and phosphorus disorders in early post-transplant recipients. Clin Exp Nephrol. 2015;19:319-24 pubmed publisher

Demmers M, Korevaar S, Betjes M, Weimar W, Rowshani A, Baan C. Limited efficacy of immunosuppressive drugs on CD8+ T cell-mediated and natural killer cell-mediated lysis of human renal tubular epithelial cells. Transplantation. 2014;97:1110-8 pubmed publisher

Funaro D, Lovett A, Leroux N, Powell J. A double-blind, randomized prospective study evaluating topical clobetasol propionate 0.05% versus topical tacrolimus 0.1% in patients with vulvar lichen sclerosus. J Am Acad Dermatol. 2014;71:84-91 pubmed publisher

Cho A, Tang Y, Davila J, Deng S, Chen L, Miller E, et al. Calcineurin signaling regulates neural induction through antagonizing the BMP pathway. Neuron. 2014;82:109-124 pubmed publisher

Fukushima A, Ohashi Y, Ebihara N, Uchio E, Okamoto S, Kumagai N, et al. Therapeutic effects of 0.1% tacrolimus eye drops for refractory allergic ocular diseases with proliferative lesion or corneal involvement. Br J Ophthalmol. 2014;98:1023-7 pubmed publisher

Stifft F, Stolk L, Undre N, van Hooff J, Christiaans M. Lower variability in 24-hour exposure during once-daily compared to twice-daily tacrolimus formulation in kidney transplantation. Transplantation. 2014;97:775-80 pubmed publisher

Rendina M, D Amato M, Castellaneta A, Castellaneta N, Brambilla N, Giacovelli G, et al. Antiviral activity and safety profile of silibinin in HCV patients with advanced fibrosis after liver transplantation: a randomized clinical trial. Transpl Int. 2014;27:696-704 pubmed publisher

Loers G, Cui Y, Neumaier I, Schachner M, Skerra A. A Fab fragment directed against the neural cell adhesion molecule L1 enhances functional recovery after injury of the adult mouse spinal cord. Biochem J. 2014;460:437-46 pubmed publisher

Sawamoto K, Huong T, Sugimoto N, Mizutani Y, Sai Y, Miyamoto K. Mechanisms of lower maintenance dose of tacrolimus in obese patients. Drug Metab Pharmacokinet. 2014;29:341-7 pubmed

Toledo F, Pérez L, Basiglio C, Ochoa J, Sanchez Pozzi E, Roma M. The Ca²⁺-calmodulin-Ca²⁺/calmodulin-dependent protein kinase II signaling pathway is involved in oxidative stress-induced mitochondrial permeability transition and apoptosis in isolated rat hepatocytes. Arch Toxicol. 2014;88:1695-709 pubmed publisher

Shimizu M, Ueno K, Ishikawa S, Tokuhisa Y, Inoue N, Yachie A. Successful multitarget therapy using mizoribine and tacrolimus for refractory Takayasu arteritis. Rheumatology (Oxford). 2014;53:1530-2 pubmed publisher

Kimura Y, Fujimura C, Ito Y, Takahashi T, Aiba S. Evaluation of the Multi-ImmunoTox Assay composed of 3 human cytokine reporter cells by examining immunological effects of drugs. Toxicol In Vitro. 2014;28:759-68 pubmed publisher

Diémé B, Halimi J, Emond P, Buchler M, Nadal Desbarat L, Blasco H, et al. Assessing the metabolic effects of calcineurin inhibitors in renal transplant recipients by urine metabolic profiling. Transplantation. 2014;98:195-201 pubmed publisher

Nasu R, Nannya Y, Shinohara A, Ichikawa M, Kurokawa M. Favorable outcomes of tacrolimus compared with cyclosporine A for GVHD prophylaxis in HSCT for standard-risk hematological diseases. Ann Hematol. 2014;93:1215-23 pubmed publisher

Eguchi R, Fujimori Y, Okada M, Tamaki H, Wakabayashi I, Ogawa H. Recombinant human soluble thrombomodulin attenuates FK506-induced endothelial dysfunction through prevention of Akt inactivation. Exp Cell Res. 2014;323:112-7 pubmed publisher

Wang Y, Zhou X, Debing Y, Chen K, van der Laan L, Neyts J, et al. Calcineurin inhibitors stimulate and mycophenolic acid inhibits replication of hepatitis E virus. Gastroenterology. 2014;146:1775-83 pubmed publisher

Mai H, Boeffard F, Longis J, Danger R, Martinet B, Haspot F, et al. IL-7 receptor blockade following T cell depletion promotes long-term allograft survival. J Clin Invest. 2014;124:1723-33 pubmed publisher

Yoshikawa K, Nakazawa Y, Katsuyama Y, Hirabayashi K, Saito S, Shigemura T, et al. Safety, tolerability, and feasibility of antifungal prophylaxis with micafungin at 2 mg/kg daily in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation. Infection. 2014;42:639-47 pubmed publisher

Sahin S, Ozakpinar O, Ak K, Eroglu M, Acikel M, Tetik S, et al. The protective effects of tacrolimus on rat uteri exposed to ischemia-reperfusion injury: a biochemical and histopathologic evaluation. Fertil Steril. 2014;101:1176-82 pubmed publisher

Lipson E, Bodell M, Kraus E, Sharfman W. Successful administration of ipilimumab to two kidney transplantation patients with metastatic melanoma. J Clin Oncol. 2014;32:e69-71 pubmed publisher

El Sheikh A, Koenderink J, Wouterse A, Van den Broek P, Verweij V, Masereeuw R, et al. Renal glucuronidation and multidrug resistance protein 2-/ multidrug resistance protein 4-mediated efflux of mycophenolic acid: interaction with cyclosporine and tacrolimus. Transl Res. 2014;164:46-56 pubmed publisher

Verma M, Awdishu L, Lane J, Park K, Bahur B, Lwin W, et al. Impact of single immunosuppressive drug withdrawal on lymphocyte immunoreactivity. J Surg Res. 2014;188:309-15 pubmed publisher

Yuda S, Mori T, Kato J, Koda Y, Kohashi S, Kikuchi T, et al. [Sodium-losing nephropathy caused by tacrolimus after allogeneic hematopoietic stem cell transplantation]. Rinsho Ketsueki. 2013;54:2187-91 pubmed

Abei M, Yagi M, Watanabe T, Sugimoto K, Tanno Y, Kaito K. [Nonspecific reacting materials that interferes tacrolimus assay by ACMIA]. Rinsho Byori. 2013;61:983-8 pubmed

Yargui L, Chettouh H, Boukni H, Mokhtari N, Berhoune A. Metabolic status of 1088 patients after renal transplantation: assessment of twelve years monitoring in Algiers Mustapha Hospital. Saudi J Kidney Dis Transpl. 2014;25:177-84 pubmed

Sivakumar V, Sriramnaveen P, Krishna C, Manjusha Y, Reddy Y, Sridhar N, et al. Role of fludrocortisone in the management of tacrolimus-induced hyperkalemia in a renal transplant recipient. Saudi J Kidney Dis Transpl. 2014;25:149-51 pubmed

Gounden V, Soldin S. Tacrolimus measurement: building a better immunoassay. Clin Chem. 2014;60:575-6 pubmed publisher

Provenzani A, Santeusanio A, Mathis E, Notarbartolo M, Labbozzetta M, Poma P, et al. Pharmacogenetic considerations for optimizing tacrolimus dosing in liver and kidney transplant patients. World J Gastroenterol. 2013;19:9156-73 pubmed publisher

Hitzler J, He W, Doyle J, Cairo M, Camitta B, Chan K, et al. Outcome of transplantation for acute lymphoblastic leukemia in children with Down syndrome. Pediatr Blood Cancer. 2014;61:1126-8 pubmed publisher

Wei T, Zheng Y, Dubowy M, Sharma M. Sandwich assay for tacrolimus using 2 antitacrolimus antibodies. Clin Chem. 2014;60:621-30 pubmed publisher

Vavić N, Rancic N, Dragojevic Simic V, Drasković Pavlović B, Bokonjic D, Ignjatovic L, et al. The influence of comedication on tacrolimus blood concentration in patients subjected to kidney transplantation: a retrospective study. Eur J Drug Metab Pharmacokinet. 2014;39:243-53 pubmed publisher

Talreja N, Butt A, Valle R, Fox R, Lockey R. Successful desensitization to agalsidase beta after anaphylaxis. Ann Allergy Asthma Immunol. 2014;112:71-2 pubmed publisher

Azzi J, Sayegh M, Mallat S. Calcineurin inhibitors: 40 years later, can't live without . J Immunol. 2013;191:5785-91 pubmed publisher

Hancock W. Effects of histone deacetylase inhibitors on alloresponses. Lancet Oncol. 2014;15:10-1 pubmed publisher

Choi S, Braun T, Chang L, Ferrara J, Pawarode A, Magenau J, et al. Vorinostat plus tacrolimus and mycophenolate to prevent graft-versus-host disease after related-donor reduced-intensity conditioning allogeneic haemopoietic stem-cell transplantation: a phase 1/2 trial. Lancet Oncol. 2014;15:87-95 pubmed publisher

Nanaeva B, Vardanian A. [Tacrolimus in perianal manifestations of Crohn's disease]. Eksp Klin Gastroenterol. 2013;:53-7 pubmed

Shilbayeh S, Zmeili R, Almardini R. The impact of CYP3A5 and MDR1 polymorphisms on tacrolimus dosage requirements and trough concentrations in pediatric renal transplant recipients. Saudi J Kidney Dis Transpl. 2013;24:1125-36 pubmed publisher

Fan J, Agyekum B, Venkatesan A, Hall D, Keightley A, Bjes E, et al. Noncanonical FK506-binding protein BDBT binds DBT to enhance its circadian function and forms foci at night. Neuron. 2013;80:984-96 pubmed publisher

Nakase H. [Tacrolimus therapy for patients with ulcerative colitis]. Nihon Shokakibyo Gakkai Zasshi. 2013;110:1916-21 pubmed

Gorgan M, Bockorny B, Lawlor M, Volpe J, Fiel Gan M. Pulmonary hemorrhage with capillaritis secondary to mycophenolate mofetil in a heart-transplant patient. Arch Pathol Lab Med. 2013;137:1684-7 pubmed publisher

Demmers M, Baan C, Janssen M, Litjens N, Ijzermans J, Betjes M, et al. Substantial proliferation of human renal tubular epithelial cell-reactive CD4+CD28null memory T cells, which is resistant to tacrolimus and everolimus. Transplantation. 2014;97:47-55 pubmed publisher

Manthripragada A, Pinheiro S, MaCurdy T, Saneinejad S, Worrall C, Kelman J, et al. Off-label topical calcineurin inhibitor use in children. Pediatrics. 2013;132:e1327-32 pubmed publisher

Werk A, Lefeldt S, Bruckmueller H, Hemmrich Stanisak G, Franke A, Roos M, et al. Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance. Clin Pharmacol Ther. 2014;95:416-22 pubmed publisher

Faralli J, Gagen D, Filla M, Crotti T, Peters D. Dexamethasone increases ?v?3 integrin expression and affinity through a calcineurin/NFAT pathway. Biochim Biophys Acta. 2013;1833:3306-3313 pubmed publisher

Tadano T, Takahashi H, Sugawara K, Sugimura M, Iwabuchi M, Mano Y, et al. [A case of calcineurin-inhibitor induced pain syndrome associated with tacrolimus therapy for ulcerative colitis]. Nihon Shokakibyo Gakkai Zasshi. 2013;110:1783-9 pubmed

Renner B, Klawitter J, Goldberg R, McCullough J, Ferreira V, Cooper J, et al. Cyclosporine induces endothelial cell release of complement-activating microparticles. J Am Soc Nephrol. 2013;24:1849-62 pubmed publisher

Bergmann T, Hennig S, Barraclough K, Isbel N, Staatz C. Population pharmacokinetics of tacrolimus in adult kidney transplant patients: impact of CYP3A5 genotype on starting dose. Ther Drug Monit. 2014;36:62-70 pubmed publisher

Rickels M, Kong S, Fuller C, Dalton Bakes C, Ferguson J, Reilly M, et al. Improvement in insulin sensitivity after human islet transplantation for type 1 diabetes. J Clin Endocrinol Metab. 2013;98:E1780-5 pubmed publisher

Sharp W, Fang Y, Han M, Zhang H, Hong Z, Banathy A, et al. Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission. FASEB J. 2014;28:316-26 pubmed publisher

Quigley M, Fletcher D, Zhang W, Nguyen V. Development of a reliable model of total abdominal wall transplantation. Plast Reconstr Surg. 2013;132:988-94 pubmed publisher

Nakamura T, Shinohara Y, Momozaki S, Yoshimoto T, Noguchi K. Co-stimulation with bone morphogenetic protein-9 and FK506 induces remarkable osteoblastic differentiation in rat dedifferentiated fat cells. Biochem Biophys Res Commun. 2013;440:289-94 pubmed publisher

Kapoor K, Bhatnagar J, Chufan E, Ambudkar S. Mutations in intracellular loops 1 and 3 lead to misfolding of human P-glycoprotein (ABCB1) that can be rescued by cyclosporine A, which reduces its association with chaperone Hsp70. J Biol Chem. 2013;288:32622-36 pubmed publisher

Imataki O, Uemura M, Shintani T, Matsumoto K. Reversible cerebral vasoconstriction syndrome resulted in cerebral infarction after allogeneic stem cell transplantation: a case report. Ann Hematol. 2014;93:895-6 pubmed publisher

Elens L, Hesselink D, Bouamar R, Budde K, de Fijter J, De Meyer M, et al. Impact of POR*28 on the pharmacokinetics of tacrolimus and cyclosporine A in renal transplant patients. Ther Drug Monit. 2014;36:71-9 pubmed publisher

Konig S, BROWNE S, Doleschal B, Schernthaner M, Poteser M, Mächler H, et al. Inhibition of Orai1-mediated Ca(2+) entry is a key mechanism of the antiproliferative action of sirolimus in human arterial smooth muscle. Am J Physiol Heart Circ Physiol. 2013;305:H1646-57 pubmed publisher

Welberry Smith M, Cherukuri A, Newstead C, Lewington A, Ahmad N, Menon K, et al. Alemtuzumab induction in renal transplantation permits safe steroid avoidance with tacrolimus monotherapy: a randomized controlled trial. Transplantation. 2013;96:1082-8 pubmed publisher

Martinez N, Chang H, Borrajo J, Gregory R. The co-chaperones Fkbp4/5 control Argonaute2 expression and facilitate RISC assembly. RNA. 2013;19:1583-93 pubmed publisher

Peddi V, Wiseman A, Chavin K, Slakey D. Review of combination therapy with mTOR inhibitors and tacrolimus minimization after transplantation. Transplant Rev (Orlando). 2013;27:97-107 pubmed publisher

Barbarino J, Staatz C, Venkataramanan R, Klein T, Altman R. PharmGKB summary: cyclosporine and tacrolimus pathways. Pharmacogenet Genomics. 2013;23:563-85 pubmed publisher

Rojas L, Herrero M, Boso V, García Eliz M, Poveda J, Librero J, et al. Meta-analysis and systematic review of the effect of the donor and recipient CYP3A5 6986A>G genotype on tacrolimus dose requirements in liver transplantation. Pharmacogenet Genomics. 2013;23:509-17 pubmed publisher

Penninga L, Penninga E, Møller C, Iversen M, Steinbruchel D, Gluud C. Tacrolimus versus cyclosporin as primary immunosuppression for lung transplant recipients. Cochrane Database Syst Rev. 2013;:CD008817 pubmed publisher

Vichyanond P, Kosrirukvongs P. Use of cyclosporine A and tacrolimus in treatment of vernal keratoconjunctivitis. Curr Allergy Asthma Rep. 2013;13:308-14 pubmed publisher

Ho E, Wong G, Craig J, Chapman J. Once-daily extended-release versus twice-daily standard-release tacrolimus in kidney transplant recipients: a systematic review. Transplantation. 2013;95:1120-8 pubmed publisher

Gijsen V, Hesselink D, Croes K, Koren G, de Wildt S. Prevalence of renal dysfunction in tacrolimus-treated pediatric transplant recipients: a systematic review. Pediatr Transplant. 2013;17:205-15 pubmed publisher

Nwaba A, MacQuillan G, Adams L, Garas G, Delriviere L, Augustson B, et al. Tacrolimus-induced thrombotic microangiopathy in orthotopic liver transplant patients: case series of four patients. Intern Med J. 2013;43:328-33 pubmed publisher

Hebert M, Zheng S, Hays K, Shen D, Davis C, Umans J, et al. Interpreting tacrolimus concentrations during pregnancy and postpartum. Transplantation. 2013;95:908-15 pubmed publisher

Sekiguchi Y, Shimada A, Imai H, Wakabayashi M, Sugimoto K, Nakamura N, et al. Epstein-Barr virus-negative, CD5-positive diffuse large B-cell lymphoma developing after treatment with oral tacrolimus for mixed connective tissue disease : a case report and review of the literature. J Clin Exp Hematop. 2012;52:211-8 pubmed

Rath T. Tacrolimus in transplant rejection. Expert Opin Pharmacother. 2013;14:115-22 pubmed publisher

Wang S, Cao J, Liu X, Hu H, Shi J, Zhang S, et al. Putative calcium channels CchA and MidA play the important roles in conidiation, hyphal polarity and cell wall components in Aspergillus nidulans. PLoS ONE. 2012;7:e46564 pubmed publisher

Matsubara S, Kondo K, Sugaya K, Miyamoto K. Effects of tacrolimus on dermatomyositis and polymyositis: a prospective, open, non-randomized study of nine patients and a review of the literature. Clin Rheumatol. 2012;31:1493-8 pubmed publisher

Rabie R, Mumtaz K, Renner E. Efficacy of antiviral therapy for hepatitis C after liver transplantation with cyclosporine and tacrolimus: a systematic review and meta-analysis. Liver Transpl. 2013;19:36-48 pubmed publisher

Gijsen V, Madadi P, Dube M, Hesselink D, Koren G, de Wildt S. Tacrolimus-induced nephrotoxicity and genetic variability: a review. Ann Transplant. 2012;17:111-21 pubmed

Rodríguez Perálvarez M, Germani G, Darius T, Lerut J, Tsochatzis E, Burroughs A. Tacrolimus trough levels, rejection and renal impairment in liver transplantation: a systematic review and meta-analysis. Am J Transplant. 2012;12:2797-814 pubmed

Kawahata K. [Treatment of rheumatic diseases: current status and future prospective. Topics: II. Immunosuppressant/antirheumatic drugs; 8. Tacrolimus]. Nihon Naika Gakkai Zasshi. 2011;100:2948-53 pubmed

McSharry K, Dalzell A, Leiper K, El Matary W. Systematic review: the role of tacrolimus in the management of Crohn's disease. Aliment Pharmacol Ther. 2011;34:1282-94 pubmed publisher

Tsuji H, Miyoshi S, Ikegami Y, Hida N, Asada H, Togashi I, et al. Xenografted human amniotic membrane-derived mesenchymal stem cells are immunologically tolerated and transdifferentiated into cardiomyocytes. Circ Res. 2010;106:1613-23 pubmed publisher

Liu R, Murphy T. Reversible cyclosporin A-sensitive mitochondrial depolarization occurs within minutes of stroke onset in mouse somatosensory cortex in vivo: a two-photon imaging study. J Biol Chem. 2009;284:36109-17 pubmed publisher

Kayama H, Koga R, Atarashi K, Okuyama M, Kimura T, Mak T, et al. NFATc1 mediates Toll-like receptor-independent innate immune responses during Trypanosoma cruzi infection. PLoS Pathog. 2009;5:e1000514 pubmed publisher

Bieri M, Oroszlan M, Zuppinger C, Mohacsi P. Biosynthesis and expression of VE-cadherin is regulated by the PI3K/mTOR signaling pathway. Mol Immunol. 2009;46:866-72 pubmed publisher

Carlson M, Conboy I. Loss of stem cell regenerative capacity within aged niches. Aging Cell. 2007;6:371-82 pubmed