product summary
company name :
MilliporeSigma
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-Actin, α-Smooth Muscle - FITC antibody produced in mouse
catalog :
F3777
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
1A4
reactivity :
human, mouse, rat, dogs, chicken, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 398
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:400; loading ...; fig 2e
Kasahara K, Sasaki N, Amin H, Tanaka T, Horibe S, Yamashita T, et al. Depletion of Foxp3+ regulatory T cells augments CD4+ T cell immune responses in atherosclerosis-prone hypercholesterolemic mice. Heliyon. 2022;8:e09981 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...
Richards M, Nwadozi E, Pal S, Martinsson P, Kaakinen M, Gloger M, et al. Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner. elife. 2022;11: pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 3k
Verginadis I, Avgousti H, Monslow J, Skoufos G, Chinga F, Kim K, et al. A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression. Nat Cell Biol. 2022;24:940-953 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1e
Humeres C, Shinde A, Hanna A, Alex L, Hern xe1 ndez S, Li R, et al. Smad7 effects on TGF-β and ErbB2 restrain myofibroblast activation and protect from postinfarction heart failure. J Clin Invest. 2022;132: pubmed publisher
  • immunohistochemistry; mouse; 1:800; loading ...; fig 1c
Kiepura A, Stachyra K, Wisniewska A, Kus K, Czepiel K, Suski M, et al. The Anti-Atherosclerotic Action of FFAR4 Agonist TUG-891 in ApoE-Knockout Mice Is Associated with Increased Macrophage Polarization towards M2 Phenotype. Int J Mol Sci. 2021;22: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:400; loading ...; fig 2c
Götz P, Braumandl A, Kübler M, Kumaraswami K, Ishikawa Ankerhold H, Lasch M, et al. C3 Deficiency Leads to Increased Angiogenesis and Elevated Pro-Angiogenic Leukocyte Recruitment in Ischemic Muscle Tissue. Int J Mol Sci. 2021;22: pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:500; loading ...; fig e8c
  • immunohistochemistry - paraffin section; mouse; 1:500; fig e7g
Newman A, Serbulea V, Baylis R, Shankman L, Bradley X, Alencar G, et al. Multiple cell types contribute to the atherosclerotic lesion fibrous cap by PDGFRβ and bioenergetic mechanisms. Nat Metab. 2021;3:166-181 pubmed publisher
  • flow cytometry; mouse; 1:500; loading ...; fig s1c, s10a
Zhang J, Li Y, Liu Q, Huang Y, Li R, Wu T, et al. Sirt6 Alleviated Liver Fibrosis by Deacetylating Conserved Lysine 54 on Smad2 in Hepatic Stellate Cells. Hepatology. 2021;73:1140-1157 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; fig 5a
Lau A, Li Z, Danai L, Westermark A, Darnell A, Ferreira R, et al. Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma. elife. 2020;9: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 5a
Miyawaki T, Morikawa S, Susaki E, Nakashima A, Takeuchi H, Yamaguchi S, et al. Visualization and molecular characterization of whole-brain vascular networks with capillary resolution. Nat Commun. 2020;11:1104 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 2f
van de Vlekkert D, Demmers J, Nguyen X, Campos Y, Machado E, Annunziata I, et al. Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis. Sci Adv. 2019;5:eaav3270 pubmed publisher
  • immunohistochemistry; mouse; 1:300; loading ...; fig 1j
Das S, Goldstone A, Wang H, Farry J, D Amato G, Paulsen M, et al. A Unique Collateral Artery Development Program Promotes Neonatal Heart Regeneration. Cell. 2019;176:1128-1142.e18 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 1b
Qin L, Min W, Xin S. AIP1 suppresses transplant arteriosclerosis through inhibition of vascular smooth muscle cell inflammatory response to IFNγ. Anat Rec (Hoboken). 2018;: pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 7c
Kim J, Park D, Bae H, Park D, Kim D, Lee C, et al. Impaired angiopoietin/Tie2 signaling compromises Schlemm's canal integrity and induces glaucoma. J Clin Invest. 2017;127:3877-3896 pubmed publisher
  • immunohistochemistry; mouse; 1:400; loading ...; fig 2f
Qiu C, Wang Y, Zhao H, Qin L, Shi Y, Zhu X, et al. The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis. Nat Commun. 2017;8:15426 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 10
Whitson J, Zhang X, Medvedovic M, Chen J, Wei Z, Monnier V, et al. Transcriptome of the GSH-Depleted Lens Reveals Changes in Detoxification and EMT Signaling Genes, Transport Systems, and Lipid Homeostasis. Invest Ophthalmol Vis Sci. 2017;58:2666-2684 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 1a
  • immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 1e
Gerarduzzi C, Kumar R, Trivedi P, Ajay A, Iyer A, Boswell S, et al. Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation. JCI Insight. 2017;2: pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 5a
Sawaguchi S, Varshney S, Ogawa M, Sakaidani Y, Yagi H, Takeshita K, et al. O-GlcNAc on NOTCH1 EGF repeats regulates ligand-induced Notch signaling and vascular development in mammals. elife. 2017;6: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 6
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig s1e
Nicolas N, Michel V, Bhushan S, Wahle E, Hayward S, Ludlow H, et al. Testicular activin and follistatin levels are elevated during the course of experimental autoimmune epididymo-orchitis in mice. Sci Rep. 2017;7:42391 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig s14a
Lee S, Rho S, Park H, Park J, Kim J, Lee I, et al. Carbohydrate-binding protein CLEC14A regulates VEGFR-2- and VEGFR-3-dependent signals during angiogenesis and lymphangiogenesis. J Clin Invest. 2017;127:457-471 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 2f
Yang Z, Peng Y, Gopalan A, Gao D, Chen Y, Joyner A. Stromal hedgehog signaling maintains smooth muscle and hampers micro-invasive prostate cancer. Dis Model Mech. 2017;10:39-52 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig s6f
Pu W, Zhang H, Huang X, Tian X, He L, Wang Y, et al. Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration. Nat Commun. 2016;7:13369 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 3c
Gautam J, Zhang X, Yao Y. The role of pericytic laminin in blood brain barrier integrity maintenance. Sci Rep. 2016;6:36450 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500
  • immunohistochemistry; mouse; 1:500; fig 3
Ramo K, Sugamura K, Craige S, Keaney J, Davis R. Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development. elife. 2016;5: pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; fig s14
Evrard S, Lecce L, Michelis K, Nomura Kitabayashi A, Pandey G, Purushothaman K, et al. Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability. Nat Commun. 2016;7:11853 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 4
Greulich F, Rudat C, Farin H, Christoffels V, Kispert A. Lack of Genetic Interaction between Tbx18 and Tbx2/Tbx20 in Mouse Epicardial Development. PLoS ONE. 2016;11:e0156787 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 5c
Yu W, Huang X, Tian X, Zhang H, He L, Wang Y, et al. GATA4 regulates Fgf16 to promote heart repair after injury. Development. 2016;143:936-49 pubmed publisher
  • immunohistochemistry; human; 1:500; fig 1
Patel K, AVEN L, Shao F, Krishnamoorthy N, Duvall M, Levy B, et al. Mast cell-derived neurotrophin 4 mediates allergen-induced airway hyperinnervation in early life. Mucosal Immunol. 2016;9:1466-1476 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; fig 4a
Avgustinova A, Iravani M, Robertson D, Fearns A, Gao Q, Klingbeil P, et al. Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness. Nat Commun. 2016;7:10305 pubmed publisher
  • immunocytochemistry; mouse; fig 5
Kitayama M, Mizutani K, Maruoka M, Mandai K, Sakakibara S, Ueda Y, et al. A Novel Nectin-mediated Cell Adhesion Apparatus That Is Implicated in Prolactin Receptor Signaling for Mammary Gland Development. J Biol Chem. 2016;291:5817-31 pubmed publisher
  • immunohistochemistry; human; 1:200; fig 1p
Patel A, Yamashita N, Ascano M, Bodmer D, Boehm E, Bodkin Clarke C, et al. RCAN1 links impaired neurotrophin trafficking to aberrant development of the sympathetic nervous system in Down syndrome. Nat Commun. 2015;6:10119 pubmed publisher
  • immunohistochemistry; mouse; 1:100-1:200; fig 5
Kraut B, Maier H, Kókai E, Fiedler K, Boettger T, Illing A, et al. Cardiac-Specific Activation of IKK2 Leads to Defects in Heart Development and Embryonic Lethality. PLoS ONE. 2015;10:e0141591 pubmed publisher
  • flow cytometry; human; fig 7b
Rohnalter V, Roth K, Finkernagel F, Adhikary T, Obert J, Dorzweiler K, et al. A multi-stage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and pro-inflammatory secretory phenotype. Oncotarget. 2015;6:40005-25 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 2
Zaitoun I, Johnson R, Jamali N, Almomani R, Wang S, Sheibani N, et al. Endothelium Expression of Bcl-2 Is Essential for Normal and Pathological Ocular Vascularization. PLoS ONE. 2015;10:e0139994 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:250; fig 1
Huan C, Yang T, Liang J, Xie T, Cheng L, Liu N, et al. Methylation-mediated BMPER expression in fibroblast activation in vitro and lung fibrosis in mice in vivo. Sci Rep. 2015;5:14910 pubmed publisher
  • immunohistochemistry; mouse
Grootaert M, da Costa Martins P, Bitsch N, Pintelon I, De Meyer G, Martinet W, et al. Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis. Autophagy. 2015;11:2014-2032 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; tbl 3
Keable A, Fenna K, Yuen H, Johnston D, Smyth N, Smith C, et al. Deposition of amyloid β in the walls of human leptomeningeal arteries in relation to perivascular drainage pathways in cerebral amyloid angiopathy. Biochim Biophys Acta. 2016;1862:1037-46 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 5
Rybinski K, Imtiyaz H, Mittica B, Drozdowski B, Fulmer J, Furuuchi K, et al. Targeting endosialin/CD248 through antibody-mediated internalization results in impaired pericyte maturation and dysfunctional tumor microvasculature. Oncotarget. 2015;6:25429-40 pubmed publisher
  • immunohistochemistry; mouse; 1:250; fig 3
He C, Medley S, Hu T, Hinsdale M, Lupu F, Virmani R, et al. PDGFRβ signalling regulates local inflammation and synergizes with hypercholesterolaemia to promote atherosclerosis. Nat Commun. 2015;6:7770 pubmed publisher
  • flow cytometry; rat; fig 4
Jacquin S, Rincheval V, Mignotte B, Richard S, Humbert M, Mercier O, et al. Inactivation of p53 Is Sufficient to Induce Development of Pulmonary Hypertension in Rats. PLoS ONE. 2015;10:e0131940 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 1
  • immunohistochemistry - paraffin section; human; fig 3
Shankman L, Gomez D, Cherepanova O, Salmon M, Alencar G, Haskins R, et al. KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis. Nat Med. 2015;21:628-37 pubmed publisher
  • flow cytometry; mouse; fig 1
Doni A, Musso T, Morone D, Bastone A, Zambelli V, Sironi M, et al. An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode. J Exp Med. 2015;212:905-25 pubmed publisher
  • immunohistochemistry; mouse; 1:400; fig  S2
Lei Z, van Mil A, Brandt M, Grundmann S, Hoefer I, Smits M, et al. MicroRNA-132/212 family enhances arteriogenesis after hindlimb ischaemia through modulation of the Ras-MAPK pathway. J Cell Mol Med. 2015;19:1994-2005 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig s2
Wilson C, Jurk D, Fullard N, Banks P, Page A, Luli S, et al. NFκB1 is a suppressor of neutrophil-driven hepatocellular carcinoma. Nat Commun. 2015;6:6818 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig 7
Li X, Ballantyne L, Che X, Mewburn J, Kang J, Barkley R, et al. Endogenously generated omega-3 fatty acids attenuate vascular inflammation and neointimal hyperplasia by interaction with free fatty acid receptor 4 in mice. J Am Heart Assoc. 2015;4: pubmed publisher
  • western blot; human; 1:1000; tbl 2
Chan N, He S, Spee C, Ishikawa K, Hinton D. Attenuation of choroidal neovascularization by histone deacetylase inhibitor. PLoS ONE. 2015;10:e0120587 pubmed publisher
  • immunohistochemistry; mouse; 1:500; fig 7
Johnson J, Folestad E, Rowley J, Noll E, Walker S, Lloyd C, et al. Pericytes contribute to airway remodeling in a mouse model of chronic allergic asthma. Am J Physiol Lung Cell Mol Physiol. 2015;308:L658-71 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; fig 4
Liu Q, Hu T, He L, Huang X, Tian X, Zhang H, et al. Genetic targeting of sprouting angiogenesis using Apln-CreER. Nat Commun. 2015;6:6020 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100
Kuznetsova N, Vodovozova E. Differential binding of plasma proteins by liposomes loaded with lipophilic prodrugs of methotrexate and melphalan in the bilayer. Biochemistry (Mosc). 2014;79:797-804 pubmed publisher
  • western blot; mouse; 1:1000; fig 2
Yao Y, Chen Z, Norris E, Strickland S. Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity. Nat Commun. 2014;5:3413 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:250
Mamuya F, Wang Y, Roop V, Scheiblin D, Zajac J, Duncan M. The roles of ?V integrins in lens EMT and posterior capsular opacification. J Cell Mol Med. 2014;18:656-70 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200
Song K, Chung J, Choi M, Jin H, Yin G, Kwon M, et al. Effectiveness of intracavernous delivery of adenovirus encoding Smad7 gene on erectile function in a mouse model of cavernous nerve injury. J Sex Med. 2014;11:51-63 pubmed publisher
  • immunohistochemistry - frozen section; human
Turnbull I, Karakikes I, Serrao G, Backeris P, Lee J, Xie C, et al. Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium. FASEB J. 2014;28:644-54 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:250
Ishikawa K, Yoshida S, Nakao S, Nakama T, Kita T, Asato R, et al. Periostin promotes the generation of fibrous membranes in proliferative vitreoretinopathy. FASEB J. 2014;28:131-42 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Maddaluno L, Rudini N, Cuttano R, Bravi L, Giampietro C, Corada M, et al. EndMT contributes to the onset and progression of cerebral cavernous malformations. Nature. 2013;498:492-6 pubmed publisher
  • immunocytochemistry; human; 1:250
Mendel T, Clabough E, Kao D, Demidova Rice T, Durham J, Zotter B, et al. Pericytes derived from adipose-derived stem cells protect against retinal vasculopathy. PLoS ONE. 2013;8:e65691 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200
Bohnenpoll T, Bettenhausen E, Weiss A, Foik A, Trowe M, Blank P, et al. Tbx18 expression demarcates multipotent precursor populations in the developing urogenital system but is exclusively required within the ureteric mesenchymal lineage to suppress a renal stromal fate. Dev Biol. 2013;380:25-36 pubmed publisher
  • immunohistochemistry - frozen section; mouse
Chatterjee S, Wang Y, Duncan M, Naik U. Junctional adhesion molecule-A regulates vascular endothelial growth factor receptor-2 signaling-dependent mouse corneal wound healing. PLoS ONE. 2013;8:e63674 pubmed publisher
  • immunohistochemistry; mouse; fig 5b
Cieslik K, Trial J, Carlson S, Taffet G, Entman M. Aberrant differentiation of fibroblast progenitors contributes to fibrosis in the aged murine heart: role of elevated circulating insulin levels. FASEB J. 2013;27:1761-71 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:100
Zimmerlin L, Donnenberg V, Rubin J, Donnenberg A. Mesenchymal markers on human adipose stem/progenitor cells. Cytometry A. 2013;83:134-40 pubmed publisher
  • immunocytochemistry; rat; 1:1000
Johnson K, Petersen Jones H, Thompson J, Hitomi K, Itoh M, Bakker E, et al. Vena cava and aortic smooth muscle cells express transglutaminases 1 and 4 in addition to transglutaminase 2. Am J Physiol Heart Circ Physiol. 2012;302:H1355-66 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100
Qi Y, Liang J, She Z, Cai Y, Wang J, Lei T, et al. MCP-induced protein 1 suppresses TNFalpha-induced VCAM-1 expression in human endothelial cells. FEBS Lett. 2010;584:3065-72 pubmed publisher
  • immunohistochemistry; mouse
Mailleux A, Overholtzer M, Schmelzle T, Bouillet P, Strasser A, Brugge J. BIM regulates apoptosis during mammary ductal morphogenesis, and its absence reveals alternative cell death mechanisms. Dev Cell. 2007;12:221-34 pubmed
Meng Z, Zhang S, Li W, Wang Y, Wang M, Liu X, et al. Cationic proteins from eosinophils bind bone morphogenetic protein receptors promoting vascular calcification and atherogenesis. Eur Heart J. 2023;44:2763-2783 pubmed publisher
Krolak T, Chan K, Kaplan L, Huang Q, Wu J, Zheng Q, et al. A High-Efficiency AAV for Endothelial Cell Transduction Throughout the Central Nervous System. Nat Cardiovasc Res. 2022;1:389-400 pubmed publisher
Kim D, Nam G, Seo E, Jun H. Inhibition of ChREBP ubiquitination via the ROS/Akt-dependent downregulation of Smurf2 contributes to lysophosphatidic acid-induced fibrosis in renal mesangial cells. J Biomed Sci. 2022;29:31 pubmed publisher
Kerdidani D, Aerakis E, Verrou K, Angelidis I, Douka K, Maniou M, et al. Lung tumor MHCII immunity depends on in situ antigen presentation by fibroblasts. J Exp Med. 2022;219: pubmed publisher
Cummins K, Bitterman P, Tschumperlin D, Wood D. A scalable 3D tissue culture pipeline to enable functional therapeutic screening for pulmonary fibrosis. APL Bioeng. 2021;5:046102 pubmed publisher
Sharp M, Cassidy J, Thornton T, Lyles J, Keable A, Gatherer M, et al. The α-dystrobrevins play a key role in maintaining the structure and function of the extracellular matrix-significance for protein elimination failure arteriopathies. Acta Neuropathol Commun. 2021;9:171 pubmed publisher
Novoyatleva T, Rai N, Kojonazarov B, Veeroju S, Ben Batalla I, Caruso P, et al. Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2. Commun Biol. 2021;4:1002 pubmed publisher
Rebling J, Ben Yehuda Greenwald M, Wietecha M, Werner S, Razansky D. Long-Term Imaging of Wound Angiogenesis with Large Scale Optoacoustic Microscopy. Adv Sci (Weinh). 2021;8:2004226 pubmed publisher
Manning J, Shah S, Nikolic A, Henshall T, Khew Goodall Y, Kumar S. The ubiquitin ligase NEDD4-2/NEDD4L regulates both sodium homeostasis and fibrotic signaling to prevent end-stage renal disease. Cell Death Dis. 2021;12:398 pubmed publisher
Liang Q, Zhang L, Xu H, Li J, Chen Y, Schwarz E, et al. Lymphatic muscle cells contribute to dysfunction of the synovial lymphatic system in inflammatory arthritis in mice. Arthritis Res Ther. 2021;23:58 pubmed publisher
Leimkühler N, Gleitz H, Ronghui L, Snoeren I, Fuchs S, Nagai J, et al. Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis. Cell Stem Cell. 2020;: pubmed publisher
Simion V, Zhou H, Haemmig S, Pierce J, Mendes S, Tesmenitsky Y, et al. A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus. Nat Commun. 2020;11:6135 pubmed publisher
Kim S, Ahn J, Yang H, Lee P, Koh G, Jeong Y. Cerebral amyloid angiopathy aggravates perivascular clearance impairment in an Alzheimer's disease mouse model. Acta Neuropathol Commun. 2020;8:181 pubmed publisher
MacGregor Sharp M, Saito S, Keable A, Gatherer M, Aldea R, Agarwal N, et al. Demonstrating a reduced capacity for removal of fluid from cerebral white matter and hypoxia in areas of white matter hyperintensity associated with age and dementia. Acta Neuropathol Commun. 2020;8:131 pubmed publisher
Becker L, O Connell J, Vo A, Cain M, Tampe D, Bizarro L, et al. Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer. Cell Rep. 2020;31:107701 pubmed publisher
Grubb S, Cai C, Hald B, Khennouf L, Murmu R, Jensen A, et al. Precapillary sphincters maintain perfusion in the cerebral cortex. Nat Commun. 2020;11:395 pubmed publisher
Tang J, Wang H, Huang X, Li F, Zhu H, Li Y, et al. Arterial Sca1+ Vascular Stem Cells Generate De Novo Smooth Muscle for Artery Repair and Regeneration. Cell Stem Cell. 2020;26:81-96.e4 pubmed publisher
Ishikawa K, Kohno R, Mori K, Murakami Y, Nakao S, Akiyama M, et al. Increased expression of periostin and tenascin-C in eyes with neovascular glaucoma secondary to PDR. Graefes Arch Clin Exp Ophthalmol. 2020;258:621-628 pubmed publisher
Liu W, Meridew J, Aravamudhan A, Ligresti G, Tschumperlin D, Tan Q. Targeted regulation of fibroblast state by CRISPR-mediated CEBPA expression. Respir Res. 2019;20:281 pubmed publisher
Zein Hammoud M, Standley P. Optimized Modeled Myofascial Release Enhances Wound Healing in 3-Dimensional Bioengineered Tendons: Key Roles for Fibroblast Proliferation and Collagen Remodeling. J Manipulative Physiol Ther. 2019;42:551-564 pubmed publisher
Bauknight D, Osinski V, Dasa S, Nguyen A, Marshall M, Hartman J, et al. Importance of thorough tissue and cellular level characterization of targeted drugs in the evaluation of pharmacodynamic effects. PLoS ONE. 2019;14:e0224917 pubmed publisher
Kefaloyianni E, Keerthi Raja M, Schumacher J, Muthu M, Krishnadoss V, Waikar S, et al. Proximal Tubule-Derived Amphiregulin Amplifies and Integrates Profibrotic EGF Receptor Signals in Kidney Fibrosis. J Am Soc Nephrol. 2019;30:2370-2383 pubmed publisher
Rabieifar P, Zhuang T, Costa T, Zhao M, Stromblad S. Normal mammary gland development after MMTV-Cre mediated conditional PAK4 gene depletion. Sci Rep. 2019;9:14436 pubmed publisher
Mintz E, Passipieri J, Franklin I, Toscano V, Afferton E, Sharma P, et al. Long-Term Evaluation of Functional Outcomes Following Rat Volumetric Muscle Loss Injury and Repair. Tissue Eng Part A. 2020;26:140-156 pubmed publisher
Liang Q, Zhang L, Wood R, Ji R, Boyce B, Schwarz E, et al. Avian Reticuloendotheliosis Viral Oncogene Related B Regulates Lymphatic Endothelial Cells during Vessel Maturation and Is Required for Lymphatic Vessel Function in Adult Mice. Am J Pathol. 2019;189:2516-2530 pubmed publisher
Huycke T, Miller B, Gill H, Nerurkar N, Sprinzak D, Mahadevan L, et al. Genetic and Mechanical Regulation of Intestinal Smooth Muscle Development. Cell. 2019;179:90-105.e21 pubmed publisher
Cerqueira D, Hemker S, Bodnar A, Ortiz D, Oladipupo F, Mukherjee E, et al. In utero exposure to maternal diabetes impairs nephron progenitor differentiation. Am J Physiol Renal Physiol. 2019;317:F1318-F1330 pubmed publisher
Elwakeel E, Brüggemann M, Fink A, Schulz M, Schmid T, Savai R, et al. Phenotypic Plasticity of Fibroblasts during Mammary Carcinoma Development. Int J Mol Sci. 2019;20: pubmed publisher
Wang X, Sommerfeld M, Jahn Hofmann K, Cai B, Filliol A, Remotti H, et al. A Therapeutic Silencing RNA Targeting Hepatocyte TAZ Prevents and Reverses Fibrosis in Nonalcoholic Steatohepatitis in Mice. Hepatol Commun. 2019;3:1221-1234 pubmed publisher
Durgin B, Hahn S, Schmidt H, Miller M, Hafeez N, Mathar I, et al. Loss of smooth muscle CYB5R3 amplifies angiotensin II-induced hypertension by increasing sGC heme oxidation. JCI Insight. 2019;4: pubmed publisher
Liu C, Zhang X, Liu J, Wang Y, Sukhova G, Wojtkiewicz G, et al. Na+-H+ exchanger 1 determines atherosclerotic lesion acidification and promotes atherogenesis. Nat Commun. 2019;10:3978 pubmed publisher
Marx C, Novotny J, Salbeck D, Zellner K, Nicolai L, Pekayvaz K, et al. Eosinophil-platelet interactions promote atherosclerosis and stabilize thrombosis with eosinophil extracellular traps. Blood. 2019;134:1859-1872 pubmed publisher
Willecke F, Rupprecht B, Gissler M, Pfeiffer K, Anto Michel N, Stachon P, et al. Tumor Necrosis Factor Receptor-Associated Factor 5 Promotes Arterial Neointima Formation through Smooth Muscle Cell Proliferation. J Vasc Res. 2019;56:308-319 pubmed publisher
Bresler A, Vogel J, Niederer D, Gray D, Schmitz Rixen T, Troidl K. Development of an Exercise Training Protocol to Investigate Arteriogenesis in a Murine Model of Peripheral Artery Disease. Int J Mol Sci. 2019;20: pubmed publisher
Jamali N, Song Y, Sorenson C, Sheibani N. 1,25(OH)2D3 regulates the proangiogenic activity of pericyte through VDR-mediated modulation of VEGF production and signaling of VEGF and PDGF receptors. FASEB Bioadv. 2019;1:415-434 pubmed publisher
Méndez Barbero N, Gutiérrez Muñoz C, Madrigal Matute J, Minguez P, Egido J, Michel J, et al. A major role of TWEAK/Fn14 axis as a therapeutic target for post-angioplasty restenosis. EBioMedicine. 2019;46:274-289 pubmed publisher
Morán Salvador E, García Macia M, Sivaharan A, Sabater L, Zaki M, Oakley F, et al. Fibrogenic Activity of MECP2 Is Regulated by Phosphorylation in Hepatic Stellate Cells. Gastroenterology. 2019;157:1398-1412.e9 pubmed publisher
Kasza I, Adler D, Nelson D, Eric Yen C, Dumas S, Ntambi J, et al. Evaporative cooling provides a major metabolic energy sink. Mol Metab. 2019;27:47-61 pubmed publisher
Zaitoun I, Wintheiser C, Jamali N, Wang S, Suscha A, Darjatmoko S, et al. Bcl-2 Expression in Pericytes and Astrocytes Impacts Vascular Development and Homeostasis. Sci Rep. 2019;9:9700 pubmed publisher
Li Y, Lv Z, He L, Huang X, Zhang S, Zhao H, et al. Genetic Tracing Identifies Early Segregation of the Cardiomyocyte and Nonmyocyte Lineages. Circ Res. 2019;125:343-355 pubmed publisher
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product information
Product No. :
F3777
Product Name :
Monoclonal Anti-Actin, α-Smooth Muscle - FITC antibody produced in mouse
Host :
mouse
Conjugate :
FITC conjugate
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
1A4
Applications/Description :
Suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500 using human tonsil or appendix
Species Reactivity :
rabbit, guinea pig, mouse, chicken, snake, sheep, goat, human, frog, rat, canine, bovine
Isotype :
IgG2a
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA