Published Application/Species/Sample/Dilution | Reference |
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- immunohistochemistry - frozen section; mouse; loading ...; fig 1a
| Alles S, Nascimento F, Lujan R, Luiz A, Millet Q, Bangash M, et al. Sensory neuron-derived NaV1.7 contributes to dorsal horn neuron excitability. Sci Adv. 2020;6:eaax4568 pubmed publisher
|
- ChIP-Seq; human; loading ...; fig 2c
| Lamaa A, Humbert J, Aguirrebengoa M, Cheng X, Nicolas E, Cote J, et al. Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation. elife. 2020;9: pubmed publisher
|
- western blot; mouse; 1:1000; loading ...; fig 2c
| Hota S, Johnson J, Verschueren E, Thomas R, Blotnick A, Zhu Y, et al. Dynamic BAF chromatin remodeling complex subunit inclusion promotes temporally distinct gene expression programs in cardiogenesis. Development. 2019;: pubmed publisher
|
- immunohistochemistry - paraffin section; human
- immunohistochemistry; human
| Lin J, Izar B, Wang S, Yapp C, Mei S, Shah P, et al. Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes. elife. 2018;7: pubmed publisher
|
- immunocytochemistry; human; 1:500; loading ...; fig 1b
| Kanellopoulos A, Koenig J, Huang H, Pyrski M, Millet Q, Lolignier S, et al. Mapping protein interactions of sodium channel NaV1.7 using epitope-tagged gene-targeted mice. EMBO J. 2018;37:427-445 pubmed publisher
|
- immunoprecipitation; human; loading ...; fig 1b
- western blot; human; loading ...; fig 1c
| Sasaki Y, Hidaka T, Ueno T, Akiba Takagi M, Oliva Trejo J, Seki T, et al. Sorting Nexin 9 facilitates podocin endocytosis in the injured podocyte. Sci Rep. 2017;7:43921 pubmed publisher
|
- immunocytochemistry; rat; 1:50; loading ...; fig 1c
| Goodman L, Baddeley D, Ambroziak W, Waites C, Garner C, Soeller C, et al. N-terminal SAP97 isoforms differentially regulate synaptic structure and postsynaptic surface pools of AMPA receptors. Hippocampus. 2017;27:668-682 pubmed publisher
|
- western blot; human; loading ...; fig 1h
| Deng X, Shao G, Zhang H, Li C, Zhang D, Cheng L, et al. Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor to promote prostate cancer cell growth. Oncogene. 2017;36:1223-1231 pubmed publisher
|
- western blot; human; 1:500; loading ...; fig 1f
| Hansen R, Mund A, Poulsen S, Sandoval M, Klement K, Tsouroula K, et al. SCAI promotes DNA double-strand break repair in distinct chromosomal contexts. Nat Cell Biol. 2016;18:1357-1366 pubmed publisher
|
- immunocytochemistry; human
| Scholefield J, Henriques R, Savulescu A, Fontan E, Boucharlat A, Laplantine E, et al. Super-resolution microscopy reveals a preformed NEMO lattice structure that is collapsed in incontinentia pigmenti. Nat Commun. 2016;7:12629 pubmed publisher
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| Pakchuen S, Ishibashi M, Takakusagi E, Shirahige K, Sutani T. Physical Association of Saccharomyces cerevisiae Polo-like Kinase Cdc5 with Chromosomal Cohesin Facilitates DNA Damage Response. J Biol Chem. 2016;291:17228-46 pubmed publisher
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- western blot; rat; fig 3a
| Bott L, Salomons F, Maric D, Liu Y, Merry D, Fischbeck K, et al. The polyglutamine-expanded androgen receptor responsible for spinal and bulbar muscular atrophy inhibits the APC/C(Cdh1) ubiquitin ligase complex. Sci Rep. 2016;6:27703 pubmed publisher
|
- immunoprecipitation; human; fig 4
| Glenewinkel F, Cohen M, King C, Kaspar S, Bamberg Lemper S, Mymryk J, et al. The adaptor protein DCAF7 mediates the interaction of the adenovirus E1A oncoprotein with the protein kinases DYRK1A and HIPK2. Sci Rep. 2016;6:28241 pubmed publisher
|
- immunohistochemistry - frozen section; mouse; fig 2
- western blot; mouse; fig 1
| Wang H, Wang R, Carrera I, Xu S, Lakshmana M. TFEB Overexpression in the P301S Model of Tauopathy Mitigates Increased PHF1 Levels and Lipofuscin Puncta and Rescues Memory Deficits. Eneuro. 2016;3: pubmed publisher
|
- chromatin immunoprecipitation; human; fig 2
- EMSA; human; fig 2
- immunocytochemistry; human; fig s1
| Ferrán B, Martà Pà mies I, Alonso J, RodrÃguez Calvo R, Aguiló S, Vidal F, et al. The nuclear receptor NOR-1 regulates the small muscle protein, X-linked (SMPX) and myotube differentiation. Sci Rep. 2016;6:25944 pubmed publisher
|
- immunoprecipitation; Drosophila melanogaster; 500 ul/ml; fig 4
| Le T, Vuong L, Kim A, Hsu Y, Choi K. 14-3-3 proteins regulate Tctp-Rheb interaction for organ growth in Drosophila. Nat Commun. 2016;7:11501 pubmed publisher
|
- western blot; human; 1:1000; fig 2
| Aizawa S, Okamoto T, Sugiyama Y, Kouwaki T, Ito A, Suzuki T, et al. TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis. Nat Commun. 2016;7:11379 pubmed publisher
|
- western blot; human; 1:1000; fig 7
| Watanabe Y, Papoutsoglou P, Maturi V, Tsubakihara Y, Hottiger M, Heldin C, et al. Regulation of Bone Morphogenetic Protein Signaling by ADP-ribosylation. J Biol Chem. 2016;291:12706-23 pubmed publisher
|
- western blot; human; fig 4
| Beard J, Tenga A, Hills J, Hoyer J, Cherian M, Wang Y, et al. The orphan nuclear receptor NR4A2 is part of a p53-microRNA-34 network. Sci Rep. 2016;6:25108 pubmed publisher
|
- chromatin immunoprecipitation; human; fig s4
- immunocytochemistry; human; fig s4
- western blot; human; fig 1
| Huang C, Cheng J, Bawa Khalfe T, Yao X, Chin Y, Yeh E. SUMOylated ORC2 Recruits a Histone Demethylase to Regulate Centromeric Histone Modification and Genomic Stability. Cell Rep. 2016;15:147-157 pubmed publisher
|
- immunoprecipitation; mouse; fig 4b
| Kuzuya A, Zoltowska K, Post K, Arimon M, Li X, Svirsky S, et al. Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta. BMC Biol. 2016;14:25 pubmed publisher
|
- western blot; human; 1:3000; fig 4c
| Kadir R, Harel T, Markus B, Perez Y, Bakhrat A, Cohen I, et al. ALFY-Controlled DVL3 Autophagy Regulates Wnt Signaling, Determining Human Brain Size. PLoS Genet. 2016;12:e1005919 pubmed publisher
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- western blot; mouse; 1:10,000; fig 3f
| Gruosso T, Mieulet V, Cardon M, Bourachot B, Kieffer Y, Devun F, et al. Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients. EMBO Mol Med. 2016;8:527-49 pubmed publisher
|
- western blot; human; 1:5000; fig 2
| Douanne T, Gavard J, Bidère N. The paracaspase MALT1 cleaves the LUBAC subunit HOIL1 during antigen receptor signaling. J Cell Sci. 2016;129:1775-80 pubmed publisher
|
- western blot; human; 1:1000; fig s11
| Nagao M, Ogata T, Sawada Y, Gotoh Y. Zbtb20 promotes astrocytogenesis during neocortical development. Nat Commun. 2016;7:11102 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Lee J, Kim H, Rho S, Lee S. eIF3f reduces tumor growth by directly interrupting clusterin with anti-apoptotic property in cancer cells. Oncotarget. 2016;7:18541-57 pubmed publisher
|
- immunocytochemistry; mouse; 1:10,000; fig s6
| Park S, Yun Y, Lim J, Kim M, Kim S, Kim J, et al. Stabilin-2 modulates the efficiency of myoblast fusion during myogenic differentiation and muscle regeneration. Nat Commun. 2016;7:10871 pubmed publisher
|
- western blot; mouse; 1:1000; fig 3
- western blot; human; 1:1000; fig 3
| Grampa V, Delous M, Zaidan M, Odye G, Thomas S, Elkhartoufi N, et al. Novel NEK8 Mutations Cause Severe Syndromic Renal Cystic Dysplasia through YAP Dysregulation. PLoS Genet. 2016;12:e1005894 pubmed publisher
|
- immunoprecipitation; human; 1:5000; fig 4
| Zhang X, Peng D, Xi Y, Yuan C, Sagum C, Klein B, et al. G9a-mediated methylation of ERα links the PHF20/MOF histone acetyltransferase complex to hormonal gene expression. Nat Commun. 2016;7:10810 pubmed publisher
|
- western blot; human; 1:3000; fig 3f
| Choi W, de Poot S, Lee J, Kim J, Han D, Kim Y, et al. Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation. Nat Commun. 2016;7:10963 pubmed publisher
|
- immunocytochemistry; human; 1:500; fig 4e
- western blot; human; 1:5000; fig 4g
| Xu Q, Zhang Y, Wei Q, Huang Y, Hu J, Ling K. Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis. Nat Commun. 2016;7:10777 pubmed publisher
|
- immunoprecipitation; human; fig s2e
- immunocytochemistry; human; fig s2c
- western blot; human; fig s2a
| Oswald F, Rodriguez P, Giaimo B, Antonello Z, Mira L, Mittler G, et al. A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes. Nucleic Acids Res. 2016;44:4703-20 pubmed publisher
|
- western blot; human; fig 5f
| Randles L, Anchoori R, Roden R, Walters K. The Proteasome Ubiquitin Receptor hRpn13 and Its Interacting Deubiquitinating Enzyme Uch37 Are Required for Proper Cell Cycle Progression. J Biol Chem. 2016;291:8773-83 pubmed publisher
|
- immunoprecipitation; human; fig 4
- western blot; human; fig 4
| Lee S, Jeong A, Park J, Han S, Jang C, Kim K, et al. IK-guided PP2A suppresses Aurora B activity in the interphase of tumor cells. Cell Mol Life Sci. 2016;73:3375-86 pubmed publisher
|
- immunoprecipitation; human; fig 1b
- western blot; human; fig 1b
| Hong J, Lee J, Chung I. Telomerase activates transcription of cyclin D1 gene through an interaction with NOL1. J Cell Sci. 2016;129:1566-79 pubmed publisher
|
- western blot; human; 1:5000; fig 1
| Vukićević T, Schulz M, Faust D, Klussmann E. The Trafficking of the Water Channel Aquaporin-2 in Renal Principal Cells-a Potential Target for Pharmacological Intervention in Cardiovascular Diseases. Front Pharmacol. 2016;7:23 pubmed publisher
|
- western blot; human; fig 5
| Castaño J, Morera C, Sesé B, Boue S, Bonet Costa C, Marti M, et al. SETD7 Regulates the Differentiation of Human Embryonic Stem Cells. PLoS ONE. 2016;11:e0149502 pubmed publisher
|
- western blot; human; fig 1
| Baietti M, Simíček M, Abbasi Asbagh L, Radaelli E, Lievens S, Crowther J, et al. OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination. EMBO Mol Med. 2016;8:288-303 pubmed publisher
|
- western blot; human; fig 1
| Kim J, He X, Orr B, Wutz G, Hill V, Peters J, et al. Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2. PLoS Genet. 2016;12:e1005865 pubmed publisher
|
- immunoprecipitation; mouse; fig 4
- western blot; mouse; 1:5000; fig 4
| Tai D, Liu Y, Hsu W, Ma Y, Cheng S, Liu S, et al. MeCP2 SUMOylation rescues Mecp2-mutant-induced behavioural deficits in a mouse model of Rett syndrome. Nat Commun. 2016;7:10552 pubmed publisher
|
- western blot; human; 1:5000; fig 5
| Melero R, Hug N, López Perrote A, Yamashita A, Cáceres J, Llorca O. The RNA helicase DHX34 functions as a scaffold for SMG1-mediated UPF1 phosphorylation. Nat Commun. 2016;7:10585 pubmed publisher
|
- immunoprecipitation; mouse
- western blot; mouse
| de Dieuleveult M, Yen K, Hmitou I, Depaux A, Boussouar F, Bou Dargham D, et al. Genome-wide nucleosome specificity and function of chromatin remodellers in ES cells. Nature. 2016;530:113-6 pubmed publisher
|
- western blot; human; 1:1000; fig 3a
| Martone J, Briganti F, Legnini I, Morlando M, Picillo E, Sthandier O, et al. The lack of the Celf2a splicing factor converts a Duchenne genotype into a Becker phenotype. Nat Commun. 2016;7:10488 pubmed publisher
|
- western blot; human; fig s1
| Lechtenberg B, Rajput A, Sanishvili R, Dobaczewska M, Ware C, Mace P, et al. Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation. Nature. 2016;529:546-50 pubmed publisher
|
- western blot; mouse; fig s4b
| Kibe T, Zimmermann M, de Lange T. TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres. Mol Cell. 2016;61:236-46 pubmed publisher
|
- western blot; human; fig 1
- western blot; mouse; fig 1
| M L, P P, T K, M P, E S, J P, et al. Essential role of HDAC6 in the regulation of PD-L1 in melanoma. Mol Oncol. 2016;10:735-750 pubmed publisher
|
- western blot; human; 1:4000; fig 4
| Pan H, Guan D, Liu X, Li J, Wang L, Wu J, et al. SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2. Cell Res. 2016;26:190-205 pubmed publisher
|
- immunoprecipitation; human; fig 3
- western blot; human; fig 3
| Zhang Q, Wan M, Shi J, Horita D, Miller L, Kute T, et al. Yin Yang 1 promotes mTORC2-mediated AKT phosphorylation. J Mol Cell Biol. 2016;8:232-43 pubmed publisher
|
- immunoprecipitation; human; 1:20,000; fig 1
- western blot; human; 1:20,000; fig 1
| Zhang C, Liu J, Zhao Y, Yue X, Zhu Y, Wang X, et al. Glutaminase 2 is a novel negative regulator of small GTPase Rac1 and mediates p53 function in suppressing metastasis. elife. 2016;5:e10727 pubmed publisher
|
- western blot; human; fig 3b
| Li N, Dhar S, Chen T, Kan P, Wei Y, Kim J, et al. JARID1D Is a Suppressor and Prognostic Marker of Prostate Cancer Invasion and Metastasis. Cancer Res. 2016;76:831-43 pubmed publisher
|
- western blot; human; fig 3
| Kiel C, Benisty H, Lloréns Rico V, Serrano L. The yin-yang of kinase activation and unfolding explains the peculiarity of Val600 in the activation segment of BRAF. elife. 2016;5:e12814 pubmed publisher
|
- immunocytochemistry; Leishmania amazonensis; 1:500; fig 1
| Mittra B, Laranjeira Silva M, Perrone Bezerra de Menezes J, Jensen J, Michailowsky V, Andrews N. A Trypanosomatid Iron Transporter that Regulates Mitochondrial Function Is Required for Leishmania amazonensis Virulence. PLoS Pathog. 2016;12:e1005340 pubmed publisher
|
- immunoprecipitation; human; fig s3b
| Arimoto Matsuzaki K, Saito H, Takekawa M. TIA1 oxidation inhibits stress granule assembly and sensitizes cells to stress-induced apoptosis. Nat Commun. 2016;7:10252 pubmed publisher
|
- western blot; human; fig 4
| Long J, Giotis E, Moncorgé O, Frise R, Mistry B, James J, et al. Species difference in ANP32A underlies influenza A virus polymerase host restriction. Nature. 2016;529:101-4 pubmed publisher
|
| Yasuma K, Yasunaga J, Takemoto K, Sugata K, Mitobe Y, Takenouchi N, et al. HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT). PLoS Pathog. 2016;12:e1005372 pubmed publisher
|
- western blot; human; 1:8000; fig 4
| Lee S, Frattini V, Bansal M, Castano A, Sherman D, Hutchinson K, et al. An ID2-dependent mechanism for VHL inactivation in cancer. Nature. 2016;529:172-7 pubmed publisher
|
- immunohistochemistry; human; 1:50; fig e8
| Shu S, Lin C, He H, Witwicki R, Tabassum D, Roberts J, et al. Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer. Nature. 2016;529:413-417 pubmed publisher
|
- western blot; human; fig 1
| Kim T, Jin F, Shin S, Oh S, Lightfoot S, Grande J, et al. Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1. J Clin Invest. 2016;126:706-20 pubmed publisher
|
- immunoprecipitation; human; fig 4
| Yu C, Liang J, Li J, Lee Y, Chang B, Su C, et al. Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins. PLoS Pathog. 2015;11:e1005350 pubmed publisher
|
- immunoprecipitation; human; fig e1
| Zhao D, Gish G, Braunschweig U, Li Y, Ni Z, Schmitges F, et al. SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Nature. 2016;529:48-53 pubmed publisher
|
- immunocytochemistry; human; fig 6E
- western blot; human; fig 1A
| Ding X, Jiang W, Zhou P, Liu L, Wan X, Yuan X, et al. Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O-GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7). PLoS ONE. 2015;10:e0145023 pubmed publisher
|
- immunoprecipitation; mouse; fig 5
| Shi H, Wang Y, Li X, Zhan X, Tang M, Fina M, et al. NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component. Nat Immunol. 2016;17:250-8 pubmed publisher
|
- immunoprecipitation; human; fig 1
- western blot; human; fig 1
| Song H, Tao L, Chen C, Pan L, Hao J, Ni Y, et al. USP17-mediated deubiquitination and stabilization of HDAC2 in cigarette smoke extract-induced inflammation. Int J Clin Exp Pathol. 2015;8:10707-15 pubmed
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- immunoprecipitation; human; 1:1000; fig 3
- western blot; human; 1:1000; fig 3
| Bunda S, Burrell K, Heir P, Zeng L, Alamsahebpour A, Kano Y, et al. Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis. Nat Commun. 2015;6:8859 pubmed publisher
|
- western blot; human; 1:1000; fig 4
| Tollenaere M, Villumsen B, Blasius M, Nielsen J, Wagner S, Bartek J, et al. p38- and MK2-dependent signalling promotes stress-induced centriolar satellite remodelling via 14-3-3-dependent sequestration of CEP131/AZI1. Nat Commun. 2015;6:10075 pubmed publisher
|
- western blot; human; 1:2000; fig s1a
| Yan Y, Ollila S, Wong I, Vallenius T, Palvimo J, Vaahtomeri K, et al. SUMOylation of AMPKα1 by PIAS4 specifically regulates mTORC1 signalling. Nat Commun. 2015;6:8979 pubmed publisher
|
- immunoprecipitation; human; fig 2b
- western blot; human; fig 2b
| Stadhouders R, Cico A, Stephen T, Thongjuea S, Kolovos P, Baymaz H, et al. Control of developmentally primed erythroid genes by combinatorial co-repressor actions. Nat Commun. 2015;6:8893 pubmed publisher
|
- immunoprecipitation; Drosophila melanogaster; 1:4000; fig 3
- immunohistochemistry; Drosophila melanogaster; 1:500; fig 4
- western blot; Drosophila melanogaster; 1:4000; fig 3
- immunoprecipitation; African green monkey; 1:4000; fig 2
- western blot; African green monkey; 1:4000; fig 2
| Ukken F, Bruckner J, Weir K, Hope S, Sison S, Birschbach R, et al. BAR-SH3 sorting nexins are conserved interacting proteins of Nervous wreck that organize synapses and promote neurotransmission. J Cell Sci. 2016;129:166-77 pubmed publisher
|
- immunoprecipitation; human; fig 2a
| Vijayalingam S, Subramanian T, Zhao L, Chinnadurai G. The Cellular Protein Complex Associated with a Transforming Region of E1A Contains c-MYC. J Virol. 2016;90:1070-9 pubmed publisher
|
- chromatin immunoprecipitation; human; fig e7
- immunocytochemistry; human; fig e7
- western blot; human; fig e7
| Dou Z, Xu C, Donahue G, Shimi T, Pan J, Zhu J, et al. Autophagy mediates degradation of nuclear lamina. Nature. 2015;527:105-9 pubmed publisher
|
- western blot; mouse; fig 4
| Nady N, Gupta A, Ma Z, Swigut T, Koide A, Koide S, et al. ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formation. elife. 2015;4:e10150 pubmed publisher
|
- western blot; human; 1:2000
| Zhang T, Xu Y, Liu Y, Ye Y. gp78 functions downstream of Hrd1 to promote degradation of misfolded proteins of the endoplasmic reticulum. Mol Biol Cell. 2015;26:4438-50 pubmed publisher
|
- immunoprecipitation; human; fig 1c
- western blot; human; 1:2000; fig 1c
| Hu D, Gur M, Zhou Z, Gamper A, Hung M, Fujita N, et al. Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis. Nat Commun. 2015;6:8419 pubmed publisher
|
- immunoprecipitation; human; fig 5
| Guo Y, Feng W, Sy S, Huen M. ATM-dependent Phosphorylation of the Fanconi Anemia Protein PALB2 Promotes the DNA Damage Response. J Biol Chem. 2015;290:27545-56 pubmed publisher
|
- western blot; human; fig s7e
| Pelish H, Liau B, Nitulescu I, Tangpeerachaikul A, Poss Z, Da Silva D, et al. Mediator kinase inhibition further activates super-enhancer-associated genes in AML. Nature. 2015;526:273-276 pubmed publisher
|
- immunohistochemistry; mouse; fig 1d
| Maqdasy S, El Hajjaji F, Baptissart M, Viennois E, Oumeddour A, Brugnon F, et al. Identification of the Functions of Liver X Receptor-β in Sertoli Cells Using a Targeted Expression-Rescue Model. Endocrinology. 2015;156:4545-57 pubmed publisher
|
- western blot; human; 1:5000; fig 1
| Rao X, Duan X, Mao W, Li X, Li Z, Li Q, et al. O-GlcNAcylation of G6PD promotes the pentose phosphate pathway and tumor growth. Nat Commun. 2015;6:8468 pubmed publisher
|
- immunoprecipitation; human; fig 4e
| Hilton B, Li Z, Musich P, Wang H, Cartwright B, SERRANO M, et al. ATR Plays a Direct Antiapoptotic Role at Mitochondria, which Is Regulated by Prolyl Isomerase Pin1. Mol Cell. 2015;60:35-46 pubmed publisher
|
- western blot; mouse; 1:1000; fig 1
| Anderson K, Russell A, Foletta V. NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide - But not palmitate-induced toxicity. FEBS Open Bio. 2015;5:668-81 pubmed publisher
|
- western blot; human; 1:1000; fig 1c
| Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, et al. The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway. PLoS Genet. 2015;11:e1005503 pubmed publisher
|
- immunoprecipitation; human; fig 1b
| Zhu J, Sammons M, Donahue G, Dou Z, Vedadi M, Getlik M, et al. Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth. Nature. 2015;525:206-11 pubmed publisher
|
- immunohistochemistry; Caenorhabditis elegans; 1:200; fig 5
| Chen Y, Bharill S, Isacoff E, Chalfie M. Subunit composition of a DEG/ENaC mechanosensory channel of Caenorhabditis elegans. Proc Natl Acad Sci U S A. 2015;112:11690-5 pubmed publisher
|
- immunocytochemistry; S. cerevisiae; 1:100; fig s1a
| JoviÄić A, Mertens J, Boeynaems S, Bogaert E, Chai N, Yamada S, et al. Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS. Nat Neurosci. 2015;18:1226-9 pubmed publisher
|
- western blot; mouse; fig 3
| Wang J, Zhang Y, Hou J, Qian X, Zhang H, Zhang Z, et al. Ube2s regulates Sox2 stability and mouse ES cell maintenance. Cell Death Differ. 2016;23:393-404 pubmed publisher
|
- immunoprecipitation; human; fig 1e
- western blot; human; fig 1e
| Torres M, Pandita R, Kulak O, Kumar R, Formstecher E, Horikoshi N, et al. Role of the Exocyst Complex Component Sec6/8 in Genomic Stability. Mol Cell Biol. 2015;35:3633-45 pubmed publisher
|
- western blot; human; fig 1
| Steingruber M, Socher E, Hutterer C, Webel R, Bergbrede T, Lenac T, et al. The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase Domain. Viruses. 2015;7:4582-601 pubmed publisher
|
- immunoprecipitation; human; fig 3
| Thandapani P, Song J, Gandin V, Cai Y, Rouleau S, Garant J, et al. Aven recognition of RNA G-quadruplexes regulates translation of the mixed lineage leukemia protooncogenes. elife. 2015;4: pubmed publisher
|
- western blot; Drosophila melanogaster; 1:10,000
| Chakraborty R, Li Y, Zhou L, Golic K. Corp Regulates P53 in Drosophila melanogaster via a Negative Feedback Loop. PLoS Genet. 2015;11:e1005400 pubmed publisher
|
- western blot; human; fig 5f
| Phan L, Chou P, Velazquez Torres G, Samudio I, Parreno K, Huang Y, et al. The cell cycle regulator 14-3-3σ opposes and reverses cancer metabolic reprogramming. Nat Commun. 2015;6:7530 pubmed publisher
|
- western blot; human; 1:5000; fig 1
| Chen S, Okada M, Nakato R, Izumi K, Bando M, Shirahige K. The Deubiquitinating Enzyme USP7 Regulates Androgen Receptor Activity by Modulating Its Binding to Chromatin. J Biol Chem. 2015;290:21713-23 pubmed publisher
|
- immunoprecipitation; human; fig 2h
- western blot; human; fig 2d
| Shi J, Liu Y, Xu X, Zhang W, Yu T, Jia J, et al. Deubiquitinase USP47/UBP64E Regulates β-Catenin Ubiquitination and Degradation and Plays a Positive Role in Wnt Signaling. Mol Cell Biol. 2015;35:3301-11 pubmed publisher
|
- western blot; rat; fig 6a
| Bollimpelli V, Kondapi A. Enriched rat primary ventral mesencephalic neurons as an in-vitro culture model. Neuroreport. 2015;26:728-34 pubmed publisher
|
- western blot; rat; fig 6a
| Pedros C, Gaud G, Bernard I, Kassem S, Chabod M, Lagrange D, et al. An Epistatic Interaction between Themis1 and Vav1 Modulates Regulatory T Cell Function and Inflammatory Bowel Disease Development. J Immunol. 2015;195:1608-16 pubmed publisher
|
- western blot; human; fig 6
| Xu Q, Zhang Y, Wei Q, Huang Y, Li Y, Ling K, et al. BBS4 and BBS5 show functional redundancy in the BBSome to regulate the degradative sorting of ciliary sensory receptors. Sci Rep. 2015;5:11855 pubmed publisher
|
- western blot; human; 1:1000; fig 5
| Çelik H, Sajwan K, Selvanathan S, Marsh B, Pai A, Kont Y, et al. Ezrin Binds to DEAD-Box RNA Helicase DDX3 and Regulates Its Function and Protein Level. Mol Cell Biol. 2015;35:3145-62 pubmed publisher
|
- immunohistochemistry; mouse; 1:6000; fig s1a
- western blot; human; fig s1b
| Tindi J, Chávez A, Cvejic S, Calvo Ochoa E, Castillo P, Jordan B. ANKS1B Gene Product AIDA-1 Controls Hippocampal Synaptic Transmission by Regulating GluN2B Subunit Localization. J Neurosci. 2015;35:8986-96 pubmed publisher
|
- western blot; human; fig 1D
| Amente S, Milazzo G, Sorrentino M, Ambrosio S, Di Palo G, Lania L, et al. Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively repress tumor suppressor genes in neuroblastoma. Oncotarget. 2015;6:14572-83 pubmed
|
- immunohistochemistry; mouse; 1:6000; fig s1a
- western blot; human; fig s1b
| Omori Y, Chaya T, Yoshida S, Irie S, Tsujii T, Furukawa T. Identification of G Protein-Coupled Receptors (GPCRs) in Primary Cilia and Their Possible Involvement in Body Weight Control. PLoS ONE. 2015;10:e0128422 pubmed publisher
|
- immunoprecipitation; human; fig 1
| Lu H, Li Z, Zhang W, Schulze Gahmen U, Xue Y, Zhou Q. Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription. Nucleic Acids Res. 2015;43:5868-79 pubmed publisher
|
- immunohistochemistry; human; 1:500; fig 2
| Monaghan R, Barnes R, Fisher K, Andreou T, Rooney N, Poulin G, et al. A nuclear role for the respiratory enzyme CLK-1 in regulating mitochondrial stress responses and longevity. Nat Cell Biol. 2015;17:782-92 pubmed publisher
|
- immunoprecipitation; human
| Grow E, Flynn R, CHAVEZ S, Bayless N, Wossidlo M, Wesche D, et al. Intrinsic retroviral reactivation in human preimplantation embryos and pluripotent cells. Nature. 2015;522:221-5 pubmed publisher
|
- immunoprecipitation; mouse; 1:5000; fig 7
- western blot; mouse; 1:5000; fig 7
| Stemig M, Astelford K, Emery A, Cho J, Allen B, Huang T, et al. Deletion of histone deacetylase 7 in osteoclasts decreases bone mass in mice by interactions with MITF. PLoS ONE. 2015;10:e0123843 pubmed publisher
|
- ChIP-Seq; mouse; 1:2000; fig 5
| Alexander J, Hota S, He D, Thomas S, Ho L, Pennacchio L, et al. Brg1 modulates enhancer activation in mesoderm lineage commitment. Development. 2015;142:1418-30 pubmed publisher
|
- western blot; human; fig 6
| Hendriks I, Treffers L, Verlaan de Vries M, Olsen J, Vertegaal A. SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage. Cell Rep. 2015;10:1778-1791 pubmed publisher
|
- western blot; human; 1:1000; fig 1,2,3,4,5,6,7
| Desantis A, Bruno T, Catena V, De Nicola F, Goeman F, Iezzi S, et al. Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy. EMBO J. 2015;34:1214-30 pubmed publisher
|
- western blot; human; 1:4000; fig s4
| Conn S, Pillman K, Toubia J, Conn V, Salmanidis M, Phillips C, et al. The RNA binding protein quaking regulates formation of circRNAs. Cell. 2015;160:1125-34 pubmed publisher
|
- immunocytochemistry; human; 1:1000; fig 1
- western blot; human; 1:1000; fig 3
| Kocyłowski M, Rey A, Stewart G, Halazonetis T. Ubiquitin-H2AX fusions render 53BP1 recruitment to DNA damage sites independent of RNF8 or RNF168. Cell Cycle. 2015;14:1748-58 pubmed publisher
|
- chromatin immunoprecipitation; mouse; fig s9
- immunoprecipitation; human; 1:50; fig 4
| Fillmore C, Xu C, Desai P, Berry J, Rowbotham S, Lin Y, et al. EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors. Nature. 2015;520:239-42 pubmed publisher
|
- immunohistochemistry - frozen section; mouse; 1:250; fig 3
| Orr A, Hsiao E, Wang M, Ho K, Kim D, Wang X, et al. Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory. Nat Neurosci. 2015;18:423-34 pubmed publisher
|
- western blot; human; 1:2000; fig 2
| Xu J, Eriksson S, Cebula M, Sandalova T, Hedström E, Pader I, et al. The conserved Trp114 residue of thioredoxin reductase 1 has a redox sensor-like function triggering oligomerization and crosslinking upon oxidative stress related to cell death. Cell Death Dis. 2015;6:e1616 pubmed publisher
|
| Kanazawa I, Canaff L, Abi Rafeh J, Angrula A, Li J, Riddle R, et al. Osteoblast menin regulates bone mass in vivo. J Biol Chem. 2015;290:3910-24 pubmed publisher
|
- immunoprecipitation; mouse; 1:500-1:1000; fig 7
| Imajo M, Ebisuya M, Nishida E. Dual role of YAP and TAZ in renewal of the intestinal epithelium. Nat Cell Biol. 2015;17:7-19 pubmed publisher
|
| Ling X, Xu C, Fan C, Zhong K, Li F, Wang X. FL118 induces p53-dependent senescence in colorectal cancer cells by promoting degradation of MdmX. Cancer Res. 2014;74:7487-97 pubmed publisher
|
- western blot; human; fig 4
| Zou J, Zhang D, Qin G, Chen X, Wang H, Zhang D. BRCA1 and FancJ cooperatively promote interstrand crosslinker induced centrosome amplification through the activation of polo-like kinase 1. Cell Cycle. 2014;13:3685-97 pubmed publisher
|
- immunoprecipitation; mouse; fig 4
- western blot; mouse; fig 4
| Bittencourt D, Lee B, Gao L, Gerke D, Stallcup M. Role of distinct surfaces of the G9a ankyrin repeat domain in histone and DNA methylation during embryonic stem cell self-renewal and differentiation. Epigenetics Chromatin. 2014;7:27 pubmed publisher
|
- immunoprecipitation; human; fig 8
- immunocytochemistry; human; 1:200; fig 7
- western blot; human; 1:3000; fig 8
| Liu Y, Luo S, He S, Zhang M, Wang P, Li C, et al. Tetherin restricts HSV-2 release and is counteracted by multiple viral glycoproteins. Virology. 2015;475:96-109 pubmed publisher
|
- immunocytochemistry; human; 1:5000
- western blot; human; 1:1000
| Kitai Y, Takeuchi O, Kawasaki T, Ori D, Sueyoshi T, Murase M, et al. Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B. J Biol Chem. 2015;290:1269-80 pubmed publisher
|
- immunoprecipitation; human; fig 1
- western blot; human; 1:1000; fig 1
| Ma B, Chen Y, Chen L, Cheng H, Mu C, Li J, et al. Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase. Nat Cell Biol. 2015;17:95-103 pubmed publisher
|
- western blot; mouse; 1:3000
| Bongers K, Fox D, Kunkel S, Stebounova L, Murry D, Pufall M, et al. Spermine oxidase maintains basal skeletal muscle gene expression and fiber size and is strongly repressed by conditions that cause skeletal muscle atrophy. Am J Physiol Endocrinol Metab. 2015;308:E144-58 pubmed publisher
|
- western blot; mouse; 1:500; fig 7
| Huang L, Carney J, Cardona D, Counter C. Decreased tumorigenesis in mice with a Kras point mutation at C118. Nat Commun. 2014;5:5410 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Eifler T, Shao W, Bartholomeeusen K, Fujinaga K, Jäger S, Johnson J, et al. Cyclin-dependent kinase 12 increases 3' end processing of growth factor-induced c-FOS transcripts. Mol Cell Biol. 2015;35:468-78 pubmed publisher
|
- immunoprecipitation; human; 1:5000; fig s8
| Izawa D, Pines J. The mitotic checkpoint complex binds a second CDC20 to inhibit active APC/C. Nature. 2015;517:631-4 pubmed publisher
|
- chromatin immunoprecipitation; mouse; fig 4
- western blot; mouse; fig 4
| Shi X, Zhang Z, Zhan X, Cao M, Satoh T, Akira S, et al. An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth. Nat Commun. 2014;5:5425 pubmed publisher
|
- immunoprecipitation; human
- western blot; human; fig 4
| Wang Y, Yang Y, Wu S, Pan S, Zhou C, Ma Y, et al. p32 is a novel target for viral protein ICP34.5 of herpes simplex virus type 1 and facilitates viral nuclear egress. J Biol Chem. 2014;289:35795-805 pubmed publisher
|
- immunoprecipitation; mouse; fig 8
- western blot; mouse; fig 8
| Liang N, Zhang C, Dill P, Panasyuk G, Pion D, Koka V, et al. Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex. J Exp Med. 2014;211:2249-63 pubmed publisher
|
- immunoprecipitation; human
| Tsai K, Chan L, Gibeault R, Conn K, Dheekollu J, Domsic J, et al. Viral reprogramming of the Daxx histone H3.3 chaperone during early Epstein-Barr virus infection. J Virol. 2014;88:14350-63 pubmed publisher
|
- immunoprecipitation; human; 1:100
| Liang Y, Eng W, Colquhoun D, Dinglasan R, Graham D, Mahal L. Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. J Biol Chem. 2014;289:32526-37 pubmed publisher
|
- western blot; human; loading ...; fig 6a
| Merabova N, Sariyer I, Saribas A, Knezevic T, Gordon J, Turco M, et al. WW domain of BAG3 is required for the induction of autophagy in glioma cells. J Cell Physiol. 2015;230:831-41 pubmed publisher
|
- western blot; mouse; fig 2
| Han M, Hu Z, Chen C, Chen Y, Gucek M, Li Z, et al. Dysbindin-associated proteome in the p2 synaptosome fraction of mouse brain. J Proteome Res. 2014;13:4567-80 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| de Souza E, Meirelles G, Godoy B, Perez A, Smetana J, Doxsey S, et al. Characterization of the human NEK7 interactome suggests catalytic and regulatory properties distinct from those of NEK6. J Proteome Res. 2014;13:4074-90 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Putker M, Vos H, van Dorenmalen K, de Ruiter H, Duran A, Snel B, et al. Evolutionary acquisition of cysteines determines FOXO paralog-specific redox signaling. Antioxid Redox Signal. 2015;22:15-28 pubmed publisher
|
- immunoprecipitation; mouse
- immunocytochemistry; mouse
- western blot; mouse
- immunoprecipitation; human
- immunocytochemistry; human
- western blot; human
| Ro S, Semple I, Park H, Park H, Park H, Kim M, et al. Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1. FEBS J. 2014;281:3816-27 pubmed publisher
|
| Lo Sasso G, Ryu D, Mouchiroud L, Fernando S, Anderson C, Katsyuba E, et al. Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer. PLoS ONE. 2014;9:e102495 pubmed publisher
|
- immunoprecipitation; human
| Zhang P, Gao K, Tang Y, Jin X, An J, Yu H, et al. Destruction of DDIT3/CHOP protein by wild-type SPOP but not prostate cancer-associated mutants. Hum Mutat. 2014;35:1142-51 pubmed publisher
|
- immunocytochemistry; human
| O Rourke B, Gomez Ferreria M, Berk R, Hackl A, Nicholas M, O Rourke S, et al. Cep192 controls the balance of centrosome and non-centrosomal microtubules during interphase. PLoS ONE. 2014;9:e101001 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Choi Y, Kim Y, Jeong H, Jin Y, Yeo C, Lee K. Akt enhances Runx2 protein stability by regulating Smurf2 function during osteoblast differentiation. FEBS J. 2014;281:3656-66 pubmed publisher
|
- western blot; human; fig 2
| Hayashi A, Suenaga N, Shiomi Y, Nishitani H. PCNA-dependent ubiquitination of Cdt1 and p21 in mammalian cells. Methods Mol Biol. 2014;1170:367-82 pubmed publisher
|
- immunocytochemistry; mouse; 1:500; fig 5e
- western blot; mouse; 1:1000; fig s5b
| Cooper S, Dienstbier M, Hassan R, Schermelleh L, Sharif J, Blackledge N, et al. Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment. Cell Rep. 2014;7:1456-1470 pubmed publisher
|
| Lu H, Fang E, Sykora P, Kulikowicz T, Zhang Y, Becker K, et al. Senescence induced by RECQL4 dysfunction contributes to Rothmund-Thomson syndrome features in mice. Cell Death Dis. 2014;5:e1226 pubmed publisher
|
- immunocytochemistry; human; 1:500
| Hans F, Fiesel F, Strong J, J ckel S, Rasse T, Geisler S, et al. UBE2E ubiquitin-conjugating enzymes and ubiquitin isopeptidase Y regulate TDP-43 protein ubiquitination. J Biol Chem. 2014;289:19164-79 pubmed publisher
|
- western blot; Xenopus laevis; 0.5 ug/ml
| Kang Q, Srividhya J, Ipe J, Pomerening J. Evidence toward a dual phosphatase mechanism that restricts Aurora A (Thr-295) phosphorylation during the early embryonic cell cycle. J Biol Chem. 2014;289:17480-96 pubmed publisher
|
- flow cytometry; human; 1:50000
- immunoprecipitation; human; 1:50000
- western blot; human; 1:50000
| van de Weijer M, Bassik M, Luteijn R, Voorburg C, Lohuis M, Kremmer E, et al. A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation. Nat Commun. 2014;5:3832 pubmed publisher
|
- immunocytochemistry; human
| Vidi P, Liu J, Salles D, Jayaraman S, Dorfman G, Gray M, et al. NuMA promotes homologous recombination repair by regulating the accumulation of the ISWI ATPase SNF2h at DNA breaks. Nucleic Acids Res. 2014;42:6365-79 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Cipriano R, Miskimen K, Bryson B, Foy C, Bartel C, Jackson M. Conserved oncogenic behavior of the FAM83 family regulates MAPK signaling in human cancer. Mol Cancer Res. 2014;12:1156-65 pubmed publisher
|
- immunocytochemistry; human
| Kerdivel G, Boudot A, Habauzit D, Percevault F, Demay F, Pakdel F, et al. Activation of the MKL1/actin signaling pathway induces hormonal escape in estrogen-responsive breast cancer cell lines. Mol Cell Endocrinol. 2014;390:34-44 pubmed publisher
|
- western blot; mouse; 1:5000
| Okuda H, Tatsumi K, Horii Hayashi N, Morita S, Okuda Yamamoto A, Imaizumi K, et al. OASIS regulates chondroitin 6-O-sulfotransferase 1 gene transcription in the injured adult mouse cerebral cortex. J Neurochem. 2014;130:612-25 pubmed publisher
|
| Havel J, Li Z, Cheng D, Peng J, Fu H. Nuclear PRAS40 couples the Akt/mTORC1 signaling axis to the RPL11-HDM2-p53 nucleolar stress response pathway. Oncogene. 2015;34:1487-98 pubmed publisher
|
- immunoprecipitation; mouse
- immunocytochemistry; mouse
- western blot; mouse
| Adeyemi R, Fuller M, Pintel D. Efficient parvovirus replication requires CRL4Cdt2-targeted depletion of p21 to prevent its inhibitory interaction with PCNA. PLoS Pathog. 2014;10:e1004055 pubmed publisher
|
- immunocytochemistry; mouse
| Vreeland A, Yu S, Levi L, de Barros Rossetto D, Noy N. Transcript stabilization by the RNA-binding protein HuR is regulated by cellular retinoic acid-binding protein 2. Mol Cell Biol. 2014;34:2135-46 pubmed publisher
|
- chromatin immunoprecipitation; human
- immunoprecipitation; human
- immunohistochemistry; human; 1:1000
- western blot; human; 1:1000
| Rennoll S, Scott S, Yochum G. Targeted repression of AXIN2 and MYC gene expression using designer TALEs. Biochem Biophys Res Commun. 2014;446:1120-5 pubmed publisher
|
- immunoprecipitation; mouse
- western blot; mouse
| Huang Y, Liu H, Li S, Tang Y, Wei B, Yu H, et al. MAVS-MKK7-JNK2 defines a novel apoptotic signaling pathway during viral infection. PLoS Pathog. 2014;10:e1004020 pubmed publisher
|
| Wang Q, Shen B, Chen L, Zheng P, Feng H, Hao Q, et al. Extracellular calumenin suppresses ERK1/2 signaling and cell migration by protecting fibulin-1 from MMP-13-mediated proteolysis. Oncogene. 2015;34:1006-18 pubmed publisher
|
- immunocytochemistry; human; 1:400
| Justa Schuch D, Moller U, Geiss Friedlander R. The amino terminus extension in the long dipeptidyl peptidase 9 isoform contains a nuclear localization signal targeting the active peptidase to the nucleus. Cell Mol Life Sci. 2014;71:3611-26 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Matthess Y, Raab M, Knecht R, Becker S, Strebhardt K. Sequential Cdk1 and Plk1 phosphorylation of caspase-8 triggers apoptotic cell death during mitosis. Mol Oncol. 2014;8:596-608 pubmed publisher
|
- immunocytochemistry; human
| Salvi M, Raiborg C, Hanson P, Campsteijn C, Stenmark H, Pinna L. CK2 involvement in ESCRT-III complex phosphorylation. Arch Biochem Biophys. 2014;545:83-91 pubmed publisher
|
- western blot; human; fig 1
| Aida K, Hayashi H, Inamura K, Mizuno T, Sugiyama Y. Differential roles of ubiquitination in the degradation mechanism of cell surface-resident bile salt export pump and multidrug resistance-associated protein 2. Mol Pharmacol. 2014;85:482-91 pubmed publisher
|
- western blot; human; 1:1000
| Annibaldi A, Heulot M, Martinou J, Widmann C. TAT-RasGAP317-326-mediated tumor cell death sensitization can occur independently of Bax and Bak. Apoptosis. 2014;19:719-33 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Zhang W, Ji W, Liu X, Ouyang G, Xiao W. ELL inhibits E2F1 transcriptional activity by enhancing E2F1 deacetylation via recruitment of histone deacetylase 1. Mol Cell Biol. 2014;34:765-75 pubmed publisher
|
- immunocytochemistry; African green monkey
- western blot; mouse
| Brot S, Auger C, Bentata R, Rogemond V, Ménigoz S, Chounlamountri N, et al. Collapsin response mediator protein 5 (CRMP5) induces mitophagy, thereby regulating mitochondrion numbers in dendrites. J Biol Chem. 2014;289:2261-76 pubmed publisher
|
- immunohistochemistry - frozen section; Xenopus laevis
| Chu C, Gerstenzang E, Ossipova O, Sokol S. Lulu regulates Shroom-induced apical constriction during neural tube closure. PLoS ONE. 2013;8:e81854 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Kriz V, Pospichalova V, Masek J, Kilander M, Slavík J, Tanneberger K, et al. ?-arrestin promotes Wnt-induced low density lipoprotein receptor-related protein 6 (Lrp6) phosphorylation via increased membrane recruitment of Amer1 protein. J Biol Chem. 2014;289:1128-41 pubmed publisher
|
- immunoprecipitation; human
- immunocytochemistry; human
- western blot; human; fig 2
| Liu X, Xiao W, Wang X, Li Y, Han J, Li Y. The p38-interacting protein (p38IP) regulates G2/M progression by promoting ?-tubulin acetylation via inhibiting ubiquitination-induced degradation of the acetyltransferase GCN5. J Biol Chem. 2013;288:36648-61 pubmed publisher
|
- immunoprecipitation; human
- immunocytochemistry; human
| Sharma N, Zhu Q, Wani G, He J, Wang Q, Wani A. USP3 counteracts RNF168 via deubiquitinating H2A and ?H2AX at lysine 13 and 15. Cell Cycle. 2014;13:106-14 pubmed publisher
|
- western blot; mouse; 1:2000
| Evans C, Cook S, Coleman M, Gilley J. MEK inhibitor U0126 reverses protection of axons from Wallerian degeneration independently of MEK-ERK signaling. PLoS ONE. 2013;8:e76505 pubmed publisher
|
- immunocytochemistry; human; fig 2b
| Hashizume C, Kobayashi A, Wong R. Down-modulation of nucleoporin RanBP2/Nup358 impaired chromosomal alignment and induced mitotic catastrophe. Cell Death Dis. 2013;4:e854 pubmed publisher
|
- western blot; fission yeast
| DeGennaro C, Alver B, Marguerat S, Stepanova E, Davis C, Bähler J, et al. Spt6 regulates intragenic and antisense transcription, nucleosome positioning, and histone modifications genome-wide in fission yeast. Mol Cell Biol. 2013;33:4779-92 pubmed publisher
|
- immunocytochemistry; human
- western blot; human
| Berndt A, Wilkinson K, Heimann M, Bishop P, Henley J. In vivo characterization of the properties of SUMO1-specific monobodies. Biochem J. 2013;456:385-95 pubmed publisher
|
- immunoprecipitation; human
- western blot; human; fig 3
| Verma S, Cai Q, Kreider E, Lu J, Robertson E. Comprehensive analysis of LANA interacting proteins essential for viral genome tethering and persistence. PLoS ONE. 2013;8:e74662 pubmed publisher
|
| Ahmed S, Prigent S. A nuclear export signal and oxidative stress regulate ShcD subcellular localisation: a potential role for ShcD in the nucleus. Cell Signal. 2014;26:32-40 pubmed publisher
|
- immunoprecipitation; human
| Shats I, Gatza M, Liu B, Angus S, You L, Nevins J. FOXO transcription factors control E2F1 transcriptional specificity and apoptotic function. Cancer Res. 2013;73:6056-67 pubmed publisher
|
- immunocytochemistry; mouse; 1:1000
- immunocytochemistry; human; 1:1000
| Wang C, Low W, Liu A, Wang B. Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis. J Biol Chem. 2013;288:29518-29 pubmed publisher
|
| Kumar M, Allison D, Baranova N, Wamsley J, Katz A, Bekiranov S, et al. NF-?B regulates mesenchymal transition for the induction of non-small cell lung cancer initiating cells. PLoS ONE. 2013;8:e68597 pubmed publisher
|
- immunoprecipitation; human; 1:200-1:500; fig 1
| Gurkar A, Chu K, Raj L, Bouley R, Lee S, Kim Y, et al. Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress. Nat Commun. 2013;4:2189 pubmed publisher
|
| Sy S, Jiang J, O W, Deng Y, Huen M. The ubiquitin specific protease USP34 promotes ubiquitin signaling at DNA double-strand breaks. Nucleic Acids Res. 2013;41:8572-80 pubmed publisher
|
- immunocytochemistry; human
| Chandra S, Priyadarshini R, Madhavan V, Tikoo S, Hussain M, Mudgal R, et al. Enhancement of c-Myc degradation by BLM helicase leads to delayed tumor initiation. J Cell Sci. 2013;126:3782-95 pubmed publisher
|
- immunoprecipitation; human
| Wei Q, Li J, Liu T, Tong X, Ye X. Phosphorylation of minichromosome maintenance protein 7 (MCM7) by cyclin/cyclin-dependent kinase affects its function in cell cycle regulation. J Biol Chem. 2013;288:19715-25 pubmed publisher
|
| Boehlke C, Kotsis F, Buchholz B, Powelske C, Eckardt K, Walz G, et al. Kif3a guides microtubular dynamics, migration and lumen formation of MDCK cells. PLoS ONE. 2013;8:e62165 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Kubota S, Fukumoto Y, Aoyama K, Ishibashi K, Yuki R, Morinaga T, et al. Phosphorylation of KRAB-associated protein 1 (KAP1) at Tyr-449, Tyr-458, and Tyr-517 by nuclear tyrosine kinases inhibits the association of KAP1 and heterochromatin protein 1? (HP1?) with heterochromatin. J Biol Chem. 2013;288:17871-83 pubmed publisher
|
- chromatin immunoprecipitation; human
- immunoprecipitation; human
- immunocytochemistry; human
- western blot; human
| Zhou P, Wang Z, Yuan X, Zhou C, Liu L, Wan X, et al. Mixed lineage leukemia 5 (MLL5) protein regulates cell cycle progression and E2F1-responsive gene expression via association with host cell factor-1 (HCF-1). J Biol Chem. 2013;288:17532-43 pubmed publisher
|
| Yasuda Inoue M, Kuroki M, Ariumi Y. Distinct DDX DEAD-box RNA helicases cooperate to modulate the HIV-1 Rev function. Biochem Biophys Res Commun. 2013;434:803-8 pubmed publisher
|
- western blot; human; fig 4
| Tinnikov A, Samuels H. A novel cell lysis approach reveals that caspase-2 rapidly translocates from the nucleus to the cytoplasm in response to apoptotic stimuli. PLoS ONE. 2013;8:e61085 pubmed publisher
|
| Fu H, Sohail A, Valiathan R, Wasinski B, Kumarasiri M, Mahasenan K, et al. Shedding of discoidin domain receptor 1 by membrane-type matrix metalloproteinases. J Biol Chem. 2013;288:12114-29 pubmed publisher
|
| Murata Y, Constantine Paton M. Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway. J Neurosci. 2013;33:5040-52 pubmed publisher
|
- immunoprecipitation; mouse
| Zhang J, Twelvetrees A, Lazarus J, Blasier K, Yao X, Inamdar N, et al. Establishing a novel knock-in mouse line for studying neuronal cytoplasmic dynein under normal and pathologic conditions. Cytoskeleton (Hoboken). 2013;70:215-27 pubmed publisher
|
- immunocytochemistry; chicken; 1:500
| Wang Y, Dantas T, Lalor P, Dockery P, Morrison C. Promoter hijack reveals pericentrin functions in mitosis and the DNA damage response. Cell Cycle. 2013;12:635-46 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Dettmer U, Newman A, Luth E, Bartels T, Selkoe D. In vivo cross-linking reveals principally oligomeric forms of ?-synuclein and ?-synuclein in neurons and non-neural cells. J Biol Chem. 2013;288:6371-85 pubmed publisher
|
- western blot; chicken
- immunoprecipitation; human
- western blot; human; fig s10
| Moreno Garcia M, Sommer K, Rincón Arano H, Brault M, Ninomiya Tsuji J, Matesic L, et al. Kinase-independent feedback of the TAK1/TAB1 complex on BCL10 turnover and NF-?B activation. Mol Cell Biol. 2013;33:1149-63 pubmed publisher
|
- immunohistochemistry - frozen section; mouse
| Deguchi K, Nagamatsu G, Miyachi H, Kato Y, Morita S, Kimura H, et al. Posttranscriptional regulation of histone lysine methyltransferase GLP in embryonic male mouse germ cells. Biol Reprod. 2013;88:36 pubmed publisher
|
| Morlando M, Dini Modigliani S, Torrelli G, Rosa A, Di Carlo V, Caffarelli E, et al. FUS stimulates microRNA biogenesis by facilitating co-transcriptional Drosha recruitment. EMBO J. 2012;31:4502-10 pubmed publisher
|
- immunocytochemistry; African green monkey; 1:2000
- western blot; African green monkey; 1:4000
| Varco Merth B, Mirza K, Alzhanov D, Chia D, Rotwein P. Biochemical characterization of diverse Stat5b-binding enhancers that mediate growth hormone-activated insulin-like growth factor-I gene transcription. PLoS ONE. 2012;7:e50278 pubmed publisher
|
- immunoprecipitation; human
- immunoprecipitation; mouse
| Wang C, Kao Y, Lai P, Chen W, Chung B. Steroidogenic factor 1 (NR5A1) maintains centrosome homeostasis in steroidogenic cells by restricting centrosomal DNA-dependent protein kinase activation. Mol Cell Biol. 2013;33:476-84 pubmed publisher
|
| Journo C, Bonnet A, Favre Bonvin A, Turpin J, Vinera J, C t E, et al. Human T cell leukemia virus type 2 tax-mediated NF-?B activation involves a mechanism independent of Tax conjugation to ubiquitin and SUMO. J Virol. 2013;87:1123-36 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Katoh H, Okamoto T, Fukuhara T, Kambara H, Morita E, Mori Y, et al. Japanese encephalitis virus core protein inhibits stress granule formation through an interaction with Caprin-1 and facilitates viral propagation. J Virol. 2013;87:489-502 pubmed publisher
|
- immunocytochemistry; mouse
| Magli A, Schnettler E, Rinaldi F, Bremer P, Perlingeiro R. Functional dissection of Pax3 in paraxial mesoderm development and myogenesis. Stem Cells. 2013;31:59-70 pubmed publisher
|
- immunoprecipitation; human
| Yeung F, Chung E, Guess M, Bell M, Leinwand L. Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos. Nucleic Acids Res. 2012;40:7303-18 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Zhou F, Zhang X, van Dam H, Ten Dijke P, Huang H, Zhang L. Ubiquitin-specific protease 4 mitigates Toll-like/interleukin-1 receptor signaling and regulates innate immune activation. J Biol Chem. 2012;287:11002-10 pubmed publisher
|
- western blot; human
- western blot; mouse
| Tanida I, Yamasaki M, Komatsu M, Ueno T. The FAP motif within human ATG7, an autophagy-related E1-like enzyme, is essential for the E2-substrate reaction of LC3 lipidation. Autophagy. 2012;8:88-97 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Heinz L, Rebsamen M, Rossi D, Staehli F, Schroder K, Quadroni M, et al. The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade. Cell Death Differ. 2012;19:722-31 pubmed publisher
|
- western blot; human
- western blot; Caenorhabditis elegans
| Sun L, Wang M, Lv Z, Yang N, Liu Y, Bao S, et al. Structural insights into protein arginine symmetric dimethylation by PRMT5. Proc Natl Acad Sci U S A. 2011;108:20538-43 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Wang Z, Zhang Y, Zhang S, Guo Q, Tan Y, Wang X, et al. DJ-1 can inhibit microtubule associated protein 1 B formed aggregates. Mol Neurodegener. 2011;6:38 pubmed publisher
|
- immunoprecipitation; Saccharomycetales
| Chandrasekharan M, Huang F, Sun Z. Decoding the trans-histone crosstalk: methods to analyze H2B ubiquitination, H3 methylation and their regulatory factors. Methods. 2011;54:304-14 pubmed publisher
|
| Lovric M, Hawkins C. TRAIL treatment provokes mutations in surviving cells. Oncogene. 2010;29:5048-60 pubmed publisher
|
- immunocytochemistry; human; 1:1000
- western blot; human; 1:10000
| Roblek M, Schüchner S, Huber V, Ollram K, Vlcek Vesely S, Foisner R, et al. Monoclonal antibodies specific for disease-associated point-mutants: lamin A/C R453W and R482W. PLoS ONE. 2010;5:e10604 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Nayak A, Glöckner Pagel J, Vaeth M, Schumann J, Buttmann M, Bopp T, et al. Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and interleukin-2 repression by histone deacetylase. J Biol Chem. 2009;284:10935-46 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Zhao Y, Lang G, Ito S, Bonnet J, Metzger E, Sawatsubashi S, et al. A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing. Mol Cell. 2008;29:92-101 pubmed publisher
|
- immunoprecipitation; human
- western blot; human
| Mayor A, Martinon F, De Smedt T, Petrilli V, Tschopp J. A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses. Nat Immunol. 2007;8:497-503 pubmed
|
| Hu H, Ji Q, Song M, Ren J, Liu Z, Wang Z, et al. ZKSCAN3 counteracts cellular senescence by stabilizing heterochromatin. Nucleic Acids Res. 2020;48:6001-6018 pubmed publisher
|
| Hu D, Chen H, Lou L, Zhang H, Yang G. SKA3 promotes lung adenocarcinoma metastasis through the EGFR-PI3K-Akt axis. Biosci Rep. 2020;40: pubmed publisher
|
| Lu M, Zhang Z, Xue M, Zhao B, Harder O, Li A, et al. N6-methyladenosine modification enables viral RNA to escape recognition by RNA sensor RIG-I. Nat Microbiol. 2020;5:584-598 pubmed publisher
|
| Alexandrova J, Piñeiro D, Jukes Jones R, Mordue R, Stoneley M, Willis A. Full-length NF-κB repressing factor contains an XRN2 binding domain. Biochem J. 2020;477:773-786 pubmed publisher
|
| Sheynov A, Tatarskiy V, Tatarskiy E, Nabirochkina E, Georgieva S, Soshnikova N. The sequential phosphorylation of PHF10 subunit of the PBAF chromatin-remodeling complex determines different properties of the PHF10 isoforms. Biol Open. 2020;9: pubmed publisher
|
| Wan L, Chong S, Xuan F, Liang A, Cui X, Gates L, et al. Impaired cell fate through gain-of-function mutations in a chromatin reader. Nature. 2020;577:121-126 pubmed publisher
|
| Bhargava V, Goldstein C, Russell L, Xu L, Ahmed M, Li W, et al. GCNA Preserves Genome Integrity and Fertility Across Species. Dev Cell. 2020;52:38-52.e10 pubmed publisher
|
| Natarajan N, Foresti O, Wendrich K, Stein A, Carvalho P. Quality Control of Protein Complex Assembly by a Transmembrane Recognition Factor. Mol Cell. 2020;77:108-119.e9 pubmed publisher
|
| Kim K, Lee D, Park S, Jo S, Ku B, Park S, et al. Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera. Sci Rep. 2019;9:19654 pubmed publisher
|
| Smolko C, Janes K. An ultrasensitive fiveplex activity assay for cellular kinases. Sci Rep. 2019;9:19409 pubmed publisher
|
| Fifield B, Qemo I, Kirou E, Cardiff R, Porter L. The atypical cyclin-like protein Spy1 overrides p53-mediated tumour suppression and promotes susceptibility to breast tumourigenesis. Breast Cancer Res. 2019;21:140 pubmed publisher
|
| Koh C, Goh Y, Goh W. Atlas of quantitative single-base-resolution N6-methyl-adenine methylomes. Nat Commun. 2019;10:5636 pubmed publisher
|
| Wang L, Tan T, Durbin A, Zimmerman M, Abraham B, Tan S, et al. ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry. Nat Commun. 2019;10:5622 pubmed publisher
|
| Woo Y, Kim S, Suh B, Kwak Y, Jung H, Nhung T, et al. Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis. elife. 2019;8: pubmed publisher
|
| Jia J, Claude Taupin A, Gu Y, Choi S, Peters R, Bissa B, et al. Galectin-3 Coordinates a Cellular System for Lysosomal Repair and Removal. Dev Cell. 2019;: pubmed publisher
|
| Chao C, Gutiérrez Vázquez C, Rothhammer V, Mayo L, Wheeler M, Tjon E, et al. Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS. Cell. 2019;179:1483-1498.e22 pubmed publisher
|
| Svendsen J, Reed K, Vijayasarathy T, Montgomery B, Tucci R, Brown K, et al. henn-1/HEN1 Promotes Germline Immortality in Caenorhabditis elegans. Cell Rep. 2019;29:3187-3199.e4 pubmed publisher
|
| Elder E, Krishna B, Williamson J, Lim E, Poole E, Sedikides G, et al. Interferon-Responsive Genes Are Targeted during the Establishment of Human Cytomegalovirus Latency. MBio. 2019;10: pubmed publisher
|
| Sonntag T, Moresco J, Yates J, Montminy M. The KLDpT activation loop motif is critical for MARK kinase activity. PLoS ONE. 2019;14:e0225727 pubmed publisher
|
| Boone P, Rochelle L, Ginzel J, Lubkov V, Roberts W, Nicholls P, et al. A cancer rainbow mouse for visualizing the functional genomics of oncogenic clonal expansion. Nat Commun. 2019;10:5490 pubmed publisher
|
| Dudek A, Zabaleta N, Zinn E, Pillay S, Zengel J, Porter C, et al. GPR108 Is a Highly Conserved AAV Entry Factor. Mol Ther. 2019;: pubmed publisher
|
| Chappidi N, Nascakova Z, Boleslavska B, Zellweger R, Isik E, Andrs M, et al. Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops. Mol Cell. 2019;: pubmed publisher
|
| Saito K, Iioka H, Maruyama S, Sumardika I, Sakaguchi M, Kondo E. PODXL1 promotes metastasis of the pancreatic ductal adenocarcinoma by activating the C5aR/C5a axis from the tumor microenvironment. Neoplasia. 2019;21:1121-1132 pubmed publisher
|
| Im D, Kim S, Chau G, Um S. Carbamazepine Enhances Adipogenesis by Inhibiting Wnt/β-catenin Expression. Cells. 2019;8: pubmed publisher
|
| Wang S, Crisman L, Miller J, Datta I, Gulbranson D, Tian Y, et al. Inducible Exoc7/Exo70 knockout reveals a critical role of the exocyst in insulin-regulated GLUT4 exocytosis. J Biol Chem. 2019;294:19988-19996 pubmed publisher
|
| Huang Y, Mouttet B, Warnatz H, Risch T, Rietmann F, Frommelt F, et al. The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability. Cancer Cell. 2019;36:630-644.e9 pubmed publisher
|
| Brosig A, Fuchs J, Ipek F, Kroon C, Schrötter S, Vadhvani M, et al. The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches. Cell Rep. 2019;29:2028-2040.e8 pubmed publisher
|
| Park S, Jeon P, Jun Y, Park J, Lee S, Lee S, et al. Monitoring LC3- or GABARAP-positive autophagic membranes using modified RavZ-based probes. Sci Rep. 2019;9:16593 pubmed publisher
|
| Belli M, Secchi C, Stupack D, Shimasaki S. FOXO1 Negates the Cooperative Action of FOXL2C134W and SMAD3 in CYP19 Expression in HGrC1 Cells by Sequestering SMAD3. J Endocr Soc. 2019;3:2064-2081 pubmed publisher
|
| Jia R, Bonifacino J. Negative regulation of autophagy by UBA6-BIRC6-mediated ubiquitination of LC3. elife. 2019;8: pubmed publisher
|
| Foster S, Hauser A, Vedel L, Strachan R, Huang X, Gavin A, et al. Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors. Cell. 2019;179:895-908.e21 pubmed publisher
|
| Chen T, Zhang B, Ziegenhals T, Prusty A, Fröhler S, Grimm C, et al. A missense mutation in SNRPE linked to non-syndromal microcephaly interferes with U snRNP assembly and pre-mRNA splicing. PLoS Genet. 2019;15:e1008460 pubmed publisher
|
| Xiang Q, Ju H, Nicholas J. USP7-Dependent Regulation of TRAF Activation and Signaling by a Viral Interferon Regulatory Factor Homologue. J Virol. 2019;: pubmed publisher
|
| Oprişoreanu A, Smith H, Arya S, Webster R, Zhong Z, Wehner D, et al. Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation. Cell Rep. 2019;29:1082-1098.e10 pubmed publisher
|
| Chen D, Hou Z, Jiang D, Zheng M, Li G, Zhang Y, et al. GILT restricts the cellular entry mediated by the envelope glycoproteins of SARS-CoV, Ebola virus and Lassa fever virus. Emerg Microbes Infect. 2019;8:1511-1523 pubmed publisher
|
| Arai H, Sato F, Yamamoto T, Woltjen K, Kiyonari H, Yoshimoto Y, et al. Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate. Cell Rep. 2019;29:603-616.e5 pubmed publisher
|
| Radzisheuskaya A, Shliaha P, Grinev V, Lorenzini E, Kovalchuk S, Shlyueva D, et al. PRMT5 methylome profiling uncovers a direct link to splicing regulation in acute myeloid leukemia. Nat Struct Mol Biol. 2019;26:999-1012 pubmed publisher
|
| Moriyama M, Koshiba T, Ichinohe T. Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses. Nat Commun. 2019;10:4624 pubmed publisher
|
| Buchwalter A, Schulte R, Tsai H, Capitanio J, Hetzer M. Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress. elife. 2019;8: pubmed publisher
|
| Smith E, Somma D, Kerrigan D, McIntyre Z, Cole J, Liang K, et al. The regulation of sequence specific NF-κB DNA binding and transcription by IKKβ phosphorylation of NF-κB p50 at serine 80. Nucleic Acids Res. 2019;47:11151-11163 pubmed publisher
|
| Suzuki H, Shibagaki Y, Hattori S, Matsuoka M. C9-ALS/FTD-linked proline-arginine dipeptide repeat protein associates with paraspeckle components and increases paraspeckle formation. Cell Death Dis. 2019;10:746 pubmed publisher
|
| Pantier R, Tatar T, Colby D, Chambers I. Endogenous epitope-tagging of Tet1, Tet2 and Tet3 identifies TET2 as a naïve pluripotency marker. Life Sci Alliance. 2019;2: pubmed publisher
|
| Guo L, Wang R, Zhang K, Yuan J, Wang J, Wang X, et al. A PINCH-1-Smurf1 signaling axis mediates mechano-regulation of BMPR2 and stem cell differentiation. J Cell Biol. 2019;218:3773-3794 pubmed publisher
|
| Hughes M, Hooftman A, Angiari S, Tummala P, Zaslona Z, Runtsch M, et al. Glutathione Transferase Omega-1 Regulates NLRP3 Inflammasome Activation through NEK7 Deglutathionylation. Cell Rep. 2019;29:151-161.e5 pubmed publisher
|
| Chen Y, Hao Q, Wang J, Li J, Huang C, Zhang Y, et al. Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53. Cell Death Dis. 2019;10:737 pubmed publisher
|
| Esposito M, Minopoli G, Esposito L, D Argenio V, Di Maggio F, Sasso E, et al. A Functional Analysis of the Unclassified Pro2767Ser BRCA2 Variant Reveals Its Potential Pathogenicity that Acts by Hampering DNA Binding and Homology-Mediated DNA Repair. Cancers (Basel). 2019;11: pubmed publisher
|
| Huang K, O Neill K, Li J, Zhou W, Han N, Pang X, et al. BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis. Cell Res. 2019;29:942-952 pubmed publisher
|
| Chao T, Zhang Q, Li Z, Tiwari S, Qin Y, Yau E, et al. The Long Noncoding RNA HEAL Regulates HIV-1 Replication through Epigenetic Regulation of the HIV-1 Promoter. MBio. 2019;10: pubmed publisher
|
| Taghbalout A, Du M, Jillette N, Rosikiewicz W, Rath A, Heinen C, et al. Enhanced CRISPR-based DNA demethylation by Casilio-ME-mediated RNA-guided coupling of methylcytosine oxidation and DNA repair pathways. Nat Commun. 2019;10:4296 pubmed publisher
|
| Jeng E, Bhadkamkar V, Ibe N, Gause H, Jiang L, Chan J, et al. Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen. Cell Host Microbe. 2019;26:551-563.e6 pubmed publisher
|
| Meng X, McGraw C, Wang W, Jing J, Yeh S, Wang L, et al. Neurexophilin4 is a selectively expressed α-neurexin ligand that modulates specific cerebellar synapses and motor functions. elife. 2019;8: pubmed publisher
|
| Ngo A, Shurtleff M, Popova K, Kulsuptrakul J, Weissman J, Puschnik A. The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins. elife. 2019;8: pubmed publisher
|
| Maghool S, Cooray N, Stroud D, Aragao D, Ryan M, Maher M. Structural and functional characterization of the mitochondrial complex IV assembly factor Coa6. Life Sci Alliance. 2019;2: pubmed publisher
|
| Thekkinghat A, Yadav K, Rangarajan P. Apolipoprotein L9 interacts with LC3/GABARAP and is a microtubule-associated protein with a widespread subcellular distribution. Biol Open. 2019;8: pubmed publisher
|
| Samir P, Kesavardhana S, Patmore D, Gingras S, Malireddi R, Karki R, et al. DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome. Nature. 2019;573:590-594 pubmed publisher
|
| Peter C, Saito A, Hasegawa Y, Tanaka Y, Nagpal M, Perez G, et al. In vivo epigenetic editing of Sema6a promoter reverses transcallosal dysconnectivity caused by C11orf46/Arl14ep risk gene. Nat Commun. 2019;10:4112 pubmed publisher
|
| Fujii W, Ito H, Kanke T, Ikeda A, Sugiura K, Naito K. Generation of genetically modified mice using SpCas9-NG engineered nuclease. Sci Rep. 2019;9:12878 pubmed publisher
|
| Burke J, Moon S, Matheny T, Parker R. RNase L Reprograms Translation by Widespread mRNA Turnover Escaped by Antiviral mRNAs. Mol Cell. 2019;75:1203-1217.e5 pubmed publisher
|
| Miao Q, Hill M, Chen F, Mo Q, Ku A, Ramos C, et al. SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair. Nat Commun. 2019;10:4042 pubmed publisher
|
| Bushell S, Pike A, Falzone M, Rorsman N, Ta C, Corey R, et al. The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K. Nat Commun. 2019;10:3956 pubmed publisher
|
| Sun Z, Xu X, He J, Murray A, Sun M, Wei X, et al. EGR1 recruits TET1 to shape the brain methylome during development and upon neuronal activity. Nat Commun. 2019;10:3892 pubmed publisher
|
| Hustedt N, Saito Y, Zimmermann M, Alvarez Quilón A, Setiaputra D, Adam S, et al. Control of homologous recombination by the HROB-MCM8-MCM9 pathway. Genes Dev. 2019;33:1397-1415 pubmed publisher
|
| Gómez H L, Felipe Medina N, Condezo Y, García Valiente R, Ramos I, Suja J, et al. The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility. PLoS Genet. 2019;15:e1008316 pubmed publisher
|
| Ordóñez A, Fernández B, Fdez E, Romo Lozano M, Madero Pérez J, Lobbestael E, et al. RAB8, RAB10 and RILPL1 contribute to both LRRK2 kinase-mediated centrosomal cohesion and ciliogenesis deficits. Hum Mol Genet. 2019;: pubmed publisher
|
| Kim Y, Lee S, Kim S, Jang H, Hwang I, Jin S, et al. Toll-like receptor mediated inflammation requires FASN-dependent MYD88 palmitoylation. Nat Chem Biol. 2019;15:907-916 pubmed publisher
|
| Kneuss E, Munafò M, Eastwood E, Deumer U, Preall J, Hannon G, et al. Specialization of the Drosophila nuclear export family protein Nxf3 for piRNA precursor export. Genes Dev. 2019;33:1208-1220 pubmed publisher
|
| Sharma N, Majerciak V, Kruhlak M, Yu L, Kang J, Yang A, et al. KSHV RNA-binding protein ORF57 inhibits P-body formation to promote viral multiplication by interaction with Ago2 and GW182. Nucleic Acids Res. 2019;47:9368-9385 pubmed publisher
|
| Annunziata I, van de Vlekkert D, Wolf E, Finkelstein D, Neale G, Machado E, et al. MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat. Nat Commun. 2019;10:3623 pubmed publisher
|
| Bohio A, Sattout A, Wang R, Wang K, Sah R, Guo X, et al. c-Abl-Mediated Tyrosine Phosphorylation of PARP1 Is Crucial for Expression of Proinflammatory Genes. J Immunol. 2019;203:1521-1531 pubmed publisher
|
| Eftekharzadeh B, Banduseela V, Chiesa G, Martínez Cristóbal P, Rauch J, Nath S, et al. Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor. Nat Commun. 2019;10:3562 pubmed publisher
|
| Schmidt N, Domingues P, Golebiowski F, Patzina C, Tatham M, Hay R, et al. An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity. Proc Natl Acad Sci U S A. 2019;116:17399-17408 pubmed publisher
|
| Uzquiano A, Cifuentes Diaz C, Jabali A, Romero D, Houllier A, Dingli F, et al. Mutations in the Heterotopia Gene Eml1/EML1 Severely Disrupt the Formation of Primary Cilia. Cell Rep. 2019;28:1596-1611.e10 pubmed publisher
|
| Yan H, Foo S, Chen W, Yoo J, Shin W, Wu C, et al. Efficient Inhibition of Human Papillomavirus Infection by L2 Minor Capsid-Derived Lipopeptide. MBio. 2019;10: pubmed publisher
|
| Lee C, Shin H, Kimble J. Dynamics of Notch-Dependent Transcriptional Bursting in Its Native Context. Dev Cell. 2019;50:426-435.e4 pubmed publisher
|
| Miyamoto Y, Nagayoshi I, Nishi A, Fukuda T. Three divisions of the mouse caudal striatum differ in the proportions of dopamine D1 and D2 receptor-expressing cells, distribution of dopaminergic axons, and composition of cholinergic and GABAergic interneurons. Brain Struct Funct. 2019;224:2703-2716 pubmed publisher
|
| Lee S, Park S, Lee H, Han S, Song J, Han D, et al. Nedd4 E3 ligase and beta-arrestins regulate ubiquitination, trafficking, and stability of the mGlu7 receptor. elife. 2019;8: pubmed publisher
|
| Brouwer M, Farzana F, Koopmans F, Chen N, Brunner J, Oldani S, et al. SALM1 controls synapse development by promoting F-actin/PIP2-dependent Neurexin clustering. EMBO J. 2019;38:e101289 pubmed publisher
|
| Kim D, An H, Shearer R, Sharif M, Fan C, Choi J, et al. A principled strategy for mapping enhancers to genes. Sci Rep. 2019;9:11043 pubmed publisher
|
| Nishino K, Watanabe S, Shijie J, Murata Y, Oiwa K, Komine O, et al. Mice deficient in the C-terminal domain of TAR DNA-binding protein 43 develop age-dependent motor dysfunction associated with impaired Notch1-Akt signaling pathway. Acta Neuropathol Commun. 2019;7:118 pubmed publisher
|
| Lan J, Rollins J, Zang X, Wu D, Zou L, Wang Z, et al. Translational Regulation of Non-autonomous Mitochondrial Stress Response Promotes Longevity. Cell Rep. 2019;28:1050-1062.e6 pubmed publisher
|
| Lobanovska M, Tang C, Exley R. Contribution of σ70 and σN Factors to Expression of Class II pilE in Neisseria meningitidis. J Bacteriol. 2019;201: pubmed publisher
|
| Singh A, Manjunath L, Kundu P, Sahoo S, Das A, Suma H, et al. Let-7a-regulated translational readthrough of mammalian AGO1 generates a microRNA pathway inhibitor. EMBO J. 2019;38:e100727 pubmed publisher
|
| Niemi N, Wilson G, Overmyer K, Vögtle F, Myketin L, Lohman D, et al. Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis. Nat Commun. 2019;10:3197 pubmed publisher
|
| Park M, Araya Secchi R, Brackbill J, Phan H, Kehling A, Abd El Wahab E, et al. Multidomain Convergence of Argonaute during RISC Assembly Correlates with the Formation of Internal Water Clusters. Mol Cell. 2019;75:725-740.e6 pubmed publisher
|
| Wang L, Long H, Zheng Q, Bo X, Xiao X, Li B. Circular RNA circRHOT1 promotes hepatocellular carcinoma progression by initiation of NR2F6 expression. Mol Cancer. 2019;18:119 pubmed publisher
|
| Peschek N, Hoyos M, Herzog R, Förstner K, Papenfort K. A conserved RNA seed-pairing domain directs small RNA-mediated stress resistance in enterobacteria. EMBO J. 2019;38:e101650 pubmed publisher
|
| Zhu C, Li L, Zhang Z, Bi M, Wang H, Su W, et al. A Non-canonical Role of YAP/TEAD Is Required for Activation of Estrogen-Regulated Enhancers in Breast Cancer. Mol Cell. 2019;75:791-806.e8 pubmed publisher
|
| Nishimura K, Dioguardi E, Nishio S, Villa A, Han L, Matsuda T, et al. Molecular basis of egg coat cross-linking sheds light on ZP1-associated female infertility. Nat Commun. 2019;10:3086 pubmed publisher
|
| Gillingham A, Bertram J, Begum F, Munro S. In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation. elife. 2019;8: pubmed publisher
|
| Leong S, Lynch E, Zou J, Tay Y, Borek W, Tuijtel M, et al. Reconstitution of Microtubule Nucleation In Vitro Reveals Novel Roles for Mzt1. Curr Biol. 2019;29:2199-2207.e10 pubmed publisher
|
| Sendinc E, Valle García D, Dhall A, Chen H, Henriques T, Navarrete Perea J, et al. PCIF1 Catalyzes m6Am mRNA Methylation to Regulate Gene Expression. Mol Cell. 2019;: pubmed publisher
|
| Boulias K, Toczydłowska Socha D, Hawley B, Liberman N, Takashima K, Zaccara S, et al. Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome. Mol Cell. 2019;: pubmed publisher
|
| Chen Z, Picaud S, Filippakopoulos P, D Angiolella V, Bullock A. Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase. Structure. 2019;: pubmed publisher
|
| Kikuma K, Li X, Perry S, Li Q, Goel P, Chen C, et al. Cul3 and insomniac are required for rapid ubiquitination of postsynaptic targets and retrograde homeostatic signaling. Nat Commun. 2019;10:2998 pubmed publisher
|
| Marivin A, Garcia Marcos M. DAPLE and MPDZ bind to each other and cooperate to promote apical cell constriction. Mol Biol Cell. 2019;:mbcE19020091 pubmed publisher
|
| Gao J, Chau S, Chowdhury F, Zhou T, Hossain S, McQuibban G, et al. Meiotic viral attenuation through an ancestral apoptotic pathway. Proc Natl Acad Sci U S A. 2019;116:16454-16462 pubmed publisher
|
| Gupta R, Walvekar A, Liang S, Rashida Z, Shah P, Laxman S. A tRNA modification balances carbon and nitrogen metabolism by regulating phosphate homeostasis. elife. 2019;8: pubmed publisher
|
| Moon I, Choi J, Chung J, Jang E, Jeong S, Kim J. MicroRNA‑20 induces methylation of hepatitis B virus covalently closed circular DNA in human hepatoma cells. Mol Med Rep. 2019;: pubmed publisher
|
| Jayavaradhan R, Pillis D, Goodman M, Zhang F, Zhang Y, Andreassen P, et al. CRISPR-Cas9 fusion to dominant-negative 53BP1 enhances HDR and inhibits NHEJ specifically at Cas9 target sites. Nat Commun. 2019;10:2866 pubmed publisher
|
| Ni Y, Schmidt K, Werner B, Koenig J, Guldner I, Schnepp P, et al. Death effector domain-containing protein induces vulnerability to cell cycle inhibition in triple-negative breast cancer. Nat Commun. 2019;10:2860 pubmed publisher
|
| Donayo A, Johnson R, Tseng H, Izreig S, Gariepy A, Mayya V, et al. Oncogenic Biogenesis of pri-miR-17∼92 Reveals Hierarchy and Competition among Polycistronic MicroRNAs. Mol Cell. 2019;: pubmed publisher
|
| Tian X, Zheng P, Zhou C, Wang X, Ma H, Ma W, et al. DIPK2A promotes STX17- and VAMP7-mediated autophagosome-lysosome fusion by binding to VAMP7B. Autophagy. 2019;:1-14 pubmed publisher
|
| De Santis R, Alfano V, de Turris V, Colantoni A, Santini L, Garone M, et al. Mutant FUS and ELAVL4 (HuD) Aberrant Crosstalk in Amyotrophic Lateral Sclerosis. Cell Rep. 2019;27:3818-3831.e5 pubmed publisher
|
| Shi C, Nabar N, Huang N, Kehrl J. SARS-Coronavirus Open Reading Frame-8b triggers intracellular stress pathways and activates NLRP3 inflammasomes. Cell Death Discov. 2019;5:101 pubmed publisher
|
| Mayank A, Pandey V, Vashisht A, Barshop W, Rayatpisheh S, Sharma T, et al. An Oxygen-Dependent Interaction between FBXL5 and the CIA-Targeting Complex Regulates Iron Homeostasis. Mol Cell. 2019;: pubmed publisher
|
| Xiao J, Lin H, Liu B, Jin J. CAMKII/Proteasome/Cytosolic calcium/Cathepsin B axis was present in Trypsin Activation induced by Nicardipine. Biosci Rep. 2019;: pubmed publisher
|
| Fabry M, Ciabrelli F, Munafò M, Eastwood E, Kneuss E, Falciatori I, et al. piRNA-guided co-transcriptional silencing coopts nuclear export factors. elife. 2019;8: pubmed publisher
|
| Minuesa G, Albanese S, Xie W, Kazansky Y, Worroll D, Chow A, et al. Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia. Nat Commun. 2019;10:2691 pubmed publisher
|
| Staller E, Sheppard C, Neasham P, Mistry B, Peacock T, Goldhill D, et al. ANP32 proteins are essential for influenza virus replication in human cells. J Virol. 2019;: pubmed publisher
|
| Burgener S, Leborgne N, Snipas S, Salvesen G, Bird P, Benarafa C. Cathepsin G Inhibition by Serpinb1 and Serpinb6 Prevents Programmed Necrosis in Neutrophils and Monocytes and Reduces GSDMD-Driven Inflammation. Cell Rep. 2019;27:3646-3656.e5 pubmed publisher
|
| Luo Z, Qing X, Benda C, Huang Z, Zhang M, Huang Y, et al. Nuclear-cytoplasmic shuttling of class IIa histone deacetylases regulates somatic cell reprogramming. Cell Regen (Lond). 2019;8:21-29 pubmed publisher
|
| Huang M, Tailor J, Zhen Q, Gillmor A, Miller M, Weishaupt H, et al. Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis. Cell Stem Cell. 2019;: pubmed publisher
|
| Courtney D, Chalem A, Bogerd H, Law B, Kennedy E, Holley C, et al. Extensive Epitranscriptomic Methylation of A and C Residues on Murine Leukemia Virus Transcripts Enhances Viral Gene Expression. MBio. 2019;10: pubmed publisher
|
| Ma C, Zhong P, Liu D, Barger Z, Zhou L, Chang W, et al. Sleep Regulation by Neurotensinergic Neurons in a Thalamo-Amygdala Circuit. Neuron. 2019;: pubmed publisher
|
| Hayward A, Aird E, Gordon W. A toolkit for studying cell surface shedding of diverse transmembrane receptors. elife. 2019;8: pubmed publisher
|
| Osório L, Wu X, Wang L, Jiang Z, Neideck C, Sheng G, et al. ISM1 regulates NODAL signaling and asymmetric organ morphogenesis during development. J Cell Biol. 2019;: pubmed publisher
|
| Yang Q, Bai S, Li L, Li S, Zhang Y, Munir M, et al. Human hemoglobin subunit beta functions as a pleiotropic regulator of the RIG-I/MDA5-mediated antiviral innate immune responses. J Virol. 2019;: pubmed publisher
|
| Ahn J, Cho M, Sohn S, Lee J. Inhibition of PP2A activity by H2O2 during mitosis disrupts nuclear envelope reassembly and alters nuclear shape. Exp Mol Med. 2019;51:64 pubmed publisher
|
| Sauer M, Juranek S, Marks J, De Magis A, Kazemier H, Hilbig D, et al. DHX36 prevents the accumulation of translationally inactive mRNAs with G4-structures in untranslated regions. Nat Commun. 2019;10:2421 pubmed publisher
|
| Long J, Idoko Akoh A, Mistry B, Goldhill D, Staller E, Schreyer J, et al. Species specific differences in use of ANP32 proteins by influenza A virus. elife. 2019;8: pubmed publisher
|
| Li J, Dong A, Saydaminova K, Chang H, Wang G, Ochiai H, et al. Single-Molecule Nanoscopy Elucidates RNA Polymerase II Transcription at Single Genes in Live Cells. Cell. 2019;: pubmed publisher
|
| Hammerschmidt P, Ostkotte D, Nolte H, Gerl M, Jais A, Brunner H, et al. CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity. Cell. 2019;177:1536-1552.e23 pubmed publisher
|
| Torres S, Gallagher C, Plate L, Gupta M, Liem C, Guo X, et al. Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether. elife. 2019;8: pubmed publisher
|
| Rong Z, Li Z, He J, Liu L, Ren X, Gao J, et al. Downregulation of Fat Mass and Obesity Associated (FTO) Promotes the Progression of Intrahepatic Cholangiocarcinoma. Front Oncol. 2019;9:369 pubmed publisher
|
| Luo Y, Barrios Rodiles M, Gupta G, Zhang Y, Ogunjimi A, Bashkurov M, et al. Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility. Nat Commun. 2019;10:2356 pubmed publisher
|
| Waters M, Gupta A, Mockenhaupt K, Brown L, Biswas D, Kordula T. RelB acts as a molecular switch driving chronic inflammation in glioblastoma multiforme. Oncogenesis. 2019;8:37 pubmed publisher
|
| Kozlova N, Mennerich D, Samoylenko A, Dimova E, Koivunen P, Biterova E, et al. The pro-oncogenic adaptor CIN85 acts as an inhibitory binding partner of hypoxia-inducible factor prolyl hydroxylase 2. Cancer Res. 2019;: pubmed publisher
|
| Han Y, Kwon J, Won J, An H, Jang M, Woo J, et al. Tweety-homolog (Ttyh) Family Encodes the Pore-forming Subunits of the Swelling-dependent Volume-regulated Anion Channel (VRACswell) in the Brain. Exp Neurobiol. 2019;28:183-215 pubmed publisher
|
| Figeac N, Mohamed A, Sun C, Schönfelder M, Matallanas D, Garcia Munoz A, et al. Vgll3 operates via Tead1, Tead3 and Tead4 to influence myogenesis in skeletal muscle. J Cell Sci. 2019;: pubmed publisher
|
| Das R, Schwintzer L, Vinopal S, Roca E, Sylvester M, Oprişoreanu A, et al. New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules. J Cell Sci. 2019;: pubmed publisher
|
| Marceau A, Brison C, Nerli S, Arsenault H, McShan A, Chen E, et al. An order-to-disorder structural switch activates the FoxM1 transcription factor. elife. 2019;8: pubmed publisher
|
| Park J, Lee S, Jeong H, Kang M, Van Haute L, Minczuk M, et al. The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. Nucleic Acids Res. 2019;47:7078-7093 pubmed publisher
|
| García Rodríguez F, Neira J, Marcia M, Molina Sánchez M, Toro N. A group II intron-encoded protein interacts with the cellular replicative machinery through the β-sliding clamp. Nucleic Acids Res. 2019;47:7605-7617 pubmed publisher
|
| van de Kooij B, Creixell P, van Vlimmeren A, Joughin B, Miller C, Haider N, et al. Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs. elife. 2019;8: pubmed publisher
|
| Munafò M, Manelli V, Falconio F, Sawle A, Kneuss E, Eastwood E, et al. Daedalus and Gasz recruit Armitage to mitochondria, bringing piRNA precursors to the biogenesis machinery. Genes Dev. 2019;33:844-856 pubmed publisher
|
| Gregersen L, Mitter R, Ugalde A, Nojima T, Proudfoot N, Agami R, et al. SCAF4 and SCAF8, mRNA Anti-Terminator Proteins. Cell. 2019;: pubmed publisher
|
| Jiang S, Athanasopoulos V, Ellyard J, Chuah A, Cappello J, Cook A, et al. Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus. Nat Commun. 2019;10:2201 pubmed publisher
|
| Hölzer K, Ori A, Cooke A, Dauch D, Drucker E, Riemenschneider P, et al. Nucleoporin Nup155 is part of the p53 network in liver cancer. Nat Commun. 2019;10:2147 pubmed publisher
|
| Pan C, Jin L, Wang X, Li Y, Chun J, Boese A, et al. Inositol-triphosphate 3-kinase B confers cisplatin resistance by regulating NOX4-dependent redox balance. J Clin Invest. 2019;129:2431-2445 pubmed publisher
|
| Saneyoshi T, Matsuno H, Suzuki A, Murakoshi H, Hedrick N, Agnello E, et al. Reciprocal Activation within a Kinase-Effector Complex Underlying Persistence of Structural LTP. Neuron. 2019;: pubmed publisher
|
| Liu M, Zhang L, Marsboom G, Jambusaria A, Xiong S, Toth P, et al. Sox17 is required for endothelial regeneration following inflammation-induced vascular injury. Nat Commun. 2019;10:2126 pubmed publisher
|
| Galvan D, Long J, Green N, CHANG B, Lin J, Schumacker P, et al. Drp1S600 phosphorylation regulates mitochondrial fission and progression of nephropathy in diabetic mice. J Clin Invest. 2019;130:2807-2823 pubmed publisher
|
| Mitchell D, Menon A, Garner A. Chemoproteomic Profiling Uncovers CDK4-Mediated Phosphorylation of the Translational Suppressor 4E-BP1. Cell Chem Biol. 2019;: pubmed publisher
|
| Ceccarelli D, Ivantsiv S, Mullin A, Coyaud E, Manczyk N, Maisonneuve P, et al. FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane. Structure. 2019;27:1000-1012.e6 pubmed publisher
|
| Carretero Ortega J, Chhangawala Z, Hunt S, Narvaez C, Menéndez González J, Gay C, et al. GIPC proteins negatively modulate Plexind1 signaling during vascular development. elife. 2019;8: pubmed publisher
|
| Lin Shiao E, Lan Y, Welzenbach J, Alexander K, Zhang Z, Knapp M, et al. p63 establishes epithelial enhancers at critical craniofacial development genes. Sci Adv. 2019;5:eaaw0946 pubmed publisher
|
| Huang X, Wei C, Li F, Jia L, Zeng P, Li J, et al. PCGF6 regulates stem cell pluripotency as a transcription activator via super-enhancer dependent chromatin interactions. Protein Cell. 2019;: pubmed publisher
|
| Rossi M, Bucci G, Rizzotto D, Bordo D, Marzi M, Puppo M, et al. LncRNA EPR controls epithelial proliferation by coordinating Cdkn1a transcription and mRNA decay response to TGF-β. Nat Commun. 2019;10:1969 pubmed publisher
|
| Moussa H, Bsteh D, Yelagandula R, Pribitzer C, Stecher K, Bartalska K, et al. Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing. Nat Commun. 2019;10:1931 pubmed publisher
|
| Pinto D, Scott T, DeMarino C, Pleet M, Vo T, Saifuddin M, et al. Effect of transcription inhibition and generation of suppressive viral non-coding RNAs. Retrovirology. 2019;16:13 pubmed publisher
|
| Xu D, Li X, Shao F, Lv G, Lv H, Lee J, et al. The protein kinase activity of fructokinase A specifies the antioxidant responses of tumor cells by phosphorylating p62. Sci Adv. 2019;5:eaav4570 pubmed publisher
|
| Kalkan T, Bornelöv S, Mulas C, Diamanti E, Lohoff T, Ralser M, et al. Complementary Activity of ETV5, RBPJ, and TCF3 Drives Formative Transition from Naive Pluripotency. Cell Stem Cell. 2019;24:785-801.e7 pubmed publisher
|
| Pandolfini L, Barbieri I, Bannister A, Hendrick A, Andrews B, Webster N, et al. METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation. Mol Cell. 2019;74:1278-1290.e9 pubmed publisher
|
| Texada M, Jørgensen A, Christensen C, Koyama T, Malita A, Smith D, et al. A fat-tissue sensor couples growth to oxygen availability by remotely controlling insulin secretion. Nat Commun. 2019;10:1955 pubmed publisher
|
| Yang Y, Liu Y, Huang L, Wang L, Liu K, Liu M, et al. Clinical Features and Cytokine Profile in Myositis Patients with Anti-EJ Autoantibodies Detected by a Novel Immunoprecipitation Assay. Biomed Res Int. 2019;2019:1856180 pubmed publisher
|
| Yan J, Shun M, Zhang Y, Hao C, Skowronski J. HIV-1 Vpr counteracts HLTF-mediated restriction of HIV-1 infection in T cells. Proc Natl Acad Sci U S A. 2019;116:9568-9577 pubmed publisher
|
| Lotta L, Mokrosinski J, Mendes de Oliveira E, Li C, Sharp S, Luan J, et al. Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity. Cell. 2019;177:597-607.e9 pubmed publisher
|
| Harnoš J, Canizal M, Jurásek M, Kumar J, Holler C, Schambony A, et al. Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1. Nat Commun. 2019;10:1804 pubmed publisher
|
| Zhang H, Zhang Z, Wang Y, Wang M, Wang X, Zhang X, et al. Fundamental Contribution and Host Range Determination of ANP32A and ANP32B in Influenza A Virus Polymerase Activity. J Virol. 2019;93: pubmed publisher
|
| Wei H, Lin L, Zhang X, Feng Z, Wang Y, You Y, et al. Effect of cytoglobin overexpression on extracellular matrix component synthesis in human tenon fibroblasts. Biol Res. 2019;52:23 pubmed publisher
|
| Topacio B, Zatulovskiy E, Cristea S, Xie S, Tambo C, Rubin S, et al. Cyclin D-Cdk4,6 Drives Cell-Cycle Progression via the Retinoblastoma Protein's C-Terminal Helix. Mol Cell. 2019;74:758-770.e4 pubmed publisher
|
| Shen K, Gamerdinger M, Chan R, Gense K, Martin E, Sachs N, et al. Dual Role of Ribosome-Binding Domain of NAC as a Potent Suppressor of Protein Aggregation and Aging-Related Proteinopathies. Mol Cell. 2019;74:729-741.e7 pubmed publisher
|
| Princely Abudu Y, Pankiv S, Mathai B, Håkon Lystad A, Bindesbøll C, Brenne H, et al. NIPSNAP1 and NIPSNAP2 Act as "Eat Me" Signals for Mitophagy. Dev Cell. 2019;49:509-525.e12 pubmed publisher
|
| Wang Y, Brady K, Caiello B, Ackerson S, Stewart J. Human CST suppresses origin licensing and promotes AND-1/Ctf4 chromatin association. Life Sci Alliance. 2019;2: pubmed publisher
|
| Pfister J, Ma C, D Mello S. Catalytic-independent neuroprotection by SIRT1 is mediated through interaction with HDAC1. PLoS ONE. 2019;14:e0215208 pubmed publisher
|
| Plegge T, Spiegel M, Krüger N, Nehlmeier I, Winkler M, González Hernández M, et al. Inhibitors of signal peptide peptidase and subtilisin/kexin-isozyme 1 inhibit Ebola virus glycoprotein-driven cell entry by interfering with activity and cellular localization of endosomal cathepsins. PLoS ONE. 2019;14:e0214968 pubmed publisher
|
| Ahler E, Register A, Chakraborty S, Fang L, Dieter E, Sitko K, et al. A Combined Approach Reveals a Regulatory Mechanism Coupling Src's Kinase Activity, Localization, and Phosphotransferase-Independent Functions. Mol Cell. 2019;74:393-408.e20 pubmed publisher
|
| Valverde D, Yu S, Boggavarapu V, Kumar N, Lees J, Walz T, et al. ATG2 transports lipids to promote autophagosome biogenesis. J Cell Biol. 2019;218:1787-1798 pubmed publisher
|
| Liu H, Huang T, Li M, Li M, Zhang C, Jiang J, et al. SCRE serves as a unique synaptonemal complex fastener and is essential for progression of meiosis prophase I in mice. Nucleic Acids Res. 2019;47:5670-5683 pubmed publisher
|
| Marivin A, Morozova V, Walawalkar I, Leyme A, Kretov D, Cifuentes D, et al. GPCR-independent activation of G proteins promotes apical cell constriction in vivo. J Cell Biol. 2019;218:1743-1763 pubmed publisher
|
| Herpin A, Schmidt C, Kneitz S, Gobé C, Regensburger M, Le Cam A, et al. A novel evolutionary conserved mechanism of RNA stability regulates synexpression of primordial germ cell-specific genes prior to the sex-determination stage in medaka. PLoS Biol. 2019;17:e3000185 pubmed publisher
|
| Dickinson M, Anderson L, Webb Robertson B, Hansen J, Smith R, Wright A, et al. Proximity-dependent proteomics of the Chlamydia trachomatis inclusion membrane reveals functional interactions with endoplasmic reticulum exit sites. PLoS Pathog. 2019;15:e1007698 pubmed publisher
|
| Bressin A, Schulte Sasse R, Figini D, Urdaneta E, Beckmann B, Marsico A. TriPepSVM: de novo prediction of RNA-binding proteins based on short amino acid motifs. Nucleic Acids Res. 2019;47:4406-4417 pubmed publisher
|
| Julian M, Rabia L, Desai A, Arsiwala A, Gerson J, Paulson H, et al. Nature-inspired design and evolution of anti-amyloid antibodies. J Biol Chem. 2019;294:8438-8451 pubmed publisher
|
| Zhang Q, Chao T, Patil V, Qin Y, Tiwari S, Chiou J, et al. The long noncoding RNA ROCKI regulates inflammatory gene expression. EMBO J. 2019;38: pubmed publisher
|
| Selberg S, Blokhina D, Aatonen M, Koivisto P, Siltanen A, Mervaala E, et al. Discovery of Small Molecules that Activate RNA Methylation through Cooperative Binding to the METTL3-14-WTAP Complex Active Site. Cell Rep. 2019;26:3762-3771.e5 pubmed publisher
|
| Tollenaere M, Tiedje C, Rasmussen S, Nielsen J, Vind A, Blasius M, et al. GIGYF1/2-Driven Cooperation between ZNF598 and TTP in Posttranscriptional Regulation of Inflammatory Signaling. Cell Rep. 2019;26:3511-3521.e4 pubmed publisher
|
| Chen T, Wang H, Liu J, Cheng H, Hsu S, Wu M, et al. Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation. Commun Biol. 2019;2:105 pubmed publisher
|
| Dinamarca M, Raveh A, Schneider A, Fritzius T, Früh S, Rem P, et al. Complex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing. Nat Commun. 2019;10:1331 pubmed publisher
|
| E X, Meraner P, Lu P, Perreira J, Aker A, McDougall W, et al. OR14I1 is a receptor for the human cytomegalovirus pentameric complex and defines viral epithelial cell tropism. Proc Natl Acad Sci U S A. 2019;116:7043-7052 pubmed publisher
|
| Gorla M, Santiago C, Chaudhari K, Layman A, Oliver P, Bashaw G. Ndfip Proteins Target Robo Receptors for Degradation and Allow Commissural Axons to Cross the Midline in the Developing Spinal Cord. Cell Rep. 2019;26:3298-3312.e4 pubmed publisher
|
| Wei X, Guo J, Li Q, Jia Q, Jing Q, Li Y, et al. Bach1 regulates self-renewal and impedes mesendodermal differentiation of human embryonic stem cells. Sci Adv. 2019;5:eaau7887 pubmed publisher
|
| Li T, Han J, Jia L, Hu X, Chen L, Wang Y. PKM2 coordinates glycolysis with mitochondrial fusion and oxidative phosphorylation. Protein Cell. 2019;: pubmed publisher
|
| Schwintzer L, Aguado Roca E, Broemer M. TRIAD3/RNF216 E3 ligase specifically synthesises K63-linked ubiquitin chains and is inactivated by mutations associated with Gordon Holmes syndrome. Cell Death Discov. 2019;5:75 pubmed publisher
|
| Qu Y, Deng C, Luo Q, Shang X, Wu J, Shi Y, et al. Arid1a regulates insulin sensitivity and lipid metabolism. EBioMedicine. 2019;42:481-493 pubmed publisher
|
| Pergu R, Dagar S, Kumar H, Kumar R, Bhattacharya J, Mylavarapu S. The chaperone ERp29 is required for tunneling nanotube formation by stabilizing MSec. J Biol Chem. 2019;294:7177-7193 pubmed publisher
|
| Arceci A, Bonacci T, Wang X, Stewart K, Damrauer J, Hoadley K, et al. FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer. Cell Rep. 2019;26:3076-3086.e6 pubmed publisher
|
| Ren J, Finney R, Ni K, Cam M, Muegge K. The chromatin remodeling protein Lsh alters nucleosome occupancy at putative enhancers and modulates binding of lineage specific transcription factors. Epigenetics. 2019;14:277-293 pubmed publisher
|
| Syafruddin S, Rodrigues P, Vojtasova E, Patel S, Zaini M, Burge J, et al. A KLF6-driven transcriptional network links lipid homeostasis and tumour growth in renal carcinoma. Nat Commun. 2019;10:1152 pubmed publisher
|
| Su L, Zhou L, Chen F, Wang H, Qian H, Sheng Y, et al. Cideb controls sterol-regulated ER export of SREBP/SCAP by promoting cargo loading at ER exit sites. EMBO J. 2019;38: pubmed publisher
|
| Kumar S, Gu Y, Abudu Y, Bruun J, Jain A, Farzam F, et al. Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation. Dev Cell. 2019;: pubmed publisher
|
| Wejaphikul K, Groeneweg S, Hilhorst Hofstee Y, Chatterjee V, Peeters R, Meima M, et al. Insight Into Molecular Determinants of T3 vs T4 Recognition From Mutations in Thyroid Hormone Receptor α and β. J Clin Endocrinol Metab. 2019;104:3491-3500 pubmed publisher
|
| Kojima M, de Rooij D, Page D. Amplification of a broad transcriptional program by a common factor triggers the meiotic cell cycle in mice. elife. 2019;8: pubmed publisher
|
| Cao J, Zhao M, Liu J, Zhang X, Pei Y, Wang J, et al. RACK1 Promotes Self-Renewal and Chemoresistance of Cancer Stem Cells in Human Hepatocellular Carcinoma through Stabilizing Nanog. Theranostics. 2019;9:811-828 pubmed publisher
|
| Shimojo M, Madara J, Pankow S, Liu X, Yates J, Sudhof T, et al. Synaptotagmin-11 mediates a vesicle trafficking pathway that is essential for development and synaptic plasticity. Genes Dev. 2019;33:365-376 pubmed publisher
|
| Denu R, Sass M, Johnson J, Potts G, Choudhary A, Coon J, et al. Polo-like kinase 4 maintains centriolar satellite integrity by phosphorylation of centrosomal protein 131 (CEP131). J Biol Chem. 2019;294:6531-6549 pubmed publisher
|
| Alfano L, Caporaso A, Altieri A, Dell Aquila M, Landi C, Bini L, et al. Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation. Nucleic Acids Res. 2019;47:4068-4085 pubmed publisher
|
| Escandell J, Carvalho E, Gallo Fernández M, Reis C, Matmati S, Luís I, et al. Ssu72 phosphatase is a conserved telomere replication terminator. EMBO J. 2019;38: pubmed publisher
|
| Matthews S, Eshelman M, Berg A, Koltun W, Yochum G. The Crohn's disease associated SNP rs6651252 impacts MYC gene expression in human colonic epithelial cells. PLoS ONE. 2019;14:e0212850 pubmed publisher
|
| Wang J, Chan B, Tong M, Paung Y, Jo U, MARTIN D, et al. Prolyl isomerization of FAAP20 catalyzed by PIN1 regulates the Fanconi anemia pathway. PLoS Genet. 2019;15:e1007983 pubmed publisher
|
| Lampi Y, Van Looveren D, Vranckx L, Thiry I, Bornschein S, Debyser Z, et al. Targeted editing of the PSIP1 gene encoding LEDGF/p75 protects cells against HIV infection. Sci Rep. 2019;9:2389 pubmed publisher
|
| Wang Z, Gong Y, Peng B, Shi R, Fan D, Zhao H, et al. MRE11 UFMylation promotes ATM activation. Nucleic Acids Res. 2019;47:4124-4135 pubmed publisher
|
| Mitsuhashi H, Homma S, Beermann M, Ishimaru S, Takeda H, Yu B, et al. Efficient system for upstream mRNA trans-splicing to generate covalent, head-to-tail, protein multimers. Sci Rep. 2019;9:2274 pubmed publisher
|
| Guo L, Cui C, Zhang K, Wang J, Wang Y, Lu Y, et al. Kindlin-2 links mechano-environment to proline synthesis and tumor growth. Nat Commun. 2019;10:845 pubmed publisher
|
| Wang X, Wang X, Zhang S, Sun H, Li S, Ding H, et al. The transcription factor TFCP2L1 induces expression of distinct target genes and promotes self-renewal of mouse and human embryonic stem cells. J Biol Chem. 2019;294:6007-6016 pubmed publisher
|
| Kunova Bosakova M, Nita A, Gregor T, Varecha M, Gudernová I, Fafilek B, et al. Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase. Proc Natl Acad Sci U S A. 2019;: pubmed publisher
|
| Monroe T, Hill M, Morikawa Y, Leach J, Heallen T, Cao S, et al. YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In Vivo. Dev Cell. 2019;48:765-779.e7 pubmed publisher
|
| Pearl J, Colantuoni C, Bergey D, Funk C, Shannon P, Basu B, et al. Genome-Scale Transcriptional Regulatory Network Models of Psychiatric and Neurodegenerative Disorders. Cell Syst. 2019;8:122-135.e7 pubmed publisher
|
| Bertran M, Mouilleron S, Zhou Y, Bajaj R, Uliana F, Kumar G, et al. ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail. Nat Commun. 2019;10:771 pubmed publisher
|
| Birgisdottir A, Mouilleron S, Bhujabal Z, Wirth M, Sjøttem E, Evjen G, et al. Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy. 2019;15:1333-1355 pubmed publisher
|
| Pascoe N, Seetharaman A, Teyra J, Manczyk N, Satori M, Tjandra D, et al. Yeast Two-Hybrid Analysis for Ubiquitin Variant Inhibitors of Human Deubiquitinases. J Mol Biol. 2019;: pubmed publisher
|
| Herb M, Gluschko A, Wiegmann K, Farid A, Wolf A, Utermöhlen O, et al. Mitochondrial reactive oxygen species enable proinflammatory signaling through disulfide linkage of NEMO. Sci Signal. 2019;12: pubmed publisher
|
| Oshima T, Niwa Y, Kuwata K, Srivastava A, Hyoda T, Tsuchiya Y, et al. Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth. Sci Adv. 2019;5:eaau9060 pubmed publisher
|
| Exner T, Romero Brey I, Yifrach E, Rivera Monroy J, Schrul B, Zouboulis C, et al. An alternative membrane topology permits lipid droplet localization of peroxisomal fatty acyl-CoA reductase 1. J Cell Sci. 2019;132: pubmed publisher
|
| Wang B, Xu X, Yang Z, Zhang L, Liu Y, Ma A, et al. POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1. EBioMedicine. 2019;41:320-332 pubmed publisher
|
| Ji C, Tang M, Zeidler C, Hohfeld J, Johnson G. BAG3 and SYNPO (synaptopodin) facilitate phospho-MAPT/Tau degradation via autophagy in neuronal processes. Autophagy. 2019;15:1199-1213 pubmed publisher
|
| Cho J, Xu Z, Parthasarathy U, Drashansky T, Helm E, Zuniga A, et al. Hectd3 promotes pathogenic Th17 lineage through Stat3 activation and Malt1 signaling in neuroinflammation. Nat Commun. 2019;10:701 pubmed publisher
|
| Araki K, Kawauchi K, Sugimoto W, Tsuda D, Oda H, Yoshida R, et al. Mitochondrial protein E2F3d, a distinctive E2F3 product, mediates hypoxia-induced mitophagy in cancer cells. Commun Biol. 2019;2:3 pubmed publisher
|
| Gallego Bartolome J, Liu W, Kuo P, Feng S, Ghoshal B, Gardiner J, et al. Co-targeting RNA Polymerases IV and V Promotes Efficient De Novo DNA Methylation in Arabidopsis. Cell. 2019;176:1068-1082.e19 pubmed publisher
|
| Bunda S, Heir P, Metcalf J, Li A, Agnihotri S, Pusch S, et al. CIC protein instability contributes to tumorigenesis in glioblastoma. Nat Commun. 2019;10:661 pubmed publisher
|
| Anderson R, Lagnado A, Maggiorani D, Walaszczyk A, Dookun E, Chapman J, et al. Length-independent telomere damage drives post-mitotic cardiomyocyte senescence. EMBO J. 2019;38: pubmed publisher
|
| Kopp F, Elguindy M, Yalvac M, Zhang H, Chen B, Gillett F, et al. PUMILIO hyperactivity drives premature aging of Norad-deficient mice. elife. 2019;8: pubmed publisher
|
| Sparrow A, Sievert K, Patel S, Chang Y, Broyles C, Brook F, et al. Measurement of Myofilament-Localized Calcium Dynamics in Adult Cardiomyocytes and the Effect of Hypertrophic Cardiomyopathy Mutations. Circ Res. 2019;124:1228-1239 pubmed publisher
|
| Shao J, Lu J, Zhu W, Yu H, Jing X, Wang Y, et al. Derepression of LOXL4 inhibits liver cancer growth by reactivating compromised p53. Cell Death Differ. 2019;: pubmed publisher
|
| Zhang T, Zhang Z, Shengzhao G, Li X, Liu H, Zhao Y. Strand break-induced replication fork collapse leads to C-circles, C-overhangs and telomeric recombination. PLoS Genet. 2019;15:e1007925 pubmed publisher
|
| Teyra J, Singer A, Schmitges F, Jaynes P, Kit Leng Lui S, Polyak M, et al. Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure. 2019;27:590-605.e5 pubmed publisher
|
| Rivero Ríos P, Romo Lozano M, Madero Pérez J, Thomas A, Biosa A, Greggio E, et al. The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A. J Biol Chem. 2019;294:4738-4758 pubmed publisher
|
| Marchand B, Pitarresi J, Reichert M, Suzuki K, Laczkó D, Rustgi A. PRRX1 isoforms cooperate with FOXM1 to regulate the DNA damage response in pancreatic cancer cells. Oncogene. 2019;38:4325-4339 pubmed publisher
|
| Sugihara M, Morito D, Ainuki S, Hirano Y, Ogino K, Kitamura A, et al. The AAA+ ATPase/ubiquitin ligase mysterin stabilizes cytoplasmic lipid droplets. J Cell Biol. 2019;218:949-960 pubmed publisher
|
| Magomedova L, Tiefenbach J, Zilberman E, Le Billan F, Voisin V, Saikali M, et al. ARGLU1 is a transcriptional coactivator and splicing regulator important for stress hormone signaling and development. Nucleic Acids Res. 2019;47:2856-2870 pubmed publisher
|
| Hwang W, Lan H, Cheng W, Huang S, Yang M. Tumor stem-like cell-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer. J Hematol Oncol. 2019;12:10 pubmed publisher
|
| Hwang J, Kim A, Kim K, Il Park J, Oh H, Moon S, et al. TAZ couples Hippo/Wnt signalling and insulin sensitivity through Irs1 expression. Nat Commun. 2019;10:421 pubmed publisher
|
| Martin J, Muccioli M, Herman K, Finnell R, Plageman T. Folic acid modifies the shape of epithelial cells during morphogenesis via a Folr1 and MLCK dependent mechanism. Biol Open. 2019;8: pubmed publisher
|
| Ho W, Tai Y, Chang J, Liang J, Tyan S, Chen S, et al. The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy. Autophagy. 2019;15:827-842 pubmed publisher
|
| Lohman D, Aydin D, Von Bank H, Smith R, Linke V, Weisenhorn E, et al. An Isoprene Lipid-Binding Protein Promotes Eukaryotic Coenzyme Q Biosynthesis. Mol Cell. 2019;73:763-774.e10 pubmed publisher
|
| Ericksen R, Lim S, McDonnell E, Shuen W, Vadiveloo M, White P, et al. Loss of BCAA Catabolism during Carcinogenesis Enhances mTORC1 Activity and Promotes Tumor Development and Progression. Cell Metab. 2019;: pubmed publisher
|
| Wheeler M, Jaronen M, Covacu R, Zandee S, Scalisi G, Rothhammer V, et al. Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation. Cell. 2019;176:581-596.e18 pubmed publisher
|
| Coyote Maestas W, He Y, Myers C, Schmidt D. Domain insertion permissibility-guided engineering of allostery in ion channels. Nat Commun. 2019;10:290 pubmed publisher
|
| Maurer A, Cepeda Diaz A, Vandenberghe L. Residues on Adeno-associated Virus Capsid Lumen Dictate Interactions and Compatibility with the Assembly-Activating Protein. J Virol. 2019;93: pubmed publisher
|
| Wang D, Xu Q, Yuan Q, Jia M, Niu H, Liu X, et al. Proteasome inhibition boosts autophagic degradation of ubiquitinated-AGR2 and enhances the antitumor efficiency of bevacizumab. Oncogene. 2019;38:3458-3474 pubmed publisher
|
| Kano Y, Gebregiworgis T, Marshall C, Radulovich N, Poon B, St Germain J, et al. Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation. Nat Commun. 2019;10:224 pubmed publisher
|
| Kovalski J, Bhaduri A, Zehnder A, Neela P, Che Y, Wozniak G, et al. The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2. Mol Cell. 2019;73:830-844.e12 pubmed publisher
|
| Henriksson J, Chen X, Gomes T, Ullah U, Meyer K, Miragaia R, et al. Genome-wide CRISPR Screens in T Helper Cells Reveal Pervasive Crosstalk between Activation and Differentiation. Cell. 2019;176:882-896.e18 pubmed publisher
|
| Smith B, Wang S, Jaime Figueroa S, Harbin A, Wang J, Hamman B, et al. Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase. Nat Commun. 2019;10:131 pubmed publisher
|
| Kusakabe S, Suzuki T, Sugiyama Y, Haga S, Horike K, Tokunaga M, et al. USP15 Participates in Hepatitis C Virus Propagation through Regulation of Viral RNA Translation and Lipid Droplet Formation. J Virol. 2019;93: pubmed publisher
|
| Yao Y, Yang B, Chen Y, Wang H, Hu X, Zhou Y, et al. RNA-Binding Motif Protein 24 (RBM24) Is Involved in Pregenomic RNA Packaging by Mediating Interaction between Hepatitis B Virus Polymerase and the Epsilon Element. J Virol. 2019;93: pubmed publisher
|
| Murakawa T, Okamoto K, Omiya S, Taneike M, Yamaguchi O, Otsu K. A Mammalian Mitophagy Receptor, Bcl2-L-13, Recruits the ULK1 Complex to Induce Mitophagy. Cell Rep. 2019;26:338-345.e6 pubmed publisher
|
| Mehto S, Jena K, Nath P, Chauhan S, Kolapalli S, Das S, et al. The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy. Mol Cell. 2019;73:429-445.e7 pubmed publisher
|
| Wang J, Hao J, Wang X, Guo H, Sun H, Lai X, et al. DHHC4 and DHHC5 Facilitate Fatty Acid Uptake by Palmitoylating and Targeting CD36 to the Plasma Membrane. Cell Rep. 2019;26:209-221.e5 pubmed publisher
|
| Moens T, Niccoli T, Wilson K, Atilano M, Birsa N, Gittings L, et al. C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A. Acta Neuropathol. 2019;137:487-500 pubmed publisher
|
| Yang X, Hu Z, Zhang Q, Fan S, Zhong Y, Guo D, et al. SG formation relies on eIF4GI-G3BP interaction which is targeted by picornavirus stress antagonists. Cell Discov. 2019;5:1 pubmed publisher
|
| Larson J, Kasper L, Paugh B, Jin H, Wu G, Kwon C, et al. Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression. Cancer Cell. 2019;35:140-155.e7 pubmed publisher
|
| Villegas F, Lehalle D, Mayer D, Rittirsch M, Stadler M, Zinner M, et al. Lysosomal Signaling Licenses Embryonic Stem Cell Differentiation via Inactivation of Tfe3. Cell Stem Cell. 2019;24:257-270.e8 pubmed publisher
|
| Żylicz J, Bousard A, Zumer K, Dossin F, Mohammad E, da Rocha S, et al. The Implication of Early Chromatin Changes in X Chromosome Inactivation. Cell. 2019;176:182-197.e23 pubmed publisher
|
| Ding D, Liu J, Dong K, Melnick A, Latham K, Chen C. Mitochondrial membrane-based initial separation of MIWI and MILI functions during pachytene piRNA biogenesis. Nucleic Acids Res. 2019;47:2594-2608 pubmed publisher
|
| Chen C, Wang H, Huang C, Huang C, Lim W, Tu I, et al. Two separate functions of NME3 critical for cell survival underlie a neurodegenerative disorder. Proc Natl Acad Sci U S A. 2019;116:566-574 pubmed publisher
|
| Lyu Q, Xu S, Lyu Y, Choi M, Christie C, Slivano O, et al. SENCR stabilizes vascular endothelial cell adherens junctions through interaction with CKAP4. Proc Natl Acad Sci U S A. 2019;116:546-555 pubmed publisher
|
| Locke M, Thorner J. Rab5 GTPases are required for optimal TORC2 function. J Cell Biol. 2019;218:961-976 pubmed publisher
|
| Saeed U, Kim J, Piracha Z, Kwon H, Jung J, Chwae Y, et al. Parvulin 14 and Parvulin 17 Bind to HBx and cccDNA and Upregulate Hepatitis B Virus Replication from cccDNA to Virion in an HBx-Dependent Manner. J Virol. 2019;93: pubmed publisher
|
| Li Q, Chen D, Xiang Q, Nicholas J. Insulin-Like Growth Factor 2 Receptor Expression Is Promoted by Human Herpesvirus 8-Encoded Interleukin-6 and Contributes to Viral Latency and Productive Replication. J Virol. 2019;93: pubmed publisher
|
| Papp B, Motlagh N, Smindak R, Jin Jang S, Sharma A, Alonso J, et al. Genome-Wide Identification of Direct RTA Targets Reveals Key Host Factors for Kaposi's Sarcoma-Associated Herpesvirus Lytic Reactivation. J Virol. 2019;93: pubmed publisher
|
| Miyakoshi M, Matera G, Maki K, Sone Y, Vogel J. Functional expansion of a TCA cycle operon mRNA by a 3' end-derived small RNA. Nucleic Acids Res. 2019;47:2075-2088 pubmed publisher
|
| Hatzi K, Geng H, Doane A, Meydan C, LaRiviere R, Cárdenas M, et al. Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis. Nat Immunol. 2019;20:86-96 pubmed publisher
|
| Vandemoortele G, De Sutter D, Moliere A, Pauwels J, Gevaert K, Eyckerman S. A Well-Controlled BioID Design for Endogenous Bait Proteins. J Proteome Res. 2019;18:95-106 pubmed publisher
|
| Gujrati M, Mittal R, Ekal L, Mishra R. SUMOylation of periplakin is critical for efficient reorganization of keratin filament network. Mol Biol Cell. 2019;30:357-369 pubmed publisher
|
| Park H, He A, Tan M, Johnson J, Dean J, Pietka T, et al. Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission. J Clin Invest. 2019;129:694-711 pubmed publisher
|
| Kobayashi S, Fukatsu R, Kanoh Y, Kakusho N, Matsumoto S, Chaen S, et al. Both a Unique Motif at the C Terminus and an N-Terminal HEAT Repeat Contribute to G-Quadruplex Binding and Origin Regulation by the Rif1 Protein. Mol Cell Biol. 2019;39: pubmed publisher
|
| Mirza A, McKellar S, Urman N, Brown A, Hollmig T, Aasi S, et al. LAP2 Proteins Chaperone GLI1 Movement between the Lamina and Chromatin to Regulate Transcription. Cell. 2019;176:198-212.e15 pubmed publisher
|
| Wu H, Shi L, Zhang Y, Peng X, Zheng T, Li Y, et al. Ubiquitination Is Essential for Avibirnavirus Replication by Supporting VP1 Polymerase Activity. J Virol. 2019;93: pubmed publisher
|
| Mun K, Punga T. Cellular Zinc Finger Protein 622 Hinders Human Adenovirus Lytic Growth and Limits Binding of the Viral pVII Protein to Virus DNA. J Virol. 2019;93: pubmed publisher
|
| Nguyen K, Lee C, Mun S, Truong N, Park S, Hwang C. N-terminal acetylation and the N-end rule pathway control degradation of the lipid droplet protein PLIN2. J Biol Chem. 2019;294:379-388 pubmed publisher
|
| CHENG A, Yockteng Melgar J, Jarvis M, Malik Soni N, Borozan I, Carpenter M, et al. Epstein-Barr virus BORF2 inhibits cellular APOBEC3B to preserve viral genome integrity. Nat Microbiol. 2019;4:78-88 pubmed publisher
|
| Zhang J, Tan P, Guo L, Gong J, Ma J, Li J, et al. p53-dependent autophagic degradation of TET2 modulates cancer therapeutic resistance. Oncogene. 2019;38:1905-1919 pubmed publisher
|
| Frazier N, Brand T, Gordan J, Grandis J, Jura N. Overexpression-mediated activation of MET in the Golgi promotes HER3/ERBB3 phosphorylation. Oncogene. 2019;38:1936-1950 pubmed publisher
|
| Hao H, Hao S, Chen H, Chen Z, Zhang Y, Wang J, et al. N6-methyladenosine modification and METTL3 modulate enterovirus 71 replication. Nucleic Acids Res. 2019;47:362-374 pubmed publisher
|
| Tomita T, Hirayama S, Sakurai Y, Ohte Y, Yoshihara H, Saeki Y, et al. Specific Modification of Aged Proteasomes Revealed by Tag-Exchangeable Knock-In Mice. Mol Cell Biol. 2019;39: pubmed publisher
|
| Tellier M, Chalmers R. Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome. Nucleic Acids Res. 2019;47:122-133 pubmed publisher
|
| Zhang H, Wang Y, Dou J, Guo Y, He J, Li L, et al. Acetylation of AGO2 promotes cancer progression by increasing oncogenic miR-19b biogenesis. Oncogene. 2019;38:1410-1431 pubmed publisher
|
| Feng J, Zhang Y, She X, Sun Y, Fan L, Ren X, et al. Hypermethylated gene ANKDD1A is a candidate tumor suppressor that interacts with FIH1 and decreases HIF1α stability to inhibit cell autophagy in the glioblastoma multiforme hypoxia microenvironment. Oncogene. 2019;38:103-119 pubmed publisher
|
| Wang Y, Sun H, Kumar S, Puerta M, Jo H, Rezvan A. ZBTB46 is a shear-sensitive transcription factor inhibiting endothelial cell proliferation via gene expression regulation of cell cycle proteins. Lab Invest. 2019;99:305-318 pubmed publisher
|
| Yang Q, Tang J, Pei R, Gao X, Guo J, Xu C, et al. Host HDAC4 regulates the antiviral response by inhibiting the phosphorylation of IRF3. J Mol Cell Biol. 2019;11:158-169 pubmed publisher
|
| Shao W, Li S, Li L, Lin K, Liu X, Wang H, et al. Chemical genomics reveals inhibition of breast cancer lung metastasis by Ponatinib via c-Jun. Protein Cell. 2019;10:161-177 pubmed publisher
|
| Ræder S, Nepal A, Bjørås K, Seelinger M, Kolve R, Nedal A, et al. APIM-Mediated REV3L⁻PCNA Interaction Important for Error Free TLS Over UV-Induced DNA Lesions in Human Cells. Int J Mol Sci. 2018;20: pubmed publisher
|
| Turer E, San Miguel M, Wang K, McAlpine W, Ou F, Li X, et al. A viable hypomorphic Arnt2 mutation causes hyperphagic obesity, diabetes and hepatic steatosis. Dis Model Mech. 2018;11: pubmed publisher
|
| Chen K, Yu C, Kung S, Chen S, Chang C, Ho T, et al. Toll-Like Receptor 3 Is Involved in Detection of Enterovirus A71 Infection and Targeted by Viral 2A Protease. Viruses. 2018;10: pubmed publisher
|
| Riddell M, Nakayama A, Hikita T, Mirzapourshafiyi F, Kawamura T, Pasha A, et al. aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability. Nat Commun. 2018;9:5357 pubmed publisher
|
| Batra J, Hultquist J, Liu D, Shtanko O, Von Dollen J, Satkamp L, et al. Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication. Cell. 2018;175:1917-1930.e13 pubmed publisher
|
| Kallimasioti Pazi E, Thelakkad Chathoth K, Taylor G, Meynert A, Ballinger T, Kelder M, et al. Heterochromatin delays CRISPR-Cas9 mutagenesis but does not influence the outcome of mutagenic DNA repair. PLoS Biol. 2018;16:e2005595 pubmed publisher
|
| Bowie E, Norris R, Anderson K, Goetz S. Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability. PLoS Genet. 2018;14:e1007844 pubmed publisher
|
| Zhang Q, Tran T, Wang M, Ranek M, Kokkonen Simon K, Gao J, et al. Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis. Nat Commun. 2018;9:5230 pubmed publisher
|
| Gao Z, Herrera Carrillo E, Berkhout B. A Single H1 Promoter Can Drive Both Guide RNA and Endonuclease Expression in the CRISPR-Cas9 System. Mol Ther Nucleic Acids. 2018;14:32-40 pubmed publisher
|
| Yamaguchi H, Hopf F, Li S, de Lecea L. In vivo cell type-specific CRISPR knockdown of dopamine beta hydroxylase reduces locus coeruleus evoked wakefulness. Nat Commun. 2018;9:5211 pubmed publisher
|
| Durré T, Morfoisse F, Erpicum C, Ebroin M, Blacher S, García Caballero M, et al. uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis. Nat Commun. 2018;9:5178 pubmed publisher
|
| Bainor A, Saini S, Calderon A, Casado Polanco R, Giner Ramirez B, Moncada C, et al. The HDAC-Associated Sin3B Protein Represses DREAM Complex Targets and Cooperates with APC/C to Promote Quiescence. Cell Rep. 2018;25:2797-2807.e8 pubmed publisher
|
| Zhang K, Zhang Y, Gu L, Lan M, Liu C, Wang M, et al. Islr regulates canonical Wnt signaling-mediated skeletal muscle regeneration by stabilizing Dishevelled-2 and preventing autophagy. Nat Commun. 2018;9:5129 pubmed publisher
|
| Pyun J, Kim H, Jeong M, Ahn B, Vuong T, Lee D, et al. Cardiac specific PRMT1 ablation causes heart failure through CaMKII dysregulation. Nat Commun. 2018;9:5107 pubmed publisher
|
| Nagai N, Ohguchi H, Nakaki R, Matsumura Y, Kanki Y, Sakai J, et al. Downregulation of ERG and FLI1 expression in endothelial cells triggers endothelial-to-mesenchymal transition. PLoS Genet. 2018;14:e1007826 pubmed publisher
|
| Wang H, Li S, Zhang H, Wang Y, Hao S, Wu X. BLM prevents instability of structure-forming DNA sequences at common fragile sites. PLoS Genet. 2018;14:e1007816 pubmed publisher
|
| Cijsouw T, Ramsey A, Lam T, Carbone B, Blanpied T, Biederer T. Mapping the Proteome of the Synaptic Cleft through Proximity Labeling Reveals New Cleft Proteins. Proteomes. 2018;6: pubmed publisher
|
| Ruiz Estévez M, Staats J, Paatela E, Munson D, Katoku Kikyo N, Yuan C, et al. Promotion of Myoblast Differentiation by Fkbp5 via Cdk4 Isomerization. Cell Rep. 2018;25:2537-2551.e8 pubmed publisher
|
| Lee S, Cieply B, Yang Y, Peart N, Glaser C, Chan P, et al. Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity. Cell Rep. 2018;25:2417-2430.e5 pubmed publisher
|
| Shi M, Chen B, Mahajan D, Boh B, Zhou Y, Dutta B, et al. Amino acids stimulate the endosome-to-Golgi trafficking through Ragulator and small GTPase Arl5. Nat Commun. 2018;9:4987 pubmed publisher
|
| Qu Z, Titus A, Xuan Z, D Mello S. Neuroprotection by Heat Shock Factor-1 (HSF1) and Trimerization-Deficient Mutant Identifies Novel Alterations in Gene Expression. Sci Rep. 2018;8:17255 pubmed publisher
|
| Lee S, Lee W, Kim N, Kang J, Kim K, Kim S, et al. Renal Cell Carcinoma Is Abrogated by p53 Stabilization through Transglutaminase 2 Inhibition. Cancers (Basel). 2018;10: pubmed publisher
|
| El Daher M, Cagnard N, Gil M, Da Cruz M, Leveau C, Sepulveda F, et al. Tetratricopeptide repeat domain 7A is a nuclear factor that modulates transcription and chromatin structure. Cell Discov. 2018;4:61 pubmed publisher
|
| Zhang H, Pandey S, Travers M, Sun H, Morton G, Madzo J, et al. Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer. Cell. 2018;175:1244-1258.e26 pubmed publisher
|
| Kory N, Wyant G, Prakash G, Uit de Bos J, Bottanelli F, Pacold M, et al. SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism. Science. 2018;362: pubmed publisher
|
| Somerville T, Xu Y, Miyabayashi K, Tiriac H, Cleary C, Maia Silva D, et al. TP63-Mediated Enhancer Reprogramming Drives the Squamous Subtype of Pancreatic Ductal Adenocarcinoma. Cell Rep. 2018;25:1741-1755.e7 pubmed publisher
|
| Oh J, Lee S, Rothstein R, Symington L. Xrs2 and Tel1 Independently Contribute to MR-Mediated DNA Tethering and Replisome Stability. Cell Rep. 2018;25:1681-1692.e4 pubmed publisher
|
| Pereira C, Reis R, Gama J, Celestino R, Cheerambathur D, Carvalho A, et al. Self-Assembly of the RZZ Complex into Filaments Drives Kinetochore Expansion in the Absence of Microtubule Attachment. Curr Biol. 2018;28:3408-3421.e8 pubmed publisher
|
| Cui C, Zhang Y, Wang C, Yuan F, Li H, Yao Y, et al. Dynamic ubiquitylation of Sox2 regulates proteostasis and governs neural progenitor cell differentiation. Nat Commun. 2018;9:4648 pubmed publisher
|
| Elbediwy A, Vanyai H, Díaz de la Loza M, Frith D, Snijders A, Thompson B. Enigma proteins regulate YAP mechanotransduction. J Cell Sci. 2018;131: pubmed publisher
|
| Moll L, Roitenberg N, Bejerano Sagie M, Boocholez H, Carvalhal Marques F, Volovik Y, et al. The insulin/IGF signaling cascade modulates SUMOylation to regulate aging and proteostasis in Caenorhabditis elegans. elife. 2018;7: pubmed publisher
|
| Chang L, Azzolin L, Di Biagio D, Zanconato F, Battilana G, Lucon Xiccato R, et al. The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ. Nature. 2018;563:265-269 pubmed publisher
|
| Lynch J, Dolman A, Guo C, Dolan K, Xiang C, Reda S, et al. Mutant myocilin impacts sarcomere ultrastructure in mouse gastrocnemius muscle. PLoS ONE. 2018;13:e0206801 pubmed publisher
|
| Deng Y, Pakdel M, Blank B, Sundberg E, Burd C, von Blume J. Activity of the SPCA1 Calcium Pump Couples Sphingomyelin Synthesis to Sorting of Secretory Proteins in the Trans-Golgi Network. Dev Cell. 2018;47:464-478.e8 pubmed publisher
|
| Hara H, Seregin S, Yang D, Fukase K, Chamaillard M, Alnemri E, et al. The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection. Cell. 2018;175:1651-1664.e14 pubmed publisher
|
| Shacham Silverberg V, Sar Shalom H, Goldner R, Golan Vaishenker Y, Gurwicz N, Gokhman I, et al. Phosphatidylserine is a marker for axonal debris engulfment but its exposure can be decoupled from degeneration. Cell Death Dis. 2018;9:1116 pubmed publisher
|
| Blázquez L, Emmett W, Faraway R, Pineda J, Bajew S, Gohr A, et al. Exon Junction Complex Shapes the Transcriptome by Repressing Recursive Splicing. Mol Cell. 2018;72:496-509.e9 pubmed publisher
|
| Georges A, Marcon E, Greenblatt J, Frappier L. Identification and Characterization of USP7 Targets in Cancer Cells. Sci Rep. 2018;8:15833 pubmed publisher
|
| Hamoud N, Tran V, Aimi T, Kakegawa W, Lahaie S, Thibault M, et al. Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion. Nat Commun. 2018;9:4470 pubmed publisher
|
| Tian H, Billings T, Petkov P. CXXC1 is not essential for normal DNA double-strand break formation and meiotic recombination in mouse. PLoS Genet. 2018;14:e1007657 pubmed publisher
|
| Ke C, Lin Y, Wang Y, Wu Y, Chen M, Ku W, et al. TBC1D21 Potentially Interacts with and Regulates Rap1 during Murine Spermatogenesis. Int J Mol Sci. 2018;19: pubmed publisher
|
| Bayo J, Tran T, Wang L, Peña Llopis S, Das A, Martinez E. Jumonji Inhibitors Overcome Radioresistance in Cancer through Changes in H3K4 Methylation at Double-Strand Breaks. Cell Rep. 2018;25:1040-1050.e5 pubmed publisher
|
| Ivanyi Nagy R, Ahmed S, Peter S, Ramani P, Ong P, Dreesen O, et al. The RNA interactome of human telomerase RNA reveals a coding-independent role for a histone mRNA in telomere homeostasis. elife. 2018;7: pubmed publisher
|
| Bruschetta G, Kim J, Diano S, Chan L. Overexpression of melanocortin 2 receptor accessory protein 2 (MRAP2) in adult paraventricular MC4R neurons regulates energy intake and expenditure. Mol Metab. 2018;18:79-87 pubmed publisher
|
| Nakaya T, Maragkakis M. Amyotrophic Lateral Sclerosis associated FUS mutation shortens mitochondria and induces neurotoxicity. Sci Rep. 2018;8:15575 pubmed publisher
|
| Harris N, Fetter R, Brasier D, Tong A, Davis G. Molecular Interface of Neuronal Innate Immunity, Synaptic Vesicle Stabilization, and Presynaptic Homeostatic Plasticity. Neuron. 2018;: pubmed publisher
|
| Ventura S, Cano F, Kannan Y, Breyer F, Pattison M, Wilson M, et al. A20-binding inhibitor of NF-κB (ABIN) 2 negatively regulates allergic airway inflammation. J Exp Med. 2018;215:2737-2747 pubmed publisher
|
| Masuda Y, Mitsuyuki S, Kanao R, Hishiki A, Hashimoto H, Masutani C. Regulation of HLTF-mediated PCNA polyubiquitination by RFC and PCNA monoubiquitination levels determines choice of damage tolerance pathway. Nucleic Acids Res. 2018;46:11340-11356 pubmed publisher
|
| Hrit J, Goodrich L, Li C, Wang B, Nie J, Cui X, et al. OGT binds a conserved C-terminal domain of TET1 to regulate TET1 activity and function in development. elife. 2018;7: pubmed publisher
|
| Bollong M, Lee G, Coukos J, Yun H, Zambaldo C, Chang J, et al. A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signalling. Nature. 2018;562:600-604 pubmed publisher
|
| Li B, Yu L, Liu D, Yang X, Zheng Y, Gui Y, et al. MIB1 mutations reduce Notch signaling activation and contribute to congenital heart disease. Clin Sci (Lond). 2018;132:2483-2491 pubmed publisher
|
| Bayrer J, Wang H, Nattiv R, Suzawa M, Escusa H, Fletterick R, et al. LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival. Nat Commun. 2018;9:4055 pubmed publisher
|
| Poulard C, Baulu E, Lee B, Pufall M, Stallcup M. Increasing G9a automethylation sensitizes B acute lymphoblastic leukemia cells to glucocorticoid-induced death. Cell Death Dis. 2018;9:1038 pubmed publisher
|
| Li Y, Maine E. The balance of poly(U) polymerase activity ensures germline identity, survival and development in Caenorhabditis elegans. Development. 2018;145: pubmed publisher
|
| Zheng S, Li D, Lu Z, Liu G, Wang M, Xing P, et al. Bre1-dependent H2B ubiquitination promotes homologous recombination by stimulating histone eviction at DNA breaks. Nucleic Acids Res. 2018;46:11326-11339 pubmed publisher
|
| Villiger L, Grisch Chan H, Lindsay H, Ringnalda F, Pogliano C, Allegri G, et al. Treatment of a metabolic liver disease by in vivo genome base editing in adult mice. Nat Med. 2018;24:1519-1525 pubmed publisher
|
| Yurkovetskiy L, Guney M, Kim K, Goh S, McCauley S, Dauphin A, et al. Primate immunodeficiency virus proteins Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex. Nat Microbiol. 2018;3:1354-1361 pubmed publisher
|
| Wu S, Fatkhutdinov N, Fukumoto T, Bitler B, Park P, Kossenkov A, et al. SWI/SNF catalytic subunits' switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells. Nat Commun. 2018;9:4116 pubmed publisher
|
| Leonardi M, Perna E, Tronnolone S, Colecchia D, Chiariello M. Activated kinase screening identifies the IKBKE oncogene as a positive regulator of autophagy. Autophagy. 2018;:1-15 pubmed publisher
|
| Zhang H, Fredericks T, Xiong G, Qi Y, Rychahou P, Li J, et al. Membrane associated collagen XIII promotes cancer metastasis and enhances anoikis resistance. Breast Cancer Res. 2018;20:116 pubmed publisher
|
| Song J, Liu Y, Gao P, Hu Y, Chai Y, Zhou S, et al. Mapping the Nonstructural Protein Interaction Network of Porcine Reproductive and Respiratory Syndrome Virus. J Virol. 2018;92: pubmed publisher
|
| Li Q, Li Y, Yang S, Huang S, Yan M, Ding Y, et al. CRISPR-Cas9-mediated base-editing screening in mice identifies DND1 amino acids that are critical for primordial germ cell development. Nat Cell Biol. 2018;20:1315-1325 pubmed publisher
|
| Munoz I, Morgan M, Peltier J, Weiland F, Gregorczyk M, Brown F, et al. Phosphoproteomic screening identifies physiological substrates of the CDKL5 kinase. EMBO J. 2018;37: pubmed publisher
|
| Whitlock J, Yu K, Cui Y, Hartzell H. Anoctamin 5/TMEM16E facilitates muscle precursor cell fusion. J Gen Physiol. 2018;150:1498-1509 pubmed publisher
|
| Lee D, Takayama S, Goldberg A. ZFAND5/ZNF216 is an activator of the 26S proteasome that stimulates overall protein degradation. Proc Natl Acad Sci U S A. 2018;115:E9550-E9559 pubmed publisher
|
| Gammage P, Viscomi C, Simard M, Costa A, Gaude E, Powell C, et al. Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo. Nat Med. 2018;24:1691-1695 pubmed publisher
|
| Fort L, Batista J, Thomason P, Spence H, Whitelaw J, Tweedy L, et al. Fam49/CYRI interacts with Rac1 and locally suppresses protrusions. Nat Cell Biol. 2018;20:1159-1171 pubmed publisher
|
| Huang H, Teng P, Du J, Meng J, Hu X, Tang T, et al. Interactive Repression of MYRF Self-Cleavage and Activity in Oligodendrocyte Differentiation by TMEM98 Protein. J Neurosci. 2018;38:9829-9839 pubmed publisher
|
| Wang M, Yang W, Chen Y, Wang J, Tan J, Qiao W. Cellular RelB interacts with the transactivator Tat and enhance HIV-1 expression. Retrovirology. 2018;15:65 pubmed publisher
|
| Jin H, Choi S, Kang M, Yun S, Kwon D, Noh Y, et al. Salicylic acid-induced transcriptional reprogramming by the HAC-NPR1-TGA histone acetyltransferase complex in Arabidopsis. Nucleic Acids Res. 2018;46:11712-11725 pubmed publisher
|
| Paakkola T, Salokas K, Miinalainen I, Lehtonen S, Manninen A, Kaakinen M, et al. Biallelic mutations in human NHLRC2 enhance myofibroblast differentiation in FINCA disease. Hum Mol Genet. 2018;27:4288-4302 pubmed publisher
|
| Hinchy E, Gruszczyk A, Willows R, Navaratnam N, Hall A, Bates G, et al. Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly. J Biol Chem. 2018;293:17208-17217 pubmed publisher
|
| de la Fuente S, Lambert J, Nichtova Z, Fernandez Sanz C, Elrod J, Sheu S, et al. Spatial Separation of Mitochondrial Calcium Uptake and Extrusion for Energy-Efficient Mitochondrial Calcium Signaling in the Heart. Cell Rep. 2018;24:3099-3107.e4 pubmed publisher
|
| Cheng X, Jobin Robitaille O, Billon P, Buisson R, Niu H, Lacoste N, et al. Phospho-dependent recruitment of the yeast NuA4 acetyltransferase complex by MRX at DNA breaks regulates RPA dynamics during resection. Proc Natl Acad Sci U S A. 2018;115:10028-10033 pubmed publisher
|
| McBrayer S, Mayers J, DiNatale G, Shi D, Khanal J, Chakraborty A, et al. Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma. Cell. 2018;175:101-116.e25 pubmed publisher
|
| Walker N, Mazzoni S, Vittal R, Fingar D, Lama V. c-Jun N-terminal kinase (JNK)-mediated induction of mSin1 expression and mTORC2 activation in mesenchymal cells during fibrosis. J Biol Chem. 2018;293:17229-17239 pubmed publisher
|
| Mason Osann E, Dai A, Floro J, Lock Y, Reiss M, Gali H, et al. Identification of a novel gene fusion in ALT positive osteosarcoma. Oncotarget. 2018;9:32868-32880 pubmed publisher
|
| Yang J, Hsu J, Park S, Li J, Oldham W, Beznoussenko G, et al. GAPDH inhibits intracellular pathways during starvation for cellular energy homeostasis. Nature. 2018;561:263-267 pubmed publisher
|
| Mallik M, Catinozzi M, Hug C, Zhang L, Wagner M, Bussmann J, et al. Xrp1 genetically interacts with the ALS-associated FUS orthologue caz and mediates its toxicity. J Cell Biol. 2018;217:3947-3964 pubmed publisher
|
| Miyamoto Y, Katayama S, Shigematsu N, Nishi A, Fukuda T. Striosome-based map of the mouse striatum that is conformable to both cortical afferent topography and uneven distributions of dopamine D1 and D2 receptor-expressing cells. Brain Struct Funct. 2018;223:4275-4291 pubmed publisher
|
| Wang H, Qiu Z, Liu B, Wu Y, Ren J, Liu Y, et al. PLK1 targets CtIP to promote microhomology-mediated end joining. Nucleic Acids Res. 2018;46:10724-10739 pubmed publisher
|
| Wei J, Yuan Y, Chen L, Xu Y, Zhang Y, Wang Y, et al. ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes. Nat Commun. 2018;9:3659 pubmed publisher
|
| Young P, Senkal C, Suchanek A, Grevengoed T, Lin D, Zhao L, et al. Long-chain acyl-CoA synthetase 1 interacts with key proteins that activate and direct fatty acids into niche hepatic pathways. J Biol Chem. 2018;293:16724-16740 pubmed publisher
|
| Xu W, Ma C, Zhang Q, Zhao R, Hu D, Zhang X, et al. PJA1 Coordinates with the SMC5/6 Complex To Restrict DNA Viruses and Episomal Genes in an Interferon-Independent Manner. J Virol. 2018;92: pubmed publisher
|
| Abbasi F, Miyata H, Shimada K, Morohoshi A, Nozawa K, Matsumura T, et al. RSPH6A is required for sperm flagellum formation and male fertility in mice. J Cell Sci. 2018;131: pubmed publisher
|
| Baker S, Ledwith M, Mehle A. Differential Splicing of ANP32A in Birds Alters Its Ability to Stimulate RNA Synthesis by Restricted Influenza Polymerase. Cell Rep. 2018;24:2581-2588.e4 pubmed publisher
|
| Sanders S, Ma Z, Hughes J, Riscoe B, Gibson G, Watson A, et al. CRISPR/Cas9-mediated gene knockin in the hydroid Hydractinia symbiolongicarpus. BMC Genomics. 2018;19:649 pubmed publisher
|
| Choi J, Fan C, Kim D, Sharif M, An H, Park Y. Elucidating the transactivation domain of the pleiotropic transcription factor Myrf. Sci Rep. 2018;8:13075 pubmed publisher
|
| Cristofani R, Montagnani Marelli M, Cicardi M, Fontana F, Marzagalli M, Limonta P, et al. Dual role of autophagy on docetaxel-sensitivity in prostate cancer cells. Cell Death Dis. 2018;9:889 pubmed publisher
|
| Crozet P, Navarro F, Willmund F, Mehrshahi P, Bakowski K, Lauersen K, et al. Birth of a Photosynthetic Chassis: A MoClo Toolkit Enabling Synthetic Biology in the Microalga Chlamydomonas reinhardtii. ACS Synth Biol. 2018;7:2074-2086 pubmed publisher
|
| Liu X, Cai S, Zhang C, Liu Z, Luo J, Xing B, et al. Deacetylation of NAT10 by Sirt1 promotes the transition from rRNA biogenesis to autophagy upon energy stress. Nucleic Acids Res. 2018;46:9601-9616 pubmed publisher
|
| Fröhlich K, Förstner K, Gitai Z. Post-transcriptional gene regulation by an Hfq-independent small RNA in Caulobacter crescentus. Nucleic Acids Res. 2018;46:10969-10982 pubmed publisher
|
| Gill M, Christova T, Zhang Y, Gregorieff A, Zhang L, Narimatsu M, et al. A feed forward loop enforces YAP/TAZ signaling during tumorigenesis. Nat Commun. 2018;9:3510 pubmed publisher
|
| Chakrabarty P, Li A, Ladd T, Strickland M, Koller E, Burgess J, et al. TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease. J Exp Med. 2018;215:2247-2264 pubmed publisher
|
| Thomas H, Zhang Y, Stefely J, Veiga S, Thomas G, Kozma S, et al. Mitochondrial Complex I Activity Is Required for Maximal Autophagy. Cell Rep. 2018;24:2404-2417.e8 pubmed publisher
|
| Sato T, Muramatsu T, Tanabe M, Inazawa J. Identification and characterization of transforming growth factor beta-induced in circulating tumor cell subline from pancreatic cancer cell line. Cancer Sci. 2018;109:3623-3633 pubmed publisher
|
| Zhang Y, Xue Y, Shi J, Ahn J, Mi W, Ali M, et al. The ZZ domain of p300 mediates specificity of the adjacent HAT domain for histone H3. Nat Struct Mol Biol. 2018;25:841-849 pubmed publisher
|
| Emperador Melero J, Huson V, Van Weering J, Bollmann C, Fischer von Mollard G, Toonen R, et al. Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi. Nat Commun. 2018;9:3421 pubmed publisher
|
| Jena K, Kolapalli S, Mehto S, Nath P, Das B, Sahoo P, et al. TRIM16 controls assembly and degradation of protein aggregates by modulating the p62-NRF2 axis and autophagy. EMBO J. 2018;37: pubmed publisher
|
| Mutlu B, Chen H, Moresco J, Orelo B, Yang B, Gaspar J, et al. Regulated nuclear accumulation of a histone methyltransferase times the onset of heterochromatin formation in C. elegans embryos. Sci Adv. 2018;4:eaat6224 pubmed publisher
|
| Bhakt P, Shivarathri R, Choudhary D, Borah S, Kaur R. Fluconazole-induced actin cytoskeleton remodeling requires phosphatidylinositol 3-phosphate 5-kinase in the pathogenic yeast Candida glabrata. Mol Microbiol. 2018;110:425-443 pubmed publisher
|
| Mahadevappa R, Neves H, Yuen S, Jameel M, Bai Y, Yuen H, et al. DNA Replication Licensing Protein MCM10 Promotes Tumor Progression and Is a Novel Prognostic Biomarker and Potential Therapeutic Target in Breast Cancer. Cancers (Basel). 2018;10: pubmed publisher
|
| Tigabu B, Ramanathan P, Ivanov A, Lin X, Ilinykh P, Parry C, et al. Phosphorylated VP30 of Marburg Virus Is a Repressor of Transcription. J Virol. 2018;92: pubmed publisher
|
| Yang K, Huang R, Fujihira H, Suzuki T, Yan N. N-glycanase NGLY1 regulates mitochondrial homeostasis and inflammation through NRF1. J Exp Med. 2018;215:2600-2616 pubmed publisher
|
| Nayak T, Trotter J, Sakry D. The Intracellular Cleavage Product of the NG2 Proteoglycan Modulates Translation and Cell-Cycle Kinetics via Effects on mTORC1/FMRP Signaling. Front Cell Neurosci. 2018;12:231 pubmed publisher
|
| Colecchia D, Dapporto F, Tronnolone S, Salvini L, Chiariello M. MAPK15 is part of the ULK complex and controls its activity to regulate early phases of the autophagic process. J Biol Chem. 2018;293:15962-15976 pubmed publisher
|
| Zhu Y, Luo Q, Davis S, Westra C, Vickers T, Fleckenstein J. Molecular Determinants of Enterotoxigenic Escherichia coli Heat-Stable Toxin Secretion and Delivery. Infect Immun. 2018;86: pubmed publisher
|
| Cloer E, Siesser P, Cousins E, Goldfarb D, Mowrey D, Harrison J, et al. p62-Dependent Phase Separation of Patient-Derived KEAP1 Mutations and NRF2. Mol Cell Biol. 2018;38: pubmed publisher
|
| Warkocki Z, Krawczyk P, Adamska D, Bijata K, Garcia Perez J, Dziembowski A. Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s. Cell. 2018;174:1537-1548.e29 pubmed publisher
|
| Li S, Tian Y, Wu K, Ye Y, Yu J, Zhang J, et al. Modulating plant growth-metabolism coordination for sustainable agriculture. Nature. 2018;560:595-600 pubmed publisher
|
| Piracha Z, Kwon H, Saeed U, Kim J, Jung J, Chwae Y, et al. Sirtuin 2 Isoform 1 Enhances Hepatitis B Virus RNA Transcription and DNA Synthesis through the AKT/GSK-3β/β-Catenin Signaling Pathway. J Virol. 2018;92: pubmed publisher
|
| Liu X, Hao S, Chen Z, Xu H, Wang H, Huang M, et al. The 5' Untranslated Region of Human Bocavirus Capsid Transcripts Regulates Viral mRNA Biogenesis and Alternative Translation. J Virol. 2018;92: pubmed publisher
|
| Lee S, North K, Kim E, Jang E, Obeng E, Lu S, et al. Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations. Cancer Cell. 2018;34:225-241.e8 pubmed publisher
|
| Chen Q, Kassab M, Dantzer F, Yu X. PARP2 mediates branched poly ADP-ribosylation in response to DNA damage. Nat Commun. 2018;9:3233 pubmed publisher
|
| Tan L, Zhang C, Hou X, Shao C, Lu Y, Zhou J, et al. The PEAT protein complexes are required for histone deacetylation and heterochromatin silencing. EMBO J. 2018;37: pubmed publisher
|
| Li J, Liu J, Lupino K, Liu X, Zhang L, Pei L. Growth Differentiation Factor 15 Maturation Requires Proteolytic Cleavage by PCSK3, -5, and -6. Mol Cell Biol. 2018;38: pubmed publisher
|
| Le François B, Zhang L, Mahajan G, Stockmeier C, Friedman E, Albert P. A Novel Alternative Splicing Mechanism That Enhances Human 5-HT1A Receptor RNA Stability Is Altered in Major Depression. J Neurosci. 2018;38:8200-8210 pubmed publisher
|
| Prinz E, Aviram S, Aronheim A. WDR62 mediates TNFα-dependent JNK activation via TRAF2-MLK3 axis. Mol Biol Cell. 2018;29:2470-2480 pubmed publisher
|
| Bagchi R, Ferguson B, Stratton M, Hu T, Cavasin M, Sun L, et al. HDAC11 suppresses the thermogenic program of adipose tissue via BRD2. JCI Insight. 2018;3: pubmed publisher
|
| Schlueter J, Mikawa T. Body Cavity Development Is Guided by Morphogen Transfer between Germ Layers. Cell Rep. 2018;24:1456-1463 pubmed publisher
|
| Yin Y, Garcia M, Novak A, Saunders A, Ank R, Nam A, et al. Surf4 (Erv29p) binds amino-terminal tripeptide motifs of soluble cargo proteins with different affinities, enabling prioritization of their exit from the endoplasmic reticulum. PLoS Biol. 2018;16:e2005140 pubmed publisher
|
| Piragyte I, Clapes T, Polyzou A, Klein Geltink R, Lefkopoulos S, Yin N, et al. A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways. Nat Commun. 2018;9:3090 pubmed publisher
|
| Tran K, Jethmalani Y, Jaiswal D, Green E. Set4 is a chromatin-associated protein, promotes survival during oxidative stress, and regulates stress response genes in yeast. J Biol Chem. 2018;293:14429-14443 pubmed publisher
|
| Zhu L, Jones C. The canonical Wnt/β-catenin signaling pathway stimulates herpes simplex virus 1 productive infection. Virus Res. 2018;256:29-37 pubmed publisher
|
| Liu Q, Chen L, Aguilar H, Chou K. A stochastic assembly model for Nipah virus revealed by super-resolution microscopy. Nat Commun. 2018;9:3050 pubmed publisher
|
| Wang Q, Yan R, Pinnell N, McCarter A, Oh Y, Liu Y, et al. Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell development. Blood. 2018;: pubmed publisher
|
| Hiramuki Y, Tapscott S. Identification of SMCHD1 domains for nuclear localization, homo-dimerization, and protein cleavage. Skelet Muscle. 2018;8:24 pubmed publisher
|
| Xiong Y, Torsoni A, Wu F, Shen H, Liu Y, Zhong X, et al. Hepatic NF-kB-inducing kinase (NIK) suppresses mouse liver regeneration in acute and chronic liver diseases. elife. 2018;7: pubmed publisher
|
| Park R, Miller G. Epstein-Barr Virus-Induced Nodules on Viral Replication Compartments Contain RNA Processing Proteins and a Viral Long Noncoding RNA. J Virol. 2018;92: pubmed publisher
|
| Tsai M, Chiang M, Tsai D, Yang C, Hou H, Li Y, et al. Galectin-1 Restricts Vascular Smooth Muscle Cell Motility Via Modulating Adhesion Force and Focal Adhesion Dynamics. Sci Rep. 2018;8:11497 pubmed publisher
|
| Luo W, Guo F, McMahon A, Couvertier S, Jin H, Diaz M, et al. NonA and CPX Link the Circadian Clockwork to Locomotor Activity in Drosophila. Neuron. 2018;99:768-780.e3 pubmed publisher
|
| Zhang L, Serra Cardona A, Zhou H, Wang M, Yang N, Zhang Z, et al. Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109. Cell. 2018;174:818-830.e11 pubmed publisher
|
| Li W, Wong C, Zhang X, Kang W, Nakatsu G, Zhao Q, et al. CAB39L elicited an anti-Warburg effect via a LKB1-AMPK-PGC1α axis to inhibit gastric tumorigenesis. Oncogene. 2018;37:6383-6398 pubmed publisher
|
| Risher W, Kim N, Koh S, Choi J, Mitev P, Spence E, et al. Thrombospondin receptor α2δ-1 promotes synaptogenesis and spinogenesis via postsynaptic Rac1. J Cell Biol. 2018;217:3747-3765 pubmed publisher
|
| Simandi Z, Pajer K, Károlyi K, Sieler T, Jiang L, Kolostyak Z, et al. Arginine Methyltransferase PRMT8 Provides Cellular Stress Tolerance in Aging Motoneurons. J Neurosci. 2018;38:7683-7700 pubmed publisher
|
| Zhang Y, Tan L, Yang Q, Li C, Liou Y. The microtubule-associated protein HURP recruits the centrosomal protein TACC3 to regulate K-fiber formation and support chromosome congression. J Biol Chem. 2018;293:15733-15747 pubmed publisher
|
| Sengupta S, Sun S, Huang K, Oh C, Bailey M, Varghese R, et al. Integrative omics analyses broaden treatment targets in human cancer. Genome Med. 2018;10:60 pubmed publisher
|
| Wilson D, Scholl B, Fitzpatrick D. Differential tuning of excitation and inhibition shapes direction selectivity in ferret visual cortex. Nature. 2018;560:97-101 pubmed publisher
|
| Du L, Zhao Z, Suraokar M, Shelton S, Ma X, Hsiao T, et al. LMO1 functions as an oncogene by regulating TTK expression and correlates with neuroendocrine differentiation of lung cancer. Oncotarget. 2018;9:29601-29618 pubmed publisher
|
| Xia W, Su L, Jiao J. Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress. J Cell Biol. 2018;217:3464-3479 pubmed publisher
|
| Uebel C, Anderson D, Mandarino L, Manage K, Aynaszyan S, Phillips C. Distinct regions of the intrinsically disordered protein MUT-16 mediate assembly of a small RNA amplification complex and promote phase separation of Mutator foci. PLoS Genet. 2018;14:e1007542 pubmed publisher
|
| Nie X, Kitaoka S, Tanaka K, Segi Nishida E, Imoto Y, Ogawa A, et al. The Innate Immune Receptors TLR2/4 Mediate Repeated Social Defeat Stress-Induced Social Avoidance through Prefrontal Microglial Activation. Neuron. 2018;99:464-479.e7 pubmed publisher
|
| Xiao D, Liu X, Zhang M, Zou M, Deng Q, Sun D, et al. Direct reprogramming of fibroblasts into neural stem cells by single non-neural progenitor transcription factor Ptf1a. Nat Commun. 2018;9:2865 pubmed publisher
|
| Yuan J, Ng W, Yap J, Chia B, Huang X, Wang M, et al. The AMPK inhibitor overcomes the paradoxical effect of RAF inhibitors through blocking phospho-Ser-621 in the C terminus of CRAF. J Biol Chem. 2018;293:14276-14284 pubmed publisher
|
| Eubelen M, Bostaille N, Cabochette P, Gauquier A, Tebabi P, Dumitru A, et al. A molecular mechanism for Wnt ligand-specific signaling. Science. 2018;361: pubmed publisher
|
| Chen K, Stroup E, Budhipramono A, Rakheja D, Nichols Vinueza D, Xu L, et al. Mutations in microRNA processing genes in Wilms tumors derepress the IGF2 regulator PLAG1. Genes Dev. 2018;32:996-1007 pubmed publisher
|
| Mirman Z, Lottersberger F, Takai H, Kibe T, Gong Y, Takai K, et al. 53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polα-dependent fill-in. Nature. 2018;560:112-116 pubmed publisher
|
| Wang H, Li S, Oaks J, Ren J, Li L, Wu X. The concerted roles of FANCM and Rad52 in the protection of common fragile sites. Nat Commun. 2018;9:2791 pubmed publisher
|
| Sun J, Liu Y, Jia Y, Hao X, Lin W, Tran J, et al. UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity. elife. 2018;7: pubmed publisher
|
| Xiao Q, Dong M, Cheng F, Mao F, Zong W, Wu K, et al. LRIG2 promotes the proliferation and cell cycle progression of glioblastoma cells in vitro and in vivo through enhancing PDGFRβ signaling. Int J Oncol. 2018;53:1069-1082 pubmed publisher
|
| Asada S, Goyama S, Inoue D, Shikata S, Takeda R, Fukushima T, et al. Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis. Nat Commun. 2018;9:2733 pubmed publisher
|
| Nowsheen S, Aziz K, Luo K, Deng M, Qin B, Yuan J, et al. ZNF506-dependent positive feedback loop regulates H2AX signaling after DNA damage. Nat Commun. 2018;9:2736 pubmed publisher
|
| Ma X, Liu K, Li J, Li H, Li J, Liu Y, et al. A non-canonical GTPase interaction enables ORP1L-Rab7-RILP complex formation and late endosome positioning. J Biol Chem. 2018;293:14155-14164 pubmed publisher
|
| Guillotte M, Gillespie J, Chandler C, Rahman M, Ernst R, Azad A. Rickettsia Lipid A Biosynthesis Utilizes the Late Acyltransferase LpxJ for Secondary Fatty Acid Addition. J Bacteriol. 2018;200: pubmed publisher
|
| Gu T, Lin X, Cullen S, Luo M, Jeong M, Estecio M, et al. DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells. Genome Biol. 2018;19:88 pubmed publisher
|
| Herren M, Shrestha N, Wyss M, Zurbriggen A, Plattet P. Regulatory Role of the Morbillivirus Attachment Protein Head-to-Stalk Linker Module in Membrane Fusion Triggering. J Virol. 2018;92: pubmed publisher
|
| Wu F, Gao P, Wu W, Wang Z, Yang J, Di J, et al. STK25-induced inhibition of aerobic glycolysis via GOLPH3-mTOR pathway suppresses cell proliferation in colorectal cancer. J Exp Clin Cancer Res. 2018;37:144 pubmed publisher
|
| Kasu Y, Alemu S, Lamari A, Loew N, Brower C. The N Termini of TAR DNA-Binding Protein 43 (TDP43) C-Terminal Fragments Influence Degradation, Aggregation Propensity, and Morphology. Mol Cell Biol. 2018;38: pubmed publisher
|
| Deshpande A, Collins K. Mechanisms of template handling and pseudoknot folding in human telomerase and their manipulation to expand the sequence repertoire of processive repeat synthesis. Nucleic Acids Res. 2018;46:7886-7901 pubmed publisher
|
| Róna G, Roberti D, Yin Y, Pagan J, Homer H, Sassani E, et al. PARP1-dependent recruitment of the FBXL10-RNF68-RNF2 ubiquitin ligase to sites of DNA damage controls H2A.Z loading. elife. 2018;7: pubmed publisher
|
| Balakrishnan S, Basu U, Shinde D, Thakur R, Jaiswal M, Raghu P. Regulation of PI4P levels by PI4KIIIα during G-protein-coupled PLC signaling in Drosophila photoreceptors. J Cell Sci. 2018;131: pubmed publisher
|
| Tojkander S, Ciuba K, Lappalainen P. CaMKK2 Regulates Mechanosensitive Assembly of Contractile Actin Stress Fibers. Cell Rep. 2018;24:11-19 pubmed publisher
|
| Andrews A, McCartney H, Errington T, D Andrea A, Macara I. A senataxin-associated exonuclease SAN1 is required for resistance to DNA interstrand cross-links. Nat Commun. 2018;9:2592 pubmed publisher
|
| Liang H, Ge F, Xu Y, Xiao J, Zhou Z, Liu R, et al. miR-153 inhibits the migration and the tube formation of endothelial cells by blocking the paracrine of angiopoietin 1 in breast cancer cells. Angiogenesis. 2018;21:849-860 pubmed publisher
|
| Guo J, Liu X, Wu C, Hu J, Peng K, Wu L, et al. The transmembrane nucleoporin Pom121 ensures efficient HIV-1 pre-integration complex nuclear import. Virology. 2018;521:169-174 pubmed publisher
|
| Intlekofer A, Shih A, Wang B, Nazir A, Rustenburg A, Albanese S, et al. Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations. Nature. 2018;559:125-129 pubmed publisher
|
| Zhang Y, Burberry A, Wang J, Sandoe J, Ghosh S, Udeshi N, et al. The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis. Genes Dev. 2018;32:929-943 pubmed publisher
|
| Jin Y, You L, Kim H, Lee H. Telomerase Reverse Transcriptase Contains a BH3-Like Motif and Interacts with BCL-2 Family Members. Mol Cells. 2018;41:684-694 pubmed publisher
|
| Beránek V, Reinkemeier C, Zhang M, Liang A, Kym G, Chin J. Genetically Encoded Protein Phosphorylation in Mammalian Cells. Cell Chem Biol. 2018;25:1067-1074.e5 pubmed publisher
|
| Higgs M, Sato K, Reynolds J, Begum S, Bayley R, Goula A, et al. Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2. Mol Cell. 2018;71:25-41.e6 pubmed publisher
|
| Wang L, Cho Y, Tang Y, Wang J, Park J, Wu Y, et al. PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy. Cell Res. 2018;28:787-802 pubmed publisher
|
| Kowalski L, Bragoszewski P, Khmelinskii A, Glow E, Knop M, Chacinska A. Determinants of the cytosolic turnover of mitochondrial intermembrane space proteins. BMC Biol. 2018;16:66 pubmed publisher
|
| Caridi C, D Agostino C, Ryu T, Zapotoczny G, Delabaere L, Li X, et al. Nuclear F-actin and myosins drive relocalization of heterochromatic breaks. Nature. 2018;559:54-60 pubmed publisher
|
| Chen S, Cui Y, Parashar S, Novick P, Ferro Novick S. ER-phagy requires Lnp1, a protein that stabilizes rearrangements of the ER network. Proc Natl Acad Sci U S A. 2018;115:E6237-E6244 pubmed publisher
|
| Adachi K, Kopp W, Wu G, Heising S, Greber B, Stehling M, et al. Esrrb Unlocks Silenced Enhancers for Reprogramming to Naive Pluripotency. Cell Stem Cell. 2018;23:266-275.e6 pubmed publisher
|
| Bertalovitz A, Badhey M, McDonald T. Synonymous nucleotide modification of the KCNH2 gene affects both mRNA characteristics and translation of the encoded hERG ion channel. J Biol Chem. 2018;293:12120-12136 pubmed publisher
|
| Laranjeira Silva M, Wang W, Samuel T, Maeda F, Michailowsky V, Hamza I, et al. A MFS-like plasma membrane transporter required for Leishmania virulence protects the parasites from iron toxicity. PLoS Pathog. 2018;14:e1007140 pubmed publisher
|
| Song J, Zhang X, Ge Q, Yuan C, Chu L, Liang H, et al. CRISPR/Cas9-mediated knockout of HBsAg inhibits proliferation and tumorigenicity of HBV-positive hepatocellular carcinoma cells. J Cell Biochem. 2018;119:8419-8431 pubmed publisher
|
| Meshram C, Agback P, Shiliaev N, Urakova N, Mobley J, Agback T, et al. Multiple Host Factors Interact with the Hypervariable Domain of Chikungunya Virus nsP3 and Determine Viral Replication in Cell-Specific Mode. J Virol. 2018;92: pubmed publisher
|
| Fujita T, Yuno M, Fujii H. An enChIP system for the analysis of bacterial genome functions. BMC Res Notes. 2018;11:387 pubmed publisher
|
| Sevinsky C, Khan F, Kokabee L, Darehshouri A, Maddipati K, Conklin D. NDRG1 regulates neutral lipid metabolism in breast cancer cells. Breast Cancer Res. 2018;20:55 pubmed publisher
|
| Ihry R, Worringer K, Salick M, Frias E, Ho D, Theriault K, et al. p53 inhibits CRISPR-Cas9 engineering in human pluripotent stem cells. Nat Med. 2018;24:939-946 pubmed publisher
|
| Chu H, Chan C, Zhang X, Wang Y, Yuan S, Zhou J, et al. Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells. J Biol Chem. 2018;293:11709-11726 pubmed publisher
|
| Li Q, Li Y, Liang L, Li J, Luo D, Liu Q, et al. Klotho negatively regulated aerobic glycolysis in colorectal cancer via ERK/HIF1α axis. Cell Commun Signal. 2018;16:26 pubmed publisher
|
| Weyn Vanhentenryck S, Feng H, Ustianenko D, Duffié R, Yan Q, Jacko M, et al. Precise temporal regulation of alternative splicing during neural development. Nat Commun. 2018;9:2189 pubmed publisher
|
| Coursey T, Milutinović M, Regedanz E, Brkljacic J, Bisaro D. Arabidopsis Histone Reader EMSY-LIKE 1 Binds H3K36 and Suppresses Geminivirus Infection. J Virol. 2018;92: pubmed publisher
|
| Hua X, Li B, Song L, Hu C, Li X, Wang D, et al. Stimulator of interferon genes (STING) provides insect antiviral immunity by promoting Dredd caspase-mediated NF-κB activation. J Biol Chem. 2018;293:11878-11890 pubmed publisher
|
| Millership S, Da Silva Xavier G, Choudhury A, Bertazzo S, Chabosseau P, Pedroni S, et al. Neuronatin regulates pancreatic β cell insulin content and secretion. J Clin Invest. 2018;128:3369-3381 pubmed publisher
|
| Franqui Machin R, Hao M, Bai H, Gu Z, Zhan X, Habelhah H, et al. Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma. J Clin Invest. 2018;: pubmed publisher
|
| Rousseaux M, Revelli J, Vázquez Vélez G, Kim J, Craigen E, Gonzales K, et al. Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau. elife. 2018;7: pubmed publisher
|
| Galvão J, Iwao K, Apara A, Wang Y, Ashouri M, Shah T, et al. The Krüppel-Like Factor Gene Target Dusp14 Regulates Axon Growth and Regeneration. Invest Ophthalmol Vis Sci. 2018;59:2736-2747 pubmed publisher
|
| Kauppila J, Bonekamp N, Mourier A, Isokallio M, Just A, Kauppila T, et al. Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res. 2018;46:6642-6669 pubmed publisher
|
| Bao L, Chen Y, Lai H, Wu S, Wang J, Hatanpaa K, et al. Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration. Nucleic Acids Res. 2018;46:6576-6591 pubmed publisher
|
| Mefferd A, Bogerd H, Irwan I, Cullen B. Insights into the mechanisms underlying the inactivation of HIV-1 proviruses by CRISPR/Cas. Virology. 2018;520:116-126 pubmed publisher
|
| Wei R, Wong J, Lyu P, Xi X, Tong O, Zhang S, et al. In vitro and clinical data analysis of Osteopontin as a prognostic indicator in colorectal cancer. J Cell Mol Med. 2018;22:4097-4105 pubmed publisher
|
| Bricambert J, Alves Guerra M, Esteves P, Prip Buus C, Bertrand Michel J, Guillou H, et al. The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity. Nat Commun. 2018;9:2092 pubmed publisher
|
| Yoo J, Kang H, Broaddus R, Risinger J, Choi K, Kim T. MIG-6 suppresses endometrial epithelial cell proliferation by inhibiting phospho-AKT. BMC Cancer. 2018;18:605 pubmed publisher
|
| Wei X, Zhang K, Qin H, Zhu J, Qin Q, Yu Y, et al. GMDS knockdown impairs cell proliferation and survival in human lung adenocarcinoma. BMC Cancer. 2018;18:600 pubmed publisher
|
| Dimitrova E, Kondo T, Feldmann A, Nakayama M, Koseki Y, Konietzny R, et al. FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment. elife. 2018;7: pubmed publisher
|
| Ito Ishida A, Yamalanchili H, Shao Y, BAKER S, Heckman L, Lavery L, et al. Genome-wide distribution of linker histone H1.0 is independent of MeCP2. Nat Neurosci. 2018;21:794-798 pubmed publisher
|
| Tsuchiya M, Hara Y, Okuda M, Itoh K, Nishioka R, Shiomi A, et al. Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation. Nat Commun. 2018;9:2049 pubmed publisher
|
| Wang R, Li C, Qiao P, Xue Y, Zheng X, Chen H, et al. OGG1-initiated base excision repair exacerbates oxidative stress-induced parthanatos. Cell Death Dis. 2018;9:628 pubmed publisher
|
| Vannocci T, Notario Manzano R, Beccalli O, Bettegazzi B, Grohovaz F, Cinque G, et al. Adding a temporal dimension to the study of Friedreich's ataxia: the effect of frataxin overexpression in a human cell model. Dis Model Mech. 2018;11: pubmed publisher
|
| Matsui T, Jiang P, Nakano S, Sakamaki Y, Yamamoto H, Mizushima N. Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17. J Cell Biol. 2018;217:2633-2645 pubmed publisher
|
| Skucha A, Ebner J, Schmöllerl J, Roth M, Eder T, César Razquin A, et al. MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity. Nat Commun. 2018;9:1983 pubmed publisher
|
| Sigmund F, Massner C, Erdmann P, Stelzl A, Rolbieski H, Desai M, et al. Bacterial encapsulins as orthogonal compartments for mammalian cell engineering. Nat Commun. 2018;9:1990 pubmed publisher
|
| Gu P, Jia S, Takasugi T, Smith E, Nandakumar J, HENDRICKSON E, et al. CTC1-STN1 coordinates G- and C-strand synthesis to regulate telomere length. Aging Cell. 2018;:e12783 pubmed publisher
|
| Huang C, Liang D, Tatomer D, Wilusz J. A length-dependent evolutionarily conserved pathway controls nuclear export of circular RNAs. Genes Dev. 2018;32:639-644 pubmed publisher
|
| Chen Y, Chang I, Liu H, Ma C, Kuo Y, Shih C, et al. Tumor-associated intronic editing of HNRPLL generates a novel splicing variant linked to cell proliferation. J Biol Chem. 2018;293:10158-10171 pubmed publisher
|
| Murthy T, Bluemn T, Gupta A, Reimer M, Rao S, Pillai M, et al. Cyclin-dependent kinase 1 (CDK1) and CDK2 have opposing roles in regulating interactions of splicing factor 3B1 with chromatin. J Biol Chem. 2018;293:10220-10234 pubmed publisher
|
| Periyasamy P, Thangaraj A, Guo M, Hu G, Callen S, Buch S. Epigenetic Promoter DNA Methylation of miR-124 Promotes HIV-1 Tat-Mediated Microglial Activation via MECP2-STAT3 Axis. J Neurosci. 2018;38:5367-5383 pubmed publisher
|
| Liao J, Jiang J, Jun H, Qiao X, Emont M, Kim D, et al. HDAC3-Selective Inhibition Activates Brown and Beige Fat Through PRDM16. Endocrinology. 2018;159:2520-2527 pubmed publisher
|
| Srinivasan M, Scheinost J, Petela N, Gligoris T, Wissler M, Ogushi S, et al. The Cohesin Ring Uses Its Hinge to Organize DNA Using Non-topological as well as Topological Mechanisms. Cell. 2018;173:1508-1519.e18 pubmed publisher
|
| Olesen C, Vogensen J, Axholm I, Severin M, Schnipper J, Pedersen I, et al. Trafficking, localization and degradation of the Na+,HCO3- co-transporter NBCn1 in kidney and breast epithelial cells. Sci Rep. 2018;8:7435 pubmed publisher
|
| Zur Lage P, Stefanopoulou P, Styczynska Soczka K, Quinn N, Mali G, von Kriegsheim A, et al. Ciliary dynein motor preassembly is regulated by Wdr92 in association with HSP90 co-chaperone, R2TP. J Cell Biol. 2018;217:2583-2598 pubmed publisher
|
| Huang H, Kapeli K, Jin W, Wong Y, Arumugam T, Koh J, et al. Tissue-selective restriction of RNA editing of CaV1.3 by splicing factor SRSF9. Nucleic Acids Res. 2018;46:7323-7338 pubmed publisher
|
| Pinarbasi E, Cagatay T, Fung H, Li Y, Chook Y, Thomas P. Active nuclear import and passive nuclear export are the primary determinants of TDP-43 localization. Sci Rep. 2018;8:7083 pubmed publisher
|
| Yuan F, Xu C, Li G, Tong T. Nucleolar TRF2 attenuated nucleolus stress-induced HCC cell-cycle arrest by altering rRNA synthesis. Cell Death Dis. 2018;9:518 pubmed publisher
|
| Qian M, Liu Z, Peng L, Tang X, Meng F, Ao Y, et al. Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria. elife. 2018;7: pubmed publisher
|
| Gu H, Do D, Liu X, Xu L, Su Y, Nah J, et al. The STAT3 Target Mettl8 Regulates Mouse ESC Differentiation via Inhibiting the JNK Pathway. Stem Cell Reports. 2018;10:1807-1820 pubmed publisher
|
| Shah N, Kumar S, Zaman N, Pan C, Bloodworth J, Lei W, et al. TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth. Nat Commun. 2018;9:1696 pubmed publisher
|
| Rayaprolu V, Royal P, Stengel K, Sandoz G, Kohout S. Dimerization of the voltage-sensing phosphatase controls its voltage-sensing and catalytic activity. J Gen Physiol. 2018;150:683-696 pubmed publisher
|
| Numata A, Kwok H, Kawasaki A, Li J, Zhou Q, Kerry J, et al. The basic helix-loop-helix transcription factor SHARP1 is an oncogenic driver in MLL-AF6 acute myelogenous leukemia. Nat Commun. 2018;9:1622 pubmed publisher
|
| Hong S, Song W, Zushin P, Liu B, Jedrychowski M, Mina A, et al. Phosphorylation of Beta-3 adrenergic receptor at serine 247 by ERK MAP kinase drives lipolysis in obese adipocytes. Mol Metab. 2018;12:25-38 pubmed publisher
|
| Fang J, Yang J, Wu X, Zhang G, Li T, Wang X, et al. Metformin alleviates human cellular aging by upregulating the endoplasmic reticulum glutathione peroxidase 7. Aging Cell. 2018;17:e12765 pubmed publisher
|
| Nagase R, Inoue D, Pastore A, Fujino T, Hou H, Yamasaki N, et al. Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation. J Exp Med. 2018;215:1729-1747 pubmed publisher
|
| Venkataraman A, Yang K, Irizarry J, Mackiewicz M, Mita P, Kuang Z, et al. A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors. Nat Methods. 2018;: pubmed publisher
|
| Verma R, Reichermeier K, Burroughs A, Oania R, Reitsma J, Aravind L, et al. Vms1 and ANKZF1 peptidyl-tRNA hydrolases release nascent chains from stalled ribosomes. Nature. 2018;557:446-451 pubmed publisher
|
| Jia J, Abudu Y, Claude Taupin A, Gu Y, Kumar S, Choi S, et al. Galectins Control mTOR in Response to Endomembrane Damage. Mol Cell. 2018;70:120-135.e8 pubmed publisher
|
| Gong L, Liu F, Xiong Z, Qi R, Luo Z, Gong X, et al. Heterochromatin protects retinal pigment epithelium cells from oxidative damage by silencing p53 target genes. Proc Natl Acad Sci U S A. 2018;115:E3987-E3995 pubmed publisher
|
| Ray T, Roy S, Kozlowski C, Wang J, Cafaro J, Hulbert S, et al. Formation of retinal direction-selective circuitry initiated by starburst amacrine cell homotypic contact. elife. 2018;7: pubmed publisher
|
| Cao L, Wang S, Zhang Y, Wong K, Nakatsu G, Wang X, et al. Zinc-finger protein 471 suppresses gastric cancer through transcriptionally repressing downstream oncogenic PLS3 and TFAP2A. Oncogene. 2018;37:3601-3616 pubmed publisher
|
| Lei L, Cao W, Liu L, Das U, Wu Y, Liu G, et al. Multilevel Differential Control of Hormone Gene Expression Programs by hnRNP L and LL in Pituitary Cells. Mol Cell Biol. 2018;38: pubmed publisher
|
| Liu N, Hargreaves V, Zhu Q, Kurland J, Hong J, Kim W, et al. Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch. Cell. 2018;173:430-442.e17 pubmed publisher
|
| Zhou P, Ding X, Wan X, Liu L, Yuan X, Zhang W, et al. MLL5 suppresses antiviral innate immune response by facilitating STUB1-mediated RIG-I degradation. Nat Commun. 2018;9:1243 pubmed publisher
|
| Jung M, Häberle B, Tschaikowsky T, Wittmann M, Balta E, Stadler V, et al. Analysis of the expression pattern of the schizophrenia-risk and intellectual disability gene TCF4 in the developing and adult brain suggests a role in development and plasticity of cortical and hippocampal neurons. Mol Autism. 2018;9:20 pubmed publisher
|
| Luciano A, Zhou W, Santana J, Kyriakides C, Velazquez H, Sessa W. CLOCK phosphorylation by AKT regulates its nuclear accumulation and circadian gene expression in peripheral tissues. J Biol Chem. 2018;293:9126-9136 pubmed publisher
|
| O Geen H, Ren C, Coggins N, Bates S, Segal D. Unexpected binding behaviors of bacterial Argonautes in human cells cast doubts on their use as targetable gene regulators. PLoS ONE. 2018;13:e0193818 pubmed publisher
|
| Wai D, Szyszka T, Campbell A, Kwong C, Wilkinson White L, Silva A, et al. The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators. J Biol Chem. 2018;293:7160-7175 pubmed publisher
|
| Zhang Y, Wang S, Kang W, Liu C, Dong Y, Ren F, et al. CREPT facilitates colorectal cancer growth through inducing Wnt/β-catenin pathway by enhancing p300-mediated β-catenin acetylation. Oncogene. 2018;37:3485-3500 pubmed publisher
|
| Bergiers I, Andrews T, Vargel Bölükbaşı Ö, Buness A, Janosz E, Lopez Anguita N, et al. Single-cell transcriptomics reveals a new dynamical function of transcription factors during embryonic hematopoiesis. elife. 2018;7: pubmed publisher
|
| Amaya Ramirez C, Hubbe P, Mandel N, Béthune J. 4EHP-independent repression of endogenous mRNAs by the RNA-binding protein GIGYF2. Nucleic Acids Res. 2018;46:5792-5808 pubmed publisher
|
| Teratani T, Tomita K, Suzuki T, Furuhashi H, Irie R, Nishikawa M, et al. Aortic carboxypeptidase-like protein, a WNT ligand, exacerbates nonalcoholic steatohepatitis. J Clin Invest. 2018;128:1581-1596 pubmed publisher
|
| Burstein S, Kim H, Fels J, Qian L, Zhang S, Zhou P, et al. Estrogen receptor beta modulates permeability transition in brain mitochondria. Biochim Biophys Acta Bioenerg. 2018;1859:423-433 pubmed publisher
|
| Kim M, Kim J, Son S, Lim C, Eum H, Ha D, et al. Mbd2-CP2c loop drives adult-type globin gene expression and definitive erythropoiesis. Nucleic Acids Res. 2018;46:4933-4949 pubmed publisher
|
| Fang Z, Cao B, Liao J, Deng J, Plummer K, Liao P, et al. SPIN1 promotes tumorigenesis by blocking the uL18 (universal large ribosomal subunit protein 18)-MDM2-p53 pathway in human cancer. elife. 2018;7: pubmed publisher
|
| Eguether T, Cordelières F, Pazour G. Intraflagellar transport is deeply integrated in hedgehog signaling. Mol Biol Cell. 2018;29:1178-1189 pubmed publisher
|
| Li J, Perfetto M, Neuner R, Bahudhanapati H, Christian L, Mathavan K, et al. Xenopus ADAM19 regulates Wnt signaling and neural crest specification by stabilizing ADAM13. Development. 2018;145: pubmed publisher
|
| Peng Y, Shen T, Chen Y, Mersmann H, Liu B, Ding S. Adiponectin and adiponectin receptor 1 overexpression enhance inflammatory bowel disease. J Biomed Sci. 2018;25:24 pubmed publisher
|
| Knuckles P, Lence T, Haussmann I, Jacob D, Kreim N, Carl S, et al. Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d. Genes Dev. 2018;32:415-429 pubmed publisher
|
| Campbell A, Shadle S, Jagannathan S, Lim J, Resnick R, Tawil R, et al. NuRD and CAF-1-mediated silencing of the D4Z4 array is modulated by DUX4-induced MBD3L proteins. elife. 2018;7: pubmed publisher
|
| Podewin T, Ast J, Broichhagen J, Fine N, Nasteska D, Leippe P, et al. Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology. ACS Cent Sci. 2018;4:166-179 pubmed publisher
|
| Zhang L, Köhler S, Rillo Bohn R, Dernburg A. A compartmentalized signaling network mediates crossover control in meiosis. elife. 2018;7: pubmed publisher
|
| Narayanan P, Hütte M, Kudryasheva G, Taberner F, Lechner S, Rehfeldt F, et al. Myotubularin related protein-2 and its phospholipid substrate PIP2 control Piezo2-mediated mechanotransduction in peripheral sensory neurons. elife. 2018;7: pubmed publisher
|
| Cairns L, Tran T, Fowl B, Patterson A, Kim Y, Bothner B, et al. Salvador has an extended SARAH domain that mediates binding to Hippo kinase. J Biol Chem. 2018;293:5532-5543 pubmed publisher
|
| Hovsepian J, Albanèse V, Becuwe M, Ivashov V, Teis D, Léon S. The yeast arrestin-related protein Bul1 is a novel actor of glucose-induced endocytosis. Mol Biol Cell. 2018;: pubmed publisher
|
| Peng J, Santiago I, Ahn C, Gur B, Tsui C, Su Z, et al. Drosophila Fezf coordinates laminar-specific connectivity through cell-intrinsic and cell-extrinsic mechanisms. elife. 2018;7: pubmed publisher
|
| Wang Q, Yu J, Kadungure T, Beyene J, Zhang H, Lu Q. ARMMs as a versatile platform for intracellular delivery of macromolecules. Nat Commun. 2018;9:960 pubmed publisher
|
| Kramer N, Haney M, Morgens D, Jovicic A, Couthouis J, Li A, et al. CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity. Nat Genet. 2018;50:603-612 pubmed publisher
|
| Hsu C, Lee E, Gordon K, Paz E, Shen W, Ohnishi K, et al. MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB. Nat Commun. 2018;9:942 pubmed publisher
|
| Tsuchiya Y, Saito M, Kadokura H, Miyazaki J, Tashiro F, Imagawa Y, et al. IRE1-XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells. J Cell Biol. 2018;217:1287-1301 pubmed publisher
|
| Sobol M, Krausová A, Yildirim S, Kalasová I, Fáberová V, Vrkoslav V, et al. Nuclear phosphatidylinositol 4,5-bisphosphate islets contribute to efficient RNA polymerase II-dependent transcription. J Cell Sci. 2018;131: pubmed publisher
|
| Dong L, Yu L, Bai C, Liu L, Long H, Shi L, et al. USP27-mediated Cyclin E stabilization drives cell cycle progression and hepatocellular tumorigenesis. Oncogene. 2018;37:2702-2713 pubmed publisher
|
| Yokoyama C, Baldridge M, Leung D, Zhao G, Desai C, Liu T, et al. LysMD3 is a type II membrane protein without an in vivo role in the response to a range of pathogens. J Biol Chem. 2018;293:6022-6038 pubmed publisher
|
| Cheng M, Niu Y, Fan J, Chi X, Liu X, Yang W. Interferon down-regulation of miR-1225-3p as an antiviral mechanism through modulating Grb2-associated binding protein 3 expression. J Biol Chem. 2018;293:5975-5986 pubmed publisher
|
| Koga R, Kubota M, Hashiguchi T, Yanagi Y, Ohno S. Annexin A2 Mediates the Localization of Measles Virus Matrix Protein at the Plasma Membrane. J Virol. 2018;92: pubmed publisher
|
| Shi W, Riquelme M, Gu S, Jiang J. Connexin hemichannels mediate glutathione transport and protect lens fiber cells from oxidative stress. J Cell Sci. 2018;131: pubmed publisher
|
| Guallar D, Bi X, Pardavila J, Huang X, Sáenz C, Shi X, et al. RNA-dependent chromatin targeting of TET2 for endogenous retrovirus control in pluripotent stem cells. Nat Genet. 2018;50:443-451 pubmed publisher
|
| Ferrandiz N, Barroso C, Telecan O, Shao N, Kim H, Testori S, et al. Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis. Nat Commun. 2018;9:834 pubmed publisher
|
| Yu M, Arshad M, Wang W, Zhao D, Xu L, Zhou L. LRRK2 mediated Rab8a phosphorylation promotes lipid storage. Lipids Health Dis. 2018;17:34 pubmed publisher
|
| Fujita T, Yuno M, Fujii H. enChIP systems using different CRISPR orthologues and epitope tags. BMC Res Notes. 2018;11:154 pubmed publisher
|
| Li X, Zhang Z, Zhang Y, Cao Y, Wei H, Wu Z. Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16INK4a inactivation. J Exp Clin Cancer Res. 2018;37:39 pubmed publisher
|
| Alberti C, Manzenreither R, Sowemimo I, Burkard T, Wang J, Mahofsky K, et al. Cell-type specific sequencing of microRNAs from complex animal tissues. Nat Methods. 2018;15:283-289 pubmed publisher
|
| Huang L, Wang Z, Narayanan N, Yang Y. Arginine methylation of the C-terminus RGG motif promotes TOP3B topoisomerase activity and stress granule localization. Nucleic Acids Res. 2018;46:3061-3074 pubmed publisher
|
| Belli M, Iwata N, Nakamura T, Iwase A, Stupack D, Shimasaki S. FOXL2C134W-Induced CYP19 Expression via Cooperation With SMAD3 in HGrC1 Cells. Endocrinology. 2018;159:1690-1703 pubmed publisher
|
| Li T, Wang L, Du Y, Xie S, Yang X, Lian F, et al. Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation. Nucleic Acids Res. 2018;46:3218-3231 pubmed publisher
|
| Shao G, Wang R, Sun A, Wei J, Peng K, Dai Q, et al. The E3 ubiquitin ligase NEDD4 mediates cell migration signaling of EGFR in lung cancer cells. Mol Cancer. 2018;17:24 pubmed publisher
|
| Deng H, Zeng J, Zhang T, Gong L, Zhang H, Cheung E, et al. Histone H3.3K27M Mobilizes Multiple Cancer/Testis (CT) Antigens in Pediatric Glioma. Mol Cancer Res. 2018;16:623-633 pubmed publisher
|
| Li L, Liu T, Li Y, Wu C, Luo K, Yin Y, et al. The deubiquitinase USP9X promotes tumor cell survival and confers chemoresistance through YAP1 stabilization. Oncogene. 2018;37:2422-2431 pubmed publisher
|
| Zhou Z, Wang L, Ge F, Gong P, Wang H, Wang F, et al. Pold3 is required for genomic stability and telomere integrity in embryonic stem cells and meiosis. Nucleic Acids Res. 2018;46:3468-3486 pubmed publisher
|
| Tsai K, Courtney D, Cullen B. Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication. PLoS Pathog. 2018;14:e1006919 pubmed publisher
|
| Wang X, Sun D, Tai J, Chen S, Yu M, Ren D, et al. TFAP2C promotes stemness and chemotherapeutic resistance in colorectal cancer via inactivating hippo signaling pathway. J Exp Clin Cancer Res. 2018;37:27 pubmed publisher
|
| Søreng K, Munson M, Lamb C, Bjørndal G, Pankiv S, Carlsson S, et al. SNX18 regulates ATG9A trafficking from recycling endosomes by recruiting Dynamin-2. EMBO Rep. 2018;19: pubmed publisher
|
| Lindquist D, Alsina F, Herdenberg C, Larsson C, Höppener J, Wang N, et al. LRIG1 negatively regulates RET mutants and is downregulated in thyroid cancer. Int J Oncol. 2018;52:1189-1197 pubmed publisher
|
| Feldman M, Levy D. Peptide inhibition of the SETD6 methyltransferase catalytic activity. Oncotarget. 2018;9:4875-4885 pubmed publisher
|
| Lavoie H, Sahmi M, Maisonneuve P, Marullo S, Thevakumaran N, Jin T, et al. MEK drives BRAF activation through allosteric control of KSR proteins. Nature. 2018;554:549-553 pubmed publisher
|
| Gao X, Albee L, Volkman B, Gaponenko V, Majetschak M. Asymmetrical ligand-induced cross-regulation of chemokine (C-X-C motif) receptor 4 by α1-adrenergic receptors at the heteromeric receptor complex. Sci Rep. 2018;8:2730 pubmed publisher
|
| Wang S, Hu B, Ding Z, Dang Y, Wu J, Li D, et al. ATF6 safeguards organelle homeostasis and cellular aging in human mesenchymal stem cells. Cell Discov. 2018;4:2 pubmed publisher
|
| Kawasaki N, Isogaya K, Dan S, Yamori T, Takano H, Yao R, et al. TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling. Cell Discov. 2018;4:1 pubmed publisher
|
| Flanagan K, Alspach E, Pazolli E, Parajuli S, Ren Q, Arthur L, et al. c-Myb and C/EBPβ regulate OPN and other senescence-associated secretory phenotype factors. Oncotarget. 2018;9:21-36 pubmed publisher
|
| Yang X, Hu Z, Fan S, Zhang Q, Zhong Y, Guo D, et al. Picornavirus 2A protease regulates stress granule formation to facilitate viral translation. PLoS Pathog. 2018;14:e1006901 pubmed publisher
|
| Mao L, Kitani A, Similuk M, Oler A, Albenberg L, Kelsen J, et al. Loss-of-function CARD8 mutation causes NLRP3 inflammasome activation and Crohn's disease. J Clin Invest. 2018;128:1793-1806 pubmed publisher
|
| Chennupati V, Veiga D, Maslowski K, Andina N, Tardivel A, Yu E, et al. Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation. J Clin Invest. 2018;128:1597-1614 pubmed publisher
|
| Yin J, Chen W, Chao E, Soriano S, Wang L, Wang W, et al. Otud7a Knockout Mice Recapitulate Many Neurological Features of 15q13.3 Microdeletion Syndrome. Am J Hum Genet. 2018;102:296-308 pubmed publisher
|
| Anderson E, McClelland S, Maksimova E, Strezoska Å, Basila M, Briner A, et al. Lactobacillus gasseri CRISPR-Cas9 characterization In Vitro reveals a flexible mode of protospacer-adjacent motif recognition. PLoS ONE. 2018;13:e0192181 pubmed publisher
|
| Hsieh W, Hsu T, Chang Y, Lai M. IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells. Nat Commun. 2018;9:463 pubmed publisher
|
| Albee L, Laporte H, Gao X, Eby J, Cheng Y, Nevins A, et al. Identification and functional characterization of arginine vasopressin receptor 1A : atypical chemokine receptor 3 heteromers in vascular smooth muscle. Open Biol. 2018;8: pubmed publisher
|
| Itoh S, Mizuno K, Aikawa M, Aikawa E. Dimerization of sortilin regulates its trafficking to extracellular vesicles. J Biol Chem. 2018;293:4532-4544 pubmed publisher
|
| Bulgari D, Jha A, Deitcher D, Levitan E. Myopic (HD-PTP, PTPN23) selectively regulates synaptic neuropeptide release. Proc Natl Acad Sci U S A. 2018;115:1617-1622 pubmed publisher
|
| Elsaeidi F, MacPherson P, Mills E, Jui J, Flannery J, Goldman D. Notch Suppression Collaborates with Ascl1 and Lin28 to Unleash a Regenerative Response in Fish Retina, But Not in Mice. J Neurosci. 2018;38:2246-2261 pubmed publisher
|
| O Brien L, Guo Q, Bahrami Samani E, Park J, Hasso S, Lee Y, et al. Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies. PLoS Genet. 2018;14:e1007181 pubmed publisher
|
| Alpsoy A, Dykhuizen E. Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes. J Biol Chem. 2018;293:3892-3903 pubmed publisher
|
| McIntyre W, Netzband R, Bonenfant G, Biegel J, Miller C, Fuchs G, et al. Positive-sense RNA viruses reveal the complexity and dynamics of the cellular and viral epitranscriptomes during infection. Nucleic Acids Res. 2018;46:5776-5791 pubmed publisher
|
| Park S, Persaud S, Ogokeh S, Meyers T, Townsend D, Wei L. CRABP1 protects the heart from isoproterenol-induced acute and chronic remodeling. J Endocrinol. 2018;236:151-165 pubmed publisher
|
| Konno H, Yamauchi S, Berglund A, Putney R, MULE J, Barber G. Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production. Oncogene. 2018;37:2037-2051 pubmed publisher
|
| Kong F, Sun T, Kong X, Xie D, Li Z, Xie K. Krüppel-like Factor 4 Suppresses Serine/Threonine Kinase 33 Activation and Metastasis of Gastric Cancer through Reversing Epithelial-Mesenchymal Transition. Clin Cancer Res. 2018;24:2440-2451 pubmed publisher
|
| Ulu A, Oh W, Zuo Y, Frost J. Stress-activated MAPKs and CRM1 regulate the subcellular localization of Net1A to control cell motility and invasion. J Cell Sci. 2018;131: pubmed publisher
|
| Higa M, Oka M, Fujihara Y, Masuda K, Yoneda Y, Kishimoto T. Regulation of inflammatory responses by dynamic subcellular localization of RNA-binding protein Arid5a. Proc Natl Acad Sci U S A. 2018;115:E1214-E1220 pubmed publisher
|
| Zhang C, Hoang N, Leng F, Saxena L, Lee L, Alejo S, et al. LSD1 demethylase and the methyl-binding protein PHF20L1 prevent SET7 methyltransferase-dependent proteolysis of the stem-cell protein SOX2. J Biol Chem. 2018;293:3663-3674 pubmed publisher
|
| León Ortiz A, Panier S, Sarek G, Vannier J, Patel H, Campbell P, et al. A Distinct Class of Genome Rearrangements Driven by Heterologous Recombination. Mol Cell. 2018;69:292-305.e6 pubmed publisher
|
| Mito M, Kadota M, Tanaka K, Furuta Y, Abe K, Iwasaki S, et al. Cell Type-Specific Survey of Epigenetic Modifications by Tandem Chromatin Immunoprecipitation Sequencing. Sci Rep. 2018;8:1143 pubmed publisher
|
| Xiang Q, Ju H, Li Q, Mei S, Chen D, Choi Y, et al. Human Herpesvirus 8 Interferon Regulatory Factors 1 and 3 Mediate Replication and Latency Activities via Interactions with USP7 Deubiquitinase. J Virol. 2018;92: pubmed publisher
|
| Zhou J, Chen J, Zhang X, Gao Z, Liu C, Zhang Y, et al. Porcine Mx1 Protein Inhibits Classical Swine Fever Virus Replication by Targeting Nonstructural Protein NS5B. J Virol. 2018;92: pubmed publisher
|
| Cao S, Zhou K, Zhang Z, Luger K, Straight A. Constitutive centromere-associated network contacts confer differential stability on CENP-A nucleosomes in vitro and in the cell. Mol Biol Cell. 2018;29:751-762 pubmed publisher
|
| Tanida Miyake E, Koike M, Uchiyama Y, Tanida I. Optimization of mNeonGreen for Homo sapiens increases its fluorescent intensity in mammalian cells. PLoS ONE. 2018;13:e0191108 pubmed publisher
|
| Xiao X, Fan Y, Li J, Zhang X, Lou X, Dou Y, et al. Guidance of super-enhancers in regulation of IL-9 induction and airway inflammation. J Exp Med. 2018;215:559-574 pubmed publisher
|
| Chen M, Wan L, Zhang J, Zhang J, Méndez L, Clohessy J, et al. Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism. Nat Commun. 2018;9:159 pubmed publisher
|
| Boettcher M, Tian R, Blau J, Markegard E, Wagner R, Wu D, et al. Dual gene activation and knockout screen reveals directional dependencies in genetic networks. Nat Biotechnol. 2018;36:170-178 pubmed publisher
|
| Forest E, Logeay R, Geminard C, Kantar D, Frayssinoux F, Heron Milhavet L, et al. The apical scaffold big bang binds to spectrins and regulates the growth of Drosophila melanogaster wing discs. J Cell Biol. 2018;217:1047-1062 pubmed publisher
|
| Panayiotou C, Lindqvist R, Kurhade C, Vonderstein K, Pasto J, Edlund K, et al. Viperin Restricts Zika Virus and Tick-Borne Encephalitis Virus Replication by Targeting NS3 for Proteasomal Degradation. J Virol. 2018;92: pubmed publisher
|
| Workman A, Zhu L, Keel B, Smith T, Jones C. The Wnt Signaling Pathway Is Differentially Expressed during the Bovine Herpesvirus 1 Latency-Reactivation Cycle: Evidence That Two Protein Kinases Associated with Neuronal Survival, Akt3 and BMPR2, Are Expressed at Higher Levels during Latency. J Virol. 2018;92: pubmed publisher
|
| Chen X, He Z, Fu M, Wang Y, Wu H, Li X, et al. The E3 Ubiquitin Ligase Siah-1 Suppresses Avian Reovirus Infection by Targeting p10 for Degradation. J Virol. 2018;92: pubmed publisher
|
| Ding D, Liu J, Midic U, Wu Y, Dong K, Melnick A, et al. TDRD5 binds piRNA precursors and selectively enhances pachytene piRNA processing in mice. Nat Commun. 2018;9:127 pubmed publisher
|
| Rengachari S, Groiss S, Devos J, Caron E, Grandvaux N, Panne D. Structural basis of STAT2 recognition by IRF9 reveals molecular insights into ISGF3 function. Proc Natl Acad Sci U S A. 2018;115:E601-E609 pubmed publisher
|
| Fletcher K, Ulferts R, Jacquin E, Veith T, Gammoh N, Arasteh J, et al. The WD40 domain of ATG16L1 is required for its non-canonical role in lipidation of LC3 at single membranes. EMBO J. 2018;37: pubmed publisher
|
| Wang C, Kang X, Zhou L, Chai Z, Wu Q, Huang R, et al. Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson's disease-like pathology. Nat Commun. 2018;9:81 pubmed publisher
|
| Siljee J, Wang Y, Bernard A, Ersoy B, Zhang S, Marley A, et al. Subcellular localization of MC4R with ADCY3 at neuronal primary cilia underlies a common pathway for genetic predisposition to obesity. Nat Genet. 2018;50:180-185 pubmed publisher
|
| Yan T, Ooi W, Qamra A, Cheung A, Ma D, Sundaram G, et al. HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis. Nat Commun. 2018;9:100 pubmed publisher
|
| Mita P, Wudzinska A, Sun X, Andrade J, Nayak S, Kahler D, et al. LINE-1 protein localization and functional dynamics during the cell cycle. elife. 2018;7: pubmed publisher
|
| Cheng W, Wang S, Mestre A, Fu C, Makarem A, Xian F, et al. C9ORF72 GGGGCC repeat-associated non-AUG translation is upregulated by stress through eIF2α phosphorylation. Nat Commun. 2018;9:51 pubmed publisher
|
| Campbell M, Watanabe T, Nakano K, Davis R, Lyu Y, Tepper C, et al. KSHV episomes reveal dynamic chromatin loop formation with domain-specific gene regulation. Nat Commun. 2018;9:49 pubmed publisher
|
| Quaile A, Stogios P, Egorova O, Evdokimova E, Valleau D, Nocek B, et al. The Legionella pneumophila effector Ceg4 is a phosphotyrosine phosphatase that attenuates activation of eukaryotic MAPK pathways. J Biol Chem. 2018;293:3307-3320 pubmed publisher
|
| Wilkie A, Sharma M, Pesola J, Ericsson M, Fernandez R, Coen D. A Role for Myosin Va in Human Cytomegalovirus Nuclear Egress. J Virol. 2018;92: pubmed publisher
|
| Kim H, McKnite A, Xie Y, Christian J. Fibronectin type III and intracellular domains of Toll-like receptor 4 interactor with leucine-rich repeats (Tril) are required for developmental signaling. Mol Biol Cell. 2018;29:523-531 pubmed publisher
|
| Zeng J, Liu W, Fan Y, He D, Li L. PrLZ increases prostate cancer docetaxel resistance by inhibiting LKB1/AMPK-mediated autophagy. Theranostics. 2018;8:109-123 pubmed publisher
|
| Ding D, Bergmaier P, Sachs P, Klangwart M, Rückert T, Bartels N, et al. The CUE1 domain of the SNF2-like chromatin remodeler SMARCAD1 mediates its association with KRAB-associated protein 1 (KAP1) and KAP1 target genes. J Biol Chem. 2018;293:2711-2724 pubmed publisher
|
| Schulte B, Selyutina A, Opp S, Herschhorn A, Sodroski J, Pizzato M, et al. Localization to detergent-resistant membranes and HIV-1 core entry inhibition correlate with HIV-1 restriction by SERINC5. Virology. 2018;515:52-65 pubmed publisher
|
| Zhao X, Sehgal M, Hou Z, Cheng J, Shu S, Wu S, et al. Identification of Residues Controlling Restriction versus Enhancing Activities of IFITM Proteins on Entry of Human Coronaviruses. J Virol. 2018;92: pubmed publisher
|
| Serratore N, Baker K, Macadlo L, Gress A, Powers B, Atallah N, et al. A Novel Sterol-Signaling Pathway Governs Azole Antifungal Drug Resistance and Hypoxic Gene Repression in Saccharomyces cerevisiae. Genetics. 2018;208:1037-1055 pubmed publisher
|
| Wu J, Xiang S, Zhang M, Fang B, Huang H, Kwon O, et al. Histone deacetylase 6 (HDAC6) deacetylates extracellular signal-regulated kinase 1 (ERK1) and thereby stimulates ERK1 activity. J Biol Chem. 2018;293:1976-1993 pubmed publisher
|
| Cesa L, Shao H, Srinivasan S, Tse E, Jain C, Zuiderweg E, et al. X-linked inhibitor of apoptosis protein (XIAP) is a client of heat shock protein 70 (Hsp70) and a biomarker of its inhibition. J Biol Chem. 2018;293:2370-2380 pubmed publisher
|
| Han B, Zhou B, Qu Y, Gao B, Xu Y, Chung S, et al. FOXC1-induced non-canonical WNT5A-MMP7 signaling regulates invasiveness in triple-negative breast cancer. Oncogene. 2018;37:1399-1408 pubmed publisher
|
| Kim J, Sturgill D, Sebastian R, Khurana S, Tran A, Edwards G, et al. Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions. Mol Cell. 2018;69:36-47.e7 pubmed publisher
|
| He Y, She H, Zhang T, Xu H, Cheng L, Yepes M, et al. p38 MAPK inhibits autophagy and promotes microglial inflammatory responses by phosphorylating ULK1. J Cell Biol. 2018;217:315-328 pubmed publisher
|
| Wagner J, Christensen D, Bhattacharya A, Dawidziak D, Roganowicz M, Wan Y, et al. General Model for Retroviral Capsid Pattern Recognition by TRIM5 Proteins. J Virol. 2018;92: pubmed publisher
|
| Shi S, Kelly B, Wang C, Klingler K, Chan A, Eckert G, et al. Human IGF-I propeptide A promotes articular chondrocyte biosynthesis and employs glycosylation-dependent heparin binding. Biochim Biophys Acta Gen Subj. 2018;1862:567-575 pubmed publisher
|
| Butler A, Owens D, Wang L, King M. A novel role for sox7 in Xenopus early primordial germ cell development: mining the PGC transcriptome. Development. 2018;145: pubmed publisher
|
| Baumann D, Dai M, Lu H, Gilmour D. GFZF, a Glutathione S-Transferase Protein Implicated in Cell Cycle Regulation and Hybrid Inviability, Is a Transcriptional Coactivator. Mol Cell Biol. 2018;38: pubmed publisher
|
| Wu X, Li L, Jiang H. Mitochondrial inner-membrane protease Yme1 degrades outer-membrane proteins Tom22 and Om45. J Cell Biol. 2018;217:139-149 pubmed publisher
|
| Jules J, Chen W, Feng X, Li Y. C/EBPα transcription factor is regulated by the RANK cytoplasmic 535IVVY538 motif and stimulates osteoclastogenesis more strongly than c-Fos. J Biol Chem. 2018;293:1480-1492 pubmed publisher
|
| Schweitzer C, Zhang F, Boyer A, Valdez K, Cam M, Liang T. N-Myc Downstream-Regulated Gene 1 Restricts Hepatitis C Virus Propagation by Regulating Lipid Droplet Biogenesis and Viral Assembly. J Virol. 2018;92: pubmed publisher
|
| Uechi H, Kuranaga E, Iriki T, Takano K, Hirayama S, Miura M, et al. Ubiquitin-Binding Protein CG5445 Suppresses Aggregation and Cytotoxicity of Amyotrophic Lateral Sclerosis-Linked TDP-43 in Drosophila. Mol Cell Biol. 2018;38: pubmed publisher
|
| Qian X, Li X, Tan L, Lee J, Xia Y, Cai Q, et al. Conversion of PRPS Hexamer to Monomer by AMPK-Mediated Phosphorylation Inhibits Nucleotide Synthesis in Response to Energy Stress. Cancer Discov. 2018;8:94-107 pubmed publisher
|
| Guan X, Zhang Y, Yu M, Ren C, Gao Y, Yun B, et al. Residues 28 to 39 of the Extracellular Loop 1 of Chicken Na+/H+ Exchanger Type I Mediate Cell Binding and Entry of Subgroup J Avian Leukosis Virus. J Virol. 2018;92: pubmed publisher
|
| Csizmadia T, Lorincz P, Hegedus K, Széplaki S, Low P, Juhasz G. Molecular mechanisms of developmentally programmed crinophagy in Drosophila. J Cell Biol. 2018;217:361-374 pubmed publisher
|
| Cho H, Hwang Y, Yoon J, Lee M, Lee H, Daar I. EphrinB1 promotes cancer cell migration and invasion through the interaction with RhoGDI1. Oncogene. 2018;37:861-872 pubmed publisher
|
| Vaites L, Paulo J, Huttlin E, Harper J. Systematic Analysis of Human Cells Lacking ATG8 Proteins Uncovers Roles for GABARAPs and the CCZ1/MON1 Regulator C18orf8/RMC1 in Macroautophagic and Selective Autophagic Flux. Mol Cell Biol. 2018;38: pubmed publisher
|
| Jules J, Li Y, Chen W. C/EBPα and PU.1 exhibit different responses to RANK signaling for osteoclastogenesis. Bone. 2018;107:104-114 pubmed publisher
|
| Jiao L, Zhang H, Li D, Yang K, Tang J, Li X, et al. Regulation of glycolytic metabolism by autophagy in liver cancer involves selective autophagic degradation of HK2 (hexokinase 2). Autophagy. 2018;14:671-684 pubmed publisher
|
| Zhang F, Virshup D, Cheong J. Oncogenic RAS-induced CK1α drives nuclear FOXO proteolysis. Oncogene. 2018;37:363-376 pubmed publisher
|
| Yoo J, Yang W, Lee J, Kim B, Broaddus R, Lim J, et al. MIG-6 negatively regulates STAT3 phosphorylation in uterine epithelial cells. Oncogene. 2018;37:255-262 pubmed publisher
|
| Periyasamy P, Liao K, Kook Y, Niu F, Callen S, Guo M, et al. Cocaine-Mediated Downregulation of miR-124 Activates Microglia by Targeting KLF4 and TLR4 Signaling. Mol Neurobiol. 2018;55:3196-3210 pubmed publisher
|
| Henser Brownhill T, Monserrat J, Scaffidi P. Generation of an arrayed CRISPR-Cas9 library targeting epigenetic regulators: from high-content screens to in vivo assays. Epigenetics. 2017;12:1065-1075 pubmed publisher
|
| Foster C, Gualdrini F, Treisman R. Mutual dependence of the MRTF-SRF and YAP-TEAD pathways in cancer-associated fibroblasts is indirect and mediated by cytoskeletal dynamics. Genes Dev. 2017;31:2361-2375 pubmed publisher
|
| Civiero L, Cogo S, Kiekens A, Morganti C, Tessari I, Lobbestael E, et al. PAK6 Phosphorylates 14-3-3? to Regulate Steady State Phosphorylation of LRRK2. Front Mol Neurosci. 2017;10:417 pubmed publisher
|
| Greenwood M, Greenwood M, Gillard B, Chitra Devi R, Murphy D. Regulation of cAMP Responsive Element Binding Protein 3-Like 1 (Creb3l1) Expression by Orphan Nuclear Receptor Nr4a1. Front Mol Neurosci. 2017;10:413 pubmed publisher
|
| Xu Q, Tu J, Dou C, Zhang J, Yang L, Liu X, et al. HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma. Mol Cancer. 2017;16:178 pubmed publisher
|
| Kaniskan H, Eram M, Zhao K, Szewczyk M, Yang X, Schmidt K, et al. Discovery of Potent and Selective Allosteric Inhibitors of Protein Arginine Methyltransferase 3 (PRMT3). J Med Chem. 2017;: pubmed publisher
|
| Nitulescu I, Meyer S, Wen Q, Crispino J, Lemieux M, Levine R, et al. Mediator Kinase Phosphorylation of STAT1 S727 Promotes Growth of Neoplasms With JAK-STAT Activation. EBioMedicine. 2017;26:112-125 pubmed publisher
|
| Robitaille A, Caron E, Zucchini N, Mukawera E, Adam D, Mariani M, et al. DUSP1 regulates apoptosis and cell migration, but not the JIP1-protected cytokine response, during Respiratory Syncytial Virus and Sendai Virus infection. Sci Rep. 2017;7:17388 pubmed publisher
|
| Green K, Glineburg M, Kearse M, Flores B, Linsalata A, Fedak S, et al. RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response. Nat Commun. 2017;8:2005 pubmed publisher
|
| Wong J, Wei R, Lyu P, Tong O, Zhang S, Wen Q, et al. Clinical and in vitro analysis of Osteopontin as a prognostic indicator and unveil its potential downstream targets in bladder cancer. Int J Biol Sci. 2017;13:1373-1386 pubmed publisher
|
| Amin Wetzel N, Saunders R, Kamphuis M, Rato C, Preissler S, Harding H, et al. A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response. Cell. 2017;171:1625-1637.e13 pubmed publisher
|
| Hsu W, Ma Y, Liu Y, Lee E. Smad4 SUMOylation is essential for memory formation through upregulation of the skeletal myopathy gene TPM2. BMC Biol. 2017;15:112 pubmed publisher
|
| Spohrer S, Groß R, Nalbach L, Schwind L, Stumpf H, Menger M, et al. Functional interplay between the transcription factors USF1 and PDX-1 and protein kinase CK2 in pancreatic β-cells. Sci Rep. 2017;7:16367 pubmed publisher
|
| Li G, Montgomery J, Eckert M, Chang J, Tienda S, Lengyel E, et al. An activity-dependent proximity ligation platform for spatially resolved quantification of active enzymes in single cells. Nat Commun. 2017;8:1775 pubmed publisher
|
| Bajikar S, Wang C, Borten M, Pereira E, Atkins K, Janes K. Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer. Dev Cell. 2017;43:418-435.e13 pubmed publisher
|
| Le Guerroué F, Eck F, Jung J, Starzetz T, Mittelbronn M, Kaulich M, et al. Autophagosomal Content Profiling Reveals an LC3C-Dependent Piecemeal Mitophagy Pathway. Mol Cell. 2017;68:786-796.e6 pubmed publisher
|
| Devaul N, Koloustroubis K, Wang R, Sperry A. A novel interaction between kinase activities in regulation of cilia formation. BMC Cell Biol. 2017;18:33 pubmed publisher
|
| Zhang H, Wang L, Wong E, Tsang S, Xu P, Lendahl U, et al. An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis. elife. 2017;6: pubmed publisher
|
| Yu Z, Song H, Jia M, Zhang J, Wang W, Li Q, et al. USP1-UAF1 deubiquitinase complex stabilizes TBK1 and enhances antiviral responses. J Exp Med. 2017;214:3553-3563 pubmed publisher
|
| Johnson T, Chereji R, Stavreva D, Morris S, Hager G, Clark D. Conventional and pioneer modes of glucocorticoid receptor interaction with enhancer chromatin in vivo. Nucleic Acids Res. 2017;: pubmed publisher
|
| Oh J, Chen S, Varshavsky A. A reference-based protein degradation assay without global translation inhibitors. J Biol Chem. 2017;292:21457-21465 pubmed publisher
|
| Monteverde T, Tait Mulder J, Hedley A, Knight J, Sansom O, Murphy D. Calcium signalling links MYC to NUAK1. Oncogene. 2017;: pubmed publisher
|
| Wu X, Shi T, He Y, Wang F, Sang R, Ding J, et al. Methylation of transcription factor YY2 regulates its transcriptional activity and cell proliferation. Cell Discov. 2017;3:17035 pubmed publisher
|
| Morgan M, Rickels R, Collings C, He X, Cao K, Herz H, et al. A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation. Genes Dev. 2017;31:2003-2014 pubmed publisher
|
| Samandi S, Roy A, Delcourt V, Lucier J, Gagnon J, Beaudoin M, et al. Deep transcriptome annotation enables the discovery and functional characterization of cryptic small proteins. elife. 2017;6: pubmed publisher
|
| Zhou X, Delucia M, Hao C, Hrecka K, Monnie C, Skowronski J, et al. HIV-1 Vpr protein directly loads helicase-like transcription factor (HLTF) onto the CRL4-DCAF1 E3 ubiquitin ligase. J Biol Chem. 2017;292:21117-21127 pubmed publisher
|
| Torregrosa Muñumer R, Forslund J, Goffart S, Pfeiffer A, Stojkovič G, Carvalho G, et al. PrimPol is required for replication reinitiation after mtDNA damage. Proc Natl Acad Sci U S A. 2017;114:11398-11403 pubmed publisher
|
| Chen F, Zhang C, Wu H, Ma Y, Luo X, Gong X, et al. The E3 ubiquitin ligase SCFFBXL14 complex stimulates neuronal differentiation by targeting the Notch signaling factor HES1 for proteolysis. J Biol Chem. 2017;292:20100-20112 pubmed publisher
|
| Jakka P, Namani S, Murugan S, Rai N, Radhakrishnan G. The Brucella effector protein TcpB induces degradation of inflammatory caspases and thereby subverts non-canonical inflammasome activation in macrophages. J Biol Chem. 2017;292:20613-20627 pubmed publisher
|
| Schmitzberger F, Richter M, Gordiyenko Y, Robinson C, Dadlez M, Westermann S. Molecular basis for inner kinetochore configuration through RWD domain-peptide interactions. EMBO J. 2017;36:3458-3482 pubmed publisher
|
| Park M, Phan H, Busch F, Hinckley S, Brackbill J, Wysocki V, et al. Human Argonaute3 has slicer activity. Nucleic Acids Res. 2017;45:11867-11877 pubmed publisher
|
| Wang J, Zhang D, Du J, Zhou C, Li Z, Liu X, et al. Tet1 facilitates hypoxia tolerance by stabilizing the HIF-? proteins independent of its methylcytosine dioxygenase activity. Nucleic Acids Res. 2017;45:12700-12714 pubmed publisher
|
| Poleshko A, Shah P, Gupta M, Babu A, Morley M, Manderfield L, et al. Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction. Cell. 2017;171:573-587.e14 pubmed publisher
|
| Palmer C, Bruckner R, Paulo J, Kazak L, Long J, Mina A, et al. Cdkal1, a type 2 diabetes susceptibility gene, regulates mitochondrial function in adipose tissue. Mol Metab. 2017;6:1212-1225 pubmed publisher
|
| Chi X, Britt E, Shows H, Hjelmaas A, Shetty S, Cushing E, et al. ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase. Mol Metab. 2017;6:1137-1149 pubmed publisher
|
| Yuan H, Deng R, Zhao X, Chen R, Hou G, Zhang H, et al. SUMO1 modification of KHSRP regulates tumorigenesis by preventing the TL-G-Rich miRNA biogenesis. Mol Cancer. 2017;16:157 pubmed publisher
|
| Tarallo R, Giurato G, Bruno G, Ravo M, Rizzo F, Salvati A, et al. The nuclear receptor ER? engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading. Genome Biol. 2017;18:189 pubmed publisher
|
| Copping N, Christian S, Ritter D, Islam M, Buscher N, Zolkowska D, et al. Neuronal overexpression of Ube3a isoform 2 causes behavioral impairments and neuroanatomical pathology relevant to 15q11.2-q13.3 duplication syndrome. Hum Mol Genet. 2017;26:3995-4010 pubmed publisher
|
| Pu J, Keren Kaplan T, Bonifacino J. A Ragulator-BORC interaction controls lysosome positioning in response to amino acid availability. J Cell Biol. 2017;216:4183-4197 pubmed publisher
|
| Kulcsár P, Tálas A, Huszár K, Ligeti Z, Tóth E, Weinhardt N, et al. Crossing enhanced and high fidelity SpCas9 nucleases to optimize specificity and cleavage. Genome Biol. 2017;18:190 pubmed publisher
|
| Tang Y, Lin Y, Ni H, Dong J, Yuan H, Zhang Y, et al. Inhibiting Histone Deacetylase 2 (HDAC2) Promotes Functional Recovery From Stroke. J Am Heart Assoc. 2017;6: pubmed publisher
|
| Sapir T, Levy T, Kozer N, Shin I, Zamor V, Haffner Krausz R, et al. Notch Activation by Shootin1 Opposing Activities on 2 Ubiquitin Ligases. Cereb Cortex. 2017;:1-14 pubmed publisher
|
| Watanabe M, Iwakawa H, Tadakuma H, Tomari Y. Biochemical and single-molecule analyses of the RNA silencing suppressing activity of CrPV-1A. Nucleic Acids Res. 2017;45:10837-10844 pubmed publisher
|
| Bailey J, Shen W, Liang X, Crooke S. Nucleic acid binding proteins affect the subcellular distribution of phosphorothioate antisense oligonucleotides. Nucleic Acids Res. 2017;45:10649-10671 pubmed publisher
|
| Jingushi K, Uemura M, Ohnishi N, Nakata W, Fujita K, Naito T, et al. Extracellular vesicles isolated from human renal cell carcinoma tissues disrupt vascular endothelial cell morphology via azurocidin. Int J Cancer. 2017;: pubmed publisher
|
| Kanai S, Edwards A, Rurik J, Osei Owusu P, Blumer K. Proteolytic degradation of regulator of G protein signaling 2 facilitates temporal regulation of Gq/11 signaling and vascular contraction. J Biol Chem. 2017;292:19266-19278 pubmed publisher
|
| O Geen H, Ren C, Nicolet C, Perez A, Halmai J, Le V, et al. dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression. Nucleic Acids Res. 2017;45:9901-9916 pubmed publisher
|
| Carleton J, Berrett K, Gertz J. Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor α-Bound Enhancers. Cell Syst. 2017;5:333-344.e5 pubmed publisher
|
| Schattauer S, Land B, Reichard K, Abraham A, Burgeno L, Kuhar J, et al. Peroxiredoxin 6 mediates Gαi protein-coupled receptor inactivation by cJun kinase. Nat Commun. 2017;8:743 pubmed publisher
|
| Arnoult N, Correia A, Ma J, Merlo A, Garcia Gomez S, Maric M, et al. Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN. Nature. 2017;549:548-552 pubmed publisher
|
| Basu R, Duan X, Taylor M, Martin E, Muralidhar S, Wang Y, et al. Heterophilic Type II Cadherins Are Required for High-Magnitude Synaptic Potentiation in the Hippocampus. Neuron. 2017;96:160-176.e8 pubmed publisher
|
| Gao J, Huang M, Lai J, Mao K, Sun P, Cao Z, et al. Kindlin supports platelet integrin αIIbβ3 activation by interacting with paxillin. J Cell Sci. 2017;130:3764-3775 pubmed publisher
|
| Iwahori S, Kalejta R. Phosphorylation of transcriptional regulators in the retinoblastoma protein pathway by UL97, the viral cyclin-dependent kinase encoded by human cytomegalovirus. Virology. 2017;512:95-103 pubmed publisher
|
| Zhou X, Geng L, Wang D, Yi H, Talmon G, Wang J. R-Spondin1/LGR5 Activates TGFβ Signaling and Suppresses Colon Cancer Metastasis. Cancer Res. 2017;77:6589-6602 pubmed publisher
|
| Ruiz Torres S, Benight N, Karns R, Lower E, Guan J, Waltz S. HGFL-mediated RON signaling supports breast cancer stem cell phenotypes via activation of non-canonical ?-catenin signaling. Oncotarget. 2017;8:58918-58933 pubmed publisher
|
| Jiménez Canino R, Lorenzo Díaz F, Odermatt A, Bailey M, Livingstone D, Jaisser F, et al. 11?-HSD2 SUMOylation Modulates Cortisol-Induced Mineralocorticoid Receptor Nuclear Translocation Independently of Effects on Transactivation. Endocrinology. 2017;158:4047-4063 pubmed publisher
|
| Lungu C, Pinter S, Broche J, Rathert P, Jeltsch A. Modular fluorescence complementation sensors for live cell detection of epigenetic signals at endogenous genomic sites. Nat Commun. 2017;8:649 pubmed publisher
|
| Shi G, Somlo D, Kim G, Prescianotto Baschong C, Sun S, Beuret N, et al. ER-associated degradation is required for vasopressin prohormone processing and systemic water homeostasis. J Clin Invest. 2017;127:3897-3912 pubmed publisher
|
| Diaz J, Morgan C, Minogue C, Hebert A, Coon J, Wells J. A Split-Abl Kinase for Direct Activation in Cells. Cell Chem Biol. 2017;24:1250-1258.e4 pubmed publisher
|
| Kozuka T, Chaya T, Tamalu F, Shimada M, Fujimaki Aoba K, Kuwahara R, et al. The TRPM1 Channel Is Required for Development of the Rod ON Bipolar Cell-AII Amacrine Cell Pathway in the Retinal Circuit. J Neurosci. 2017;37:9889-9900 pubmed publisher
|
| Mattijssen S, Arimbasseri A, Iben J, Gaidamakov S, Lee J, Hafner M, et al. LARP4 mRNA codon-tRNA match contributes to LARP4 activity for ribosomal protein mRNA poly(A) tail length protection. elife. 2017;6: pubmed publisher
|
| Gulbranson D, Davis E, Demmitt B, Ouyang Y, Ye Y, Yu H, et al. RABIF/MSS4 is a Rab-stabilizing holdase chaperone required for GLUT4 exocytosis. Proc Natl Acad Sci U S A. 2017;114:E8224-E8233 pubmed publisher
|
| Kwon H, Chen H, Mathis D, Benoist C. Different molecular complexes that mediate transcriptional induction and repression by FoxP3. Nat Immunol. 2017;18:1238-1248 pubmed publisher
|
| Caino M, Seo J, Wang Y, Rivadeneira D, Gabrilovich D, Kim E, et al. Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer. J Clin Invest. 2017;127:3755-3769 pubmed publisher
|
| Kedage V, Strittmatter B, Dausinas P, Hollenhorst P. Phosphorylation of the oncogenic transcription factor ERG in prostate cells dissociates polycomb repressive complex 2, allowing target gene activation. J Biol Chem. 2017;292:17225-17235 pubmed publisher
|
| Małecki J, Jakobsson M, Ho A, Moen A, Rustan A, Falnes P. Uncovering human METTL12 as a mitochondrial methyltransferase that modulates citrate synthase activity through metabolite-sensitive lysine methylation. J Biol Chem. 2017;292:17950-17962 pubmed publisher
|
| Kikuma K, Li X, Kim D, Sutter D, Dickman D. Extended Synaptotagmin Localizes to Presynaptic ER and Promotes Neurotransmission and Synaptic Growth in Drosophila. Genetics. 2017;207:993-1006 pubmed publisher
|
| Lee S, Nam T, Kim K, Kim J, Yoon W, Heo S, et al. Aggregation-prone GFAP mutation in Alexander disease validated using a zebrafish model. BMC Neurol. 2017;17:175 pubmed publisher
|
| Tsutsumi R, Harizanova J, Stockert R, Schröder K, Bastiaens P, Neel B. Assay to visualize specific protein oxidation reveals spatio-temporal regulation of SHP2. Nat Commun. 2017;8:466 pubmed publisher
|
| Bussiere L, Choudhury P, BELLAIRE B, Miller C. Characterization of a Replicating Mammalian Orthoreovirus with Tetracysteine-Tagged μNS for Live-Cell Visualization of Viral Factories. J Virol. 2017;91: pubmed publisher
|
| Cole C, Russler Germain D, Ketkar S, Verdoni A, Smith A, Bangert C, et al. Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies. J Clin Invest. 2017;127:3657-3674 pubmed publisher
|
| Edupuganti R, Geiger S, Lindeboom R, Shi H, Hsu P, Lu Z, et al. N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis. Nat Struct Mol Biol. 2017;24:870-878 pubmed publisher
|
| Zhang Z, Jones A, Wu W, Kim J, Kang Y, Bi X, et al. Role of remodeling and spacing factor 1 in histone H2A ubiquitination-mediated gene silencing. Proc Natl Acad Sci U S A. 2017;114:E7949-E7958 pubmed publisher
|
| Xiao B, Goh J, Xiao L, Xian H, Lim K, Liou Y. Reactive oxygen species trigger Parkin/PINK1 pathway-dependent mitophagy by inducing mitochondrial recruitment of Parkin. J Biol Chem. 2017;292:16697-16708 pubmed publisher
|
| Li Y, Sun H, Zhang C, Zhang H, Fan F, Everley R, et al. Identification of translationally controlled tumor protein in promotion of DNA homologous recombination repair in cancer cells by affinity proteomics. Oncogene. 2017;36:6839-6849 pubmed publisher
|
| Li J, Chen C, Li Y, Matye D, Wang Y, Ding W, et al. Inhibition of insulin/PI3K/AKT signaling decreases adipose Sortilin 1 in mice and 3T3-L1 adipocytes. Biochim Biophys Acta Mol Basis Dis. 2017;1863:2924-2933 pubmed publisher
|
| Samwer M, Schneider M, Hoefler R, Schmalhorst P, Jude J, Zuber J, et al. DNA Cross-Bridging Shapes a Single Nucleus from a Set of Mitotic Chromosomes. Cell. 2017;170:956-972.e23 pubmed publisher
|
| Willén K, Edgar J, Hasegawa T, Tanaka N, Futter C, Gouras G. A? accumulation causes MVB enlargement and is modelled by dominant negative VPS4A. Mol Neurodegener. 2017;12:61 pubmed publisher
|
| Anantharaman A, Gholamalamdari O, Khan A, Yoon J, Jantsch M, Hartner J, et al. RNA-editing enzymes ADAR1 and ADAR2 coordinately regulate the editing and expression of Ctn RNA. FEBS Lett. 2017;591:2890-2904 pubmed publisher
|
| Lee J, Jeon Y, Lee K, Lee H, Park J, Jang H, et al. RNF20 Suppresses Tumorigenesis by Inhibiting the SREBP1c-PTTG1 Axis in Kidney Cancer. Mol Cell Biol. 2017;37: pubmed publisher
|
| Lee I, Kim G, Bae J, Kim J, Rhee K, Hwang D. The DNA replication protein Cdc6 inhibits the microtubule-organizing activity of the centrosome. J Biol Chem. 2017;292:16267-16276 pubmed publisher
|
| Ramirez Martinez A, Cenik B, Bezprozvannaya S, Chen B, Bassel Duby R, Liu N, et al. KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination. elife. 2017;6: pubmed publisher
|
| Lopes A, Domingues P, Zell R, Hale B. Structure-Guided Functional Annotation of the Influenza A Virus NS1 Protein Reveals Dynamic Evolution of the p85β-Binding Site during Circulation in Humans. J Virol. 2017;91: pubmed publisher
|
| Lu F, Wiedmer A, Martin K, Wickramasinghe P, Kossenkov A, Lieberman P. Coordinate Regulation of TET2 and EBNA2 Controls the DNA Methylation State of Latent Epstein-Barr Virus. J Virol. 2017;91: pubmed publisher
|
| Li S, Mi L, Yu L, Yu Q, Liu T, Wang G, et al. Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis. Proc Natl Acad Sci U S A. 2017;114:E7111-E7120 pubmed publisher
|
| Dewe J, Fuller B, Lentini J, Kellner S, Fu D. TRMT1-Catalyzed tRNA Modifications Are Required for Redox Homeostasis To Ensure Proper Cellular Proliferation and Oxidative Stress Survival. Mol Cell Biol. 2017;37: pubmed publisher
|
| Seo H, Choi Y, Kim M, Kang K, Urano T, Lee D. The 19S proteasome is directly involved in the regulation of heterochromatin spreading in fission yeast. J Biol Chem. 2017;292:17144-17155 pubmed publisher
|
| Yao Z, Yaeger R, Rodrik Outmezguine V, Tao A, Torres N, Chang M, et al. Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS. Nature. 2017;548:234-238 pubmed publisher
|
| Tiller K, Li L, Kumar S, Julian M, Garde S, Tessier P. Arginine mutations in antibody complementarity-determining regions display context-dependent affinity/specificity trade-offs. J Biol Chem. 2017;292:16638-16652 pubmed publisher
|
| Sheng X, You Q, Zhu H, Chang Z, Li Q, Wang H, et al. Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK. PLoS Pathog. 2017;13:e1006534 pubmed publisher
|
| Sheng L, Hu X, Du Y, Zhang G, Huang H, Scheres B, et al. Non-canonical WOX11-mediated root branching contributes to plasticity in Arabidopsis root system architecture. Development. 2017;144:3126-3133 pubmed publisher
|
| Pelletier J, Kwong R, Park S, Le B, Baden R, Cagliari A, et al. LEC1 sequentially regulates the transcription of genes involved in diverse developmental processes during seed development. Proc Natl Acad Sci U S A. 2017;114:E6710-E6719 pubmed publisher
|
| Cooper J, Ou Y, McMillan E, Vaden R, Zaman A, Bodemann B, et al. TBK1 Provides Context-Selective Support of the Activated AKT/mTOR Pathway in Lung Cancer. Cancer Res. 2017;77:5077-5094 pubmed publisher
|
| Kang Y, Stroud D, Baker M, De Souza D, Frazier A, Liem M, et al. Sengers Syndrome-Associated Mitochondrial Acylglycerol Kinase Is a Subunit of the Human TIM22 Protein Import Complex. Mol Cell. 2017;67:457-470.e5 pubmed publisher
|
| Deakyne J, Malecka K, Messick T, Lieberman P. Structural and Functional Basis for an EBNA1 Hexameric Ring in Epstein-Barr Virus Episome Maintenance. J Virol. 2017;91: pubmed publisher
|
| Panday A, Gupta A, Srinivasa K, Xiao L, Smith M, Grove A. DNA damage regulates direct association of TOR kinase with the RNA polymerase II-transcribed HMO1 gene. Mol Biol Cell. 2017;28:2449-2459 pubmed publisher
|
| Senturk J, Bohlman S, Manfredi J. Mdm2 selectively suppresses DNA damage arising from inhibition of topoisomerase II independent of p53. Oncogene. 2017;36:6085-6096 pubmed publisher
|
| LeBlanc M, Lehmann R. Domain-specific control of germ cell polarity and migration by multifunction Tre1 GPCR. J Cell Biol. 2017;216:2945-2958 pubmed publisher
|
| Gadadhar S, Dadi H, Bodakuntla S, Schnitzler A, Bièche I, Rusconi F, et al. Tubulin glycylation controls primary cilia length. J Cell Biol. 2017;216:2701-2713 pubmed publisher
|
| Dahal G, Pradhan S, Bates E. Inwardly rectifying potassium channels influence Drosophila wing morphogenesis by regulating Dpp release. Development. 2017;144:2771-2783 pubmed publisher
|
| Jih G, Iglesias N, Currie M, Bhanu N, Paulo J, Gygi S, et al. Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription. Nature. 2017;547:463-467 pubmed publisher
|
| Orav E, Atanasova T, Shintyapina A, Kesaf S, Kokko M, Partanen J, et al. NETO1 Guides Development of Glutamatergic Connectivity in the Hippocampus by Regulating Axonal Kainate Receptors. Eneuro. 2017;4: pubmed publisher
|
| Paclíková P, Bernatik O, Radaszkiewicz T, Bryja V. The N-Terminal Part of the Dishevelled DEP Domain Is Required for Wnt/β-Catenin Signaling in Mammalian Cells. Mol Cell Biol. 2017;37: pubmed publisher
|
| Bleuyard J, Fournier M, Nakato R, Couturier A, Katou Y, Ralf C, et al. MRG15-mediated tethering of PALB2 to unperturbed chromatin protects active genes from genotoxic stress. Proc Natl Acad Sci U S A. 2017;114:7671-7676 pubmed publisher
|
| Li J, Wang C, Wu C, Cao T, Xu G, Meng Q, et al. PKA-mediated Gli2 and Gli3 phosphorylation is inhibited by Hedgehog signaling in cilia and reduced in Talpid3 mutant. Dev Biol. 2017;429:147-157 pubmed publisher
|
| Gopanenko A, Malygin A, Tupikin A, Laktionov P, Kabilov M, Karpova G. Human ribosomal protein eS1 is engaged in cellular events related to processing and functioning of U11 snRNA. Nucleic Acids Res. 2017;45:9121-9137 pubmed publisher
|
| Zhu Y, Vidaurre O, Adula K, Kezunovic N, Wentling M, Huntley G, et al. Subcellular Distribution of HDAC1 in Neurotoxic Conditions Is Dependent on Serine Phosphorylation. J Neurosci. 2017;37:7547-7559 pubmed publisher
|
| Li X, Yao B, Chen L, Kang Y, Li Y, Cheng Y, et al. Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis. Nat Commun. 2017;8:15903 pubmed publisher
|
| Wang Z, Deng X, Zou W, Engelhardt J, Yan Z, Qiu J. Human Bocavirus 1 Is a Novel Helper for Adeno-associated Virus Replication. J Virol. 2017;91: pubmed publisher
|
| Zhang H, Ye H, Liu S, Deng C, Li X, Shi P, et al. West Nile Virus NS1 Antagonizes Interferon Beta Production by Targeting RIG-I and MDA5. J Virol. 2017;91: pubmed publisher
|
| Aguado L, Schmid S, May J, Sabin L, Panis M, Blanco Melo D, et al. RNase III nucleases from diverse kingdoms serve as antiviral effectors. Nature. 2017;547:114-117 pubmed publisher
|
| Li X, Thome S, Ma X, Amrute Nayak M, Finigan A, Kitt L, et al. MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism. Nat Commun. 2017;8:15986 pubmed publisher
|
| Laviolette L, Mermoud J, Calvo I, Olson N, Boukhali M, Steinlein O, et al. Negative regulation of EGFR signalling by the human folliculin tumour suppressor protein. Nat Commun. 2017;8:15866 pubmed publisher
|
| Hsu J, Hubbell Engler B, Adelmant G, Huang J, Joyce C, Vazquez F, et al. PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of Cancer. Cancer Res. 2017;77:4613-4625 pubmed publisher
|
| Carlson S, Soulette C, Yang Z, Elias J, Brooks A, Gozani O. RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons and is itself regulated by lysine mono-methylation. J Biol Chem. 2017;292:13381-13390 pubmed publisher
|
| Jiang L, Xiong J, Zhan J, Yuan F, Tang M, Zhang C, et al. Ubiquitin-specific peptidase 7 (USP7)-mediated deubiquitination of the histone deacetylase SIRT7 regulates gluconeogenesis. J Biol Chem. 2017;292:13296-13311 pubmed publisher
|
| Zhu S, Ding S, Wang P, Wei Z, Pan W, Palm N, et al. Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells. Nature. 2017;546:667-670 pubmed publisher
|
| Nozawa R, Boteva L, Soares D, Naughton C, Dun A, Buckle A, et al. SAF-A Regulates Interphase Chromosome Structure through Oligomerization with Chromatin-Associated RNAs. Cell. 2017;169:1214-1227.e18 pubmed publisher
|
| Peng Y, Yuan J, Zhang Z, Chang X. Cytoplasmic poly(A)-binding protein 1 (PABPC1) interacts with the RNA-binding protein hnRNPLL and thereby regulates immunoglobulin secretion in plasma cells. J Biol Chem. 2017;292:12285-12295 pubmed publisher
|
| Rohira A, Yan F, Wang L, Wang J, Zhou S, Lu A, et al. Targeting SRC Coactivators Blocks the Tumor-Initiating Capacity of Cancer Stem-like Cells. Cancer Res. 2017;77:4293-4304 pubmed publisher
|
| Touma C, Adams M, Ashton N, Mizzi M, El Kamand S, Richard D, et al. A data-driven structural model of hSSB1 (NABP2/OBFC2B) self-oligomerization. Nucleic Acids Res. 2017;45:8609-8620 pubmed publisher
|
| Khin N, Lowe J, Jensen L, Burgio G. No evidence for genome editing in mouse zygotes and HEK293T human cell line using the DNA-guided Natronobacterium gregoryi Argonaute (NgAgo). PLoS ONE. 2017;12:e0178768 pubmed publisher
|
| DeCotiis J, Ortiz N, Vega B, Lukac D. An easily transfectable cell line that produces an infectious reporter virus for routine and robust quantitation of Kaposi's sarcoma-associated herpesvirus reactivation. J Virol Methods. 2017;247:99-106 pubmed publisher
|
| Lu X, Nowicka U, Sridharan V, Liu F, Randles L, Hymel D, et al. Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets. Nat Commun. 2017;8:15540 pubmed publisher
|
| Xu W, Luthra P, Wu C, Batra J, Leung D, Basler C, et al. Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis. Nat Commun. 2017;8:15576 pubmed publisher
|
| Han C, Zeng X, Yao S, Gao L, Zhang L, Qi X, et al. Voltage-Dependent Anion Channel 1 Interacts with Ribonucleoprotein Complexes To Enhance Infectious Bursal Disease Virus Polymerase Activity. J Virol. 2017;91: pubmed publisher
|
| Zou Z, Meng Z, Ma C, Liang D, Sun R, Lan K. Guanylate-Binding Protein 1 Inhibits Nuclear Delivery of Kaposi's Sarcoma-Associated Herpesvirus Virions by Disrupting Formation of Actin Filament. J Virol. 2017;91: pubmed publisher
|
| De Kumar B, Parker H, PARRISH M, Lange J, Slaughter B, Unruh J, et al. Dynamic regulation of Nanog and stem cell-signaling pathways by Hoxa1 during early neuro-ectodermal differentiation of ES cells. Proc Natl Acad Sci U S A. 2017;114:5838-5845 pubmed publisher
|
| Monis W, Faundez V, Pazour G. BLOC-1 is required for selective membrane protein trafficking from endosomes to primary cilia. J Cell Biol. 2017;216:2131-2150 pubmed publisher
|
| Feng J, Jing J, Li J, Zhao H, Punj V, Zhang T, et al. BMP signaling orchestrates a transcriptional network to control the fate of mesenchymal stem cells in mice. Development. 2017;144:2560-2569 pubmed publisher
|
| Tan S, Chadha S, Liu Y, Gabasova E, Perera D, Ahmed K, et al. A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability. Cell. 2017;169:1105-1118.e15 pubmed publisher
|
| Di Marco S, Hasanova Z, Kanagaraj R, Chappidi N, Altmannova V, Menon S, et al. RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis. Mol Cell. 2017;66:658-671.e8 pubmed publisher
|
| Ozdilek B, Thompson V, Ahmed N, White C, Batey R, Schwartz J. Intrinsically disordered RGG/RG domains mediate degenerate specificity in RNA binding. Nucleic Acids Res. 2017;45:7984-7996 pubmed publisher
|
| Liu Y, Du S, Ding M, Dou X, Zhang F, Wu Z, et al. The BMP4-Smad signaling pathway regulates hyperandrogenism development in a female mouse model. J Biol Chem. 2017;292:11740-11750 pubmed publisher
|
| Li Y, Luo K, Yin Y, Wu C, Deng M, Li L, et al. USP13 regulates the RAP80-BRCA1 complex dependent DNA damage response. Nat Commun. 2017;8:15752 pubmed publisher
|
| Wong M, Chen S. Hepatitis C Virus Subverts Human Choline Kinase-α To Bridge Phosphatidylinositol-4-Kinase IIIα (PI4KIIIα) and NS5A and Upregulates PI4KIIIα Activation, Thereby Promoting the Translocation of the Ternary Complex to the Endoplasmic Reticulum for Viral . J Virol. 2017;91: pubmed publisher
|
| Mompeán M, Romano V, Pantoja Uceda D, Stuani C, Baralle F, Buratti E, et al. Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions. J Biol Chem. 2017;292:11992-12006 pubmed publisher
|
| Cho J, Kim S, Seo Y, Park S, Park B, Kim J, et al. The p90 ribosomal S6 kinase-UBR5 pathway controls Toll-like receptor signaling via miRNA-induced translational inhibition of tumor necrosis factor receptor-associated factor 3. J Biol Chem. 2017;292:11804-11814 pubmed publisher
|
| Li Q, Kellner D, Hatch H, Yumita T, Sanchez S, Machold R, et al. Conserved properties of Drosophila Insomniac link sleep regulation and synaptic function. PLoS Genet. 2017;13:e1006815 pubmed publisher
|
| Bergen D, Stevenson N, Skinner R, Stephens D, Hammond C. The Golgi matrix protein giantin is required for normal cilia function in zebrafish. Biol Open. 2017;6:1180-1189 pubmed publisher
|
| Sakamaki J, Wilkinson S, Hahn M, Tasdemir N, O Prey J, Clark W, et al. Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function. Mol Cell. 2017;66:517-532.e9 pubmed publisher
|
| Sun J, Yu S, Zhang X, Capac C, Aligbe O, Daudelin T, et al. A Wntless-SEC12 complex on the ER membrane regulates early Wnt secretory vesicle assembly and mature ligand export. J Cell Sci. 2017;130:2159-2171 pubmed publisher
|
| Rozanska A, Richter Dennerlein R, Rorbach J, Gao F, Lewis R, Chrzanowska Lightowlers Z, et al. The human RNA-binding protein RBFA promotes the maturation of the mitochondrial ribosome. Biochem J. 2017;474:2145-2158 pubmed publisher
|
| Croft L, Ashton N, Paquet N, Bolderson E, O Byrne K, Richard D. hSSB1 associates with and promotes stability of the BLM helicase. BMC Mol Biol. 2017;18:13 pubmed publisher
|
| Xue P, Zeng F, Duan Q, Xiao J, Liu L, Yuan P, et al. BCKDK of BCAA Catabolism Cross-talking With the MAPK Pathway Promotes Tumorigenesis of Colorectal Cancer. EBioMedicine. 2017;20:50-60 pubmed publisher
|
| Wu R, Tam J, Collins K. DNA-binding determinants and cellular thresholds for human telomerase repeat addition processivity. EMBO J. 2017;36:1908-1927 pubmed publisher
|
| Liu K, Niu Y, Konishi M, Wu Y, Du H, Sun Chung H, et al. Discovery of nitrate-CPK-NLP signalling in central nutrient-growth networks. Nature. 2017;545:311-316 pubmed publisher
|
| Gan W, Zhang C, Siu K, Satoh A, Tanner J, Yu S. ULK1 phosphorylates Sec23A and mediates autophagy-induced inhibition of ER-to-Golgi traffic. BMC Cell Biol. 2017;18:22 pubmed publisher
|
| Imbert P, Louche A, Luizet J, Grandjean T, Bigot S, Wood T, et al. A Pseudomonas aeruginosa TIR effector mediates immune evasion by targeting UBAP1 and TLR adaptors. EMBO J. 2017;36:1869-1887 pubmed publisher
|
| Shibata T, Hadano J, Kawasaki D, Dong X, Kawabata S. Drosophila TG-A transglutaminase is secreted via an unconventional Golgi-independent mechanism involving exosomes and two types of fatty acylations. J Biol Chem. 2017;292:10723-10734 pubmed publisher
|
| Zhang Y, Reichel J, Han C, Zuniga Hertz J, Cai D. Astrocytic Process Plasticity and IKKβ/NF-κB in Central Control of Blood Glucose, Blood Pressure, and Body Weight. Cell Metab. 2017;25:1091-1102.e4 pubmed publisher
|
| Moleirinho S, Hoxha S, Mandati V, Curtale G, Troutman S, Ehmer U, et al. Regulation of localization and function of the transcriptional co-activator YAP by angiomotin. elife. 2017;6: pubmed publisher
|
| Ishii S, Torii M, Son A, Rajendraprasad M, Morozov Y, Kawasawa Y, et al. Variations in brain defects result from cellular mosaicism in the activation of heat shock signalling. Nat Commun. 2017;8:15157 pubmed publisher
|
| Fuller M, Majumder K, Pintel D. Minute Virus of Mice Inhibits Transcription of the Cyclin B1 Gene during Infection. J Virol. 2017;91: pubmed publisher
|
| Acharya D, Hainer S, Yoon Y, Wang F, Bach I, Rivera Pérez J, et al. KAT-Independent Gene Regulation by Tip60 Promotes ESC Self-Renewal but Not Pluripotency. Cell Rep. 2017;19:671-679 pubmed publisher
|
| Birot A, Eguienta K, Vazquez S, Claverol S, Bonneu M, Ekwall K, et al. A second Wpl1 anti-cohesion pathway requires dephosphorylation of fission yeast kleisin Rad21 by PP4. EMBO J. 2017;36:1364-1378 pubmed publisher
|
| Bradshaw N, Yerabham A, Marreiros R, Zhang T, Nagel Steger L, Korth C. An unpredicted aggregation-critical region of the actin-polymerizing protein TRIOBP-1/Tara, determined by elucidation of its domain structure. J Biol Chem. 2017;292:9583-9598 pubmed publisher
|
| Kaufman D, Papillon J, Larose L, Iwawaki T, Cybulsky A. Deletion of inositol-requiring enzyme-1? in podocytes disrupts glomerular capillary integrity and autophagy. Mol Biol Cell. 2017;28:1636-1651 pubmed publisher
|
| Blank M, Chen S, Poetz F, Schnolzer M, Voit R, Grummt I. SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription. Nucleic Acids Res. 2017;45:2675-2686 pubmed publisher
|
| Xu X, Kathare P, Pham V, Bu Q, Nguyen A, Huq E. Reciprocal proteasome-mediated degradation of PIFs and HFR1 underlies photomorphogenic development in Arabidopsis. Development. 2017;144:1831-1840 pubmed publisher
|
| Kissig M, Ishibashi J, Harms M, Lim H, Stine R, Won K, et al. PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing. EMBO J. 2017;36:1528-1542 pubmed publisher
|
| Wang X, Wang R, Luo M, Li C, Wang H, Huan C, et al. (DEAD)-box RNA helicase 3 modulates NF-κB signal pathway by controlling the phosphorylation of PP2A-C subunit. Oncotarget. 2017;8:33197-33213 pubmed publisher
|
| Tsai C, Wu Y, Pao P, Phillips C, Williams C, Miller C, et al. Proteolytic control of the mitochondrial calcium uniporter complex. Proc Natl Acad Sci U S A. 2017;114:4388-4393 pubmed publisher
|
| Taabazuing C, Okondo M, Bachovchin D. Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages. Cell Chem Biol. 2017;24:507-514.e4 pubmed publisher
|
| Bhujabal Z, Birgisdottir A, Sjøttem E, Brenne H, Øvervatn A, Habisov S, et al. FKBP8 recruits LC3A to mediate Parkin-independent mitophagy. EMBO Rep. 2017;18:947-961 pubmed publisher
|
| Salinas R, Pearring J, Ding J, Spencer W, Hao Y, Arshavsky V. Photoreceptor discs form through peripherin-dependent suppression of ciliary ectosome release. J Cell Biol. 2017;216:1489-1499 pubmed publisher
|
| Wang L, Zhang T, Wang L, Cai Y, Zhong X, He X, et al. Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission. EMBO J. 2017;36:1330-1347 pubmed publisher
|
| Lopez C, Singh S, Hambarde S, Griffin W, Gao J, Chib S, et al. Yeast Sub1 and human PC4 are G-quadruplex binding proteins that suppress genome instability at co-transcriptionally formed G4 DNA. Nucleic Acids Res. 2017;45:5850-5862 pubmed publisher
|
| Qi Q, Kang S, Zhang S, Pham C, Fu H, Brat D, et al. Co-amplification of phosphoinositide 3-kinase enhancer A and cyclin-dependent kinase 4 triggers glioblastoma progression. Oncogene. 2017;36:4562-4572 pubmed publisher
|
| Tesseur I, Nguyen A, Chang B, Li L, Woodling N, Wyss Coray T, et al. Deficiency in Neuronal TGF-β Signaling Leads to Nigrostriatal Degeneration and Activation of TGF-β Signaling Protects against MPTP Neurotoxicity in Mice. J Neurosci. 2017;37:4584-4592 pubmed publisher
|
| Kalyanaraman H, Zhuang S, Pilz R, Casteel D. The activity of cGMP-dependent protein kinase I? is not directly regulated by oxidation-induced disulfide formation at cysteine 43. J Biol Chem. 2017;292:8262-8268 pubmed publisher
|
| Salsman J, Rapkin L, Margam N, Duncan R, Bazett Jones D, Dellaire G. Myogenic differentiation triggers PML nuclear body loss and DAXX relocalization to chromocentres. Cell Death Dis. 2017;8:e2724 pubmed publisher
|
| Thomas D, Clare S, Sowerby J, Pardo M, Juss J, Goulding D, et al. Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity. J Exp Med. 2017;214:1111-1128 pubmed publisher
|
| Song Z, Xiaoli A, Zhang Q, Zhang Y, Yang E, Wang S, et al. Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein ?. J Biol Chem. 2017;292:8918-8932 pubmed publisher
|
| Eser U, Chandler Brown D, Ay F, Straight A, Duan Z, Noble W, et al. Form and function of topologically associating genomic domains in budding yeast. Proc Natl Acad Sci U S A. 2017;114:E3061-E3070 pubmed publisher
|
| Wang S, Cao Z, Xue J, Li H, Jiang W, Cheng Y, et al. A positive feedback loop between Pim-1 kinase and HBP1 transcription factor contributes to hydrogen peroxide-induced premature senescence and apoptosis. J Biol Chem. 2017;292:8207-8222 pubmed publisher
|
| Guedouari H, Daigle T, Scorrano L, Hébert Chatelain E. Sirtuin 5 protects mitochondria from fragmentation and degradation during starvation. Biochim Biophys Acta Mol Cell Res. 2017;1864:169-176 pubmed publisher
|
| Smirnov A, Wang C, Drewry L, Vogel J. Molecular mechanism of mRNA repression in trans by a ProQ-dependent small RNA. EMBO J. 2017;36:1029-1045 pubmed publisher
|
| Feng X, Hsu S, Kasbek C, Chaiken M, Price C. CTC1-mediated C-strand fill-in is an essential step in telomere length maintenance. Nucleic Acids Res. 2017;45:4281-4293 pubmed publisher
|
| Li L, Yu J, Zhang Y, Yang Q, Li Y, Zhang L, et al. Interferon-Inducible Oligoadenylate Synthetase-Like Protein Acts as an Antiviral Effector against Classical Swine Fever Virus via the MDA5-Mediated Type I Interferon-Signaling Pathway. J Virol. 2017;91: pubmed publisher
|
| Marwaha R, Arya S, Jagga D, Kaur H, Tuli A, Sharma M. The Rab7 effector PLEKHM1 binds Arl8b to promote cargo traffic to lysosomes. J Cell Biol. 2017;216:1051-1070 pubmed publisher
|
| Wang X, Cao W, Zhang J, Yan M, Xu Q, Wu X, et al. A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination. EMBO J. 2017;36:1243-1260 pubmed publisher
|
| Jendresen C, Arskog V, Daws M, Nilsson L. The Alzheimer's disease risk factors apolipoprotein E and TREM2 are linked in a receptor signaling pathway. J Neuroinflammation. 2017;14:59 pubmed publisher
|
| Zhang C, Jiang H, Wang P, Liu H, Sun X. Transcription factor NF-kappa B represses ANT1 transcription and leads to mitochondrial dysfunctions. Sci Rep. 2017;7:44708 pubmed publisher
|
| Schweisgut J, Schütt C, Wüst S, Wietelmann A, Ghesquière B, Carmeliet P, et al. Sex-specific, reciprocal regulation of ERα and miR-22 controls muscle lipid metabolism in male mice. EMBO J. 2017;36:1199-1214 pubmed publisher
|
| Malonis R, Fu W, Jelcic M, Thompson M, Canter B, Tsikitis M, et al. RNF11 sequestration of the E3 ligase SMURF2 on membranes antagonizes SMAD7 down-regulation of transforming growth factor β signaling. J Biol Chem. 2017;292:7435-7451 pubmed publisher
|
| Han R, Xu L, Wang T, Liu B, Wang L. A Small Regulatory RNA Contributes to the Preferential Colonization of Escherichia coli O157:H7 in the Large Intestine in Response to a Low DNA Concentration. Front Microbiol. 2017;8:274 pubmed publisher
|
| Yang X, Park S, Chang H, Shapiro J, Vassilopoulos A, Sawicki K, et al. Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2. J Clin Invest. 2017;127:1505-1516 pubmed publisher
|
| Shimelis H, Mesman R, von Nicolai C, Ehlén A, Guidugli L, Martin C, et al. BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer. Cancer Res. 2017;77:2789-2799 pubmed publisher
|
| Ke Y, Han Y, Guo X, Wen J, Wang K, Jiang X, et al. PARP1 promotes gene expression at the post-transcriptiona level by modulating the RNA-binding protein HuR. Nat Commun. 2017;8:14632 pubmed publisher
|
| Banerjee Mustafi S, Chakraborty P, Dwivedi S, Ding K, Moxley K, Mukherjee P, et al. BMI1, a new target of CK2?. Mol Cancer. 2017;16:56 pubmed publisher
|
| Egunsola A, Bae Y, Jiang M, Liu D, Chen Evenson Y, Bertin T, et al. Loss of DDRGK1 modulates SOX9 ubiquitination in spondyloepimetaphyseal dysplasia. J Clin Invest. 2017;127:1475-1484 pubmed publisher
|
| Egloff S, Vitali P, Tellier M, Raffel R, Murphy S, Kiss T. The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression. EMBO J. 2017;36:934-948 pubmed publisher
|
| Rakhimova A, Ura S, Hsu D, Wang H, Pears C, Lakin N. Site-specific ADP-ribosylation of histone H2B in response to DNA double strand breaks. Sci Rep. 2017;7:43750 pubmed publisher
|
| Garstkiewicz M, Strittmatter G, Grossi S, Sand J, Fenini G, Werner S, et al. Opposing effects of Nrf2 and Nrf2-activating compounds on the NLRP3 inflammasome independent of Nrf2-mediated gene expression. Eur J Immunol. 2017;47:806-817 pubmed publisher
|
| Leung J, Makharashvili N, Agarwal P, Chiu L, Pourpre R, Cammarata M, et al. ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair. Genes Dev. 2017;31:260-274 pubmed publisher
|
| Liu H, Wang K, Chen S, Sun Q, Zhang Y, Chen L, et al. NFATc1 phosphorylation by DYRK1A increases its protein stability. PLoS ONE. 2017;12:e0172985 pubmed publisher
|
| Vega Cabrera L, Guerrero A, Rodríguez Mejía J, Tabche M, Wood C, Gutiérrez Ríos R, et al. Analysis of Spo0M function in Bacillus subtilis. PLoS ONE. 2017;12:e0172737 pubmed publisher
|
| Frémont S, Hammich H, Bai J, Wioland H, Klinkert K, Rocancourt M, et al. Oxidation of F-actin controls the terminal steps of cytokinesis. Nat Commun. 2017;8:14528 pubmed publisher
|
| Lin Y, Zhen Y, Chien K, Lee I, Lin W, Chen M, et al. LIMCH1 regulates nonmuscle myosin-II activity and suppresses cell migration. Mol Biol Cell. 2017;28:1054-1065 pubmed publisher
|
| Liu Y, Cussiol J, Dibitetto D, Sims J, Twayana S, Weiss R, et al. TOPBP1Dpb11 plays a conserved role in homologous recombination DNA repair through the coordinated recruitment of 53BP1Rad9. J Cell Biol. 2017;216:623-639 pubmed publisher
|
| Möckel M, Heim A, Tischer T, Mayer T. Xenopus laevis Kif18A is a highly processive kinesin required for meiotic spindle integrity. Biol Open. 2017;6:463-470 pubmed publisher
|
| Liu Y, Sepich D, Solnica Krezel L. Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation. PLoS Genet. 2017;13:e1006564 pubmed publisher
|
| Lee J, Choi E, Seo H, Kang K, Gilmore J, Florens L, et al. Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation. Nat Commun. 2017;8:14527 pubmed publisher
|
| Karras G, Yi S, Sahni N, Fischer M, Xie J, Vidal M, et al. HSP90 Shapes the Consequences of Human Genetic Variation. Cell. 2017;168:856-866.e12 pubmed publisher
|
| Zhai L, Wang C, Chen Y, Zhou S, Li L. Rbm46 regulates mouse embryonic stem cell differentiation by targeting β-Catenin mRNA for degradation. PLoS ONE. 2017;12:e0172420 pubmed publisher
|
| Klett E, Chen S, Yechoor A, Lih F, Coleman R. Long-chain acyl-CoA synthetase isoforms differ in preferences for eicosanoid species and long-chain fatty acids. J Lipid Res. 2017;58:884-894 pubmed publisher
|
| Wang H, Guo H, Su J, Rui Y, Zheng W, Gao W, et al. Inhibition of Vpx-Mediated SAMHD1 and Vpr-Mediated Host Helicase Transcription Factor Degradation by Selective Disruption of Viral CRL4 (DCAF1) E3 Ubiquitin Ligase Assembly. J Virol. 2017;91: pubmed publisher
|
| Maskey R, Flatten K, Sieben C, Peterson K, Baker D, Nam H, et al. Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesis. Nucleic Acids Res. 2017;45:4564-4576 pubmed publisher
|
| Peng M, Yin N, Li M. SZT2 dictates GATOR control of mTORC1 signalling. Nature. 2017;543:433-437 pubmed publisher
|
| Xiong L, Jung J, Guo H, Pan J, Sun X, Mei L, et al. Osteoblastic Lrp4 promotes osteoclastogenesis by regulating ATP release and adenosine-A2AR signaling. J Cell Biol. 2017;216:761-778 pubmed publisher
|
| Zoltowska K, Maesako M, Lushnikova I, Takeda S, Keller L, Skibo G, et al. Dynamic presenilin 1 and synaptotagmin 1 interaction modulates exocytosis and amyloid β production. Mol Neurodegener. 2017;12:15 pubmed publisher
|
| Wang J, Rajbhandari P, Damianov A, Han A, Sallam T, Waki H, et al. RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs. J Clin Invest. 2017;127:987-1004 pubmed publisher
|
| Fischl H, Howe F, Furger A, Mellor J. Paf1 Has Distinct Roles in Transcription Elongation and Differential Transcript Fate. Mol Cell. 2017;65:685-698.e8 pubmed publisher
|
| Andralojc K, Campbell A, Kelly A, Terrey M, Tanner P, Gans I, et al. ELLI-1, a novel germline protein, modulates RNAi activity and P-granule accumulation in Caenorhabditis elegans. PLoS Genet. 2017;13:e1006611 pubmed publisher
|
| Tu Y, Liu H, Zhu X, Shen H, Ma X, Wang F, et al. Ataxin-3 promotes genome integrity by stabilizing Chk1. Nucleic Acids Res. 2017;45:4532-4549 pubmed publisher
|
| Xu J, Camacho M, Xu Y, Esser V, Liu X, Trimbuch T, et al. Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN. elife. 2017;6: pubmed publisher
|
| Hu Y, Lao L, Mao J, Jin W, Luo H, Charpentier T, et al. Armc5 deletion causes developmental defects and compromises T-cell immune responses. Nat Commun. 2017;8:13834 pubmed publisher
|
| Andrade E, Musante V, Horiuchi A, Matsuzaki H, Brody A, Wu T, et al. ARPP-16 Is a Striatal-Enriched Inhibitor of Protein Phosphatase 2A Regulated by Microtubule-Associated Serine/Threonine Kinase 3 (Mast 3 Kinase). J Neurosci. 2017;37:2709-2722 pubmed publisher
|
| Qiu X, Pascal L, Song Q, Zang Y, Ai J, O Malley K, et al. Physical and Functional Interactions between ELL2 and RB in the Suppression of Prostate Cancer Cell Proliferation, Migration, and Invasion. Neoplasia. 2017;19:207-215 pubmed publisher
|
| Palmieri M, Pal R, Nelvagal H, Lotfi P, Stinnett G, Seymour M, et al. mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases. Nat Commun. 2017;8:14338 pubmed publisher
|
| Kim D, Choi J, Fan C, Shearer R, Sharif M, Busch P, et al. Homo-trimerization is essential for the transcription factor function of Myrf for oligodendrocyte differentiation. Nucleic Acids Res. 2017;45:5112-5125 pubmed publisher
|
| Badgandi H, Hwang S, Shimada I, Loriot E, Mukhopadhyay S. Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins. J Cell Biol. 2017;216:743-760 pubmed publisher
|
| Hu Y, O Boyle K, Auer J, Raju S, You F, Wang P, et al. Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFκΒ signaling by stabilizing IκBα. PLoS Pathog. 2017;13:e1006187 pubmed publisher
|
| Brügger V, Duman M, Bochud M, Münger E, Heller M, Ruff S, et al. Delaying histone deacetylase response to injury accelerates conversion into repair Schwann cells and nerve regeneration. Nat Commun. 2017;8:14272 pubmed publisher
|
| Schou K, Mogensen J, Morthorst S, Nielsen B, Aleliunaite A, Serra Marques A, et al. KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling. Nat Commun. 2017;8:14177 pubmed publisher
|
| Qi S, Li Z, Schulze Gahmen U, Stjepanovic G, Zhou Q, Hurley J. Structural basis for ELL2 and AFF4 activation of HIV-1 proviral transcription. Nat Commun. 2017;8:14076 pubmed publisher
|
| Chen J, Xu W, Chen Y, Xie X, Zhang Y, Ma C, et al. Matrix Metalloproteinase 9 Facilitates Hepatitis B Virus Replication through Binding with Type I Interferon (IFN) Receptor 1 To Repress IFN/JAK/STAT Signaling. J Virol. 2017;91: pubmed publisher
|
| Mizunoe Y, Sudo Y, Okita N, Hiraoka H, Mikami K, Narahara T, et al. Involvement of lysosomal dysfunction in autophagosome accumulation and early pathologies in adipose tissue of obese mice. Autophagy. 2017;13:642-653 pubmed publisher
|
| Golden R, Chen B, Li T, Braun J, Manjunath H, Chen X, et al. An Argonaute phosphorylation cycle promotes microRNA-mediated silencing. Nature. 2017;542:197-202 pubmed publisher
|
| Liu C, Zhai X, Zhao B, Wang Y, Xu Z. Cyclin I-like (CCNI2) is a cyclin-dependent kinase 5 (CDK5) activator and is involved in cell cycle regulation. Sci Rep. 2017;7:40979 pubmed publisher
|
| Malecki J, Aileni V, Ho A, Schwarz J, Moen A, Sørensen V, et al. The novel lysine specific methyltransferase METTL21B affects mRNA translation through inducible and dynamic methylation of Lys-165 in human eukaryotic elongation factor 1 alpha (eEF1A). Nucleic Acids Res. 2017;45:4370-4389 pubmed publisher
|
| Jerković I, Ibrahim D, Andrey G, Haas S, Hansen P, Janetzki C, et al. Genome-Wide Binding of Posterior HOXA/D Transcription Factors Reveals Subgrouping and Association with CTCF. PLoS Genet. 2017;13:e1006567 pubmed publisher
|
| Quigley I, Kintner C. Rfx2 Stabilizes Foxj1 Binding at Chromatin Loops to Enable Multiciliated Cell Gene Expression. PLoS Genet. 2017;13:e1006538 pubmed publisher
|
| Jobe E, Gao Y, Eisinger B, Mladucky J, Giuliani C, Kelnhofer L, et al. Methyl-CpG-Binding Protein MBD1 Regulates Neuronal Lineage Commitment through Maintaining Adult Neural Stem Cell Identity. J Neurosci. 2017;37:523-536 pubmed publisher
|
| Wang Y, Pan Q, Ding S, Wang Z, Yu J, Finzi A, et al. The V3 Loop of HIV-1 Env Determines Viral Susceptibility to IFITM3 Impairment of Viral Infectivity. J Virol. 2017;91: pubmed publisher
|
| Inoue D, Stemmer M, Thumberger T, Ruppert T, Bärenz F, Wittbrodt J, et al. Expression of the novel maternal centrosome assembly factor Wdr8 is required for vertebrate embryonic mitoses. Nat Commun. 2017;8:14090 pubmed publisher
|
| Jun M, Ryu H, Jun Y, Liu T, Li Y, Lim C, et al. Sequestration of PRMT1 and Nd1-L mRNA into ALS-linked FUS mutant R521C-positive aggregates contributes to neurite degeneration upon oxidative stress. Sci Rep. 2017;7:40474 pubmed publisher
|
| Xu J, Zhou W, Yang F, Chen G, Li H, Zhao Y, et al. The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor. Nat Commun. 2017;8:14002 pubmed publisher
|
| Nakajima S, Aikawa C, Nozawa T, Minowa Nozawa A, Toh H, Nakagawa I. Bcl-xL Affects Group A Streptococcus-Induced Autophagy Directly, by Inhibiting Fusion between Autophagosomes and Lysosomes, and Indirectly, by Inhibiting Bacterial Internalization via Interaction with Beclin 1-UVRAG. PLoS ONE. 2017;12:e0170138 pubmed publisher
|
| Zaganelli S, Rebelo Guiomar P, Maundrell K, Rozanska A, Pierredon S, Powell C, et al. The Pseudouridine Synthase RPUSD4 Is an Essential Component of Mitochondrial RNA Granules. J Biol Chem. 2017;292:4519-4532 pubmed publisher
|
| Diamanti M, Gupta J, Bennecke M, De Oliveira T, Ramakrishnan M, Braczynski A, et al. IKK? controls ATG16L1 degradation to prevent ER stress during inflammation. J Exp Med. 2017;214:423-437 pubmed publisher
|
| Skene P, Henikoff S. An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites. elife. 2017;6: pubmed publisher
|
| Hiraga S, Ly T, Garzón J, Horejsi Z, Ohkubo Y, Endo A, et al. Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation. EMBO Rep. 2017;18:403-419 pubmed publisher
|
| Zhuang X, Chung K, Cui Y, Lin W, Gao C, Kang B, et al. ATG9 regulates autophagosome progression from the endoplasmic reticulum in Arabidopsis. Proc Natl Acad Sci U S A. 2017;114:E426-E435 pubmed publisher
|
| Anantharaman A, Tripathi V, Khan A, Yoon J, Singh D, Gholamalamdari O, et al. ADAR2 regulates RNA stability by modifying access of decay-promoting RNA-binding proteins. Nucleic Acids Res. 2017;45:4189-4201 pubmed publisher
|
| Lang X, Tang T, Jin T, Ding C, Zhou R, Jiang W. TRIM65-catalized ubiquitination is essential for MDA5-mediated antiviral innate immunity. J Exp Med. 2017;214:459-473 pubmed publisher
|
| Campos León K, Wijendra K, Siddiqa A, Pentland I, Feeney K, Knapman A, et al. Association of Human Papillomavirus 16 E2 with Rad50-Interacting Protein 1 Enhances Viral DNA Replication. J Virol. 2017;91: pubmed publisher
|
| Zhao Q, Cai W, Zhang X, Tian S, Zhang J, Li H, et al. RYBP Expression Is Regulated by KLF4 and Sp1 and Is Related to Hepatocellular Carcinoma Prognosis. J Biol Chem. 2017;292:2143-2158 pubmed publisher
|
| Yoon W, Sandoval H, Nagarkar Jaiswal S, Jaiswal M, Yamamoto S, Haelterman N, et al. Loss of Nardilysin, a Mitochondrial Co-chaperone for ?-Ketoglutarate Dehydrogenase, Promotes mTORC1 Activation and Neurodegeneration. Neuron. 2017;93:115-131 pubmed publisher
|
| Zhou C, Ma K, Gao R, Mu C, Chen L, Liu Q, et al. Regulation of mATG9 trafficking by Src- and ULK1-mediated phosphorylation in basal and starvation-induced autophagy. Cell Res. 2017;27:184-201 pubmed publisher
|
| Naeem A, Tommasi C, Cole C, Brown S, Zhu Y, Way B, et al. A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic d. J Allergy Clin Immunol. 2017;139:1228-1241 pubmed publisher
|
| Konieczny P, Stepniak Konieczna E, Taylor K, Sznajder L, Sobczak K. Autoregulation of MBNL1 function by exon 1 exclusion from MBNL1 transcript. Nucleic Acids Res. 2017;45:1760-1775 pubmed publisher
|
| Xu M, He J, Li J, Feng W, Zhou H, Wei H, et al. Methyl-CpG-binding domain 3 inhibits epithelial-mesenchymal transition in pancreatic cancer cells via TGF-β/Smad signalling. Br J Cancer. 2017;116:91-99 pubmed publisher
|
| Hashimoto K, Tsuji Y. Arsenic-Induced Activation of the Homeodomain-Interacting Protein Kinase 2 (HIPK2) to cAMP-Response Element Binding Protein (CREB) Axis. J Mol Biol. 2017;429:64-78 pubmed publisher
|
| Hao S, Zhang J, Chen Z, Xu H, Wang H, Guan W. Alternative Polyadenylation of Human Bocavirus at Its 3' End Is Regulated by Multiple Elements and Affects Capsid Expression. J Virol. 2017;91: pubmed publisher
|
| Jiang H, Zhang C, Tang Y, Zhao J, Wang T, Liu H, et al. The regulator of calcineurin 1 increases adenine nucleotide translocator 1 and leads to mitochondrial dysfunctions. J Neurochem. 2017;140:307-319 pubmed publisher
|
| Callegari S, Oeljeklaus S, Warscheid B, Dennerlein S, Thumm M, Rehling P, et al. Phospho-ubiquitin-PARK2 complex as a marker for mitophagy defects. Autophagy. 2017;13:201-211 pubmed publisher
|
| Choi Y, Shembade N, Parvatiyar K, Balachandran S, Harhaj E. TAX1BP1 Restrains Virus-Induced Apoptosis by Facilitating Itch-Mediated Degradation of the Mitochondrial Adaptor MAVS. Mol Cell Biol. 2017;37: pubmed publisher
|
| Matsuura K, Huang N, Cocce K, Zhang L, Kornbluth S. Downregulation of the proapoptotic protein MOAP-1 by the UBR5 ubiquitin ligase and its role in ovarian cancer resistance to cisplatin. Oncogene. 2017;36:1698-1706 pubmed publisher
|
| Uo T, Dvinge H, Sprenger C, Bradley R, Nelson P, Plymate S. Systematic and functional characterization of novel androgen receptor variants arising from alternative splicing in the ligand-binding domain. Oncogene. 2017;36:1440-1450 pubmed publisher
|
| Patel S, Trivedi G, Darie C, Clarkson B. The possible roles of B-cell novel protein-1 (BCNP1) in cellular signalling pathways and in cancer. J Cell Mol Med. 2017;21:456-466 pubmed publisher
|
| Yang Y, La H, Tang K, Miki D, Yang L, Wang B, et al. SAC3B, a central component of the mRNA export complex TREX-2, is required for prevention of epigenetic gene silencing in Arabidopsis. Nucleic Acids Res. 2017;45:181-197 pubmed publisher
|
| He Y, Chen Y, Song W, Zhu L, Dong Z, Ow D. A Pap1-Oxs1 signaling pathway for disulfide stress in Schizosaccharomyces pombe. Nucleic Acids Res. 2017;45:106-114 pubmed publisher
|
| Liu Z, Lam N, Wang E, Virden R, Pawel B, Attiyeh E, et al. Identification of CASZ1 NES reveals potential mechanisms for loss of CASZ1 tumor suppressor activity in neuroblastoma. Oncogene. 2017;36:97-109 pubmed publisher
|
| Koukouli F, Rooy M, Maskos U. Early and progressive deficit of neuronal activity patterns in a model of local amyloid pathology in mouse prefrontal cortex. Aging (Albany NY). 2016;8:3430-3449 pubmed publisher
|
| Urbanus M, Quaile A, Stogios P, Morar M, Rao C, Di Leo R, et al. Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila. Mol Syst Biol. 2016;12:893 pubmed publisher
|
| Bostaille N, Gauquier A, Twyffels L, Vanhollebeke B. Molecular insights into Adgra2/Gpr124 and Reck intracellular trafficking. Biol Open. 2016;5:1874-1881 pubmed publisher
|
| Fletcher C, Godfrey J, Shibakawa A, Bushell M, Bevan C. A novel role for GSK3? as a modulator of Drosha microprocessor activity and MicroRNA biogenesis. Nucleic Acids Res. 2016;: pubmed
|
| Shibata E, Kiran M, Shibata Y, Singh S, Kiran S, Dutta A. Two subunits of human ORC are dispensable for DNA replication and proliferation. elife. 2016;5: pubmed publisher
|
| Okashita N, Suwa Y, Nishimura O, Sakashita N, Kadota M, Nagamatsu G, et al. PRDM14 Drives OCT3/4 Recruitment via Active Demethylation in the Transition from Primed to Naive Pluripotency. Stem Cell Reports. 2016;7:1072-1086 pubmed publisher
|
| Schiffmacher A, Xie V, Taneyhill L. Cadherin-6B proteolysis promotes the neural crest cell epithelial-to-mesenchymal transition through transcriptional regulation. J Cell Biol. 2016;215:735-747 pubmed
|
| Bisht K, Smith E, Tesmer V, Nandakumar J. Structural and functional consequences of a disease mutation in the telomere protein TPP1. Proc Natl Acad Sci U S A. 2016;113:13021-13026 pubmed
|
| Yap C, Digilio L, McMahon L, Roszkowska M, Bott C, Kruczek K, et al. Different Doublecortin (DCX) Patient Alleles Show Distinct Phenotypes in Cultured Neurons: EVIDENCE FOR DIVERGENT LOSS-OF-FUNCTION AND "OFF-PATHWAY" CELLULAR MECHANISMS. J Biol Chem. 2016;291:26613-26626 pubmed publisher
|
| Guiney E, Klecker T, Emr S. Identification of the endocytic sorting signal recognized by the Art1-Rsp5 ubiquitin ligase complex. Mol Biol Cell. 2016;27:4043-4054 pubmed
|
| Gómez H L, Felipe Medina N, Sanchez Martin M, Davies O, Ramos I, García Tuñón I, et al. C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility. Nat Commun. 2016;7:13298 pubmed publisher
|
| Jaber N, Mohd Naim N, Wang Z, Deleon J, Kim S, Zhong H, et al. Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase-activating protein Armus. J Cell Sci. 2016;129:4424-4435 pubmed
|
| Kedage V, Selvaraj N, Nicholas T, Budka J, Plotnik J, Jerde T, et al. An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer. Cell Rep. 2016;17:1289-1301 pubmed publisher
|
| Lamason R, Bastounis E, Kafai N, Serrano R, Del Alamo J, Theriot J, et al. Rickettsia Sca4 Reduces Vinculin-Mediated Intercellular Tension to Promote Spread. Cell. 2016;167:670-683.e10 pubmed publisher
|
| Klein B, Wang X, Cui G, Yuan C, Botuyan M, Lin K, et al. PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation. Cell Rep. 2016;17:1158-1170 pubmed publisher
|
| Lorenzen I, Lokau J, Korpys Y, Oldefest M, Flynn C, Künzel U, et al. Control of ADAM17 activity by regulation of its cellular localisation. Sci Rep. 2016;6:35067 pubmed publisher
|
| Uematsu K, Okumura F, Tonogai S, Joo Okumura A, Alemayehu D, Nishikimi A, et al. ASB7 regulates spindle dynamics and genome integrity by targeting DDA3 for proteasomal degradation. J Cell Biol. 2016;215:95-106 pubmed
|
| Yoh K, Regunath K, Guzman A, Lee S, Pfister N, Akanni O, et al. Repression of p63 and induction of EMT by mutant Ras in mammary epithelial cells. Proc Natl Acad Sci U S A. 2016;113:E6107-E6116 pubmed
|
| Catena V, Bruno T, De Nicola F, Goeman F, Pallocca M, Iezzi S, et al. Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells. Oncotarget. 2016;7:70546-70558 pubmed publisher
|
| Hasegawa J, Sue M, Yamato M, Ichikawa J, Ishida S, Shibutani T, et al. Novel anti-EPHA2 antibody, DS-8895a for cancer treatment. Cancer Biol Ther. 2016;17:1158-1167 pubmed
|
| Vernia S, Edwards Y, Han M, Cavanagh Kyros J, Barrett T, Kim J, et al. An alternative splicing program promotes adipose tissue thermogenesis. elife. 2016;5: pubmed publisher
|
| Chen P, Qin L, Li G, Tellides G, Simons M. Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGF?)-dependent smooth muscle cell phenotype modulation. Sci Rep. 2016;6:33407 pubmed publisher
|
| Park S, Han S, Choi I, Kim B, Park S, Joe E, et al. Interplay between Leucine-Rich Repeat Kinase 2 (LRRK2) and p62/SQSTM-1 in Selective Autophagy. PLoS ONE. 2016;11:e0163029 pubmed publisher
|
| Justa Schuch D, Silva Garcia M, Pilla E, Engelke M, Kilisch M, Lenz C, et al. DPP9 is a novel component of the N-end rule pathway targeting the tyrosine kinase Syk. elife. 2016;5: pubmed publisher
|
| Watanabe S, Simon V, Durham N, Kemp B, Machihara S, Kemal K, et al. The HIV-1 late domain-2 S40A polymorphism in antiretroviral (or ART)-exposed individuals influences protease inhibitor susceptibility. Retrovirology. 2016;13:64 pubmed publisher
|
| Kang Y, Baker M, Liem M, Louber J, McKenzie M, Atukorala I, et al. Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability. elife. 2016;5: pubmed publisher
|
| Žuklys S, Handel A, Zhanybekova S, Govani F, Keller M, Maio S, et al. Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells. Nat Immunol. 2016;17:1206-1215 pubmed publisher
|
| Ahn J, Rechsteiner A, Strome S, Kelly W. A Conserved Nuclear Cyclophilin Is Required for Both RNA Polymerase II Elongation and Co-transcriptional Splicing in Caenorhabditis elegans. PLoS Genet. 2016;12:e1006227 pubmed publisher
|
| Koizumi S, Irie T, Hirayama S, Sakurai Y, Yashiroda H, Naguro I, et al. The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction. elife. 2016;5: pubmed publisher
|
| Vogan J, Zhang X, Youmans D, Regalado S, Johnson J, Hockemeyer D, et al. Minimized human telomerase maintains telomeres and resolves endogenous roles of H/ACA proteins, TCAB1, and Cajal bodies. elife. 2016;5: pubmed publisher
|
| Urban V, Dobrovolna J, Huhn D, Fryzelkova J, Bartek J, Janscak P. RECQ5 helicase promotes resolution of conflicts between replication and transcription in human cells. J Cell Biol. 2016;214:401-15 pubmed publisher
|
| Moretti I, Ciciliot S, Dyar K, Abraham R, Murgia M, Agatea L, et al. MRF4 negatively regulates adult skeletal muscle growth by repressing MEF2 activity. Nat Commun. 2016;7:12397 pubmed publisher
|
| Sousa R, Liao H, Cuellar J, Jin S, Valpuesta J, Jin A, et al. Clathrin-coat disassembly illuminates the mechanisms of Hsp70 force generation. Nat Struct Mol Biol. 2016;23:821-9 pubmed publisher
|
| Crippa V, Cicardi M, Ramesh N, Seguin S, Ganassi M, Bigi I, et al. The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity. Hum Mol Genet. 2016;25:3908-3924 pubmed publisher
|
| McLelland G, Lee S, McBride H, Fon E. Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system. J Cell Biol. 2016;214:275-91 pubmed publisher
|
| Wu J, Lei H, Zhang J, Chen X, Tang C, Wang W, et al. Momordin Ic, a new natural SENP1 inhibitor, inhibits prostate cancer cell proliferation. Oncotarget. 2016;7:58995-59005 pubmed publisher
|
| Guo Y, Ma J, Zheng Y, Li L, Gui X, Wang Q, et al. HPV16 E6 upregulates Aurora A expression. Oncol Lett. 2016;12:1387-1393 pubmed
|
| Gallagher C, Walter P. Ceapins inhibit ATF6α signaling by selectively preventing transport of ATF6α to the Golgi apparatus during ER stress. elife. 2016;5: pubmed publisher
|
| Gallagher C, Garri C, Cain E, Ang K, Wilson C, Chen S, et al. Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch. elife. 2016;5: pubmed publisher
|
| Miyazaki Y, Du X, Muramatsu S, Gomez C. An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron. Sci Transl Med. 2016;8:347ra94 pubmed publisher
|
| Xue L, Blythe E, Freiberger E, Mamrosh J, Hebert A, Reitsma J, et al. Valosin-containing protein (VCP)-Adaptor Interactions are Exceptionally Dynamic and Subject to Differential Modulation by a VCP Inhibitor. Mol Cell Proteomics. 2016;15:2970-86 pubmed publisher
|
| Li S, Qu Z, Haas M, Ngo L, Heo Y, Kang H, et al. The HSA21 gene EURL/C21ORF91 controls neurogenesis within the cerebral cortex and is implicated in the pathogenesis of Down Syndrome. Sci Rep. 2016;6:29514 pubmed publisher
|
| Bolar N, Golzio C, Zivná M, Hayot G, Van Hemelrijk C, Schepers D, et al. Heterozygous Loss-of-Function SEC61A1 Mutations Cause Autosomal-Dominant Tubulo-Interstitial and Glomerulocystic Kidney Disease with Anemia. Am J Hum Genet. 2016;99:174-87 pubmed publisher
|
| Hewitt G, Carroll B, Sarallah R, Correia Melo C, Ogrodnik M, Nelson G, et al. SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair. Autophagy. 2016;12:1917-1930 pubmed
|
| Zhang R, Miner J, Gorman M, Rausch K, Ramage H, White J, et al. A CRISPR screen defines a signal peptide processing pathway required by flaviviruses. Nature. 2016;535:164-8 pubmed
|
| Marceau C, Puschnik A, Majzoub K, Ooi Y, Brewer S, Fuchs G, et al. Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens. Nature. 2016;535:159-63 pubmed
|
| Fernández B, Fdez E, Gomez Suaga P, Gil F, Molina Villalba I, Ferrer I, et al. Iron overload causes endolysosomal deficits modulated by NAADP-regulated 2-pore channels and RAB7A. Autophagy. 2016;12:1487-506 pubmed publisher
|
| Park C, Lee S, Hong J, Suh Y, Park S, Suh B, et al. Disrupted-in-schizophrenia 1 (DISC1) and Syntaphilin collaborate to modulate axonal mitochondrial anchoring. Mol Brain. 2016;9:69 pubmed publisher
|
| Liu R, Moss B. Opposing Roles of Double-Stranded RNA Effector Pathways and Viral Defense Proteins Revealed with CRISPR-Cas9 Knockout Cell Lines and Vaccinia Virus Mutants. J Virol. 2016;90:7864-79 pubmed publisher
|
| Nakashima H, Ohkawara B, Ishigaki S, Fukudome T, Ito K, Tsushima M, et al. R-spondin 2 promotes acetylcholine receptor clustering at the neuromuscular junction via Lgr5. Sci Rep. 2016;6:28512 pubmed publisher
|
| Kathania M, Khare P, Zeng M, Cantarel B, Zhang H, Ueno H, et al. Itch inhibits IL-17-mediated colon inflammation and tumorigenesis by ROR-?t ubiquitination. Nat Immunol. 2016;17:997-1004 pubmed publisher
|
| Vanderperre B, Cermakova K, Escoffier J, Kaba M, Bender T, Nef S, et al. MPC1-like Is a Placental Mammal-specific Mitochondrial Pyruvate Carrier Subunit Expressed in Postmeiotic Male Germ Cells. J Biol Chem. 2016;291:16448-61 pubmed publisher
|
| Wagner S, Satpathy S, Beli P, Choudhary C. SPATA2 links CYLD to the TNF-? receptor signaling complex and modulates the receptor signaling outcomes. EMBO J. 2016;35:1868-84 pubmed publisher
|
| Michl C, Vivarelli F, Weigl J, De Nicola G, Canistro D, Paolini M, et al. The Chemopreventive Phytochemical Moringin Isolated from Moringa oleifera Seeds Inhibits JAK/STAT Signaling. PLoS ONE. 2016;11:e0157430 pubmed publisher
|
| Abdul Rehman S, Kristariyanto Y, Choi S, Nkosi P, Weidlich S, Labib K, et al. MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes. Mol Cell. 2016;63:146-55 pubmed publisher
|
| Qi Y, Yu J, Han W, Fan X, Qian H, Wei H, et al. A splicing isoform of TEAD4 attenuates the Hippo-YAP signalling to inhibit tumour proliferation. Nat Commun. 2016;7:ncomms11840 pubmed publisher
|
| Cai H, Yao W, Li L, Li X, Hu L, Mai R, et al. Cell-death-inducing DFFA-like Effector B Contributes to the Assembly of Hepatitis C Virus (HCV) Particles and Interacts with HCV NS5A. Sci Rep. 2016;6:27778 pubmed publisher
|
| Vos S, Pöllmann D, Caizzi L, Hofmann K, Rombaut P, Zimniak T, et al. Architecture and RNA binding of the human negative elongation factor. elife. 2016;5: pubmed publisher
|
| Lee J, Haddon D, Wand H, Price J, Diep V, Hall D, et al. Multiplex giant magnetoresistive biosensor microarrays identify interferon-associated autoantibodies in systemic lupus erythematosus. Sci Rep. 2016;6:27623 pubmed publisher
|
| Wang J, Farris A, Xu K, Wang P, Zhang X, Duong D, et al. GPRC5A suppresses protein synthesis at the endoplasmic reticulum to prevent radiation-induced lung tumorigenesis. Nat Commun. 2016;7:11795 pubmed publisher
|
| Hunter M, Grimsey N, Glass M. Sulfation of the FLAG epitope is affected by co-expression of G protein-coupled receptors in a mammalian cell model. Sci Rep. 2016;6:27316 pubmed publisher
|
| Jeong A, Han S, Lee S, Su Park J, Lu Y, Yu S, et al. Patient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathway. Sci Rep. 2016;6:27391 pubmed publisher
|
| Hao Y, Frey E, Yoon C, Wong H, Nestorovski D, Holzman L, et al. An evolutionarily conserved mechanism for cAMP elicited axonal regeneration involves direct activation of the dual leucine zipper kinase DLK. elife. 2016;5: pubmed publisher
|
| Hu X, Liu J, Jun H, Kim J, Qiao F. Multi-step coordination of telomerase recruitment in fission yeast through two coupled telomere-telomerase interfaces. elife. 2016;5: pubmed publisher
|
| Daugherty M, Schaller A, Geballe A, Malik H. Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals. elife. 2016;5: pubmed publisher
|
| Haas M, Ngo L, Li S, Schleich S, Qu Z, Vanyai H, et al. De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation. Cell Rep. 2016;15:2251-2265 pubmed publisher
|
| Zhou L, Hao J, Yuan Y, Peng R, Wang H, Ni D, et al. EIYMNVPV Motif is Essential for A1CF Nucleus Localization and A1CF (-8aa) Promotes Proliferation of MDA-MB-231 Cells via Up-Regulation of IL-6. Int J Mol Sci. 2016;17: pubmed publisher
|
| Li J, Zhang S, Hu Q, Zhang K, Jin J, Zheng X, et al. The NKD1/Rac1 feedback loop regulates the invasion and migration ability of hepatocarcinoma cells. Sci Rep. 2016;6:26971 pubmed publisher
|
| Dugar G, Svensson S, Bischler T, Wäldchen S, Reinhardt R, Sauer M, et al. The CsrA-FliW network controls polar localization of the dual-function flagellin mRNA in Campylobacter jejuni. Nat Commun. 2016;7:11667 pubmed publisher
|
| Zhang W, Ni P, Mou C, Zhang Y, Guo H, Zhao T, et al. Cops2 promotes pluripotency maintenance by Stabilizing Nanog Protein and Repressing Transcription. Sci Rep. 2016;6:26804 pubmed publisher
|
| Liu X, Seven A, Camacho M, Esser V, Xu J, Trimbuch T, et al. Functional synergy between the Munc13 C-terminal C1 and C2 domains. elife. 2016;5: pubmed publisher
|
| Lee Y, Lee J, Bae Y, Lee B, Kim E, Cho C, et al. Suppression of 14-3-3γ-mediated surface expression of ANO1 inhibits cancer progression of glioblastoma cells. Sci Rep. 2016;6:26413 pubmed publisher
|
| Liang Y, Lee C, Yao Y, Lai C, Schmitz M, Yang W. SUMO5, a Novel Poly-SUMO Isoform, Regulates PML Nuclear Bodies. Sci Rep. 2016;6:26509 pubmed publisher
|
| Augustine R, York S, Rytz T, Vierstra R. Defining the SUMO System in Maize: SUMOylation Is Up-Regulated during Endosperm Development and Rapidly Induced by Stress. Plant Physiol. 2016;171:2191-210 pubmed publisher
|
| Tang J, DROKHLYANSKY E, Etemad B, Rudolph S, Guo B, Wang S, et al. Detection and manipulation of live antigen-expressing cells using conditionally stable nanobodies. elife. 2016;5: pubmed publisher
|
| Gerin I, Ury B, Breloy I, Bouchet Seraphin C, Bolsée J, Halbout M, et al. ISPD produces CDP-ribitol used by FKTN and FKRP to transfer ribitol phosphate onto α-dystroglycan. Nat Commun. 2016;7:11534 pubmed publisher
|
| Wang X, Li Q, Yuan W, Cao Z, Qi B, Kumar S, et al. The cytosolic Fe-S cluster assembly component MET18 is required for the full enzymatic activity of ROS1 in active DNA demethylation. Sci Rep. 2016;6:26443 pubmed publisher
|
| Li J, Song J, Zaytseva Y, Liu Y, Rychahou P, Jiang K, et al. An obligatory role for neurotensin in high-fat-diet-induced obesity. Nature. 2016;533:411-5 pubmed publisher
|
| Speight P, Kofler M, Szaszi K, Kapus A. Context-dependent switch in chemo/mechanotransduction via multilevel crosstalk among cytoskeleton-regulated MRTF and TAZ and TGF?-regulated Smad3. Nat Commun. 2016;7:11642 pubmed publisher
|
| Link S, Grund S, Diederichs S. Alternative splicing affects the subcellular localization of Drosha. Nucleic Acids Res. 2016;44:5330-43 pubmed publisher
|
| Barry W, Thummel C. The Drosophila HNF4 nuclear receptor promotes glucose-stimulated insulin secretion and mitochondrial function in adults. elife. 2016;5: pubmed publisher
|
| Lee S, Kang M, Park J, Lee G, Ting A, Rhee H. APEX Fingerprinting Reveals the Subcellular Localization of Proteins of Interest. Cell Rep. 2016;15:1837-47 pubmed publisher
|
| Najibi M, Labed S, Visvikis O, IRAZOQUI J. An Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host Defense. Cell Rep. 2016;15:1728-42 pubmed publisher
|
| Langlands H, Blain P, Jowsey P. Fe65 Is Phosphorylated on Ser289 after UV-Induced DNA Damage. PLoS ONE. 2016;11:e0155056 pubmed publisher
|
| Seymour M, Ji L, Santos A, Kamei M, Sasaki T, Basenko E, et al. Histone H1 Limits DNA Methylation in Neurospora crassa. G3 (Bethesda). 2016;6:1879-89 pubmed publisher
|
| Messina G, Atterrato M, Fanti L, Giordano E, Dimitri P. Expression of human Cfdp1 gene in Drosophila reveals new insights into the function of the evolutionarily conserved BCNT protein family. Sci Rep. 2016;6:25511 pubmed publisher
|
| López Mateo I, Arruabarrena Aristorena A, Artaza Irigaray C, López J, Calvo E, Belandia B. HEY1 functions are regulated by its phosphorylation at Ser-68. Biosci Rep. 2016;36: pubmed publisher
|
| Jules J, Chen W, Feng X, Li Y. CCAAT/Enhancer-binding Protein ? (C/EBP?) Is Important for Osteoclast Differentiation and Activity. J Biol Chem. 2016;291:16390-403 pubmed publisher
|
| Chen Y, Pan K, Wang P, Cao Z, Wang W, Wang S, et al. HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis. J Biol Chem. 2016;291:12688-705 pubmed publisher
|
| Kim H, Oh J, Choi S, Nam Y, Jo A, Kwon A, et al. Down-regulation of p21-activated serine/threonine kinase 1 is involved in loss of mesencephalic dopamine neurons. Mol Brain. 2016;9:45 pubmed publisher
|
| Zhang J, Lachance V, Schaffner A, Li X, Fedick A, Kaye L, et al. A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects. PLoS Genet. 2016;12:e1005848 pubmed publisher
|
| Kennedy E, Bogerd H, Kornepati A, Kang D, Ghoshal D, Marshall J, et al. Posttranscriptional m(6)A Editing of HIV-1 mRNAs Enhances Viral Gene Expression. Cell Host Microbe. 2016;19:675-85 pubmed publisher
|
| Carofino B, Ayanga B, Tracey L, Brooke Bisschop T, Justice M. PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL. Biol Open. 2016;5:645-53 pubmed publisher
|
| Link L, Howley B, Hussey G, Howe P. PCBP1/HNRNP E1 Protects Chromosomal Integrity by Translational Regulation of CDC27. Mol Cancer Res. 2016;14:634-46 pubmed publisher
|
| Langellotti S, Romano V, Romano G, Klima R, Feiguin F, Cragnaz L, et al. A novel Drosophila model of TDP-43 proteinopathies: N-terminal sequences combined with the Q/N domain induce protein functional loss and locomotion defects. Dis Model Mech. 2016;9:659-69 pubmed publisher
|
| Tsai M, Phillips C, Ranaghan M, Tsai C, Wu Y, Willliams C, et al. Dual functions of a small regulatory subunit in the mitochondrial calcium uniporter complex. elife. 2016;5: pubmed publisher
|
| Jackson V, Mehmood S, Chavent M, Roversi P, Carrasquero M, del Toro D, et al. Super-complexes of adhesion GPCRs and neural guidance receptors. Nat Commun. 2016;7:11184 pubmed publisher
|
| Soh H, Venkatesan N, Veena M, Ravichandran S, Zinabadi A, Basak S, et al. Cystatin E/M Suppresses Tumor Cell Growth through Cytoplasmic Retention of NF-?B. Mol Cell Biol. 2016;36:1776-92 pubmed publisher
|
| Okumura F, Uematsu K, Byrne S, Hirano M, Joo Okumura A, Nishikimi A, et al. Parallel Regulation of von Hippel-Lindau Disease by pVHL-Mediated Degradation of B-Myb and Hypoxia-Inducible Factor ?. Mol Cell Biol. 2016;36:1803-17 pubmed publisher
|
| Chapdelaine P, Gerard C, Sanchez N, Cherif K, Rousseau J, Ouellet D, et al. Development of an AAV9 coding for a 3XFLAG-TALEfrat#8-VP64 able to increase in vivo the human frataxin in YG8R mice. Gene Ther. 2016;23:606-14 pubmed publisher
|
| Pinz S, Unser S, Rascle A. Signal transducer and activator of transcription STAT5 is recruited to c-Myc super-enhancer. BMC Mol Biol. 2016;17:10 pubmed publisher
|
| Uto T, Fukaya T, Takagi H, Arimura K, Nakamura T, Kojima N, et al. Clec4A4 is a regulatory receptor for dendritic cells that impairs inflammation and T-cell immunity. Nat Commun. 2016;7:11273 pubmed publisher
|
| Palu R, Thummel C. Sir2 Acts through Hepatocyte Nuclear Factor 4 to maintain insulin Signaling and Metabolic Homeostasis in Drosophila. PLoS Genet. 2016;12:e1005978 pubmed publisher
|
| Breslin J, Daines D, Doggett T, Kurtz K, Souza Smith F, Zhang X, et al. Rnd3 as a Novel Target to Ameliorate Microvascular Leakage. J Am Heart Assoc. 2016;5:e003336 pubmed publisher
|
| Percher A, Ramakrishnan S, Thinon E, Yuan X, Yount J, Hang H. Mass-tag labeling reveals site-specific and endogenous levels of protein S-fatty acylation. Proc Natl Acad Sci U S A. 2016;113:4302-7 pubmed publisher
|
| Kang J, Lee J, Hong D, Lee S, Kim N, Lee W, et al. Renal cell carcinoma escapes death by p53 depletion through transglutaminase 2-chaperoned autophagy. Cell Death Dis. 2016;7:e2163 pubmed publisher
|
| Panday A, Grove A. The high mobility group protein HMO1 functions as a linker histone in yeast. Epigenetics Chromatin. 2016;9:13 pubmed publisher
|
| Ma B, Cheng H, Gao R, Mu C, Chen L, Wu S, et al. Zyxin-Siah2-Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathways. Nat Commun. 2016;7:11123 pubmed publisher
|
| Meng L, Chen C, Yan D. Regulation of Gap Junction Dynamics by UNC-44/ankyrin and UNC-33/CRMP through VAB-8 in C. elegans Neurons. PLoS Genet. 2016;12:e1005948 pubmed publisher
|
| Chen Y, Zhou C, Ji W, Mei Z, Hu B, Zhang W, et al. ELL targets c-Myc for proteasomal degradation and suppresses tumour growth. Nat Commun. 2016;7:11057 pubmed publisher
|
| Zhao W, Liu J, Zhang X, Deng L. MLL5 maintains spindle bipolarity by preventing aberrant cytosolic aggregation of PLK1. J Cell Biol. 2016;212:829-43 pubmed publisher
|
| Ortuno D, Carlisle H, Miller S. Does inactivation of USP14 enhance degradation of proteasomal substrates that are associated with neurodegenerative diseases?. F1000Res. 2016;5:137 pubmed publisher
|
| Rasheedi S, Shun M, Serrao E, Sowd G, Qian J, Hao C, et al. The Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Subunit of the Capsid-recruited Pre-messenger RNA Cleavage Factor I (CFIm) Complex Mediates HIV-1 Integration into Genes. J Biol Chem. 2016;291:11809-19 pubmed publisher
|
| Byrd P, Stewart G, Smith A, Eaton C, Taylor A, Guy C, et al. A Hypomorphic PALB2 Allele Gives Rise to an Unusual Form of FA-N Associated with Lymphoid Tumour Development. PLoS Genet. 2016;12:e1005945 pubmed publisher
|
| Jin H, Lee K, Kim Y, Oh H, Maeng Y, Kim T, et al. Scaffold protein FHL2 facilitates MDM2-mediated degradation of IER3 to regulate proliferation of cervical cancer cells. Oncogene. 2016;35:5106-18 pubmed publisher
|
| Murai K, Sun G, Ye P, Tian E, Yang S, Cui Q, et al. The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model. Nat Commun. 2016;7:10965 pubmed publisher
|
| Bartuzi P, Billadeau D, Favier R, Rong S, Dekker D, Fedoseienko A, et al. CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL. Nat Commun. 2016;7:10961 pubmed publisher
|
| Utt A, Quirin T, Saul S, Hellström K, Ahola T, Merits A. Versatile Trans-Replication Systems for Chikungunya Virus Allow Functional Analysis and Tagging of Every Replicase Protein. PLoS ONE. 2016;11:e0151616 pubmed publisher
|
| Christensen D, Ejlerskov P, Rasmussen I, Vilhardt F. Reciprocal signals between microglia and neurons regulate α-synuclein secretion by exophagy through a neuronal cJUN-N-terminal kinase-signaling axis. J Neuroinflammation. 2016;13:59 pubmed publisher
|
| Choi S, Gearhart M, Cui Z, Bosnakovski D, Kim M, Schennum N, et al. DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes. Nucleic Acids Res. 2016;44:5161-73 pubmed publisher
|
| Myers S, Peddada S, Chatterjee N, Friedrich T, Tomoda K, Krings G, et al. SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells. elife. 2016;5:e10647 pubmed publisher
|
| Chen Y, Bharill S, Altun Z, O HAGAN R, Coblitz B, Isacoff E, et al. Caenorhabditis elegans paraoxonase-like proteins control the functional expression of DEG/ENaC mechanosensory proteins. Mol Biol Cell. 2016;27:1272-85 pubmed publisher
|
| Mavuluri J, Beesetti S, Surabhi R, Kremerskothen J, Venkatraman G, Rayala S. Phosphorylation-Dependent Regulation of the DNA Damage Response of Adaptor Protein KIBRA in Cancer Cells. Mol Cell Biol. 2016;36:1354-65 pubmed publisher
|
| Lee D, Wang Y, Kalaitzidis D, Ramachandran J, Eda H, Sykes D, et al. Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancy. J Clin Invest. 2016;126:1300-10 pubmed publisher
|
| Guo D, Cui H, Zhang Q, Morgan D, Thedens D, Nishimura D, et al. The BBSome Controls Energy Homeostasis by Mediating the Transport of the Leptin Receptor to the Plasma Membrane. PLoS Genet. 2016;12:e1005890 pubmed publisher
|
| Hyrsová L, Smutny T, Carazo A, Moravcik S, Mandíková J, Trejtnar F, et al. The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 coactivator. Br J Pharmacol. 2016;173:1703-15 pubmed publisher
|
| Lamar K, Miller T, Dellefave Castillo L, McNally E. Genotype-Specific Interaction of Latent TGFβ Binding Protein 4 with TGFβ. PLoS ONE. 2016;11:e0150358 pubmed publisher
|
| McLaughlin D, Coey C, Yang W, Drohat A, Matunis M. Characterizing Requirements for Small Ubiquitin-like Modifier (SUMO) Modification and Binding on Base Excision Repair Activity of Thymine-DNA Glycosylase in Vivo. J Biol Chem. 2016;291:9014-24 pubmed publisher
|
| Xu M, Bian S, Li J, He J, Chen H, Ge L, et al. MeCP2 suppresses LIN28A expression via binding to its methylated-CpG islands in pancreatic cancer cells. Oncotarget. 2016;7:14476-85 pubmed publisher
|
| Zhang W, Wu X, Shi T, Xu H, Yi J, Shen H, et al. Regulation of Transcription Factor Yin Yang 1 by SET7/9-mediated Lysine Methylation. Sci Rep. 2016;6:21718 pubmed publisher
|
| Harris D, Chandrasekharan U, Bandyopadhyay S, Willard B, DiCorleto P. PRMT5-Mediated Methylation of NF-κB p65 at Arg174 Is Required for Endothelial CXCL11 Gene Induction in Response to TNF-α and IFN-γ Costimulation. PLoS ONE. 2016;11:e0148905 pubmed publisher
|
| Jung B, Padula D, Burtscher I, Landerer C, Lutter D, Theis F, et al. Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation. PLoS ONE. 2016;11:e0149477 pubmed publisher
|
| Hu M, Bai Y, Zhang C, Liu F, Cui Z, Chen J, et al. Liver-Enriched Gene 1, a Glycosylated Secretory Protein, Binds to FGFR and Mediates an Anti-stress Pathway to Protect Liver Development in Zebrafish. PLoS Genet. 2016;12:e1005881 pubmed publisher
|
| Sharma V, Young L, Allison A, Owen K. Registered report: Diverse somatic mutation patterns and pathway alterations in human cancers. elife. 2016;5: pubmed publisher
|
| Hwang S, Jang S, Kim M, Kim L, Kim B, Kim H, et al. YY1 inhibits differentiation and function of regulatory T cells by blocking Foxp3 expression and activity. Nat Commun. 2016;7:10789 pubmed publisher
|
| Culver B, DeClercq J, Dolgalev I, Yu M, Ma B, Heguy A, et al. Huntington's Disease Protein Huntingtin Associates with its own mRNA. J Huntingtons Dis. 2016;5:39-51 pubmed publisher
|
| Li L, Yu J, Li Y, Wang J, Li S, Zhang L, et al. Guanylate-Binding Protein 1, an Interferon-Induced GTPase, Exerts an Antiviral Activity against Classical Swine Fever Virus Depending on Its GTPase Activity. J Virol. 2016;90:4412-4426 pubmed publisher
|
| Hatori Y, Yan Y, Schmidt K, Furukawa E, Hasan N, Yang N, et al. Neuronal differentiation is associated with a redox-regulated increase of copper flow to the secretory pathway. Nat Commun. 2016;7:10640 pubmed publisher
|
| Chen S, Blank M, Iyer A, Huang B, Wang L, Grummt I, et al. SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing. Nat Commun. 2016;7:10734 pubmed publisher
|
| Tung H, Wei S, Lo H, Chao Y. Baculovirus IE2 Stimulates the Expression of Heat Shock Proteins in Insect and Mammalian Cells to Facilitate Its Proper Functioning. PLoS ONE. 2016;11:e0148578 pubmed publisher
|
| Oh S, Onomoto K, Wakimoto M, Onoguchi K, Ishidate F, Fujiwara T, et al. Leader-Containing Uncapped Viral Transcript Activates RIG-I in Antiviral Stress Granules. PLoS Pathog. 2016;12:e1005444 pubmed publisher
|
| Mori H, Yao Y, Learman B, Kurozumi K, Ishida J, Ramakrishnan S, et al. Induction of WNT11 by hypoxia and hypoxia-inducible factor-1α regulates cell proliferation, migration and invasion. Sci Rep. 2016;6:21520 pubmed publisher
|
| Awate S, De Benedetti A. TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint. BMC Mol Biol. 2016;17:3 pubmed publisher
|
| Hatai H, Lepelley A, Zeng W, Hayden M, Ghosh S. Toll-Like Receptor 11 (TLR11) Interacts with Flagellin and Profilin through Disparate Mechanisms. PLoS ONE. 2016;11:e0148987 pubmed publisher
|
| Kaya Okur H, Das A, Taylor R, Bagchi I, Bagchi M. Roles of Estrogen Receptor-α and the Coactivator MED1 During Human Endometrial Decidualization. Mol Endocrinol. 2016;30:302-13 pubmed publisher
|
| Zhong X, Rao X, Yi H, Lin X, Huang X, Yu X. Co-expression of Dorsal and Rel2 Negatively Regulates Antimicrobial Peptide Expression in the Tobacco Hornworm Manduca sexta. Sci Rep. 2016;6:20654 pubmed publisher
|
| Le Pen J, Maillet L, Sarosiek K, Vuillier C, Gautier F, Montessuit S, et al. Constitutive p53 heightens mitochondrial apoptotic priming and favors cell death induction by BH3 mimetic inhibitors of BCL-xL. Cell Death Dis. 2016;7:e2083 pubmed publisher
|
| Di Magno L, Basile A, Coni S, Manni S, Sdruscia G, D Amico D, et al. The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint. Oncotarget. 2016;7:9538-49 pubmed publisher
|
| Tenga A, Beard J, Takwi A, Wang Y, Chen T. Regulation of Nuclear Receptor Nur77 by miR-124. PLoS ONE. 2016;11:e0148433 pubmed publisher
|
| Sen A, Cox R. Clueless is a conserved ribonucleoprotein that binds the ribosome at the mitochondrial outer membrane. Biol Open. 2016;5:195-203 pubmed publisher
|
| Lopez J, Bessou M, Riley J, Giampazolias E, Todt F, Rochegüe T, et al. Mito-priming as a method to engineer Bcl-2 addiction. Nat Commun. 2016;7:10538 pubmed publisher
|
| Kwon D, Eom G, Ko J, Shin S, Joung H, Choe N, et al. MDM2 E3 ligase-mediated ubiquitination and degradation of HDAC1 in vascular calcification. Nat Commun. 2016;7:10492 pubmed publisher
|
| Yang Y, Wang L, Bell P, McMenamin D, He Z, White J, et al. A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice. Nat Biotechnol. 2016;34:334-8 pubmed publisher
|
| Bouge A, Parmentier M. Tau excess impairs mitosis and kinesin-5 function, leading to aneuploidy and cell death. Dis Model Mech. 2016;9:307-19 pubmed publisher
|
| Sakurai T, Kamiyoshi A, Kawate H, Mori C, Watanabe S, Tanaka M, et al. A non-inheritable maternal Cas9-based multiple-gene editing system in mice. Sci Rep. 2016;6:20011 pubmed publisher
|
| Bindesbøll C, Tan S, Bott D, Cho T, Tamblyn L, MacPherson L, et al. TCDD-inducible poly-ADP-ribose polymerase (TIPARP/PARP7) mono-ADP-ribosylates and co-activates liver X receptors. Biochem J. 2016;473:899-910 pubmed publisher
|
| Müller M, Fierz B, Bittova L, Liszczak G, Muir T. A two-state activation mechanism controls the histone methyltransferase Suv39h1. Nat Chem Biol. 2016;12:188-93 pubmed publisher
|
| Tashiro S, Handa T, Matsuda A, Ban T, Takigawa T, Miyasato K, et al. Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing. Nat Commun. 2016;7:10393 pubmed publisher
|
| Wang Y, Wu Q, Yang P, Wang C, Liu J, Ding W, et al. LSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brain. Nat Commun. 2016;7:10481 pubmed publisher
|
| Basu A, Tomar A, Dasari V, Mishra R, Khosla S. DNMT3L enables accumulation and inheritance of epimutations in transgenic Drosophila. Sci Rep. 2016;6:19572 pubmed publisher
|
| Wang S, Hu Y, Yang J, Smith C, Richardson A, Yamakoshi Y, et al. Fam83h null mice support a neomorphic mechanism for human ADHCAI. Mol Genet Genomic Med. 2016;4:46-67 pubmed publisher
|
| Zheng F, Yue C, Li G, He B, Cheng W, Wang X, et al. Nuclear AURKA acquires kinase-independent transactivating function to enhance breast cancer stem cell phenotype. Nat Commun. 2016;7:10180 pubmed publisher
|
| Mark K, Loveless T, Toczyski D. Isolation of ubiquitinated substrates by tandem affinity purification of E3 ligase-polyubiquitin-binding domain fusions (ligase traps). Nat Protoc. 2016;11:291-301 pubmed publisher
|
| Wani A, Boettiger A, Schorderet P, Ergun A, Munger C, Sadreyev R, et al. Chromatin topology is coupled to Polycomb group protein subnuclear organization. Nat Commun. 2016;7:10291 pubmed publisher
|
| Asano Y, Kawase T, Okabe A, Tsutsumi S, Ichikawa H, Tatebe S, et al. IER5 generates a novel hypo-phosphorylated active form of HSF1 and contributes to tumorigenesis. Sci Rep. 2016;6:19174 pubmed publisher
|
| Akdoğan E, Tardu M, Garipler G, Baytek G, Kavakli I, Dunn C. Reduced Glucose Sensation Can Increase the Fitness of Saccharomyces cerevisiae Lacking Mitochondrial DNA. PLoS ONE. 2016;11:e0146511 pubmed publisher
|
| Song P, Li S, Wu H, Gao R, Rao G, Wang D, et al. Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's disease. Protein Cell. 2016;7:114-29 pubmed publisher
|
| Huang R, Fang P, Hao Z, Kay B. Directed Evolution of a Highly Specific FN3 Monobody to the SH3 Domain of Human Lyn Tyrosine Kinase. PLoS ONE. 2016;11:e0145872 pubmed publisher
|
| Sansó M, Levin R, Lipp J, Wang V, Greifenberg A, Quezada E, et al. P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates. Genes Dev. 2016;30:117-31 pubmed publisher
|
| Aini H, Itaka K, Fujisawa A, Uchida H, Uchida S, Fukushima S, et al. Messenger RNA delivery of a cartilage-anabolic transcription factor as a disease-modifying strategy for osteoarthritis treatment. Sci Rep. 2016;6:18743 pubmed publisher
|
| Wu W, Xu C, Ling X, Fan C, Buckley B, Chernov M, et al. Targeting RING domains of Mdm2-MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cells. Cell Death Dis. 2015;6:e2035 pubmed publisher
|
| Kim S, Park S, Shim S, Park S, Kim K, Jeong S, et al. Bay 61-3606 Sensitizes TRAIL-Induced Apoptosis by Downregulating Mcl-1 in Breast Cancer Cells. PLoS ONE. 2015;10:e0146073 pubmed publisher
|
| Pedersen S, Chan W, Jattani R, Mackie d, Pomerantz J. Negative Regulation of CARD11 Signaling and Lymphoma Cell Survival by the E3 Ubiquitin Ligase RNF181. Mol Cell Biol. 2015;36:794-808 pubmed publisher
|
| Chen A, Kim S, Shepardson N, Patel S, Hong S, Selkoe D. Physical and functional interaction between the α- and γ-secretases: A new model of regulated intramembrane proteolysis. J Cell Biol. 2015;211:1157-76 pubmed publisher
|
| Fischer F, Langer J, Osiewacz H. Identification of potential mitochondrial CLPXP protease interactors and substrates suggests its central role in energy metabolism. Sci Rep. 2015;5:18375 pubmed publisher
|
| Nizialek E, Sankunny M, Niazi F, Eng C. Cancer-predisposition gene KLLN maintains pericentric H3K9 trimethylation protecting genomic stability. Nucleic Acids Res. 2016;44:3586-94 pubmed publisher
|
| Overton J, Komiya Y, Mezzacappa C, Nama K, Cai N, Lou L, et al. Hepatocystin is Essential for TRPM7 Function During Early Embryogenesis. Sci Rep. 2015;5:18395 pubmed publisher
|
| Saleh T, Jankowski W, Sriram G, Rossi P, Shah S, Lee K, et al. Cyclophilin A promotes cell migration via the Abl-Crk signaling pathway. Nat Chem Biol. 2016;12:117-23 pubmed publisher
|
| Zhang H, Zhan C, Ke J, Xue Z, Zhang A, Xu K, et al. EGFR kinase domain mutation positive lung cancers are sensitive to intrapleural perfusion with hyperthermic chemotherapy (IPHC) complete treatment. Oncotarget. 2016;7:3367-78 pubmed publisher
|
| Jun M, Han J, Lee Y, Jang D, Kaang B, Lee J. TMEM106B, a frontotemporal lobar dementia (FTLD) modifier, associates with FTD-3-linked CHMP2B, a complex of ESCRT-III. Mol Brain. 2015;8:85 pubmed publisher
|
| Mattijssen S, Maraia R. LARP4 Is Regulated by Tumor Necrosis Factor Alpha in a Tristetraprolin-Dependent Manner. Mol Cell Biol. 2016;36:574-84 pubmed publisher
|
| Cabedo Martinez A, Weinhäupl K, Lee W, Wolff N, Storch B, Żerko S, et al. Biochemical and Structural Characterization of the Interaction between the Siderocalin NGAL/LCN2 (Neutrophil Gelatinase-associated Lipocalin/Lipocalin 2) and the N-terminal Domain of Its Endocytic Receptor SLC22A17. J Biol Chem. 2016;291:2917-30 pubmed publisher
|
| Farrow P, Khodosevich K, Sapir Y, Schulmann A, Aslam M, Stern Bach Y, et al. Auxiliary subunits of the CKAMP family differentially modulate AMPA receptor properties. elife. 2015;4:e09693 pubmed publisher
|
| Schoborg T, Zajac A, Fagerstrom C, Guillen R, Rusan N. An Asp-CaM complex is required for centrosome-pole cohesion and centrosome inheritance in neural stem cells. J Cell Biol. 2015;211:987-98 pubmed publisher
|
| Sengelaub C, Navrazhina K, Ross J, Halberg N, Tavazoie S. PTPRN2 and PLCβ1 promote metastatic breast cancer cell migration through PI(4,5)P2-dependent actin remodeling. EMBO J. 2016;35:62-76 pubmed publisher
|
| Ni Y, Tao L, Chen C, Song H, Li Z, Gao Y, et al. The Deubiquitinase USP17 Regulates the Stability and Nuclear Function of IL-33. Int J Mol Sci. 2015;16:27956-66 pubmed publisher
|
| Miyamoto T, Kim D, Knox J, Johnson E, Mucke L. Increasing the Receptor Tyrosine Kinase EphB2 Prevents Amyloid-β-induced Depletion of Cell Surface Glutamate Receptors by a Mechanism That Requires the PDZ-binding Motif of EphB2 and Neuronal Activity. J Biol Chem. 2016;291:1719-34 pubmed publisher
|
| Boltengagen M, Huang A, Boltengagen A, Trixl L, Lindner H, Kremser L, et al. A novel role for the histone acetyltransferase Hat1 in the CENP-A/CID assembly pathway in Drosophila melanogaster. Nucleic Acids Res. 2016;44:2145-59 pubmed publisher
|
| Yerlikaya S, Meusburger M, Kumari R, Huber A, Anrather D, Costanzo M, et al. TORC1 and TORC2 work together to regulate ribosomal protein S6 phosphorylation in Saccharomyces cerevisiae. Mol Biol Cell. 2016;27:397-409 pubmed publisher
|
| Zhai Z, An H, Wang G, Luo Y, Hao Y. Functional role of pyruvate kinase from Lactobacillus bulgaricus in acid tolerance and identification of its transcription factor by bacterial one-hybrid. Sci Rep. 2015;5:17024 pubmed publisher
|
| Wang X, Liu Y, Chen H, Mei L, He C, Jiang L, et al. LEF-1 Regulates Tyrosinase Gene Transcription In Vitro. PLoS ONE. 2015;10:e0143142 pubmed publisher
|
| Zhang L, Tran N, Su H, Wang R, Lu Y, Tang H, et al. Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing. elife. 2015;4: pubmed publisher
|
| Tsai Y, Lapina M, Bhushan S, Mueller Cajar O. Identification and characterization of multiple rubisco activases in chemoautotrophic bacteria. Nat Commun. 2015;6:8883 pubmed publisher
|
| Sun Y, Fu A, Xu W, Chao J, Moshiach S, Morris S. Myeloid leukemia factor 1 interfered with Bcl-XL to promote apoptosis and its function was regulated by 14-3-3. J Physiol Biochem. 2015;71:807-21 pubmed publisher
|
| He X, Wang L, Yan J, Yuan C, Witze E, Hua X. Menin localization in cell membrane compartment. Cancer Biol Ther. 2016;17:114-22 pubmed publisher
|
| Lee S, Jeong J, Oh C, Park S, Kim J, Kim H, et al. Pyruvate Dehydrogenase Kinase 4 Promotes Vascular Calcification via SMAD1/5/8 Phosphorylation. Sci Rep. 2015;5:16577 pubmed publisher
|
| Shirozu R, Yashiroda H, Murata S. Proteasome Impairment Induces Recovery of Mitochondrial Membrane Potential and an Alternative Pathway of Mitochondrial Fusion. Mol Cell Biol. 2016;36:347-62 pubmed publisher
|
| Chen P, Chen H, Acharya D, Rando O, Fazzio T. R loops regulate promoter-proximal chromatin architecture and cellular differentiation. Nat Struct Mol Biol. 2015;22:999-1007 pubmed publisher
|
| Huang H, Alvarez S, Bindbeutel R, Shen Z, Naldrett M, Evans B, et al. Identification of Evening Complex Associated Proteins in Arabidopsis by Affinity Purification and Mass Spectrometry. Mol Cell Proteomics. 2016;15:201-17 pubmed publisher
|
| Zeke A, Bastys T, Alexa A, Garai Ã, Mészáros B, Kirsch K, et al. Systematic discovery of linear binding motifs targeting an ancient protein interaction surface on MAP kinases. Mol Syst Biol. 2015;11:837 pubmed publisher
|
| Qureshi R, Yildirim O, Gasser A, Basmadjian C, Zhao Q, Wilmet J, et al. FL3, a Synthetic Flavagline and Ligand of Prohibitins, Protects Cardiomyocytes via STAT3 from Doxorubicin Toxicity. PLoS ONE. 2015;10:e0141826 pubmed publisher
|
| Xu D, Shan B, Lee B, Zhu K, Zhang T, Sun H, et al. Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system. elife. 2015;4:e10510 pubmed publisher
|
| Haq T, Richards M, Burgess S, Gallego P, Yeoh S, O Regan L, et al. Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization. Nat Commun. 2015;6:8771 pubmed publisher
|
| Wang B, Ma A, Zhang L, Jin W, Qian Y, Xu G, et al. POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation. Nat Commun. 2015;6:8704 pubmed publisher
|
| Chauhan S, Ahmed Z, Bradfute S, Arko Mensah J, Mandell M, Won Choi S, et al. Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential. Nat Commun. 2015;6:8620 pubmed publisher
|
| Ryu T, Spatola B, Delabaere L, Bowlin K, Hopp H, Kunitake R, et al. Heterochromatic breaks move to the nuclear periphery to continue recombinational repair. Nat Cell Biol. 2015;17:1401-11 pubmed publisher
|
| Thakore P, D Ippolito A, Song L, Safi A, Shivakumar N, Kabadi A, et al. Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements. Nat Methods. 2015;12:1143-9 pubmed publisher
|
| Li M, Quan C, Toth R, Campbell D, MacKintosh C, Wang H, et al. Fasting and Systemic Insulin Signaling Regulate Phosphorylation of Brain Proteins That Modulate Cell Morphology and Link to Neurological Disorders. J Biol Chem. 2015;290:30030-41 pubmed publisher
|
| Bridoux L, Deneyer N, Bergiers I, Rezsohazy R. Molecular Analysis of the HOXA2-Dependent Degradation of RCHY1. PLoS ONE. 2015;10:e0141347 pubmed publisher
|
| Albertos P, Romero Puertas M, Tatematsu K, Mateos I, Sánchez Vicente I, Nambara E, et al. S-nitrosylation triggers ABI5 degradation to promote seed germination and seedling growth. Nat Commun. 2015;6:8669 pubmed publisher
|
| Reeder J, Kwak Y, McNamara R, Forst C, D Orso I. HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells. elife. 2015;4: pubmed publisher
|
| Peschek J, Acosta Alvear D, Mendez A, Walter P. A conformational RNA zipper promotes intron ejection during non-conventional XBP1 mRNA splicing. EMBO Rep. 2015;16:1688-98 pubmed publisher
|
| Preissler S, Chambers J, Crespillo Casado A, Avezov E, Miranda E, Perez J, et al. Physiological modulation of BiP activity by trans-protomer engagement of the interdomain linker. elife. 2015;4:e08961 pubmed publisher
|
| Lu R, Herrera B, Eshleman H, Fu Y, Bloom A, Li Z, et al. Shigella Effector OspB Activates mTORC1 in a Manner That Depends on IQGAP1 and Promotes Cell Proliferation. PLoS Pathog. 2015;11:e1005200 pubmed publisher
|
| Palam L, Gore J, Craven K, Wilson J, Korc M. Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma. Cell Death Dis. 2015;6:e1913 pubmed publisher
|
| Ye M, Tang Y, Tang S, Liu J, Wu K, Yao S, et al. STIP is a critical nuclear scaffolding protein linking USP7 to p53-Mdm2 pathway regulation. Oncotarget. 2015;6:34718-31 pubmed publisher
|
| Nishi K, Takahashi T, Suzawa M, Miyakawa T, Nagasawa T, Ming Y, et al. Control of the localization and function of a miRNA silencing component TNRC6A by Argonaute protein. Nucleic Acids Res. 2015;43:9856-73 pubmed publisher
|
| Chen P, Weng J, Hsu P, Shew J, Huang Y, Lee W. NPGPx modulates CPEB2-controlled HIF-1α RNA translation in response to oxidative stress. Nucleic Acids Res. 2015;43:9393-404 pubmed publisher
|
| Deng X, Zhou H, Zhang G, Wang W, Mao L, Zhou X, et al. Sgf73, a subunit of SAGA complex, is required for the assembly of RITS complex in fission yeast. Sci Rep. 2015;5:14707 pubmed publisher
|
| Zhong N, Loppnau P, Seitova A, Ravichandran M, Fenner M, Jain H, et al. Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins. PLoS ONE. 2015;10:e0139695 pubmed publisher
|
| Nakakido M, Deng Z, Suzuki T, Dohmae N, Nakamura Y, Hamamoto R. PRMT6 increases cytoplasmic localization of p21CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents. Oncotarget. 2015;6:30957-67 pubmed publisher
|
| Mancias J, Pontano Vaites L, Nissim S, Biancur D, Kim A, Wang X, et al. Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis. elife. 2015;4: pubmed publisher
|
| Ambroise G, Portier A, Roders N, Arnoult D, Vazquez A. Subcellular localization of PUMA regulates its pro-apoptotic activity in Burkitt's lymphoma B cells. Oncotarget. 2015;6:38181-94 pubmed publisher
|
| Tong X, Zhang D, Guha A, Arthurs B, Cazares V, Gupta N, et al. CUL4-DDB1-CDT2 E3 Ligase Regulates the Molecular Clock Activity by Promoting Ubiquitination-Dependent Degradation of the Mammalian CRY1. PLoS ONE. 2015;10:e0139725 pubmed publisher
|
| Castella M, Jacquemont C, Thompson E, Yeo J, Cheung R, Huang J, et al. FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2. PLoS Genet. 2015;11:e1005563 pubmed publisher
|
| Ichida Y, Utsunomiya Y, Yasuda T, Nakabayashi K, Sato T, Onodera M. Functional Domains of ZFP809 Essential for Nuclear Localization and Gene Silencing. PLoS ONE. 2015;10:e0139274 pubmed publisher
|
| Geng J, Sun X, Wang P, Zhang S, Wang X, Wu H, et al. Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity. Nat Immunol. 2015;16:1142-52 pubmed publisher
|
| Li Z, Hao Q, Luo J, Xiong J, Zhang S, Wang T, et al. USP4 inhibits p53 and NF-κB through deubiquitinating and stabilizing HDAC2. Oncogene. 2016;35:2902-12 pubmed publisher
|
| Desmond P, Muriel J, Markwardt M, Rizzo M, Bloch R. Identification of Small Ankyrin 1 as a Novel Sarco(endo)plasmic Reticulum Ca2+-ATPase 1 (SERCA1) Regulatory Protein in Skeletal Muscle. J Biol Chem. 2015;290:27854-67 pubmed publisher
|
| Bi H, Li S, Qu X, Wang M, Bai X, Xu Z, et al. DEC1 regulates breast cancer cell proliferation by stabilizing cyclin E protein and delays the progression of cell cycle S phase. Cell Death Dis. 2015;6:e1891 pubmed publisher
|
| Heusinger E, Kluge S, Kirchhoff F, Sauter D. Early Vertebrate Evolution of the Host Restriction Factor Tetherin. J Virol. 2015;89:12154-65 pubmed publisher
|
| Werner A, Iwasaki S, McGourty C, Medina Ruiz S, Teerikorpi N, Fedrigo I, et al. Cell-fate determination by ubiquitin-dependent regulation of translation. Nature. 2015;525:523-7 pubmed publisher
|
| Zhan Y, Kost Alimova M, Shi X, Leo E, Bardenhagen J, Shepard H, et al. Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery. Epigenetics Chromatin. 2015;8:37 pubmed publisher
|
| Vandersmissen I, Craps S, Depypere M, Coppiello G, van Gastel N, Maes F, et al. Endothelial Msx1 transduces hemodynamic changes into an arteriogenic remodeling response. J Cell Biol. 2015;210:1239-56 pubmed publisher
|
| Schmoller K, Turner J, Kõivomägi M, Skotheim J. Dilution of the cell cycle inhibitor Whi5 controls budding-yeast cell size. Nature. 2015;526:268-72 pubmed publisher
|
| Julian M, Lee C, Tiller K, Rabia L, Day E, Schick A, et al. Co-evolution of affinity and stability of grafted amyloid-motif domain antibodies. Protein Eng Des Sel. 2015;28:339-50 pubmed publisher
|
| Zhu L, Wang Z, Wang W, Wang C, Hua S, Su Z, et al. Mitotic Protein CSPP1 Interacts with CENP-H Protein to Coordinate Accurate Chromosome Oscillation in Mitosis. J Biol Chem. 2015;290:27053-66 pubmed publisher
|
| Civiero L, Cirnaru M, Beilina A, Rodella U, Russo I, Belluzzi E, et al. Leucine-rich repeat kinase 2 interacts with p21-activated kinase 6 to control neurite complexity in mammalian brain. J Neurochem. 2015;135:1242-56 pubmed publisher
|
| Baker C, Petkova P, Walker M, Flachs P, Mihola O, Trachtulec Z, et al. Multimer Formation Explains Allelic Suppression of PRDM9 Recombination Hotspots. PLoS Genet. 2015;11:e1005512 pubmed publisher
|
| Xiao X, Shi X, Fan Y, Zhang X, Wu M, Lan P, et al. GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation. Nat Commun. 2015;6:8266 pubmed publisher
|
| Choi I, Kim B, Byun J, Baik S, Huh Y, Kim J, et al. LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase. Nat Commun. 2015;6:8255 pubmed publisher
|
| Wu S, Kao C, Wang L, Creighton C, Yang J, Donti T, et al. Increased COUP-TFII expression in adult hearts induces mitochondrial dysfunction resulting in heart failure. Nat Commun. 2015;6:8245 pubmed publisher
|
| Savic D, Partridge E, Newberry K, Smith S, Meadows S, Roberts B, et al. CETCh-seq: CRISPR epitope tagging ChIP-seq of DNA-binding proteins. Genome Res. 2015;25:1581-9 pubmed publisher
|
| Moser B, Raguimova O, Nakamura T. Ccq1-Tpz1TPP1 interaction facilitates telomerase and SHREC association with telomeres in fission yeast. Mol Biol Cell. 2015;26:3857-66 pubmed publisher
|
| Brietzke A, Arnemo M, Gjøen T, Rebl H, Korytář T, Goldammer T, et al. Structurally diverse genes encode Tlr2 in rainbow trout: The conserved receptor cannot be stimulated by classical ligands to activate NF-κB in vitro. Dev Comp Immunol. 2016;54:75-88 pubmed publisher
|
| Plescher M, Teleman A, Demetriades C. TSC2 mediates hyperosmotic stress-induced inactivation of mTORC1. Sci Rep. 2015;5:13828 pubmed publisher
|
| Ebert S, Dyle M, Bullard S, Dierdorff J, Murry D, Fox D, et al. Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 (ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy. J Biol Chem. 2015;290:25497-511 pubmed publisher
|
| Strnadova P, Ren H, Valentine R, Mazzon M, Sweeney T, Brierley I, et al. Inhibition of Translation Initiation by Protein 169: A Vaccinia Virus Strategy to Suppress Innate and Adaptive Immunity and Alter Virus Virulence. PLoS Pathog. 2015;11:e1005151 pubmed publisher
|
| Moreno Mateos M, Vejnar C, Beaudoin J, Fernandez J, Mis E, Khokha M, et al. CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo. Nat Methods. 2015;12:982-8 pubmed publisher
|
| Qiu D, Ye S, Ruiz B, Zhou X, Liu D, Zhang Q, et al. Klf2 and Tfcp2l1, Two Wnt/β-Catenin Targets, Act Synergistically to Induce and Maintain Naive Pluripotency. Stem Cell Reports. 2015;5:314-22 pubmed publisher
|
| Hasan M, Fermaintt C, Gao N, Sakai T, Miyazaki T, Jiang S, et al. Cytosolic Nuclease TREX1 Regulates Oligosaccharyltransferase Activity Independent of Nuclease Activity to Suppress Immune Activation. Immunity. 2015;43:463-74 pubmed publisher
|
| Zhou N, Yuan S, Wang R, Zhang W, Chen J. Role of dual specificity tyrosine-phosphorylation-regulated kinase 1B (Dyrk1B) in S-phase entry of HPV E7 expressing cells from quiescence. Oncotarget. 2015;6:30745-61 pubmed publisher
|
| Franceschi V, Capocefalo A, Jacca S, Rosamilia A, Cavirani S, Xu F, et al. BoHV-4 immediate early 1 gene is a dispensable gene and its product is not a bone marrow stromal cell antigen 2 counteracting factor. BMC Vet Res. 2015;11:224 pubmed publisher
|
| Schweitzer L, Comb W, Bar Peled L, Sabatini D. Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1. Cell Rep. 2015;12:1445-55 pubmed publisher
|
| Nishi Y, Zhang X, Jeong J, Peterson K, Vedenko A, Bulyk M, et al. A direct fate exclusion mechanism by Sonic hedgehog-regulated transcriptional repressors. Development. 2015;142:3286-93 pubmed publisher
|
| Park E, Kim N, Ficarro S, Zhang Y, Lee B, Cho A, et al. Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6. Nat Struct Mol Biol. 2015;22:703-711 pubmed publisher
|
| Kruiswijk F, Hasenfuss S, Sivapatham R, Baar M, Putavet D, Naipal K, et al. Targeted inhibition of metastatic melanoma through interference with Pin1-FOXM1 signaling. Oncogene. 2016;35:2166-77 pubmed publisher
|
| Iansante V, Choy P, Fung S, Liu Y, Chai J, Dyson J, et al. PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation. Nat Commun. 2015;6:7882 pubmed publisher
|
| Reinoso Colacio M, GarcÃa RodrÃguez F, GarcÃa Cañadas M, Amador Cubero S, GarcÃa Pérez J, Toro N. Localization of a bacterial group II intron-encoded protein in human cells. Sci Rep. 2015;5:12716 pubmed publisher
|
| Vuong L, Chellappa K, Dhahbi J, Deans J, Fang B, Bolotin E, et al. Differential Effects of Hepatocyte Nuclear Factor 4α Isoforms on Tumor Growth and T-Cell Factor 4/AP-1 Interactions in Human Colorectal Cancer Cells. Mol Cell Biol. 2015;35:3471-90 pubmed publisher
|
| Fu J, Bian M, Xin G, Deng Z, Luo J, Guo X, et al. TPX2 phosphorylation maintains metaphase spindle length by regulating microtubule flux. J Cell Biol. 2015;210:373-83 pubmed publisher
|
| Fisher O, Deng H, Liu D, Zhang Y, Wei R, Deng Y, et al. Structure and vascular function of MEKK3-cerebral cavernous malformations 2 complex. Nat Commun. 2015;6:7937 pubmed publisher
|
| Ohsawa Y, Takayama K, Nishimatsu S, Okada T, Fujino M, Fukai Y, et al. The Inhibitory Core of the Myostatin Prodomain: Its Interaction with Both Type I and II Membrane Receptors, and Potential to Treat Muscle Atrophy. PLoS ONE. 2015;10:e0133713 pubmed publisher
|
| Chen C, Tian F, Lu L, Wang Y, Xiao Z, Yu C, et al. Characterization of Cep85 - a new antagonist of Nek2A that is involved in the regulation of centrosome disjunction. J Cell Sci. 2015;128:3290-303 pubmed publisher
|
| Kimoto C, Moriyama T, Tsujii A, Igarashi Y, Obuse C, Miyamoto Y, et al. Functional characterization of importin α8 as a classical nuclear localization signal receptor. Biochim Biophys Acta. 2015;1853:2676-83 pubmed publisher
|
| Tomita T, Hamazaki J, Hirayama S, McBurney M, Yashiroda H, Murata S. Sirt1-deficiency causes defective protein quality control. Sci Rep. 2015;5:12613 pubmed publisher
|
| Lee K, Im J, Shibata E, Park J, Handa N, Kowalczykowski S, et al. MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex. Nat Commun. 2015;6:7744 pubmed publisher
|
| Lefèvre L, Omeiri H, Drougat L, Hantel C, Giraud M, Val P, et al. Combined transcriptome studies identify AFF3 as a mediator of the oncogenic effects of β-catenin in adrenocortical carcinoma. Oncogenesis. 2015;4:e161 pubmed publisher
|
| Brichta L, Shin W, Jackson Lewis V, Blesa J, Yap E, Walker Z, et al. Identification of neurodegenerative factors using translatome-regulatory network analysis. Nat Neurosci. 2015;18:1325-33 pubmed publisher
|
| Mizuhashi K, Chaya T, Kanamoto T, Omori Y, Furukawa T. Obif, a Transmembrane Protein, Is Required for Bone Mineralization and Spermatogenesis in Mice. PLoS ONE. 2015;10:e0133704 pubmed publisher
|
| Latos P, Goncalves A, Oxley D, Mohammed H, Turro E, Hemberger M. Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells. Nat Commun. 2015;6:7776 pubmed publisher
|
| Zhu C, Chen C, Huang J, Zhang H, Zhao X, Deng R, et al. SUMOylation at K707 of DGCR8 controls direct function of primary microRNA. Nucleic Acids Res. 2015;43:7945-60 pubmed publisher
|
| Nyathi Y, Pool M. Analysis of the interplay of protein biogenesis factors at the ribosome exit site reveals new role for NAC. J Cell Biol. 2015;210:287-301 pubmed publisher
|
| Masuda Y, Kanao R, Kaji K, Ohmori H, Hanaoka F, Masutani C. Different types of interaction between PCNA and PIP boxes contribute to distinct cellular functions of Y-family DNA polymerases. Nucleic Acids Res. 2015;43:7898-910 pubmed publisher
|
| Murakawa Y, Hinz M, Mothes J, Schuetz A, Uhl M, Wyler E, et al. RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway. Nat Commun. 2015;6:7367 pubmed publisher
|
| Cao X, Kaneko T, Li J, Liu A, Voss C, Li S. A phosphorylation switch controls the spatiotemporal activation of Rho GTPases in directional cell migration. Nat Commun. 2015;6:7721 pubmed publisher
|
| Scarola M, Comisso E, Pascolo R, Chiaradia R, Marión R, Schneider C, et al. Epigenetic silencing of Oct4 by a complex containing SUV39H1 and Oct4 pseudogene lncRNA. Nat Commun. 2015;6:7631 pubmed publisher
|
| Meyer R, Chuong H, Hild M, Hansen C, Kinter M, Dawson D. Ipl1/Aurora-B is necessary for kinetochore restructuring in meiosis I in Saccharomyces cerevisiae. Mol Biol Cell. 2015;26:2986-3000 pubmed publisher
|
| Gallmetzer A, Silvestrini L, Schinko T, Gesslbauer B, Hortschansky P, Dattenböck C, et al. Reversible Oxidation of a Conserved Methionine in the Nuclear Export Sequence Determines Subcellular Distribution and Activity of the Fungal Nitrate Regulator NirA. PLoS Genet. 2015;11:e1005297 pubmed publisher
|
| Katoh T, Hojo H, Suzuki T. Destabilization of microRNAs in human cells by 3' deadenylation mediated by PARN and CUGBP1. Nucleic Acids Res. 2015;43:7521-34 pubmed publisher
|
| Cho H, Kang J, Lee J, Lee J, Jeon S, Ko J, et al. Direct regulation of E-cadherin by targeted histone methylation of TALE-SET fusion protein in cancer cells. Oncotarget. 2015;6:23837-44 pubmed
|
| Zhu S, Chen Z, Katsha A, Hong J, Belkhiri A, el Rifai W. Regulation of CD44E by DARPP-32-dependent activation of SRp20 splicing factor in gastric tumorigenesis. Oncogene. 2016;35:1847-56 pubmed publisher
|
| Romano S, Xiao Y, Nakaya M, D Angelillo A, Chang M, Jin J, et al. FKBP51 employs both scaffold and isomerase functions to promote NF-κB activation in melanoma. Nucleic Acids Res. 2015;43:6983-93 pubmed publisher
|
| Moyer T, Clutario K, Lambrus B, Daggubati V, Holland A. Binding of STIL to Plk4 activates kinase activity to promote centriole assembly. J Cell Biol. 2015;209:863-78 pubmed publisher
|
| Ibeawuchi S, Agbor L, Quelle F, Sigmund C. Hypertension-causing Mutations in Cullin3 Protein Impair RhoA Protein Ubiquitination and Augment the Association with Substrate Adaptors. J Biol Chem. 2015;290:19208-17 pubmed publisher
|
| Wang N, Zhang L, Chen Y, Lu Z, Gao L, Wang Y, et al. Cyclophilin A Interacts with Viral VP4 and Inhibits the Replication of Infectious Bursal Disease Virus. Biomed Res Int. 2015;2015:719454 pubmed publisher
|
| Westhorpe F, Fuller C, Straight A. A cell-free CENP-A assembly system defines the chromatin requirements for centromere maintenance. J Cell Biol. 2015;209:789-801 pubmed publisher
|
| Cha Molstad H, Sung K, Hwang J, Kim K, Yu J, Yoo Y, et al. Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding. Nat Cell Biol. 2015;17:917-29 pubmed publisher
|
| Bock F, Tanzer M, Haschka M, Krumschnabel G, Sohm B, Goetsch K, et al. The p53 binding protein PDCD5 is not rate-limiting in DNA damage induced cell death. Sci Rep. 2015;5:11268 pubmed publisher
|
| Xu Y, Wu X, Her C. hMSH5 Facilitates the Repair of Camptothecin-induced Double-strand Breaks through an Interaction with FANCJ. J Biol Chem. 2015;290:18545-58 pubmed publisher
|
| Neo S, Itahana Y, Alagu J, Kitagawa M, Guo A, Lee S, et al. TRIM28 Is an E3 Ligase for ARF-Mediated NPM1/B23 SUMOylation That Represses Centrosome Amplification. Mol Cell Biol. 2015;35:2851-63 pubmed publisher
|
| Vanhollebeke B, Stone O, Bostaille N, Cho C, Zhou Y, Maquet E, et al. Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis. elife. 2015;4: pubmed publisher
|
| Chen C, Wu M, Huang Y, Lin P, Shih C, Lin F, et al. Iridovirus CARD Protein Inhibits Apoptosis through Intrinsic and Extrinsic Pathways. PLoS ONE. 2015;10:e0129071 pubmed publisher
|
| Schock E, Chang C, Struve J, Chang Y, Chang J, Delany M, et al. Using the avian mutant talpid2 as a disease model for understanding the oral-facial phenotypes of oral-facial-digital syndrome. Dis Model Mech. 2015;8:855-66 pubmed publisher
|
| Casey A, Chen S, Novick P, Ferro Novick S, Wente S. Nuclear pore complex integrity requires Lnp1, a regulator of cortical endoplasmic reticulum. Mol Biol Cell. 2015;26:2833-44 pubmed publisher
|
| Cheedipudi S, Puri D, Saleh A, Gala H, Rumman M, Pillai M, et al. A fine balance: epigenetic control of cellular quiescence by the tumor suppressor PRDM2/RIZ at a bivalent domain in the cyclin a gene. Nucleic Acids Res. 2015;43:6236-56 pubmed publisher
|
| Abdelhamed Z, Natarajan S, Wheway G, Inglehearn C, Toomes C, Johnson C, et al. The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway. Dis Model Mech. 2015;8:527-41 pubmed publisher
|
| Koenig J, Werdehausen R, Linley J, Habib A, Vernon J, Lolignier S, et al. Regulation of Nav1.7: A Conserved SCN9A Natural Antisense Transcript Expressed in Dorsal Root Ganglia. PLoS ONE. 2015;10:e0128830 pubmed publisher
|
| Urban B, Collard T, Eagle C, Southern S, Greenhough A, Hamdollah Zadeh M, et al. BCL-3 expression promotes colorectal tumorigenesis through activation of AKT signalling. Gut. 2016;65:1151-64 pubmed publisher
|
| Yeh J, Kreimer S, Walker S, Emori M, Krystal H, Richardson A, et al. Granulin, a novel STAT3-interacting protein, enhances STAT3 transcriptional function and correlates with poorer prognosis in breast cancer. Genes Cancer. 2015;6:153-68 pubmed
|
| Peng B, Wang J, Hu Y, Zhao H, Hou W, Zhao H, et al. Modulation of LSD1 phosphorylation by CK2/WIP1 regulates RNF168-dependent 53BP1 recruitment in response to DNA damage. Nucleic Acids Res. 2015;43:5936-47 pubmed publisher
|
| Milkereit R, Persaud A, Vanoaica L, Guetg A, Verrey F, Rotin D. LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation. Nat Commun. 2015;6:7250 pubmed publisher
|
| Choi S, Lim D, Chung J. Feeding and Fasting Signals Converge on the LKB1-SIK3 Pathway to Regulate Lipid Metabolism in Drosophila. PLoS Genet. 2015;11:e1005263 pubmed publisher
|
| Feng X, Li Z, Du Y, Fu H, Klein J, Cai H, et al. Downregulation of urea transporter UT-A1 activity by 14-3-3 protein. Am J Physiol Renal Physiol. 2015;309:F71-8 pubmed publisher
|
| Zhang J, Siew K, MacArtney T, O Shaughnessy K, Alessi D. Critical role of the SPAK protein kinase CCT domain in controlling blood pressure. Hum Mol Genet. 2015;24:4545-58 pubmed publisher
|
| Wende C, Zoubaa S, Blak A, Echevarria D, Martinez S, Guillemot F, et al. Hairy/Enhancer-of-Split MEGANE and Proneural MASH1 Factors Cooperate Synergistically in Midbrain GABAergic Neurogenesis. PLoS ONE. 2015;10:e0127681 pubmed publisher
|
| Roe J, Mercan F, Rivera K, Pappin D, Vakoc C. BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia. Mol Cell. 2015;58:1028-39 pubmed publisher
|
| Ahmed S, Bott D, Gomez A, Tamblyn L, Rasheed A, Cho T, et al. Loss of the Mono-ADP-ribosyltransferase, Tiparp, Increases Sensitivity to Dioxin-induced Steatohepatitis and Lethality. J Biol Chem. 2015;290:16824-40 pubmed publisher
|
| Tanas M, Ma S, Jadaan F, Ng C, Weigelt B, Reis Filho J, et al. Mechanism of action of a WWTR1(TAZ)-CAMTA1 fusion oncoprotein. Oncogene. 2016;35:929-38 pubmed publisher
|
| Lee F, Chuang H, Chen N, Nagarajan G, Chiou P. Toll-Like Receptor 9 Alternatively Spliced Isoform Negatively Regulates TLR9 Signaling in Teleost Fish. PLoS ONE. 2015;10:e0126388 pubmed publisher
|
| McCourt J, Rhett K, Jaeger M, Belanto J, Talsness D, Ervasti J. In vitro stability of therapeutically relevant, internally truncated dystrophins. Skelet Muscle. 2015;5:13 pubmed publisher
|
| Casimiro M, Di Sante G, Crosariol M, Loro E, Dampier W, Ertel A, et al. Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis. Oncotarget. 2015;6:8525-38 pubmed
|
| Buonora J, Mousseau M, Jacobowitz D, Lazarus R, Yarnell A, Olsen C, et al. Autoimmune Profiling Reveals Peroxiredoxin 6 as a Candidate Traumatic Brain Injury Biomarker. J Neurotrauma. 2015;32:1805-14 pubmed publisher
|
| Li Q, Wang X, Sun H, Zeng J, Cao Z, Li Y, et al. Regulation of Active DNA Demethylation by a Methyl-CpG-Binding Domain Protein in Arabidopsis thaliana. PLoS Genet. 2015;11:e1005210 pubmed publisher
|
| Wright J, Atwan Z, Morris S, Leppard K. The Human Adenovirus Type 5 L4 Promoter Is Negatively Regulated by TFII-I and L4-33K. J Virol. 2015;89:7053-63 pubmed publisher
|
| Ulke Lemée A, Turner S, MacDonald J. In situ analysis of smoothelin-like 1 and calmodulin interactions in smooth muscle cells by proximity ligation. J Cell Biochem. 2015;116:2667-75 pubmed publisher
|
| Kang X, Lu Z, Cui C, Deng M, Fan Y, Dong B, et al. The ITIM-containing receptor LAIR1 is essential for acute myeloid leukaemia development. Nat Cell Biol. 2015;17:665-77 pubmed publisher
|
| Huang L, Counter C. Reduced HRAS G12V-Driven Tumorigenesis of Cell Lines Expressing KRAS C118S. PLoS ONE. 2015;10:e0123918 pubmed publisher
|
| Deglincerti A, Liu Y, Colak D, Hengst U, Xu G, Jaffrey S. Coupled local translation and degradation regulate growth cone collapse. Nat Commun. 2015;6:6888 pubmed publisher
|
| Liu X, Chen Z, Xu C, Leng X, Cao H, Ouyang G, et al. Repression of hypoxia-inducible factor α signaling by Set7-mediated methylation. Nucleic Acids Res. 2015;43:5081-98 pubmed publisher
|
| Kroeze W, Sassano M, Huang X, Lansu K, McCorvy J, Giguère P, et al. PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome. Nat Struct Mol Biol. 2015;22:362-9 pubmed publisher
|
| Yamana S, Tokiyama A, Mizutani K, Hirata K, Takai Y, Rikitake Y. The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation. PLoS ONE. 2015;10:e0124259 pubmed publisher
|
| Holehonnur R, Lella S, Ho A, Luong J, Ploski J. The production of viral vectors designed to express large and difficult to express transgenes within neurons. Mol Brain. 2015;8:12 pubmed publisher
|
| Sirrs S, van Karnebeek C, Peng X, Shyr C, Tarailo Graovac M, Mandal R, et al. Defects in fatty acid amide hydrolase 2 in a male with neurologic and psychiatric symptoms. Orphanet J Rare Dis. 2015;10:38 pubmed publisher
|
| Świątek Połatyńska M, Bucca G, Laing E, Gubbens J, Titgemeyer F, Smith C, et al. Genome-wide analysis of in vivo binding of the master regulator DasR in Streptomyces coelicolor identifies novel non-canonical targets. PLoS ONE. 2015;10:e0122479 pubmed publisher
|
| Tsai F, Vijayraghavan S, Prinz J, MacAlpine H, MacAlpine D, Schwacha A. Mcm2-7 Is an Active Player in the DNA Replication Checkpoint Signaling Cascade via Proposed Modulation of Its DNA Gate. Mol Cell Biol. 2015;35:2131-43 pubmed publisher
|
| Tanabe H, Fujii Y, Okada Iwabu M, Iwabu M, Nakamura Y, Hosaka T, et al. Crystal structures of the human adiponectin receptors. Nature. 2015;520:312-316 pubmed publisher
|
| Davis K, Pattanayak V, Thompson D, Zuris J, Liu D. Small molecule-triggered Cas9 protein with improved genome-editing specificity. Nat Chem Biol. 2015;11:316-8 pubmed publisher
|
| Comiskey D, Jacob A, Singh R, Tapia Santos A, Chandler D. Splicing factor SRSF1 negatively regulates alternative splicing of MDM2 under damage. Nucleic Acids Res. 2015;43:4202-18 pubmed publisher
|
| Gagnon D, Lehoux M, Archambault J. Artificial Recruitment of UAF1-USP Complexes by a PHLPP1-E1 Chimeric Helicase Enhances Human Papillomavirus DNA Replication. J Virol. 2015;89:6227-39 pubmed publisher
|
| Ma S, Jiang B, Deng W, Gu Z, Wu F, Li T, et al. D-2-hydroxyglutarate is essential for maintaining oncogenic property of mutant IDH-containing cancer cells but dispensable for cell growth. Oncotarget. 2015;6:8606-20 pubmed
|
| Shi Y, Chen J, Karner C, Long F. Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation. Proc Natl Acad Sci U S A. 2015;112:4678-83 pubmed publisher
|
| Tsukiyama T, Fukui A, Terai S, Fujioka Y, Shinada K, Takahashi H, et al. Molecular Role of RNF43 in Canonical and Noncanonical Wnt Signaling. Mol Cell Biol. 2015;35:2007-23 pubmed publisher
|
| Zhao Z, Chen C, Rillahan C, Shen R, Kitzing T, McNerney M, et al. Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis. Nat Genet. 2015;47:539-43 pubmed publisher
|
| Zhang T, Dong K, Liang W, Xu D, Xia H, Geng J, et al. G-protein-coupled receptors regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L. elife. 2015;4:e06734 pubmed publisher
|
| Kim J, Ro S, Kim M, Park H, Semple I, Park H, et al. Sestrin2 inhibits mTORC1 through modulation of GATOR complexes. Sci Rep. 2015;5:9502 pubmed publisher
|
| Xu D, Li C, Zhang X, Gong Z, Chan C, Lee S, et al. Skp2-macroH2A1-CDK8 axis orchestrates G2/M transition and tumorigenesis. Nat Commun. 2015;6:6641 pubmed publisher
|
| Popp M, Maquat L. Attenuation of nonsense-mediated mRNA decay facilitates the response to chemotherapeutics. Nat Commun. 2015;6:6632 pubmed publisher
|
| Wan J, Zhan J, Li S, Ma J, Xu W, Liu C, et al. PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression. Nucleic Acids Res. 2015;43:3591-604 pubmed publisher
|
| Boersma V, Moatti N, Segura Bayona S, Peuscher M, van der Torre J, Wevers B, et al. MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection. Nature. 2015;521:537-540 pubmed publisher
|
| Shrestha S, Sun Y, Lufkin T, Kraus P, Or Y, Garcia Y, et al. Tetratricopeptide repeat domain 9A negatively regulates estrogen receptor alpha activity. Int J Biol Sci. 2015;11:434-47 pubmed publisher
|
| Yang B, Feng L, Wang F, Wang L. Enterohemorrhagic Escherichia coli senses low biotin status in the large intestine for colonization and infection. Nat Commun. 2015;6:6592 pubmed publisher
|
| Mignogna M, Giannandrea M, Gurgone A, Fanelli F, Raimondi F, Mapelli L, et al. The intellectual disability protein RAB39B selectively regulates GluA2 trafficking to determine synaptic AMPAR composition. Nat Commun. 2015;6:6504 pubmed publisher
|
| Yeh C, Kuo P, Wang Y, Wu Y, Chen M, Lin D, et al. SEPT12/SPAG4/LAMINB1 complexes are required for maintaining the integrity of the nuclear envelope in postmeiotic male germ cells. PLoS ONE. 2015;10:e0120722 pubmed publisher
|
| Pinz S, Unser S, Buob D, Fischer P, Jobst B, Rascle A. Deacetylase inhibitors repress STAT5-mediated transcription by interfering with bromodomain and extra-terminal (BET) protein function. Nucleic Acids Res. 2015;43:3524-45 pubmed publisher
|
| Ng C, Akhter A, Yurko N, Burgener J, Rosonina E, Manley J. Sumoylation controls the timing of Tup1-mediated transcriptional deactivation. Nat Commun. 2015;6:6610 pubmed publisher
|
| Jiao H, Xu Y, Li J, Wang W, Mei Z, Long X, et al. Prognostic significance of Cbx4 expression and its beneficial effect for transarterial chemoembolization in hepatocellular carcinoma. Cell Death Dis. 2015;6:e1689 pubmed publisher
|
| Botelho H, Uliyakina I, Awatade N, Proença M, Tischer C, Sirianant L, et al. Protein traffic disorders: an effective high-throughput fluorescence microscopy pipeline for drug discovery. Sci Rep. 2015;5:9038 pubmed publisher
|
| Hodgson A, Wier E, Fu K, Sun X, Yu H, Zheng W, et al. Metalloprotease NleC suppresses host NF-κB/inflammatory responses by cleaving p65 and interfering with the p65/RPS3 interaction. PLoS Pathog. 2015;11:e1004705 pubmed publisher
|
| Rüegger S, Miki T, Hess D, Großhans H. The ribonucleotidyl transferase USIP-1 acts with SART3 to promote U6 snRNA recycling. Nucleic Acids Res. 2015;43:3344-57 pubmed publisher
|
| Chen S, Sanjana N, Zheng K, Shalem O, Lee K, Shi X, et al. Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis. Cell. 2015;160:1246-60 pubmed publisher
|
| Wu J, Pipathsouk A, Keizer Gunnink A, Fusetti F, Alkema W, Liu S, et al. Homer3 regulates the establishment of neutrophil polarity. Mol Biol Cell. 2015;26:1629-39 pubmed publisher
|
| Park S, Jeong J, Park Y, Park K, Lee H, Lee N, et al. Disrupted-in-schizophrenia-1 (DISC1) Regulates Endoplasmic Reticulum Calcium Dynamics. Sci Rep. 2015;5:8694 pubmed publisher
|
| Bindesbøll C, Fan Q, Nørgaard R, MacPherson L, Ruan H, Wu J, et al. Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity. J Lipid Res. 2015;56:771-85 pubmed publisher
|
| Masuda K, Chiyoda T, Sugiyama N, Segura Cabrera A, Kabe Y, Ueki A, et al. LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C. PLoS ONE. 2015;10:e0118662 pubmed publisher
|
| Lim J, Lachenmayer M, Wu S, Liu W, Kundu M, Wang R, et al. Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates. PLoS Genet. 2015;11:e1004987 pubmed publisher
|
| Deml B, Kariminejad A, Borujerdi R, Muheisen S, Reis L, Semina E. Mutations in MAB21L2 result in ocular Coloboma, microcornea and cataracts. PLoS Genet. 2015;11:e1005002 pubmed publisher
|
| Nakahara T, Tanaka K, Ohno S, Egawa N, Yugawa T, Kiyono T. Activation of NF-κB by human papillomavirus 16 E1 limits E1-dependent viral replication through degradation of E1. J Virol. 2015;89:5040-59 pubmed publisher
|
| O Geen H, Henry I, Bhakta M, Meckler J, Segal D. A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture. Nucleic Acids Res. 2015;43:3389-404 pubmed publisher
|
| Srivastava M, Duan G, Kershaw N, Athanasopoulos V, Yeo J, Ose T, et al. Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis. Nat Commun. 2015;6:6253 pubmed publisher
|
| Hsiao H, Hsu T, Liu W, Hsieh W, Chou T, Wu Y, et al. Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T cells in vivo. Nat Commun. 2015;6:6353 pubmed publisher
|
| Wu J, Yang Z, Wang Y, Zheng L, Ye R, Ji Y, et al. Viral-inducible Argonaute18 confers broad-spectrum virus resistance in rice by sequestering a host microRNA. elife. 2015;4: pubmed publisher
|
| Wang Y, Tan B, Mu R, Chang Y, Wu M, Tu H, et al. Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor κB (NF-κB) signaling. J Biol Chem. 2015;290:10395-405 pubmed publisher
|
| Nakajima T, Kitagawa K, Ohhata T, Sakai S, Uchida C, Shibata K, et al. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2. J Biol Chem. 2015;290:10368-81 pubmed publisher
|
| Wang H, Zhang H, Zhang J, Li Y, Zhao B, Feng G, et al. Neuropilin 1 is an entry factor that promotes EBV infection of nasopharyngeal epithelial cells. Nat Commun. 2015;6:6240 pubmed publisher
|
| Boëda B, Etienne Manneville S. Spectrin binding motifs regulate Scribble cortical dynamics and polarity function. elife. 2015;4: pubmed publisher
|
| Brazina J, Svadlenka J, Macurek L, Andera L, Hodny Z, Bartek J, et al. DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase. Cell Cycle. 2015;14:375-87 pubmed publisher
|
| Papadakis A, Sun C, Knijnenburg T, Xue Y, Grernrum W, Hölzel M, et al. SMARCE1 suppresses EGFR expression and controls responses to MET and ALK inhibitors in lung cancer. Cell Res. 2015;25:445-58 pubmed publisher
|
| West A, Khoury Hanold W, Staron M, Tal M, Pineda C, Lang S, et al. Mitochondrial DNA stress primes the antiviral innate immune response. Nature. 2015;520:553-7 pubmed publisher
|
| Kaucká M, Petersen J, Janovská P, Radaszkiewicz T, SmyÄková L, Daulat A, et al. Asymmetry of VANGL2 in migrating lymphocytes as a tool to monitor activity of the mammalian WNT/planar cell polarity pathway. Cell Commun Signal. 2015;13:2 pubmed publisher
|
| Morelli M, Dennis A, Patton J. Putative E3 ubiquitin ligase of human rotavirus inhibits NF-κB activation by using molecular mimicry to target β-TrCP. MBio. 2015;6: pubmed publisher
|
| Mahajan A, Sim X, Ng H, Manning A, Rivas M, Highland H, et al. Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus. PLoS Genet. 2015;11:e1004876 pubmed publisher
|
| Lewis H, Liddle J, Coote J, Atkinson S, Barker M, Bax B, et al. Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation. Nat Chem Biol. 2015;11:189-91 pubmed publisher
|
| Furusawa T, Rochman M, Taher L, Dimitriadis E, Nagashima K, Anderson S, et al. Chromatin decompaction by the nucleosomal binding protein HMGN5 impairs nuclear sturdiness. Nat Commun. 2015;6:6138 pubmed publisher
|
| Jin Z, Chung J, Mei W, Strack S, He C, Lau G, et al. Regulation of nuclear-cytoplasmic shuttling and function of Family with sequence similarity 13, member A (Fam13a), by B56-containing PP2As and Akt. Mol Biol Cell. 2015;26:1160-73 pubmed publisher
|
| Benada J, Burdová K, Lidak T, von Morgen P, Macurek L. Polo-like kinase 1 inhibits DNA damage response during mitosis. Cell Cycle. 2015;14:219-31 pubmed publisher
|
| Suzuki K, Sako K, Akiyama K, Isoda M, Senoo C, Nakajo N, et al. Identification of non-Ser/Thr-Pro consensus motifs for Cdk1 and their roles in mitotic regulation of C2H2 zinc finger proteins and Ect2. Sci Rep. 2015;5:7929 pubmed publisher
|
| Lu W, Liu S, Li B, Xie Y, Adhiambo C, Yang Q, et al. SKP2 inactivation suppresses prostate tumorigenesis by mediating JARID1B ubiquitination. Oncotarget. 2015;6:771-88 pubmed
|
| Rajakylä E, Viita T, Kyheröinen S, Huet G, Treisman R, Vartiainen M. RNA export factor Ddx19 is required for nuclear import of the SRF coactivator MKL1. Nat Commun. 2015;6:5978 pubmed publisher
|
| Ogo O, Tyson J, Cockell S, Howard A, Valentine R, Ford D. The zinc finger protein ZNF658 regulates the transcription of genes involved in zinc homeostasis and affects ribosome biogenesis through the zinc transcriptional regulatory element. Mol Cell Biol. 2015;35:977-87 pubmed publisher
|
| Minch K, Rustad T, Peterson E, Winkler J, Reiss D, Ma S, et al. The DNA-binding network of Mycobacterium tuberculosis. Nat Commun. 2015;6:5829 pubmed publisher
|
| Andres S, Appel C, Westmoreland J, Williams J, Nguyen Y, Robertson P, et al. Tetrameric Ctp1 coordinates DNA binding and DNA bridging in DNA double-strand-break repair. Nat Struct Mol Biol. 2015;22:158-66 pubmed publisher
|
| Ren J, Briones V, Barbour S, Yu W, Han Y, Terashima M, et al. The ATP binding site of the chromatin remodeling homolog Lsh is required for nucleosome density and de novo DNA methylation at repeat sequences. Nucleic Acids Res. 2015;43:1444-55 pubmed publisher
|
| Rowe C, Chen J, Jardetzky T, Longnecker R. Membrane anchoring of Epstein-Barr virus gp42 inhibits fusion with B cells even with increased flexibility allowed by engineered spacers. MBio. 2015;6: pubmed publisher
|
| Sagata D, Minagawa I, Kohriki H, Pitia A, Uera N, Katakura Y, et al. The insulin-like factor 3 (INSL3)-receptor (RXFP2) network functions as a germ cell survival/anti-apoptotic factor in boar testes. Endocrinology. 2015;156:1523-39 pubmed publisher
|
| Belman J, Bian R, Habtemichael E, Li D, Jurczak M, Alcazar Roman A, et al. Acetylation of TUG protein promotes the accumulation of GLUT4 glucose transporters in an insulin-responsive intracellular compartment. J Biol Chem. 2015;290:4447-63 pubmed publisher
|
| Earley L, Kawano Y, Adachi K, Sun X, Dai M, Nakai H. Identification and characterization of nuclear and nucleolar localization signals in the adeno-associated virus serotype 2 assembly-activating protein. J Virol. 2015;89:3038-48 pubmed publisher
|
| Tange S, Oktyabri D, Terashima M, Ishimura A, Suzuki T. JARID2 is involved in transforming growth factor-beta-induced epithelial-mesenchymal transition of lung and colon cancer cell lines. PLoS ONE. 2014;9:e115684 pubmed publisher
|
| Chae H, Mitton B, Lacayo N, Sakamoto K. Replication factor C3 is a CREB target gene that regulates cell cycle progression through the modulation of chromatin loading of PCNA. Leukemia. 2015;29:1379-89 pubmed publisher
|
| Harmeyer K, South P, Bishop B, Ogas J, Briggs S. Immediate chromatin immunoprecipitation and on-bead quantitative PCR analysis: a versatile and rapid ChIP procedure. Nucleic Acids Res. 2015;43:e38 pubmed publisher
|
| Hamm D, Bondra E, Harrison M. Transcriptional activation is a conserved feature of the early embryonic factor Zelda that requires a cluster of four zinc fingers for DNA binding and a low-complexity activation domain. J Biol Chem. 2015;290:3508-18 pubmed publisher
|
| Wang F, Long Q, Gong Y, Hu L, Zhang H, Oettgen P, et al. Epithelium-Specific ETS (ESE)-1 upregulated GP73 expression in hepatocellular carcinoma cells. Cell Biosci. 2014;4:76 pubmed publisher
|
| Hoffmann F, Kuhn P, Laurent S, Hauck S, Berer K, Wendlinger S, et al. The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity. J Immunol. 2015;194:542-52 pubmed publisher
|
| Hagelueken G, Clarke B, Huang H, Tuukkanen A, Danciu I, Svergun D, et al. A coiled-coil domain acts as a molecular ruler to regulate O-antigen chain length in lipopolysaccharide. Nat Struct Mol Biol. 2015;22:50-56 pubmed publisher
|
| Lin J, Eggensperger S, Hank S, Wycisk A, Wieneke R, Mayerhofer P, et al. A negative feedback modulator of antigen processing evolved from a frameshift in the cowpox virus genome. PLoS Pathog. 2014;10:e1004554 pubmed publisher
|
| Aries A, Whitcomb J, Shao W, Komati H, Saleh M, Nemer M. Caspase-1 cleavage of transcription factor GATA4 and regulation of cardiac cell fate. Cell Death Dis. 2014;5:e1566 pubmed publisher
|
| Chia R, Haddock S, Beilina A, Rudenko I, Mamais A, Kaganovich A, et al. Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7. Nat Commun. 2014;5:5827 pubmed publisher
|
| Paquet N, Box J, Ashton N, Suraweera A, Croft L, Urquhart A, et al. Néstor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutation. BMC Mol Biol. 2014;15:27 pubmed publisher
|
| Castonguay E, White S, Kagansky A, St Cyr D, Castillo A, Brugger C, et al. Panspecies small-molecule disruptors of heterochromatin-mediated transcriptional gene silencing. Mol Cell Biol. 2015;35:662-74 pubmed publisher
|
| Lee M, Venkitaraman A. A cancer-associated mutation inactivates a region of the high-mobility group protein HMG20b essential for cytokinesis. Cell Cycle. 2014;13:2554-63 pubmed publisher
|
| Yokoi N, Fukata Y, Kase D, Miyazaki T, Jaegle M, Ohkawa T, et al. Chemical corrector treatment ameliorates increased seizure susceptibility in a mouse model of familial epilepsy. Nat Med. 2015;21:19-26 pubmed publisher
|
| Morano M, Wrobel S, Fregnan F, Ziv Polat O, Shahar A, Ratzka A, et al. Nanotechnology versus stem cell engineering: in vitro comparison of neurite inductive potentials. Int J Nanomedicine. 2014;9:5289-306 pubmed publisher
|
| Kang H, Yi Y, Hong Y, Kim H, Jang Y, Seong Y, et al. HER2 confers drug resistance of human breast cancer cells through activation of NRF2 by direct interaction. Sci Rep. 2014;4:7201 pubmed publisher
|
| Xu M, Zhu C, Zhao X, Chen C, Zhang H, Yuan H, et al. Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors. Oncotarget. 2015;6:979-94 pubmed
|
| Colbert P, Vermeer D, Wieking B, Lee J, Vermeer P. EphrinB1: novel microtubule associated protein whose expression affects taxane sensitivity. Oncotarget. 2015;6:953-68 pubmed
|
| Park C, Skarra D, Rivera A, Arriola D, Thackray V. Constitutively active FOXO1 diminishes activin induction of Fshb transcription in immortalized gonadotropes. PLoS ONE. 2014;9:e113839 pubmed publisher
|
| Tripathy S, Weil S, Chen C, Anand P, Vallee R, Gross S. Autoregulatory mechanism for dynactin control of processive and diffusive dynein transport. Nat Cell Biol. 2014;16:1192-201 pubmed publisher
|
| Chang S, Chang W, Lu C, Tarn W. Alanine repeats influence protein localization in splicing speckles and paraspeckles. Nucleic Acids Res. 2014;42:13788-98 pubmed publisher
|
| Zhao X, Yang Y, Sun B, Shi Y, Yang X, Xiao W, et al. FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis. Cell Res. 2014;24:1403-19 pubmed publisher
|
| Chen D, Wu C, Zhao S, Geng Q, Gao Y, Li X, et al. Three RNA binding proteins form a complex to promote differentiation of germline stem cell lineage in Drosophila. PLoS Genet. 2014;10:e1004797 pubmed publisher
|
| Wang N, Wang M, Zhu Y, Grosel T, Sun D, Kudryashov D, et al. The Rho-GEF Gef3 interacts with the septin complex and activates the GTPase Rho4 during fission yeast cytokinesis. Mol Biol Cell. 2015;26:238-55 pubmed publisher
|
| Park J, Lee S, Yang S, Yoo H, Park J, Seong M, et al. Modification of DBC1 by SUMO2/3 is crucial for p53-mediated apoptosis in response to DNA damage. Nat Commun. 2014;5:5483 pubmed publisher
|
| Kitamura A, Sasaki Y, Abe T, Kano H, Yasutomo K. An inherited mutation in NLRC4 causes autoinflammation in human and mice. J Exp Med. 2014;211:2385-96 pubmed publisher
|
| Jung K, Wang P, Gupta N, Gopal K, Wu F, Ye X, et al. Profiling gene promoter occupancy of Sox2 in two phenotypically distinct breast cancer cell subsets using chromatin immunoprecipitation and genome-wide promoter microarrays. Breast Cancer Res. 2014;16:470 pubmed publisher
|
| Kranc K, Oliveira D, Armesilla Diaz A, Pacheco Leyva I, Catarina Matias A, Luisa Escapa A, et al. Acute loss of Cited2 impairs Nanog expression and decreases self-renewal of mouse embryonic stem cells. Stem Cells. 2015;33:699-712 pubmed publisher
|
| Sartagul W, Zhou X, Yamada Y, Ma N, Tanaka K, Furuyashiki T, et al. The MluI cell cycle box (MCB) motifs, but not damage-responsive elements (DREs), are responsible for the transcriptional induction of the rhp51+ gene in response to DNA replication stress. PLoS ONE. 2014;9:e111936 pubmed publisher
|
| Zhou Y, Liu X, Engstrom E, NIMCHUK Z, Pruneda Paz J, Tarr P, et al. Control of plant stem cell function by conserved interacting transcriptional regulators. Nature. 2015;517:377-80 pubmed publisher
|
| Bhujbal S, de Haan B, Niclou S, De Vos P. A novel multilayer immunoisolating encapsulation system overcoming protrusion of cells. Sci Rep. 2014;4:6856 pubmed publisher
|
| Khattar V, Thottassery J. Cks1 proteasomal turnover is a predominant mode of regulation in breast cancer cells: role of key tyrosines and lysines. Int J Oncol. 2015;46:395-406 pubmed publisher
|
| Xiao Q, Tan Y, Guo Y, Yang H, Mao F, Xie R, et al. Soluble LRIG2 ectodomain is released from glioblastoma cells and promotes the proliferation and inhibits the apoptosis of glioblastoma cells in vitro and in vivo in a similar manner to the full-length LRIG2. PLoS ONE. 2014;9:e111419 pubmed publisher
|
| Han B, Wu S, Foo C, Horton R, Jenne C, Watson S, et al. Zinc finger protein Zfp335 is required for the formation of the naïve T cell compartment. elife. 2014;3: pubmed publisher
|
| Ohta M, Ashikawa T, Nozaki Y, Kozuka Hata H, Goto H, Inagaki M, et al. Direct interaction of Plk4 with STIL ensures formation of a single procentriole per parental centriole. Nat Commun. 2014;5:5267 pubmed publisher
|
| Choi Y, Harhaj E. HTLV-1 tax stabilizes MCL-1 via TRAF6-dependent K63-linked polyubiquitination to promote cell survival and transformation. PLoS Pathog. 2014;10:e1004458 pubmed publisher
|
| Sanchez Rivera F, Papagiannakopoulos T, Romero R, Tammela T, Bauer M, Bhutkar A, et al. Rapid modelling of cooperating genetic events in cancer through somatic genome editing. Nature. 2014;516:428-31 pubmed publisher
|
| Dikopoltsev E, Foltyn V, Zehl M, Jensen O, Mori H, Radzishevsky I, et al. FBXO22 protein is required for optimal synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine. J Biol Chem. 2014;289:33904-15 pubmed publisher
|
| Wanichawan P, Hafver T, Hodne K, Aronsen J, Lunde I, Dalhus B, et al. Molecular basis of calpain cleavage and inactivation of the sodium-calcium exchanger 1 in heart failure. J Biol Chem. 2014;289:33984-98 pubmed publisher
|
| Fujii H, Tamamori Adachi M, Uchida K, Susa T, Nakakura T, Hagiwara H, et al. Marked cortisol production by intracrine ACTH in GIP-treated cultured adrenal cells in which the GIP receptor was exogenously introduced. PLoS ONE. 2014;9:e110543 pubmed publisher
|
| Harland J, Chang Y, Moser B, Nakamura T. Tpz1-Ccq1 and Tpz1-Poz1 interactions within fission yeast shelterin modulate Ccq1 Thr93 phosphorylation and telomerase recruitment. PLoS Genet. 2014;10:e1004708 pubmed publisher
|
| Wang D, Zhang P, Gao K, Tang Y, Jin X, Zhang Y, et al. PLK1 and β-TrCP-dependent ubiquitination and degradation of Rap1GAP controls cell proliferation. PLoS ONE. 2014;9:e110296 pubmed publisher
|
| Jeppsson K, Carlborg K, Nakato R, Berta D, Lilienthal I, Kanno T, et al. The chromosomal association of the Smc5/6 complex depends on cohesion and predicts the level of sister chromatid entanglement. PLoS Genet. 2014;10:e1004680 pubmed publisher
|
| Zhu M, Zhao H, Liao J, Xu X. HERC2/USP20 coordinates CHK1 activation by modulating CLASPIN stability. Nucleic Acids Res. 2014;42:13074-81 pubmed publisher
|
| Wan Z, Chen X. Triptolide inhibits human immunodeficiency virus type 1 replication by promoting proteasomal degradation of Tat protein. Retrovirology. 2014;11:88 pubmed publisher
|
| Munoz I, Szyniarowski P, Toth R, Rouse J, Lachaud C. Improved genome editing in human cell lines using the CRISPR method. PLoS ONE. 2014;9:e109752 pubmed publisher
|
| Antonelli R, Pizzarelli R, Pedroni A, Fritschy J, Del Sal G, Cherubini E, et al. Pin1-dependent signalling negatively affects GABAergic transmission by modulating neuroligin2/gephyrin interaction. Nat Commun. 2014;5:5066 pubmed publisher
|
| Raman N, Nayak A, Muller S. mTOR signaling regulates nucleolar targeting of the SUMO-specific isopeptidase SENP3. Mol Cell Biol. 2014;34:4474-84 pubmed publisher
|
| Cencic R, Miura H, Malina A, Robert F, Ethier S, Schmeing T, et al. Protospacer adjacent motif (PAM)-distal sequences engage CRISPR Cas9 DNA target cleavage. PLoS ONE. 2014;9:e109213 pubmed publisher
|
| Bayne E, Bijos D, White S, de Lima Alves F, Rappsilber J, Allshire R. A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeast. Genome Biol. 2014;15:481 pubmed
|
| Giguère P, Gall B, Ezekwe E, Laroche G, Buckley B, Kebaier C, et al. G Protein signaling modulator-3 inhibits the inflammasome activity of NLRP3. J Biol Chem. 2014;289:33245-57 pubmed publisher
|
| Peng M, Yin N, Li M. Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling. Cell. 2014;159:122-133 pubmed publisher
|
| Rodrigues Campos M, Thompson B. The ubiquitin ligase FbxL7 regulates the Dachsous-Fat-Dachs system in Drosophila. Development. 2014;141:4098-103 pubmed publisher
|
| Chen Z, Liu B, Tang N, Xu Y, Ye X, Li Z, et al. FBXL5-mediated degradation of single-stranded DNA-binding protein hSSB1 controls DNA damage response. Nucleic Acids Res. 2014;42:11560-9 pubmed publisher
|
| Paix A, Wang Y, Smith H, Lee C, Calidas D, Lu T, et al. Scalable and versatile genome editing using linear DNAs with microhomology to Cas9 Sites in Caenorhabditis elegans. Genetics. 2014;198:1347-56 pubmed publisher
|
| Chang Y, Huang Y. Arsenite-activated JNK signaling enhances CPEB4-Vinexin interaction to facilitate stress granule assembly and cell survival. PLoS ONE. 2014;9:e107961 pubmed publisher
|
| Patel D, Dubash A, Kreitzer G, Green K. Disease mutations in desmoplakin inhibit Cx43 membrane targeting mediated by desmoplakin-EB1 interactions. J Cell Biol. 2014;206:779-97 pubmed publisher
|
| Romberg N, Al Moussawi K, Nelson Williams C, Stiegler A, Loring E, Choi M, et al. Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation. Nat Genet. 2014;46:1135-1139 pubmed publisher
|
| Wei Y. Autophagic induction of amyotrophic lateral sclerosis-linked Cu/Zn superoxide dismutase 1 G93A mutant in NSC34 cells. Neural Regen Res. 2014;9:16-24 pubmed publisher
|
| Trausch Azar J, Abed M, Orian A, Schwartz A. Isoform-specific SCF(Fbw7) ubiquitination mediates differential regulation of PGC-1α. J Cell Physiol. 2015;230:842-52 pubmed publisher
|
| Chen X, Huang H, Wang H, Guo F, Du X, Ma L, et al. Characterization of zebrafish Pax1b and Pax9 in fin bud development. Biomed Res Int. 2014;2014:309385 pubmed publisher
|
| Dubois Chevalier J, Oger F, Dehondt H, Firmin F, Gheeraert C, Staels B, et al. A dynamic CTCF chromatin binding landscape promotes DNA hydroxymethylation and transcriptional induction of adipocyte differentiation. Nucleic Acids Res. 2014;42:10943-59 pubmed publisher
|
| Yang C, Chung A, Ku C, Brill L, Williams R, Wolf D. Systems analysis of the prostate tumor suppressor NKX3.1 supports roles in DNA repair and luminal cell differentiation. F1000Res. 2014;3:115 pubmed publisher
|
| Kuang Z, Cai L, Zhang X, Ji H, Tu B, Boeke J. High-temporal-resolution view of transcription and chromatin states across distinct metabolic states in budding yeast. Nat Struct Mol Biol. 2014;21:854-63 pubmed publisher
|
| Perng Y, Campbell J, Lenschow D, Yu D. Human cytomegalovirus pUL79 is an elongation factor of RNA polymerase II for viral gene transcription. PLoS Pathog. 2014;10:e1004350 pubmed publisher
|
| Ishizuka A, Hasegawa Y, Ishida K, Yanaka K, Nakagawa S. Formation of nuclear bodies by the lncRNA Gomafu-associating proteins Celf3 and SF1. Genes Cells. 2014;19:704-21 pubmed publisher
|
| Han P, Zhou X, Chang N, Xiao C, Yan S, Ren H, et al. Hydrogen peroxide primes heart regeneration with a derepression mechanism. Cell Res. 2014;24:1091-107 pubmed publisher
|
| Budini M, Romano V, Quadri Z, Buratti E, Baralle F. TDP-43 loss of cellular function through aggregation requires additional structural determinants beyond its C-terminal Q/N prion-like domain. Hum Mol Genet. 2015;24:9-20 pubmed publisher
|
| Tsai Y, Lai C, Lai C, Chang K, Wu K, Tseng S, et al. The role of homeostatic regulation between tumor suppressor DAB2IP and oncogenic Skp2 in prostate cancer growth. Oncotarget. 2014;5:6425-36 pubmed
|
| Sen R, Malik S, Frankland Searby S, Uprety B, Lahudkar S, Bhaumik S. Rrd1p, an RNA polymerase II-specific prolyl isomerase and activator of phosphoprotein phosphatase, promotes transcription independently of rapamycin response. Nucleic Acids Res. 2014;42:9892-907 pubmed publisher
|
| Walia V, Prickett T, Kim J, Gartner J, Lin J, Zhou M, et al. Mutational and functional analysis of the tumor-suppressor PTPRD in human melanoma. Hum Mutat. 2014;35:1301-10 pubmed publisher
|
| Park S, Alfa R, Topper S, Kim G, Kockel L, Kim S. A genetic strategy to measure circulating Drosophila insulin reveals genes regulating insulin production and secretion. PLoS Genet. 2014;10:e1004555 pubmed publisher
|
| Vilar M, Sung T, Chen Z, García Carpio I, Fernandez E, Xu J, et al. Heterodimerization of p45-p75 modulates p75 signaling: structural basis and mechanism of action. PLoS Biol. 2014;12:e1001918 pubmed publisher
|
| Vassilopoulos A, Tominaga Y, Kim H, Lahusen T, Li B, Yu H, et al. WEE1 murine deficiency induces hyper-activation of APC/C and results in genomic instability and carcinogenesis. Oncogene. 2015;34:3023-35 pubmed publisher
|
| Tsunoda S, Avezov E, Zyryanova A, Konno T, Mendes Silva L, Pinho Melo E, et al. Intact protein folding in the glutathione-depleted endoplasmic reticulum implicates alternative protein thiol reductants. elife. 2014;3:e03421 pubmed publisher
|
| Huang Y, Bulavin D. Oncogene-mediated regulation of p53 ISGylation and functions. Oncotarget. 2014;5:5808-18 pubmed
|
| Zhang W, DeRyckere D, Hunter D, Liu J, Stashko M, Minson K, et al. UNC2025, a potent and orally bioavailable MER/FLT3 dual inhibitor. J Med Chem. 2014;57:7031-41 pubmed publisher
|
| Chang C, Schock E, O Hare E, Dodgson J, Cheng H, Muir W, et al. The cellular and molecular etiology of the craniofacial defects in the avian ciliopathic mutant talpid2. Development. 2014;141:3003-12 pubmed publisher
|
| Fujita T, Fujii H. Identification of proteins associated with an IFN?-responsive promoter by a retroviral expression system for enChIP using CRISPR. PLoS ONE. 2014;9:e103084 pubmed publisher
|
| Yang Y, Lee J, Jo H, Park S, Chang I, Muallem S, et al. Homer2 protein regulates plasma membrane Ca²⁺-ATPase-mediated Ca²⁺ signaling in mouse parotid gland acinar cells. J Biol Chem. 2014;289:24971-9 pubmed publisher
|
| Cooley N, Grubb D, Luo J, Woodcock E. The phosphatidylinositol(4,5)bisphosphate-binding sequence of transient receptor potential channel canonical 4? is critical for its contribution to cardiomyocyte hypertrophy. Mol Pharmacol. 2014;86:399-405 pubmed publisher
|
| Keam S, Young P, McCorkindale A, Dang T, Clancy J, Humphreys D, et al. The human Piwi protein Hiwi2 associates with tRNA-derived piRNAs in somatic cells. Nucleic Acids Res. 2014;42:8984-95 pubmed publisher
|
| Roper S, Chrysanthou S, Senner C, Sienerth A, Gnan S, Murray A, et al. ADP-ribosyltransferases Parp1 and Parp7 safeguard pluripotency of ES cells. Nucleic Acids Res. 2014;42:8914-27 pubmed publisher
|
| Luteijn R, Hoelen H, Kruse E, van Leeuwen W, Grootens J, Horst D, et al. Cowpox virus protein CPXV012 eludes CTLs by blocking ATP binding to TAP. J Immunol. 2014;193:1578-89 pubmed publisher
|
| Markham N, Doll C, Dohn M, Miller R, Yu H, Coffey R, et al. DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia. Mol Biol Cell. 2014;25:2592-603 pubmed publisher
|
| Lodato S, Molyneaux B, Zuccaro E, Goff L, Chen H, Yuan W, et al. Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons. Nat Neurosci. 2014;17:1046-54 pubmed publisher
|
| Bernatik O, Sedova K, Schille C, Ganji R, Cervenka I, Trantirek L, et al. Functional analysis of dishevelled-3 phosphorylation identifies distinct mechanisms driven by casein kinase 1ϵ and frizzled5. J Biol Chem. 2014;289:23520-33 pubmed publisher
|
| Sidik S, Hackett C, Tran F, Westwood N, Lourido S. Efficient genome engineering of Toxoplasma gondii using CRISPR/Cas9. PLoS ONE. 2014;9:e100450 pubmed publisher
|
| Jamin A, Thunuguntla P, Wicklund A, Jones C, Wiebe M. Barrier to auto integration factor becomes dephosphorylated during HSV-1 Infection and Can Act as a host defense by impairing viral DNA replication and gene expression. PLoS ONE. 2014;9:e100511 pubmed publisher
|
| Subramanian A, Schilling T. Thrombospondin-4 controls matrix assembly during development and repair of myotendinous junctions. elife. 2014;3: pubmed publisher
|
| Macadangdang B, Oberai A, Spektor T, Campos O, Sheng F, Carey M, et al. Evolution of histone 2A for chromatin compaction in eukaryotes. elife. 2014;3: pubmed publisher
|
| Sellers K, Zyka V, Lumsden A, Delogu A. Transcriptional control of GABAergic neuronal subtype identity in the thalamus. Neural Dev. 2014;9:14 pubmed publisher
|
| Wu X, Wang Y, Wu Q, Cheng W, Liu W, Zhao Y, et al. HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression. Blood. 2014;124:1335-43 pubmed publisher
|
| Christensen L, Holm A, Rantala J, Kallioniemi O, Rasmussen M, Ostenfeld M, et al. Functional screening identifies miRNAs influencing apoptosis and proliferation in colorectal cancer. PLoS ONE. 2014;9:e96767 pubmed publisher
|
| Tu K, Yang W, Li C, Zheng X, Lu Z, Guo C, et al. Fbxw7 is an independent prognostic marker and induces apoptosis and growth arrest by regulating YAP abundance in hepatocellular carcinoma. Mol Cancer. 2014;13:110 pubmed publisher
|
| Failler M, Gee H, Krug P, Joo K, Halbritter J, Belkacem L, et al. Mutations of CEP83 cause infantile nephronophthisis and intellectual disability. Am J Hum Genet. 2014;94:905-14 pubmed publisher
|
| Wan Y, Yang Y, Leng Q, Lan B, Jia H, Liu Y, et al. Vav1 increases Bcl-2 expression by selective activation of Rac2-Akt in leukemia T cells. Cell Signal. 2014;26:2202-9 pubmed publisher
|
| Jin H, Zhao J, Wu L, Kim J, Yu J. Cooperativity and equilibrium with FOXA1 define the androgen receptor transcriptional program. Nat Commun. 2014;5:3972 pubmed publisher
|
| van Gent R, Di Sanza C, van den Broek N, Fleskens V, Veenstra A, Stout G, et al. SIRT1 mediates FOXA2 breakdown by deacetylation in a nutrient-dependent manner. PLoS ONE. 2014;9:e98438 pubmed publisher
|
| Evans J, Hines K, Forsythe J, Erdoğan B, Shi M, Hill S, et al. Phosphorylation of serine 106 in Asef2 regulates cell migration and adhesion turnover. J Proteome Res. 2014;13:3303-13 pubmed publisher
|
| Lee Y, Dominy J, Choi Y, Jurczak M, Tolliday N, Camporez J, et al. Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression. Nature. 2014;510:547-51 pubmed publisher
|
| Rajgor D, Mellad J, Soong D, Rattner J, Fritzler M, Shanahan C. Mammalian microtubule P-body dynamics are mediated by nesprin-1. J Cell Biol. 2014;205:457-75 pubmed publisher
|
| Wang X, Bledsoe K, Graham R, Asmann Y, Viswanatha D, Lewis J, et al. Recurrent PAX3-MAML3 fusion in biphenotypic sinonasal sarcoma. Nat Genet. 2014;46:666-8 pubmed publisher
|
| Hsieh F, Chen N, Yao Y, Wang S, Chen J, Lai C, et al. The transcriptional repression activity of STAF65γ is facilitated by promoter tethering and nuclear import of class IIa histone deacetylases. Biochim Biophys Acta. 2014;1839:579-91 pubmed publisher
|
| Mazur P, Reynoird N, Khatri P, Jansen P, Wilkinson A, Liu S, et al. SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer. Nature. 2014;510:283-7 pubmed publisher
|
| Zhao C, Nie H, Shen Q, Zhang S, Lukowitz W, Tang D. EDR1 physically interacts with MKK4/MKK5 and negatively regulates a MAP kinase cascade to modulate plant innate immunity. PLoS Genet. 2014;10:e1004389 pubmed publisher
|
| Calderon M, Verway M, Benslama R, Birlea M, Bouttier M, Dimitrov V, et al. Ligand-dependent corepressor contributes to transcriptional repression by C2H2 zinc-finger transcription factor ZBRK1 through association with KRAB-associated protein-1. Nucleic Acids Res. 2014;42:7012-27 pubmed publisher
|
| Kitagawa K, Shibata K, Matsumoto A, Matsumoto M, Ohhata T, Nakayama K, et al. Fbw7 targets GATA3 through cyclin-dependent kinase 2-dependent proteolysis and contributes to regulation of T-cell development. Mol Cell Biol. 2014;34:2732-44 pubmed
|
| Eldeeb M, Fahlman R. The anti-apoptotic form of tyrosine kinase Lyn that is generated by proteolysis is degraded by the N-end rule pathway. Oncotarget. 2014;5:2714-22 pubmed
|
| Wang N, Lo Presti L, Zhu Y, Kang M, Wu Z, Martin S, et al. The novel proteins Rng8 and Rng9 regulate the myosin-V Myo51 during fission yeast cytokinesis. J Cell Biol. 2014;205:357-75 pubmed publisher
|
| Liu J, Zhang C, Lin M, Zhu W, Liang Y, Hong X, et al. Glutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinoma. Oncotarget. 2014;5:2635-47 pubmed
|
| Zuccotti P, Colombrita C, Moncini S, Barbieri A, Lunghi M, Gelfi C, et al. hnRNPA2/B1 and nELAV proteins bind to a specific U-rich element in CDK5R1 3'-UTR and oppositely regulate its expression. Biochim Biophys Acta. 2014;1839:506-16 pubmed publisher
|
| Sun Y, Chung H, Woo A, Lin V. Protein arginine methyltransferase 6 enhances ligand-dependent and -independent activity of estrogen receptor ? via distinct mechanisms. Biochim Biophys Acta. 2014;1843:2067-78 pubmed publisher
|
| Skene P, Hernandez A, Groudine M, Henikoff S. The nucleosomal barrier to promoter escape by RNA polymerase II is overcome by the chromatin remodeler Chd1. elife. 2014;3:e02042 pubmed publisher
|
| Deaton M, Spear A, Faaberg K, Pegan S. The vOTU domain of highly-pathogenic porcine reproductive and respiratory syndrome virus displays a differential substrate preference. Virology. 2014;454-455:247-53 pubmed publisher
|
| Sharifi H, Furuya A, Jellinger R, Nekorchuk M, de Noronha C. Cullin4A and cullin4B are interchangeable for HIV Vpr and Vpx action through the CRL4 ubiquitin ligase complex. J Virol. 2014;88:6944-58 pubmed publisher
|
| He H, Singh I, Wek S, Dey S, Baird T, Wek R, et al. Crystal structures of GCN2 protein kinase C-terminal domains suggest regulatory differences in yeast and mammals. J Biol Chem. 2014;289:15023-34 pubmed publisher
|
| Patoine A, Gaumond M, Jaiswal P, Fassier F, Rauch F, Moffatt P. Topological mapping of BRIL reveals a type II orientation and effects of osteogenesis imperfecta mutations on its cellular destination. J Bone Miner Res. 2014;29:2004-16 pubmed publisher
|
| Duval N, Daubas P, Bourcier de Carbon C, St Cloment C, Tinevez J, Lopes M, et al. Msx1 and Msx2 act as essential activators of Atoh1 expression in the murine spinal cord. Development. 2014;141:1726-36 pubmed publisher
|
| Lussier M, Gu X, Lu W, Roche K. Casein kinase 2 phosphorylates GluA1 and regulates its surface expression. Eur J Neurosci. 2014;39:1148-58 pubmed publisher
|
| Gürtler C, Carty M, Kearney J, Schattgen S, Ding A, Fitzgerald K, et al. SARM regulates CCL5 production in macrophages by promoting the recruitment of transcription factors and RNA polymerase II to the Ccl5 promoter. J Immunol. 2014;192:4821-32 pubmed publisher
|
| Gregory D, Olinger G, Lucas T, Johnson M. Diverse viral glycoproteins as well as CD4 co-package into the same human immunodeficiency virus (HIV-1) particles. Retrovirology. 2014;11:28 pubmed publisher
|
| Chen P, Qin L, Zhuang Z, Tellides G, Lax I, Schlessinger J, et al. The docking protein FRS2? is a critical regulator of VEGF receptors signaling. Proc Natl Acad Sci U S A. 2014;111:5514-9 pubmed publisher
|
| Bejarano E, Yuste A, Patel B, Stout R, Spray D, Cuervo A. Connexins modulate autophagosome biogenesis. Nat Cell Biol. 2014;16:401-14 pubmed publisher
|
| Wu G, Diaz A, Paugh B, Rankin S, Ju B, Li Y, et al. The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma. Nat Genet. 2014;46:444-450 pubmed publisher
|
| Park R, El Guindy A, Heston L, Lin S, Yu K, Nagy M, et al. Nuclear translocation and regulation of intranuclear distribution of cytoplasmic poly(A)-binding protein are distinct processes mediated by two Epstein Barr virus proteins. PLoS ONE. 2014;9:e92593 pubmed publisher
|
| Chen L, Wang Z, Aleshin A, Chen F, Chen J, Jiang F, et al. Sulindac-derived RXR? modulators inhibit cancer cell growth by binding to a novel site. Chem Biol. 2014;21:596-607 pubmed publisher
|
| Moissoglu K, Kiessling V, Wan C, Hoffman B, Norambuena A, Tamm L, et al. Regulation of Rac1 translocation and activation by membrane domains and their boundaries. J Cell Sci. 2014;127:2565-76 pubmed publisher
|
| van der Laan S, Golfetto E, Vanacker J, Maiorano D. Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells. PLoS ONE. 2014;9:e93663 pubmed publisher
|
| Carter R, Grisanti L, Yu J, Repas A, Woodall M, Ibetti J, et al. Dynamic mass redistribution analysis of endogenous ?-adrenergic receptor signaling in neonatal rat cardiac fibroblasts. Pharmacol Res Perspect. 2014;2: pubmed publisher
|
| Kannan K, Coarfa C, Rajapakshe K, Hawkins S, Matzuk M, Milosavljevic A, et al. CDKN2D-WDFY2 is a cancer-specific fusion gene recurrent in high-grade serous ovarian carcinoma. PLoS Genet. 2014;10:e1004216 pubmed publisher
|
| Uechi H, Hamazaki J, Murata S. Characterization of the testis-specific proteasome subunit ?4s in mammals. J Biol Chem. 2014;289:12365-74 pubmed publisher
|
| Hashimoto Y, Shirane M, Matsuzaki F, Saita S, Ohnishi T, Nakayama K. Protrudin regulates endoplasmic reticulum morphology and function associated with the pathogenesis of hereditary spastic paraplegia. J Biol Chem. 2014;289:12946-61 pubmed publisher
|
| Lin X, Ruiz J, Bajraktari I, Ohman R, Banerjee S, Gribble K, et al. Z-disc-associated, alternatively spliced, PDZ motif-containing protein (ZASP) mutations in the actin-binding domain cause disruption of skeletal muscle actin filaments in myofibrillar myopathy. J Biol Chem. 2014;289:13615-26 pubmed publisher
|
| Yukawa M, Akiyama T, Franke V, Mise N, Isagawa T, Suzuki Y, et al. Genome-wide analysis of the chromatin composition of histone H2A and H3 variants in mouse embryonic stem cells. PLoS ONE. 2014;9:e92689 pubmed publisher
|
| Tang X, Mahajan S, Nguyen L, Béliveau F, Leduc R, Simon J, et al. Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis. Oncotarget. 2014;5:1352-62 pubmed
|
| van der Wijst J, Blanchard M, Woodroof H, MacArtney T, Gourlay R, Hoenderop J, et al. Kinase and channel activity of TRPM6 are co-ordinated by a dimerization motif and pocket interaction. Biochem J. 2014;460:165-75 pubmed publisher
|
| Song H, Wohltmann M, Tan M, Ladenson J, Turk J. Group VIA phospholipase A2 mitigates palmitate-induced ?-cell mitochondrial injury and apoptosis. J Biol Chem. 2014;289:14194-210 pubmed publisher
|
| Jia J, Bosley A, Thompson A, Hoskins J, Cheuk A, Collins I, et al. CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cells. Cancer Res. 2014;74:2785-95 pubmed publisher
|
| King D, Barnes M, Thomsen D, Lee C. Assessing specific oligonucleotides and small molecule antibiotics for the ability to inhibit the CRD-BP-CD44 RNA interaction. PLoS ONE. 2014;9:e91585 pubmed publisher
|
| Leung J, Agarwal P, Canny M, Gong F, Robison A, Finkelstein I, et al. Nucleosome acidic patch promotes RNF168- and RING1B/BMI1-dependent H2AX and H2A ubiquitination and DNA damage signaling. PLoS Genet. 2014;10:e1004178 pubmed publisher
|
| Maze I, Chaudhury D, Dietz D, von Schimmelmann M, Kennedy P, Lobo M, et al. G9a influences neuronal subtype specification in striatum. Nat Neurosci. 2014;17:533-9 pubmed publisher
|
| Tashima Y, Stanley P. Antibodies that detect O-linked ?-D-N-acetylglucosamine on the extracellular domain of cell surface glycoproteins. J Biol Chem. 2014;289:11132-42 pubmed publisher
|
| Azzarelli R, Pacary E, Garg R, Garcez P, van den Berg D, Riou P, et al. An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration. Nat Commun. 2014;5:3405 pubmed publisher
|
| Gammage P, Rorbach J, Vincent A, Rebar E, Minczuk M. Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations. EMBO Mol Med. 2014;6:458-66 pubmed publisher
|
| Hwang W, Jiang J, Yang S, Huang T, Lan H, Teng H, et al. MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells. Nat Cell Biol. 2014;16:268-80 pubmed publisher
|
| Kim H, Lee H, Oh Y, Choi S, Hong S, Kim H, et al. The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth. Nat Commun. 2014;5:3351 pubmed publisher
|
| Nassa G, Tarallo R, Giurato G, De Filippo M, Ravo M, Rizzo F, et al. Post-transcriptional regulation of human breast cancer cell proteome by unliganded estrogen receptor ? via microRNAs. Mol Cell Proteomics. 2014;13:1076-90 pubmed publisher
|
| Joensuu M, Belevich I, Rämö O, Nevzorov I, Vihinen H, Puhka M, et al. ER sheet persistence is coupled to myosin 1c-regulated dynamic actin filament arrays. Mol Biol Cell. 2014;25:1111-26 pubmed publisher
|
| Yang Y, Flynn R, Chen Y, Qu K, Wan B, Wang K, et al. Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency. elife. 2014;3:e02046 pubmed publisher
|
| Kilander M, Petersen J, Andressen K, Ganji R, Levy F, Schuster J, et al. Disheveled regulates precoupling of heterotrimeric G proteins to Frizzled 6. FASEB J. 2014;28:2293-305 pubmed publisher
|
| Fan X, Jin W, Lu J, Wang J, Wang Y. Rapid and reversible knockdown of endogenous proteins by peptide-directed lysosomal degradation. Nat Neurosci. 2014;17:471-80 pubmed publisher
|
| Li A, Morton J, Ma Y, Karim S, Zhou Y, Faller W, et al. Fascin is regulated by slug, promotes progression of pancreatic cancer in mice, and is associated with patient outcomes. Gastroenterology. 2014;146:1386-96.e1-17 pubmed publisher
|
| Hagen S, Baumann T, Wagner H, Morath V, Kaufmann B, Fischer A, et al. Modular adeno-associated virus (rAAV) vectors used for cellular virus-directed enzyme prodrug therapy. Sci Rep. 2014;4:3759 pubmed publisher
|
| Lin L, Chen K, Abdel Khalek W, Ward J, Yang H, Chabi B, et al. Regulation of skeletal muscle oxidative capacity and muscle mass by SIRT3. PLoS ONE. 2014;9:e85636 pubmed publisher
|
| Thirunavukarasou A, Singh P, Govindarajalu G, Bandi V, Baluchamy S. E3 ubiquitin ligase Cullin4B mediated polyubiquitination of p53 for its degradation. Mol Cell Biochem. 2014;390:93-100 pubmed publisher
|
| Choudhury R, Roy S, Tsai Y, Tripathy A, Graves L, Wang Z. The splicing activator DAZAP1 integrates splicing control into MEK/Erk-regulated cell proliferation and migration. Nat Commun. 2014;5:3078 pubmed publisher
|
| Bund T, Spoden G, Koynov K, Hellmann N, Boukhallouk F, Arnold P, et al. An L2 SUMO interacting motif is important for PML localization and infection of human papillomavirus type 16. Cell Microbiol. 2014;16:1179-200 pubmed publisher
|
| Nagy P, Kárpáti M, Varga A, Pircs K, Venkei Z, Takáts S, et al. Atg17/FIP200 localizes to perilysosomal Ref(2)P aggregates and promotes autophagy by activation of Atg1 in Drosophila. Autophagy. 2014;10:453-67 pubmed publisher
|
| Feng Y, Zhang S, Huang X. A robust TALENs system for highly efficient mammalian genome editing. Sci Rep. 2014;4:3632 pubmed publisher
|
| Huot G, Vernier M, Bourdeau V, Doucet L, Saint Germain E, Gaumont Leclerc M, et al. CHES1/FOXN3 regulates cell proliferation by repressing PIM2 and protein biosynthesis. Mol Biol Cell. 2014;25:554-65 pubmed publisher
|
| de los Heros P, Alessi D, Gourlay R, Campbell D, Deak M, MacArtney T, et al. The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters. Biochem J. 2014;458:559-73 pubmed publisher
|
| Hashimoto H, Pais J, Zhang X, Saleh L, Fu Z, Dai N, et al. Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA. Nature. 2014;506:391-5 pubmed publisher
|
| Caffarelli N, Fehr A, Yu D. Cyclin A degradation by primate cytomegalovirus protein pUL21a counters its innate restriction of virus replication. PLoS Pathog. 2013;9:e1003825 pubmed publisher
|
| Edge C, Gooding C, Smith C. Dissecting domains necessary for activation and repression of splicing by Muscleblind-like protein 1. BMC Mol Biol. 2013;14:29 pubmed publisher
|
| Lee J, Kim W, Gygi S, Ye Y. Characterization of the deubiquitinating activity of USP19 and its role in endoplasmic reticulum-associated degradation. J Biol Chem. 2014;289:3510-7 pubmed publisher
|
| Ho L, Hung L, Liu F, Hou T, Lin L, Huang C, et al. Ginkgo biloba extract individually inhibits JNK activation and induces c-Jun degradation in human chondrocytes: potential therapeutics for osteoarthritis. PLoS ONE. 2013;8:e82033 pubmed publisher
|
| Wang W, Chen Y, Wang S, Hu N, Cao Z, Wang W, et al. PIASx? ligase enhances SUMO1 modification of PTEN protein as a SUMO E3 ligase. J Biol Chem. 2014;289:3217-30 pubmed publisher
|
| Andresen C, Smedegaard S, Sylvestersen K, Svensson C, Iglesias Gato D, Cazzamali G, et al. Protein interaction screening for the ankyrin repeats and suppressor of cytokine signaling (SOCS) box (ASB) family identify Asb11 as a novel endoplasmic reticulum resident ubiquitin ligase. J Biol Chem. 2014;289:2043-54 pubmed publisher
|
| Korde A, Rosselot J, Donze D. Intergenic transcriptional interference is blocked by RNA polymerase III transcription factor TFIIIB in Saccharomyces cerevisiae. Genetics. 2014;196:427-38 pubmed publisher
|
| Morris S, Baek S, Sung M, John S, Wiench M, Johnson T, et al. Overlapping chromatin-remodeling systems collaborate genome wide at dynamic chromatin transitions. Nat Struct Mol Biol. 2014;21:73-81 pubmed publisher
|
| Wilson K, Mole D, Binnie M, Homer N, Zheng X, Yard B, et al. Bacterial expression of human kynurenine 3-monooxygenase: solubility, activity, purification. Protein Expr Purif. 2014;95:96-103 pubmed publisher
|
| Richard M, Jamet S, Fouquet C, Dubacq C, Boggetto N, Pincet F, et al. Homotypic and heterotypic adhesion induced by odorant receptors and the ?2-adrenergic receptor. PLoS ONE. 2013;8:e80100 pubmed publisher
|
| Kitayama Y, Nishiwaki Ohkawa T, Sugisawa Y, Kondo T. KaiC intersubunit communication facilitates robustness of circadian rhythms in cyanobacteria. Nat Commun. 2013;4:2897 pubmed publisher
|
| Chen P, Hung J, Hickman T, Coles A, Carey J, Weng Z, et al. Hdac6 regulates Tip60-p400 function in stem cells. elife. 2013;2:e01557 pubmed publisher
|
| Gerald D, Adini I, Shechter S, Perruzzi C, Varnau J, Hopkins B, et al. RhoB controls coordination of adult angiogenesis and lymphangiogenesis following injury by regulating VEZF1-mediated transcription. Nat Commun. 2013;4:2824 pubmed publisher
|
| Han S, Komatsu Y, Murayama A, Steffensen K, Nakagawa Y, Nakajima Y, et al. Estrogen receptor ligands ameliorate fatty liver through a nonclassical estrogen receptor/Liver X receptor pathway in mice. Hepatology. 2014;59:1791-802 pubmed publisher
|
| Chiang H, Zhao Y, Song J, Liu S, Wang N, Terhorst C, et al. GEF-H1 controls microtubule-dependent sensing of nucleic acids for antiviral host defenses. Nat Immunol. 2014;15:63-71 pubmed publisher
|
| Zhang C, Hong Z, Ma W, Ma D, Qian Y, Xie W, et al. Drosophila UTX coordinates with p53 to regulate ku80 expression in response to DNA damage. PLoS ONE. 2013;8:e78652 pubmed publisher
|
| Zaborske J, Zeitler B, Culbertson M. Multiple transcripts from a 3'-UTR reporter vary in sensitivity to nonsense-mediated mRNA decay in Saccharomyces cerevisiae. PLoS ONE. 2013;8:e80981 pubmed publisher
|
| Inturi R, Thaduri S, Punga T. Adenovirus precursor pVII protein stability is regulated by its propeptide sequence. PLoS ONE. 2013;8:e80617 pubmed publisher
|
| Simard E, Kovacs J, Miller W, Kim J, Grandbois M, Lefkowitz R. ?-Arrestin regulation of myosin light chain phosphorylation promotes AT1aR-mediated cell contraction and migration. PLoS ONE. 2013;8:e80532 pubmed publisher
|
| Lee J, Sugiyama T, Liu Y, Wang J, Gu X, Lei J, et al. Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells. elife. 2013;2:e00940 pubmed publisher
|
| Nekorchuk M, Sharifi H, Furuya A, Jellinger R, de Noronha C. HIV relies on neddylation for ubiquitin ligase-mediated functions. Retrovirology. 2013;10:138 pubmed publisher
|
| Bergiers I, Bridoux L, Nguyen N, Twizere J, Rezsohazy R. The homeodomain transcription factor Hoxa2 interacts with and promotes the proteasomal degradation of the E3 ubiquitin protein ligase RCHY1. PLoS ONE. 2013;8:e80387 pubmed publisher
|
| Bennett C, Chen Y, Vignali M, Lo R, Mason A, Unal A, et al. Protein interaction analysis of senataxin and the ALS4 L389S mutant yields insights into senataxin post-translational modification and uncovers mutant-specific binding with a brain cytoplasmic RNA-encoded peptide. PLoS ONE. 2013;8:e78837 pubmed publisher
|
| Chang Y, Moser B, Nakamura T. Fission yeast shelterin regulates DNA polymerases and Rad3(ATR) kinase to limit telomere extension. PLoS Genet. 2013;9:e1003936 pubmed publisher
|
| Zhang H, Lin W, Kannan K, Luo L, Li J, Chao P, et al. Aberrant chimeric RNA GOLM1-MAK10 encoding a secreted fusion protein as a molecular signature for human esophageal squamous cell carcinoma. Oncotarget. 2013;4:2135-43 pubmed
|
| Tanigawa S, Lee C, Lin C, Ku C, Hasegawa H, Qin S, et al. Jun dimerization protein 2 is a critical component of the Nrf2/MafK complex regulating the response to ROS homeostasis. Cell Death Dis. 2013;4:e921 pubmed publisher
|
| Wei Q, Xu Q, Zhang Y, Li Y, Zhang Q, Hu Z, et al. Transition fibre protein FBF1 is required for the ciliary entry of assembled intraflagellar transport complexes. Nat Commun. 2013;4:2750 pubmed publisher
|
| Kato H, Kira S, Kawamukai M. The transcription factors Atf1 and Pcr1 are essential for transcriptional induction of the extracellular maltase Agl1 in fission yeast. PLoS ONE. 2013;8:e80572 pubmed publisher
|
| Kuo P, Chiang H, Wang Y, Kuo Y, Chen M, Yu I, et al. SEPT12-microtubule complexes are required for sperm head and tail formation. Int J Mol Sci. 2013;14:22102-16 pubmed publisher
|
| Pearce L, Atanassova N, Banton M, Bottomley B, van der Klaauw A, Revelli J, et al. KSR2 mutations are associated with obesity, insulin resistance, and impaired cellular fuel oxidation. Cell. 2013;155:765-77 pubmed
|
| Castelli M, Boca M, Chiaravalli M, Ramalingam H, Rowe I, Distefano G, et al. Polycystin-1 binds Par3/aPKC and controls convergent extension during renal tubular morphogenesis. Nat Commun. 2013;4:2658 pubmed publisher
|
| Correia B, Cerqueira S, Beauchemin C, Pires de Miranda M, Li S, Ponnusamy R, et al. Crystal structure of the gamma-2 herpesvirus LANA DNA binding domain identifies charged surface residues which impact viral latency. PLoS Pathog. 2013;9:e1003673 pubmed publisher
|
| Ji X, Wu Y, Yan J, Mehrens J, Yang H, Delucia M, et al. Mechanism of allosteric activation of SAMHD1 by dGTP. Nat Struct Mol Biol. 2013;20:1304-9 pubmed publisher
|
| Börner K, Niopek D, Cotugno G, Kaldenbach M, Pankert T, Willemsen J, et al. Robust RNAi enhancement via human Argonaute-2 overexpression from plasmids, viral vectors and cell lines. Nucleic Acids Res. 2013;41:e199 pubmed publisher
|
| Sollome J, Thavathiru E, Camenisch T, Vaillancourt R. HER2/HER3 regulates extracellular acidification and cell migration through MTK1 (MEKK4). Cell Signal. 2014;26:70-82 pubmed publisher
|
| Prystowsky M, Feeney K, Kawachi N, Montagna C, Willmott M, Wasson C, et al. Inhibition of Plk1 and Cyclin B1 expression results in panobinostat-induced G₂ delay and mitotic defects. Sci Rep. 2013;3:2640 pubmed publisher
|
| Jeyasekharan A, Liu Y, Hattori H, Pisupati V, Jonsdottir A, Rajendra E, et al. A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization. Nat Struct Mol Biol. 2013;20:1191-8 pubmed publisher
|
| Guan Q, Wu J, Yue X, Zhang Y, Zhu J. A nuclear calcium-sensing pathway is critical for gene regulation and salt stress tolerance in Arabidopsis. PLoS Genet. 2013;9:e1003755 pubmed publisher
|
| Dhani D, Goult B, George G, Rogerson D, Bitton D, Miller C, et al. Mzt1/Tam4, a fission yeast MOZART1 homologue, is an essential component of the γ-tubulin complex and directly interacts with GCP3(Alp6). Mol Biol Cell. 2013;24:3337-49 pubmed publisher
|
| Adelman C, Lolo R, Birkbak N, Murina O, Matsuzaki K, Horejsi Z, et al. HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis. Nature. 2013;502:381-4 pubmed publisher
|
| Wang Y, Gogol Döring A, Hu H, Fröhler S, Ma Y, Jens M, et al. Integrative analysis revealed the molecular mechanism underlying RBM10-mediated splicing regulation. EMBO Mol Med. 2013;5:1431-42 pubmed publisher
|
| Fujii W, Kawasaki K, Sugiura K, Naito K. Efficient generation of large-scale genome-modified mice using gRNA and CAS9 endonuclease. Nucleic Acids Res. 2013;41:e187 pubmed publisher
|
| Yang S, Counter C. Cell cycle regulated phosphorylation of the telomere-associated protein TIN2. PLoS ONE. 2013;8:e71697 pubmed publisher
|
| Colley S, Wintle L, Searles R, Russell V, Firman R, Smith S, et al. Loss of the nuclear receptor corepressor SLIRP compromises male fertility. PLoS ONE. 2013;8:e70700 pubmed publisher
|
| Chen Z, Jaafar L, Agyekum D, Xiao H, Wade M, Kumaran R, et al. Receptor-mediated delivery of engineered nucleases for genome modification. Nucleic Acids Res. 2013;41:e182 pubmed publisher
|
| Okuda J, Niizuma S, Shioi T, Kato T, Inuzuka Y, Kawashima T, et al. Persistent overexpression of phosphoglycerate mutase, a glycolytic enzyme, modifies energy metabolism and reduces stress resistance of heart in mice. PLoS ONE. 2013;8:e72173 pubmed publisher
|
| Zhang Y, Seo S, Bhattarai S, Bugge K, Searby C, Zhang Q, et al. BBS mutations modify phenotypic expression of CEP290-related ciliopathies. Hum Mol Genet. 2014;23:40-51 pubmed publisher
|
| Chen X, Paudyal S, Chin R, You Z. PCNA promotes processive DNA end resection by Exo1. Nucleic Acids Res. 2013;41:9325-38 pubmed publisher
|
| Wang J, Chen J, Enns C, Mayinger P. The first transmembrane domain of lipid phosphatase SAC1 promotes Golgi localization. PLoS ONE. 2013;8:e71112 pubmed publisher
|
| Singh K, Wachsmuth L, Kulozik A, Gehring N. Two mammalian MAGOH genes contribute to exon junction complex composition and nonsense-mediated decay. RNA Biol. 2013;10:1291-8 pubmed publisher
|
| Lai Z, Moravcová S, Canitrot Y, Andrzejewski L, Walshe D, Rea S. Msl2 is a novel component of the vertebrate DNA damage response. PLoS ONE. 2013;8:e68549 pubmed publisher
|
| Zhang Y, Wang L. Characterization of the mitochondrial localization of the nuclear receptor SHP and regulation of its subcellular distribution by interaction with Bcl2 and HNF4?. PLoS ONE. 2013;8:e68491 pubmed publisher
|
| Feng Y, Singleton D, Guo C, Gardner A, Pakala S, Kumar R, et al. DNA homologous recombination factor SFR1 physically and functionally interacts with estrogen receptor alpha. PLoS ONE. 2013;8:e68075 pubmed publisher
|
| Guo H, Wei W, Wei Z, Liu X, Evans S, Yang W, et al. Identification of critical regions in human SAMHD1 required for nuclear localization and Vpx-mediated degradation. PLoS ONE. 2013;8:e66201 pubmed publisher
|
| Baumgartner R, Stocker H, Hafen E. The RNA-binding proteins FMR1, rasputin and caprin act together with the UBA protein lingerer to restrict tissue growth in Drosophila melanogaster. PLoS Genet. 2013;9:e1003598 pubmed publisher
|
| Laurenceau R, Pehau Arnaudet G, Baconnais S, Gault J, Malosse C, Dujeancourt A, et al. A type IV pilus mediates DNA binding during natural transformation in Streptococcus pneumoniae. PLoS Pathog. 2013;9:e1003473 pubmed publisher
|
| Taipale M, Krykbaeva I, Whitesell L, Santagata S, Zhang J, Liu Q, et al. Chaperones as thermodynamic sensors of drug-target interactions reveal kinase inhibitor specificities in living cells. Nat Biotechnol. 2013;31:630-7 pubmed publisher
|
| Haldar A, Saka H, Piro A, Dunn J, Henry S, Taylor G, et al. IRG and GBP host resistance factors target aberrant, "non-self" vacuoles characterized by the missing of "self" IRGM proteins. PLoS Pathog. 2013;9:e1003414 pubmed publisher
|
| Saito Y, Takeda J, Okada M, Kobayashi J, Kato A, Hirota K, et al. The proteasome factor Bag101 binds to Rad22 and suppresses homologous recombination. Sci Rep. 2013;3:2022 pubmed publisher
|
| Graf R, Munschauer M, Mastrobuoni G, Mayr F, Heinemann U, Kempa S, et al. Identification of LIN28B-bound mRNAs reveals features of target recognition and regulation. RNA Biol. 2013;10:1146-59 pubmed publisher
|
| Poulsen S, Hansen R, Wagner S, van Cuijk L, van Belle G, Streicher W, et al. RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response. J Cell Biol. 2013;201:797-807 pubmed publisher
|
| Sridharan R, Gonzales Cope M, Chronis C, Bonora G, McKee R, Huang C, et al. Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1? in reprogramming to pluripotency. Nat Cell Biol. 2013;15:872-82 pubmed publisher
|
| Mahendram S, Kelly K, Paez Parent S, Mahmood S, Polena E, Cooney A, et al. Ectopic ?-catenin expression partially mimics the effects of stabilized ?-catenin on embryonic stem cell differentiation. PLoS ONE. 2013;8:e65320 pubmed publisher
|
| Gransee H, Zhan W, Sieck G, Mantilla C. Targeted delivery of TrkB receptor to phrenic motoneurons enhances functional recovery of rhythmic phrenic activity after cervical spinal hemisection. PLoS ONE. 2013;8:e64755 pubmed publisher
|
| Johansson M, Oudin A, Tiemann K, Bernard A, Golebiewska A, Keunen O, et al. The soluble form of the tumor suppressor Lrig1 potently inhibits in vivo glioma growth irrespective of EGF receptor status. Neuro Oncol. 2013;15:1200-11 pubmed publisher
|
| Rivkin E, Almeida S, Ceccarelli D, Juang Y, MacLean T, Srikumar T, et al. The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis. Nature. 2013;498:318-24 pubmed publisher
|
| Soldano A, Okray Z, Janovská P, Tmejová K, Reynaud E, Claeys A, et al. The Drosophila homologue of the amyloid precursor protein is a conserved modulator of Wnt PCP signaling. PLoS Biol. 2013;11:e1001562 pubmed publisher
|
| Gong L, Suchard M, Bloom J. Stability-mediated epistasis constrains the evolution of an influenza protein. elife. 2013;2:e00631 pubmed publisher
|
| Davis H, Lewis A, Behrens A, Tomlinson I. Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines. Gut. 2014;63:792-9 pubmed publisher
|
| Martin E, Caubit X, Airik R, Vola C, Fatmi A, Kispert A, et al. TSHZ3 and SOX9 regulate the timing of smooth muscle cell differentiation in the ureter by reducing myocardin activity. PLoS ONE. 2013;8:e63721 pubmed publisher
|
| Merz K, Lie D. Evidence that Doublecortin is dispensable for the development of adult born neurons in mice. PLoS ONE. 2013;8:e62693 pubmed publisher
|
| Paeschke K, Bochman M, Garcia P, Cejka P, Friedman K, Kowalczykowski S, et al. Pif1 family helicases suppress genome instability at G-quadruplex motifs. Nature. 2013;497:458-62 pubmed publisher
|
| Hung S, Wong R, Sharov A, Nakatake Y, Yu H, Ko M. Repression of global protein synthesis by Eif1a-like genes that are expressed specifically in the two-cell embryos and the transient Zscan4-positive state of embryonic stem cells. DNA Res. 2013;20:391-402 pubmed publisher
|
| Stockert J, Wolf A, Kaddatz K, Schnitzer E, Finkernagel F, Meissner W, et al. Regulation of TAK1/TAB1-mediated IL-1? signaling by cytoplasmic PPAR?/?. PLoS ONE. 2013;8:e63011 pubmed publisher
|
| Nicholson T, Singh A, Su H, Hevi S, Wang J, Bajko J, et al. A hypomorphic lsd1 allele results in heart development defects in mice. PLoS ONE. 2013;8:e60913 pubmed publisher
|
| Kelly C, Thymiakou E, Dixon J, Tanaka S, Godwin J, Episkopou V. Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension. PLoS Biol. 2013;11:e1001538 pubmed publisher
|
| Betschinger J, Nichols J, Dietmann S, Corrin P, Paddison P, Smith A. Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3. Cell. 2013;153:335-47 pubmed publisher
|
| Maruyama A, Mimura J, Harada N, Itoh K. Nrf2 activation is associated with Z-DNA formation in the human HO-1 promoter. Nucleic Acids Res. 2013;41:5223-34 pubmed publisher
|
| Li W, Chiang Y, Coaker G. The HopQ1 effector's nucleoside hydrolase-like domain is required for bacterial virulence in arabidopsis and tomato, but not host recognition in tobacco. PLoS ONE. 2013;8:e59684 pubmed publisher
|
| Fujii W, Kano K, Sugiura K, Naito K. Repeatable construction method for engineered zinc finger nuclease based on overlap extension PCR and TA-cloning. PLoS ONE. 2013;8:e59801 pubmed publisher
|
| Gooding C, Edge C, Lorenz M, Coelho M, Winters M, Kaminski C, et al. MBNL1 and PTB cooperate to repress splicing of Tpm1 exon 3. Nucleic Acids Res. 2013;41:4765-82 pubmed publisher
|
| Huang L, Jin J, Deighan P, Kiner E, McReynolds L, Lieberman J. Efficient and specific gene knockdown by small interfering RNAs produced in bacteria. Nat Biotechnol. 2013;31:350-6 pubmed publisher
|
| Feldman D, Chen C, Punj V, Machida K. The TBC1D15 oncoprotein controls stem cell self-renewal through destabilization of the Numb-p53 complex. PLoS ONE. 2013;8:e57312 pubmed publisher
|
| Rodriguez Gil D, Hu W, Greer C. Dishevelled proteins are associated with olfactory sensory neuron presynaptic terminals. PLoS ONE. 2013;8:e56561 pubmed publisher
|
| Dunnick W, Shi J, Fontaine C, Collins J. Transgenes of the mouse immunoglobulin heavy chain locus, lacking distal elements in the 3' regulatory region, are impaired for class switch recombination. PLoS ONE. 2013;8:e55842 pubmed publisher
|
| McCoy F, Darbandi R, Chen S, Eckard L, Dodd K, Jones K, et al. Metabolic regulation of CaMKII protein and caspases in Xenopus laevis egg extracts. J Biol Chem. 2013;288:8838-48 pubmed publisher
|
| Ohta A, Schumacher F, Mehellou Y, Johnson C, Knebel A, MacArtney T, et al. The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction. Biochem J. 2013;451:111-22 pubmed publisher
|
| Porter K, Nallathambi J, Lin Y, Liton P. Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: implications for glaucoma pathogenesis. Autophagy. 2013;9:581-94 pubmed publisher
|
| Bradley J, Chan J, Hagood J. Effect of the GPI anchor of human Thy-1 on antibody recognition and function. Lab Invest. 2013;93:365-74 pubmed publisher
|
| Koreishi M, Yu S, Oda M, Honjo Y, Satoh A. CK2 phosphorylates Sec31 and regulates ER-To-Golgi trafficking. PLoS ONE. 2013;8:e54382 pubmed publisher
|
| Watanabe S, Sanuki R, Ueno S, Koyasu T, Hasegawa T, Furukawa T. Tropisms of AAV for subretinal delivery to the neonatal mouse retina and its application for in vivo rescue of developmental photoreceptor disorders. PLoS ONE. 2013;8:e54146 pubmed publisher
|
| Buss H, Handschick K, Jurrmann N, Pekkonen P, Beuerlein K, Müller H, et al. Cyclin-dependent kinase 6 phosphorylates NF-?B P65 at serine 536 and contributes to the regulation of inflammatory gene expression. PLoS ONE. 2012;7:e51847 pubmed publisher
|
| Liew C, Boucher J, Cheong J, Vernochet C, Koh H, Mallol C, et al. Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance. Nat Med. 2013;19:217-26 pubmed publisher
|
| Xie L, Gazin C, Park S, Zhu L, Debily M, Kittler E, et al. A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells. PLoS Genet. 2012;8:e1003151 pubmed publisher
|
| Luo M, Yu C, Chen F, Zhao L, Tian G, Liu X, et al. Histone deacetylase HDA6 is functionally associated with AS1 in repression of KNOX genes in arabidopsis. PLoS Genet. 2012;8:e1003114 pubmed publisher
|
| Lau P, Cheung P. Elucidating combinatorial histone modifications and crosstalks by coupling histone-modifying enzyme with biotin ligase activity. Nucleic Acids Res. 2013;41:e49 pubmed publisher
|
| Santoro S, Dulac C. The activity-dependent histone variant H2BE modulates the life span of olfactory neurons. elife. 2012;1:e00070 pubmed publisher
|
| Otomo C, Metlagel Z, Takaesu G, Otomo T. Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy. Nat Struct Mol Biol. 2013;20:59-66 pubmed publisher
|
| Li M, Cao W, Liu H, Zhang W, Liu X, Cai Z, et al. MCPIP1 down-regulates IL-2 expression through an ARE-independent pathway. PLoS ONE. 2012;7:e49841 pubmed publisher
|
| Cherukuri P, DeCastro A, Balboni A, Downey S, Liu J, Hutchinson J, et al. Phosphorylation of ?Np63? via a novel TGF?/ALK5 signaling mechanism mediates the anti-clonogenic effects of TGF?. PLoS ONE. 2012;7:e50066 pubmed publisher
|
| Alzu A, Bermejo R, Begnis M, Lucca C, Piccini D, Carotenuto W, et al. Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes. Cell. 2012;151:835-846 pubmed publisher
|
| Metzner M, Jack H, Wabl M. LINE-1 retroelements complexed and inhibited by activation induced cytidine deaminase. PLoS ONE. 2012;7:e49358 pubmed publisher
|
| Na J, Lee K, Kim H, Shin J, Na W, Jeong H, et al. Role of type II protein arginine methyltransferase 5 in the regulation of Circadian Per1 gene. PLoS ONE. 2012;7:e48152 pubmed publisher
|
| Nandakumar J, Bell C, Weidenfeld I, Zaug A, Leinwand L, Cech T. The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity. Nature. 2012;492:285-9 pubmed publisher
|
| Moriarty T, Shi M, Lin Y, Ebady R, Zhou H, Odisho T, et al. Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules. Mol Microbiol. 2012;86:1116-31 pubmed publisher
|
| Lambert B, Vandeputte J, Remacle S, Bergiers I, Simonis N, Twizere J, et al. Protein interactions of the transcription factor Hoxa1. BMC Dev Biol. 2012;12:29 pubmed publisher
|
| Ziesché E, Kettner Buhrow D, Weber A, Wittwer T, Jurida L, Soelch J, et al. The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-?B. Nucleic Acids Res. 2013;41:90-109 pubmed publisher
|
| Chen H, Ouseph M, Li J, Pécot T, Chokshi V, Kent L, et al. Canonical and atypical E2Fs regulate the mammalian endocycle. Nat Cell Biol. 2012;14:1192-202 pubmed publisher
|
| Deuschle U, Schuler J, Schulz A, Schlüter T, Kinzel O, Abel U, et al. FXR controls the tumor suppressor NDRG2 and FXR agonists reduce liver tumor growth and metastasis in an orthotopic mouse xenograft model. PLoS ONE. 2012;7:e43044 pubmed publisher
|
| Zhong B, Liu X, Wang X, Chang S, Liu X, Wang A, et al. Negative regulation of IL-17-mediated signaling and inflammation by the ubiquitin-specific protease USP25. Nat Immunol. 2012;13:1110-7 pubmed publisher
|
| Mund A, Schubert T, Staege H, Kinkley S, Reumann K, Kriegs M, et al. SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response. Nucleic Acids Res. 2012;40:11363-79 pubmed publisher
|
| Durand C, Decker E, Roeth R, Schneider K, Rappold G. The homeobox transcription factor HOXA9 is a regulator of SHOX in U2OS cells and chicken micromass cultures. PLoS ONE. 2012;7:e45369 pubmed publisher
|
| Rothbart S, Krajewski K, Nady N, Tempel W, Xue S, Badeaux A, et al. Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation. Nat Struct Mol Biol. 2012;19:1155-60 pubmed publisher
|
| Valente R, Ehlers E, Xu D, Ahmad H, Steadman A, Blasnitz L, et al. Toll-like receptor 7 stimulates the expression of Epstein-Barr virus latent membrane protein 1. PLoS ONE. 2012;7:e43317 pubmed publisher
|
| Cox J, Wilder P, Desler M, Rizzino A. Elevating SOX2 levels deleteriously affects the growth of medulloblastoma and glioblastoma cells. PLoS ONE. 2012;7:e44087 pubmed publisher
|
| Sabag A, Bode J, Fink D, Kigel B, Kugler W, Neufeld G. Semaphorin-3D and semaphorin-3E inhibit the development of tumors from glioblastoma cells implanted in the cortex of the brain. PLoS ONE. 2012;7:e42912 pubmed publisher
|
| Ito M, Yanagi Y, Ichinohe T. Encephalomyocarditis virus viroporin 2B activates NLRP3 inflammasome. PLoS Pathog. 2012;8:e1002857 pubmed publisher
|
| Ward T, Dudasova Z, Sarkar S, Bhide M, Vlasáková D, Chovanec M, et al. Components of a Fanconi-like pathway control Pso2-independent DNA interstrand crosslink repair in yeast. PLoS Genet. 2012;8:e1002884 pubmed publisher
|
| Cherrington B, Zhang X, McElwee J, Morency E, Anguish L, Coonrod S. Potential role for PAD2 in gene regulation in breast cancer cells. PLoS ONE. 2012;7:e41242 pubmed publisher
|
| Furler R, Uittenbogaart C. GLI2 regulates TGF-?1 in human CD4+ T cells: implications in cancer and HIV pathogenesis. PLoS ONE. 2012;7:e40874 pubmed publisher
|
| Endoh M, Endo T, Endoh T, Isono K, Sharif J, Ohara O, et al. Histone H2A mono-ubiquitination is a crucial step to mediate PRC1-dependent repression of developmental genes to maintain ES cell identity. PLoS Genet. 2012;8:e1002774 pubmed publisher
|
| Dimberg L, Dimberg A, Ivarsson K, Fryknäs M, Rickardson L, Tobin G, et al. Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma. BMC Cancer. 2012;12:318 pubmed publisher
|
| Lee Y, Yu Y, Gunawardena H, Xie L, Chen X. BCLAF1 is a radiation-induced H2AX-interacting partner involved in ?H2AX-mediated regulation of apoptosis and DNA repair. Cell Death Dis. 2012;3:e359 pubmed publisher
|
| Park Y, Zhao X, Norton M, Taylor J, Eisenberg E, Greene L. Huntingtin fragments and SOD1 mutants form soluble oligomers in the cell. PLoS ONE. 2012;7:e40329 pubmed publisher
|
| Chao H, Lai Y, Lu Y, Lin C, Mai W, Huang Y. NMDAR signaling facilitates the IPO5-mediated nuclear import of CPEB3. Nucleic Acids Res. 2012;40:8484-98 pubmed
|
| Chen S, Novick P, Ferro Novick S. ER network formation requires a balance of the dynamin-like GTPase Sey1p and the Lunapark family member Lnp1p. Nat Cell Biol. 2012;14:707-16 pubmed publisher
|
| Chow K, Elgort S, Dasso M, Ullman K. Two distinct sites in Nup153 mediate interaction with the SUMO proteases SENP1 and SENP2. Nucleus. 2012;3:349-58 pubmed
|
| Bordeleau F, Myrand Lapierre M, Sheng Y, Marceau N. Keratin 8/18 regulation of cell stiffness-extracellular matrix interplay through modulation of Rho-mediated actin cytoskeleton dynamics. PLoS ONE. 2012;7:e38780 pubmed publisher
|
| Zhang Q, Tan D, Luo W, Lu J, Tan Y. Expression of CD82 in human trophoblast and its role in trophoblast invasion. PLoS ONE. 2012;7:e38487 pubmed publisher
|
| Estruch S, Buzon V, Carbó L, Schorova L, Lüders J, Estebanez Perpina E. The oncoprotein BCL11A binds to orphan nuclear receptor TLX and potentiates its transrepressive function. PLoS ONE. 2012;7:e37963 pubmed publisher
|
| Wang Q, Zhao N, Kennard S, Lilly B. Notch2 and Notch3 function together to regulate vascular smooth muscle development. PLoS ONE. 2012;7:e37365 pubmed publisher
|
| Youseff B, Holbrook E, Smolnycki K, Rappleye C. Extracellular superoxide dismutase protects Histoplasma yeast cells from host-derived oxidative stress. PLoS Pathog. 2012;8:e1002713 pubmed publisher
|
| Uringa E, Lisaingo K, Pickett H, Brind Amour J, Rohde J, Zelensky A, et al. RTEL1 contributes to DNA replication and repair and telomere maintenance. Mol Biol Cell. 2012;23:2782-92 pubmed publisher
|
| Sheng L, Zhou Y, Chen Z, Ren D, Cho K, Jiang L, et al. NF-?B–inducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon action. Nat Med. 2012;18:943-9 pubmed publisher
|
| Hu Y, Morichaud Z, Chen S, Leonetti J, Brodolin K. Mycobacterium tuberculosis RbpA protein is a new type of transcriptional activator that stabilizes the ? A-containing RNA polymerase holoenzyme. Nucleic Acids Res. 2012;40:6547-57 pubmed publisher
|
| O Sullivan N, Jahn T, Reid E, O Kane C. Reticulon-like-1, the Drosophila orthologue of the hereditary spastic paraplegia gene reticulon 2, is required for organization of endoplasmic reticulum and of distal motor axons. Hum Mol Genet. 2012;21:3356-65 pubmed publisher
|
| Ye S, Tan L, Yang R, Fang B, Qu S, Schulze E, et al. Pleiotropy of glycogen synthase kinase-3 inhibition by CHIR99021 promotes self-renewal of embryonic stem cells from refractory mouse strains. PLoS ONE. 2012;7:e35892 pubmed publisher
|
| Pranski E, Dalal N, Herskowitz J, Orr A, Roesch L, Fritz J, et al. Neuronal RING finger protein 11 (RNF11) regulates canonical NF-?B signaling. J Neuroinflammation. 2012;9:67 pubmed publisher
|
| Lin Y, Wang Y, Chen H, Kuo Y, Chiou Y, Lin H, et al. SEPTIN12 genetic variants confer susceptibility to teratozoospermia. PLoS ONE. 2012;7:e34011 pubmed publisher
|
| Tu X, Chen J, Lim J, Karner C, Lee S, Heisig J, et al. Physiological notch signaling maintains bone homeostasis via RBPjk and Hey upstream of NFATc1. PLoS Genet. 2012;8:e1002577 pubmed publisher
|
| Kim S, Lee J, Eshed Williams L, Zilberman D, Sung Z. EMF1 and PRC2 cooperate to repress key regulators of Arabidopsis development. PLoS Genet. 2012;8:e1002512 pubmed publisher
|
| Wurm T, Wright D, Polakowski N, Mesnard J, Lemasson I. The HTLV-1-encoded protein HBZ directly inhibits the acetyl transferase activity of p300/CBP. Nucleic Acids Res. 2012;40:5910-25 pubmed publisher
|
| Sarkar A, Zohn I. Hectd1 regulates intracellular localization and secretion of Hsp90 to control cellular behavior of the cranial mesenchyme. J Cell Biol. 2012;196:789-800 pubmed publisher
|
| Koizume S, Ito S, Miyagi E, Hirahara F, Nakamura Y, Sakuma Y, et al. HIF2?-Sp1 interaction mediates a deacetylation-dependent FVII-gene activation under hypoxic conditions in ovarian cancer cells. Nucleic Acids Res. 2012;40:5389-401 pubmed publisher
|
| Yu T, Chen X, Zhang W, Li J, Xu R, Wang T, et al. Krüppel-like factor 4 regulates intestinal epithelial cell morphology and polarity. PLoS ONE. 2012;7:e32492 pubmed publisher
|
| Tsai W, Wang P, Lin S, Wu I, Ko Y, Chen Y, et al. Ser-634 and Ser-636 of Kaposi's Sarcoma-Associated Herpesvirus RTA are Involved in Transactivation and are Potential Cdk9 Phosphorylation Sites. Front Microbiol. 2012;3:60 pubmed publisher
|
| Montegna E, Bhave M, Liu Y, Bhattacharyya D, Glick B. Sec12 binds to Sec16 at transitional ER sites. PLoS ONE. 2012;7:e31156 pubmed publisher
|
| Robinson A, Kwek S, Kenney S. The B-cell specific transcription factor, Oct-2, promotes Epstein-Barr virus latency by inhibiting the viral immediate-early protein, BZLF1. PLoS Pathog. 2012;8:e1002516 pubmed publisher
|
| Tavares L, Dimitrova E, Oxley D, Webster J, Poot R, Demmers J, et al. RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3. Cell. 2012;148:664-78 pubmed publisher
|
| Buscaino A, White S, Houston D, Lejeune E, Simmer F, de Lima Alves F, et al. Raf1 Is a DCAF for the Rik1 DDB1-like protein and has separable roles in siRNA generation and chromatin modification. PLoS Genet. 2012;8:e1002499 pubmed publisher
|
| Ko Y, Tsai W, Wang P, Wu I, Lin S, Chen Y, et al. Suppressive regulation of KSHV RTA with O-GlcNAcylation. J Biomed Sci. 2012;19:12 pubmed publisher
|
| Wen X, Casey Klockow L, Nekorchuk M, Sharifi H, de Noronha C. The HIV1 protein Vpr acts to enhance constitutive DCAF1-dependent UNG2 turnover. PLoS ONE. 2012;7:e30939 pubmed publisher
|
| Vinopal S, Cernohorská M, Sulimenko V, Sulimenko T, Vosecká V, Flemr M, et al. ?-Tubulin 2 nucleates microtubules and is downregulated in mouse early embryogenesis. PLoS ONE. 2012;7:e29919 pubmed publisher
|
| Wolf A, Beuerlein K, Eckart C, Weiser H, Dickkopf B, Müller H, et al. Identification and functional characterization of novel phosphorylation sites in TAK1-binding protein (TAB) 1. PLoS ONE. 2011;6:e29256 pubmed publisher
|
| Kern F, Sarg B, Stasyk T, Hess D, Lindner H. The Nogo receptor 2 is a novel substrate of Fbs1. Biochem Biophys Res Commun. 2012;417:977-81 pubmed publisher
|
| Schulz D, Vassen L, Chow K, McWhirter S, Amin R, Moroy T, et al. Gfi1b negatively regulates Rag expression directly and via the repression of FoxO1. J Exp Med. 2012;209:187-99 pubmed publisher
|
| Malik S, Chaurasia P, Lahudkar S, Uprety B, Bhaumik S. Rad26p regulates the occupancy of histone H2A-H2B dimer at the active genes in vivo. Nucleic Acids Res. 2012;40:3348-63 pubmed publisher
|
| Dickerman B, White C, Chevalier C, Nalesso V, Charles C, Fouchécourt S, et al. Missense mutation in the second RNA binding domain reveals a role for Prkra (PACT/RAX) during skull development. PLoS ONE. 2011;6:e28537 pubmed publisher
|
| Lund N, Milev M, Wong R, Sanmuganantham T, Woolaway K, Chabot B, et al. Differential effects of hnRNP D/AUF1 isoforms on HIV-1 gene expression. Nucleic Acids Res. 2012;40:3663-75 pubmed publisher
|
| Martin L, Rainey M, Santocanale C, Gardner L. Hypoxic activation of ATR and the suppression of the initiation of DNA replication through cdc6 degradation. Oncogene. 2012;31:4076-84 pubmed publisher
|
| Gombos I, Crul T, Piotto S, Güngör B, Török Z, Balogh G, et al. Membrane-lipid therapy in operation: the HSP co-inducer BGP-15 activates stress signal transduction pathways by remodeling plasma membrane rafts. PLoS ONE. 2011;6:e28818 pubmed publisher
|
| Sperka T, Geissler K, Merkel U, Scholl I, Rubio I, Herrlich P, et al. Activation of Ras requires the ERM-dependent link of actin to the plasma membrane. PLoS ONE. 2011;6:e27511 pubmed publisher
|
| Moser B, Chang Y, Kosti J, Nakamura T. Tel1ATM and Rad3ATR kinases promote Ccq1-Est1 interaction to maintain telomeres in fission yeast. Nat Struct Mol Biol. 2011;18:1408-13 pubmed publisher
|
| Yu J, Feng Q, Ruan Y, Komers R, Kiviat N, Bomsztyk K. Microplate-based platform for combined chromatin and DNA methylation immunoprecipitation assays. BMC Mol Biol. 2011;12:49 pubmed publisher
|
| Lukic Z, Hausmann S, Sebastian S, Rucci J, Sastri J, Robia S, et al. TRIM5? associates with proteasomal subunits in cells while in complex with HIV-1 virions. Retrovirology. 2011;8:93 pubmed publisher
|
| Ahlenstiel C, Lim H, Cooper D, Ishida T, Kelleher A, Suzuki K. Direct evidence of nuclear Argonaute distribution during transcriptional silencing links the actin cytoskeleton to nuclear RNAi machinery in human cells. Nucleic Acids Res. 2012;40:1579-95 pubmed publisher
|
| Ahmed N, Zeng M, Sinha I, Polin L, Wei W, Rathinam C, et al. The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation. Nat Immunol. 2011;12:1176-83 pubmed publisher
|
| Mendoza Villanueva D, Zeef L, Shore P. Metastatic breast cancer cells inhibit osteoblast differentiation through the Runx2/CBF?-dependent expression of the Wnt antagonist, sclerostin. Breast Cancer Res. 2011;13:R106 pubmed publisher
|
| Thastrup J, Rafiqi F, Vitari A, Pozo Guisado E, Deak M, Mehellou Y, et al. SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation. Biochem J. 2012;441:325-37 pubmed publisher
|
| Theunissen T, Costa Y, Radzisheuskaya A, van Oosten A, Lavial F, Pain B, et al. Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain. Development. 2011;138:4853-65 pubmed publisher
|
| Hjerpe R, Thomas Y, Chen J, Zemla A, Curran S, Shpiro N, et al. Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes. Biochem J. 2012;441:927-36 pubmed publisher
|
| Huang L, Li Y, Chen C. Flexible catalytic site conformations implicated in modulation of HIV-1 protease autoprocessing reactions. Retrovirology. 2011;8:79 pubmed publisher
|
| Sun H, Ou N, Wang S, Liu W, Cheng T, Shr S, et al. Novel nucleotide and amino acid covariation between the 5'UTR and the NS2/NS3 proteins of hepatitis C virus: bioinformatic and functional analyses. PLoS ONE. 2011;6:e25530 pubmed publisher
|
| Chai Z, Goodenough D, Paul D. Cx50 requires an intact PDZ-binding motif and ZO-1 for the formation of functional intercellular channels. Mol Biol Cell. 2011;22:4503-12 pubmed publisher
|
| Moree B, Meyer C, Fuller C, Straight A. CENP-C recruits M18BP1 to centromeres to promote CENP-A chromatin assembly. J Cell Biol. 2011;194:855-71 pubmed publisher
|
| Carrière L, Graziani S, Alibert O, Ghavi Helm Y, Boussouar F, Humbertclaude H, et al. Genomic binding of Pol III transcription machinery and relationship with TFIIS transcription factor distribution in mouse embryonic stem cells. Nucleic Acids Res. 2012;40:270-83 pubmed publisher
|
| Braun F, Bertin Ciftci J, Gallouet A, Millour J, Juin P. Serum-nutrient starvation induces cell death mediated by Bax and Puma that is counteracted by p21 and unmasked by Bcl-x(L) inhibition. PLoS ONE. 2011;6:e23577 pubmed publisher
|
| Ratzka A, Baron O, Grothe C. FGF-2 deficiency does not influence FGF ligand and receptor expression during development of the nigrostriatal system. PLoS ONE. 2011;6:e23564 pubmed publisher
|
| Kwon C, Cheng P, King I, Andersen P, Shenje L, Nigam V, et al. Notch post-translationally regulates ?-catenin protein in stem and progenitor cells. Nat Cell Biol. 2011;13:1244-51 pubmed publisher
|
| Kula A, Guerra J, Knezevich A, Kleva D, Myers M, Marcello A. Characterization of the HIV-1 RNA associated proteome identifies Matrin 3 as a nuclear cofactor of Rev function. Retrovirology. 2011;8:60 pubmed publisher
|
| Ma L, Jarman A. Dilatory is a Drosophila protein related to AZI1 (CEP131) that is located at the ciliary base and required for cilium formation. J Cell Sci. 2011;124:2622-30 pubmed publisher
|
| Felle M, Joppien S, Nemeth A, Diermeier S, Thalhammer V, Dobner T, et al. The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1. Nucleic Acids Res. 2011;39:8355-65 pubmed publisher
|
| Zhu X, Zhang Y, Bjornsdottir G, Liu Z, Quan A, Costanzo M, et al. Histone modifications influence mediator interactions with chromatin. Nucleic Acids Res. 2011;39:8342-54 pubmed publisher
|
| Kivimäe S, Yang X, Cheyette B. All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases. BMC Biochem. 2011;12:33 pubmed publisher
|
| Chen K, Luo Z, Zheng S. Gallus Heat shock cognate protein 70, a novel binding partner of Apoptin. Virol J. 2011;8:324 pubmed publisher
|
| Beckmann J, Vitobello A, Ferralli J, Kenzelmann Broz D, Rijli F, Chiquet Ehrismann R. Human teneurin-1 is a direct target of the homeobox transcription factor EMX2 at a novel alternate promoter. BMC Dev Biol. 2011;11:35 pubmed publisher
|
| Yu J, Li X, Wang Y, Li B, Li H, Li Y, et al. PDlim2 selectively interacts with the PDZ binding motif of highly pathogenic avian H5N1 influenza A virus NS1. PLoS ONE. 2011;6:e19511 pubmed publisher
|
| Cheong C, Lon Ng P, Ponnampalam R, Tsai H, Bourque G, Lufkin T. In silico tandem affinity purification refines an Oct4 interaction list. Stem Cell Res Ther. 2011;2:26 pubmed publisher
|
| Lazaridis I, Charalampopoulos I, Alexaki V, Avlonitis N, Pediaditakis I, Efstathopoulos P, et al. Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. PLoS Biol. 2011;9:e1001051 pubmed publisher
|
| Roberts D, Pronobis M, Poulton J, Waldmann J, Stephenson E, Hanna S, et al. Deconstructing the ßcatenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signaling. Mol Biol Cell. 2011;22:1845-63 pubmed publisher
|
| Gassman N, Clodfelter J, McCauley A, Bonin K, Salsbury F, Scarpinato K. Cooperative nuclear localization sequences lend a novel role to the N-terminal region of MSH6. PLoS ONE. 2011;6:e17907 pubmed publisher
|
| Heideker J, Prudden J, Perry J, Tainer J, Boddy M. SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1-mediated DNA damage and genome instability. PLoS Genet. 2011;7:e1001320 pubmed publisher
|
| Rakovic A, Grünewald A, Kottwitz J, Brüggemann N, Pramstaller P, Lohmann K, et al. Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts. PLoS ONE. 2011;6:e16746 pubmed publisher
|
| Wang D, Li Y, Wu C, Liu Y. PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression. PLoS ONE. 2011;6:e17048 pubmed publisher
|
| Lui T, Lacroix C, Ahmed S, Goldenberg S, Leach C, Daulat A, et al. The ubiquitin-specific protease USP34 regulates axin stability and Wnt/?-catenin signaling. Mol Cell Biol. 2011;31:2053-65 pubmed publisher
|
| Lesbats P, Botbol Y, Chevereau G, Vaillant C, Calmels C, Arneodo A, et al. Functional coupling between HIV-1 integrase and the SWI/SNF chromatin remodeling complex for efficient in vitro integration into stable nucleosomes. PLoS Pathog. 2011;7:e1001280 pubmed publisher
|
| Huang Y, Chen L, Zhou Y, Liu H, Yang J, Liu Z, et al. UXT-V1 protects cells against TNF-induced apoptosis through modulating complex II formation. Mol Biol Cell. 2011;22:1389-97 pubmed publisher
|
| Keady B, Le Y, Pazour G. IFT20 is required for opsin trafficking and photoreceptor outer segment development. Mol Biol Cell. 2011;22:921-30 pubmed publisher
|
| Hartig J, Forstemann K. Loqs-PD and R2D2 define independent pathways for RISC generation in Drosophila. Nucleic Acids Res. 2011;39:3836-51 pubmed publisher
|
| Mittal S, Aslam A, Doidge R, Medica R, Winkler G. The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence. Mol Biol Cell. 2011;22:748-58 pubmed publisher
|
| Pokrzywa M, Dacklin I, Vestling M, Hultmark D, Lundgren E, Cantera R. Uptake of aggregating transthyretin by fat body in a Drosophila model for TTR-associated amyloidosis. PLoS ONE. 2010;5:e14343 pubmed publisher
|
| Hirota T, Lee J, Lewis W, Zhang E, Breton G, Liu X, et al. High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKI? as a clock regulatory kinase. PLoS Biol. 2010;8:e1000559 pubmed publisher
|
| Cao F, Chen Y, Cierpicki T, Liu Y, Basrur V, Lei M, et al. An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain. PLoS ONE. 2010;5:e14102 pubmed publisher
|
| King O, Li X, Sakurai M, Kawamura A, Rose N, Ng S, et al. Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors. PLoS ONE. 2010;5:e15535 pubmed publisher
|
| Cox J, Mallanna S, Luo X, Rizzino A. Sox2 uses multiple domains to associate with proteins present in Sox2-protein complexes. PLoS ONE. 2010;5:e15486 pubmed publisher
|
| Yu W, Qiu Z, Gao N, Wang L, Cui H, Qian Y, et al. PAK1IP1, a ribosomal stress-induced nucleolar protein, regulates cell proliferation via the p53-MDM2 loop. Nucleic Acids Res. 2011;39:2234-48 pubmed publisher
|
| Prizan Ravid A, Elis E, Laham Karam N, Selig S, Ehrlich M, Bacharach E. The Gag cleavage product, p12, is a functional constituent of the murine leukemia virus pre-integration complex. PLoS Pathog. 2010;6:e1001183 pubmed publisher
|
| Anderson H, Kagansky A, Wardle J, Rappsilber J, Allshire R, Whitehall S. Silencing mediated by the Schizosaccharomyces pombe HIRA complex is dependent upon the Hpc2-like protein, Hip4. PLoS ONE. 2010;5:e13488 pubmed publisher
|
| He X, Ni Y, Wang Y, Romigh T, Eng C. Naturally occurring germline and tumor-associated mutations within the ATP-binding motifs of PTEN lead to oxidative damage of DNA associated with decreased nuclear p53. Hum Mol Genet. 2011;20:80-9 pubmed publisher
|
| Desmet R, Diesis E, Drobecq H, Rouanet C, Chemlal K, Debrie A, et al. In situ chemical modification of peptide microarrays: application to the study of the antibody responses to methylated antigens. Methods Mol Biol. 2010;669:135-45 pubmed publisher
|
| Kuny C, Chinchilla K, Culbertson M, Kalejta R. Cyclin-dependent kinase-like function is shared by the beta- and gamma- subset of the conserved herpesvirus protein kinases. PLoS Pathog. 2010;6:e1001092 pubmed publisher
|
| Rorke E, Adhikary G, Jans R, Crish J, Eckert R. AP1 factor inactivation in the suprabasal epidermis causes increased epidermal hyperproliferation and hyperkeratosis but reduced carcinogen-dependent tumor formation. Oncogene. 2010;29:5873-82 pubmed publisher
|
| Kramer M, Boeck J, Reichenbach D, Kaether C, Schreiber S, Platzer M, et al. NOD2-C2 - a novel NOD2 isoform activating NF-kappaB in a muramyl dipeptide-independent manner. BMC Res Notes. 2010;3:224 pubmed publisher
|
| Munday D, Emmott E, Surtees R, Lardeau C, Wu W, Duprex W, et al. Quantitative proteomic analysis of A549 cells infected with human respiratory syncytial virus. Mol Cell Proteomics. 2010;9:2438-59 pubmed publisher
|
| Peng S, Lai Y, Huang H, Huang H, Huang Y. A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons. Nucleic Acids Res. 2010;38:7446-57 pubmed publisher
|
| Sakamoto K, Huang B, Iwasaki K, Hailemariam K, Ninomiya Tsuji J, Tsuji Y. Regulation of genotoxic stress response by homeodomain-interacting protein kinase 2 through phosphorylation of cyclic AMP response element-binding protein at serine 271. Mol Biol Cell. 2010;21:2966-74 pubmed publisher
|
| Foldynova Trantirkova S, Sekyrova P, Tmejová K, Brumovská E, Bernatik O, Blankenfeldt W, et al. Breast cancer-specific mutations in CK1epsilon inhibit Wnt/beta-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration. Breast Cancer Res. 2010;12:R30 pubmed publisher
|
| Nillegoda N, Theodoraki M, Mandal A, Mayo K, Ren H, Sultana R, et al. Ubr1 and Ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins. Mol Biol Cell. 2010;21:2102-16 pubmed publisher
|
| Kwon H, Jeong K, Hwang E, Park J, Pak Y. A novel domain of caveolin-2 that controls nuclear targeting: regulation of insulin-specific ERK activation and nuclear translocation by caveolin-2. J Cell Mol Med. 2011;15:888-908 pubmed publisher
|
| Fang X, Lu Q, Emoto K, Adler P. The Drosophila Fry protein interacts with Trc and is highly mobile in vivo. BMC Dev Biol. 2010;10:40 pubmed publisher
|
| Bayne E, White S, Kagansky A, Bijos D, Sanchez Pulido L, Hoe K, et al. Stc1: a critical link between RNAi and chromatin modification required for heterochromatin integrity. Cell. 2010;140:666-77 pubmed publisher
|
| Tao Y, Xi S, Briones V, Muegge K. Lsh mediated RNA polymerase II stalling at HoxC6 and HoxC8 involves DNA methylation. PLoS ONE. 2010;5:e9163 pubmed publisher
|
| Subramanian L, Nakamura T. A kinase-independent role for the Rad3(ATR)-Rad26(ATRIP) complex in recruitment of Tel1(ATM) to telomeres in fission yeast. PLoS Genet. 2010;6:e1000839 pubmed publisher
|
| Metzner M, Schuh W, Roth E, Jack H, Wabl M. Two forms of activation-induced cytidine deaminase differing in their ability to bind agarose. PLoS ONE. 2010;5:e8883 pubmed publisher
|
| Rajkovic M, Iwen K, Hofmann P, Harneit A, Weitzel J. Functional cooperation between CREM and GCNF directs gene expression in haploid male germ cells. Nucleic Acids Res. 2010;38:2268-78 pubmed publisher
|
| Follit J, Li L, Vucica Y, Pazour G. The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence. J Cell Biol. 2010;188:21-8 pubmed publisher
|
| He S, McPhaul C, Li J, Garuti R, Kinch L, Grishin N, et al. A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis. J Biol Chem. 2010;285:6706-15 pubmed publisher
|
| Matsuda S, Matsuda Y, D ADAMIO L. CD74 interacts with APP and suppresses the production of Abeta. Mol Neurodegener. 2009;4:41 pubmed publisher
|
| van De Sluis B, Groot A, Vermeulen J, van der Wall E, van Diest P, Wijmenga C, et al. COMMD1 Promotes pVHL and O2-Independent Proteolysis of HIF-1alpha via HSP90/70. PLoS ONE. 2009;4:e7332 pubmed publisher
|
| Medendorp K, van Groningen J, Vreede L, Hetterschijt L, van den Hurk W, de Bruijn D, et al. The mitotic arrest deficient protein MAD2B interacts with the small GTPase RAN throughout the cell cycle. PLoS ONE. 2009;4:e7020 pubmed publisher
|
| Kunnev D, Ivanov I, Ionov Y. Par-3 partitioning defective 3 homolog (C. elegans) and androgen-induced prostate proliferative shutoff associated protein genes are mutationally inactivated in prostate cancer cells. BMC Cancer. 2009;9:318 pubmed publisher
|
| Moser B, Subramanian L, Khair L, Chang Y, Nakamura T. Fission yeast Tel1(ATM) and Rad3(ATR) promote telomere protection and telomerase recruitment. PLoS Genet. 2009;5:e1000622 pubmed publisher
|
| Souplet V, Roux C, Melnyk O. Peptide microarrays on bisphenol A polycarbonate. Methods Mol Biol. 2009;570:287-97 pubmed publisher
|
| Chen Y, Deng Y, Zhang J, Yang L, Xie X, Xu T. GDI-1 preferably interacts with Rab10 in insulin-stimulated GLUT4 translocation. Biochem J. 2009;422:229-35 pubmed publisher
|
| D Ambrogio A, Buratti E, Stuani C, Guarnaccia C, Romano M, Ayala Y, et al. Functional mapping of the interaction between TDP-43 and hnRNP A2 in vivo. Nucleic Acids Res. 2009;37:4116-26 pubmed publisher
|
| Dowen R, Engel J, Shao F, Ecker J, Dixon J. A family of bacterial cysteine protease type III effectors utilizes acylation-dependent and -independent strategies to localize to plasma membranes. J Biol Chem. 2009;284:15867-79 pubmed publisher
|
| Hausmann S, Marq J, Tapparel C, Kolakofsky D, Garcin D. RIG-I and dsRNA-induced IFNbeta activation. PLoS ONE. 2008;3:e3965 pubmed publisher
|
| Ku M, Koche R, Rheinbay E, Mendenhall E, Endoh M, Mikkelsen T, et al. Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains. PLoS Genet. 2008;4:e1000242 pubmed publisher
|
| Ariumi Y, Kuroki M, Dansako H, Abe K, Ikeda M, Wakita T, et al. The DNA damage sensors ataxia-telangiectasia mutated kinase and checkpoint kinase 2 are required for hepatitis C virus RNA replication. J Virol. 2008;82:9639-46 pubmed publisher
|
| Hodge J, Stanewsky R. Function of the Shaw potassium channel within the Drosophila circadian clock. PLoS ONE. 2008;3:e2274 pubmed publisher
|
| Hendrickson D, Hogan D, Herschlag D, Ferrell J, Brown P. Systematic identification of mRNAs recruited to argonaute 2 by specific microRNAs and corresponding changes in transcript abundance. PLoS ONE. 2008;3:e2126 pubmed publisher
|
| Owen L, Kowalewski A, Lessnick S. EWS/FLI mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcoma. PLoS ONE. 2008;3:e1965 pubmed publisher
|
| Tsaadon L, Kaplan Kraicer R, Shalgi R. Myristoylated alanine-rich C kinase substrate, but not Ca2+/calmodulin-dependent protein kinase II, is the mediator in cortical granules exocytosis. Reproduction. 2008;135:613-24 pubmed publisher
|
| Zhao R, Kakihara Y, Gribun A, Huen J, Yang G, Khanna M, et al. Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation. J Cell Biol. 2008;180:563-78 pubmed publisher
|
| Li C, Chen H, Hu L, Xing Y, Sasaki T, Villosis M, et al. Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2. BMC Mol Biol. 2008;9:11 pubmed publisher
|
| Potts P, Yu H. The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins. Nat Struct Mol Biol. 2007;14:581-90 pubmed
|
| Urban J, Vogel J. Translational control and target recognition by Escherichia coli small RNAs in vivo. Nucleic Acids Res. 2007;35:1018-37 pubmed
|
| Weinberger L, Shenk T. An HIV feedback resistor: auto-regulatory circuit deactivator and noise buffer. PLoS Biol. 2007;5:e9 pubmed
|