product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-Fibronectin antibody produced in mouse
catalog :
F0916
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
IST-4
reactivity :
human
application :
immunohistochemistry, immunocytochemistry
more info or order :
citations: 44
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; loading ...; fig 1h
Chen H, Wei Z, Sun J, Bhattacharya A, Savage D, Serda R, et al. A recellularized human colon model identifies cancer driver genes. Nat Biotechnol. 2016;34:845-51 pubmed publisher
  • immunocytochemistry; human; 1:100; fig 3
Sanz Garcia A, Stojkovic M, Escobedo Lucea C. Growth of Human Pluripotent Stem Cells Using Functional Human Extracellular Matrix. Methods Mol Biol. 2016;1307:39-60 pubmed publisher
Xie W, Liu X, Chen Q, Ma M, Yang X, Gong B, et al. Silencing of the long non-coding RNA GHET1 inhibits cell proliferation and migration of renal cell carcinoma through epithelial-mesenchymal transition. Oncol Lett. 2019;17:3173-3180 pubmed publisher
Boel N, Hunter M, Edkins A. LRP1 is required for novobiocin-mediated fibronectin turnover. Sci Rep. 2018;8:11438 pubmed publisher
Di Modugno F, Spada S, Palermo B, Visca P, Iapicca P, Di Carlo A, et al. hMENA isoforms impact NSCLC patient outcome through fibronectin/β1 integrin axis. Oncogene. 2018;37:5605-5617 pubmed publisher
Dhanani K, Samson W, Edkins A. Fibronectin is a stress responsive gene regulated by HSF1 in response to geldanamycin. Sci Rep. 2017;7:17617 pubmed publisher
Kearns V, Tasker J, Zhuola -, Akhtar R, Bachhuka A, Vasilev K, et al. The formation of a functional retinal pigment epithelium occurs on porous polytetrafluoroethylene substrates independently of the surface chemistry. J Mater Sci Mater Med. 2017;28:124 pubmed publisher
Grudzien Nogalska E, Jiao X, Song M, Hart R, Kiledjian M. Nudt3 is an mRNA decapping enzyme that modulates cell migration. RNA. 2016;22:773-81 pubmed publisher
Chen P, Qin L, Baeyens N, Li G, Afolabi T, Budatha M, et al. Endothelial-to-mesenchymal transition drives atherosclerosis progression. J Clin Invest. 2015;125:4514-28 pubmed publisher
Arnold S, Loomans H, Ketova T, Andl C, Clark P, Zijlstra A. Urinary oncofetal ED-A fibronectin correlates with poor prognosis in patients with bladder cancer. Clin Exp Metastasis. 2016;33:29-44 pubmed publisher
Bernard K, Logsdon N, Ravi S, Xie N, Persons B, Rangarajan S, et al. Metabolic Reprogramming Is Required for Myofibroblast Contractility and Differentiation. J Biol Chem. 2015;290:25427-38 pubmed publisher
Brockmann T, Brockmann C, Maier A, Gundlach E, Schroeter J, Bertelmann E, et al. Descemet Membrane Endothelial Keratoplasty for Graft Failure After Descemet Stripping Endothelial Keratoplasty: Clinical Results and Histopathologic Findings. JAMA Ophthalmol. 2015;133:813-9 pubmed publisher
Nagao R, Ouyang Y, Keller R, Lee C, Suggs L, Schmidt C. Preservation of Capillary-beds in Rat Lung Tissue Using Optimized Chemical Decellularization. J Mater Chem B. 2013;1:4801-4808 pubmed
Hsu I, Parkinson L, Shen Y, Toro A, Brown T, Zhao H, et al. Serpina3n accelerates tissue repair in a diabetic mouse model of delayed wound healing. Cell Death Dis. 2014;5:e1458 pubmed publisher
François D, Venisse L, Marchal Somme J, Jandrot Perrus M, Crestani B, Arocas V, et al. Increased expression of protease nexin-1 in fibroblasts during idiopathic pulmonary fibrosis regulates thrombin activity and fibronectin expression. Lab Invest. 2014;94:1237-46 pubmed publisher
Le T, Karmouty Quintana H, Melicoff E, Le T, Weng T, Chen N, et al. Blockade of IL-6 Trans signaling attenuates pulmonary fibrosis. J Immunol. 2014;193:3755-68 pubmed publisher
Lan A, Zhang J, Xiao Z, Peng X, Qi Y, Du J. Akt2 is involved in loss of epithelial cells and renal fibrosis following unilateral ureteral obstruction. PLoS ONE. 2014;9:e105451 pubmed publisher
Wong M, Saad S, Zhang J, Gross S, Jarolimek W, Schilter H, et al. Semicarbazide-sensitive amine oxidase (SSAO) inhibition ameliorates kidney fibrosis in a unilateral ureteral obstruction murine model. Am J Physiol Renal Physiol. 2014;307:F908-16 pubmed publisher
Sabatier L, Djokic J, Hubmacher D, Dzafik D, Nelea V, Reinhardt D. Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly. FEBS Lett. 2014;588:2890-7 pubmed publisher
Duitman J, Ruela de Sousa R, Shi K, de Boer O, Borensztajn K, Florquin S, et al. Protease activated receptor-1 deficiency diminishes bleomycin-induced skin fibrosis. Mol Med. 2014;20:410-6 pubmed publisher
Klug T, Henriksen J, Rusan M, Fuursted K, Krogfelt K, Ovesen T, et al. Antibody development to Fusobacterium necrophorum in patients with peritonsillar abscess. Eur J Clin Microbiol Infect Dis. 2014;33:1733-9 pubmed publisher
Wang M, Ren D, Guo W, Wang Z, Huang S, Du H, et al. Loss of miR-100 enhances migration, invasion, epithelial-mesenchymal transition and stemness properties in prostate cancer cells through targeting Argonaute 2. Int J Oncol. 2014;45:362-72 pubmed publisher
Kolar M, Kingham P, Novikova L, Wiberg M, Novikov L. The therapeutic effects of human adipose-derived stem cells in a rat cervical spinal cord injury model. Stem Cells Dev. 2014;23:1659-74 pubmed publisher
Brockmann T, Brockmann C, Maier A, Schroeter J, Pleyer U, Bertelmann E, et al. Clinicopathology of graft detachment after Descemet's membrane endothelial keratoplasty. Acta Ophthalmol. 2014;92:e556-61 pubmed publisher
Hunter M, O Hagan K, Kenyon A, Dhanani K, Prinsloo E, Edkins A. Hsp90 binds directly to fibronectin (FN) and inhibition reduces the extracellular fibronectin matrix in breast cancer cells. PLoS ONE. 2014;9:e86842 pubmed publisher
Chen P, Qin L, Barnes C, Charisse K, Yi T, Zhang X, et al. FGF regulates TGF-? signaling and endothelial-to-mesenchymal transition via control of let-7 miRNA expression. Cell Rep. 2012;2:1684-96 pubmed publisher
Guo Q, Lu X, Xue Y, Zheng H, Zhao X, Zhao H. A new candidate substrate for cell-matrix adhesion study: the acellular human amniotic matrix. J Biomed Biotechnol. 2012;2012:306083 pubmed publisher
Freeman W, VanGuilder H, Guidone E, Krystal J, Grant K, Vrana K. Plasma proteomic alterations in non-human primates and humans after chronic alcohol self-administration. Int J Neuropsychopharmacol. 2011;14:899-911 pubmed publisher
Rizvi I, Celli J, Evans C, Abu Yousif A, Muzikansky A, Pogue B, et al. Synergistic enhancement of carboplatin efficacy with photodynamic therapy in a three-dimensional model for micrometastatic ovarian cancer. Cancer Res. 2010;70:9319-28 pubmed publisher
Haddad Weber M, Prager P, Kunz M, Seefried L, Jakob F, Murray M, et al. BMP12 and BMP13 gene transfer induce ligamentogenic differentiation in mesenchymal progenitor and anterior cruciate ligament cells. Cytotherapy. 2010;12:505-13 pubmed publisher
Escobedo Lucea C, Stojkovic M. Growth of human embryonic stem cells using derivates of human fibroblasts. Methods Mol Biol. 2010;584:55-69 pubmed publisher
Stratman A, Malotte K, Mahan R, Davis M, Davis G. Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation. Blood. 2009;114:5091-101 pubmed publisher
Di Girolamo N, Bosch M, Zamora K, Coroneo M, Wakefield D, Watson S. A contact lens-based technique for expansion and transplantation of autologous epithelial progenitors for ocular surface reconstruction. Transplantation. 2009;87:1571-8 pubmed publisher
Castelletti F, Donadelli R, Banterla F, Hildebrandt F, Zipfel P, Bresin E, et al. Mutations in FN1 cause glomerulopathy with fibronectin deposits. Proc Natl Acad Sci U S A. 2008;105:2538-43 pubmed publisher
Lei Q, Zhang H, Zhao B, Zha Z, Bai F, Pei X, et al. TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway. Mol Cell Biol. 2008;28:2426-36 pubmed publisher
Rastogi S, Mishra S, Zaca V, Alesh I, Gupta R, Goldstein S, et al. Effect of long-term monotherapy with the aldosterone receptor blocker eplerenone on cytoskeletal proteins and matrix metalloproteinases in dogs with heart failure. Cardiovasc Drugs Ther. 2007;21:415-22 pubmed
Pelliccione F, Cordeschi G, Bocchio M, Mancini M, Sagone P, Francavilla F, et al. Immunophenotypical characterization of contractile cells in caput epididymidis of men affected by congenital or post-inflammatory obstructive azoospermia. Mol Hum Reprod. 2005;11:289-94 pubmed
Sekiguchi K, Siri A, Zardi L, Hakomori S. Differences in domain structure between pericellular matrix and plasma fibronectins as revealed by domain-specific antibodies combined with limited proteolysis and S-cyanylation: a preliminary note. Biochem Biophys Res Commun. 1983;116:534-40 pubmed
Zardi L, Carnemolla B, Siri A, Santi L, Accolla R. Somatic cell hybrids producing antibodies specific to human fibronectin. Int J Cancer. 1980;25:325-9 pubmed
Sekiguchi K, Siri A, Zardi L, Hakomori S. Differences in domain structure between human fibronectins isolated from plasma and from culture supernatants of normal and transformed fibroblasts. Studies with domain-specific antibodies. J Biol Chem. 1985;260:5105-14 pubmed
Borsi L, Carnemolla B, Castellani P, Rosellini C, Vecchio D, Allemanni G, et al. Monoclonal antibodies in the analysis of fibronectin isoforms generated by alternative splicing of mRNA precursors in normal and transformed human cells. J Cell Biol. 1987;104:595-600 pubmed
Zardi L, Carnemolla B, Balza E, Borsi L, Castellani P, Rocco M, et al. Elution of fibronectin proteolytic fragments from a hydroxyapatite chromatography column. A simple procedure for the purification of fibronectin domains. Eur J Biochem. 1985;146:571-9 pubmed
Zardi L, Carnemolla B, Siri A, Petersen T, Paolella G, Sebastio G, et al. Transformed human cells produce a new fibronectin isoform by preferential alternative splicing of a previously unobserved exon. EMBO J. 1987;6:2337-42 pubmed
Carnemolla B, Balza E, Siri A, Zardi L, Nicotra M, Bigotti A, et al. A tumor-associated fibronectin isoform generated by alternative splicing of messenger RNA precursors. J Cell Biol. 1989;108:1139-48 pubmed
product information
Catalog Number :
F0916
Product Name :
Monoclonal Anti-Fibronectin antibody produced in mouse
Product Type :
ANTIBODIES - SIAL
Product Group :
Protein & Pathway Technologies
Host Species :
mouse
Clonality :
monoclonal
Conjugation :
unconjugated
Clone Name :
IST-4
Isotype :
IgG1
Product Description :
clone IST-4, ascites fluid
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA