This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Exendin-4
catalog :
E7144
citations: 19
Reference
Bułdak Ł, Machnik G, Skudrzyk E, Bołdys A, Okopień B. The impact of exenatide (a GLP-1 agonist) on markers of inflammation and oxidative stress in normal human astrocytes subjected to various glycemic conditions. Exp Ther Med. 2019;17:2861-2869 pubmed publisher
Liu J, Yang K, Yang J, Xiao W, Le Y, Yu F, et al. Liver-derived fibroblast growth factor 21 mediates effects of glucagon-like peptide-1 in attenuating hepatic glucose output. EBioMedicine. 2019;: pubmed publisher
Eriksson O, Korsgren O, Selvaraju R, Mollaret M, de Boysson Y, Chimienti F, et al. Pancreatic imaging using an antibody fragment targeting the zinc transporter type 8: a direct comparison with radio-iodinated Exendin-4. Acta Diabetol. 2018;55:49-57 pubmed publisher
Zhang Q, Hao J, Li G, Ji X, Yao X, Dong N, et al. Proinflammatory switch from G?s to G?i signaling by Glucagon-like peptide-1 receptor in murine splenic monocyte following burn injury. Inflamm Res. 2018;67:157-168 pubmed publisher
Thomson S, Kashkouli A, Liu Z, Singh P. Renal hemodynamic effects of glucagon-like peptide-1 agonist are mediated by nitric oxide but not prostaglandin. Am J Physiol Renal Physiol. 2017;313:F854-F858 pubmed publisher
Fenske R, Cadena M, Harenda Q, Wienkes H, Carbajal K, Schaid M, et al. The Inhibitory G Protein ?-Subunit, G?z, Promotes Type 1 Diabetes-Like Pathophysiology in NOD Mice. Endocrinology. 2017;158:1645-1658 pubmed publisher
Muhammad A, Xing B, Liu C, Naji A, Ma X, Simmons R, et al. Menin and PRMT5 suppress GLP1 receptor transcript and PKA-mediated phosphorylation of FOXO1 and CREB. Am J Physiol Endocrinol Metab. 2017;313:E148-E166 pubmed publisher
Kim J, Park S, You Y, Ham D, Lee S, Yang H, et al. Suppression of ROS Production by Exendin-4 in PSC Attenuates the High Glucose-Induced Islet Fibrosis. PLoS ONE. 2016;11:e0163187 pubmed publisher
Kumar A, Lo Nigro A, Gysemans C, Cai Q, Esguerra C, Nelson Holte M, et al. Reversal of hyperglycemia by insulin-secreting rat bone marrow- and blastocyst-derived hypoblast stem cell-like cells. PLoS ONE. 2013;8:e63491 pubmed publisher
Bi D, Chen F, Zhang W, Zhou G, Cui L, Liu W, et al. Differentiation of human multipotent dermal fibroblasts into islet-like cell clusters. BMC Cell Biol. 2010;11:46 pubmed publisher
Dong Y, Sui L, Yamaguchi F, Kamitori K, Hirata Y, Suzuki A, et al. Role of phosphatase and tensin homolog in the development of the mammalian auditory system. Neuroreport. 2010;21:731-5 pubmed publisher
Arakawa M, Mita T, Azuma K, Ebato C, Goto H, Nomiyama T, et al. Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4. Diabetes. 2010;59:1030-7 pubmed publisher
Ding X, Saxena N, Lin S, Gupta N, Gupta N, Anania F. Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice. Hepatology. 2006;43:173-81 pubmed
DeFronzo R, Ratner R, Han J, Kim D, Fineman M, Baron A. Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes. Diabetes Care. 2005;28:1092-100 pubmed
Xu G, Stoffers D, Habener J, Bonner Weir S. Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats. Diabetes. 1999;48:2270-6 pubmed
Beak S, Heath M, Small C, Morgan D, Ghatei M, Taylor A, et al. Glucagon-like peptide-1 stimulates luteinizing hormone-releasing hormone secretion in a rodent hypothalamic neuronal cell line. J Clin Invest. 1998;101:1334-41 pubmed
Montrose Rafizadeh C, Yang H, Rodgers B, Beday A, Pritchette L, Eng J. High potency antagonists of the pancreatic glucagon-like peptide-1 receptor. J Biol Chem. 1997;272:21201-6 pubmed
Singh G, Eng J, Raufman J. Use of 125I-[Y39]exendin-4 to characterize exendin receptors on dispersed pancreatic acini and gastric chief cells from guinea pig. Regul Pept. 1994;53:47-59 pubmed
Eng J, Kleinman W, Singh L, Singh G, Raufman J. Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas. J Biol Chem. 1992;267:7402-5 pubmed
product information
Catalog Number :
E7144
Product Name :
Exendin-4
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
≥97%
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA