This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
β-Estradiol 3-(β-D-glucuronide) sodium salt
catalog :
E2127
citations: 25
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O Connor K, Brindle E, Shofer J, Miller R, Klein N, Soules M, et al. Statistical correction for non-parallelism in a urinary enzyme immunoassay. J Immunoassay Immunochem. 2004;25:259-78 pubmed
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Gerk P, Li W, Vore M. Estradiol 3-glucuronide is transported by the multidrug resistance-associated protein 2 but does not activate the allosteric site bound by estradiol 17-glucuronide. Drug Metab Dispos. 2004;32:1139-45 pubmed
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Tohyama O, Imura A, Iwano A, Freund J, Henrissat B, Fujimori T, et al. Klotho is a novel beta-glucuronidase capable of hydrolyzing steroid beta-glucuronides. J Biol Chem. 2004;279:9777-84 pubmed
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Mottino A, Veggi L, Wood M, Román J, Vore M. Biliary secretion of glutathione in estradiol 17beta-D-glucuronide-induced cholestasis. J Pharmacol Exp Ther. 2003;307:306-13 pubmed
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O Connor K, Brindle E, Holman D, Klein N, Soules M, Campbell K, et al. Urinary estrone conjugate and pregnanediol 3-glucuronide enzyme immunoassays for population research. Clin Chem. 2003;49:1139-48 pubmed
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Soars M, Ring B, Wrighton S. The effect of incubation conditions on the enzyme kinetics of udp-glucuronosyltransferases. Drug Metab Dispos. 2003;31:762-7 pubmed
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Tabas L, Dantzig A. A high-throughput assay for measurement of multidrug resistance protein-mediated transport of leukotriene C4 into membrane vesicles. Anal Biochem. 2002;310:61-6 pubmed
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Fisher M, VandenBranden M, Findlay K, Burchell B, Thummel K, Hall S, et al. Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank. Pharmacogenetics. 2000;10:727-39 pubmed
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Panter G, Thompson R, Beresford N, Sumpter J. Transformation of a non-oestrogenic steroid metabolite to an oestrogenically active substance by minimal bacterial activity. Chemosphere. 1999;38:3579-96 pubmed
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Freundl G, Bonnar J, Flynn A, Frank Herrmann P, Kirkmann R, Snowden R. [Contraception per computer. Hormone system persona--results of studies in Germany]. Fortschr Med. 1998;116:47-8 pubmed
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Kanai N, Lu R, Bao Y, Wolkoff A, Vore M, Schuster V. Estradiol 17 beta-D-glucuronide is a high-affinity substrate for oatp organic anion transporter. Am J Physiol. 1996;270:F326-31 pubmed
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Zhu B, Evaristus E, Antoniak S, Sarabia S, Ricci M, Liehr J. Metabolic deglucuronidation and demethylation of estrogen conjugates as a source of parent estrogens and catecholestrogen metabolites in Syrian hamster kidney, a target organ of estrogen-induced tumorigenesis. Toxicol Appl Pharmacol. 1996;136:186-93 pubmed
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Ruoff W, Dziuk P. Absorption and metabolism of estrogens from the stomach and duodenum of pigs. Domest Anim Endocrinol. 1994;11:197-208 pubmed
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Connors S, Vore M. Coregulation of C3-hydroxyl versus C17-hydroxyl glucuronidation of beta-estradiol in pregnancy and after treatment with phenobarbital or ethinyl-estradiol. J Pharmacol Exp Ther. 1988;246:54-9 pubmed
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Rae M, Mole P, Paterson C. Evaluation of urinary oestrogen assays after the menopause and their potential for screening. Clin Chim Acta. 1988;176:71-81 pubmed
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Kan K, Monte M, Parslow R, Coleman R. Oestradiol 17 beta-glucuronide increases tight-junctional permeability in rat liver. Biochem J. 1989;261:297-300 pubmed
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Changchit A, Durham S, Vore M. Characterization of [3H]estradiol-17 beta-(beta-D-glucuronide) binding sites in basolateral and canalicular liver plasma membranes. Biochem Pharmacol. 1990;40:1219-25 pubmed
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Abernathy C, Zimmerman H, Ishak K, Utili R, Gillespie J. Drug-induced cholestasis in the perfused rat liver and its reversal by tauroursodeoxycholate: an ultrastructural study. Proc Soc Exp Biol Med. 1992;199:54-8 pubmed
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product information
Catalog Number :
E2127
Product Name :
β-Estradiol 3-(β-D-glucuronide) sodium salt
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
company information

MilliporeSigma
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