This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Embelin
catalog :
E1406
citations: 27
Reference
Leung D, Nguyen T, Oliver E, Matti J, Alexiadis M, Silke J, et al. Combined PPARγ Activation and XIAP Inhibition as a Potential Therapeutic Strategy for Ovarian Granulosa Cell Tumors. Mol Cancer Ther. 2019;18:364-375 pubmed publisher
Srivastava S, Bhowmick K, Chatterjee S, Basha J, Kundu T, Dhar S. Histone H3K9 acetylation level modulates gene expression and may affect parasite growth in human malaria parasite Plasmodium falciparum. FEBS J. 2014;281:5265-78 pubmed publisher
Park S, Lim S, Jang H, Lee J, Um J, Kim S, et al. Embelin induces apoptosis in human glioma cells through inactivating NF-κB. J Pharmacol Sci. 2013;121:192-9 pubmed
Lin Z, Jensen J, Hong Z, Shi X, Hu L, Andreasen P, et al. Structural insight into inactivation of plasminogen activator inhibitor-1 by a small-molecule antagonist. Chem Biol. 2013;20:253-61 pubmed publisher
Deshmukh P, Gupta V. Embelin accelerates cutaneous wound healing in diabetic rats. J Asian Nat Prod Res. 2013;15:158-65 pubmed publisher
Lu J, Huang Y, Zhao W, Marquez R, Meng X, Li J, et al. PEG-derivatized embelin as a nanomicellar carrier for delivery of paclitaxel to breast and prostate cancers. Biomaterials. 2013;34:1591-600 pubmed publisher
Gandhi G, Stalin A, Balakrishna K, Ignacimuthu S, Paulraj M, Vishal R. Insulin sensitization via partial agonism of PPAR? and glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway by embelin in type 2 diabetic rats. Biochim Biophys Acta. 2013;1830:2243-55 pubmed publisher
Kim S, Kim S, Bae H, Nam D, Lee J, Lee S, et al. Embelin inhibits growth and induces apoptosis through the suppression of Akt/mTOR/S6K1 signaling cascades. Prostate. 2013;73:296-305 pubmed publisher
Huang Y, Lu J, Gao X, Li J, Zhao W, Sun M, et al. PEG-derivatized embelin as a dual functional carrier for the delivery of paclitaxel. Bioconjug Chem. 2012;23:1443-51 pubmed publisher
Radhakrishnan N, Gnanamani A, Prasad N, Mandal A. Inhibition of UVB-induced oxidative damage and apoptotic biochemical changes in human lymphocytes by 2,5-dihydroxy-3-undecyl-1,4-benzoquinone (embelin). Int J Radiat Biol. 2012;88:575-82 pubmed publisher
Allensworth J, Aird K, Aldrich A, Batinic Haberle I, Devi G. XIAP inhibition and generation of reactive oxygen species enhances TRAIL sensitivity in inflammatory breast cancer cells. Mol Cancer Ther. 2012;11:1518-27 pubmed publisher
Danquah M, Duke C, Patil R, Miller D, Mahato R. Combination therapy of antiandrogen and XIAP inhibitor for treating advanced prostate cancer. Pharm Res. 2012;29:2079-91 pubmed publisher
Chaudhari H, Bhandari U, Khanna G. Preventive effect of embelin from embelia ribes on lipid metabolism and oxidative stress in high-fat diet-induced obesity in rats. Planta Med. 2012;78:651-7 pubmed publisher
Che Y, Ye F, Xu R, Qing H, Wang X, Yin F, et al. Co-expression of XIAP and cyclin D1 complex correlates with a poor prognosis in patients with hepatocellular carcinoma. Am J Pathol. 2012;180:1798-807 pubmed publisher
Pandey A, Ojha V. Estimation of Embelin in Embelia tsjeriam-cottam Fruits by HPLC to Standardize Harvesting Time. Indian J Pharm Sci. 2011;73:216-9 pubmed
Gupta R, Sharma A, Sharma M, Gupta R. Antioxidant activity and protection of pancreatic ?-cells by embelin in streptozotocin-induced diabetes. J Diabetes. 2012;4:248-56 pubmed publisher
Hill C, Alexander M, McCullough L, Fitch R. Inhibition of X-linked inhibitor of apoptosis with embelin differentially affects male versus female behavioral outcome following neonatal hypoxia-ischemia in rats. Dev Neurosci. 2011;33:494-504 pubmed publisher
Mahendran S, Badami S, Ravi S, Thippeswamy B, Veerapur V. Synthesis and evaluation of analgesic and anti-inflammatory activities of most active free radical scavenging derivatives of embelin-A structure-activity relationship. Chem Pharm Bull (Tokyo). 2011;59:913-9 pubmed
Thippeswamy B, Nagakannan P, Shivasharan B, Mahendran S, Veerapur V, Badami S. Protective effect of embelin from Embelia ribes Burm. against transient global ischemia-induced brain damage in rats. Neurotox Res. 2011;20:379-86 pubmed publisher
Siegel C, Li J, Liu F, Benashski S, McCullough L. miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia. Proc Natl Acad Sci U S A. 2011;108:11662-7 pubmed publisher
Heo J, Kim H, Kim S, Park K, Park S, Kim S, et al. Embelin suppresses STAT3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase PTEN. Cancer Lett. 2011;308:71-80 pubmed publisher
Kalyan Kumar G, Dhamotharan R, Kulkarni N, Mahat M, Gunasekaran J, Ashfaque M. Embelin reduces cutaneous TNF-? level and ameliorates skin edema in acute and chronic model of skin inflammation in mice. Eur J Pharmacol. 2011;662:63-9 pubmed publisher
Kumar G K, Dhamotharan R -, Kulkarni N, Honnegowda S, Murugesan S -. Embelin ameliorates dextran sodium sulfate-induced colitis in mice. Int Immunopharmacol. 2011;11:724-31 pubmed publisher
Thippeswamy B, Mahendran S, Biradar M, Raj P, Srivastava K, Badami S, et al. Protective effect of embelin against acetic acid induced ulcerative colitis in rats. Eur J Pharmacol. 2011;654:100-5 pubmed publisher
Poojari R, Gupta S, Maru G, Khade B, Bhagwat S. Chemopreventive and hepatoprotective effects of embelin on N-nitrosodiethylamine and carbon tetrachloride induced preneoplasia and toxicity in rat liver. Asian Pac J Cancer Prev. 2010;11:1015-20 pubmed
Li F, Danquah M, Mahato R. Synthesis and characterization of amphiphilic lipopolymers for micellar drug delivery. Biomacromolecules. 2010;11:2610-20 pubmed publisher
Madhavan S, Arimboor R, Arumughan C. RP-HPLC-DAD method for the estimation of embelin as marker in Embelia ribes and its polyherbal formulations. Biomed Chromatogr. 2011;25:600-5 pubmed publisher
product information
Catalog Number :
E1406
Product Name :
Embelin
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥98% (HPLC), powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA