This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
EHNA hydrochloride
catalog :
E114
citations: 48
Reference
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Lesscher H, Bailey A, Vanderschuren L. Genetic Variability in Adenosine Deaminase-Like Contributes to Variation in Alcohol Preference in Mice. Alcohol Clin Exp Res. 2017;41:1271-1279 pubmed publisher
Cristofani R, Crippa V, Rusmini P, Cicardi M, Meroni M, Licata N, et al. Inhibition of retrograde transport modulates misfolded protein accumulation and clearance in motoneuron diseases. Autophagy. 2017;13:1280-1303 pubmed publisher
Eisner C, Kim S, Grill A, Qin Y, Hoerl M, Briggs J, et al. Profound hypothermia after adenosine kinase inhibition in A1AR-deficient mice suggests a receptor-independent effect of intracellular adenosine. Pflugers Arch. 2017;469:339-347 pubmed publisher
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Chen W, Wu Y, Li L, Yang M, Shen L, Liu G, et al. Adenosine accelerates the healing of diabetic ischemic ulcers by improving autophagy of endothelial progenitor cells grown on a biomaterial. Sci Rep. 2015;5:11594 pubmed publisher
Eguchi R, Akao S, Otsuguro K, Yamaguchi S, Ito S. Different mechanisms of extracellular adenosine accumulation by reduction of the external Ca(2+) concentration and inhibition of adenosine metabolism in spinal astrocytes. J Pharmacol Sci. 2015;128:47-53 pubmed publisher
Glotfelty L, Zahs A, Iancu C, Shen L, Hecht G. Microtubules are required for efficient epithelial tight junction homeostasis and restoration. Am J Physiol Cell Physiol. 2014;307:C245-54 pubmed publisher
Xu M, Li X, Xiong J, Xia M, Gulbins E, Zhang Y, et al. Regulation of autophagic flux by dynein-mediated autophagosomes trafficking in mouse coronary arterial myocytes. Biochim Biophys Acta. 2013;1833:3228-3236 pubmed publisher
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Morita H, Murata T, Shimizu K, Okumura K, Inui M, Tagawa T. Characterization of phosphodiesterase 2A in human malignant melanoma PMP cells. Oncol Rep. 2013;29:1275-84 pubmed publisher
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Ivanov A, Matsumura I. The adenosine deaminases of Plasmodium vivax and Plasmodium falciparum exhibit surprising differences in ligand specificity. J Mol Graph Model. 2012;35:43-8 pubmed publisher
Fenton R, Dobson J. Reduced adenosine release from the aged mammalian heart. J Cell Physiol. 2012;227:3709-14 pubmed publisher
Abd Elfattah A, Ding M, Jessen M, Wechsler A. On-pump inhibition of es-ENT1 nucleoside transporter and adenosine deaminase during aortic crossclamping entraps intracellular adenosine and protects against reperfusion injury: role of adenosine A1 receptor. J Thorac Cardiovasc Surg. 2012;144:243-9 pubmed publisher
Kimura N, Okabayashi S, Ono F. Dynein dysfunction disrupts intracellular vesicle trafficking bidirectionally and perturbs synaptic vesicle docking via endocytic disturbances a potential mechanism underlying age-dependent impairment of cognitive function. Am J Pathol. 2012;180:550-61 pubmed publisher
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Burton P, Adams D, Abraham A, Allcock R, Jiang Z, McCahill A, et al. Erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA) blocks differentiation and maintains the expression of pluripotency markers in human embryonic stem cells. Biochem J. 2010;432:575-84 pubmed publisher
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Yamamoto M, Suzuki S, Himeno M. The effects of dynein inhibition on the autophagic pathway in glioma cells. Neuropathology. 2010;30:1-6 pubmed publisher
Tsai N, Tsui Y, Wei L. Dynein motor contributes to stress granule dynamics in primary neurons. Neuroscience. 2009;159:647-56 pubmed publisher
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Kayhan N, Funke B, Conzelmann L, Winkler H, Hofer S, Steppan J, et al. The adenosine deaminase inhibitor erythro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: a prospective, randomised laboratory investigation. Crit Care. 2008;12:R125 pubmed publisher
Wu C, Wong T, Wu X, Sheppy E, Zhang L. Adenosine as an endogenous regulating factor of hippocampal sharp waves. Hippocampus. 2009;19:205-20 pubmed publisher
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Kinoshita T, Tada T, Nakanishi I. Conformational change of adenosine deaminase during ligand-exchange in a crystal. Biochem Biophys Res Commun. 2008;373:53-7 pubmed publisher
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product information
Catalog Number :
E114
Product Name :
EHNA hydrochloride
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥98% (HPLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA