Doigneaux C, Pedley A, Mistry I, Papayova M, Benkovic S, Tavassoli A. Hypoxia drives the assembly of the multienzyme purinosome complex. J Biol Chem. 2020;295:9551-9566 pubmed publisher

Di Tano M, Raucci F, Vernieri C, Caffa I, Buono R, Fanti M, et al. Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers. Nat Commun. 2020;11:2332 pubmed publisher

Pahlow S, Orasch T, Žukovskaja O, Bocklitz T, Haas H, Weber K. Rapid detection of the aspergillosis biomarker triacetylfusarinine C using interference-enhanced Raman spectroscopy. Anal Bioanal Chem. 2020;412:6351-6360 pubmed publisher

Zhang Y, Fan B, Pang Y, Shen W, Wang X, Zhao C, et al. Neuroprotective effect of deferoxamine on erastininduced ferroptosis in primary cortical neurons. Neural Regen Res. 2020;15:1539-1545 pubmed publisher

Fine J, Kosyakovsky J, Baillargeon A, Tokarev J, Cooner J, Svitak A, et al. Intranasal deferoxamine can improve memory in healthy C57 mice, suggesting a partially non-disease-specific pathway of functional neurologic improvement. Brain Behav. 2020;10:e01536 pubmed publisher

Mursaleen L, Somavarapu S, Zariwala M. Deferoxamine and Curcumin Loaded Nanocarriers Protect Against Rotenone-Induced Neurotoxicity. J Parkinsons Dis. 2020;10:99-111 pubmed publisher

Dekens D, De Deyn P, Sap F, Eisel U, Naudé P. Iron chelators inhibit amyloid-β-induced production of lipocalin 2 in cultured astrocytes. Neurochem Int. 2020;132:104607 pubmed publisher

Jiang T, Cheng H, Su J, Wang X, Wang Q, Chu J, et al. Gastrodin protects against glutamate-induced ferroptosis in HT-22 cells through Nrf2/HO-1 signaling pathway. Toxicol In Vitro. 2020;62:104715 pubmed publisher

Hadidi L, Constantin J, Dalisson B, Vieira D, Drager J, Harvey E, et al. Biodegradable hypoxia biomimicry microspheres for bone tissue regeneration. J Biomater Appl. 2020;34:1028-1037 pubmed publisher

Yoo H, Park S, Nam M, Kang J, Kim K, Yeo J, et al. A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells. Cell Metab. 2019;: pubmed publisher

Yambire K, Rostosky C, Watanabe T, Pacheu Grau D, Torres Odio S, Sánchez Guerrero A, et al. Impaired lysosomal acidification triggers iron deficiency and inflammation in vivo. elife. 2019;8: pubmed publisher

Su L, Jiang X, Yang C, Zhang J, Chen B, Li Y, et al. Pannexin 1 mediates ferroptosis that contributes to renal ischemia/reperfusion injury. J Biol Chem. 2019;294:19395-19404 pubmed publisher

Nobuta H, Yang N, Ng Y, Marro S, Sabeur K, Chavali M, et al. Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation. Cell Stem Cell. 2019;25:531-541.e6 pubmed publisher

Han D, Schomacher L, Schüle K, Mallick M, Musheev M, Karaulanov E, et al. NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress. elife. 2019;8: pubmed publisher

Kong Y, Hu L, Lu K, Wang Y, Xie Y, Gao L, et al. Ferroportin downregulation promotes cell proliferation by modulating the Nrf2-miR-17-5p axis in multiple myeloma. Cell Death Dis. 2019;10:624 pubmed publisher

Baumgarten S, Bryant J, Sinha A, Reyser T, Preiser P, Dedon P, et al. Transcriptome-wide dynamics of extensive m6A mRNA methylation during Plasmodium falciparum blood-stage development. Nat Microbiol. 2019;4:2246-2259 pubmed publisher

Yoshida M, Minagawa S, Araya J, Sakamoto T, Hara H, Tsubouchi K, et al. Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis. Nat Commun. 2019;10:3145 pubmed publisher

Jing X, Wang X, Zhang T, Zhu W, Fang Y, Wu H, et al. Cell cycle-dependent phosphorylation of PRPS1 fuels nucleotide synthesis and promotes tumorigenesis. Cancer Res. 2019;: pubmed publisher

Lakhal Littleton S, Crosby A, Frise M, Mohammad G, Carr C, Loick P, et al. Intracellular iron deficiency in pulmonary arterial smooth muscle cells induces pulmonary arterial hypertension in mice. Proc Natl Acad Sci U S A. 2019;: pubmed publisher

Balogh E, Tóth A, Mehes G, Trencsenyi G, Paragh G, Jeney V. Hypoxia Triggers Osteochondrogenic Differentiation of Vascular Smooth Muscle Cells in an HIF-1 (Hypoxia-Inducible Factor 1)-Dependent and Reactive Oxygen Species-Dependent Manner. Arterioscler Thromb Vasc Biol. 2019;39:1088-1099 pubmed publisher

Lu B, Chen X, Hong Y, Zhu H, He Q, Yang B, et al. Identification of PRDX6 as a regulator of ferroptosis. Acta Pharmacol Sin. 2019;: pubmed publisher

Shvartsman M, Bilican S, Lancrin C. Iron deficiency disrupts embryonic haematopoiesis but not the endothelial to haematopoietic transition. Sci Rep. 2019;9:6414 pubmed publisher

Sohoni S, Ghosh P, Wang T, Kalainayakan S, Vidal C, Dey S, et al. Elevated Heme Synthesis and Uptake Underpin Intensified Oxidative Metabolism and Tumorigenic Functions in Non-Small Cell Lung Cancer Cells. Cancer Res. 2019;79:2511-2525 pubmed publisher

Welzel L, Twele F, Schidlitzki A, Töllner K, Klein P, Loscher W. Network pharmacology for antiepileptogenesis: Tolerability and neuroprotective effects of novel multitargeted combination treatments in nonepileptic vs. post-status epilepticus mice. Epilepsy Res. 2019;151:48-66 pubmed publisher

Lang J, Zhao X, Wang X, Zhao Y, Li Y, Zhao R, et al. Targeted Co-delivery of the Iron Chelator Deferoxamine and a HIF1α Inhibitor Impairs Pancreatic Tumor Growth. ACS Nano. 2019;13:2176-2189 pubmed publisher

Fonseca J, Moradi F, Maddalena L, Ferreira Tollstadius B, Selim S, Stuart J. Resveratrol integrates metabolic and growth effects in PC3 prostate cancer cells-involvement of prolyl hydroxylase and hypoxia inducible factor-1. Oncol Lett. 2019;17:697-705 pubmed publisher

Ali M, Sadhu B, Boda A, Tiwari N, Das A, Musharaf Ali S, et al. Thorium decorporation efficacy of rationally-selected biocompatible compounds with relevance to human application. J Hazard Mater. 2019;365:952-961 pubmed publisher

Sui X, Zhang R, Liu S, Duan T, Zhai L, Zhang M, et al. RSL3 Drives Ferroptosis Through GPX4 Inactivation and ROS Production in Colorectal Cancer. Front Pharmacol. 2018;9:1371 pubmed publisher

Hassannia B, Wiernicki B, Ingold I, Qu F, Van Herck S, Tyurina Y, et al. Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma. J Clin Invest. 2018;128:3341-3355 pubmed publisher

O Leary B, Houwen F, Johnson C, Allen B, Mezhir J, Berg D, et al. Pharmacological Ascorbate as an Adjuvant for Enhancing Radiation-Chemotherapy Responses in Gastric Adenocarcinoma. Radiat Res. 2018;189:456-465 pubmed publisher

Wang J, Niu Y, Zhang C, Chen Y. A micro-plate colorimetric assay for rapid determination of trace zinc in animal feed, pet food and drinking water by ion masking and statistical partitioning correction. Food Chem. 2018;245:337-345 pubmed publisher

Liu X, Zhang T, Li X, Zhao G, Xie F. Effects of 2-amino-9H-pyrido[2,3-b]indole (A?C) metabolic bio-activation on oxidative DNA damage in human hepatoma G2 (HepG2) cells. Toxicol Mech Methods. 2017;:1-29 pubmed publisher

Weis S, Carlos A, Moita M, Singh S, Blankenhaus B, Cardoso S, et al. Metabolic Adaptation Establishes Disease Tolerance to Sepsis. Cell. 2017;169:1263-1275.e14 pubmed publisher

Gan E, Cheong W, Chan K, Ong E, Chai X, Tan H, et al. Hypoxia enhances antibody-dependent dengue virus infection. EMBO J. 2017;36:1348-1363 pubmed publisher

Kerins M, Vashisht A, Liang B, Duckworth S, Praslicka B, WOHLSCHLEGEL J, et al. Fumarate Mediates a Chronic Proliferative Signal in Fumarate Hydratase-Inactivated Cancer Cells by Increasing Transcription and Translation of Ferritin Genes. Mol Cell Biol. 2017;37: pubmed publisher

Roman M, Decker E, Goddard J. Retaining Oxidative Stability of Emulsified Foods by Novel Nonmigratory Polyphenol Coated Active Packaging. J Agric Food Chem. 2016;64:5574-82 pubmed publisher

Völlger L, Akong Moore K, Cox L, Goldmann O, Wang Y, Schäfer S, et al. Iron-chelating agent desferrioxamine stimulates formation of neutrophil extracellular traps (NETs) in human blood-derived neutrophils. Biosci Rep. 2016;36: pubmed publisher

Nobles C, Clark J, Green S, Maresso A. A dual component heme biosensor that integrates heme transport and synthesis in bacteria. J Microbiol Methods. 2015;118:7-17 pubmed publisher

Zielke R, Wierzbicki I, Baarda B, Sikora A. The Neisseria gonorrhoeae Obg protein is an essential ribosome-associated GTPase and a potential drug target. BMC Microbiol. 2015;15:129 pubmed publisher

Li Y, Liu Y, Chew S, Tay M, Salido M, Teo J, et al. Complete Genome Sequence and Transcriptomic Analysis of the Novel Pathogen Elizabethkingia anophelis in Response to Oxidative Stress. Genome Biol Evol. 2015;7:1676-85 pubmed publisher

Wang W, Luo S, Xia M, Mao Y, Zhou X, Jiang P, et al. Analysis of the oxidative damage of DNA, RNA, and their metabolites induced by hyperglycemia and related nephropathy in Sprague Dawley rats. Free Radic Res. 2015;49:1199-209 pubmed publisher

Zhang T, Zhao G, Li X, Xie F, Liu H, Xie J. Genotoxic and oxidative stress effects of 2-amino-9H-pyrido[2,3-b]indole in human hepatoma G2 (HepG2) and human lung alveolar epithelial (A549) cells. Toxicol Mech Methods. 2015;25:212-22 pubmed publisher

Ahlqvist K, Leoncini S, Pecorelli A, Wortmann S, Ahola S, Forsström S, et al. MtDNA mutagenesis impairs elimination of mitochondria during erythroid maturation leading to enhanced erythrocyte destruction. Nat Commun. 2015;6:6494 pubmed publisher

Metherel A, Stark K. Cryopreservation prevents iron-initiated highly unsaturated fatty acid loss during storage of human blood on chromatography paper at -20°C. J Nutr. 2015;145:654-60 pubmed publisher

Lakhal Littleton S, Wolna M, Carr C, Miller J, Christian H, Ball V, et al. Cardiac ferroportin regulates cellular iron homeostasis and is important for cardiac function. Proc Natl Acad Sci U S A. 2015;112:3164-9 pubmed publisher

Miyake S, Muramatsu R, Hamaguchi M, Yamashita T. Prolyl hydroxylase regulates axonal rewiring and motor recovery after traumatic brain injury. Cell Death Dis. 2015;6:e1638 pubmed publisher

Sidarovich V, Adami V, Gatto P, Greco V, Tebaldi T, Tonini G, et al. Translational downregulation of HSP90 expression by iron chelators in neuroblastoma cells. Mol Pharmacol. 2015;87:513-24 pubmed publisher

Meadowcroft M, Peters D, Dewal R, Connor J, Yang Q. The effect of iron in MRI and transverse relaxation of amyloid-beta plaques in Alzheimer's disease. NMR Biomed. 2015;28:297-305 pubmed publisher

Fontaine K, Sanchez E, Camarda R, Lagunoff M. Dengue virus induces and requires glycolysis for optimal replication. J Virol. 2015;89:2358-66 pubmed publisher

Curran C, Carrillo E, Ponik S, Keely P. Collagen density regulates xenobiotic and hypoxic response of mammary epithelial cells. Environ Toxicol Pharmacol. 2015;39:114-24 pubmed publisher

Fang G, Zhu C, Dionysiou D, Gao J, Zhou D. Mechanism of hydroxyl radical generation from biochar suspensions: Implications to diethyl phthalate degradation. Bioresour Technol. 2015;176:210-7 pubmed publisher

Ma M, Meszaros L, Paterson B, Berry D, Cooper M, Ma Y, et al. Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with (89)Zr(4+): comparison with desferrioxamine-B. Dalton Trans. 2015;44:4884-900 pubmed publisher

Biville F, Brézillon C, Giorgini D, Taha M. Pyrophosphate-mediated iron acquisition from transferrin in Neisseria meningitidis does not require TonB activity. PLoS ONE. 2014;9:e107612 pubmed publisher

Alta E, Goswami D, Machini M, Silvestre D, Nomura C, Espósito B. Desferrioxamine-caffeine (DFCAF) as a cell permeant moderator of the oxidative stress caused by iron overload. Biometals. 2014;27:1351-60 pubmed publisher

Rodríguez Cotto R, Ortiz Martínez M, Rivera Ramírez E, Mateus V, Amaral B, Jimenez Velez B, et al. Particle pollution in Rio de Janeiro, Brazil: increase and decrease of pro-inflammatory cytokines IL-6 and IL-8 in human lung cells. Environ Pollut. 2014;194:112-120 pubmed publisher

Fernández Blanco C, Font G, Ruiz M. Oxidative stress of alternariol in Caco-2 cells. Toxicol Lett. 2014;229:458-64 pubmed publisher

Biesuz R, Emma G, Milanese C, Dacarro G, Taglietti A, Nurchi V, et al. Novel DFO-SAM on mesoporous silica for iron sensing. Part I. Synthesis optimization and characterization of the material. Analyst. 2014;139:3932-9 pubmed publisher

Chen W, Hu Q, Xia X, Liang C, Liu H, Zhang Q, et al. Rapamycin enhances cetuximab cytotoxicity by inhibiting mTOR-mediated drug resistance in mesenchymal hepatoma cells. Cancer Biol Ther. 2014;15:992-9 pubmed publisher

Guo X, Shi Y, Sheng J, Wang F. A novel hyaluronidase produced by Bacillus sp. A50. PLoS ONE. 2014;9:e94156 pubmed publisher

Le Marechal C, Jardin J, Jan G, Even S, Pulido C, Guibert J, et al. Staphylococcus aureus seroproteomes discriminate ruminant isolates causing mild or severe mastitis. Vet Res. 2011;42:35 pubmed publisher

Smith D, Kitner J, Norbeck A, Clauss T, Lipton M, Schwalbach M, et al. Transcriptional and translational regulatory responses to iron limitation in the globally distributed marine bacterium Candidatus pelagibacter ubique. PLoS ONE. 2010;5:e10487 pubmed publisher

Li H, Swiercz R, Englander E. Elevated metals compromise repair of oxidative DNA damage via the base excision repair pathway: implications of pathologic iron overload in the brain on integrity of neuronal DNA. J Neurochem. 2009;110:1774-83 pubmed publisher

McGiven J, Sawyer J, Perrett L, Brew S, Commander N, Fisher A, et al. A new homogeneous assay for high throughput serological diagnosis of brucellosis in ruminants. J Immunol Methods. 2008;337:7-15 pubmed publisher

Fernandez Real J, Moreno J, Ricart W. Circulating retinol-binding protein-4 concentration might reflect insulin resistance-associated iron overload. Diabetes. 2008;57:1918-25 pubmed publisher

Kruck T, Percy M, Lukiw W. Metal sulfate-mediated induction of pathogenic genes and repression by phenyl butyl nitrone and Feralex-G. Neuroreport. 2008;19:245-9 pubmed publisher

Sanchez Elsner T, Botella L, Velasco B, Corbi A, Attisano L, Bernabeu C. Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression. J Biol Chem. 2001;276:38527-35 pubmed

Fukuchi K, Tomoyasu S, Nakamaki T, Tsuruoka N, Gomi K. DNA damage induces p21 protein expression by inhibiting ubiquitination in ML-1 cells. Biochim Biophys Acta. 1998;1404:405-11 pubmed

Leardi A, Caraglia M, Selleri C, Pepe S, Pizzi C, Notaro R, et al. Desferioxamine increases iron depletion and apoptosis induced by ara-C of human myeloid leukaemic cells. Br J Haematol. 1998;102:746-52 pubmed

Chenoufi N, Baffet G, Drenou B, Cariou S, Desille M, Clement B, et al. Deferoxamine arrests in vitro the proliferation of porcine hepatocyte in G1 phase of the cell cycle. Liver. 1998;18:60-6 pubmed

An W, Kanekal M, Simon M, Maltepe E, Blagosklonny M, Neckers L. Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha. Nature. 1998;392:405-8 pubmed

Porreca E, Ucchino S, Di Febbo C, Di Bartolomeo N, Angelucci D, Napolitano A, et al. Antiproliferative effect of desferrioxamine on vascular smooth muscle cells in vitro and in vivo. Arterioscler Thromb. 1994;14:299-304 pubmed

Fukuchi K, Tomoyasu S, Tsuruoka N, Gomi K. Iron deprivation-induced apoptosis in HL-60 cells. FEBS Lett. 1994;350:139-42 pubmed