This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Danazol
catalog :
D8399
citations: 66
Reference
Baxevanis F, Kuiper J, Fotaki N. Strategic drug analysis in fed-state gastric biorelevant media based on drug physicochemical properties. Eur J Pharm Biopharm. 2018;127:326-341 pubmed publisher
Chen X, Stoneburner K, Ladika M, Kuo T, Kalantar T. High-Throughput Raman Spectroscopy Screening of Excipients for the Stabilization of Amorphous Drugs. Appl Spectrosc. 2015;69:1271-80 pubmed publisher
Mosgaard M, Sassene P, Mu H, Rades T, Müllertz A. Development of a high-throughput in vitro intestinal lipolysis model for rapid screening of lipid-based drug delivery systems. Eur J Pharm Biopharm. 2015;94:493-500 pubmed publisher
Rainville P, Murphy J, Tomany M, Wilson I, Smith N, Evans C, et al. An integrated ceramic, micro-fluidic device for the LC/MS/MS analysis of pharmaceuticals in plasma. Analyst. 2015;140:5546-56 pubmed publisher
Goldman J, Leeder J, van Haandel L, Pearce R. In Vitro Hepatic Oxidative Biotransformation of Trimethoprim. Drug Metab Dispos. 2015;43:1372-80 pubmed publisher
Lee E, Wu Z, Shon J, Liu K. Danazol Inhibits Cytochrome P450 2J2 Activity in a Substrate-independent Manner. Drug Metab Dispos. 2015;43:1250-3 pubmed publisher
Khoshakhlagh P, Johnson R, Langguth P, Nawroth T, Schmueser L, Hellmann N, et al. Fasted-state simulated intestinal fluid "FaSSIF-C", a cholesterol containing intestinal model medium for in vitro drug delivery development. J Pharm Sci. 2015;104:2213-24 pubmed publisher
Mathias N, Xu Y, Vig B, Kestur U, Saari A, CRISON J, et al. Food Effect in Humans: Predicting the Risk Through In Vitro Dissolution and In Vivo Pharmacokinetic Models. AAPS J. 2015;17:988-98 pubmed publisher
Cho S, Park H, Lee J, Do J, Heo S, Jo J, et al. Determination of anabolic-androgenic steroid adulterants in counterfeit drugs by UHPLC-MS/MS. J Pharm Biomed Anal. 2015;111:138-46 pubmed publisher
Bartonkova I, Novotna A, Dvorak Z. Novel stably transfected human reporter cell line AIZ-AR as a tool for an assessment of human androgen receptor transcriptional activity. PLoS ONE. 2015;10:e0121316 pubmed publisher
Mierzejewska K, Borkowska S, Suszyńska E, Suszynska M, Poniewierska Baran A, Maj M, et al. Hematopoietic stem/progenitor cells express several functional sex hormone receptors-novel evidence for a potential developmental link between hematopoiesis and primordial germ cells. Stem Cells Dev. 2015;24:927-37 pubmed publisher
Komasaka T, Fujimura H, Tagawa T, Sugiyama A, Kitano Y. Practical method for preparing nanosuspension formulations for toxicology studies in the discovery stage: formulation optimization and in vitro/in vivo evaluation of nanosized poorly water-soluble compounds. Chem Pharm Bull (Tokyo). 2014;62:1073-82 pubmed
Anby M, Nguyen T, Yeap Y, Feeney O, Williams H, Benameur H, et al. An in vitro digestion test that reflects rat intestinal conditions to probe the importance of formulation digestion vs first pass metabolism in Danazol bioavailability from lipid based formulations. Mol Pharm. 2014;11:4069-83 pubmed publisher
Liu G, Suzuki K, Li M, Qu J, Montserrat N, Tarantino C, et al. Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs. Nat Commun. 2014;5:4330 pubmed publisher
Nanda M, Singh U, Wilmot J, Bernstein J. A cross-sectional questionnaire assessing patient and physician use of short-term prophylaxis for hereditary angioedema. Ann Allergy Asthma Immunol. 2014;113:198-203 pubmed publisher
Kan C, Singh A, Stafforini D, Azhar S, Liu J. Arachidonic acid downregulates acyl-CoA synthetase 4 expression by promoting its ubiquitination and proteasomal degradation. J Lipid Res. 2014;55:1657-67 pubmed publisher
Anby M, Williams H, Feeney O, Edwards G, Benameur H, Pouton C, et al. Non-linear increases in danazol exposure with dose in older vs. younger beagle dogs: the potential role of differences in bile salt concentration, thermodynamic activity, and formulation digestion. Pharm Res. 2014;31:1536-52 pubmed publisher
Devalapally H, Zhou F, McDade J, GOLOVERDA G, Owen A, Hidalgo I, et al. Optimization of PEGylated nanoemulsions for improved pharmacokinetics of BCS class II compounds. Drug Deliv. 2015;22:467-74 pubmed publisher
Dertlioğlu S, Cicek D, Yesilova Y. A rare cause of recurrent abdominal pain: three familial cases with hereditary angioedema. Indian J Dermatol Venereol Leprol. 2013;79:105-7 pubmed publisher
Guerrero Hernández A, Oropeza Rechy G, Gómez García E. [Risk factors associated, diagnostic methods and treatment for endometriosis, used in clinical service endometriosis gynecology Hospital General de Mexico (2009-2011)]. Ginecol Obstet Mex. 2012;80:637-43 pubmed
Chan W, Berlin N, Sussman G. Management of hereditary angioedema with C1-inhibitor concentrate during two successive pregnancies. Int J Gynaecol Obstet. 2013;120:189-90 pubmed publisher
Devraj R, Williams H, Warren D, Mullertz A, Porter C, Pouton C. In vitro digestion testing of lipid-based delivery systems: calcium ions combine with fatty acids liberated from triglyceride rich lipid solutions to form soaps and reduce the solubilization capacity of colloidal digestion products. Int J Pharm. 2013;441:323-33 pubmed publisher
Gernsheimer T, James A, Stasi R. How I treat thrombocytopenia in pregnancy. Blood. 2013;121:38-47 pubmed publisher
Abu Hashim H. Medical treatment of idiopathic heavy menstrual bleeding. What is new? An evidence based approach. Arch Gynecol Obstet. 2013;287:251-60 pubmed publisher
Kou T, Watanabe M, Yazumi S. Hepatic failure during anabolic steroid therapy. Gastroenterology. 2012;143:e11-2 pubmed publisher
Williams H, Anby M, Sassene P, Kleberg K, Bakala N Goma J, Calderone M, et al. Toward the establishment of standardized in vitro tests for lipid-based formulations. 2. The effect of bile salt concentration and drug loading on the performance of type I, II, IIIA, IIIB, and IV formulations during in vitro digestion. Mol Pharm. 2012;9:3286-300 pubmed publisher
Farkas H, Zotter Z, Csuka D, Szabo E, Nébenfűhrer Z, Temesszentandrási G, et al. Short-term prophylaxis in hereditary angioedema due to deficiency of the C1-inhibitor--a long-term survey. Allergy. 2012;67:1586-93 pubmed publisher
Zhou H, Fu R, Wang H, Zhou F, Li H, Zhou Z, et al. Immune thrombocytopenia in the elderly: clinical course in 525 patients from a single center in China. Ann Hematol. 2013;92:79-87 pubmed publisher
Parmentier J, Thomas N, Mullertz A, Fricker G, Rades T. Exploring the fate of liposomes in the intestine by dynamic in vitro lipolysis. Int J Pharm. 2012;437:253-63 pubmed publisher
Farkas H, Csuka D, Toth F, Kőszegi L, Varga L. Successful pregnancy outcome after treatment with C1-inhibitor concentrate in a patient with hereditary angioedema and a history of four miscarriages. Eur J Obstet Gynecol Reprod Biol. 2012;165:366-7 pubmed publisher
Van Speybroeck M, Williams H, Nguyen T, Anby M, Porter C, Augustijns P. Incomplete desorption of liquid excipients reduces the in vitro and in vivo performance of self-emulsifying drug delivery systems solidified by adsorption onto an inorganic mesoporous carrier. Mol Pharm. 2012;9:2750-60 pubmed publisher
Bork K. Current management options for hereditary angioedema. Curr Allergy Asthma Rep. 2012;12:273-80 pubmed publisher
Seyer Hansen M, Kruse C. [Limited effect of gonadotrophin-releasing hormone analogues for patients with endometriosis]. Ugeskr Laeger. 2012;174:1671-3 pubmed
Williams H, Sassene P, Kleberg K, Bakala N Goma J, Calderone M, Jannin V, et al. Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: method parameterization and comparison of in vitro digestion profiles across a range of representative formulations. J Pharm Sci. 2012;101:3360-80 pubmed publisher
Flower A, Liu J, Lewith G, Little P, Li Q. Chinese herbal medicine for endometriosis. Cochrane Database Syst Rev. 2012;:CD006568 pubmed publisher
Uchiyama M, Jin X, Zhang Q, Amano A, Watanabe T, Niimi M. Induction of regulatory CD4? cells and prolongation of survival of fully allogeneic murine cardiac grafts by danazol. Transplant Proc. 2012;44:1067-9 pubmed publisher
Thomas G, Rael L, Bar Or R, Mains C, Slone D, Boyd S, et al. Biphasic effect of danazol on human vascular endothelial cell permeability and f-actin cytoskeleton dynamics. Biochem Biophys Res Commun. 2012;421:707-12 pubmed publisher
Vertzoni M, Markopoulos C, Symillides M, Goumas C, Imanidis G, Reppas C. Luminal lipid phases after administration of a triglyceride solution of danazol in the fed state and their contribution to the flux of danazol across Caco-2 cell monolayers. Mol Pharm. 2012;9:1189-98 pubmed publisher
Andres E, Mecili M, Fothergill H, Zimmer J, Vogel T, Maloisel F. Gender-related analysis of the clinical presentation, treatment response and outcome in patients with immune thrombocytopenia. Presse Med. 2012;41:e426-31 pubmed publisher
Brown J, Kives S, Akhtar M. Progestagens and anti-progestagens for pain associated with endometriosis. Cochrane Database Syst Rev. 2012;:CD002122 pubmed publisher
Hosotte M, Jarlot S, Luyasu S, Kanny G. [Quincke's oedema or angioedema]. Rev Prat. 2012;62:242-4 pubmed
Florio P, Filippeschi M, Imperatore A, Mereu L, Franchini M, Calzolari S, et al. The practicability and surgeons' subjective experiences with vaginal danazol before an operative hysteroscopy. Steroids. 2012;77:528-33 pubmed publisher
Lee C, Jones J, Katayama J, Kaspera R, Jiang Y, Freiwald S, et al. Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity. Drug Metab Dispos. 2012;40:943-51 pubmed publisher
Letchumanan P, Thumboo J. Danazol in the treatment of systemic lupus erythematosus: a qualitative systematic review. Semin Arthritis Rheum. 2011;40:298-306 pubmed publisher
Ke L, Yang K, Li J, Li C. Danazol for uterine fibroids. Cochrane Database Syst Rev. 2009;:CD007692 pubmed publisher
Craig T. Appraisal of danazol prophylaxis for hereditary angioedema. Allergy Asthma Proc. 2008;29:225-31 pubmed publisher
Selak V, Farquhar C, Prentice A, Singla A. Danazol for pelvic pain associated with endometriosis. Cochrane Database Syst Rev. 2007;:CD000068 pubmed
Beaumont H, Augood C, Duckitt K, Lethaby A. Danazol for heavy menstrual bleeding. Cochrane Database Syst Rev. 2007;:CD001017 pubmed
Hughes E, Brown J, Tiffin G, Vandekerckhove P. Danazol for unexplained subfertility. Cochrane Database Syst Rev. 2007;:CD000069 pubmed
Andres E, Zimmer J, Noel E, Kaltenbach G, Koumarianou A, Maloisel F. Idiopathic thrombocytopenic purpura: a retrospective analysis in 139 patients of the influence of age on the response to corticosteroids, splenectomy and danazol. Drugs Aging. 2003;20:841-6 pubmed
Beaumont H, Augood C, Duckitt K, Lethaby A. Danazol for heavy menstrual bleeding. Cochrane Database Syst Rev. 2002;:CD001017 pubmed
Selak V, Farquhar C, Prentice A, Singla A. Danazol for pelvic pain associated with endometriosis. Cochrane Database Syst Rev. 2001;:CD000068 pubmed
Igarashi M, Fukuda M, Ando A, Miyasaka M, Taguchi H, Yoshida M, et al. [Local administration of danazol on pelvic endometriosis and uterine adenomyosis]. Nihon Rinsho. 2001;59 Suppl 1:153-6 pubmed
Furuya K, Murakami M, Mizumoto Y, Tokuoka S, Makimura N, Nagata I. [Low-dose danazol therapy in endometriosis]. Nihon Rinsho. 2001;59 Suppl 1:145-51 pubmed
Tamaya T. [Danazol--up-to-date aspect for endometriosis]. Nihon Rinsho. 2001;59 Suppl 1:139-44 pubmed
Hughes E, Tiffin G, Vandekerckhove P. Danazol for unexplained infertilty. Cochrane Database Syst Rev. 2000;:CD000069 pubmed
Selak V, Farquhar C, Prentice A, Singla A. Danazol for pelvic pain associated with endometriosis. Cochrane Database Syst Rev. 2000;:CD000068 pubmed
Borras Blasco J, Rosique Robles J, Peris Martí J, Navarro Ruiz J, Gonzalez Delgado M, Conesa García V. Possible cyclosporin-danazol interaction in a patient with aplastic anaemia. Am J Hematol. 1999;62:63-4 pubmed
Tanaka T, Umesaki N, Chen H, Mizuno K, Ogita S. Danazol effects on human endometrial cells in vitro. Clin Exp Obstet Gynecol. 1999;26:67-70 pubmed
Katsuki Y, Nobukata H, Ishikawa T, Hamada Y, Sato M, Shibutani Y. Effects of dienogest (a synthetic steroid) on coagulation, fibrinolysis, and platelet aggregation in female monkeys. Toxicol Lett. 1998;98:105-13 pubmed
Saygili U, Uslu T, Yorukoglu K, Dogan E, Erten O. Estrogen and progesterone receptor manipulations in castrated rat uterus models and the clinical adaptation. Eur J Gynaecol Oncol. 1998;19:410-4 pubmed
Webb A. Gestagens, danazol and antiprogestogen in emergency contraception. Eur J Contracept Reprod Health Care. 1997;2:127-9 pubmed
Farkas H, Gyeney L, Gidófalvy E, Fust G, Varga L. [Efficacy of short-term danazol treatment in hereditary angioneurotic edema patients undergoing maxillofacial and dental surgical procedures]. Fogorv Sz. 1998;91:171-8 pubmed
Malaguarnera M, Santangelo N, Motta M, Pistone G. Danazol induced cholestasis: pathogenetic hypothesis. Panminerva Med. 1997;39:244-7 pubmed
Miller E. The use of danazol in the therapy of immune-mediated disease of dogs. Semin Vet Med Surg (Small Anim). 1997;12:167-9 pubmed
Harrington W, Kolodny L, Horstman L, Jy W, Ahn Y. Danazol for paroxysmal nocturnal hemoglobinuria. Am J Hematol. 1997;54:149-54 pubmed
product information
Catalog Number :
D8399
Product Name :
Danazol
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥98%
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA