This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Domoic acid
catalog :
D6152
citations: 70
Reference
Van Acker E, De Rijcke M, Asselman J, Beck I, Huysman S, Vanhaecke L, et al. Aerosolizable Marine Phycotoxins and Human Health Effects: In Vitro Support for the Biogenics Hypothesis. Mar Drugs. 2020;18: pubmed publisher
Gaidin S, Zinchenko V, Teplov I, Tuleukhanov S, Kosenkov A. Epileptiform activity promotes decreasing of Ca2+ conductivity of NMDARs, AMPARs, KARs, and voltage-gated calcium channels in Mg2+-free model. Epilepsy Res. 2019;158:106224 pubmed publisher
Bretherton L, Hillhouse J, Bacosa H, Setta S, Genzer J, Kamalanathan M, et al. Growth dynamics and domoic acid production of Pseudo-nitzschia sp. in response to oil and dispersant exposure. Harmful Algae. 2019;86:55-63 pubmed publisher
Lefebvre K, Yakes B, Frame E, Kendrick P, Shum S, Isoherranen N, et al. Discovery of a Potential Human Serum Biomarker for Chronic Seafood Toxin Exposure Using an SPR Biosensor. Toxins (Basel). 2019;11: pubmed publisher
Selander E, Berglund E, Engstrom P, Berggren F, Eklund J, Harðardóttir S, et al. Copepods drive large-scale trait-mediated effects in marine plankton. Sci Adv. 2019;5:eaat5096 pubmed publisher
Ventoso P, Pazos A, Pérez Parallé M, Blanco J, Triviño J, Sanchez J. RNA-Seq Transcriptome Profiling of the Queen Scallop (Aequipecten opercularis) Digestive Gland after Exposure to Domoic Acid-Producing Pseudo-nitzschia. Toxins (Basel). 2019;11: pubmed publisher
Ujevic I, Roje Busatto R, Ezgeta Balić D. Comparison of amnesic, paralytic and lipophilic toxins profiles in cockle (Acanthocardia tuberculata) and smooth clam (Callista chione) from the central Adriatic Sea (Croatia). Toxicon. 2019;159:32-37 pubmed publisher
Shum S, Kirkwood J, Jing J, Petroff R, Crouthamel B, Grant K, et al. Validated HPLC-MS/MS Method To Quantify Low Levels of Domoic Acid in Plasma and Urine after Subacute Exposure. ACS Omega. 2018;3:12079-12088 pubmed publisher
Sanchis A, Salvador J, Campbell K, Elliott C, Shelver W, Li Q, et al. Fluorescent microarray for multiplexed quantification of environmental contaminants in seawater samples. Talanta. 2018;184:499-506 pubmed publisher
Bradley J, Luithardt H, Metea M, Strock C. In Vitro Screening for Seizure Liability Using Microelectrode Array Technology. Toxicol Sci. 2018;163:240-253 pubmed publisher
Snyder C, Yu L, Ngo T, Sheinson D, Zhu Y, Tseng M, et al. In vitro assessment of chemotherapy-induced neuronal toxicity. Toxicol In Vitro. 2018;50:109-123 pubmed publisher
Pérez Gómez A, Cabrera García D, Warm D, Marini A, Salas Puig J, Fernández Sánchez M, et al. Selective Enhancement of Domoic Acid Toxicity in Primary Cultures of Cerebellar Granule Cells by Lowering Extracellular Na+ Concentration. Toxicol Sci. 2017;: pubmed publisher
Frank C, Brown J, Wallace K, Mundy W, Shafer T. From the Cover: Developmental Neurotoxicants Disrupt Activity in Cortical Networks on Microelectrode Arrays: Results of Screening 86 Compounds During Neural Network Formation. Toxicol Sci. 2017;160:121-135 pubmed publisher
Motaghinejad M, Motevalian M, Fatima S, Beiranvand T, Mozaffari S. Topiramate via NMDA, AMPA/kainate, GABAA and Alpha2 receptors and by modulation of CREB/BDNF and Akt/GSK3 signaling pathway exerts neuroprotective effects against methylphenidate-induced neurotoxicity in rats. J Neural Transm (Vienna). 2017;124:1369-1387 pubmed publisher
Ramya E, Kumar G, Anand T, Anilakumar K. Modulatory effects of Terminalia arjuna against domoic acid induced toxicity in Caco-2 cell line. Cytotechnology. 2017;69:725-739 pubmed publisher
O Halloran C, Silver M, Lahiff M, COLFORD J. Respiratory Problems Associated with Surfing in Coastal Waters. Ecohealth. 2017;14:40-47 pubmed publisher
Vassallo A, Chiappalone M, De Camargos Lopes R, Scelfo B, Novellino A, Defranchi E, et al. A multi-laboratory evaluation of microelectrode array-based measurements of neural network activity for acute neurotoxicity testing. Neurotoxicology. 2017;60:280-292 pubmed publisher
Jansen R, Mahakena S, de Haas M, Borst P, van de Wetering K. ATP-binding Cassette Subfamily C Member 5 (ABCC5) Functions as an Efflux Transporter of Glutamate Conjugates and Analogs. J Biol Chem. 2015;290:30429-40 pubmed publisher
Wallace K, Strickland J, Valdivia P, Mundy W, Shafer T. A multiplexed assay for determination of neurotoxicant effects on spontaneous network activity and viability from microelectrode arrays. Neurotoxicology. 2015;49:79-85 pubmed publisher
Zhang W, Yan Z, Gao J, Tong P, Liu W, Zhang L. Metal-organic framework UiO-66 modified magnetite@silica core-shell magnetic microspheres for magnetic solid-phase extraction of domoic acid from shellfish samples. J Chromatogr A. 2015;1400:10-8 pubmed publisher
Hiolski E, Kendrick P, Frame E, Myers M, Bammler T, Beyer R, et al. Chronic low-level domoic acid exposure alters gene transcription and impairs mitochondrial function in the CNS. Aquat Toxicol. 2014;155:151-9 pubmed publisher
Rojas A, Gueorguieva P, Lelutiu N, Quan Y, Shaw R, Dingledine R. The prostaglandin EP1 receptor potentiates kainate receptor activation via a protein kinase C pathway and exacerbates status epilepticus. Neurobiol Dis. 2014;70:74-89 pubmed publisher
Barra L, Ruggiero M, Sarno D, Montresor M, Kooistra W. Strengths and weaknesses of microarray approaches to detect Pseudo-nitzschia species in the field. Environ Sci Pollut Res Int. 2013;20:6705-18 pubmed publisher
Sison Mangus M, Jiang S, Tran K, Kudela R. Host-specific adaptation governs the interaction of the marine diatom, Pseudo-nitzschia and their microbiota. ISME J. 2014;8:63-76 pubmed publisher
Schultz I, Skillman A, Sloan Evans S, Woodruff D. Domoic acid toxicokinetics in Dungeness crabs: new insights into mechanisms that regulate bioaccumulation. Aquat Toxicol. 2013;140-141:77-88 pubmed publisher
Wu D, Lu J, Zhang Y, Zheng Y, Hu B, Cheng W, et al. Ursolic acid improves domoic acid-induced cognitive deficits in mice. Toxicol Appl Pharmacol. 2013;271:127-36 pubmed publisher
McGrath T, Campbell K, Fodey T, O Kennedy R, Elliott C. An evaluation of the capability of a biolayer interferometry biosensor to detect low-molecular-weight food contaminants. Anal Bioanal Chem. 2013;405:2535-44 pubmed publisher
Giordano G, Kavanagh T, Faustman E, White C, Costa L. Low-level domoic acid protects mouse cerebellar granule neurons from acute neurotoxicity: role of glutathione. Toxicol Sci. 2013;132:399-408 pubmed publisher
Tsunekawa K, Kondo F, Okada T, Feng G, Huang L, Ishikawa N, et al. Enhanced expression of WD repeat-containing protein 35 (WDR35) stimulated by domoic acid in rat hippocampus: involvement of reactive oxygen species generation and p38 mitogen-activated protein kinase activation. BMC Neurosci. 2013;14:4 pubmed publisher
Seubert E, Gellene A, Howard M, Connell P, Ragan M, Jones B, et al. Seasonal and annual dynamics of harmful algae and algal toxins revealed through weekly monitoring at two coastal ocean sites off southern California, USA. Environ Sci Pollut Res Int. 2013;20:6878-95 pubmed publisher
McNamee S, Elliott C, Delahaut P, Campbell K. Multiplex biotoxin surface plasmon resonance method for marine biotoxins in algal and seawater samples. Environ Sci Pollut Res Int. 2013;20:6794-807 pubmed publisher
Fuentes M, Wikfors G. Control of domoic acid toxin expression in Pseudo-nitzschia multiseries by copper and silica: relevance to mussel aquaculture in New England (USA). Mar Environ Res. 2013;83:23-8 pubmed publisher
Maucher Fuquay J, Muha N, Wang Z, Ramsdell J. Elimination kinetics of domoic acid from the brain and cerebrospinal fluid of the pregnant rat. Chem Res Toxicol. 2012;25:2805-9 pubmed publisher
Baron A, Rushton S, Rens N, Morris C, Blain P, Judge S. Sex differences in effects of low level domoic acid exposure. Neurotoxicology. 2013;34:1-8 pubmed publisher
Seubert E, Trussell S, Eagleton J, Schnetzer A, Cetinić I, Lauri P, et al. Algal toxins and reverse osmosis desalination operations: laboratory bench testing and field monitoring of domoic acid, saxitoxin, brevetoxin and okadaic acid. Water Res. 2012;46:6563-73 pubmed publisher
Gulland F, Hall A, Greig D, Frame E, Colegrove K, Booth R, et al. Evaluation of circulating eosinophil count and adrenal gland function in California sea lions naturally exposed to domoic acid. J Am Vet Med Assoc. 2012;241:943-9 pubmed
Andjelkovic M, Vandevijvere S, van Klaveren J, Van Oyen H, Van Loco J. Exposure to domoic acid through shellfish consumption in Belgium. Environ Int. 2012;49:115-9 pubmed publisher
Marriott A, Ryan C, Doucette T. Neonatal domoic acid treatment produces alterations to prepulse inhibition and latent inhibition in adult rats. Pharmacol Biochem Behav. 2012;103:338-44 pubmed publisher
McGrath T, Andersson K, Campbell K, Fodey T, Elliott C. Development of a rapid low cost fluorescent biosensor for the detection of food contaminants. Biosens Bioelectron. 2013;41:96-102 pubmed publisher
Twiner M, Flewelling L, Fire S, Bowen Stevens S, Gaydos J, Johnson C, et al. Comparative analysis of three brevetoxin-associated bottlenose dolphin (Tursiops truncatus) mortality events in the Florida Panhandle region (USA). PLoS ONE. 2012;7:e42974 pubmed publisher
Gao L, Cheng J, Liu Y, Wang Q, Wang W. [Development of colloidal gold immunochromatographic strip for rapid detection of domoic acid]. Huan Jing Ke Xue. 2011;32:2492-6 pubmed
Lefebvre K, Frame E, Gulland F, Hansen J, Kendrick P, Beyer R, et al. A novel antibody-based biomarker for chronic algal toxin exposure and sub-acute neurotoxicity. PLoS ONE. 2012;7:e36213 pubmed publisher
Lelong A, Jolley D, Soudant P, Hégaret H. Impact of copper exposure on Pseudo-nitzschia spp. physiology and domoic acid production. Aquat Toxicol. 2012;118-119:37-47 pubmed publisher
Wang Q, Cheng J, Gao L, Dong Y, Xi L. [Development of direct competitive enzyme-linked immunosorbent assay for the determination of domoic acid]. Huan Jing Ke Xue. 2012;33:647-51 pubmed
Wu D, Lu J, Zheng Y, Zhang Y, Hu B, Cheng W, et al. Small interfering RNA-mediated knockdown of protein kinase C zeta attenuates domoic acid-induced cognitive deficits in mice. Toxicol Sci. 2012;128:209-22 pubmed publisher
Zhang X, Zhang Z. Quantification of domoic acid in shellfish samples by capillary electrophoresis-based enzyme immunoassay with electrochemical detection. Toxicon. 2012;59:626-32 pubmed publisher
Samengo I, Curro D, Navarra P, Barrese V, Taglialatela M, Martire M. Molecular and pharmacological evidence for a facilitatory functional role of pre-synaptic GLUK2/3 kainate receptors on GABA release in rat trigeminal caudal nucleus. Eur J Pain. 2012;16:1148-57 pubmed publisher
Gill D, Perry M, McGuire E, Pérez Gómez A, Tasker R. Low-dose neonatal domoic acid causes persistent changes in behavioural and molecular indicators of stress response in rats. Behav Brain Res. 2012;230:409-17 pubmed publisher
Perez Gomez A, Tasker R. Enhanced neurogenesis in organotypic cultures of rat hippocampus after transient subfield-selective excitotoxic insult induced by domoic acid. Neuroscience. 2012;208:97-108 pubmed publisher
Tatters A, Fu F, Hutchins D. High CO2 and silicate limitation synergistically increase the toxicity of Pseudo-nitzschia fraudulenta. PLoS ONE. 2012;7:e32116 pubmed publisher
Maucher Fuquay J, Muha N, Wang Z, Ramsdell J. Toxicokinetics of domoic acid in the fetal rat. Toxicology. 2012;294:36-41 pubmed publisher
Wang Z, Maucher Fuquay J, Fire S, Mikulski C, Haynes B, Doucette G, et al. Optimization of solid-phase extraction and liquid chromatography-tandem mass spectrometry for the determination of domoic acid in seawater, phytoplankton, and mammalian fluids and tissues. Anal Chim Acta. 2012;715:71-9 pubmed publisher
Lu J, Wu D, Zheng Y, Hu B, Cheng W, Zhang Z. Purple sweet potato color attenuates domoic acid-induced cognitive deficits by promoting estrogen receptor-α-mediated mitochondrial biogenesis signaling in mice. Free Radic Biol Med. 2012;52:646-659 pubmed publisher
He Y, Fekete A, Chen G, Harir M, Zhang L, Tong P, et al. Analytical approaches for an important shellfish poisoning agent: domoic Acid. J Agric Food Chem. 2010;58:11525-33 pubmed publisher
Costa L, Giordano G, Faustman E. Domoic acid as a developmental neurotoxin. Neurotoxicology. 2010;31:409-23 pubmed publisher
Kumar K, Kumar S, Nair G. Risk assessment of the amnesic shellfish poison, domoic acid, on animals and humans. J Environ Biol. 2009;30:319-25 pubmed
Grant K, Burbacher T, Faustman E, Gratttan L. Domoic acid: neurobehavioral consequences of exposure to a prevalent marine biotoxin. Neurotoxicol Teratol. 2010;32:132-41 pubmed publisher
Tanemura K, Igarashi K, Matsugami T, Aisaki K, Kitajima S, Kanno J. Intrauterine environment-genome interaction and children's development (2): Brain structure impairment and behavioral disturbance induced in male mice offspring by a single intraperitoneal administration of domoic acid (DA) to their dams. J Toxicol Sci. 2009;34 Suppl 2:SP279-86 pubmed
Lefebvre K, Robertson A. Domoic acid and human exposure risks: a review. Toxicon. 2010;56:218-30 pubmed publisher
Ramsdell J, Zabka T. In utero domoic acid toxicity: a fetal basis to adult disease in the California sea lion (Zalophus californianus). Mar Drugs. 2008;6:262-90 pubmed publisher
Pulido O. Domoic acid toxicologic pathology: a review. Mar Drugs. 2008;6:180-219 pubmed publisher
Wu D, Li F. [Domoic acid and human health]. Wei Sheng Yan Jiu. 2005;34:378-81 pubmed
Chandrasekaran A, Ponnambalam G, Kaur C. Domoic acid-induced neurotoxicity in the hippocampus of adult rats. Neurotox Res. 2004;6:105-17 pubmed
Chen X, Wang C. [Domoic acid and glutamate receptors]. Wei Sheng Yan Jiu. 2000;29:255-6, back cover pubmed
Hampson D, Manalo J. The activation of glutamate receptors by kainic acid and domoic acid. Nat Toxins. 1998;6:153-8 pubmed
Vecsei L, Dibó G, Kiss C. Neurotoxins and neurodegenerative disorders. Neurotoxicology. 1998;19:511-4 pubmed
Iverson F, Truelove J. Toxicology and seafood toxins: domoic acid. Nat Toxins. 1994;2:334-9 pubmed
Hampson D, Wenthold R. A kainic acid receptor from frog brain purified using domoic acid affinity chromatography. J Biol Chem. 1988;263:2500-5 pubmed
Tryphonas L, Iverson F. Neuropathology of excitatory neurotoxins: the domoic acid model. Toxicol Pathol. 1990;18:165-9 pubmed
Hampson D, Huang X, Wells J, Walter J, Wright J. Interaction of domoic acid and several derivatives with kainic acid and AMPA binding sites in rat brain. Eur J Pharmacol. 1992;218:1-8 pubmed
product information
Catalog Number :
D6152
Product Name :
Domoic acid
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥90% (HPLC)
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA