This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
DT Diaphorase (NQO1) human
catalog :
D1315
citations: 12
Reference |
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Oh E, Park H. Implications of NQO1 in cancer therapy. BMB Rep. 2015;48:609-17 pubmed
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Flader C, Liu J, Borch R. Development of novel quinone phosphorodiamidate prodrugs targeted to DT-diaphorase. J Med Chem. 2000;43:3157-67 pubmed
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Skelly J, Sanderson M, Suter D, Baumann U, Read M, Gregory D, et al. Crystal structure of human DT-diaphorase: a model for interaction with the cytotoxic prodrug 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954). J Med Chem. 1999;42:4325-30 pubmed
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Chen S, Wu K, Zhang D, Sherman M, Knox R, Yang C. Molecular characterization of binding of substrates and inhibitors to DT-diaphorase: combined approach involving site-directed mutagenesis, inhibitor-binding analysis, and computer modeling. Mol Pharmacol. 1999;56:272-8 pubmed
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Chen S, Knox R, Wu K, Deng P, Zhou D, Bianchet M, et al. Molecular basis of the catalytic differences among DT-diaphorase of human, rat, and mouse. J Biol Chem. 1997;272:1437-9 pubmed
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product information
Catalog Number :
D1315
Product Name :
DT Diaphorase (NQO1) human
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
lyophilized powder, recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
company information

MilliporeSigma
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