product summary
company name :
MilliporeSigma
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-Desmin antibody produced in mouse
catalog :
D1033
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
DE-U-10
reactivity :
human, mouse, rat, chicken, bovine, domestic sheep
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, western blot knockout validation
more info or order :
citations: 107
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1:1000; fig 4
Winter L, Wittig I, Peeva V, Eggers B, Heidler J, Chevessier F, et al. Mutant desmin substantially perturbs mitochondrial morphology, function and maintenance in skeletal muscle tissue. Acta Neuropathol. 2016;132:453-73 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1d
Catalano A, Adlesic M, Kaltenbacher T, Klar R, Albers J, Seidel P, et al. Sensitivity and Resistance of Oncogenic RAS-Driven Tumors to Dual MEK and ERK Inhibition. Cancers (Basel). 2021;13: pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:80; loading ...; fig 2a
Nofi C, Bogatyryov Y, Dedkov E. Preservation of Functional Microvascular Bed Is Vital for Long-Term Survival of Cardiac Myocytes Within Large Transmural Post-Myocardial Infarction Scar. J Histochem Cytochem. 2017;:22155417741640 pubmed publisher
  • immunocytochemistry; human; fig 6
Park S, Choi Y, Jung N, Kim J, Oh S, Yu Y, et al. Autophagy induction in the skeletal myogenic differentiation of human tonsil-derived mesenchymal stem cells. Int J Mol Med. 2017;39:831-840 pubmed publisher
  • western blot; rat; 1:7000; loading ...; fig 5b
Kovacs A, Kalász J, Pasztor E, Toth A, Papp Z, Dhalla N, et al. Myosin heavy chain and cardiac troponin T damage is associated with impaired myofibrillar ATPase activity contributing to sarcomeric dysfunction in Ca2+-paradox rat hearts. Mol Cell Biochem. 2017;430:57-68 pubmed publisher
  • immunocytochemistry; human; 1:1000; fig 2
Kim E, Page P, Dellefave Castillo L, McNally E, Wyatt E. Direct reprogramming of urine-derived cells with inducible MyoD for modeling human muscle disease. Skelet Muscle. 2016;6:32 pubmed publisher
  • immunocytochemistry; human; fig 2
El Kehdy H, Pourcher G, Zhang W, Hamidouche Z, Goulinet Mainot S, Sokal E, et al. Hepatocytic Differentiation Potential of Human Fetal Liver Mesenchymal Stem Cells: In Vitro and In Vivo Evaluation. Stem Cells Int. 2016;2016:6323486 pubmed publisher
  • immunocytochemistry; human; fig 4
  • western blot; human; fig 3
Park S, Choi Y, Jung N, Yu Y, Ryu K, Kim H, et al. Myogenic differentiation potential of human tonsil-derived mesenchymal stem cells and their potential for use to promote skeletal muscle regeneration. Int J Mol Med. 2016;37:1209-20 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 3
Morena D, Maestro N, Bersani F, Forni P, Lingua M, Foglizzo V, et al. Hepatocyte Growth Factor-mediated satellite cells niche perturbation promotes development of distinct sarcoma subtypes. elife. 2016;5: pubmed publisher
  • immunocytochemistry; mouse; 1:50; fig s2a-g
Fuchs C, Gawlas S, Heher P, Nikouli S, Paar H, Ivankovic M, et al. Desmin enters the nucleus of cardiac stem cells and modulates Nkx2.5 expression by participating in transcription factor complexes that interact with the nkx2.5 gene. Biol Open. 2016;5:140-53 pubmed publisher
  • immunocytochemistry; mouse; 1:500; fig 7a
Tóth A, Fodor J, Vincze J, Oláh T, Juhász T, Zákány R, et al. The Effect of SERCA1b Silencing on the Differentiation and Calcium Homeostasis of C2C12 Skeletal Muscle Cells. PLoS ONE. 2015;10:e0123583 pubmed publisher
  • immunohistochemistry - paraffin section; human
Folmsbee S, Morales Nebreda L, van Hengel J, Tyberghein K, van Roy F, Budinger G, et al. The cardiac protein αT-catenin contributes to chemical-induced asthma. Am J Physiol Lung Cell Mol Physiol. 2015;308:L253-8 pubmed publisher
  • immunohistochemistry; rat; 1:80
Ozdemir C, Akpulat U, Sharafi P, Yıldız Y, Onbaşılar I, Kocaefe C. Periostin is temporally expressed as an extracellular matrix component in skeletal muscle regeneration and differentiation. Gene. 2014;553:130-9 pubmed publisher
  • western blot; bovine; 1:5000
Lomiwes D, Hurst S, Dobbie P, Frost D, Hurst R, Young O, et al. The protection of bovine skeletal myofibrils from proteolytic damage post mortem by small heat shock proteins. Meat Sci. 2014;97:548-57 pubmed publisher
  • immunohistochemistry; domestic sheep; 0.3 ug/ml
Tripathi A, Patel A, Shah R, Patel A, Shah T, Bhatt V, et al. Transcriptomic dissection of myogenic differentiation signature in caprine by RNA-Seq. Mech Dev. 2014;132:79-92 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 3
Okumura N, Akutsu H, Sugawara T, Miura T, Takezawa Y, Hosoda A, et al. ?-catenin functions pleiotropically in differentiation and tumorigenesis in mouse embryo-derived stem cells. PLoS ONE. 2013;8:e63265 pubmed publisher
Mehdipour M, Etienne J, Chen C, Gathwala R, Rehman M, Kato C, et al. Rejuvenation of brain, liver and muscle by simultaneous pharmacological modulation of two signaling determinants, that change in opposite directions with age. Aging (Albany NY). 2019;11:5628-5645 pubmed publisher
Takizawa H, Hara Y, Mizobe Y, Ohno T, Suzuki S, Inoue K, et al. Modelling Duchenne muscular dystrophy in MYOD1-converted urine-derived cells treated with 3-deazaneplanocin A hydrochloride. Sci Rep. 2019;9:3807 pubmed publisher
Ma X, Mani K, Liu H, Kovacs A, Murphy J, Foroughi L, et al. Transcription Factor EB Activation Rescues Advanced αB-Crystallin Mutation-Induced Cardiomyopathy by Normalizing Desmin Localization. J Am Heart Assoc. 2019;8:e010866 pubmed publisher
Karbassi E, Rosa Garrido M, Chapski D, Wu Y, Ren S, Wang Y, et al. Direct visualization of cardiac transcription factories reveals regulatory principles of nuclear architecture during pathological remodeling. J Mol Cell Cardiol. 2019;128:198-211 pubmed publisher
Schips T, Vanhoutte D, Vo A, Correll R, Brody M, Khalil H, et al. Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability. Nat Commun. 2019;10:76 pubmed publisher
Bell E, Shine R, Dwyer P, Olson L, Truong J, Fredenburg R, et al. PPARδ modulation rescues mitochondrial fatty acid oxidation defects in the mdx model of muscular dystrophy. Mitochondrion. 2019;46:51-58 pubmed publisher
Hamoud N, Tran V, Aimi T, Kakegawa W, Lahaie S, Thibault M, et al. Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion. Nat Commun. 2018;9:4470 pubmed publisher
Castillero E, Ali Z, Akashi H, Giangreco N, Wang C, Stöhr E, et al. Structural and functional cardiac profile after prolonged duration of mechanical unloading: potential implications for myocardial recovery. Am J Physiol Heart Circ Physiol. 2018;315:H1463-H1476 pubmed publisher
Gholobova D, Gerard M, Decroix L, Desender L, Callewaert N, Annaert P, et al. Human tissue-engineered skeletal muscle: a novel 3D in vitro model for drug disposition and toxicity after intramuscular injection. Sci Rep. 2018;8:12206 pubmed publisher
Ding S, Swennen G, Messmer T, Gagliardi M, Molin D, Li C, et al. Maintaining bovine satellite cells stemness through p38 pathway. Sci Rep. 2018;8:10808 pubmed publisher
Thomas M, Pierson M, Uprety T, Zhu L, Ran Z, Sreenivasan C, et al. Comparison of Porcine Airway and Intestinal Epithelial Cell Lines for the Susceptibility and Expression of Pattern Recognition Receptors upon Influenza Virus Infection. Viruses. 2018;10: pubmed publisher
Brandt L, Albers J, Hejhal T, Pfundstein S, Gonçalves A, Catalano A, et al. Mouse genetic background influences whether HrasG12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma. Oncotarget. 2018;9:19753-19766 pubmed publisher
Bi P, McAnally J, Shelton J, Sanchez Ortiz E, Bassel Duby R, Olson E. Fusogenic micropeptide Myomixer is essential for satellite cell fusion and muscle regeneration. Proc Natl Acad Sci U S A. 2018;115:3864-3869 pubmed publisher
Molinari F, Pin F, Gorini S, Chiandotto S, Pontecorvo L, Penna F, et al. The mitochondrial metabolic reprogramming agent trimetazidine as an 'exercise mimetic' in cachectic C26-bearing mice. J Cachexia Sarcopenia Muscle. 2017;8:954-973 pubmed publisher
Brandt L, Albers J, Hejhal T, Catalano A, Wild P, Frew I. Oncogenic HrasG12V expression plus knockdown of Cdkn2a using ecotropic lentiviral vectors induces high-grade endometrial stromal sarcoma. PLoS ONE. 2017;12:e0186102 pubmed publisher
Bouvet M, Dubois Deruy E, Alayi T, Mulder P, El Amranii M, Beseme O, et al. Increased level of phosphorylated desmin and its degradation products in heart failure. Biochem Biophys Rep. 2016;6:54-62 pubmed publisher
Zhang S, Yeap X, DeBerge M, Naresh N, Wang K, Jiang Z, et al. Acute CD47 Blockade During Ischemic Myocardial Reperfusion Enhances Phagocytosis-Associated Cardiac Repair. JACC Basic Transl Sci. 2017;2:386-397 pubmed publisher
Jordan S, Kriebs A, Vaughan M, Duglan D, Fan W, Henriksson E, et al. CRY1/2 Selectively Repress PPARδ and Limit Exercise Capacity. Cell Metab. 2017;26:243-255.e6 pubmed publisher
Li Y, Wen Y, Green M, Cabral E, Wani P, Zhang F, et al. Cell sex affects extracellular matrix protein expression and proliferation of smooth muscle progenitor cells derived from human pluripotent stem cells. Stem Cell Res Ther. 2017;8:156 pubmed publisher
Nghiem P, Bello L, Balog Alvarez C, López S, Bettis A, Barnett H, et al. Whole genome sequencing reveals a 7 base-pair deletion in DMD exon 42 in a dog with muscular dystrophy. Mamm Genome. 2017;28:106-113 pubmed publisher
Kim J, de Sampaio P, Lundy D, Peng Q, Evans K, Sugimoto H, et al. Heterogeneous perivascular cell coverage affects breast cancer metastasis and response to chemotherapy. JCI Insight. 2016;1:e90733 pubmed publisher
Hernandez D, Bennett C, Dunina Barkovskaya L, Wedig T, Capetanaki Y, Herrmann H, et al. Nebulette is a powerful cytolinker organizing desmin and actin in mouse hearts. Mol Biol Cell. 2016;27:3869-3882 pubmed
Mizbani A, Luca E, Rushing E, Krutzfeldt J. MicroRNA deep sequencing in two adult stem cell populations identifies miR-501 as a novel regulator of myosin heavy chain during muscle regeneration. Development. 2016;143:4137-4148 pubmed
Ferraro E, Pin F, Gorini S, Pontecorvo L, Ferri A, Mollace V, et al. Improvement of skeletal muscle performance in ageing by the metabolic modulator Trimetazidine. J Cachexia Sarcopenia Muscle. 2016;7:449-57 pubmed publisher
Sente T, Van Berendoncks A, Jonckheere A, Rodenburg R, Lauwers P, Van Hoof V, et al. Primary skeletal muscle myoblasts from chronic heart failure patients exhibit loss of anti-inflammatory and proliferative activity. BMC Cardiovasc Disord. 2016;16:107 pubmed publisher
Lenti E, Farinello D, Yokoyama K, Penkov D, Castagnaro L, Lavorgna G, et al. Transcription factor TLX1 controls retinoic acid signaling to ensure spleen development. J Clin Invest. 2016;126:2452-64 pubmed publisher
Park S, Yun Y, Lim J, Kim M, Kim S, Kim J, et al. Stabilin-2 modulates the efficiency of myoblast fusion during myogenic differentiation and muscle regeneration. Nat Commun. 2016;7:10871 pubmed publisher
Folmsbee S, Budinger G, Bryce P, Gottardi C. The cardiomyocyte protein ?T-catenin contributes to asthma through regulating pulmonary vein inflammation. J Allergy Clin Immunol. 2016;138:123-129.e2 pubmed publisher
Feng H, Chen X, Malek M, Jin J. Slow recovery of the impaired fatigue resistance in postunloading mouse soleus muscle corresponding to decreased mitochondrial function and a compensatory increase in type I slow fibers. Am J Physiol Cell Physiol. 2016;310:C27-40 pubmed publisher
Zhang S, Yeap X, Grigoryeva L, Dehn S, DeBerge M, Tye M, et al. Cardiomyocytes induce macrophage receptor shedding to suppress phagocytosis. J Mol Cell Cardiol. 2015;87:171-9 pubmed publisher
Gholobova D, Decroix L, Van Muylder V, Desender L, Gerard M, Carpentier G, et al. Endothelial Network Formation Within Human Tissue-Engineered Skeletal Muscle. Tissue Eng Part A. 2015;21:2548-58 pubmed publisher
Tan R, Zhou D, Xiao L, Zhou L, Li Y, Bastacky S, et al. Extracellular Superoxide Dismutase Protects against Proteinuric Kidney Disease. J Am Soc Nephrol. 2015;26:2447-59 pubmed publisher
Clemen C, Stöckigt F, Strucksberg K, Chevessier F, Winter L, Schütz J, et al. The toxic effect of R350P mutant desmin in striated muscle of man and mouse. Acta Neuropathol. 2015;129:297-315 pubmed publisher
WÃ¥hlin Larsson B, Carnac G, Kadi F. The influence of systemic inflammation on skeletal muscle in physically active elderly women. Age (Dordr). 2014;36:9718 pubmed publisher
Monti M, Solito R, Puccetti L, Pasotti L, Roggeri R, Monzani E, et al. Protective effects of novel metal-nonoates on the cellular components of the vascular system. J Pharmacol Exp Ther. 2014;351:500-9 pubmed publisher
Li P, Wang T, Mao Y, Zhang Y, Niu L, Liang R, et al. Effect of ultimate pH on postmortem myofibrillar protein degradation and meat quality characteristics of Chinese Yellow crossbreed cattle. ScientificWorldJournal. 2014;2014:174253 pubmed publisher
Roth L, Gaba A, Cheng L. On the pathogenesis of sclerosing stromal tumor of the ovary: a neoplasm in transition. Int J Gynecol Pathol. 2014;33:449-62 pubmed publisher
Park D, Lee J, Park I, Choi D, Lee S, Song S, et al. Lymphatic regulator PROX1 determines Schlemm's canal integrity and identity. J Clin Invest. 2014;124:3960-74 pubmed publisher
Zhou L, Li Y, Hao S, Zhou D, Tan R, Nie J, et al. Multiple genes of the renin-angiotensin system are novel targets of Wnt/?-catenin signaling. J Am Soc Nephrol. 2015;26:107-20 pubmed publisher
Bañón Maneus E, Rovira J, Ramírez Bajo M, Moya Rull D, Hierro Garcia N, Takenaka S, et al. Wnt pathway activation in long term remnant rat model. Biomed Res Int. 2014;2014:324713 pubmed publisher
Kayman Kurekci G, Talim B, Korkusuz P, Sayar N, Sarioglu T, Oncel I, et al. Mutation in TOR1AIP1 encoding LAP1B in a form of muscular dystrophy: a novel gene related to nuclear envelopathies. Neuromuscul Disord. 2014;24:624-33 pubmed publisher
Witt W, Buttner P, Jannasch A, Matschke K, Waldow T. Reversal of myofibroblastic activation by polyunsaturated fatty acids in valvular interstitial cells from aortic valves. Role of RhoA/G-actin/MRTF signalling. J Mol Cell Cardiol. 2014;74:127-38 pubmed publisher
Zhou D, Li Y, Zhou L, Tan R, Xiao L, Liang M, et al. Sonic hedgehog is a novel tubule-derived growth factor for interstitial fibroblasts after kidney injury. J Am Soc Nephrol. 2014;25:2187-200 pubmed publisher
Binh N, Aoki H, Takamatsu M, Hatano Y, Hirata A, Tomita H, et al. Time-sensitive effects of hypoxia on differentiation of neural stem cells derived from mouse embryonic stem cells in vitro. Neurol Res. 2014;36:804-13 pubmed publisher
Cheng X, Zhang X, Cheng W, Chen J, Ma C, Yang B, et al. Tumor-specific delivery of histidine-rich glycoprotein suppresses tumor growth and metastasis by anti-angiogenesis and vessel normalization. Curr Gene Ther. 2014;14:75-85 pubmed
Fruhwürth S, Pavelka M, Bittman R, Kovacs W, Walter K, Röhrl C, et al. High-density lipoprotein endocytosis in endothelial cells. World J Biol Chem. 2013;4:131-40 pubmed publisher
Yoon S, Stadler G, Beermann M, Schmidt E, Windelborn J, Schneiderat P, et al. Immortalized myogenic cells from congenital muscular dystrophy type1A patients recapitulate aberrant caspase activation in pathogenesis: a new tool for MDC1A research. Skelet Muscle. 2013;3:28 pubmed publisher
Brodehl A, Dieding M, Klauke B, Dec E, Madaan S, Huang T, et al. The novel desmin mutant p.A120D impairs filament formation, prevents intercalated disk localization, and causes sudden cardiac death. Circ Cardiovasc Genet. 2013;6:615-23 pubmed publisher
Arechederra M, Carmona R, Gonzalez Nuñez M, Gutierrez Uzquiza A, Bragado P, Cruz Gonzalez I, et al. Met signaling in cardiomyocytes is required for normal cardiac function in adult mice. Biochim Biophys Acta. 2013;1832:2204-15 pubmed publisher
Bogatyryov Y, Tomanek R, Dedkov E. Structural composition of myocardial infarction scar in middle-aged male and female rats: does sex matter?. J Histochem Cytochem. 2013;61:833-48 pubmed publisher
Yousef H, Conboy M, Li J, Zeiderman M, Vazin T, Schlesinger C, et al. hESC-secreted proteins can be enriched for multiple regenerative therapies by heparin-binding. Aging (Albany NY). 2013;5:357-72 pubmed
Cetin N, Balci Hayta B, Gundesli H, Korkusuz P, Purali N, Talim B, et al. A novel desmin mutation leading to autosomal recessive limb-girdle muscular dystrophy: distinct histopathological outcomes compared with desminopathies. J Med Genet. 2013;50:437-43 pubmed publisher
Baker L, Gillis D, Sharma S, Ambrus A, Herrmann H, Conover G. Nebulin binding impedes mutant desmin filament assembly. Mol Biol Cell. 2013;24:1918-32 pubmed publisher
Hassiotou F, Hepworth A, Beltran A, Mathews M, Stuebe A, Hartmann P, et al. Expression of the Pluripotency Transcription Factor OCT4 in the Normal and Aberrant Mammary Gland. Front Oncol. 2013;3:79 pubmed publisher
Bichsel C, Neeld D, Hamazaki T, Chang L, Yang L, Terada N, et al. Direct reprogramming of fibroblasts to myocytes via bacterial injection of MyoD protein. Cell Reprogram. 2013;15:117-25 pubmed publisher
Han Y, Brozovich F. Altered reactivity of tertiary mesenteric arteries following acute myocardial ischemia. J Vasc Res. 2013;50:100-8 pubmed publisher
Lorenzon A, Beffagna G, Bauce B, De Bortoli M, Li Mura I, Calore M, et al. Desmin mutations and arrhythmogenic right ventricular cardiomyopathy. Am J Cardiol. 2013;111:400-5 pubmed publisher
Sun Z, Huber V, McCormick K, Kaushik R, Boon A, Zhu L, et al. Characterization of a porcine intestinal epithelial cell line for influenza virus production. J Gen Virol. 2012;93:2008-16 pubmed publisher
Liu S, Hartleben B, Kretz O, Wiech T, Igarashi P, Mizushima N, et al. Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury. Autophagy. 2012;8:826-37 pubmed publisher
Corona B, Machingal M, Criswell T, Vadhavkar M, Dannahower A, Bergman C, et al. Further development of a tissue engineered muscle repair construct in vitro for enhanced functional recovery following implantation in vivo in a murine model of volumetric muscle loss injury. Tissue Eng Part A. 2012;18:1213-28 pubmed publisher
Ding H, Zhou D, Hao S, Zhou L, He W, Nie J, et al. Sonic hedgehog signaling mediates epithelial-mesenchymal communication and promotes renal fibrosis. J Am Soc Nephrol. 2012;23:801-13 pubmed publisher
Kim Y, Stuart A, Nygaard G, Rosenvold K. High pre rigor temperature limits the ageing potential of beef that is not completely overcome by electrical stimulation and muscle restraining. Meat Sci. 2012;91:62-8 pubmed publisher
Sabatelli P, Palma E, Angelin A, Squarzoni S, Urciuolo A, Pellegrini C, et al. Critical evaluation of the use of cell cultures for inclusion in clinical trials of patients affected by collagen VI myopathies. J Cell Physiol. 2012;227:2927-35 pubmed publisher
Pol C, Muller A, Zuidwijk M, van Deel E, Kaptein E, Saba A, et al. Left-ventricular remodeling after myocardial infarction is associated with a cardiomyocyte-specific hypothyroid condition. Endocrinology. 2011;152:669-79 pubmed publisher
Kaftanovskaya E, Feng S, Huang Z, Tan Y, Barbara A, Kaur S, et al. Suppression of insulin-like3 receptor reveals the role of ?-catenin and Notch signaling in gubernaculum development. Mol Endocrinol. 2011;25:170-83 pubmed publisher
Mohrhauser D, Underwood K, Weaver A. In vitro degradation of bovine myofibrils is caused by μ-calpain, not caspase-3. J Anim Sci. 2011;89:798-808 pubmed publisher
Obokata H, Kojima K, Westerman K, Yamato M, Okano T, Tsuneda S, et al. The potential of stem cells in adult tissues representative of the three germ layers. Tissue Eng Part A. 2011;17:607-15 pubmed publisher
Rosenvold K, Borup U, Therkildsen M. Stepwise chilling: tender pork without compromising water-holding capacity. J Anim Sci. 2010;88:1830-41 pubmed publisher
Carlson M, Conboy M, Hsu M, Barchas L, Jeong J, Agrawal A, et al. Relative roles of TGF-beta1 and Wnt in the systemic regulation and aging of satellite cell responses. Aging Cell. 2009;8:676-89 pubmed publisher
Froeling F, Mirza T, Feakins R, Seedhar A, Elia G, Hart I, et al. Organotypic culture model of pancreatic cancer demonstrates that stromal cells modulate E-cadherin, beta-catenin, and Ezrin expression in tumor cells. Am J Pathol. 2009;175:636-48 pubmed publisher
Raymond A, Shur B. A novel role for SED1 (MFG-E8) in maintaining the integrity of the epididymal epithelium. J Cell Sci. 2009;122:849-58 pubmed publisher
Sackett S, Li Z, Hurtt R, Gao Y, Wells R, Brondell K, et al. Foxl1 is a marker of bipotential hepatic progenitor cells in mice. Hepatology. 2009;49:920-9 pubmed publisher
Veselska R, Hermanova M, Loja T, Chlapek P, Zambo I, Vesely K, et al. Nestin expression in osteosarcomas and derivation of nestin/CD133 positive osteosarcoma cell lines. BMC Cancer. 2008;8:300 pubmed publisher
Svärd J, Rozell B, Toftgard R, Teglund S. Tumor suppressor gene co-operativity in compound Patched1 and suppressor of fused heterozygous mutant mice. Mol Carcinog. 2009;48:408-19 pubmed publisher
Mavroidis M, Panagopoulou P, Kostavasili I, Weisleder N, Capetanaki Y. A missense mutation in desmin tail domain linked to human dilated cardiomyopathy promotes cleavage of the head domain and abolishes its Z-disc localization. FASEB J. 2008;22:3318-27 pubmed publisher
Wong C, Tellam R. MicroRNA-26a targets the histone methyltransferase Enhancer of Zeste homolog 2 during myogenesis. J Biol Chem. 2008;283:9836-43 pubmed publisher
Blunt B, Creek A, Henderson D, Hofmann P. H2O2 activation of HSP25/27 protects desmin from calpain proteolysis in rat ventricular myocytes. Am J Physiol Heart Circ Physiol. 2007;293:H1518-25 pubmed
Stockholm D, Benchaouir R, Picot J, Rameau P, Neildez T, Landini G, et al. The origin of phenotypic heterogeneity in a clonal cell population in vitro. PLoS ONE. 2007;2:e394 pubmed
Carlson M, Conboy I. Loss of stem cell regenerative capacity within aged niches. Aging Cell. 2007;6:371-82 pubmed
Taylor M, Slavov D, Ku L, Di Lenarda A, Sinagra G, Carniel E, et al. Prevalence of desmin mutations in dilated cardiomyopathy. Circulation. 2007;115:1244-51 pubmed
Choi Y, Stamm C, Hammer P, Kwaku K, Marler J, Friehs I, et al. Cardiac conduction through engineered tissue. Am J Pathol. 2006;169:72-85 pubmed
Tolmachov O, Ma Y, Themis M, Patel P, Spohr H, MacLeod K, et al. Overexpression of connexin 43 using a retroviral vector improves electrical coupling of skeletal myoblasts with cardiac myocytes in vitro. BMC Cardiovasc Disord. 2006;6:25 pubmed
Dohmann H, Perin E, Takiya C, Silva G, Silva S, Sousa A, et al. Transendocardial autologous bone marrow mononuclear cell injection in ischemic heart failure: postmortem anatomicopathologic and immunohistochemical findings. Circulation. 2005;112:521-6 pubmed
Qu Petersen Z, Deasy B, Jankowski R, Ikezawa M, Cummins J, Pruchnic R, et al. Identification of a novel population of muscle stem cells in mice: potential for muscle regeneration. J Cell Biol. 2002;157:851-64 pubmed
Wede O, Löfgren M, Li Z, Paulin D, Arner A. Mechanical function of intermediate filaments in arteries of different size examined using desmin deficient mice. J Physiol. 2002;540:941-9 pubmed
McKaig B, Hughes K, Tighe P, Mahida Y. Differential expression of TGF-beta isoforms by normal and inflammatory bowel disease intestinal myofibroblasts. Am J Physiol Cell Physiol. 2002;282:C172-82 pubmed
Park K, Dalakas M, Goebel H, Ferrans V, Semino Mora C, Litvak S, et al. Desmin splice variants causing cardiac and skeletal myopathy. J Med Genet. 2000;37:851-7 pubmed
Dalakas M, Park K, Semino Mora C, Lee H, Sivakumar K, Goldfarb L. Desmin myopathy, a skeletal myopathy with cardiomyopathy caused by mutations in the desmin gene. N Engl J Med. 2000;342:770-80 pubmed
Jobson T, Billington C, Hall I. Regulation of proliferation of human colonic subepithelial myofibroblasts by mediators important in intestinal inflammation. J Clin Invest. 1998;101:2650-7 pubmed
Claycomb W, Lanson N, Stallworth B, Egeland D, Delcarpio J, Bahinski A, et al. HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte. Proc Natl Acad Sci U S A. 1998;95:2979-84 pubmed
Debus E, Weber K, Osborn M. Monoclonal antibodies to desmin, the muscle-specific intermediate filament protein. EMBO J. 1983;2:2305-12 pubmed
product information
Product No. :
D1033
Product Name :
Monoclonal Anti-Desmin antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
DE-U-10
Applications/Description :
Suitable for indirect immunofluorescence: 1:40 using formalin-fixed, paraffin-embedded sections of human tissue; western blot: 1:200 using chicken gizzard extract/whole extract of mouse myoblast C2C12 cells; microarray
Species Reactivity :
mouse, goat, rat, bovine, chicken, viper, rabbit, hamster, lizard, feline, sheep, human
Isotype :
IgG1
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA