Arias Fuenzalida J, Jarazo J, Walter J, Gomez Giro G, Forster J, Krueger R, et al. Automated high-throughput high-content autophagy and mitophagy analysis platform. Sci Rep. 2019;9:9455 pubmed publisher

Weckbach L, Grabmaier U, Uhl A, Gess S, Boehm F, Zehrer A, et al. Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis. J Exp Med. 2019;216:350-368 pubmed publisher

Mir R, Tonelli F, Lis P, MacArtney T, Polinski N, Martinez T, et al. The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human. Biochem J. 2018;475:1861-1883 pubmed publisher

Pitts M, Combs T, D Orazio S. Neutrophils from Both Susceptible and Resistant Mice Efficiently Kill Opsonized Listeria monocytogenes. Infect Immun. 2018;86: pubmed publisher

Fan Y, Howden A, Sarhan A, Lis P, Ito G, Martinez T, et al. Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils. Biochem J. 2018;475:23-44 pubmed publisher

Hooshmand M, Nguyen H, Piltti K, Benavente F, Hong S, Flanagan L, et al. Neutrophils Induce Astroglial Differentiation and Migration of Human Neural Stem Cells via C1q and C3a Synthesis. J Immunol. 2017;199:1069-1085 pubmed publisher

Sylvain Prévost S, Ear T, Simard F, Fortin C, Dubois C, Flamand N, et al. Activation of TAK1 by Chemotactic and Growth Factors, and Its Impact on Human Neutrophil Signaling and Functional Responses. J Immunol. 2015;195:5393-403 pubmed publisher

Ferchmin P, Pérez D, Cuadrado B, Carrasco M, Martins A, Eterović V. Neuroprotection Against Diisopropylfluorophosphate in Acute Hippocampal Slices. Neurochem Res. 2015;40:2143-51 pubmed publisher

Nobles C, Clark J, Green S, Maresso A. A dual component heme biosensor that integrates heme transport and synthesis in bacteria. J Microbiol Methods. 2015;118:7-17 pubmed publisher

Mazzi P, Caveggion E, Lapinet Vera J, Lowell C, Berton G. The Src-Family Kinases Hck and Fgr Regulate Early Lipopolysaccharide-Induced Myeloid Cell Recruitment into the Lung and Their Ability To Secrete Chemokines. J Immunol. 2015;195:2383-95 pubmed publisher

Crisponi G, Nurchi V, Crespo Alonso M, Sanna G, Zoroddu M, Alberti G, et al. A Speciation Study on the Perturbing Effects of Iron Chelators on the Homeostasis of Essential Metal Ions. PLoS ONE. 2015;10:e0133050 pubmed publisher

Chillappagari S, Preuss J, Licht S, Müller C, Mahavadi P, Sarode G, et al. Altered protease and antiprotease balance during a COPD exacerbation contributes to mucus obstruction. Respir Res. 2015;16:85 pubmed publisher

Zühlsdorf M, Werten S, Klupp B, Palm G, Mettenleiter T, Hinrichs W. Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin pUL26N, a Herpesvirus Serine Protease. PLoS Pathog. 2015;11:e1005045 pubmed publisher

Yin L, Meng X, Zhou X, Zhang T, Sun H, Yang Z, et al. Simultaneous determination of carboprost methylate and its active metabolite carboprost in dog plasma by liquid chromatography-tandem mass spectrometry with positive/negative ion-switching electrospray ionization and its application to a pharmacokine. J Chromatogr B Analyt Technol Biomed Life Sci. 2015;998-999:8-14 pubmed publisher

Ruiz C, Rossi S, Rotundo R. Rescue and Stabilization of Acetylcholinesterase in Skeletal Muscle by N-terminal Peptides Derived from the Noncatalytic Subunits. J Biol Chem. 2015;290:20774-81 pubmed publisher

Shirai Y, Mori A, Nakahara T, Sakamoto K, Ishii K. Deferiprone Protects against Photoreceptor Degeneration Induced by Tunicamycin in the Rat Retina. Biol Pharm Bull. 2015;38:1076-80 pubmed publisher

Tzankov A, Leu N, Muenst S, Juskevicius D, Klingbiel D, Mamot C, et al. Multiparameter analysis of homogeneously R-CHOP-treated diffuse large B cell lymphomas identifies CD5 and FOXP1 as relevant prognostic biomarkers: report of the prospective SAKK 38/07 study. J Hematol Oncol. 2015;8:70 pubmed publisher

Mota L, Cruz B, Brenol C, Pollak D, Pinheiro G, Laurindo I, et al. [Safe use of biological therapies for the treatment of rheumatoid arthritis and spondyloarthritides]. Rev Bras Reumatol. 2015;55:281-309 pubmed publisher

Vlachodimitropoulou Koumoutsea E, Garbowski M, Porter J. Synergistic intracellular iron chelation combinations: mechanisms and conditions for optimizing iron mobilization. Br J Haematol. 2015;170:874-83 pubmed publisher

Kurokawa T, Fukami T, Nakajima M. Characterization of Species Differences in Tissue Diltiazem Deacetylation Identifies Ces2a as a Rat-Specific Diltiazem Deacetylase. Drug Metab Dispos. 2015;43:1218-25 pubmed publisher

Khadjavi A, Magnetto C, Panariti A, Argenziano M, Gulino G, Rivolta I, et al. Chitosan-shelled oxygen-loaded nanodroplets abrogate hypoxia dysregulation of human keratinocyte gelatinases and inhibitors: New insights for chronic wound healing. Toxicol Appl Pharmacol. 2015;286:198-206 pubmed publisher

Harvey K, Xu Z, Pavlina T, Zaloga G, Siddiqui R. Modulation of endothelial cell integrity and inflammatory activation by commercial lipid emulsions. Lipids Health Dis. 2015;14:9 pubmed publisher

Li Y, Lein P, Ford G, Liu C, Stovall K, White T, et al. Neuregulin-1 inhibits neuroinflammatory responses in a rat model of organophosphate-nerve agent-induced delayed neuronal injury. J Neuroinflammation. 2015;12:64 pubmed publisher

Haschka D, Nairz M, Demetz E, Wienerroither S, Decker T, Weiss G. Contrasting regulation of macrophage iron homeostasis in response to infection with Listeria monocytogenes depending on localization of bacteria. Metallomics. 2015;7:1036-45 pubmed publisher

Saito Y, Kamita S, Hammock B, Kunimi Y, Inoue M, Nakai M. Juvenile hormone (JH) esterase activity but not JH epoxide hydrolase activity is downregulated in larval Adoxophyes honmai following nucleopolyhedroviruses infection. J Insect Physiol. 2015;80:71-80 pubmed publisher

Tancharoen S, Matsuyama T, Kawahara K, Tanaka K, Lee L, Machigashira M, et al. Cleavage of host cytokeratin-6 by lysine-specific gingipain induces gingival inflammation in periodontitis patients. PLoS ONE. 2015;10:e0117775 pubmed publisher

Akparov V, Timofeev V, Khaliullin I, Å vedas V, Chestukhina G, Kuranova I. Structural insights into the broad substrate specificity of carboxypeptidase T from Thermoactinomyces vulgaris. FEBS J. 2015;282:1214-24 pubmed publisher

McGoldrick C, Jiang Y, Brannon M, Krishnan K, Stone W. In vitro evaluation of novel N-acetylalaninate prodrugs that selectively induce apoptosis in prostate cancer cells. BMC Cancer. 2014;14:675 pubmed publisher

Deshpande L, Phillips K, Huang B, Delorenzo R. Chronic behavioral and cognitive deficits in a rat survival model of paraoxon toxicity. Neurotoxicology. 2014;44:352-7 pubmed publisher

Oriel S, Dori A, Kofman O. Postnatal diisopropylfluorophosphate enhances conditioned vigilance in adult BALB/c and C57BL/6 mice and alters expression of acetylcholinesterase splice variants. Behav Pharmacol. 2014;25:661-72 pubmed publisher

Roychaudhuri R, Hergrueter A, Polverino F, Laucho Contreras M, Gupta K, Borregaard N, et al. ADAM9 is a novel product of polymorphonuclear neutrophils: regulation of expression and contributions to extracellular matrix protein degradation during acute lung injury. J Immunol. 2014;193:2469-82 pubmed publisher

Ferchmin P, Andino M, Reyes Salaman R, Alves J, Velez Roman J, Cuadrado B, et al. 4R-cembranoid protects against diisopropylfluorophosphate-mediated neurodegeneration. Neurotoxicology. 2014;44:80-90 pubmed publisher

Deshpande L, Carter D, Phillips K, Blair R, Delorenzo R. Development of status epilepticus, sustained calcium elevations and neuronal injury in a rat survival model of lethal paraoxon intoxication. Neurotoxicology. 2014;44:17-26 pubmed publisher

Rezk P, Zdenka P, Sabnekar P, Kajih T, Mata D, Wrobel C, et al. An in vitro and in vivo evaluation of the efficacy of recombinant human liver prolidase as a catalytic bioscavenger of chemical warfare nerve agents. Drug Chem Toxicol. 2015;38:37-43 pubmed publisher

Benabent M, Vilanova E, Mangas I, Sogorb M, Estevez J. Interaction between substrates suggests a relationship between organophosphorus-sensitive phenylvalerate- and acetylcholine-hydrolyzing activities in chicken brain. Toxicol Lett. 2014;230:132-8 pubmed publisher

Mangas I, Vilanova E, Benabent M, Estevez J. Separating esterase targets of organophosphorus compounds in the brain by preparative chromatography. Toxicol Lett. 2014;225:167-76 pubmed publisher

Iudin M, Chepur S, Bykov V, Kurpiakova A, Subbotina S, Nikiforov A, et al. [Specific features of the anticonvulsant effect of memantine in mice intoxicated with a model organic phosphate]. Eksp Klin Farmakol. 2013;76:3-5 pubmed

Brewer K, Troendle M, Pekman L, Meggs W. Naltrexone prevents delayed encephalopathy in rats poisoned with the sarin analogue diisopropylflurophosphate. Am J Emerg Med. 2013;31:676-9 pubmed publisher

Estevez J, Mangas I, Sogorb M, Vilanova E. Interactions of neuropathy inducers and potentiators/promoters with soluble esterases. Chem Biol Interact. 2013;203:245-50 pubmed publisher

López Granero C, Cañadas F, Cardona D, Yu Y, Giménez E, Lozano R, et al. Chlorpyrifos-, diisopropylphosphorofluoridate-, and parathion-induced behavioral and oxidative stress effects: are they mediated by analogous mechanisms of action?. Toxicol Sci. 2013;131:206-16 pubmed publisher

Aleti V, Reddy G, Parikh K, Arun P, Chilukuri N. Persistent and high-level expression of human liver prolidase in vivo in mice using adenovirus. Chem Biol Interact. 2013;203:191-5 pubmed publisher

Li Y, Lein P, Liu C, Bruun D, Giulivi C, Ford G, et al. Neuregulin-1 is neuroprotective in a rat model of organophosphate-induced delayed neuronal injury. Toxicol Appl Pharmacol. 2012;262:194-204 pubmed publisher

Todorovic M, Cowan M, Balint C, Sun C, Kapur J. Characterization of status epilepticus induced by two organophosphates in rats. Epilepsy Res. 2012;101:268-76 pubmed publisher

Eigenbrot C, Ultsch M, Lipari M, Moran P, Lin S, Ganesan R, et al. Structural and functional analysis of HtrA1 and its subdomains. Structure. 2012;20:1040-50 pubmed publisher

Zheng N, Fung E, Buzescu A, Arnold M, Zeng J. Esterase inhibitors as ester-containing drug stabilizers and their hydrolytic products: potential contributors to the matrix effects on bioanalysis by liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 2012;26:1291-304 pubmed publisher

Gebinoga M, Mai P, Donahue M, Kittler M, Cimalla I, Lübbers B, et al. Nerve cell response to inhibitors recorded with an aluminum-galliumnitride/galliumnitride field-effect transistor. J Neurosci Methods. 2012;206:195-9 pubmed publisher

Belinskaya T, Pattabiraman N, diTargiani R, Choi M, Saxena A. Differences in amino acid residues in the binding pockets dictate substrate specificities of mouse senescence marker protein-30, human paraoxonase1, and squid diisopropylfluorophosphatase. Biochim Biophys Acta. 2012;1824:701-10 pubmed publisher

Bhattacharjee A, Marek E, Le H, Gordon R. Discovery of non-oxime reactivators using an in silico pharmacophore model of oxime reactivators of OP-inhibited acetylcholinesterase. Eur J Med Chem. 2012;49:229-38 pubmed publisher

Lin T, Duek O, Dori A, Kofman O. Differential long term effects of early diisopropylfluorophosphate exposure in Balb/C and C57Bl/J6 mice. Int J Dev Neurosci. 2012;30:113-20 pubmed publisher

Kamita S, Samra A, Liu J, Cornel A, Hammock B. Juvenile hormone (JH) esterase of the mosquito Culex quinquefasciatus is not a target of the JH analog insecticide methoprene. PLoS ONE. 2011;6:e28392 pubmed publisher

Xue Y, Ha Y. Catalytic mechanism of rhomboid protease GlpG probed by 3,4-dichloroisocoumarin and diisopropyl fluorophosphonate. J Biol Chem. 2012;287:3099-107 pubmed publisher

Costante M, Biggemann L, Alamneh Y, Soojhawon I, Short R, Nigam S, et al. Hydrolysis potential of recombinant human skin and kidney prolidase against diisopropylfluorophosphate and sarin by in vitro analysis. Toxicol In Vitro. 2012;26:182-8 pubmed publisher

Lee B, Kim M, Song H. Structural insights into the conformational diversity of ClpP from Bacillus subtilis. Mol Cells. 2011;32:589-95 pubmed publisher

Terry A, Beck W, Warner S, Vandenhuerk L, Callahan P. Chronic impairments in spatial learning and memory in rats previously exposed to chlorpyrfos or diisopropylfluorophosphate. Neurotoxicol Teratol. 2012;34:1-8 pubmed publisher

Tarhoni M, Vigneswara V, Smith M, Anderson S, Wigmore P, Lees J, et al. Detection, quantification, and microlocalisation of targets of pesticides using microchannel plate autoradiographic imagers. Molecules. 2011;16:8535-51 pubmed publisher

Lee M, Vishnyakov A, Gor G, Neimark A. Interactions of phosphororganic agents with water and components of polyelectrolyte membranes. J Phys Chem B. 2011;115:13617-23 pubmed publisher

Gotor R, Costero A, Gil S, Parra M, Martínez Máñez R, Sancenon F. A molecular probe for the highly selective chromogenic detection of DFP, a mimic of Sarin and Soman nerve agents. Chemistry. 2011;17:11994-7 pubmed publisher

Kadriu B, Gocel J, Larson J, Guidotti A, Davis J, Nambiar M, et al. Absence of tolerance to the anticonvulsant and neuroprotective effects of imidazenil against DFP-induced seizure and neuronal damage. Neuropharmacology. 2011;61:1463-9 pubmed publisher

Damodaran T, Attia M, Abou Donia M. Early differential cell death and survival mechanisms initiate and contribute to the development of OPIDN: a study of molecular, cellular, and anatomical parameters. Toxicol Appl Pharmacol. 2011;256:348-59 pubmed publisher

Suzuki E, Nakai D, Yamamura N, Kobayashi N, Okazaki O, Izumi T. Inhibition mechanism of carbapenem antibiotics on acylpeptide hydrolase, a key enzyme in the interaction with valproic acid. Xenobiotica. 2011;41:958-63 pubmed publisher

Mangas I, Vilanova E, Estevez J. Kinetics of the inhibitory interaction of organophosphorus neuropathy inducers and non-inducers in soluble esterases in the avian nervous system. Toxicol Appl Pharmacol. 2011;256:360-8 pubmed publisher

Li Y, Lein P, Liu C, Bruun D, Tewolde T, Ford G, et al. Spatiotemporal pattern of neuronal injury induced by DFP in rats: a model for delayed neuronal cell death following acute OP intoxication. Toxicol Appl Pharmacol. 2011;253:261-9 pubmed publisher

Terry A, Buccafusco J, Gearhart D, Beck W, Middlemore Risher M, Truan J, et al. Repeated, intermittent exposures to diisopropylfluorophosphate in rats: protracted effects on cholinergic markers, nerve growth factor-related proteins, and cognitive function. Neuroscience. 2011;176:237-53 pubmed publisher

Deshpande L, Carter D, Blair R, Delorenzo R. Development of a prolonged calcium plateau in hippocampal neurons in rats surviving status epilepticus induced by the organophosphate diisopropylfluorophosphate. Toxicol Sci. 2010;116:623-31 pubmed publisher

Dutta S, Malla R, Bandyopadhyay S, Spilling C, Dupureur C. Synthesis and kinetic analysis of some phosphonate analogs of cyclophostin as inhibitors of human acetylcholinesterase. Bioorg Med Chem. 2010;18:2265-2274 pubmed publisher

Ding S, Carr J, Carlson J, Tong L, Xue W, Li Y, et al. Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin. Chem Res Toxicol. 2008;21:1787-94 pubmed publisher

Butini S, Campiani G, Borriello M, Gemma S, Panico A, Persico M, et al. Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors. J Med Chem. 2008;51:3154-70 pubmed publisher

Tong L, Phan T, Robinson K, Babusis D, Strab R, Bhoopathy S, et al. Effects of human immunodeficiency virus protease inhibitors on the intestinal absorption of tenofovir disoproxil fumarate in vitro. Antimicrob Agents Chemother. 2007;51:3498-504 pubmed

Birkus G, Wang R, Liu X, Kutty N, MacArthur H, Cihlar T, et al. Cathepsin A is the major hydrolase catalyzing the intracellular hydrolysis of the antiretroviral nucleotide phosphonoamidate prodrugs GS-7340 and GS-9131. Antimicrob Agents Chemother. 2007;51:543-50 pubmed

Vogel J, Keating G, Buchholz B. Protein binding of isofluorophate in vivo after coexposure to multiple chemicals. Environ Health Perspect. 2002;110 Suppl 6:1031-6 pubmed

Oda T, Komatsu N, Muramatsu T. Diisopropylfluorophosphate (DFP) inhibits ricin-induced apoptosis of MDCK cells. Biosci Biotechnol Biochem. 1998;62:325-33 pubmed

Raab S. Diisopropylfluorophosphate-P32 (DFP-P32) as a label for granulocytes. Adv Tracer Methodol. 1965;2:261-6 pubmed

Wilson B, Walker C. Regulation of newly synthesized acetylcholinesterase in muscle cultures treated with diisopropylfluorophosphate. Proc Natl Acad Sci U S A. 1974;71:3194-8 pubmed