This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt
catalog :
D0627
citations: 74
Reference
Cardner M, Yalcınkaya M, Goetze S, Luca E, Balaz M, Hunjadi M, et al. Structure-function relationships of HDL in diabetes and coronary heart disease. JCI Insight. 2020;5: pubmed publisher
Woodley P, Min Q, Li Y, Mulvey N, Parkinson D, Dun X. Distinct VIP and PACAP Functions in the Distal Nerve Stump During Peripheral Nerve Regeneration. Front Neurosci. 2019;13:1326 pubmed publisher
Leitner D, Ramamoorthy M, Dejosez M, Zwaka T. Immature mDA neurons ameliorate motor deficits in a 6-OHDA Parkinson's disease mouse model and are functional after cryopreservation. Stem Cell Res. 2019;41:101617 pubmed publisher
Larsen H, Hansen S, Mikkelsen J, Hyttel P, Stummann T. Alpha7 nicotinic acetylcholine receptors and neural network synaptic transmission in human induced pluripotent stem cell-derived neurons. Stem Cell Res. 2019;41:101642 pubmed publisher
Wang X, Williams D, Muller I, Lemieux M, Dukart R, Maia I, et al. Tau interactome analyses in CRISPR-Cas9 engineered neuronal cells reveal ATPase-dependent binding of wild-type but not P301L Tau to non-muscle myosins. Sci Rep. 2019;9:16238 pubmed publisher
Zielinska A, Bellou E, Sharma N, Frombach A, Seres K, Gruhn J, et al. Meiotic Kinetochores Fragment into Multiple Lobes upon Cohesin Loss in Aging Eggs. Curr Biol. 2019;29:3749-3765.e7 pubmed publisher
Fitzgerald H, Dhakal P, Behura S, Schust D, Spencer T. Self-renewing endometrial epithelial organoids of the human uterus. Proc Natl Acad Sci U S A. 2019;116:23132-23142 pubmed publisher
Ranjan P, Awasthi M, Snell W. Transient Internalization and Microtubule-Dependent Trafficking of a Ciliary Signaling Receptor from the Plasma Membrane to the Cilium. Curr Biol. 2019;29:2942-2947.e2 pubmed publisher
Gao F, Elliott N, Ho J, Sharp A, Shokhirev M, Hargreaves D. Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4. Mol Cell. 2019;75:891-904.e7 pubmed publisher
Praena B, Bello Morales R, de Castro F, Lopez Guerrero J. Amidic derivatives of valproic acid, valpromide and valnoctamide, inhibit HSV-1 infection in oligodendrocytes. Antiviral Res. 2019;168:91-99 pubmed publisher
Anchan A, Kalogirou Baldwin P, Johnson R, Kho D, Joseph W, Hucklesby J, et al. Real-Time Measurement of Melanoma Cell-Mediated Human Brain Endothelial Barrier Disruption Using Electric Cell-Substrate Impedance Sensing Technology. Biosensors (Basel). 2019;9: pubmed publisher
Chen Y, Wang J, Fan Y, Qin C, Xia X, Johnson J, et al. Absence of the long noncoding RNA H19 results in aberrant ovarian STAR and progesterone production. Mol Cell Endocrinol. 2019;490:15-20 pubmed publisher
Zhang Q, Hsia S, Martin Caraballo M. Regulation of T-type Ca2+ channel expression by interleukin-6 in sensory-like ND7/23 cells post-herpes simplex virus (HSV-1) infection. J Neurochem. 2019;151:238-254 pubmed publisher
Yun C, Hong S, Lee Y, Lee J, Jung D, Kim G, et al. Nuclear Entry of CRTC1 as Druggable Target of Acquired Pigmentary Disorder. Theranostics. 2019;9:646-660 pubmed publisher
Hwang S, Somatilaka B, Badgandi H, Palicharla V, Walker R, Shelton J, et al. Tulp3 Regulates Renal Cystogenesis by Trafficking of Cystoproteins to Cilia. Curr Biol. 2019;29:790-802.e5 pubmed publisher
Narayanan A, Meriin A, Andrews J, Spille J, Sherman M, Cisse I. A first order phase transition mechanism underlies protein aggregation in mammalian cells. elife. 2019;8: pubmed publisher
Marton R, Miura Y, Sloan S, Li Q, Revah O, Levy R, et al. Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures. Nat Neurosci. 2019;22:484-491 pubmed publisher
Melamed Z, López Erauskin J, Baughn M, Zhang O, Drenner K, Sun Y, et al. Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration. Nat Neurosci. 2019;22:180-190 pubmed publisher
Edwards T, Bloom D. Lund Human Mesencephalic (LUHMES) Neuronal Cell Line Supports Herpes Simplex Virus 1 Latency In Vitro. J Virol. 2019;93: pubmed publisher
Abe T, La T, Miyagaki Y, Oya E, Wei F, Sumida K, et al. Phosphorylation of cortactin by cyclin-dependent kinase 5 modulates actin bundling by the dynamin 1-cortactin ring-like complex and formation of filopodia and lamellipodia in NG108-15 glioma-derived cells. Int J Oncol. 2019;54:550-558 pubmed publisher
Chen Y, Liu Y, Liu Y, Lee Y, Huang H, Chen Y, et al. Nitrite protects neurons against hypoxic damage through <i>S</i>-nitrosylation of caspase-6. Antioxid Redox Signal. 2018;: pubmed publisher
Gu A, Kho D, Johnson R, Graham E, O Carroll S. In Vitro Wounding Models Using the Electric Cell-Substrate Impedance Sensing (ECIS)-Zθ Technology. Biosensors (Basel). 2018;8: pubmed publisher
Kutsche L, Gysi D, Fallmann J, Lenk K, Petri R, Swiersy A, et al. Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis. Cell Syst. 2018;7:438-452.e8 pubmed publisher
Jan A, Jansonius B, Delaidelli A, Bhanshali F, An Y, Ferreira N, et al. Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity. Acta Neuropathol Commun. 2018;6:54 pubmed publisher
Konermann S, Lotfy P, Brideau N, Oki J, Shokhirev M, Hsu P. Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors. Cell. 2018;173:665-676.e14 pubmed publisher
Hsu F, Spannl S, Ferguson C, Hyman A, Parton R, Zerial M. Rab5 and Alsin regulate stress-activated cytoprotective signaling on mitochondria. elife. 2018;7: pubmed publisher
Edwards T, Bloom D, Fisher C. The ATM and Rad3-Related (ATR) Protein Kinase Pathway Is Activated by Herpes Simplex Virus 1 and Required for Efficient Viral Replication. J Virol. 2018;92: pubmed publisher
Clift D, McEwan W, Labzin L, Konieczny V, Mogessie B, James L, et al. A Method for the Acute and Rapid Degradation of Endogenous Proteins. Cell. 2017;171:1692-1706.e18 pubmed publisher
Adams N, Vasquez Y, Mo Q, Gibbons W, Kovanci E, DeMayo F. WNK lysine deficient protein kinase 1 regulates human endometrial stromal cell decidualization, proliferation, and migration in part through mitogen-activated protein kinase 7. Biol Reprod. 2017;97:400-412 pubmed publisher
Kho D, Johnson R, O Carroll S, Angel C, Graham E. Biosensor Technology Reveals the Disruption of the Endothelial Barrier Function and the Subsequent Death of Blood Brain Barrier Endothelial Cells to Sodium Azide and Its Gaseous Products. Biosensors (Basel). 2017;7: pubmed publisher
Long Q, Luo Q, Wang K, Bates A, Shetty A. Mash1-dependent Notch Signaling Pathway Regulates GABAergic Neuron-Like Differentiation from Bone Marrow-Derived Mesenchymal Stem Cells. Aging Dis. 2017;8:301-313 pubmed publisher
Fernando R, Cotter L, Perrin Tricaud C, Berthelot J, Bartolami S, Pereira J, et al. Optimal myelin elongation relies on YAP activation by axonal growth and inhibition by Crb3/Hippo pathway. Nat Commun. 2016;7:12186 pubmed publisher
Nandi S, Zheng H, Sharma N, Shahshahan H, Patel K, Mishra P. Lack of miR-133a Decreases Contractility of Diabetic Hearts: A Role for Novel Cross Talk Between Tyrosine Aminotransferase and Tyrosine Hydroxylase. Diabetes. 2016;65:3075-90 pubmed publisher
Abbassi L, Malki S, Cockburn K, Macaulay A, Robert C, Rossant J, et al. Multiple Mechanisms Cooperate to Constitutively Exclude the Transcriptional Co-Activator YAP from the Nucleus During Murine Oogenesis. Biol Reprod. 2016;94:102 pubmed publisher
Gan M, Moussaud S, Jiang P, McLean P. Extracellular ATP induces intracellular alpha-synuclein accumulation via P2X1 receptor-mediated lysosomal dysfunction. Neurobiol Aging. 2015;36:1209-20 pubmed publisher
Rodriguez Perez A, Borrajo A, Valenzuela R, Lanciego J, Labandeira Garcia J. Critical period for dopaminergic neuroprotection by hormonal replacement in menopausal rats. Neurobiol Aging. 2015;36:1194-208 pubmed publisher
Raff H, Gehrand A, Bruder E, Hoffman M, Engeland W, Moreno C. Renin knockout rat: control of adrenal aldosterone and corticosterone synthesis in vitro and adrenal gene expression. Am J Physiol Regul Integr Comp Physiol. 2015;308:R73-7 pubmed publisher
Abiuso A, Berensztein E, Pagotto R, Pereyra E, Medina V, Martinel Lamas D, et al. H4 histamine receptors inhibit steroidogenesis and proliferation in Leydig cells. J Endocrinol. 2014;223:241-53 pubmed publisher
Lee J, Lee J, Moon E. HeLa human cervical cancer cell migration is inhibited by treatment with dibutyryl-cAMP. Anticancer Res. 2014;34:3447-55 pubmed
Borrajo A, Rodriguez Perez A, Villar Cheda B, Guerra M, Labandeira Garcia J. Inhibition of the microglial response is essential for the neuroprotective effects of Rho-kinase inhibitors on MPTP-induced dopaminergic cell death. Neuropharmacology. 2014;85:1-8 pubmed publisher
Amadoro G, Corsetti V, Sancesario G, Lubrano A, Melchiorri G, Bernardini S, et al. Cerebrospinal fluid levels of a 20-22 kDa NH2 fragment of human tau provide a novel neuronal injury biomarker in Alzheimer's disease and other dementias. J Alzheimers Dis. 2014;42:211-26 pubmed publisher
Cicerchi C, Li N, Kratzer J, Garcia G, Roncal Jimenez C, Tanabe K, et al. Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: evolutionary implications of the uricase loss in hominids. FASEB J. 2014;28:3339-50 pubmed publisher
Liu G, Anisman H, Bobyn J, Hayley S. Interaction between nonviral reprogrammed fibroblast stem cells and trophic factors for brain repair. Mol Neurobiol. 2014;50:673-84 pubmed publisher
Korytowski W, Wawak K, Pabisz P, Schmitt J, Girotti A. Macrophage mitochondrial damage from StAR transport of 7-hydroperoxycholesterol: implications for oxidative stress-impaired reverse cholesterol transport. FEBS Lett. 2014;588:65-70 pubmed publisher
Iwase K, Ishihara A, Yoshimura S, Andoh Y, Kato M, Seki N, et al. The secretogranin II gene is a signal integrator of glutamate and dopamine inputs. J Neurochem. 2014;128:233-45 pubmed publisher
Yano T. [Cellular and molecular mechanisms in drug-induced nephrotoxicity and its prevention]. Nihon Yakurigaku Zasshi. 2013;142:172-7 pubmed
Calejo A, Jorgacevski J, Kucka M, Kreft M, Gonçalves P, Stojilkovic S, et al. cAMP-mediated stabilization of fusion pores in cultured rat pituitary lactotrophs. J Neurosci. 2013;33:8068-78 pubmed publisher
Manna P, Cohen Tannoudji J, Counis R, Garner C, Huhtaniemi I, Kraemer F, et al. Mechanisms of action of hormone-sensitive lipase in mouse Leydig cells: its role in the regulation of the steroidogenic acute regulatory protein. J Biol Chem. 2013;288:8505-18 pubmed publisher
Fu J, Song W, Zong S, Koide S, Miao S, Wang L. Dynamic alterations in the expression and localization of ACTL7a during capacitation in mouse spermatozoa. Fertil Steril. 2013;99:882-8 pubmed publisher
Yin F, Tian Z, Liu S, Zhao Q, Wang R, Shen L, et al. Transplantation of human retinal pigment epithelium cells in the treatment for Parkinson disease. CNS Neurosci Ther. 2012;18:1012-20 pubmed publisher
Han Y, Sun H, Li P, Gao Q, Zhou Y, Zhang F, et al. Angiotensin-(1-7) in paraventricular nucleus modulates sympathetic activity and cardiac sympathetic afferent reflex in renovascular hypertensive rats. PLoS ONE. 2012;7:e48966 pubmed publisher
Valero T, Moschopoulou G, Mayor López L, Kintzios S. Moderate superoxide production is an early promoter of mitochondrial biogenesis in differentiating N2a neuroblastoma cells. Neurochem Int. 2012;61:1333-43 pubmed publisher
Liu D, Liu M, Baker H. Defective protein kinase A and C pathways are common causes of disordered zona pellucida (ZP)--induced acrosome reaction in normozoospermic infertile men with normal sperm-ZP binding. Fertil Steril. 2013;99:86-91 pubmed publisher
Myeku N, Wang H, Figueiredo Pereira M. cAMP stimulates the ubiquitin/proteasome pathway in rat spinal cord neurons. Neurosci Lett. 2012;527:126-31 pubmed publisher
Boczek T, Lisek M, Kowalski A, Pikula S, Niewiarowska J, Wiktorska M, et al. Downregulation of PMCA2 or PMCA3 reorganizes Ca(2+) handling systems in differentiating PC12 cells. Cell Calcium. 2012;52:433-44 pubmed publisher
Wieschhaus A, Khan A, Zaidi A, Rogalin H, Hanada T, Liu F, et al. Calpain-1 knockout reveals broad effects on erythrocyte deformability and physiology. Biochem J. 2012;448:141-52 pubmed publisher
Coon S, Munson P, Cherukuri P, Sugden D, Rath M, Møller M, et al. Circadian changes in long noncoding RNAs in the pineal gland. Proc Natl Acad Sci U S A. 2012;109:13319-24 pubmed publisher
Li Y, Wang F, Zhang X, Qi Z, Tang M, Szeto C, et al. ?-Adrenergic stimulation increases Cav3.1 activity in cardiac myocytes through protein kinase A. PLoS ONE. 2012;7:e39965 pubmed publisher
Li Y, Anand Srivastava M. Implication of multiple signaling pathways in the regulation of angiotensin II induced enhanced expression of Giα proteins in vascular smooth muscle cells. Can J Physiol Pharmacol. 2012;90:1105-16 pubmed publisher
Sun P, Liu Y, Ying H, Li S. Action of db-cAMP on the bystander effect and chemosensitivity through connexin 43 and Bcl-2-mediated pathways in medulloblastoma cells. Oncol Rep. 2012;28:969-76 pubmed publisher
Chen Y, Lin P, Wong R, Wu Y, Hsu H, Tsai M, et al. Minocycline inhibits D-amphetamine-elicited action potential bursts in a central snail neuron. Neuroscience. 2012;223:412-28 pubmed publisher
Bhattacharjee R, Xiang W, Wang Y, Zhang X, Billiar T. cAMP prevents TNF-induced apoptosis through inhibiting DISC complex formation in rat hepatocytes. Biochem Biophys Res Commun. 2012;423:85-90 pubmed publisher
Palmer E, Gray L, Stott M, Bowen D, van den Berg C. Roles of promoter and 3' untranslated motifs in expression of the human C5a receptor. Mol Immunol. 2012;52:88-95 pubmed publisher
Hwang J, Kelly G. GATA6 and FOXA2 regulate Wnt6 expression during extraembryonic endoderm formation. Stem Cells Dev. 2012;21:3220-32 pubmed publisher
Fujii T, Takada Takatori Y, Kawashima K. Regulatory mechanisms of acetylcholine synthesis and release by T cells. Life Sci. 2012;91:981-5 pubmed publisher
Fang K, Liu Y, Lin C, Fan S, Tsai C, Tzeng S. Mps one binder 2 gene upregulation in the stellation of astrocytes induced by cAMP-dependent pathway. J Cell Biochem. 2012;113:3019-28 pubmed publisher
Savchenko V. Regulation of NADPH oxidase gene expression with PKA and cytokine IL-4 in neurons and microglia. Neurotox Res. 2013;23:201-13 pubmed publisher
Asano H, Miyamoto A, Nakao M, Wakaki C, Iida T, Funakami Y, et al. Differential expression of the 5-HT(3A) and 5-HT(3B) receptor in differentiated NG108-15 cells. Neurochem Res. 2012;37:1738-46 pubmed publisher
Ren Y, D Ambrosio M, Wang H, Falck J, Peterson E, Garvin J, et al. Mechanisms of carbon monoxide attenuation of tubuloglomerular feedback. Hypertension. 2012;59:1139-44 pubmed publisher
Fredsted A, Gissel H, Ortenblad N, Clausen T. Effects of ??-agonists on force during and following anoxia in rat extensor digitorum longus muscle. J Appl Physiol (1985). 2012;112:2057-67 pubmed publisher
Ueberham U, Hilbrich I, Ueberham E, Rohn S, Glöckner P, Dietrich K, et al. Transcriptional control of cell cycle-dependent kinase 4 by Smad proteins--implications for Alzheimer's disease. Neurobiol Aging. 2012;33:2827-40 pubmed publisher
Yamauchi J, Miyamoto Y, Hamasaki H, Sanbe A, Kusakawa S, Nakamura A, et al. The atypical Guanine-nucleotide exchange factor, dock7, negatively regulates schwann cell differentiation and myelination. J Neurosci. 2011;31:12579-92 pubmed publisher
Zhang M, Fei X, He Y, Yang G, Mei Y. Bradykinin inhibits the transient outward K+ current in mouse Schwann cells via the cAMP/PKA pathway. Am J Physiol Cell Physiol. 2009;296:C1364-72 pubmed publisher
Fregien N, White L, Bunge M, Wood P. Forskolin increases neuregulin receptors in human Schwann cells without increasing receptor mRNA. Glia. 2005;49:24-35 pubmed
product information
Catalog Number :
D0627
Product Name :
N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
≥96% (HPLC), powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA