This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
R(+)-SCH-23390 hydrochloride
catalog :
D054
citations: 22
Reference
Jha U, Thirumalai V. Neuromodulatory Selection of Motor Neuron Recruitment Patterns in a Visuomotor Behavior Increases Speed. Curr Biol. 2020;30:788-801.e3 pubmed publisher
Li Q, Zhang B, Cao H, Liu W, Guo F, Shen F, et al. Oxytocin Exerts Antidepressant-like effect by potentiating dopaminergic synaptic transmission in the mPFC. Neuropharmacology. 2020;162:107836 pubmed publisher
Su P, Lai T, Lee F, Abela A, Fletcher P, Liu F. Disruption of SynGAP-dopamine D1 receptor complexes alters actin and microtubule dynamics and impairs GABAergic interneuron migration. Sci Signal. 2019;12: pubmed publisher
Dokovna L, Li G, Wood R. Anabolic-androgenic steroids and cognitive effort discounting in male rats. Horm Behav. 2019;113:13-20 pubmed publisher
Suh Y, Noh S, Lee S, Suh B, Lee S, Choi J, et al. Dopamine D1 Receptor (D1R) Expression Is Controlled by a Transcriptional Repressor Complex Containing DISC1. Mol Neurobiol. 2019;: pubmed publisher
Messias J, Paula J, Grutter A, Bshary R, Soares M. Dopamine disruption increases negotiation for cooperative interactions in a fish. Sci Rep. 2016;6:20817 pubmed publisher
Tran S, Nowicki M, Muraleetharan A, Chatterjee D, Gerlai R. Differential effects of acute administration of SCH-23390, a D₁ receptor antagonist, and of ethanol on swimming activity, anxiety-related responses, and neurochemistry of zebrafish. Psychopharmacology (Berl). 2015;232:3709-18 pubmed publisher
McNamara C, Tejero Cantero Ã, Trouche S, Campo Urriza N, Dupret D. Dopaminergic neurons promote hippocampal reactivation and spatial memory persistence. Nat Neurosci. 2014;17:1658-60 pubmed publisher
Naumenko V, Kondaurova E, Bazovkina D, Tsybko A, Ilchibaeva T, Khotskin N, et al. Effect of GDNF on depressive-like behavior, spatial learning and key genes of the brain dopamine system in genetically predisposed to behavioral disorders mouse strains. Behav Brain Res. 2014;274:1-9 pubmed publisher
Fish E, Diberto J, Krouse M, Robinson J, Malanga C. Different contributions of dopamine D1 and D2 receptor activity to alcohol potentiation of brain stimulation reward in C57BL/6J and DBA/2J mice. J Pharmacol Exp Ther. 2014;350:322-9 pubmed publisher
Kikuchi N, Irifune M, Shimizu Y, Yoshida K, Morita K, Kanematsu T, et al. Selective blockade of N-methyl-D-aspartate channels in combination with dopamine receptor antagonism induces loss of the righting reflex in mice, but not immobility. Psychopharmacology (Berl). 2015;232:39-46 pubmed publisher
Péczely L, Ollmann T, László K, Kovács A, Gálosi R, Szabo Á, et al. Role of D1 dopamine receptors of the ventral pallidum in inhibitory avoidance learning. Behav Brain Res. 2014;270:131-6 pubmed publisher
Steinberg E, Boivin J, Saunders B, Witten I, Deisseroth K, Janak P. Positive reinforcement mediated by midbrain dopamine neurons requires D1 and D2 receptor activation in the nucleus accumbens. PLoS ONE. 2014;9:e94771 pubmed publisher
Fedotova J. Effects of SCH-23390 in combination with a low dose of 17?-estradiol on anxiety-like behavior in ovariectomized rats. Biomed Res Int. 2014;2014:847821 pubmed publisher
Clark A, McCorvy J, Watts V, Nichols D. Assessment of dopamine D₁ receptor affinity and efficacy of three tetracyclic conformationally-restricted analogs of SKF38393. Bioorg Med Chem. 2011;19:5420-31 pubmed publisher
Souza B, Romano Silva M, Tropepe V. Dopamine D2 receptor activity modulates Akt signaling and alters GABAergic neuron development and motor behavior in zebrafish larvae. J Neurosci. 2011;31:5512-25 pubmed publisher
Hayashida Y, Rodríguez C, Ogata G, Partida G, Oi H, Stradleigh T, et al. Inhibition of adult rat retinal ganglion cells by D1-type dopamine receptor activation. J Neurosci. 2009;29:15001-16 pubmed publisher
Yuan J, Johnson R, Huang R, Wichterman J, Jiang H, Hayton K, et al. Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nat Chem Biol. 2009;5:765-71 pubmed publisher
Diamandis P, Wildenhain J, Clarke I, Sacher A, Graham J, Bellows D, et al. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol. 2007;3:268-73 pubmed
Iorio L, Barnett A, Leitz F, Houser V, Korduba C. SCH 23390, a potential benzazepine antipsychotic with unique interactions on dopaminergic systems. J Pharmacol Exp Ther. 1983;226:462-8 pubmed
O Boyle K, Waddington J. [3H]SCH 23390 binding to human putamen D-1 dopamine receptors: stereochemical and structure-affinity relationships among 1-phenyl-1H-3-benzazepine derivatives as a guide to D-1 receptor topography. J Neurochem. 1987;48:1039-42 pubmed
Sidhu A, Van Oene J, Dandridge P, Kaiser C, Kebabian J. [125I]SCH 23982: the ligand of choice for identifying the D-1 dopamine receptor. Eur J Pharmacol. 1986;128:213-20 pubmed
product information
Catalog Number :
D054
Product Name :
R(+)-SCH-23390 hydrochloride
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA