This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
β-Secretase (BACE1) Activity Detection Kit (Fluorescent)
catalog :
CS0010
citations: 17
Reference
Tripathi A, Choubey P, Sharma P, Seth A, Saraf P, Shrivastava S. Design, synthesis, and biological evaluation of ferulic acid based 1,3,4-oxadiazole hybrids as multifunctional therapeutics for the treatment of Alzheimer's disease. Bioorg Chem. 2020;95:103506 pubmed publisher
Tripathi A, Choubey P, Sharma P, Seth A, Tripathi P, Tripathi M, et al. Design and development of molecular hybrids of 2-pyridylpiperazine and 5-phenyl-1,3,4-oxadiazoles as potential multifunctional agents to treat Alzheimer's disease. Eur J Med Chem. 2019;183:111707 pubmed publisher
Sharma P, Tripathi A, Tripathi P, Singh S, Singh S, Shrivastava S. Novel Molecular Hybrids of N-Benzylpiperidine and 1,3,4-Oxadiazole as Multitargeted Therapeutics to Treat Alzheimer's Disease. ACS Chem Neurosci. 2019;10:4361-4384 pubmed publisher
Nuthakki V, Mudududdla R, Sharma A, Kumar A, Bharate S. Synthesis and biological evaluation of indoloquinoline alkaloid cryptolepine and its bromo-derivative as dual cholinesterase inhibitors. Bioorg Chem. 2019;90:103062 pubmed publisher
Zhao L, Zhao Y, Tang F, Xiong L, Su C, Mei L, et al. pHluorin-BACE1-mCherry Acts as a Reporter for the Intracellular Distribution of Active BACE1 In Vitro and In Vivo. Cells. 2019;8: pubmed publisher
Ali A, Abo El Ella D, El Emam S, Shahat A, El Sayed R. Physical & mental activities enhance the neuroprotective effect of vinpocetine & coenzyme Q10 combination against Alzheimer & bone remodeling in rats. Life Sci. 2019;229:21-35 pubmed publisher
Ali S, Asad M, Maity S, Zada W, Rizvanov A, Iqbal J, et al. Fluoro-benzimidazole derivatives to cure Alzheimer's disease: In-silico studies, synthesis, structure-activity relationship and in vivo evaluation for β secretase enzyme inhibition. Bioorg Chem. 2019;88:102936 pubmed publisher
Nuthakki V, Sharma A, Kumar A, Bharate S. Identification of embelin, a 3-undecyl-1,4-benzoquinone from Embelia ribes as a multitargeted anti-Alzheimer agent. Drug Dev Res. 2019;80:655-665 pubmed publisher
Sharma P, Tripathi A, Tripathi P, Prajapati S, Seth A, Tripathi M, et al. Design and development of multitarget-directed N-Benzylpiperidine analogs as potential candidates for the treatment of Alzheimer's disease. Eur J Med Chem. 2019;167:510-524 pubmed publisher
Marwarha G, Claycombe Larson K, Lund J, Schommer J, Ghribi O. A Diet Enriched in Palmitate and Deficient in Linoleate Exacerbates Oxidative Stress and Amyloid-β Burden in the Hippocampus of 3xTg-AD Mouse Model of Alzheimer's Disease. J Alzheimers Dis. 2019;68:219-237 pubmed publisher
Gutierrez L, Parravicini O, Sánchez E, Rodríguez R, Cobo J, Enriz R. New substituted aminopyrimidine derivatives as BACE1 inhibitors: in silico design, synthesis and biological assays. J Biomol Struct Dyn. 2019;37:229-246 pubmed publisher
Marwarha G, Claycombe Larson K, Lund J, Ghribi O. Palmitate-Induced SREBP1 Expression and Activation Underlies the Increased BACE 1 Activity and Amyloid Beta Genesis. Mol Neurobiol. 2018;: pubmed publisher
Qi C, Gao W, Wang J, Liu M, Zhang J, Chen C, et al. Terrusnolides A-D, new butenolides with anti-inflammatory activities from an endophytic Aspergillus from Tripterygium wilfordii. Fitoterapia. 2018;130:134-139 pubmed publisher
Gupta S, Yadav K, Mantri S, Singhal N, Ganesh S, Sandhir R. Evidence for Compromised Insulin Signaling and Neuronal Vulnerability in Experimental Model of Sporadic Alzheimer's Disease. Mol Neurobiol. 2018;55:8916-8935 pubmed publisher
Wilson E, Do Carmo S, Iulita M, Hall H, Ducatenzeiler A, Marks A, et al. BACE1 inhibition by microdose lithium formulation NP03 rescues memory loss and early stage amyloid neuropathology. Transl Psychiatry. 2017;7:e1190 pubmed publisher
Gutierrez L, Angelina E, Gyebrovszki A, Fülöp L, Peruchena N, Baldoni H, et al. New small-size peptides modulators of the exosite of BACE1 obtained from a structure-based design. J Biomol Struct Dyn. 2017;35:413-426 pubmed publisher
Hong L, Turner R, Koelsch G, Ghosh A, Tang J. Memapsin 2 (beta-secretase) as a therapeutic target. Biochem Soc Trans. 2002;30:530-4 pubmed
product information
Catalog Number :
CS0010
Product Name :
β-Secretase (BACE1) Activity Detection Kit (Fluorescent)
Product Type :
Molecular Platforms
Product Group :
Molecular Platforms
Product Description :
1 kit sufficient for 250 reactions
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA