This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Cholesterol Oxidase from Streptomyces sp.
catalog :
C8649
citations: 51
Reference
Xu S, Bala S, Bendeck M. Discoidin domain receptor 1 deficiency in vascular smooth muscle cells leads to mislocalisation of N-cadherin contacts. Biol Open. 2019;8: pubmed publisher
Ghosh S, Ahmad R, Khare S. Refolding of thermally denatured cholesterol oxidases by magnetic nanoparticles. Int J Biol Macromol. 2019;138:958-965 pubmed publisher
de la Roche M, Hamilton C, Mortensen R, Jeyaprakash A, Ghosh S, Anand P. Trafficking of cholesterol to the ER is required for NLRP3 inflammasome activation. J Cell Biol. 2018;217:3560-3576 pubmed publisher
Mukherjee P, Hough G, Chattopadhyay A, Navab M, Fogelman H, Meriwether D, et al. Transgenic tomatoes expressing the 6F peptide and ezetimibe prevent diet-induced increases of IFN-β and cholesterol 25-hydroxylase in jejunum. J Lipid Res. 2017;58:1636-1647 pubmed publisher
Brameshuber M, Sevcsik E, Rossboth B, Manner C, Deigner H, Peksel B, et al. Oxidized Phospholipids Inhibit the Formation of Cholesterol-Dependent Plasma Membrane Nanoplatforms. Biophys J. 2016;110:205-13 pubmed publisher
Cuddy L, Winick Ng W, Rylett R. Regulation of the high-affinity choline transporter activity and trafficking by its association with cholesterol-rich lipid rafts. J Neurochem. 2014;128:725-40 pubmed publisher
Fernández de Las Heras L, Perera J, Navarro Llorens J. Cholesterol to cholestenone oxidation by ChoG, the main extracellular cholesterol oxidase of Rhodococcus ruber strain Chol-4. J Steroid Biochem Mol Biol. 2014;139:33-44 pubmed publisher
Stępień A, Gonchar M. A simple method for the determination of the cholesterol esterase activity. Acta Biochim Pol. 2013;60:401-3 pubmed
Lange Y, Tabei S, Ye J, Steck T. Stability and stoichiometry of bilayer phospholipid-cholesterol complexes: relationship to cellular sterol distribution and homeostasis. Biochemistry. 2013;52:6950-9 pubmed publisher
Silva R, Carmona Ribeiro A, Petri D. Enzymatic activity of cholesterol oxidase immobilized onto polymer nanoparticles mediated by Congo red. Colloids Surf B Biointerfaces. 2013;110:347-55 pubmed publisher
Yang H, Chen Y, Xin Y, Zhang L, Zhang Y, Wang W. Chemically modified Sepharose as support for the immobilization of cholesterol oxidase. J Microbiol Biotechnol. 2013;23:1212-20 pubmed
Niwas R, Singh V, Singh R, Tripathi D, Tripathi C. Production, purification and characterization of cholesterol oxidase from a newly isolated Streptomyces sp. World J Microbiol Biotechnol. 2013;29:2077-85 pubmed publisher
Petrov A, Kasimov M, Giniatullin A, Zefirov A. [Membrane cholesterol oxidation effects on synaptic vesicle cycle in frog (RANA ridibunda) motor nerve terminals]. Ross Fiziol Zh Im I M Sechenova. 2013;99:245-60 pubmed
Faletrov Y, Bialevich K, Edimecheva I, Kostsin D, Rudaya E, Slobozhanina E, et al. 22-NBD-cholesterol as a novel fluorescent substrate for cholesterol-converting oxidoreductases. J Steroid Biochem Mol Biol. 2013;134:59-66 pubmed publisher
Brzostek A, Rumijowska Galewicz A, Dziadek B, Wojcik E, Dziadek J. ChoD and HsdD can be dispensable for cholesterol degradation in mycobacteria. J Steroid Biochem Mol Biol. 2013;134:1-7 pubmed publisher
Zhang H, Liu R, Zheng J. Selective determination of cholesterol based on cholesterol oxidase-alkaline phosphatase bienzyme electrode. Analyst. 2012;137:5363-7 pubmed publisher
Pessolano L, Sullivan C, Seidl S, Rich C, Liscum L, Stone P, et al. Trafficking of endogenous smooth muscle cell cholesterol: a role for serum amyloid A and interleukin-1β. Arterioscler Thromb Vasc Biol. 2012;32:2741-50 pubmed publisher
Manjunatha R, Shivappa Suresh G, Melo J, D Souza S, Venkatesha T. An amperometric bienzymatic cholesterol biosensor based on functionalized graphene modified electrode and its electrocatalytic activity towards total cholesterol determination. Talanta. 2012;99:302-9 pubmed publisher
Türkcan S, Masson J, Casanova D, Mialon G, Gacoin T, Boilot J, et al. Observing the confinement potential of bacterial pore-forming toxin receptors inside rafts with nonblinking Eu(3+)-doped oxide nanoparticles. Biophys J. 2012;102:2299-308 pubmed publisher
Wang C, Tan X, Chen S, Yuan R, Hu F, Yuan D, et al. Highly-sensitive cholesterol biosensor based on platinum-gold hybrid functionalized ZnO nanorods. Talanta. 2012;94:263-70 pubmed publisher
Viswanathan S, Li P, Choi W, Filipek S, Balasubramaniam T, Renugopalakrishnan V. Protein-carbon nanotube sensors: single platform integrated micro clinical lab for monitoring blood analytes. Methods Enzymol. 2012;509:165-94 pubmed publisher
Li R, Xiong C, Xiao Z, Ling L. Colorimetric detection of cholesterol with G-quadruplex-based DNAzymes and ABTS2-. Anal Chim Acta. 2012;724:80-5 pubmed publisher
Mathieu J, Wang F, Segatori L, Alvarez P. Increased resistance to oxysterol cytotoxicity in fibroblasts transfected with a lysosomally targeted Chromobacterium oxidase. Biotechnol Bioeng. 2012;109:2409-15 pubmed publisher
Mercer A, Szalewski R, Jackman S, Van Hook M, Thoreson W. Regulation of presynaptic strength by controlling Ca2+ channel mobility: effects of cholesterol depletion on release at the cone ribbon synapse. J Neurophysiol. 2012;107:3468-78 pubmed publisher
Nogovitsina E, Grishko V, Ivshina I. [Biocatalytic synthesis of pharmacology perspective stigmast-4-en-3-one using Rhodococci cells]. Bioorg Khim. 2011;37:697-704 pubmed
Lange Y, Ye J, Steck T. Activation mobilizes the cholesterol in the late endosomes-lysosomes of Niemann Pick type C cells. PLoS ONE. 2012;7:e30051 pubmed publisher
Wiegand V, Gimpl G. Specification of the cholesterol interaction with the oxytocin receptor using a chimeric receptor approach. Eur J Pharmacol. 2012;676:12-9 pubmed publisher
Ivashina T, Nikolayeva V, Dovbnya D, Donova M. Cholesterol oxidase ChoD is not a critical enzyme accounting for oxidation of sterols to 3-keto-4-ene steroids in fast-growing Mycobacterium sp. VKM Ac-1815D. J Steroid Biochem Mol Biol. 2012;129:47-53 pubmed publisher
Marques M, Fernandes P, Cabral J, Znidarsic Plazl P, Plazl I. Continuous steroid biotransformations in microchannel reactors. N Biotechnol. 2012;29:227-34 pubmed publisher
Yoshimoto F, Desilets M, Auchus R. Synthesis of halogenated pregnanes, mechanistic probes of steroid hydroxylases CYP17A1 and CYP21A2. J Steroid Biochem Mol Biol. 2012;128:38-50 pubmed publisher
Wicklein B, Darder M, Aranda P, Ruiz Hitzky E. Phospholipid-sepiolite biomimetic interfaces for the immobilization of enzymes. ACS Appl Mater Interfaces. 2011;3:4339-48 pubmed publisher
Xin Y, Yang H, Xiao X, Zhang L, Zhang Y, Tong Y, et al. Preparation and characterization of affinity sorbents based on isoalloxazine-like ligands for separation of flavoenzymes. J Sep Sci. 2011;34:2940-9 pubmed publisher
Praveen V, Srivastava A, Tripathi C. Purification and characterization of the enzyme cholesterol oxidase from a new isolate of Streptomyces sp. Appl Biochem Biotechnol. 2011;165:1414-26 pubmed publisher
Eguílaz M, Villalonga R, Yáñez Sedeño P, Pingarron J. Designing electrochemical interfaces with functionalized magnetic nanoparticles and wrapped carbon nanotubes as platforms for the construction of high-performance bienzyme biosensors. Anal Chem. 2011;83:7807-14 pubmed publisher
Ahire J, Bhat A, Thakare J, Pawar P, Zope D, Jain R, et al. Cholesterol assimilation and biotransformation by Lactobacillus helveticus. Biotechnol Lett. 2012;34:103-7 pubmed publisher
Manzano J, Carvalho L, García Hernández R, Poveda J, Ferragut J, Castanys S, et al. Uptake of the antileishmania drug tafenoquine follows a sterol-dependent diffusion process in Leishmania. J Antimicrob Chemother. 2011;66:2562-5 pubmed publisher
Sun Y, Yang H, Wang W. Improvement of the thermostability and enzymatic activity of cholesterol oxidase by site-directed mutagenesis. Biotechnol Lett. 2011;33:2049-55 pubmed publisher
Brameshuber M, Weghuber J, Ruprecht V, Gombos I, Horvath I, Vigh L, et al. Imaging of mobile long-lived nanoplatforms in the live cell plasma membrane. J Biol Chem. 2010;285:41765-71 pubmed publisher
Vrielink A. Cholesterol oxidase: structure and function. Subcell Biochem. 2010;51:137-58 pubmed publisher
Caldinelli L, Iametti S, Barbiroli A, Bonomi F, Fessas D, Molla G, et al. Dissecting the structural determinants of the stability of cholesterol oxidase containing covalently bound flavin. J Biol Chem. 2005;280:22572-81 pubmed
Ahn K, Sampson N. Cholesterol oxidase senses subtle changes in lipid bilayer structure. Biochemistry. 2004;43:827-36 pubmed
Lolekha P, Srisawasdi P, Jearanaikoon P, Wetprasit N, Sriwanthana B, Kroll M. Performance of four sources of cholesterol oxidase for serum cholesterol determination by the enzymatic endpoint method. Clin Chim Acta. 2004;339:135-45 pubmed
Stadtman T, CHERKES A, Anfinsen C. Studies on the microbiological degradation of cholesterol. J Biol Chem. 1954;206:511-23 pubmed
Toyama M, Yamashita M, Yoneda M, Zaborowski A, Nagato M, Ono H, et al. Alteration of substrate specificity of cholesterol oxidase from Streptomyces sp. by site-directed mutagenesis. Protein Eng. 2002;15:477-84 pubmed
Corbin D, Grebenok R, Ohnmeiss T, Greenplate J, Purcell J. Expression and chloroplast targeting of cholesterol oxidase in transgenic tobacco plants. Plant Physiol. 2001;126:1116-28 pubmed
Maclachlan J, Wotherspoon A, Ansell R, Brooks C. Cholesterol oxidase: sources, physical properties and analytical applications. J Steroid Biochem Mol Biol. 2000;72:169-95 pubmed
Uematsu S, Uchida T, Kinoshita A, Kimura F, Akahori Y. Relation between micellar structure of model bile and activity of esterase. Biochim Biophys Acta. 1995;1258:122-34 pubmed
Pal R, Barenholz Y, Wagner R. Effect of cholesterol concentration on organization of viral and vesicle membranes. Probed by accessibility to cholesterol oxidase. J Biol Chem. 1980;255:5802-6 pubmed
Allain C, Poon L, Chan C, Richmond W, Fu P. Enzymatic determination of total serum cholesterol. Clin Chem. 1974;20:470-5 pubmed
Richmond W. Preparation and properties of a cholesterol oxidase from Nocardia sp. and its application to the enzymatic assay of total cholesterol in serum. Clin Chem. 1973;19:1350-6 pubmed
Slotte J, Hedström G, Rannström S, Ekman S. Effects of sphingomyelin degradation on cell cholesterol oxidizability and steady-state distribution between the cell surface and the cell interior. Biochim Biophys Acta. 1989;985:90-6 pubmed
product information
Catalog Number :
C8649
Product Name :
Cholesterol Oxidase from Streptomyces sp.
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
lyophilized powder, ?20 units/mg protein
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA