product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-Cytokeratin Peptide 18 antibody produced in mouse
catalog :
C8541
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CY-90
reactivity :
human, bovine, domestic rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 20
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 1b
Mathieu A, Ohl Séguy E, Dubois M, Jean D, Jones C, Boudreau F, et al. Subcellular proteomics analysis of different stages of colorectal cancer cell lines. Proteomics. 2016;16:3009-3018 pubmed publisher
  • immunoprecipitation; human; fig 3
  • western blot; human; fig 1
Kakade P, Budnar S, Kalraiya R, Vaidya M. Functional Implications of O-GlcNAcylation-dependent Phosphorylation at a Proximal Site on Keratin 18. J Biol Chem. 2016;291:12003-13 pubmed publisher
  • flow cytometry; human; 1:100; loading ...; fig 2a
  • immunohistochemistry; human; 1:100; loading ...; fig 1
Trisdale S, Schwab N, Hou X, Davis J, Townson D. Molecular manipulation of keratin 8/18 intermediate filaments: modulators of FAS-mediated death signaling in human ovarian granulosa tumor cells. J Ovarian Res. 2016;9:8 pubmed publisher
  • immunocytochemistry; human; fig S1
Yang P, Baciu P, Kerrigan B, Etheridge M, Sung E, Toimil B, et al. Retinal pigment epithelial cell death by the alternative complement cascade: role of membrane regulatory proteins, calcium, PKC, and oxidative stress. Invest Ophthalmol Vis Sci. 2014;55:3012-21 pubmed publisher
  • immunohistochemistry - paraffin section; domestic rabbit; 1:100
Liu Z, Yu N, Holz F, Yang F, Stanzel B. Enhancement of retinal pigment epithelial culture characteristics and subretinal space tolerance of scaffolds with 200 nm fiber topography. Biomaterials. 2014;35:2837-50 pubmed publisher
  • immunocytochemistry; bovine; 1:800
Duncan A, Forcina J, Birt A, Townson D. Estrous cycle-dependent changes of Fas expression in the bovine corpus luteum: influence of keratin 8/18 intermediate filaments and cytokines. Reprod Biol Endocrinol. 2012;10:90 pubmed publisher
Ibraheem K, Yhmed A, Qayyum T, Bryan N, Georgopoulos N. CD40 induces renal cell carcinoma-specific differential regulation of TRAF proteins, ASK1 activation and JNK/p38-mediated, ROS-dependent mitochondrial apoptosis. Cell Death Discov. 2019;5:148 pubmed publisher
Kolundžić N, Khurana P, Devito L, Jeriha J, Marx J, Hobbs C, et al. Induced pluripotent stem cell line heterozygous for p.R501X mutation in filaggrin: KCLi003-A. Stem Cell Res. 2019;39:101527 pubmed publisher
Loch C, Haeger J, Pfarrer C. IFNτ mediates chemotaxis, motility, metabolism and CK18 downregulation in bovine trophoblast cells in vitro via STAT1 and MAPK42/44 signaling. Placenta. 2018;64:17-26 pubmed publisher
Nishikawa N, Kanematsu A, Negoro H, Imamura M, Sugino Y, Okinami T, et al. PTHrP is endogenous relaxant for spontaneous smooth muscle contraction in urinary bladder of female rat. Endocrinology. 2013;154:2058-68 pubmed publisher
Nunez Parra A, Cortés Campos C, Bacigalupo J, García M, Nualart F, Reyes J. Expression and distribution of facilitative glucose (GLUTs) and monocarboxylate/H+ (MCTs) transporters in rat olfactory epithelia. Chem Senses. 2011;36:771-80 pubmed publisher
Meyerholz D, Stoltz D, Namati E, Ramachandran S, Pezzulo A, Smith A, et al. Loss of cystic fibrosis transmembrane conductance regulator function produces abnormalities in tracheal development in neonatal pigs and young children. Am J Respir Crit Care Med. 2010;182:1251-61 pubmed publisher
Ahenkorah J, Hottor B, Byrne S, Bosio P, Ockleford C. Immunofluorescence confocal laser scanning microscopy and immuno-electron microscopic identification of keratins in human materno-foetal interaction zone. J Cell Mol Med. 2009;13:735-48 pubmed publisher
Li H, Zhou J, Miki J, Furusato B, Gu Y, Srivastava S, et al. Telomerase-immortalized non-malignant human prostate epithelial cells retain the properties of multipotent stem cells. Exp Cell Res. 2008;314:92-102 pubmed
Blomberg L, Garrett W, Guillomot M, Miles J, Sonstegard T, van Tassell C, et al. Transcriptome profiling of the tubular porcine conceptus identifies the differential regulation of growth and developmentally associated genes. Mol Reprod Dev. 2006;73:1491-502 pubmed
Brabletz T, Spaderna S, Kolb J, Hlubek F, Faller G, Bruns C, et al. Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: an active role for the tumor environment in malignant tumor progression. Cancer Res. 2004;64:6973-7 pubmed
You H, Yu W, Munoz Medellin D, Brown P, Sanders B, Kline K. Role of extracellular signal-regulated kinase pathway in RRR-alpha-tocopheryl succinate-induced differentiation of human MDA-MB-435 breast cancer cells. Mol Carcinog. 2002;33:228-36 pubmed
Inada H, Izawa I, Nishizawa M, Fujita E, Kiyono T, Takahashi T, et al. Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD. J Cell Biol. 2001;155:415-26 pubmed
Offord E, Sharif N, Mace K, Tromvoukis Y, Spillare E, Avanti O, et al. Immortalized human corneal epithelial cells for ocular toxicity and inflammation studies. Invest Ophthalmol Vis Sci. 1999;40:1091-101 pubmed
Hasan A, Zisman T, Schmaier A. Identification of cytokeratin 1 as a binding protein and presentation receptor for kininogens on endothelial cells. Proc Natl Acad Sci U S A. 1998;95:3615-20 pubmed
product information
Product No. :
C8541
Product Name :
Monoclonal Anti-Cytokeratin Peptide 18 antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
CY-90
Applications/Description :
Suitable for indirect immunofluorescence: 1:800 using formalin-fixed, paraffin-embedded sections of human tissue; western blot
Species Reactivity :
wide range
Isotype :
IgG1
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA