product summary
company name :
MilliporeSigma
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
product type :
antibody
product name :
Anti-Calcitonin Gene Related Peptide antibody produced in rabbit
catalog :
C8198
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, dot blot
more info or order :
citations: 64
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig 2c
Niiro A, Ohno S, Yamagata K, Yamagata K, Tomita K, Kuramoto E, et al. Diurnal Variation in Trigeminal Pain Sensitivity in Mice. Front Neurosci. 2021;15:703440 pubmed publisher
  • immunohistochemistry; mouse; 1:10,000; loading ...; fig 4a
Gutierrez S, Eisenach J, Boada M. Seeding of breast cancer cell line (MDA-MB-231LUC+) to the mandible induces overexpression of substance P and CGRP throughout the trigeminal ganglion and widespread peripheral sensory neuropathy throughout all three of its divisions. Mol Pain. 2021;17:17448069211024082 pubmed publisher
  • immunohistochemistry; mouse; 1:250; loading ...; fig 1c
Olsen R, Ireland A, Kastner D, Groves S, Spainhower K, Pozo K, et al. ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer. Genes Dev. 2021;35:847-869 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 7a
Lin T, Quellier D, Lamb J, Voisin T, Baral P, Bock F, et al. Pseudomonas aeruginosa-induced nociceptor activation increases susceptibility to infection. PLoS Pathog. 2021;17:e1009557 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 4k
Meyers C, Lee S, Sono T, Xu J, Negri S, Tian Y, et al. A Neurotrophic Mechanism Directs Sensory Nerve Transit in Cranial Bone. Cell Rep. 2020;31:107696 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:2000; loading ...; fig 1d
Lorenzo L, Godin A, Ferrini F, Bachand K, Plasencia Fernandez I, Labrecque S, et al. Enhancing neuronal chloride extrusion rescues α2/α3 GABAA-mediated analgesia in neuropathic pain. Nat Commun. 2020;11:869 pubmed publisher
  • immunohistochemistry; mouse; 1:5000; loading ...; fig 1b
Hockley J, Barker K, Taylor T, Callejo G, Husson Z, Bulmer D, et al. Acid and inflammatory sensitisation of naked mole-rat colonic afferent nerves. Mol Pain. 2020;16:1744806920903150 pubmed publisher
  • immunohistochemistry; mouse; 1:10,000; loading ...; fig 1s2a
Smith K, Browne T, Davis O, Coyle A, Boyle K, Watanabe M, et al. Calretinin positive neurons form an excitatory amplifier network in the spinal cord dorsal horn. elife. 2019;8: pubmed publisher
  • immunohistochemistry; mouse; 1:2500; loading ...; fig 3b
Stupnikov M, Yang Y, Mori M, LU J, Cardoso W. Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation. elife. 2019;8: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:800; loading ...; fig 1a
Khoutorsky A, Sorge R, Prager Khoutorsky M, Pawlowski S, Longo G, Jafarnejad S, et al. eIF2? phosphorylation controls thermal nociception. Proc Natl Acad Sci U S A. 2016;113:11949-11954 pubmed
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 6e'
Borromeo M, Savage T, Kollipara R, He M, Augustyn A, Osborne J, et al. ASCL1 and NEUROD1 Reveal Heterogeneity in Pulmonary Neuroendocrine Tumors and Regulate Distinct Genetic Programs. Cell Rep. 2016;16:1259-1272 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:6000; fig 3
Antony N, McDougall A, Mantamadiotis T, Cole T, Bird A. Creb1 regulates late stage mammalian lung development via respiratory epithelial and mesenchymal-independent mechanisms. Sci Rep. 2016;6:25569 pubmed publisher
Gras S, Blasco A, Mòdol Caballero G, Tarabal O, Casanovas A, Piedrafita L, et al. Beneficial effects of dietary supplementation with green tea catechins and cocoa flavanols on aging-related regressive changes in the mouse neuromuscular system. Aging (Albany NY). 2021;13:18051-18093 pubmed publisher
Guan S, Zhang K, Wang X, Yang L, Feng B, Tian D, et al. Anxiolytic effects of polydatin through the blockade of neuroinflammation in a chronic pain mouse model. Mol Pain. 2020;16:1744806919900717 pubmed publisher
Ng S, Rideout W, Akama Garren E, Bhutkar A, Mercer K, Schenkel J, et al. CRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancer. Proc Natl Acad Sci U S A. 2019;: pubmed publisher
Mori M, Furuhashi K, Danielsson J, Hirata Y, Kakiuchi M, Lin C, et al. Generation of functional lungs via conditional blastocyst complementation using pluripotent stem cells. Nat Med. 2019;25:1691-1698 pubmed publisher
Berger J, Singh P, Khrimian L, Morgan D, Chowdhury S, Arteaga Solis E, et al. Mediation of the Acute Stress Response by the Skeleton. Cell Metab. 2019;30:890-902.e8 pubmed publisher
Katiyar K, Struzyna L, Das S, Cullen D. Stretch growth of motor axons in custom mechanobioreactors to generate long-projecting axonal constructs. J Tissue Eng Regen Med. 2019;13:2040-2054 pubmed publisher
Okada S, Saito H, Matsuura Y, Mikuzuki L, Sugawara S, Onose H, et al. Upregulation of calcitonin gene-related peptide, neuronal nitric oxide synthase, and phosphorylated extracellular signal-regulated kinase 1/2 in the trigeminal ganglion after bright light stimulation of the eye in rats. J Oral Sci. 2019;61:146-155 pubmed publisher
Liu Q, Liu K, Cui G, Huang X, Yao S, Guo W, et al. Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction. Nat Genet. 2019;51:728-738 pubmed publisher
Bautzová T, Hockley J, Pérez Berezo T, Pujo J, Tranter M, Desormeaux C, et al. 5-oxoETE triggers nociception in constipation-predominant irritable bowel syndrome through MAS-related G protein-coupled receptor D. Sci Signal. 2018;11: pubmed publisher
Cai W, Zhao Q, Shao J, Zhang J, Li L, Ren X, et al. MicroRNA-182 Alleviates Neuropathic Pain by Regulating Nav1.7 Following Spared Nerve Injury in Rats. Sci Rep. 2018;8:16750 pubmed publisher
Squair J, Ruiz I, Phillips A, Zheng M, Sarafis Z, Sachdeva R, et al. Minocycline Reduces the Severity of Autonomic Dysreflexia after Experimental Spinal Cord Injury. J Neurotrauma. 2018;35:2861-2871 pubmed publisher
van der Heijden M, Zoghbi H. Loss of Atoh1 from neurons regulating hypoxic and hypercapnic chemoresponses causes neonatal respiratory failure in mice. elife. 2018;7: pubmed publisher
Cowie A, Moehring F, O Hara C, Stucky C. Optogenetic Inhibition of CGRPα Sensory Neurons Reveals Their Distinct Roles in Neuropathic and Incisional Pain. J Neurosci. 2018;38:5807-5825 pubmed publisher
Patil M, Hovhannisyan A, Akopian A. Characteristics of sensory neuronal groups in CGRP-cre-ER reporter mice: Comparison to Nav1.8-cre, TRPV1-cre and TRPV1-GFP mouse lines. PLoS ONE. 2018;13:e0198601 pubmed publisher
Cerveró C, Blasco A, Tarabal O, Casanovas A, Piedrafita L, Navarro X, et al. Glial Activation and Central Synapse Loss, but Not Motoneuron Degeneration, Are Prevented by the Sigma-1 Receptor Agonist PRE-084 in the Smn2B/- Mouse Model of Spinal Muscular Atrophy. J Neuropathol Exp Neurol. 2018;77:577-597 pubmed publisher
Nencini S, Ringuet M, Kim D, Greenhill C, Ivanusic J. GDNF, Neurturin, and Artemin Activate and Sensitize Bone Afferent Neurons and Contribute to Inflammatory Bone Pain. J Neurosci. 2018;38:4899-4911 pubmed publisher
Baral P, Umans B, Li L, Wallrapp A, Bist M, Kirschbaum T, et al. Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia. Nat Med. 2018;24:417-426 pubmed publisher
Ritter K, Wang Z, Vezina C, Bjorling D, Southard Smith E. Serotonin Receptor 5-HT3A Affects Development of Bladder Innervation and Urinary Bladder Function. Front Neurosci. 2017;11:690 pubmed publisher
Park S, Eber M, Tsuzuki S, Booker M, Sunil A, Widner D, et al. Adeno-associated virus serotype rh10 is a useful gene transfer vector for sensory nerves that innervate bone in immunodeficient mice. Sci Rep. 2017;7:17428 pubmed publisher
Kim J, Ahn M, Choi Y, Hyeon J, Shin T. Immunohistochemical study of arginases 1 and 2 in the olfactory bulbs of the Korean roe deer, Capreolus pygargus. Acta Histochem. 2017;119:696-700 pubmed publisher
Akeno N, Reece A, Callahan M, Miller A, Kim R, He D, et al. TRP53 Mutants Drive Neuroendocrine Lung Cancer Through Loss-of-Function Mechanisms with Gain-of-Function Effects on Chemotherapy Response. Mol Cancer Ther. 2017;16:2913-2926 pubmed publisher
Mikuzuki L, Saito H, Katagiri A, Okada S, Sugawara S, Kubo A, et al. Phenotypic change in trigeminal ganglion neurons associated with satellite cell activation via extracellular signal-regulated kinase phosphorylation is involved in lingual neuropathic pain. Eur J Neurosci. 2017;46:2190-2202 pubmed publisher
Beaudry H, Daou I, Ase A, Ribeiro Da Silva A, Séguéla P. Distinct behavioral responses evoked by selective optogenetic stimulation of the major TRPV1+ and MrgD+ subsets of C-fibers. Pain. 2017;158:2329-2339 pubmed publisher
Sidorova Y, Bespalov M, Wong A, Kambur O, Jokinen V, Lilius T, et al. A Novel Small Molecule GDNF Receptor RET Agonist, BT13, Promotes Neurite Growth from Sensory Neurons in Vitro and Attenuates Experimental Neuropathy in the Rat. Front Pharmacol. 2017;8:365 pubmed publisher
Nishijima H, Kondo K, Toma Hirano M, Kikuta S, Ando M, Ueha R, et al. Prolonged denervation induces remodeling of nasal mucosa in rat model of posterior nasal neurectomy. Int Forum Allergy Rhinol. 2017;7:670-678 pubmed publisher
Lim J, Ibaseta A, Fischer M, Cancilla B, O Young G, Cristea S, et al. Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer. Nature. 2017;545:360-364 pubmed publisher
Bernal Sierra Y, Haseleu J, Kozlenkov A, Begay V, Lewin G. Genetic Tracing of Cav3.2 T-Type Calcium Channel Expression in the Peripheral Nervous System. Front Mol Neurosci. 2017;10:70 pubmed publisher
Otsubo K, Goto H, Nishio M, Kawamura K, Yanagi S, Nishie W, et al. MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion and tumour formation. Oncogene. 2017;36:4201-4211 pubmed publisher
Song H, Lin C, Yao E, Zhang K, Li X, Wu Q, et al. Selective Ablation of Tumor Suppressors in Parafollicular C Cells Elicits Medullary Thyroid Carcinoma. J Biol Chem. 2017;292:3888-3899 pubmed publisher
Ritter K, Southard Smith E. Dynamic Expression of Serotonin Receptor 5-HT3A in Developing Sensory Innervation of the Lower Urinary Tract. Front Neurosci. 2016;10:592 pubmed publisher
Moutal A, Eyde N, Telemi E, Park K, Xie J, Dodick D, et al. Efficacy of (S)-Lacosamide in preclinical models of cephalic pain. Pain Rep. 2016;1: pubmed
Shao J, Cao J, Wang J, Ren X, Su S, Li M, et al. MicroRNA-30b regulates expression of the sodium channel Nav1.7 in nerve injury-induced neuropathic pain in the rat. Mol Pain. 2016;12: pubmed
Wu N, Jia D, Ibrahim A, Bachurski C, Gronostajski R, MacPherson D. NFIB overexpression cooperates with Rb/p53 deletion to promote small cell lung cancer. Oncotarget. 2016;7:57514-57524 pubmed publisher
Iyer S, Vesuna S, Ramakrishnan C, Huynh K, Young S, Berndt A, et al. Optogenetic and chemogenetic strategies for sustained inhibition of pain. Sci Rep. 2016;6:30570 pubmed publisher
Lieu T, Savage E, Zhao P, Edgington Mitchell L, Barlow N, Bron R, et al. Antagonism of the proinflammatory and pronociceptive actions of canonical and biased agonists of protease-activated receptor-2. Br J Pharmacol. 2016;173:2752-65 pubmed publisher
Nishijima H, Kondo K, Toma Hirano M, Iwasaki S, Kikuta S, Fujimoto C, et al. Denervation of nasal mucosa induced by posterior nasal neurectomy suppresses nasal secretion, not hypersensitivity, in an allergic rhinitis rat model. Lab Invest. 2016;96:981-93 pubmed publisher
Katiyar K, Winter C, Struzyna L, Harris J, Cullen D. Mechanical elongation of astrocyte processes to create living scaffolds for nervous system regeneration. J Tissue Eng Regen Med. 2017;11:2737-2751 pubmed publisher
da Silva Serra I, Husson Z, Bartlett J, Smith E. Characterization of cutaneous and articular sensory neurons. Mol Pain. 2016;12: pubmed publisher
Bonin R, Wang F, Desrochers Couture M, Ga Secka A, Boulanger M, Côté D, et al. Epidural optogenetics for controlled analgesia. Mol Pain. 2016;12: pubmed publisher
Sugimura Y, Takahashi Y, Watabe A, Kato F. Synaptic and network consequences of monosynaptic nociceptive inputs of parabrachial nucleus origin in the central amygdala. J Neurophysiol. 2016;115:2721-39 pubmed publisher
Gorin C, Rochefort G, Bascetin R, Ying H, Lesieur J, Sadoine J, et al. Priming Dental Pulp Stem Cells With Fibroblast Growth Factor-2 Increases Angiogenesis of Implanted Tissue-Engineered Constructs Through Hepatocyte Growth Factor and Vascular Endothelial Growth Factor Secretion. Stem Cells Transl Med. 2016;5:392-404 pubmed publisher
Lin S, Barrette A, Chapin C, Gonzales L, Gonzalez R, Dobbs L, et al. Expression of human carcinoembryonic antigen-related cell adhesion molecule 6 and alveolar progenitor cells in normal and injured lungs of transgenic mice. Physiol Rep. 2015;3: pubmed publisher
Khoutorsky A, Bonin R, Sorge R, Gkogkas C, Pawlowski S, Jafarnejad S, et al. Translational control of nociception via 4E-binding protein 1. elife. 2015;4: pubmed publisher
Cerveró C, Montull N, Tarabal O, Piedrafita L, Esquerda J, Calderó J. Chronic Treatment with the AMPK Agonist AICAR Prevents Skeletal Muscle Pathology but Fails to Improve Clinical Outcome in a Mouse Model of Severe Spinal Muscular Atrophy. Neurotherapeutics. 2016;13:198-216 pubmed publisher
Mauprivez C, Bataille C, Baroukh B, Llorens A, Lesieur J, Marie P, et al. Periosteum Metabolism and Nerve Fiber Positioning Depend on Interactions between Osteoblasts and Peripheral Innervation in Rat Mandible. PLoS ONE. 2015;10:e0140848 pubmed publisher
Struzyna L, Wolf J, Mietus C, Adewole D, Chen H, Smith D, et al. Rebuilding Brain Circuitry with Living Micro-Tissue Engineered Neural Networks. Tissue Eng Part A. 2015;21:2744-56 pubmed publisher
Saeed A, Pawlowski S, Ribeiro Da Silva A. Limited changes in spinal lamina I dorsal horn neurons following the cytotoxic ablation of non-peptidergic C-fibers. Mol Pain. 2015;11:54 pubmed publisher
Avetisyan M, Wang H, Schill E, Bery S, Grider J, Hassell J, et al. Hepatocyte Growth Factor and MET Support Mouse Enteric Nervous System Development, the Peristaltic Response, and Intestinal Epithelial Proliferation in Response to Injury. J Neurosci. 2015;35:11543-58 pubmed publisher
Alamri A, Bron R, Brock J, Ivanusic J. Transient receptor potential cation channel subfamily V member 1 expressing corneal sensory neurons can be subdivided into at least three subpopulations. Front Neuroanat. 2015;9:71 pubmed publisher
Asahara M, Ito N, Yokomizo T, Nakamura M, Shimizu T, Yamada Y. The absence of the leukotriene B4 receptor BLT1 attenuates peripheral inflammation and spinal nociceptive processing following intraplantar formalin injury. Mol Pain. 2015;11:11 pubmed publisher
McCarthy C, Tomasella E, Malet M, Seroogy K, Hökfelt T, Villar M, et al. Axotomy of tributaries of the pelvic and pudendal nerves induces changes in the neurochemistry of mouse dorsal root ganglion neurons and the spinal cord. Brain Struct Funct. 2016;221:1985-2004 pubmed publisher
Stenkamp Strahm C, Kappmeyer A, Schmalz J, Gericke M, Balemba O. High-fat diet ingestion correlates with neuropathy in the duodenum myenteric plexus of obese mice with symptoms of type 2 diabetes. Cell Tissue Res. 2013;354:381-94 pubmed publisher
product information
Product No. :
C8198
Product Name :
Anti-Calcitonin Gene Related Peptide antibody produced in rabbit
Host :
rabbit
Conjugate :
unconjugated
Antibody Type :
polyclonal
Applications/Description :
Suitable for ELISA; immunohistochemistry: 1:8,000 using 4% paraformaldehyde perfusion-fixed, frozen sections of rat brain; dot blot: 1:10,000
Species Reactivity :
rat
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA