Fu L, Wei C, Powell P, Bradley W, Ahmad S, Ferrario C, et al. Increased fibroblast chymase production mediates procollagen autophagic digestion in volume overload. J Mol Cell Cardiol. 2016;92:1-9 pubmed publisher

Lysvand H, Hagen L, Klubicka L, Slupphaug G, Iversen O. Psoriasis pathogenesis - Pso p27 is generated from SCCA1 with chymase. Biochim Biophys Acta. 2014;1842:734-8 pubmed publisher

Bankova L, Lezcano C, Pejler G, Stevens R, Murphy G, Austen K, et al. Mouse mast cell proteases 4 and 5 mediate epidermal injury through disruption of tight junctions. J Immunol. 2014;192:2812-20 pubmed publisher

Reber L, Daubeuf F, Pejler G, Abrink M, Frossard N. Mast cells contribute to bleomycin-induced lung inflammation and injury in mice through a chymase/mast cell protease 4-dependent mechanism. J Immunol. 2014;192:1847-54 pubmed publisher

Higashi N, Waki M, Sue M, Kogane Y, Shida H, Tsunekawa N, et al. Heparanase-mediated cleavage of macromolecular heparin accelerates release of granular components of mast cells from extracellular matrices. Biochem J. 2014;458:291-9 pubmed publisher

Roy A, Ganesh G, Sippola H, Bolin S, Sawesi O, Dagälv A, et al. Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin-33 (IL-33) and limits danger-induced inflammation. J Biol Chem. 2014;289:237-50 pubmed publisher

Matsumoto Y, Kakuda S, Koizumi M, Mizuno T, Muroga Y, Kawamura T, et al. Crystal structure of a complex of human chymase with its benzimidazole derived inhibitor. J Synchrotron Radiat. 2013;20:914-8 pubmed publisher

Ruffell B, Affara N, Cottone L, Junankar S, Johansson M, DeNardo D, et al. Cathepsin C is a tissue-specific regulator of squamous carcinogenesis. Genes Dev. 2013;27:2086-98 pubmed publisher

Wang Y, Alexander J. Role of chymase in preeclampsia. Curr Vasc Pharmacol. 2013;11:606-15 pubmed

Nakazawa S, Sakanaka M, Furuta K, Natsuhara M, Takano H, Tsuchiya S, et al. Histamine synthesis is required for granule maturation in murine mast cells. Eur J Immunol. 2014;44:204-14 pubmed publisher

El Hamarneh T, Hey Cunningham A, Berbic M, Al Jefout M, Fraser I, Black K. Cellular immune environment in endometrial polyps. Fertil Steril. 2013;100:1364-72 pubmed publisher

Moniwa N, Varagic J, Simington S, Ahmad S, Nagata S, VonCannon J, et al. Primacy of angiotensin converting enzyme in angiotensin-(1-12) metabolism. Am J Physiol Heart Circ Physiol. 2013;305:H644-50 pubmed publisher

de Haan J, Hadfoune M, Lubbers T, Hodin C, Lenaerts K, Ito A, et al. Lipid-rich enteral nutrition regulates mucosal mast cell activation via the vagal anti-inflammatory reflex. Am J Physiol Gastrointest Liver Physiol. 2013;305:G383-91 pubmed publisher

Białas M, Dyduch G, Szpor J, Demczuk S, Okon K. Microvascular density and mast cells in benign and malignant pheochromocytomas. Pol J Pathol. 2012;63:235-42 pubmed

Groschwitz K, Wu D, Osterfeld H, Ahrens R, Hogan S. Chymase-mediated intestinal epithelial permeability is regulated by a protease-activating receptor/matrix metalloproteinase-2-dependent mechanism. Am J Physiol Gastrointest Liver Physiol. 2013;304:G479-89 pubmed publisher

Jiang L, Hua Y, Shen Q, Ding S, Jiang W, Zhang W, et al. Role of mast cells in gynecological neoplasms. Front Biosci (Landmark Ed). 2013;18:773-81 pubmed

Waern I, Lundequist A, Pejler G, Wernersson S. Mast cell chymase modulates IL-33 levels and controls allergic sensitization in dust-mite induced airway inflammation. Mucosal Immunol. 2013;6:911-20 pubmed publisher

Anower E Khuda M, Habuchi H, Nagai N, Habuchi O, Yokochi T, Kimata K. Heparan sulfate 6-O-sulfotransferase isoform-dependent regulatory effects of heparin on the activities of various proteases in mast cells and the biosynthesis of 6-O-sulfated heparin. J Biol Chem. 2013;288:3705-17 pubmed publisher

Park S, Bivona B, Ford S, Xu S, Kobori H, de Garavilla L, et al. Direct evidence for intrarenal chymase-dependent angiotensin II formation on the diabetic renal microvasculature. Hypertension. 2013;61:465-71 pubmed publisher

Hendrix S, Kramer P, Pehl D, Warnke K, Boato F, Nelissen S, et al. Mast cells protect from post-traumatic brain inflammation by the mast cell-specific chymase mouse mast cell protease-4. FASEB J. 2013;27:920-9 pubmed publisher

Guhl S, Artuc M, Zuberbier T, Babina M. Testosterone exerts selective anti-inflammatory effects on human skin mast cells in a cell subset dependent manner. Exp Dermatol. 2012;21:878-80 pubmed publisher

Xue S, Yang W, Sun J. Role of chymotrypsin-like serine proteinase in white spot syndrome virus infection in Fenneropenaeus chinensis. Fish Shellfish Immunol. 2013;34:403-9 pubmed publisher

Yang C, Rupa P, Kanatani H, Nakamura A, Ibuki M, Mine Y. Prophylaxis of intranasally induced pollen allergy in a BALB/C mouse model using a potential prebiotic β-1, 4 mannobiose. Allergol Int. 2013;62:53-64 pubmed publisher

Thorpe M, Yu J, Boinapally V, Ahooghalandari P, Kervinen J, Garavilla L, et al. Extended cleavage specificity of the mast cell chymase from the crab-eating macaque (Macaca fascicularis): an interesting animal model for the analysis of the function of the human mast cell chymase. Int Immunol. 2012;24:771-82 pubmed publisher

Siltari A, Kivimäki A, Ehlers P, Korpela R, Vapaatalo H. Effects of milk casein derived tripeptides on endothelial enzymes in vitro; a study with synthetic tripeptides. Arzneimittelforschung. 2012;62:477-81 pubmed publisher

Oka T, Kalesnikoff J, Starkl P, Tsai M, Galli S. Evidence questioning cromolyn's effectiveness and selectivity as a 'mast cell stabilizer' in mice. Lab Invest. 2012;92:1472-82 pubmed publisher

Wang Y, Shi G. Mast cell chymase and tryptase in abdominal aortic aneurysm formation. Trends Cardiovasc Med. 2012;22:150-5 pubmed publisher

Piliponsky A, Chen C, Rios E, Treuting P, Lahiri A, Abrink M, et al. The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis. Am J Pathol. 2012;181:875-86 pubmed publisher

Afferson H, Eleftheriou E, Selkirk M, Gounaris K. Trichinella spiralis secreted enzymes regulate nucleotide-induced mast cell activation and release of mouse mast cell protease 1. Infect Immun. 2012;80:3761-7 pubmed publisher

Yang Y, Liu X, Huang J, Zhong Y, Mao Z, Xiao H, et al. Inhibition of p38 mitogen-activated protein kinase phosphorylation decrease tert-butyl hydroperoxide-induced apoptosis in human trabecular meshwork cells. Mol Vis. 2012;18:2127-36 pubmed

Cristovam P, Carmona A, Arnoni C, Maquigussa E, Pereira L, Boim M. Role of chymase in diabetic nephropathy. Exp Biol Med (Maywood). 2012;237:985-92 pubmed publisher

Nguyen S, Öörni K, Lee Rueckert M, Pihlajamaa T, Metso J, Jauhiainen M, et al. Spontaneous remodeling of HDL particles at acidic pH enhances their capacity to induce cholesterol efflux from human macrophage foam cells. J Lipid Res. 2012;53:2115-25 pubmed publisher

Li J, Lu H, Plante E, Melendez G, Levick S, Janicki J. Stem cell factor is responsible for the rapid response in mature mast cell density in the acutely stressed heart. J Mol Cell Cardiol. 2012;53:469-74 pubmed publisher

Gu Y, Groome L, Alexander J, Wang Y. PAR-2 triggers placenta-derived protease-induced altered VE-cadherin reorganization at endothelial junctions in preeclampsia. Placenta. 2012;33:803-9 pubmed publisher

Arooj M, Thangapandian S, John S, Hwang S, Park J, Lee K. Computational studies of novel chymase inhibitors against cardiovascular and allergic diseases: mechanism and inhibition. Chem Biol Drug Des. 2012;80:862-75 pubmed publisher

de Souza D, Toso V, Campos M, Lara V, Oliver C, Jamur M. Expression of mast cell proteases correlates with mast cell maturation and angiogenesis during tumor progression. PLoS ONE. 2012;7:e40790 pubmed publisher

Wang H, Song W, Yang Y, Huang J, Hao B, Gao D, et al. [Application of serum total IgE, tryptase and chymase in the identification of death caused by drug anaphylactic shock]. Fa Yi Xue Za Zhi. 2012;28:167-71 pubmed

Ravingerová T, Carnická S, Nemcekova M, Ledvényiová V, Adameova A, Kelly T, et al. PPAR-alpha activation as a preconditioning-like intervention in rats in vivo confers myocardial protection against acute ischaemia-reperfusion injury: involvement of PI3K-Akt. Can J Physiol Pharmacol. 2012;90:1135-44 pubmed publisher

Vinje N, Namork E, Løvik M. Cross-allergic reactions to legumes in lupin and fenugreek-sensitized mice. Scand J Immunol. 2012;76:387-97 pubmed publisher

Wu Y, Yang H, Yang B, Yang K, Xiao C. Association of polymorphisms in prolylcarboxypeptidase and chymase genes with essential hypertension in the Chinese Han population. J Renin Angiotensin Aldosterone Syst. 2013;14:263-70 pubmed publisher

Rafiq K, Sherajee S, Fan Y, Fujisawa Y, Takahashi Y, Matsuura J, et al. Blood glucose level and survival in streptozotocin-treated human chymase transgenic mice. Chin J Physiol. 2011;54:30-5 pubmed

Takai S, Shiota N, Sakaguchi M, Muraguchi H, Matsumura E, Miyazaki M. Characterization of chymase from human vascular tissues. Clin Chim Acta. 1997;265:13-20 pubmed

Woodbury R, Everitt M, Neurath H. Mast cell proteases. Methods Enzymol. 1981;80 Pt C:588-609 pubmed

Powers J, Tanaka T, Harper J, Minematsu Y, Barker L, Lincoln D, et al. Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors. Biochemistry. 1985;24:2048-58 pubmed

Johnson L, Moon K, Eisenberg M. Purification to homogeneity of the human skin chymotryptic proteinase "chymase". Anal Biochem. 1986;155:358-64 pubmed