Reference |
---|
Siong Tan H, Anjum B, Shen H, Ghosh S, Yen P, Sinha R. Lysosomal inhibition attenuates peroxisomal gene transcription via suppression of PPARA and PPARGC1A levels. Autophagy. 2019;15:1455-1459 pubmed publisher
|
Meech R, Hu D, McKinnon R, Mubarokah S, Haines A, Nair P, et al. The UDP-Glycosyltransferase (UGT) Superfamily: New Members, New Functions, and Novel Paradigms. Physiol Rev. 2019;99:1153-1222 pubmed publisher
|
Gu M, Zhao P, Zhang S, Fan S, Yang L, Tong Q, et al. Betulinic acid alleviates endoplasmic reticulum stress-mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice. Br J Pharmacol. 2019;176:847-863 pubmed publisher
|
Bushel P, Paules R, Auerbach S. A Comparison of the TempO-Seq S1500+ Platform to RNA-Seq and Microarray Using Rat Liver Mode of Action Samples. Front Genet. 2018;9:485 pubmed publisher
|
Krzysiak T, Thomas L, Choi Y, Auclair S, Qian Y, Luan S, et al. An Insulin-Responsive Sensor in the SIRT1 Disordered Region Binds DBC1 and PACS-2 to Control Enzyme Activity. Mol Cell. 2018;72:985-998.e7 pubmed publisher
|
Shavva V, Mogilenko D, Nekrasova E, Trulioff A, Kudriavtsev I, Larionova E, et al. Tumor necrosis factor α stimulates endogenous apolipoprotein A-I expression and secretion by human monocytes and macrophages: role of MAP-kinases, NF-κB, and nuclear receptors PPARα and LXRs. Mol Cell Biochem. 2018;448:211-223 pubmed publisher
|
Feuer R, Vlaic S, Arlt J, Sawodny O, Dahmen U, Zanger U, et al. LEMming: A Linear Error Model to Normalize Parallel Quantitative Real-Time PCR (qPCR) Data as an Alternative to Reference Gene Based Methods. PLoS ONE. 2015;10:e0135852 pubmed publisher
|
Garcia RamÃrez M, Hernández C, Palomer X, Vázquez Carrera M, Simó R. Fenofibrate prevents the disruption of the outer blood retinal barrier through downregulation of NF-κB activity. Acta Diabetol. 2016;53:109-18 pubmed publisher
|
Gu Q, Yang X, Lin L, Li S, Li Q, Zhong S, et al. Genetic ablation of solute carrier family 7a3a leads to hepatic steatosis in zebrafish during fasting. Hepatology. 2014;60:1929-41 pubmed publisher
|
Yoo S, Abdelmegeed M, Song B. Activation of PPARα by Wy-14643 ameliorates systemic lipopolysaccharide-induced acute lung injury. Biochem Biophys Res Commun. 2013;436:366-71 pubmed publisher
|
Melis M, Scheggi S, Carta G, Madeddu C, Lecca S, Luchicchi A, et al. PPARα regulates cholinergic-driven activity of midbrain dopamine neurons via a novel mechanism involving α7 nicotinic acetylcholine receptors. J Neurosci. 2013;33:6203-11 pubmed publisher
|
Nan Y, Kong L, Ren W, Wang R, Du J, Li W, et al. Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol mediated liver fibrosis in mice. Lipids Health Dis. 2013;12:11 pubmed publisher
|
Funai K, Song H, Yin L, Lodhi I, Wei X, Yoshino J, et al. Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling. J Clin Invest. 2013;123:1229-40 pubmed publisher
|
El Jamal N, Dubuquoy L, Auwerx J, Bertin B, Desreumaux P. In vivo imaging reveals selective PPAR activity in the skin of peroxisome proliferator-activated receptor responsive element-luciferase reporter mice. Exp Dermatol. 2013;22:137-40 pubmed publisher
|
Thomas M, Burk O, Klumpp B, Kandel B, Damm G, Weiss T, et al. Direct transcriptional regulation of human hepatic cytochrome P450 3A4 (CYP3A4) by peroxisome proliferator-activated receptor alpha (PPARα). Mol Pharmacol. 2013;83:709-18 pubmed publisher
|
Mogilenko D, Kudriavtsev I, Shavva V, Dizhe E, Vilenskaya E, Efremov A, et al. Peroxisome proliferator-activated receptor ? positively regulates complement C3 expression but inhibits tumor necrosis factor ?-mediated activation of C3 gene in mammalian hepatic-derived cells. J Biol Chem. 2013;288:1726-38 pubmed publisher
|
Reichenbach G, Starzinski Powitz A, Sloane B, Doll M, Kippenberger S, Bernd A, et al. PPAR? agonist Wy14643 suppresses cathepsin B in human endothelial cells via transcriptional, post-transcriptional and post-translational mechanisms. Angiogenesis. 2013;16:223-33 pubmed publisher
|
Paulitschke V, Gruber S, Hofstätter E, Haudek Prinz V, Klepeisz P, Schicher N, et al. Proteome analysis identified the PPAR? ligand 15d-PGJ2 as a novel drug inhibiting melanoma progression and interfering with tumor-stroma interaction. PLoS ONE. 2012;7:e46103 pubmed publisher
|
Ringseis R, Keller J, Lukas I, Spielmann J, Most E, Couturier A, et al. Treatment with pharmacological PPARα agonists stimulates the ubiquitin proteasome pathway and myofibrillar protein breakdown in skeletal muscle of rodents. Biochim Biophys Acta. 2013;1830:2105-17 pubmed publisher
|
Qu C, Leung S, Vanhoutte P, Man R. Wy14643 improves vascular function in the aorta of the spontaneously hypertensive rat mainly by activating peroxisome proliferator-activated receptors alpha. Eur J Pharmacol. 2012;696:101-10 pubmed publisher
|
Ravingerová T, Carnická S, Nemcekova M, Ledvényiová V, Adameova A, Kelly T, et al. PPAR-alpha activation as a preconditioning-like intervention in rats in vivo confers myocardial protection against acute ischaemia-reperfusion injury: involvement of PI3K-Akt. Can J Physiol Pharmacol. 2012;90:1135-44 pubmed publisher
|
Ding J, Zhou Z, Zhou X, Zhou B, Wang L, Wang R, et al. Attenuation of acute pancreatitis by peroxisome proliferator-activated receptor-α in rats: the effect on Toll-like receptor signaling pathways. Pancreas. 2013;42:114-22 pubmed publisher
|
Zhang C, Gurevich I, Aneskievich B. Organotypic modeling of human keratinocyte response to peroxisome proliferators. Cells Tissues Organs. 2012;196:431-41 pubmed publisher
|
Kim B, Kim J, Kim H, Lee J, Choi K, Lee S. Co-treatment with retinyl retinoate and a PPARα agonist reduces retinoid dermatitis. Int J Dermatol. 2012;51:733-41 pubmed publisher
|
Chiba T, Takeuchi S, Esaki H, Yamamura K, Kurihara Y, Moroi Y, et al. Topical application of PPARα (but not β/δ or γ) suppresses atopic dermatitis in NC/Nga mice. Allergy. 2012;67:936-42 pubmed publisher
|
Masuda Y, Saotome D, Takada K, Sugimoto K, Sasaki T, Ishii H. Peroxisome proliferator-activated receptor-alpha agonists repress expression of thrombin-activatable fibrinolysis inhibitor by decreasing transcript stability. Thromb Haemost. 2012;108:74-85 pubmed publisher
|
Asavapanumas N, Kittayaruksakul S, Meetam P, Muanprasat C, Chatsudthipong V, Soodvilai S. Fenofibrate down-regulates renal OCT2-mediated organic cation transport via PPAR?-independent pathways. Drug Metab Pharmacokinet. 2012;27:513-9 pubmed
|
Montero T, Racordon D, Bravo L, Owen G, Bronfman M, Leisewitz A. PPAR? and PPAR? regulate the nucleoside transporter hENT1. Biochem Biophys Res Commun. 2012;419:405-11 pubmed publisher
|
Patterson A, Shah Y, Matsubara T, Krausz K, Gonzalez F. Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity. Hepatology. 2012;56:281-90 pubmed publisher
|
Clockaerts S, Bastiaansen Jenniskens Y, Feijt C, De Clerck L, Verhaar J, Zuurmond A, et al. Cytokine production by infrapatellar fat pad can be stimulated by interleukin 1? and inhibited by peroxisome proliferator activated receptor ? agonist. Ann Rheum Dis. 2012;71:1012-8 pubmed publisher
|
Georgiadi A, Boekschoten M, Muller M, Kersten S. Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart. Physiol Genomics. 2012;44:352-61 pubmed publisher
|
Papi A, Guarnieri T, Storci G, Santini D, Ceccarelli C, Taffurelli M, et al. Nuclear receptors agonists exert opposing effects on the inflammation dependent survival of breast cancer stem cells. Cell Death Differ. 2012;19:1208-19 pubmed publisher
|
Kong L, Ren W, Li W, Zhao S, Mi H, Wang R, et al. Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol induced steatohepatitis in mice. Lipids Health Dis. 2011;10:246 pubmed publisher
|
Gabler M, Schubert Zsilavecz M. Tertiary alkylamines as nucleophiles in substitution reactions at heteroaromatic halide during the synthesis of the highly potent pirinixic acid derivative 2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid (YS-121). Molecules. 2011;16:10013-28 pubmed publisher
|