product summary
company name :
MilliporeSigma
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, FLUKA, Sigma-Aldrich, Novabiochem, Guava, Roche Applied Science
product type :
antibody
product name :
Monoclonal Anti-HNK-1/N-CAM (CD57) antibody produced in mouse
catalog :
C6680
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
VC1.1
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 21
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:100; fig 1e
Jones I, Novikova L, Wiberg M, Carlsson L, Novikov L. Human Embryonic Stem Cell-derived Neural Crest Cells Promote Sprouting and Motor Recovery Following Spinal Cord Injury in Adult Rats. Cell Transplant. 2021;30:963689720988245 pubmed publisher
  • immunohistochemistry; human; 1:100; fig 3a
Naylor R, McGhee C, Cowan C, Davidson A, Holm T, Sherwin T. Derivation of Corneal Keratocyte-Like Cells from Human Induced Pluripotent Stem Cells. PLoS ONE. 2016;11:e0165464 pubmed publisher
  • western blot; human; fig 1
García Ayllón M, Botella López A, Cuchillo Ibañez I, Rábano A, Andreasen N, Blennow K, et al. HNK-1 Carrier Glycoproteins Are Decreased in the Alzheimer's Disease Brain. Mol Neurobiol. 2017;54:188-199 pubmed publisher
  • immunocytochemistry; human; 1:500; fig 3
Werner A, Iwasaki S, McGourty C, Medina Ruiz S, Teerikorpi N, Fedrigo I, et al. Cell-fate determination by ubiquitin-dependent regulation of translation. Nature. 2015;525:523-7 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 6
Kann M, Bae E, Lenz M, Li L, Trannguyen B, Schumacher V, et al. WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals. Development. 2015;142:1254-66 pubmed publisher
Trimarco J, Nelson S, Chaparian R, Wells A, Murray N, Azadi P, et al. Cellular glycan modification by B3GAT1 broadly restricts influenza virus infection. Nat Commun. 2022;13:6456 pubmed publisher
Spencer K, Belgacem Y, Visina O, Shim S, Genus H, Borodinsky L. Growth at Cold Temperature Increases the Number of Motor Neurons to Optimize Locomotor Function. Curr Biol. 2019;29:1787-1799.e5 pubmed publisher
Park Y, Snook J, Ostrin E, Kim S, Chen R, Frankfort B. Transcriptomic profiles of retinal ganglion cells are defined by the magnitude of intraocular pressure elevation in adult mice. Sci Rep. 2019;9:2594 pubmed publisher
Huang C, Huang W, Qiu X, Fernandes Ferreira da Silva F, Wang A, Patel S, et al. The Differentiation Stage of Transplanted Stem Cells Modulates Nerve Regeneration. Sci Rep. 2017;7:17401 pubmed publisher
Tongtako W, Lehmbecker A, Wang Y, Hahn K, Baumgartner W, Gerhauser I. Canine dorsal root ganglia satellite glial cells represent an exceptional cell population with astrocytic and oligodendrocytic properties. Sci Rep. 2017;7:13915 pubmed publisher
Steffensen N, Lehmbecker A, Gerhauser I, Wang Y, Carlson R, Tipold A, et al. Generation and characterization of highly purified canine Schwann cells from spinal nerve dorsal roots as potential new candidates for transplantation strategies. J Tissue Eng Regen Med. 2018;12:e422-e437 pubmed publisher
Lai F, Lau S, Wong J, Gui H, Wang R, Zhou T, et al. Correction of Hirschsprung-Associated Mutations in Human Induced Pluripotent Stem Cells Via Clustered Regularly Interspaced Short Palindromic Repeats/Cas9, Restores Neural Crest Cell Function. Gastroenterology. 2017;153:139-153.e8 pubmed publisher
Pei S, Liu L, Zhong Z, Wang H, Lin S, Shang J. Risk of prenatal depression and stress treatment: alteration on serotonin system of offspring through exposure to Fluoxetine. Sci Rep. 2016;6:33822 pubmed publisher
Rabadán M, Herrera A, Fanlo L, Usieto S, Carmona Fontaine C, Barriga E, et al. Delamination of neural crest cells requires transient and reversible Wnt inhibition mediated by Dact1/2. Development. 2016;143:2194-205 pubmed publisher
Ware M, Dupé V, Schubert F. Evolutionary Conservation of the Early Axon Scaffold in the Vertebrate Brain. Dev Dyn. 2015;244:1202-14 pubmed publisher
Mahadevan A, Welsh I, Sivakumar A, Gludish D, Shilvock A, Noden D, et al. The left-right Pitx2 pathway drives organ-specific arterial and lymphatic development in the intestine. Dev Cell. 2014;31:690-706 pubmed publisher
Dubaissi E, Rousseau K, Lea R, Soto X, Nardeosingh S, Schweickert A, et al. A secretory cell type develops alongside multiciliated cells, ionocytes and goblet cells, and provides a protective, anti-infective function in the frog embryonic mucociliary epidermis. Development. 2014;141:1514-25 pubmed publisher
Kreitzer F, Salomonis N, Sheehan A, Huang M, Park J, Spindler M, et al. A robust method to derive functional neural crest cells from human pluripotent stem cells. Am J Stem Cells. 2013;2:119-31 pubmed
Lindgren C, Newman Z, Morford J, Ryan S, Battani K, Su Z. Cyclooxygenase-2, prostaglandin E2 glycerol ester and nitric oxide are involved in muscarine-induced presynaptic enhancement at the vertebrate neuromuscular junction. J Physiol. 2013;591:4749-64 pubmed publisher
Li X, Chu J, Wang A, Zhu Y, Chu W, Yang L, et al. Uniaxial mechanical strain modulates the differentiation of neural crest stem cells into smooth muscle lineage on micropatterned surfaces. PLoS ONE. 2011;6:e26029 pubmed publisher
Bock P, Beineke A, Techangamsuwan S, Baumgartner W, Wewetzer K. Differential expression of HNK-1 and p75(NTR) in adult canine Schwann cells and olfactory ensheathing cells in situ but not in vitro. J Comp Neurol. 2007;505:572-85 pubmed
product information
Product No. :
C6680
Product Name :
Monoclonal Anti-HNK-1/N-CAM (CD57) antibody produced in mouse
Host :
mouse
Conjugate :
unconjugated
Antibody Type :
monoclonal
Clone Number (if monoclonal) :
VC1.1
Applications/Description :
Suitable for flow cytometry: 5 μL using 1 × 10 6 cells; immunohistochemistry (formalin-fixed, paraffin-embedded sections)
Species Reactivity :
rat, human, feline, mouse
Isotype :
IgM
Storage :
Store at 2-8°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA