This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Carbonic Anhydrase II human
catalog :
C6624
citations: 55
Reference
Desmarais J, Flamholz A, Blikstad C, Dugan E, Laughlin T, Oltrogge L, et al. DABs are inorganic carbon pumps found throughout prokaryotic phyla. Nat Microbiol. 2019;4:2204-2215 pubmed publisher
Malikowski T, Bosch J, Min S, Duffey M, Patel S. Carbonic anhydrase inhibitors in corneal endothelial transport. Invest Ophthalmol Vis Sci. 2014;55:2652-8 pubmed publisher
Rufo C, Moroz Y, Moroz O, Stöhr J, Smith T, Hu X, et al. Short peptides self-assemble to produce catalytic amyloids. Nat Chem. 2014;6:303-9 pubmed publisher
Liu H, Liu Z, Li J, Li Q, You C, Xu J. Relative quantitative expression of hypoxia-inducible factor 1α messenger ribonucleic acid in recurrent craniopharyngiomas. Neurol India. 2014;62:53-6 pubmed publisher
Zastrow M, Pecoraro V. Designing hydrolytic zinc metalloenzymes. Biochemistry. 2014;53:957-78 pubmed publisher
Capkova L, Koubkova L, Kodet R. Expression of carbonic anhydrase IX (CAIX) in malignant mesothelioma. An immunohistochemical and immunocytochemical study. Neoplasma. 2014;61:161-9 pubmed
Luong Player A, Liu H, Wang H, Lin F. Immunohistochemical reevaluation of carbonic anhydrase IX (CA IX) expression in tumors and normal tissues. Am J Clin Pathol. 2014;141:219-25 pubmed publisher
Klier M, Andes F, Deitmer J, Becker H. Intracellular and extracellular carbonic anhydrases cooperate non-enzymatically to enhance activity of monocarboxylate transporters. J Biol Chem. 2014;289:2765-75 pubmed publisher
Laguna M. Re: carbonic anhydrase IX (CAIX) is not an independent predictor of outcome in patients with clear cell renal cell carcinoma (ccRCC) after long-term follow-up. J Urol. 2014;191:54-5 pubmed publisher
Ostheimer C, Bache M, Güttler A, Kotzsch M, Vordermark D. A pilot study on potential plasma hypoxia markers in the radiotherapy of non-small cell lung cancer. Osteopontin, carbonic anhydrase IX and vascular endothelial growth factor. Strahlenther Onkol. 2014;190:276-82 pubmed publisher
Rodrigues G, Feijó D, Bozza M, Pan P, Vullo D, Parkkila S, et al. Design, synthesis, and evaluation of hydroxamic acid derivatives as promising agents for the management of Chagas disease. J Med Chem. 2014;57:298-308 pubmed publisher
Herrou J, Crosson S. Molecular structure of the Brucella abortus metalloprotein RicA, a Rab2-binding virulence effector. Biochemistry. 2013;52:9020-8 pubmed publisher
Gu M, Kwon K. Carbonic anhydrase IX expression is associated with favorable prognostic factors in small intestinal carcinoma. J Histochem Cytochem. 2014;62:205-10 pubmed publisher
Carroux C, Rankin G, Moeker J, Bornaghi L, Katneni K, Morizzi J, et al. A prodrug approach toward cancer-related carbonic anhydrase inhibition. J Med Chem. 2013;56:9623-34 pubmed publisher
Wachters J, Schrijvers M, Slagter Menkema L, Mastik M, de Bock G, Langendijk J, et al. Prognostic significance of HIF-1a, CA-IX, and OPN in T1-T2 laryngeal carcinoma treated with radiotherapy. Laryngoscope. 2013;123:2154-60 pubmed
Tobal J, Balieiro M. Role of carbonic anhydrases in pathogenic micro-organisms: a focus on Aspergillus fumigatus. J Med Microbiol. 2014;63:15-27 pubmed publisher
Gonzalez J, Fisher S. Carbonic anhydrases in industrial applications. Subcell Biochem. 2014;75:405-26 pubmed publisher
Alterio V, Monti S, De Simone G. Thermal-stable carbonic anhydrases: a structural overview. Subcell Biochem. 2014;75:387-404 pubmed publisher
Swenson E. Carbonic anhydrase inhibitors and high altitude illnesses. Subcell Biochem. 2014;75:361-86 pubmed publisher
Scozzafava A, Supuran C. Glaucoma and the applications of carbonic anhydrase inhibitors. Subcell Biochem. 2014;75:349-59 pubmed publisher
Poulsen S, Davis R. Natural products that inhibit carbonic anhydrase. Subcell Biochem. 2014;75:325-47 pubmed publisher
McKenna R, Supuran C. Carbonic anhydrase inhibitors drug design. Subcell Biochem. 2014;75:291-323 pubmed publisher
Ruusuvuori E, Kaila K. Carbonic anhydrases and brain pH in the control of neuronal excitability. Subcell Biochem. 2014;75:271-90 pubmed publisher
McDonald P, Dedhar S. Carbonic anhydrase IX (CAIX) as a mediator of hypoxia-induced stress response in cancer cells. Subcell Biochem. 2014;75:255-69 pubmed publisher
Tafreshi N, Lloyd M, Bui M, Gillies R, Morse D. Carbonic anhydrase IX as an imaging and therapeutic target for tumors and metastases. Subcell Biochem. 2014;75:221-54 pubmed publisher
Benej M, Pastorekova S, Pastorek J. Carbonic anhydrase IX: regulation and role in cancer. Subcell Biochem. 2014;75:199-219 pubmed publisher
Sh Ali A, Al Mashta S. Cerebral calcification, osteopetrosis and renal tubular acidosis: is it carbonic anhydrase-II deficiency?. Saudi J Kidney Dis Transpl. 2013;24:561-5 pubmed
Shah G, Rubbelke T, Hendin J, Nguyen H, Waheed A, Shoemaker J, et al. Targeted mutagenesis of mitochondrial carbonic anhydrases VA and VB implicates both enzymes in ammonia detoxification and glucose metabolism. Proc Natl Acad Sci U S A. 2013;110:7423-8 pubmed publisher
Langereis J, Zomer A, Stunnenberg H, Burghout P, Hermans P. Nontypeable Haemophilus influenzae carbonic anhydrase is important for environmental and intracellular survival. J Bacteriol. 2013;195:2737-46 pubmed publisher
Onnis B, Fer N, Rapisarda A, Perez V, Melillo G. Autocrine production of IL-11 mediates tumorigenicity in hypoxic cancer cells. J Clin Invest. 2013;123:1615-29 pubmed publisher
Kumar R, Hendrick W, Correll J, Patterson A, Melville S, Ferry J. Biochemistry and physiology of the ? class carbonic anhydrase (Cpb) from Clostridium perfringens strain 13. J Bacteriol. 2013;195:2262-9 pubmed publisher
Schroeder M, Ali M, Hulikova A, Supuran C, Clarke K, Vaughan Jones R, et al. Extramitochondrial domain rich in carbonic anhydrase activity improves myocardial energetics. Proc Natl Acad Sci U S A. 2013;110:E958-67 pubmed publisher
Drake J, Mass T, Haramaty L, Zelzion E, Bhattacharya D, Falkowski P. Proteomic analysis of skeletal organic matrix from the stony coral Stylophora pistillata. Proc Natl Acad Sci U S A. 2013;110:3788-93 pubmed publisher
Ragunathan P, Raghunath G, Kuramitsu S, Yokoyama S, Kumarevel T, Ponnuraj K. Crystallization, characterization and preliminary X-ray crystallographic analysis of GK2848, a putative carbonic anhydrase of Geobacillus kaustophilus. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013;69:162-4 pubmed publisher
Talento R, Hewan Lowe K, Yin M. Evaluation of morphologically unclassified renal cell carcinoma with electron microscopy and novel renal markers: implications for tumor reclassification. Ultrastruct Pathol. 2013;37:70-6 pubmed publisher
Birkhäuser F, Koya R, Neufeld C, Rampersaud E, Lu X, Micewicz E, et al. Dendritic cell-based immunotherapy in prevention and treatment of renal cell carcinoma: efficacy, safety, and activity of Ad-GM·CAIX in immunocompetent mouse models. J Immunother. 2013;36:102-11 pubmed publisher
Papi A, Storci G, Guarnieri T, De Carolis S, Bertoni S, Avenia N, et al. Peroxisome proliferator activated receptor-α/hypoxia inducible factor-1α interplay sustains carbonic anhydrase IX and apoliprotein E expression in breast cancer stem cells. PLoS ONE. 2013;8:e54968 pubmed publisher
Horner T, Lee R, Henderson G, Rickaby R. Nonspecific uptake and homeostasis drive the oceanic cadmium cycle. Proc Natl Acad Sci U S A. 2013;110:2500-5 pubmed publisher
Schütze D, Milde Langosch K, Witzel I, Rody A, Karn T, Schmidt M, et al. Relevance of cellular and serum carbonic anhydrase IX in primary breast cancer. J Cancer Res Clin Oncol. 2013;139:747-54 pubmed publisher
Burghout P, Zomer A, van der Gaast de Jongh C, Janssen Megens E, Francoijs K, Stunnenberg H, et al. Streptococcus pneumoniae folate biosynthesis responds to environmental CO2 levels. J Bacteriol. 2013;195:1573-82 pubmed publisher
Lounnas N, Rosilio C, Nebout M, Mary D, Griessinger E, Neffati Z, et al. Pharmacological inhibition of carbonic anhydrase XII interferes with cell proliferation and induces cell apoptosis in T-cell lymphomas. Cancer Lett. 2013;333:76-88 pubmed publisher
Bian Y, Wei G, Chang T. Lowering of elevated tissue PCO2 in a hemorrhagic shock rat model after reinfusion of a novel nanobiotechnological polyhemoglobin-superoxide dismutase-catalase-carbonic anhydrase that is an oxygen and a carbon dioxide carrier with enhanced antioxidan. Artif Cells Nanomed Biotechnol. 2013;41:60-8 pubmed publisher
Kaya A, Gunel N, Benekli M, Akyurek N, Buyukberber S, Tatli H, et al. Hypoxia inducible factor-1 alpha and carbonic anhydrase IX overexpression are associated with poor survival in breast cancer patients. J BUON. 2012;17:663-8 pubmed
Mayer A, Hockel M, Schlischewsky N, Schmidberger H, Horn L, Vaupel P. Lacking hypoxia-mediated downregulation of E-cadherin in cancers of the uterine cervix. Br J Cancer. 2013;108:402-8 pubmed publisher
Shan X, Wang D, Chen J, Xiao X, Jiang Y, Wang Y, et al. Necrosis degree displayed in computed tomography images correlated with hypoxia and angiogenesis in breast cancer. J Comput Assist Tomogr. 2013;37:22-8 pubmed publisher
Maret W. Zinc biochemistry: from a single zinc enzyme to a key element of life. Adv Nutr. 2013;4:82-91 pubmed publisher
Hofmann L, Straub S, Bischof K. Elevated CO2 levels affect the activity of nitrate reductase and carbonic anhydrase in the calcifying rhodophyte Corallina officinalis. J Exp Bot. 2013;64:899-908 pubmed publisher
Vermeulen J, Kornegoor R, van der Wall E, van der Groep P, van Diest P. Differential expression of growth factor receptors and membrane-bound tumor markers for imaging in male and female breast cancer. PLoS ONE. 2013;8:e53353 pubmed publisher
Stander B, Joubert F, Tu C, Sippel K, McKenna R, Joubert A. In vitro evaluation of ESE-15-ol, an estradiol analogue with nanomolar antimitotic and carbonic anhydrase inhibitory activity. PLoS ONE. 2012;7:e52205 pubmed publisher
Liao S, Rodgers W, Kauderer J, Darcy K, Carter R, Susumu N, et al. Endocervical glandular neoplasia associated with lobular endocervical glandular hyperplasia is HPV-independent and correlates with carbonic anhydrase-IX expression: a Gynaecological Oncology Group Study. Br J Cancer. 2013;108:613-20 pubmed publisher
Alvarez B, Quon A, Mullen J, Casey J. Quantification of carbonic anhydrase gene expression in ventricle of hypertrophic and failing human heart. BMC Cardiovasc Disord. 2013;13:2 pubmed publisher
McCranor B, Bozym R, Vitolo M, Fierke C, Bambrick L, Polster B, et al. Quantitative imaging of mitochondrial and cytosolic free zinc levels in an in vitro model of ischemia/reperfusion. J Bioenerg Biomembr. 2012;44:253-63 pubmed publisher
Ranjbar S, Ghobadi S, Khodarahmi R, Nemati H. Spectroscopic characterization of furosemide binding to human carbonic anhydrase II. Int J Biol Macromol. 2012;50:910-7 pubmed publisher
Chiang W, Chu S, Yang S, Li M, Lai J, Yang S, et al. The aberrant expression of cytosolic carbonic anhydrase and its clinical significance in human non-small cell lung cancer. Cancer Lett. 2002;188:199-205 pubmed
Murakami H, Sly W. Purification and characterization of human salivary carbonic anhydrase. J Biol Chem. 1987;262:1382-8 pubmed
product information
Catalog Number :
C6624
Product Name :
Carbonic Anhydrase II human
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
recombinant, expressed in E. coli, buffered aqueous solution
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA