This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt
catalog :
C5438
citations: 23
Reference
Chen Y, Harty G, Zheng Y, Iyer S, Sugihara S, Sangaralingham S, et al. CRRL269. Circ Res. 2019;124:1462-1472 pubmed publisher
Ishikawa K, Hara T, Kato K, Shimomura T, Omori K. Involvement of natriuretic peptide system in C2C12 myocytes. Mol Cell Biochem. 2019;456:15-27 pubmed publisher
Schramm A, Mueller Thuemen P, Littmann T, Harloff M, Ozawa T, Schlossmann J. Establishing a Split Luciferase Assay for Proteinkinase G (PKG) Interaction Studies. Int J Mol Sci. 2018;19: pubmed publisher
Wu M, Wu Y, Qian H, Tao Y, Pang J, Wang Y, et al. Type II cGMP‑dependent protein kinase inhibits the migration, invasion and proliferation of several types of human cancer cells. Mol Med Rep. 2017;16:5729-5737 pubmed publisher
Campbell J, Henning P, Franz E, Sankaran B, Herberg F, Kim C. Structural Basis of Analog Specificity in PKG I and II. ACS Chem Biol. 2017;12:2388-2398 pubmed publisher
Gabitova D, Shaidullov I, Sabirullina G, Shafigullin M, Sitdikov F, Sitdikova G. Role of Cyclic Nucleotides in the Effect of Hydrogen Sulfide on Contractions of Rat Jejunum. Bull Exp Biol Med. 2017;163:14-17 pubmed publisher
Kalyanaraman H, Ramdani G, Joshua J, Schall N, Boss G, Cory E, et al. A Novel, Direct NO Donor Regulates Osteoblast and Osteoclast Functions and Increases Bone Mass in Ovariectomized Mice. J Bone Miner Res. 2017;32:46-59 pubmed publisher
Pablos P, Mendiguren A, Pineda J. Contribution of nitric oxide-dependent guanylate cyclase and reactive oxygen species signaling pathways to desensitization of μ-opioid receptors in the rat locus coeruleus. Neuropharmacology. 2015;99:422-31 pubmed publisher
Wang Y, Chen Y, Wu M, Lan T, Wu Y, Li Y, et al. Type II cyclic guanosine monophosphate-dependent protein kinase inhibits Rac1 activation in gastric cancer cells. Oncol Lett. 2015;10:502-508 pubmed
Yao X, Wu Y, Zhu M, Qian H, Chen Y. Nitric oxide/cyclic guanosine monophosphate inducers sodium nitroprusside and L-arginine inhibit the proliferation of gastric cancer cells via the activation of type II cyclic guanosine monophosphate-dependent protein kinase. Oncol Lett. 2015;10:479-484 pubmed
Stahl K, Stahl M, de Jonge H, Forrest J. ANP and CNP activate CFTR expressed in Xenopus laevis oocytes by direct activation of PKA. J Recept Signal Transduct Res. 2015;35:493-504 pubmed publisher
Hoffmann L, Etzrodt J, Willkomm L, Sanyal A, Scheja L, Fischer A, et al. Stimulation of soluble guanylyl cyclase protects against obesity by recruiting brown adipose tissue. Nat Commun. 2015;6:7235 pubmed publisher
Liu S, Ngo D, Chong C, Amarasekera A, Procter N, Licari G, et al. Suppression of neutrophil superoxide generation by BNP is attenuated in acute heart failure: a case for 'BNP resistance'. Eur J Heart Fail. 2015;17:475-83 pubmed publisher
Joshua J, Schwaerzer G, Kalyanaraman H, Cory E, Sah R, Li M, et al. Soluble guanylate cyclase as a novel treatment target for osteoporosis. Endocrinology. 2014;155:4720-30 pubmed publisher
Sodhi P, Hartwick A. Adenosine modulates light responses of rat retinal ganglion cell photoreceptors througha cAMP-mediated pathway. J Physiol. 2014;592:4201-20 pubmed publisher
Nygaard G, Herfindal L, Kopperud R, Aragay A, Holmsen H, Døskeland S, et al. Time-dependent inhibitory effects of cGMP-analogues on thrombin-induced platelet-derived microparticles formation, platelet aggregation, and P-selectin expression. Biochem Biophys Res Commun. 2014;449:357-63 pubmed publisher
Hall G, Rowell J, Farinelli F, Gbadegesin R, Lavin P, Wu G, et al. Phosphodiesterase 5 inhibition ameliorates angiontensin II-induced podocyte dysmotility via the protein kinase G-mediated downregulation of TRPC6 activity. Am J Physiol Renal Physiol. 2014;306:F1442-50 pubmed publisher
Thorpe R, Stockman S, Williams J, Lincoln T, Pearce W. Hypoxic depression of PKG-mediated inhibition of serotonergic contraction in ovine carotid arteries. Am J Physiol Regul Integr Comp Physiol. 2013;304:R734-43 pubmed publisher
He P, Zeng M, Curry F. cGMP modulates basal and activated microvessel permeability independently of [Ca2+]i. Am J Physiol. 1998;274:H1865-74 pubmed publisher
Suhasini M, Li H, Lohmann S, Boss G, Pilz R. Cyclic-GMP-dependent protein kinase inhibits the Ras/Mitogen-activated protein kinase pathway. Mol Cell Biol. 1998;18:6983-94 pubmed
VanUffelen B, de Koster B, Elferink J. Interaction of cyclic GMP and cyclic AMP during neutrophil migration: involvement of phosphodiesterase type III. Biochem Pharmacol. 1998;56:1061-3 pubmed
Hood J, Granger H. Protein kinase G mediates vascular endothelial growth factor-induced Raf-1 activation and proliferation in human endothelial cells. J Biol Chem. 1998;273:23504-8 pubmed
Wei J, Cohen E, Genieser H, Barnstable C. Substituted cGMP analogs can act as selective agonists of the rod photoreceptor cGMP-gated cation channel. J Mol Neurosci. 1998;10:53-64 pubmed
product information
Catalog Number :
C5438
Product Name :
8-(4-Chlorophenylthio)-guanosine 3′,5′-cyclic monophosphate sodium salt
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
Product Description :
≥95% (HPLC), powder
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA