This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
chemical
product name :
Cyclobenzaprine hydrochloride
catalog :
C4542
citations: 31
Reference
Alencar F, Viana P, Zamperini C, Becker A. Patient education and self-care for the management of jaw pain upon awakening: a randomized controlled clinical trial comparing the effectiveness of adding pharmacologic treatment with cyclobenzaprine or tizanidine. J Oral Facial Pain Headache. 2014;28:119-27 pubmed publisher
Di Rago M, Saar E, Rodda L, Turfus S, Kotsos A, Gerostamoulos D, et al. Fast targeted analysis of 132 acidic and neutral drugs and poisons in whole blood using LC-MS/MS. Forensic Sci Int. 2014;243:35-43 pubmed publisher
Bicknell L, Sanches M, Schatte D. Erythema multiforme vs. DRESS syndrome associated with the combined use of lamotrigine and cyclobenzaprine: a case report. Int J Psychiatry Med. 2012;44:305-14 pubmed
Hernandez diaz S, Su Y, Mitchell A, Kelley K, Calafat A, Hauser R. Medications as a potential source of exposure to phthalates among women of childbearing age. Reprod Toxicol. 2013;37:1-5 pubmed publisher
Sheikh M, Kunka C, Ota K. Treatment of levator ani syndrome with cyclobenzaprine. Ann Pharmacother. 2012;46:e29 pubmed publisher
Vanneste S, Figueiredo R, De Ridder D. Treatment of tinnitus with cyclobenzaprine: an open-label study. Int J Clin Pharmacol Ther. 2012;50:338-44 pubmed
Ramadan N, Zaazaa H, Merey H. Microsized graphite sensors for potentiometric determination of cyclobenzaprine hydrochloride in pure powder, tablets, and plasma. J AOAC Int. 2011;94:1807-14 pubmed
Coelho C, Figueiredo R, Frank E, Burger J, Schecklmann M, Landgrebe M, et al. Reduction of tinnitus severity by the centrally acting muscle relaxant cyclobenzaprine: an open-label pilot study. Audiol Neurootol. 2012;17:179-88 pubmed publisher
Thomas R. Sleep as a window into the world of fibromyalgia syndrome. J Rheumatol. 2011;38:2499-500 pubmed publisher
Xiang Y, Zhou L, Qian Z, Peng K, Li D, Chen X, et al. Determination of cyclobenzaprine in human plasma by liquid chromatography-electrospray ionization tandem mass spectrometry and its application in a pharmacokinetic study. Biomed Chromatogr. 2012;26:1083-8 pubmed publisher
Bebarta V, MADDRY J, Borys D, Morgan D. Incidence of tricyclic antidepressant-like complications after cyclobenzaprine overdose. Am J Emerg Med. 2012;30:374 pubmed publisher
Borges N, Rezende V, Santana J, Moreira R, Moreira R, Moreno P, et al. Chlorpromazine quantification in human plasma by UPLC-electrospray ionization tandem mass spectrometry. Application to a comparative pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2011;879:3728-34 pubmed publisher
Abernethy D, Bai J, Burkhart K, Xie H, Zhichkin P. Integration of diverse data sources for prediction of adverse drug events. Clin Pharmacol Ther. 2011;90:645-6 pubmed publisher
Mestres J, Seifert S, Oprea T. Linking pharmacology to clinical reports: cyclobenzaprine and its possible association with serotonin syndrome. Clin Pharmacol Ther. 2011;90:662-5 pubmed publisher
de Santana Santos T, Calazans A, Martins Filho P, Silva L, de Oliveira e Silva E, Gomes A. Evaluation of the muscle relaxant cyclobenzaprine after third-molar extraction. J Am Dent Assoc. 2011;142:1154-62 pubmed
Moldofsky H, Harris H, Archambault W, Kwong T, LEDERMAN S. Effects of bedtime very low dose cyclobenzaprine on symptoms and sleep physiology in patients with fibromyalgia syndrome: a double-blind randomized placebo-controlled study. J Rheumatol. 2011;38:2653-63 pubmed publisher
Darwish M, Hellriegel E. Steady-state pharmacokinetics of once-daily cyclobenzaprine extended release: a randomized, double-blind, 2-period crossover study in healthy volunteers. Clin Ther. 2011;33:746-53 pubmed publisher
Pedroso J, Braga Neto P, Abrahão A, Rivero R, Abdalla C, Abdala N, et al. Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS): typical clinical and neuroimaging features in a Brazilian family. Arq Neuropsiquiatr. 2011;69:288-91 pubmed
Landy S, Altman C, Xie F. Time to recovery in patients with acute painful musculoskeletal conditions treated with extended-release or immediate-release cyclobenzaprine. Adv Ther. 2011;28:295-303 pubmed publisher
Carre Pierrat M, Lafoux A, Tanniou G, Chambonnier L, Divet A, Fougerousse F, et al. Pre-clinical study of 21 approved drugs in the mdx mouse. Neuromuscul Disord. 2011;21:313-27 pubmed publisher
Darwish M, Hellriegel E. Pharmacokinetic profile of once-daily cyclobenzaprine extended-release. Expert Opin Drug Metab Toxicol. 2010;6:1425-36 pubmed publisher
Bebarta V, MADDRY J, Borys D, Morgan D. Incidence of tricyclic antidepressant-like complications after cyclobenzaprine overdose. Am J Emerg Med. 2011;29:645-9 pubmed publisher
Weil A, Ruoff G, Nalamachu S, Altman C, Xie F, Taylor D. Efficacy and tolerability of cyclobenzaprine extended release for acute muscle spasm: a pooled analysis. Postgrad Med. 2010;122:158-69 pubmed publisher
Khwaja S, Minnerop M, Singer A. Comparison of ibuprofen, cyclobenzaprine or both in patients with acute cervical strain: a randomized controlled trial. CJEM. 2010;12:39-44 pubmed
Menard Katcher C, Henretig F, Osterhoudt K. A 19-month-old girl with recurrent illness: over the hills and through the woods. Pediatr Emerg Care. 2009;25:869-71 pubmed publisher
Robbins M, Grosberg B. Menstrual-related nummular headache. Cephalalgia. 2010;30:507-8 pubmed publisher
Reuss R, Reuter I, Jauss M, Fischer F, Muller S, Stolz E. Torticollis under cyclobenzaprine. Pharmacology. 2009;84:91-2 pubmed publisher
Leite F, Atallah A, El Dib R, Grossmann E, Januzzi E, Andriolo R, et al. Cyclobenzaprine for the treatment of myofascial pain in adults. Cochrane Database Syst Rev. 2009;:CD006830 pubmed publisher
Gillman P. Is there sufficient evidence to suggest cyclobenzaprine might be implicated in causing serotonin toxicity?. Am J Emerg Med. 2009;27:509-10; author reply 510 pubmed publisher
Toth P, Urtis J. Commonly used muscle relaxant therapies for acute low back pain: a review of carisoprodol, cyclobenzaprine hydrochloride, and metaxalone. Clin Ther. 2004;26:1355-67 pubmed
Kobayashi H, Hasegawa Y, Ono H. Cyclobenzaprine, a centrally acting muscle relaxant, acts on descending serotonergic systems. Eur J Pharmacol. 1996;311:29-35 pubmed
product information
Catalog Number :
C4542
Product Name :
Cyclobenzaprine hydrochloride
Product Type :
SMALL MOLECULES
Product Group :
Protein & Pathway Technologies
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA