This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
protein
product name :
Cyclophilin A human
catalog :
C3805
citations: 59
Reference
Nath P, Dong G, Braiman A, Isakov N. Immunophilins control T lymphocyte adhesion and migration by regulating CrkII binding to C3G. J Immunol. 2014;193:3966-77 pubmed publisher
Saio T, Guan X, Rossi P, Economou A, Kalodimos C. Structural basis for protein antiaggregation activity of the trigger factor chaperone. Science. 2014;344:1250494 pubmed publisher
Gamerdinger M, Deuerling E. Biochemistry. Trigger factor flexibility. Science. 2014;344:590-1 pubmed publisher
Yun H, Kim J, Kim G, Choi H. Prolyl-isomerase Pin1 impairs trastuzumab sensitivity by up-regulating fatty acid synthase expression. Anticancer Res. 2014;34:1409-16 pubmed
Yoon W, Cho Y, Kim W, Bae H, Islam R, Woo K, et al. Prolyl isomerase Pin1-mediated conformational change and subnuclear focal accumulation of Runx2 are crucial for fibroblast growth factor 2 (FGF2)-induced osteoblast differentiation. J Biol Chem. 2014;289:8828-38 pubmed publisher
Jung C, Kim Y, Lee K, Im H. Retarded protein folding of the human Z-type ??-antitrypsin variant is suppressed by Cpr2p. Biochem Biophys Res Commun. 2014;445:191-5 pubmed publisher
Ueda K, Fujiki K, Shirahige K, Gomez Sanchez C, Fujita T, Nangaku M, et al. Genome-wide analysis of murine renal distal convoluted tubular cells for the target genes of mineralocorticoid receptor. Biochem Biophys Res Commun. 2014;445:132-7 pubmed publisher
Pihlajamaa P, Sahu B, Lyly L, Aittomäki V, Hautaniemi S, Janne O. Tissue-specific pioneer factors associate with androgen receptor cistromes and transcription programs. EMBO J. 2014;33:312-26 pubmed publisher
Cho K, Patil H, Senda E, Wang J, Yi H, Qiu S, et al. Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis. J Biol Chem. 2014;289:4600-25 pubmed publisher
Toko H, Hariharan N, Konstandin M, Ormachea L, McGregor M, Gude N, et al. Differential regulation of cellular senescence and differentiation by prolyl isomerase Pin1 in cardiac progenitor cells. J Biol Chem. 2014;289:5348-56 pubmed publisher
King A, Swain T, Mao Z, Udoh U, Oliva C, Betancourt A, et al. Involvement of the mitochondrial permeability transition pore in chronic ethanol-mediated liver injury in mice. Am J Physiol Gastrointest Liver Physiol. 2014;306:G265-77 pubmed publisher
Kumanogoh A, Kikutani H. Immunological functions of the neuropilins and plexins as receptors for semaphorins. Nat Rev Immunol. 2013;13:802-14 pubmed
Lam M, Lau E, Liem D, Ping P. Cyclophilin D and acetylation: a new link in cardiac signaling. Circ Res. 2013;113:1268-9 pubmed publisher
Park S, Xiao H, Lei M. Nuclear FKBPs, Fpr3 and Fpr4 affect genome-wide genes transcription. Mol Genet Genomics. 2014;289:125-36 pubmed publisher
Ge X, Lyu Z, Liu Y, Wang R, Zhao X, Fu X, et al. Identification of FkpA as a key quality control factor for the biogenesis of outer membrane proteins under heat shock conditions. J Bacteriol. 2014;196:672-80 pubmed publisher
Zucchelli C, Tamburri S, Quilici G, Palagano E, Berardi A, Saare M, et al. Structure of human Sp140 PHD finger: an atypical fold interacting with Pin1. FEBS J. 2014;281:216-31 pubmed publisher
Grúas C, Llambí S, Arruga M. Detection of Legionella spp. and Legionella pneumophila in water samples of Spain by specific real-time PCR. Arch Microbiol. 2014;196:63-71 pubmed publisher
Guito J, Gavina A, Palmeri D, Lukac D. The cellular peptidyl-prolyl cis/trans isomerase Pin1 regulates reactivation of Kaposi's sarcoma-associated herpesvirus from latency. J Virol. 2014;88:547-58 pubmed publisher
Bitomsky N, Conrad E, Moritz C, Polonio Vallon T, Sombroek D, Schultheiss K, et al. Autophosphorylation and Pin1 binding coordinate DNA damage-induced HIPK2 activation and cell death. Proc Natl Acad Sci U S A. 2013;110:E4203-12 pubmed publisher
Petrovich E, Asher C, Garty H. Induction of FKBP51 by aldosterone in intestinal epithelium. J Steroid Biochem Mol Biol. 2014;139:78-87 pubmed publisher
Suhanovsky M, Teschke C. An intramolecular chaperone inserted in bacteriophage P22 coat protein mediates its chaperonin-independent folding. J Biol Chem. 2013;288:33772-83 pubmed publisher
Wang H, Fu J, Lee Y, Lu P. Hyperthermia stress activates heat shock protein expression via propyl isomerase 1 regulation with heat shock factor 1. Mol Cell Biol. 2013;33:4889-99 pubmed publisher
Lee S, Choi Y, Kim Y, Choi H, Yeo C, Lee K. Prolyl isomerase Pin1 enhances osteoblast differentiation through Runx2 regulation. FEBS Lett. 2013;587:3640-7 pubmed publisher
Miao M, Reichheld S, Muiznieks L, Huang Y, Keeley F. Elastin binding protein and FKBP65 modulate in vitro self-assembly of human tropoelastin. Biochemistry. 2013;52:7731-41 pubmed publisher
Raghuram N, Strickfaden H, McDonald D, Williams K, Fang H, Mizzen C, et al. Pin1 promotes histone H1 dephosphorylation and stabilizes its binding to chromatin. J Cell Biol. 2013;203:57-71 pubmed publisher
Zhang X, Zhang B, Gao J, Wang X, Liu Z. Regulation of the microRNA 200b (miRNA-200b) by transcriptional regulators PEA3 and ELK-1 protein affects expression of Pin1 protein to control anoikis. J Biol Chem. 2013;288:32742-52 pubmed publisher
Wang Y, Kirschner A, Fabian A, Gopalakrishnan R, Kress C, Hoogeland B, et al. Increasing the efficiency of ligands for FK506-binding protein 51 by conformational control. J Med Chem. 2013;56:3922-35 pubmed publisher
Oh J, Malter J. Pin1-FADD interactions regulate Fas-mediated apoptosis in activated eosinophils. J Immunol. 2013;190:4937-45 pubmed publisher
Choi Y, Park T, Kim H, Lim I. Signals regulating necrosis of cardiomyoblast by BTG2(/TIS21/PC3) via activation of GSK3? and opening of mitochondrial permeability transition pore in response to H2O2. Biochem Biophys Res Commun. 2013;434:559-65 pubmed publisher
Roca F, Ramakrishnan L. TNF dually mediates resistance and susceptibility to mycobacteria via mitochondrial reactive oxygen species. Cell. 2013;153:521-34 pubmed publisher
Jordan B. [Is resilience an epigenetic phenomenon?]. Med Sci (Paris). 2013;29:325-8 pubmed publisher
Toko H, Konstandin M, Doroudgar S, Ormachea L, Joyo E, Joyo A, et al. Regulation of cardiac hypertrophic signaling by prolyl isomerase Pin1. Circ Res. 2013;112:1244-52 pubmed publisher
Parone P, Da Cruz S, Han J, McAlonis Downes M, Vetto A, Lee S, et al. Enhancing mitochondrial calcium buffering capacity reduces aggregation of misfolded SOD1 and motor neuron cell death without extending survival in mouse models of inherited amyotrophic lateral sclerosis. J Neurosci. 2013;33:4657-71 pubmed publisher
Féraudet Tarisse C, Väisänen Tunkelrott M, Moreau K, Lamourette P, Creminon C, Volland H. Pathogen-free screening of bacteria-specific hybridomas for selecting high-quality monoclonal antibodies against pathogen bacteria as illustrated for Legionella pneumophila. J Immunol Methods. 2013;391:81-94 pubmed publisher
Luo Y, Nie Y, Shi H, Ni Z, Wang Q, Wang J, et al. PTPA activates protein phosphatase-2A through reducing its phosphorylation at tyrosine-307 with upregulation of protein tyrosine phosphatase 1B. Biochim Biophys Acta. 2013;1833:1235-43 pubmed publisher
Fani N, Gutman D, Tone E, Almli L, Mercer K, Davis J, et al. FKBP5 and attention bias for threat: associations with hippocampal function and shape. JAMA Psychiatry. 2013;70:392-400 pubmed publisher
Li J, Richter K, Reinstein J, Buchner J. Integration of the accelerator Aha1 in the Hsp90 co-chaperone cycle. Nat Struct Mol Biol. 2013;20:326-31 pubmed publisher
Lucchetti C, Caligiuri I, Toffoli G, Giordano A, Rizzolio F. The prolyl isomerase Pin1 acts synergistically with CDK2 to regulate the basal activity of estrogen receptor ? in breast cancer. PLoS ONE. 2013;8:e55355 pubmed publisher
Guo L, Du H, Yan S, Wu X, McKhann G, Chen J, et al. Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimer's neurons. PLoS ONE. 2013;8:e54914 pubmed publisher
Quyen B, Choi H, Kang K. Pin1 is required for ultraviolet A-stimulated cyclooxygenase-2 induction in mouse epidermal cells. Cancer Lett. 2013;335:31-40 pubmed publisher
Siegelin M. Inhibition of the mitochondrial Hsp90 chaperone network: a novel, efficient treatment strategy for cancer?. Cancer Lett. 2013;333:133-46 pubmed publisher
Gunnarsen K, Kristinsson S, Justesen S, Frigstad T, Buus S, Bogen B, et al. Chaperone-assisted thermostability engineering of a soluble T cell receptor using phage display. Sci Rep. 2013;3:1162 pubmed publisher
Kimura T, Tsutsumi K, Taoka M, Saito T, Masuda Suzukake M, Ishiguro K, et al. Isomerase Pin1 stimulates dephosphorylation of tau protein at cyclin-dependent kinase (Cdk5)-dependent Alzheimer phosphorylation sites. J Biol Chem. 2013;288:7968-77 pubmed publisher
Bell R, Kunuthur S, Hendry C, Bruce Hickman D, Davidson S, Yellon D. Matrix metalloproteinase inhibition protects CyPD knockout mice independently of RISK/mPTP signalling: a parallel pathway to protection. Basic Res Cardiol. 2013;108:331 pubmed publisher
Quinn M, Wojnarowicz P, Pickett A, Provencher D, Mes Masson A, Davis E, et al. FKBP10/FKBP65 expression in high-grade ovarian serous carcinoma and its association with patient outcome. Int J Oncol. 2013;42:912-20 pubmed publisher
Lin D, Zimmermann S, Stuwe T, Stuwe E, Hoelz A. Structural and functional analysis of the C-terminal domain of Nup358/RanBP2. J Mol Biol. 2013;425:1318-29 pubmed publisher
Bonora M, Bononi A, De Marchi E, Giorgi C, Lebiedzinska M, Marchi S, et al. Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition. Cell Cycle. 2013;12:674-83 pubmed publisher
Pottecher J, Guillot M, Belaidi E, Charles A, Lejay A, Gharib A, et al. Cyclosporine A normalizes mitochondrial coupling, reactive oxygen species production, and inflammation and partially restores skeletal muscle maximal oxidative capacity in experimental aortic cross-clamping. J Vasc Surg. 2013;57:1100-1108.e2 pubmed publisher
Ellsworth K, Moon I, Eckloff B, Fridley B, Jenkins G, Batzler A, et al. FKBP5 genetic variation: association with selective serotonin reuptake inhibitor treatment outcomes in major depressive disorder. Pharmacogenet Genomics. 2013;23:156-66 pubmed publisher
van de Hoef D, Bonner J, Boulianne G. FKBP14 is an essential gene that regulates Presenilin protein levels and Notch signaling in Drosophila. Development. 2013;140:810-9 pubmed publisher
van Kruchten R, Mattheij N, Saunders C, Feijge M, Swieringa F, Wolfs J, et al. Both TMEM16F-dependent and TMEM16F-independent pathways contribute to phosphatidylserine exposure in platelet apoptosis and platelet activation. Blood. 2013;121:1850-7 pubmed publisher
Payeli S, Schiene Fischer C, Steffel J, Camici G, Rozenberg I, Luscher T, et al. Cyclophilin A differentially activates monocytes and endothelial cells: role of purity, activity, and endotoxin contamination in commercial preparations. Atherosclerosis. 2008;197:564-71 pubmed
Eisenmesser E, Bosco D, Akke M, Kern D. Enzyme dynamics during catalysis. Science. 2002;295:1520-3 pubmed
Hennig L, Christner C, Kipping M, Schelbert B, Rücknagel K, Grabley S, et al. Selective inactivation of parvulin-like peptidyl-prolyl cis/trans isomerases by juglone. Biochemistry. 1998;37:5953-60 pubmed
Fischer G, Bang H, Mech C. [Determination of enzymatic catalysis for the cis-trans-isomerization of peptide binding in proline-containing peptides]. Biomed Biochim Acta. 1984;43:1101-11 pubmed
Fischer G, Bang H. The refolding of urea-denatured ribonuclease A is catalyzed by peptidyl-prolyl cis-trans isomerase. Biochim Biophys Acta. 1985;828:39-42 pubmed
Takahashi N, Hayano T, Suzuki M. Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin. Nature. 1989;337:473-5 pubmed
Fischer G, Wittmann Liebold B, Lang K, Kiefhaber T, Schmid F. Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins. Nature. 1989;337:476-8 pubmed
Harrison R, Stein R. Substrate specificities of the peptidyl prolyl cis-trans isomerase activities of cyclophilin and FK-506 binding protein: evidence for the existence of a family of distinct enzymes. Biochemistry. 1990;29:3813-6 pubmed
product information
Catalog Number :
C3805
Product Name :
Cyclophilin A human
Product Type :
PROTEINS & ENZYMES
Product Group :
Protein & Pathway Technologies
Product Description :
≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous solution
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA