product summary
company name :
MilliporeSigma
other brands :
FLUKA, Sigma-Aldrich, Roche Applied Science
product type :
antibody
product name :
Anti-β-Catenin antibody produced in rabbit
catalog :
C2206
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
common lancelet, human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - frozen section, other, western blot knockout validation, immunohistochemistry knockout validation
more info or order :
citations: 148
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1:8000; fig 5a
Sui Y, Liu Z, Park S, Thatcher S, Zhu B, Fernandez J, et al. IKKβ is a β-catenin kinase that regulates mesenchymal stem cell differentiation. JCI Insight. 2018;3: pubmed publisher
  • immunohistochemistry knockout validation; mouse; 1:500; loading ...; fig 6a
  • western blot; mouse; 1:1000; loading ...; fig s1a
Nakagawa N, Li J, Yabuno Nakagawa K, Eom T, Cowles M, Mapp T, et al. APC sets the Wnt tone necessary for cerebral cortical progenitor development. Genes Dev. 2017;31:1679-1692 pubmed publisher
  • immunohistochemistry; common lancelet; loading ...; fig 1j
Kozmikova I, Kozmik Z. Wnt/β-catenin signaling is an evolutionarily conserved determinant of chordate dorsal organizer. elife. 2020;9: pubmed publisher
  • western blot; human; 1:1000; fig 2c
Carvalho J, Fortunato I, Fonseca C, Pezzarossa A, Barbacena P, Domínguez Cejudo M, et al. Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration. elife. 2019;8: pubmed publisher
  • western blot; human; loading ...; fig 6a
Shen L, Qu X, Li H, Xu C, Wei M, Wang Q, et al. NDRG2 facilitates colorectal cancer differentiation through the regulation of Skp2-p21/p27 axis. Oncogene. 2018;37:1759-1774 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 3b
Vassilev V, Platek A, Hiver S, Enomoto H, Takeichi M. Catenins Steer Cell Migration via Stabilization of Front-Rear Polarity. Dev Cell. 2017;43:463-479.e5 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:150; loading ...; fig 4h
Wang X, Chen H, Tian R, Zhang Y, Drutskaya M, Wang C, et al. Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF. Nat Commun. 2017;8:14091 pubmed publisher
  • immunocytochemistry; rat; loading ...
Van Itallie C, Tietgens A, Anderson J. Visualizing the dynamic coupling of claudin strands to the actin cytoskeleton through ZO-1. Mol Biol Cell. 2017;28:524-534 pubmed publisher
  • other; human; loading ...; fig 3
Su W, Kowalczyk A. The VE-cadherin cytoplasmic domain undergoes proteolytic processing during endocytosis. Mol Biol Cell. 2017;28:76-84 pubmed publisher
  • chromatin immunoprecipitation; human; fig 2
  • western blot; human; fig 1
Lutgen V, Narasipura S, Sharma A, Min S, Al Harthi L. β-Catenin signaling positively regulates glutamate uptake and metabolism in astrocytes. J Neuroinflammation. 2016;13:242 pubmed publisher
  • immunocytochemistry; mouse; 1:400; fig 2b
  • western blot; mouse; 1:2000; fig 3d
Wegwitz F, Lenfert E, Gerstel D, von Ehrenstein L, Einhoff J, Schmidt G, et al. CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo. Oncotarget. 2016;7:63730-63746 pubmed publisher
  • immunocytochemistry; human; 1:400; fig 1
Dorland Y, Malinova T, van Stalborch A, Grieve A, van Geemen D, Jansen N, et al. The F-BAR protein pacsin2 inhibits asymmetric VE-cadherin internalization from tensile adherens junctions. Nat Commun. 2016;7:12210 pubmed publisher
  • immunocytochemistry; human; fig 1
Marcos Ramiro B, García Weber D, Barroso S, Feito J, Ortega M, Cernuda Morollón E, et al. RhoB controls endothelial barrier recovery by inhibiting Rac1 trafficking to the cell border. J Cell Biol. 2016;213:385-402 pubmed publisher
  • western blot; mouse; fig 4
Chatterjee I, Baruah J, Lurie E, Wary K. Endothelial lipid phosphate phosphatase-3 deficiency that disrupts the endothelial barrier function is a modifier of cardiovascular development. Cardiovasc Res. 2016;111:105-18 pubmed publisher
  • immunocytochemistry; mouse; 1:500; fig 4
  • western blot; mouse; 1:10,000; fig 4
Guerrera D, Shah J, Vasileva E, Sluysmans S, Méan I, Jond L, et al. PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins. J Biol Chem. 2016;291:11016-29 pubmed publisher
  • immunocytochemistry; human; 1:600; fig 2
Wu J, Ivanov A, Fisher P, Fu Z. Polo-like kinase 1 induces epithelial-to-mesenchymal transition and promotes epithelial cell motility by activating CRAF/ERK signaling. elife. 2016;5: pubmed publisher
  • immunoprecipitation; mouse; fig 6a
  • western blot; mouse; fig 4a
Lee S, Shatadal S, Griep A. Dlg-1 Interacts With and Regulates the Activities of Fibroblast Growth Factor Receptors and EphA2 in the Mouse Lens. Invest Ophthalmol Vis Sci. 2016;57:707-18 pubmed publisher
  • western blot; human; fig 8
Gawron D, Ndah E, Gevaert K, Van Damme P. Positional proteomics reveals differences in N-terminal proteoform stability. Mol Syst Biol. 2016;12:858 pubmed publisher
  • immunocytochemistry; mouse; fig 5
Iyer S, Chou F, Wang R, Chiu H, Raju V, Little M, et al. Crim1 has cell-autonomous and paracrine roles during embryonic heart development. Sci Rep. 2016;6:19832 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 9b
Wymeersch F, Huang Y, Blin G, Cambray N, Wilkie R, Wong F, et al. Position-dependent plasticity of distinct progenitor types in the primitive streak. elife. 2016;5:e10042 pubmed publisher
  • immunocytochemistry; mouse; fig 2
Kitayama M, Mizutani K, Maruoka M, Mandai K, Sakakibara S, Ueda Y, et al. A Novel Nectin-mediated Cell Adhesion Apparatus That Is Implicated in Prolactin Receptor Signaling for Mammary Gland Development. J Biol Chem. 2016;291:5817-31 pubmed publisher
  • immunocytochemistry; human; 1:300; loading ...; fig 2B; S1C
  • western blot; human; 1:4000; loading ...; fig 2A
Pai P, Rachagani S, Lakshmanan I, Macha M, Sheinin Y, Smith L, et al. The canonical Wnt pathway regulates the metastasis-promoting mucin MUC4 in pancreatic ductal adenocarcinoma. Mol Oncol. 2016;10:224-39 pubmed publisher
Robinson K, Narasipura S, Wallace J, Ritz E, Al Harthi L. β-Catenin and TCFs/LEF signaling discordantly regulate IL-6 expression in astrocytes. Cell Commun Signal. 2020;18:93 pubmed publisher
Ardid Ruiz A, Harazin A, Barna L, Walter F, Bladé C, Suarez M, et al. The effects of Vitis vinifera L. phenolic compounds on a blood-brain barrier culture model: Expression of leptin receptors and protection against cytokine-induced damage. J Ethnopharmacol. 2020;247:112253 pubmed publisher
Shigeoka T, Koppers M, Wong H, Lin J, Cagnetta R, Dwivedy A, et al. On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons. Cell Rep. 2019;29:3605-3619.e10 pubmed publisher
Carneiro P, Moreira A, Figueiredo J, Barros R, Oliveira P, Fernandes M, et al. S100P is a molecular determinant of E-cadherin function in gastric cancer. Cell Commun Signal. 2019;17:155 pubmed publisher
Nano M, Gemble S, Simon A, Pennetier C, Fraisier V, Marthiens V, et al. Cell-Cycle Asynchrony Generates DNA Damage at Mitotic Entry in Polyploid Cells. Curr Biol. 2019;29:3937-3945.e7 pubmed publisher
Basu S, Cheriyamundath S, Gavert N, Brabletz T, Haase G, Ben Ze ev A. Increased expression of cathepsin D is required for L1-mediated colon cancer progression. Oncotarget. 2019;10:5217-5228 pubmed publisher
Tuladhar R, Yeu Y, Tyler Piazza J, Tan Z, Rene Clemenceau J, Wu X, et al. CRISPR-Cas9-based mutagenesis frequently provokes on-target mRNA misregulation. Nat Commun. 2019;10:4056 pubmed publisher
Heuzé M, Sankara Narayana G, D Alessandro J, Cellerin V, Dang T, Williams D, et al. Myosin II isoforms play distinct roles in adherens junction biogenesis. elife. 2019;8: pubmed publisher
Littler S, Sloss O, Geary B, Pierce A, Whetton A, Taylor S. Oncogenic MYC amplifies mitotic perturbations. Open Biol. 2019;9:190136 pubmed publisher
Mirfazeli E, Arefian E, Nadri S, Rezazadeh Valojerdi R, Kehtari M, Zeynali B. DKK1 expression is suppressed by miR-9 during induced dopaminergic differentiation of human trabecular meshwork mesenchymal stem cells. Neurosci Lett. 2019;707:134250 pubmed publisher
Gravotta D, Perez Bay A, Jonker C, Zager P, Benedicto I, Schreiner R, et al. Clathrin and clathrin adaptor AP-1 control apical trafficking of megalin in the biosynthetic and recycling routes. Mol Biol Cell. 2019;30:1716-1728 pubmed publisher
Redmond S, Figueres Oñate M, Obernier K, Nascimento M, Parraguez J, López Mascaraque L, et al. Development of Ependymal and Postnatal Neural Stem Cells and Their Origin from a Common Embryonic Progenitor. Cell Rep. 2019;27:429-441.e3 pubmed publisher
Rauner M, Baschant U, Roetto A, Pellegrino R, Rother S, Salbach Hirsch J, et al. Transferrin receptor 2 controls bone mass and pathological bone formation via BMP and Wnt signaling. Nat Metab. 2019;1:111-124 pubmed publisher
Hartl M, Glasauer S, Gufler S, Raffeiner A, Puglisi K, Breuker K, et al. Differential regulation of myc homologs by Wnt/β-Catenin signaling in the early metazoan Hydra. FEBS J. 2019;286:2295-2310 pubmed publisher
Zhang J, He L, Yang Z, Li L, Cai W. Lithium chloride promotes proliferation of neural stem cells in vitro, possibly by triggering the Wnt signaling pathway. Anim Cells Syst (Seoul). 2019;23:32-41 pubmed publisher
Lashhab R, Rumley A, Arutyunov D, Rizvi M, You C, Dimke H, et al. The kidney anion exchanger 1 affects tight junction properties via claudin-4. Sci Rep. 2019;9:3099 pubmed publisher
Wang M, Li Y, Xiao G, Zheng X, Wang J, Xu C, et al. H19 regulation of oestrogen induction of symmetric division is achieved by antagonizing Let-7c in breast cancer stem-like cells. Cell Prolif. 2019;52:e12534 pubmed publisher
Onai T. Canonical Wnt/β-catenin and Notch signaling regulate animal/vegetal axial patterning in the cephalochordate amphioxus. Evol Dev. 2019;21:31-43 pubmed publisher
Duan S, Huang W, Liu X, Liu X, Chen N, Xu Q, et al. IMPDH2 promotes colorectal cancer progression through activation of the PI3K/AKT/mTOR and PI3K/AKT/FOXO1 signaling pathways. J Exp Clin Cancer Res. 2018;37:304 pubmed publisher
Yan L, Chen J, Zhu X, Sun J, Wu X, Shen W, et al. Maternal Huluwa dictates the embryonic body axis through β-catenin in vertebrates. Science. 2018;362: pubmed publisher
Hoang Minh L, Siebzehnrubl F, Yang C, Suzuki Hatano S, Dajac K, Loche T, et al. Infiltrative and drug-resistant slow-cycling cells support metabolic heterogeneity in glioblastoma. EMBO J. 2018;37: pubmed publisher
Shawky J, Balakrishnan U, Stuckenholz C, Davidson L. Multiscale analysis of architecture, cell size and the cell cortex reveals cortical F-actin density and composition are major contributors to mechanical properties during convergent extension. Development. 2018;145: pubmed publisher
Han Y, Kim M, Lee K. Berberine derivative, Q8, stimulates osteogenic differentiation. Biochem Biophys Res Commun. 2018;504:340-345 pubmed publisher
Sun J, Yan L, Shen W, Meng A. Maternal Ybx1 safeguards zebrafish oocyte maturation and maternal-to-zygotic transition by repressing global translation. Development. 2018;145: pubmed publisher
Yu Z, Jiang K, Xu Z, Huang H, Qian N, Lu Z, et al. Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration. Cell Stem Cell. 2018;23:487-500.e6 pubmed publisher
Lin J, Yue Z. Coupling of apical-basal polarity and planar cell polarity to interpret the Wnt signaling gradient in feather development. Development. 2018;145: pubmed publisher
Yuan T, Wang S, Hu C, Wu Y, Liang D, Li L, et al. Low-density lipoprotein receptor-related protein 6 regulates alternative pre-mRNA splicing. J Cell Mol Med. 2018;22:4653-4663 pubmed publisher
Salinas Saavedra M, Rock A, Martindale M. Germ layer-specific regulation of cell polarity and adhesion gives insight into the evolution of mesoderm. elife. 2018;7: pubmed publisher
Oldani G, Peloso A, Vijgen S, Wilson E, Slits F, Gex Q, et al. Chimeric liver transplantation reveals interspecific graft remodelling. J Hepatol. 2018;69:1025-1036 pubmed publisher
Kam C, Dubash A, Magistrati E, Polo S, Satchell K, Sheikh F, et al. Desmoplakin maintains gap junctions by inhibiting Ras/MAPK and lysosomal degradation of connexin-43. J Cell Biol. 2018;217:3219-3235 pubmed publisher
Žídek R, Machon O, Kozmik Z. Wnt/β-catenin signalling is necessary for gut differentiation in a marine annelid, Platynereis dumerilii. Evodevo. 2018;9:14 pubmed publisher
Pan J, Xiong L, Zhao K, Zeng P, Wang B, Tang F, et al. YAP promotes osteogenesis and suppresses adipogenic differentiation by regulating β-catenin signaling. Bone Res. 2018;6:18 pubmed publisher
Yeh W, Chiang H, Rees H, Edge A, Liu D. In vivo base editing of post-mitotic sensory cells. Nat Commun. 2018;9:2184 pubmed publisher
Zhang P, Schaefer Klein J, Cheville J, Vasmatzis G, Kovtun I. Frequently rearranged and overexpressed δ-catenin is responsible for low sensitivity of prostate cancer cells to androgen receptor and β-catenin antagonists. Oncotarget. 2018;9:24428-24442 pubmed publisher
Hönig E, Ringer K, Dewes J, von Mach T, Kamm N, Kreitzer G, et al. Galectin-3 modulates the polarized surface delivery of ?1-integrin in epithelial cells. J Cell Sci. 2018;131: pubmed publisher
Vanarsdall A, Pritchard S, Wisner T, Liu J, Jardetzky T, Johnson D. CD147 Promotes Entry of Pentamer-Expressing Human Cytomegalovirus into Epithelial and Endothelial Cells. MBio. 2018;9: pubmed publisher
Juan T, Liu K, Kuo C, Yang M, Chu Y, Yang J, et al. Tetrandrine suppresses adhesion, migration and invasion of human colon cancer SW620 cells via inhibition of nuclear factor-κB, matrix metalloproteinase-2 and matrix metalloproteinase-9 signaling pathways. Oncol Lett. 2018;15:7716-7724 pubmed publisher
Wang F, Liu Z, Park S, Gwag T, Lu W, Ma M, et al. Myeloid ?-Catenin Deficiency Exacerbates Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice. Arterioscler Thromb Vasc Biol. 2018;38:1468-1478 pubmed publisher
Forbes T, Howden S, Lawlor K, Phipson B, Maksimovic J, Hale L, et al. Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms. Am J Hum Genet. 2018;102:816-831 pubmed publisher
Chu C, Xiang B, Ossipova O, Ioannou A, Sokol S. The Ajuba family protein Wtip regulates actomyosin contractility during vertebrate neural tube closure. J Cell Sci. 2018;131: pubmed publisher
Cheng D, Yan X, Qiu G, Zhang J, Wang H, Feng T, et al. Contraction of basal filopodia controls periodic feather branching via Notch and FGF signaling. Nat Commun. 2018;9:1345 pubmed publisher
Swarup A, Bell B, Du J, Han J, Soto J, Abel E, et al. Deletion of GLUT1 in mouse lens epithelium leads to cataract formation. Exp Eye Res. 2018;172:45-53 pubmed publisher
Elisha Y, Kalchenko V, Kuznetsov Y, Geiger B. Dual role of E-cadherin in the regulation of invasive collective migration of mammary carcinoma cells. Sci Rep. 2018;8:4986 pubmed publisher
Nekrasova O, Harmon R, Broussard J, Koetsier J, Godsel L, Fitz G, et al. Desmosomal cadherin association with Tctex-1 and cortactin-Arp2/3 drives perijunctional actin polymerization to promote keratinocyte delamination. Nat Commun. 2018;9:1053 pubmed publisher
Nascimento M, Sorokin L, Coelho Sampaio T. Fractone Bulbs Derive from Ependymal Cells and Their Laminin Composition Influence the Stem Cell Niche in the Subventricular Zone. J Neurosci. 2018;38:3880-3889 pubmed publisher
Tsai K, Lo Y, Liu H, Yeh C, Chen Y, Hsu C, et al. Linc00659, a long noncoding RNA, acts as novel oncogene in regulating cancer cell growth in colorectal cancer. Mol Cancer. 2018;17:72 pubmed publisher
Colomer C, Margalef P, Gonzalez J, Vert A, Bigas A, Espinosa L. IKKα is required in the intestinal epithelial cells for tumour stemness. Br J Cancer. 2018;118:839-846 pubmed publisher
Ray A, Katoch P, Jain N, Mehta P. Dileucine-like motifs in the C-terminal tail of connexin32 control its endocytosis and assembly into gap junctions. J Cell Sci. 2018;131: pubmed publisher
Hříbková H, Grabiec M, Klemová D, Slaninova I, Sun Y. Calcium signaling mediates five types of cell morphological changes to form neural rosettes. J Cell Sci. 2018;131: pubmed publisher
Wang W, Hu Y, Wang X, Wang Q, Deng H. ROS-Mediated 15-Hydroxyprostaglandin Dehydrogenase Degradation via Cysteine Oxidation Promotes NAD+-Mediated Epithelial-Mesenchymal Transition. Cell Chem Biol. 2018;25:255-261.e4 pubmed publisher
Junghans D, Herzog S. Cnn3 regulates neural tube morphogenesis and neuronal stem cell properties. FEBS J. 2018;285:325-338 pubmed publisher
Bozzo M, Pergner J, Kozmik Z, Kozmikova I. Novel polyclonal antibodies as a useful tool for expression studies in amphioxus embryos. Int J Dev Biol. 2017;61:793-800 pubmed publisher
Mii Y, Yamamoto T, Takada R, Mizumoto S, Matsuyama M, Yamada S, et al. Roles of two types of heparan sulfate clusters in Wnt distribution and signaling in Xenopus. Nat Commun. 2017;8:1973 pubmed publisher
Ito S, Okuda S, Abe M, Fujimoto M, Onuki T, Nishimura T, et al. Induced cortical tension restores functional junctions in adhesion-defective carcinoma cells. Nat Commun. 2017;8:1834 pubmed publisher
Mack J, Mosqueiro T, Archer B, Jones W, Sunshine H, Faas G, et al. NOTCH1 is a mechanosensor in adult arteries. Nat Commun. 2017;8:1620 pubmed publisher
Short S, Kondo J, Smalley Freed W, Takeda H, Dohn M, Powell A, et al. p120-Catenin is an obligate haploinsufficient tumor suppressor in intestinal neoplasia. J Clin Invest. 2017;127:4462-4476 pubmed publisher
Ridge L, Mitchell K, Al Anbaki A, Shaikh Qureshi W, Stephen L, Tenin G, et al. Non-muscle myosin IIB (Myh10) is required for epicardial function and coronary vessel formation during mammalian development. PLoS Genet. 2017;13:e1007068 pubmed publisher
Cao J, Wang J, Jackman C, Cox A, Trembley M, Balowski J, et al. Tension Creates an Endoreplication Wavefront that Leads Regeneration of Epicardial Tissue. Dev Cell. 2017;42:600-615.e4 pubmed publisher
Fujitani M, Sato R, Yamashita T. Loss of p73 in ependymal cells during the perinatal period leads to aqueductal stenosis. Sci Rep. 2017;7:12007 pubmed publisher
NAJOR N, Fitz G, Koetsier J, Godsel L, Albrecht L, Harmon R, et al. Epidermal Growth Factor Receptor neddylation is regulated by a desmosomal-COP9 (Constitutive Photomorphogenesis 9) signalosome complex. elife. 2017;6: pubmed publisher
Lázaro Diéguez F, Müsch A. Cell-cell adhesion accounts for the different orientation of columnar and hepatocytic cell divisions. J Cell Biol. 2017;216:3847-3859 pubmed publisher
Wong H, Lin J, Ströhl F, Roque C, Cioni J, Cagnetta R, et al. RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo. Neuron. 2017;95:852-868.e8 pubmed publisher
Trease A, Capuccino J, Contreras J, Harris A, Sorgen P. Intramolecular signaling in a cardiac connexin: Role of cytoplasmic domain dimerization. J Mol Cell Cardiol. 2017;111:69-80 pubmed publisher
Cerrone M, Montnach J, Lin X, Zhao Y, Zhang M, Agullo Pascual E, et al. Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm. Nat Commun. 2017;8:106 pubmed publisher
Hamann J, Surcel A, Chen R, Teragawa C, Albeck J, Robinson D, et al. Entosis Is Induced by Glucose Starvation. Cell Rep. 2017;20:201-210 pubmed publisher
Cirelli E, De Domenico E, Botti F, Massoud R, Geremia R, Grimaldi P. Effect Of Microgravity On Aromatase Expression In Sertoli Cells. Sci Rep. 2017;7:3469 pubmed publisher
Yu C, Narasipura S, Richards M, Hu X, Yamamoto B, Al Harthi L. HIV and drug abuse mediate astrocyte senescence in a β-catenin-dependent manner leading to neuronal toxicity. Aging Cell. 2017;16:956-965 pubmed publisher
Zhang P, Li J, Song Y, Wang X. MiR-129-5p Inhibits Proliferation and Invasion of Chondrosarcoma Cells by Regulating SOX4/Wnt/β-Catenin Signaling Pathway. Cell Physiol Biochem. 2017;42:242-253 pubmed publisher
Ball C, Oppel F, Ehrenberg K, Dubash T, Dieter S, Hoffmann C, et al. Succession of transiently active tumor-initiating cell clones in human pancreatic cancer xenografts. EMBO Mol Med. 2017;9:918-932 pubmed publisher
Melsens E, De Vlieghere E, Descamps B, Vanhove C, De Wever O, Ceelen W, et al. Improved xenograft efficiency of esophageal adenocarcinoma cell lines through in vivo selection. Oncol Rep. 2017;38:71-81 pubmed publisher
Nag J, Kancharla A, Maoz M, Turm H, Agranovich D, Gupta C, et al. Low-density lipoprotein receptor-related protein 6 is a novel coreceptor of protease-activated receptor-2 in the dynamics of cancer-associated ?-catenin stabilization. Oncotarget. 2017;8:38650-38667 pubmed publisher
Chaverra M, George L, Mergy M, Waller H, Kujawa K, Murnion C, et al. The familial dysautonomia disease gene IKBKAP is required in the developing and adult mouse central nervous system. Dis Model Mech. 2017;10:605-618 pubmed publisher
Schall K, Thornton M, Isani M, Holoyda K, Hou X, Lien C, et al. Short bowel syndrome results in increased gene expression associated with proliferation, inflammation, bile acid synthesis and immune system activation: RNA sequencing a zebrafish SBS model. BMC Genomics. 2017;18:23 pubmed publisher
Li A, Figueroa S, Jiang T, Wu P, Widelitz R, Nie Q, et al. Diverse feather shape evolution enabled by coupling anisotropic signalling modules with self-organizing branching programme. Nat Commun. 2017;8:ncomms14139 pubmed publisher
Huang G, Ge G, Izzi V, Greenspan D. α3 Chains of type V collagen regulate breast tumour growth via glypican-1. Nat Commun. 2017;8:14351 pubmed publisher
Mirzadeh Z, Kusne Y, Duran Moreno M, Cabrales E, Gil Perotin S, Ortiz C, et al. Bi- and uniciliated ependymal cells define continuous floor-plate-derived tanycytic territories. Nat Commun. 2017;8:13759 pubmed publisher
Luo G, Luo W, Sun X, Lin J, Wang M, Zhang Y, et al. MicroRNA?21 promotes migration and invasion of glioma cells via activation of Sox2 and ??catenin signaling. Mol Med Rep. 2017;15:187-193 pubmed publisher
Emon S, Uslu S, Aydinlar E, Irban A, Ince U, Orakdogen M, et al. Effects of Ozone on Spinal Cord Recovery via the Wnt/ Β-Catenin Pathway Following Spinal Cord Injury in Rats. Turk Neurosurg. 2017;27:946-951 pubmed publisher
Jenkins E, Caputo M, Angelini G, Ghorbel M. Chronic hypoxia down-regulates tight junction protein ZO-2 expression in children with cyanotic congenital heart defect. ESC Heart Fail. 2016;3:131-137 pubmed
Kim H, Jang S, Lee S, Kim Y, Ohn Y, Brinkmann R, et al. Retinal Pigment Epithelium Responses to Selective Retina Therapy in Mouse Eyes. Invest Ophthalmol Vis Sci. 2016;57:3486-95 pubmed publisher
Gu Y, Wang Q, Guo K, Qin W, Liao W, Wang S, et al. TUSC3 promotes colorectal cancer progression and epithelial-mesenchymal transition (EMT) through WNT/β-catenin and MAPK signalling. J Pathol. 2016;239:60-71 pubmed publisher
Patil S, Gokulnath P, Bashir M, Shwetha S, Jaiswal J, Shastry A, et al. Insulin-like growth factor binding protein-2 regulates β-catenin signaling pathway in glioma cells and contributes to poor patient prognosis. Neuro Oncol. 2016;18:1487-1497 pubmed
Leclère L, Bause M, Sinigaglia C, Steger J, Rentzsch F. Development of the aboral domain in Nematostella requires ?-catenin and the opposing activities of Six3/6 and Frizzled5/8. Development. 2016;143:1766-77 pubmed publisher
Eno C, SOLANKI B, Pelegri F. aura (mid1ip1l) regulates the cytoskeleton at the zebrafish egg-to-embryo transition. Development. 2016;143:1585-99 pubmed publisher
Aratyn Schaus Y, Pasqualini F, Yuan H, McCain M, Ye G, Sheehy S, et al. Coupling primary and stem cell-derived cardiomyocytes in an in vitro model of cardiac cell therapy. J Cell Biol. 2016;212:389-97 pubmed publisher
Hamilton P, Sun Y, Henry J. Lens regeneration from the cornea requires suppression of Wnt/β-catenin signaling. Exp Eye Res. 2016;145:206-215 pubmed publisher
Li J, Chatzeli L, Panousopoulou E, Tucker A, Green J. Epithelial stratification and placode invagination are separable functions in early morphogenesis of the molar tooth. Development. 2016;143:670-81 pubmed publisher
Loubat Casanovas J, Peña R, Gonzàlez N, Alba Castellón L, Rosell S, Francí C, et al. Snail1 is required for the maintenance of the pancreatic acinar phenotype. Oncotarget. 2016;7:4468-82 pubmed publisher
Felber K, Elks P, Lecca M, Roehl H. Expression of osterix Is Regulated by FGF and Wnt/β-Catenin Signalling during Osteoblast Differentiation. PLoS ONE. 2015;10:e0144982 pubmed publisher
Kant S, Krusche C, Gaertner A, Milting H, Leube R. Loss of plakoglobin immunoreactivity in intercalated discs in arrhythmogenic right ventricular cardiomyopathy: protein mislocalization versus epitope masking. Cardiovasc Res. 2016;109:260-71 pubmed publisher
Zeng X, Montoute M, Bee T, Lin H, Kallal L, Liu Y, et al. A High-Content Imaging Screen for Cellular Regulators of β-Catenin Protein Abundance. J Biomol Screen. 2016;21:260-8 pubmed publisher
Xu Z, Wang W, Jiang K, Yu Z, Huang H, Wang F, et al. Embryonic attenuated Wnt/β-catenin signaling defines niche location and long-term stem cell fate in hair follicle. elife. 2015;4:e10567 pubmed publisher
Kessler M, Hoffmann K, Brinkmann V, Thieck O, Jackisch S, Toelle B, et al. The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids. Nat Commun. 2015;6:8989 pubmed publisher
Takata N, Sakakura E, Sasai Y. Activation of Wnt/ß-catenin signaling in ESC promotes rostral forebrain differentiation in vitro. In Vitro Cell Dev Biol Anim. 2016;52:374-82 pubmed publisher
Aupperlee M, Zhao Y, Tan Y, Zhu Y, Langohr I, Kirk E, et al. Puberty-specific promotion of mammary tumorigenesis by a high animal fat diet. Breast Cancer Res. 2015;17:138 pubmed publisher
Thirumangalathu S, Barlow L. β-Catenin signaling regulates temporally discrete phases of anterior taste bud development. Development. 2015;142:4309-17 pubmed publisher
Buchert M, Rohde F, Eissmann M, Tebbutt N, Williams B, Tan C, et al. A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations. Dis Model Mech. 2015;8:1361-73 pubmed publisher
Yesildag B, Bock T, Herrmanns K, Wollscheid B, Stoffel M. Kin of IRRE-like Protein 2 Is a Phosphorylated Glycoprotein That Regulates Basal Insulin Secretion. J Biol Chem. 2015;290:25891-906 pubmed publisher
Ohata S, Herranz Pérez V, Nakatani J, Boletta A, García Verdugo J, Álvarez Buylla A. Mechanosensory Genes Pkd1 and Pkd2 Contribute to the Planar Polarization of Brain Ventricular Epithelium. J Neurosci. 2015;35:11153-68 pubmed publisher
Arensman M, Nguyen P, Kershaw K, Lay A, Ostertag Hill C, Sherman M, et al. Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer. Mol Cancer Res. 2015;13:1509-19 pubmed publisher
Hamilton K, Chatterji P, Lundsmith E, Andres S, Giroux V, Hicks P, et al. Loss of Stromal IMP1 Promotes a Tumorigenic Microenvironment in the Colon. Mol Cancer Res. 2015;13:1478-86 pubmed publisher
Biyajima K, Kakizaki F, Shen X, Mori K, Sugai M, Taketo M, et al. Id2 deletion attenuates Apc-deficient ileal tumor formation. Biol Open. 2015;4:993-1001 pubmed publisher
Kistler W, Baas D, Lemeille S, Paschaki M, Seguín Estévez Q, Barras E, et al. RFX2 Is a Major Transcriptional Regulator of Spermiogenesis. PLoS Genet. 2015;11:e1005368 pubmed publisher
Li Villarreal N, Forbes M, Loza A, Chen J, Ma T, Helde K, et al. Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis. Development. 2015;142:2704-18 pubmed publisher
Chang Y, Su Y, Hsiao M, Wei K, Lin W, Liang C, et al. Diverse Targets of β-Catenin during the Epithelial-Mesenchymal Transition Define Cancer Stem Cells and Predict Disease Relapse. Cancer Res. 2015;75:3398-410 pubmed publisher
Tan C, Hirokawa Y, Burgess A. Analysis of Wnt signalling dynamics during colon crypt development in 3D culture. Sci Rep. 2015;5:11036 pubmed publisher
Su Y, Chang Y, Lin W, Liang C, Lee J. An aberrant nuclear localization of E-cadherin is a potent inhibitor of Wnt/β-catenin-elicited promotion of the cancer stem cell phenotype. Oncogenesis. 2015;4:e157 pubmed publisher
Van Itallie C, Tietgens A, Krystofiak E, Kachar B, Anderson J. A complex of ZO-1 and the BAR-domain protein TOCA-1 regulates actin assembly at the tight junction. Mol Biol Cell. 2015;26:2769-87 pubmed publisher
Gay M, Valenta T, Herr P, Paratore Hari L, Basler K, Sommer L. Distinct adhesion-independent functions of β-catenin control stage-specific sensory neurogenesis and proliferation. BMC Biol. 2015;13:24 pubmed publisher
Bol G, Vesuna F, Xie M, Zeng J, Aziz K, Gandhi N, et al. Targeting DDX3 with a small molecule inhibitor for lung cancer therapy. EMBO Mol Med. 2015;7:648-69 pubmed publisher
Gendronneau G, Sanii S, Dang T, Deshayes F, Delacour D, Pichard E, et al. Overexpression of galectin-7 in mouse epidermis leads to loss of cell junctions and defective skin repair. PLoS ONE. 2015;10:e0119031 pubmed publisher
Albrecht L, Zhang L, Shabanowitz J, Purevjav E, Towbin J, Hunt D, et al. GSK3- and PRMT-1-dependent modifications of desmoplakin control desmoplakin-cytoskeleton dynamics. J Cell Biol. 2015;208:597-612 pubmed publisher
Bikkavilli R, Avasarala S, Van Scoyk M, Arcaroli J, Brzezinski C, Zhang W, et al. Wnt7a is a novel inducer of β-catenin-independent tumor-suppressive cellular senescence in lung cancer. Oncogene. 2015;34:5317-28 pubmed publisher
Desmurs M, Foti M, Raemy E, Vaz F, Martinou J, Bairoch A, et al. C11orf83, a mitochondrial cardiolipin-binding protein involved in bc1 complex assembly and supercomplex stabilization. Mol Cell Biol. 2015;35:1139-56 pubmed publisher
Wilkinson L, Neal C, Singh R, Sparrow D, Kurniawan N, Ju A, et al. Renal developmental defects resulting from in utero hypoxia are associated with suppression of ureteric β-catenin signaling. Kidney Int. 2015;87:975-83 pubmed publisher
Burczyk M, Burkhalter M, Blätte T, Matysik S, Caron M, BARAK L, et al. Phenotypic regulation of the sphingosine 1-phosphate receptor miles apart by G protein-coupled receptor kinase 2. Biochemistry. 2015;54:765-75 pubmed publisher
López Arribillaga E, Rodilla V, Pellegrinet L, Guiu J, Iglesias M, Roman A, et al. Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch. Development. 2015;142:41-50 pubmed publisher
Kim K, Ossipova O, Sokol S. Neural crest specification by inhibition of the ROCK/Myosin II pathway. Stem Cells. 2015;33:674-85 pubmed publisher
Uehara Y, Inoue M, Fukuda K, Yamakoshi H, Hosoi Y, Kanda H, et al. Inhibition of β-catenin and STAT3 with a curcumin analog suppresses gastric carcinogenesis in vivo. Gastric Cancer. 2015;18:774-83 pubmed publisher
Ali J, Lagasse B, Minuk A, Love A, Moraya A, Lam L, et al. Differential cellular responses induced by dorsomorphin and LDN-193189 in chemotherapy-sensitive and chemotherapy-resistant human epithelial ovarian cancer cells. Int J Cancer. 2015;136:E455-69 pubmed publisher
Yanagisawa M, Anastasiadis P. p120 catenin is essential for mesenchymal cadherin-mediated regulation of cell motility and invasiveness. J Cell Biol. 2006;174:1087-96 pubmed
Davis M, Ireton R, Reynolds A. A core function for p120-catenin in cadherin turnover. J Cell Biol. 2003;163:525-34 pubmed
Huen A, Park J, Godsel L, Chen X, Bannon L, Amargo E, et al. Intermediate filament-membrane attachments function synergistically with actin-dependent contacts to regulate intercellular adhesive strength. J Cell Biol. 2002;159:1005-17 pubmed
Ireton R, Davis M, van Hengel J, Mariner D, Barnes K, Thoreson M, et al. A novel role for p120 catenin in E-cadherin function. J Cell Biol. 2002;159:465-76 pubmed
Wittchen E, Haskins J, Stevenson B. Exogenous expression of the amino-terminal half of the tight junction protein ZO-3 perturbs junctional complex assembly. J Cell Biol. 2000;151:825-36 pubmed
Thoreson M, Anastasiadis P, Daniel J, Ireton R, Wheelock M, Johnson K, et al. Selective uncoupling of p120(ctn) from E-cadherin disrupts strong adhesion. J Cell Biol. 2000;148:189-202 pubmed
product information
Product No. :
C2206
Product Name :
Anti-β-Catenin antibody produced in rabbit
Host :
rabbit
Conjugate :
unconjugated
Antibody Type :
polyclonal
Applications/Description :
Suitable for dot blot using the immunogen and related peptides conjugated to BSA; western blot: 1:4,000 using cultured MDBK cells; immunohistochemistry: 1:2,000 using bovine kidney frozen sections; immunocytochemistry: 1:2,000 using cultured MDBK cells
Species Reactivity :
several mammalian species
Storage :
Store at -20°C
more info or order :
company information
MilliporeSigma
PO Box 14508
St. Louis, MO 63178
https://www.sigmaaldrich.com
1-800-325-3010
headquarters: USA