Owolabi O, Omogbai E. Evaluation of the potassium channel activator levcromakalim (BRL38227) on the lipid profile, electrolytes and blood glucose levels of streptozotocin-diabetic rats. J Diabetes. 2013;5:88-94 pubmed publisher

Gade A, Kang M, Akbarali H. Hydrogen sulfide as an allosteric modulator of ATP-sensitive potassium channels in colonic inflammation. Mol Pharmacol. 2013;83:294-306 pubmed publisher

Scallan J, Wolpers J, Davis M. Constriction of isolated collecting lymphatic vessels in response to acute increases in downstream pressure. J Physiol. 2013;591:443-59 pubmed publisher

Ponnoth D, Nayeem M, Tilley S, Ledent C, Jamal Mustafa S. CYP-epoxygenases contribute to A2A receptor-mediated aortic relaxation via sarcolemmal KATP channels. Am J Physiol Regul Integr Comp Physiol. 2012;303:R1003-10 pubmed publisher

Yunoki M, Nakahara T, Moriuchi H, Sakamoto K, Ishii K. The relaxant action of nicorandil in bovine tracheal smooth muscle. Pharmacology. 2012;89:327-32 pubmed publisher

He X, Goyal R. CaMKII inhibition hyperpolarizes membrane and blocks nitrergic IJP by closing a Cl(-) conductance in intestinal smooth muscle. Am J Physiol Gastrointest Liver Physiol. 2012;303:G240-6 pubmed publisher

Gurpinar T, Gok S. Vasodilator effects of cromakalim and HA 1077 in diabetic rat aorta. Swiss Med Wkly. 2012;142:w13558 pubmed publisher

Tsounapi P, Saito M, Dimitriadis F, Kitatani K, Kinoshita Y, Shomori K, et al. The role of K ATP channels on ischemia-reperfusion injury in the rat testis. Life Sci. 2012;90:649-56 pubmed publisher

Kinoshita H, Matsuda N, Iranami H, Ogawa K, Hatakeyama N, Azma T, et al. Isoflurane pretreatment preserves adenosine triphosphate-sensitive K(+) channel function in the human artery exposed to oxidative stress caused by high glucose levels. Anesth Analg. 2012;115:54-61 pubmed publisher

Ohmasa F, Saito M, Oiwa H, Tsounapi P, Shomori K, Kitatani K, et al. Pharmacological preconditioning of ATP-sensitive potassium channel openers on acute urinary retention-induced bladder dysfunction in the rat. BJU Int. 2012;110:E245-52 pubmed publisher

Budni J, Freitas A, Binfaré R, Rodrigues A. Role of potassium channels in the antidepressant-like effect of folic acid in the forced swimming test in mice. Pharmacol Biochem Behav. 2012;101:148-54 pubmed publisher

Provencher M, Houde V, Brochu M, St Louis J. Mineralocorticoids participate in the reduced vascular reactivity of pregnant rats. Am J Physiol Heart Circ Physiol. 2012;302:H1195-201 pubmed publisher

Ploug K, Amrutkar D, Baun M, Ramachandran R, Iversen A, Lund T, et al. K(ATP) channel openers in the trigeminovascular system. Cephalalgia. 2012;32:55-65 pubmed publisher

Graciotti L, Becker J, Granata A, Procopio A, Tessarollo L, Fulgenzi G. Dystrophin is required for the normal function of the cardio-protective K(ATP) channel in cardiomyocytes. PLoS ONE. 2011;6:e27034 pubmed publisher

Wu X, Liu W, Liu Y, Huang Z, Zhang Y, Song X. Reopening of ATP-sensitive potassium channels reduces neuropathic pain and regulates astroglial gap junctions in the rat spinal cord. Pain. 2011;152:2605-15 pubmed publisher

Zhang X, Zhao J, Kang S, Yi M, You S, Shin D, et al. A novel cromakalim analogue induces cell cycle arrest and apoptosis in human cervical carcinoma HeLa cells through the caspase- and mitochondria-dependent pathway. Int J Oncol. 2011;39:1609-17 pubmed publisher

Florence X, Dilly S, de Tullio P, Pirotte B, Lebrun P. Modulation of the 6-position of benzopyran derivatives and inhibitory effects on the insulin releasing process. Bioorg Med Chem. 2011;19:3919-28 pubmed publisher

Tsuburaya R, Yasuda S, Ito Y, Shiroto T, Gao J, Ito K, et al. Eicosapentaenoic acid reduces ischemic ventricular fibrillation via altering monophasic action potential in pigs. J Mol Cell Cardiol. 2011;51:329-36 pubmed publisher

Vahabi B, Lawson K, McKay N, Sellers D. Phasic activity of urinary bladder smooth muscle in the streptozotocin-induced diabetic rat: effect of potassium channel modulators. Eur J Pharmacol. 2011;660:431-7 pubmed publisher

Khanna N, Malhotra R, Mehta A, Garg G, Halder S, Sharma K. Potassium channel openers exhibit cross-tolerance with morphine in two experimental models of pain. West Indian Med J. 2010;59:473-8 pubmed

Institoris A, Snipes J, Katakam P, Domoki F, Boda K, Bari F, et al. Impaired vascular responses of insulin-resistant rats after mild subarachnoid hemorrhage. Am J Physiol Heart Circ Physiol. 2011;300:H2080-7 pubmed publisher

Shimizu S, Saito M, Kinoshita Y, Ohmasa F, Dimitriadis F, Shomori K, et al. Nicorandil ameliorates ischaemia-reperfusion injury in the rat kidney. Br J Pharmacol. 2011;163:272-82 pubmed publisher

Jesse C, Wilhelm E, Bortolatto C, Nogueira C. Role of different types of potassium channels and peroxisome proliferator-activated receptors γ in the antidepressant-like activity of bis selenide in the mouse tail suspension test. Neurosci Lett. 2011;490:205-8 pubmed publisher

Khanna N, Malhotra R, Mehta A, Garg G, Halder S, Sharma K. Interaction of morphine and potassium channel openers on experimental models of pain in mice. Fundam Clin Pharmacol. 2011;25:479-84 pubmed publisher

Wilhelm E, Jesse C, Bortolatto C, Barbosa N, Nogueira C. Evidence of the involvement of K+ channels and PPARgamma receptors in the antidepressant-like activity of diphenyl diselenide in mice. J Pharm Pharmacol. 2010;62:1121-7 pubmed publisher

Testai L, Cecchetti V, Sabatini S, Martelli A, Breschi M, Calderone V. Effects of K openers on the QT prolongation induced by HERG-blocking drugs in guinea-pigs. J Pharm Pharmacol. 2010;62:924-30 pubmed publisher

Cecchetti V, Tabarrini O, Sabatini S. From cromakalim to different structural classes of K(ATP) channel openers. Curr Top Med Chem. 2006;6:1049-68 pubmed

Sebille S, de Tullio P, Boverie S, Antoine M, Lebrun P, Pirotte B. Recent developments in the chemistry of potassium channel activators: the cromakalim analogs. Curr Med Chem. 2004;11:1213-22 pubmed

Lijnen P, Fagard R, Staessen J, Weiping T, Moerman E, Amery A. Humoral and cellular effects of the K(+)-channel activator cromakalim in man. Eur J Clin Pharmacol. 1989;37:609-11 pubmed

Spinelli W, Follmer C, Parsons R, Colatsky T. Effects of cromakalim, pinacidil and nicorandil on cardiac refractoriness and arterial pressure in open-chest dogs. Eur J Pharmacol. 1990;179:243-52 pubmed